Amino acid dipepetide frequency for Luteitalea sp.

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.913AlaAla: 14.913 ± 0.144	1.146AlaCys: 1.146 ± 0.027	5.861AlaAsp: 5.861 ± 0.064	6.452AlaGlu: 6.452 ± 0.063	4.06AlaPhe: 4.06 ± 0.049	9.312AlaGly: 9.312 ± 0.08	2.371AlaHis: 2.371 ± 0.04	5.033AlaIle: 5.033 ± 0.064	2.236AlaLys: 2.236 ± 0.041	12.985AlaLeu: 12.985 ± 0.118	2.318AlaMet: 2.318 ± 0.031	2.641AlaAsn: 2.641 ± 0.038	5.463AlaPro: 5.463 ± 0.057	3.661AlaGln: 3.661 ± 0.046	10.414AlaArg: 10.414 ± 0.095	6.695AlaSer: 6.695 ± 0.063	6.463AlaThr: 6.463 ± 0.064	9.193AlaVal: 9.193 ± 0.079	1.697AlaTrp: 1.697 ± 0.034	2.476AlaTyr: 2.476 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	0.962CysAla: 0.962 ± 0.025	0.139CysCys: 0.139 ± 0.009	0.459CysAsp: 0.459 ± 0.016	0.382CysGlu: 0.382 ± 0.016	0.269CysPhe: 0.269 ± 0.011	0.839CysGly: 0.839 ± 0.025	0.251CysHis: 0.251 ± 0.014	0.237CysIle: 0.237 ± 0.012	0.118CysLys: 0.118 ± 0.008	0.756CysLeu: 0.756 ± 0.019	0.126CysMet: 0.126 ± 0.007	0.18CysAsn: 0.18 ± 0.01	0.396CysPro: 0.396 ± 0.016	0.219CysGln: 0.219 ± 0.01	0.691CysArg: 0.691 ± 0.019	0.428CysSer: 0.428 ± 0.014	0.404CysThr: 0.404 ± 0.016	0.599CysVal: 0.599 ± 0.019	0.114CysTrp: 0.114 ± 0.007	0.209CysTyr: 0.209 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.66AspAla: 6.66 ± 0.058	0.337AspCys: 0.337 ± 0.013	2.999AspAsp: 2.999 ± 0.044	3.74AspGlu: 3.74 ± 0.044	1.981AspPhe: 1.981 ± 0.035	5.076AspGly: 5.076 ± 0.062	1.234AspHis: 1.234 ± 0.029	2.225AspIle: 2.225 ± 0.035	0.987AspLys: 0.987 ± 0.028	5.652AspLeu: 5.652 ± 0.05	0.83AspMet: 0.83 ± 0.023	1.162AspAsn: 1.162 ± 0.035	3.947AspPro: 3.947 ± 0.049	1.763AspGln: 1.763 ± 0.032	5.021AspArg: 5.021 ± 0.054	2.128AspSer: 2.128 ± 0.035	2.714AspThr: 2.714 ± 0.037	5.184AspVal: 5.184 ± 0.062	0.937AspTrp: 0.937 ± 0.019	1.414AspTyr: 1.414 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	6.787GluAla: 6.787 ± 0.074	0.319GluCys: 0.319 ± 0.013	2.536GluAsp: 2.536 ± 0.038	3.205GluGlu: 3.205 ± 0.05	1.666GluPhe: 1.666 ± 0.025	4.214GluGly: 4.214 ± 0.046	1.472GluHis: 1.472 ± 0.028	2.948GluIle: 2.948 ± 0.044	1.354GluLys: 1.354 ± 0.033	5.938GluLeu: 5.938 ± 0.053	1.263GluMet: 1.263 ± 0.025	1.255GluAsn: 1.255 ± 0.03	3.131GluPro: 3.131 ± 0.045	2.405GluGln: 2.405 ± 0.041	6.038GluArg: 6.038 ± 0.053	2.731GluSer: 2.731 ± 0.043	3.18GluThr: 3.18 ± 0.046	4.235GluVal: 4.235 ± 0.051	0.799GluTrp: 0.799 ± 0.022	1.27GluTyr: 1.27 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	3.883PheAla: 3.883 ± 0.041	0.272PheCys: 0.272 ± 0.012	2.577PheAsp: 2.577 ± 0.04	2.196PheGlu: 2.196 ± 0.034	1.544PhePhe: 1.544 ± 0.034	3.639PheGly: 3.639 ± 0.056	0.814PheHis: 0.814 ± 0.022	1.177PheIle: 1.177 ± 0.028	0.754PheLys: 0.754 ± 0.021	3.196PheLeu: 3.196 ± 0.049	0.601PheMet: 0.601 ± 0.019	1.125PheAsn: 1.125 ± 0.032	1.738PhePro: 1.738 ± 0.038	1.06PheGln: 1.06 ± 0.022	2.684PheArg: 2.684 ± 0.043	2.242PheSer: 2.242 ± 0.045	2.264PheThr: 2.264 ± 0.034	2.979PheVal: 2.979 ± 0.032	0.567PheTrp: 0.567 ± 0.019	1.047PheTyr: 1.047 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	8.754GlyAla: 8.754 ± 0.083	0.755GlyCys: 0.755 ± 0.024	4.513GlyAsp: 4.513 ± 0.054	4.329GlyGlu: 4.329 ± 0.046	3.355GlyPhe: 3.355 ± 0.053	7.026GlyGly: 7.026 ± 0.081	1.856GlyHis: 1.856 ± 0.032	3.709GlyIle: 3.709 ± 0.045	2.06GlyLys: 2.06 ± 0.042	8.598GlyLeu: 8.598 ± 0.072	1.715GlyMet: 1.715 ± 0.03	2.138GlyAsn: 2.138 ± 0.044	3.656GlyPro: 3.656 ± 0.042	2.822GlyGln: 2.822 ± 0.033	7.857GlyArg: 7.857 ± 0.064	4.826GlySer: 4.826 ± 0.054	5.127GlyThr: 5.127 ± 0.055	7.312GlyVal: 7.312 ± 0.068	1.486GlyTrp: 1.486 ± 0.027	2.224GlyTyr: 2.224 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	2.561HisAla: 2.561 ± 0.037	0.185HisCys: 0.185 ± 0.01	1.275HisAsp: 1.275 ± 0.024	1.3HisGlu: 1.3 ± 0.029	0.787HisPhe: 0.787 ± 0.02	2.103HisGly: 2.103 ± 0.038	0.62HisHis: 0.62 ± 0.02	0.838HisIle: 0.838 ± 0.018	0.361HisLys: 0.361 ± 0.013	2.219HisLeu: 2.219 ± 0.035	0.364HisMet: 0.364 ± 0.014	0.511HisAsn: 0.511 ± 0.015	1.476HisPro: 1.476 ± 0.028	0.689HisGln: 0.689 ± 0.019	1.841HisArg: 1.841 ± 0.036	0.946HisSer: 0.946 ± 0.021	1.125HisThr: 1.125 ± 0.027	2.038HisVal: 2.038 ± 0.037	0.392HisTrp: 0.392 ± 0.015	0.627HisTyr: 0.627 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	5.08IleAla: 5.08 ± 0.061	0.324IleCys: 0.324 ± 0.013	3.036IleAsp: 3.036 ± 0.039	2.923IleGlu: 2.923 ± 0.042	1.312IlePhe: 1.312 ± 0.025	4.058IleGly: 4.058 ± 0.053	0.826IleHis: 0.826 ± 0.021	1.428IleIle: 1.428 ± 0.033	0.853IleLys: 0.853 ± 0.023	3.334IleLeu: 3.334 ± 0.044	0.497IleMet: 0.497 ± 0.015	1.066IleAsn: 1.066 ± 0.03	2.191IlePro: 2.191 ± 0.032	1.221IleGln: 1.221 ± 0.024	3.285IleArg: 3.285 ± 0.047	2.103IleSer: 2.103 ± 0.033	2.371IleThr: 2.371 ± 0.036	3.961IleVal: 3.961 ± 0.053	0.535IleTrp: 0.535 ± 0.017	1.001IleTyr: 1.001 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	2.297LysAla: 2.297 ± 0.043	0.123LysCys: 0.123 ± 0.009	1.115LysAsp: 1.115 ± 0.028	1.212LysGlu: 1.212 ± 0.028	0.546LysPhe: 0.546 ± 0.018	1.653LysGly: 1.653 ± 0.031	0.525LysHis: 0.525 ± 0.017	0.953LysIle: 0.953 ± 0.026	0.678LysLys: 0.678 ± 0.019	2.111LysLeu: 2.111 ± 0.033	0.444LysMet: 0.444 ± 0.018	0.53LysAsn: 0.53 ± 0.016	1.345LysPro: 1.345 ± 0.028	0.781LysGln: 0.781 ± 0.023	1.923LysArg: 1.923 ± 0.033	1.132LysSer: 1.132 ± 0.025	1.354LysThr: 1.354 ± 0.028	1.614LysVal: 1.614 ± 0.033	0.309LysTrp: 0.309 ± 0.013	0.553LysTyr: 0.553 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	13.174LeuAla: 13.174 ± 0.109	0.809LeuCys: 0.809 ± 0.023	6.035LeuAsp: 6.035 ± 0.057	5.85LeuGlu: 5.85 ± 0.064	3.551LeuPhe: 3.551 ± 0.05	8.691LeuGly: 8.691 ± 0.083	2.063LeuHis: 2.063 ± 0.038	3.77LeuIle: 3.77 ± 0.049	2.399LeuLys: 2.399 ± 0.042	10.876LeuLeu: 10.876 ± 0.112	1.792LeuMet: 1.792 ± 0.033	2.282LeuAsn: 2.282 ± 0.043	5.722LeuPro: 5.722 ± 0.057	3.25LeuGln: 3.25 ± 0.048	8.625LeuArg: 8.625 ± 0.068	5.807LeuSer: 5.807 ± 0.056	6.132LeuThr: 6.132 ± 0.061	8.964LeuVal: 8.964 ± 0.073	1.361LeuTrp: 1.361 ± 0.033	2.258LeuTyr: 2.258 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	2.228MetAla: 2.228 ± 0.033	0.133MetCys: 0.133 ± 0.009	0.819MetAsp: 0.819 ± 0.023	0.799MetGlu: 0.799 ± 0.019	0.552MetPhe: 0.552 ± 0.017	1.338MetGly: 1.338 ± 0.029	0.395MetHis: 0.395 ± 0.015	0.744MetIle: 0.744 ± 0.022	0.591MetLys: 0.591 ± 0.019	2.018MetLeu: 2.018 ± 0.033	0.415MetMet: 0.415 ± 0.014	0.522MetAsn: 0.522 ± 0.017	1.239MetPro: 1.239 ± 0.028	0.6MetGln: 0.6 ± 0.017	1.796MetArg: 1.796 ± 0.03	1.291MetSer: 1.291 ± 0.025	1.427MetThr: 1.427 ± 0.029	1.412MetVal: 1.412 ± 0.027	0.22MetTrp: 0.22 ± 0.011	0.33MetTyr: 0.33 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.558AsnAla: 2.558 ± 0.04	0.163AsnCys: 0.163 ± 0.009	1.359AsnAsp: 1.359 ± 0.034	1.258AsnGlu: 1.258 ± 0.029	0.949AsnPhe: 0.949 ± 0.031	2.185AsnGly: 2.185 ± 0.042	0.554AsnHis: 0.554 ± 0.017	1.073AsnIle: 1.073 ± 0.026	0.413AsnLys: 0.413 ± 0.013	2.541AsnLeu: 2.541 ± 0.048	0.399AsnMet: 0.399 ± 0.014	0.773AsnAsn: 0.773 ± 0.029	1.799AsnPro: 1.799 ± 0.039	0.841AsnGln: 0.841 ± 0.028	1.933AsnArg: 1.933 ± 0.036	1.012AsnSer: 1.012 ± 0.028	1.382AsnThr: 1.382 ± 0.032	2.378AsnVal: 2.378 ± 0.043	0.417AsnTrp: 0.417 ± 0.016	0.691AsnTyr: 0.691 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.111ProAla: 6.111 ± 0.056	0.338ProCys: 0.338 ± 0.013	3.955ProAsp: 3.955 ± 0.047	3.653ProGlu: 3.653 ± 0.045	2.154ProPhe: 2.154 ± 0.038	5.045ProGly: 5.045 ± 0.056	1.276ProHis: 1.276 ± 0.031	2.207ProIle: 2.207 ± 0.032	1.102ProLys: 1.102 ± 0.023	5.303ProLeu: 5.303 ± 0.05	1.081ProMet: 1.081 ± 0.024	1.539ProAsn: 1.539 ± 0.036	3.246ProPro: 3.246 ± 0.056	1.69ProGln: 1.69 ± 0.025	4.266ProArg: 4.266 ± 0.051	3.372ProSer: 3.372 ± 0.041	3.176ProThr: 3.176 ± 0.045	4.108ProVal: 4.108 ± 0.047	0.823ProTrp: 0.823 ± 0.018	1.285ProTyr: 1.285 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	3.775GlnAla: 3.775 ± 0.059	0.187GlnCys: 0.187 ± 0.011	1.516GlnAsp: 1.516 ± 0.031	1.739GlnGlu: 1.739 ± 0.03	1.242GlnPhe: 1.242 ± 0.03	2.383GlnGly: 2.383 ± 0.041	0.821GlnHis: 0.821 ± 0.02	1.498GlnIle: 1.498 ± 0.03	0.727GlnLys: 0.727 ± 0.018	3.299GlnLeu: 3.299 ± 0.043	0.679GlnMet: 0.679 ± 0.018	0.723GlnAsn: 0.723 ± 0.02	2.145GlnPro: 2.145 ± 0.03	1.456GlnGln: 1.456 ± 0.031	3.171GlnArg: 3.171 ± 0.044	1.655GlnSer: 1.655 ± 0.033	1.811GlnThr: 1.811 ± 0.031	2.614GlnVal: 2.614 ± 0.041	0.505GlnTrp: 0.505 ± 0.018	0.772GlnTyr: 0.772 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	9.788ArgAla: 9.788 ± 0.08	0.655ArgCys: 0.655 ± 0.02	4.831ArgAsp: 4.831 ± 0.048	5.232ArgGlu: 5.232 ± 0.057	3.47ArgPhe: 3.47 ± 0.046	6.287ArgGly: 6.287 ± 0.063	2.167ArgHis: 2.167 ± 0.034	3.721ArgIle: 3.721 ± 0.043	1.719ArgLys: 1.719 ± 0.034	9.649ArgLeu: 9.649 ± 0.074	1.869ArgMet: 1.869 ± 0.032	2.016ArgAsn: 2.016 ± 0.038	4.61ArgPro: 4.61 ± 0.051	3.201ArgGln: 3.201 ± 0.045	8.205ArgArg: 8.205 ± 0.077	4.618ArgSer: 4.618 ± 0.052	4.751ArgThr: 4.751 ± 0.048	7.168ArgVal: 7.168 ± 0.07	1.497ArgTrp: 1.497 ± 0.029	2.359ArgTyr: 2.359 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	6.05SerAla: 6.05 ± 0.061	0.434SerCys: 0.434 ± 0.016	2.887SerAsp: 2.887 ± 0.04	2.687SerGlu: 2.687 ± 0.038	2.135SerPhe: 2.135 ± 0.034	5.31SerGly: 5.31 ± 0.059	1.174SerHis: 1.174 ± 0.023	2.24SerIle: 2.24 ± 0.033	1.087SerLys: 1.087 ± 0.025	5.607SerLeu: 5.607 ± 0.066	1.109SerMet: 1.109 ± 0.025	1.328SerAsn: 1.328 ± 0.031	3.328SerPro: 3.328 ± 0.044	1.617SerGln: 1.617 ± 0.033	4.669SerArg: 4.669 ± 0.05	3.43SerSer: 3.43 ± 0.046	3.109SerThr: 3.109 ± 0.038	4.432SerVal: 4.432 ± 0.051	0.843SerTrp: 0.843 ± 0.023	1.438SerTyr: 1.438 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.234ThrAla: 6.234 ± 0.056	0.442ThrCys: 0.442 ± 0.015	3.024ThrAsp: 3.024 ± 0.042	2.789ThrGlu: 2.789 ± 0.043	2.408ThrPhe: 2.408 ± 0.039	4.93ThrGly: 4.93 ± 0.057	1.155ThrHis: 1.155 ± 0.026	2.755ThrIle: 2.755 ± 0.035	1.16ThrLys: 1.16 ± 0.027	6.642ThrLeu: 6.642 ± 0.067	1.128ThrMet: 1.128 ± 0.025	1.623ThrAsn: 1.623 ± 0.038	3.68ThrPro: 3.68 ± 0.044	1.433ThrGln: 1.433 ± 0.028	4.568ThrArg: 4.568 ± 0.054	3.371ThrSer: 3.371 ± 0.045	3.486ThrThr: 3.486 ± 0.056	4.761ThrVal: 4.761 ± 0.055	0.968ThrTrp: 0.968 ± 0.028	1.398ThrTyr: 1.398 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	9.865ValAla: 9.865 ± 0.099	0.664ValCys: 0.664 ± 0.019	4.893ValAsp: 4.893 ± 0.056	4.767ValGlu: 4.767 ± 0.053	2.696ValPhe: 2.696 ± 0.041	6.74ValGly: 6.74 ± 0.067	1.693ValHis: 1.693 ± 0.031	3.422ValIle: 3.422 ± 0.043	1.721ValLys: 1.721 ± 0.033	8.572ValLeu: 8.572 ± 0.079	1.535ValMet: 1.535 ± 0.031	2.111ValAsn: 2.111 ± 0.038	4.483ValPro: 4.483 ± 0.043	2.427ValGln: 2.427 ± 0.037	7.068ValArg: 7.068 ± 0.07	4.974ValSer: 4.974 ± 0.05	5.421ValThr: 5.421 ± 0.055	7.301ValVal: 7.301 ± 0.082	1.071ValTrp: 1.071 ± 0.025	1.754ValTyr: 1.754 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.257TrpAla: 1.257 ± 0.026	0.124TrpCys: 0.124 ± 0.008	0.772TrpAsp: 0.772 ± 0.023	0.712TrpGlu: 0.712 ± 0.021	0.572TrpPhe: 0.572 ± 0.017	1.052TrpGly: 1.052 ± 0.026	0.428TrpHis: 0.428 ± 0.015	0.663TrpIle: 0.663 ± 0.019	0.433TrpLys: 0.433 ± 0.015	1.724TrpLeu: 1.724 ± 0.031	0.378TrpMet: 0.378 ± 0.013	0.51TrpAsn: 0.51 ± 0.019	0.821TrpPro: 0.821 ± 0.021	0.713TrpGln: 0.713 ± 0.019	1.508TrpArg: 1.508 ± 0.028	0.967TrpSer: 0.967 ± 0.025	0.938TrpThr: 0.938 ± 0.023	1.012TrpVal: 1.012 ± 0.023	0.301TrpTrp: 0.301 ± 0.016	0.379TrpTyr: 0.379 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.452TyrAla: 2.452 ± 0.038	0.23TyrCys: 0.23 ± 0.011	1.528TyrAsp: 1.528 ± 0.031	1.517TyrGlu: 1.517 ± 0.033	1.112TyrPhe: 1.112 ± 0.026	2.236TyrGly: 2.236 ± 0.037	0.565TyrHis: 0.565 ± 0.019	0.765TyrIle: 0.765 ± 0.021	0.443TyrLys: 0.443 ± 0.014	2.389TyrLeu: 2.389 ± 0.036	0.326TyrMet: 0.326 ± 0.013	0.643TyrAsn: 0.643 ± 0.02	1.315TyrPro: 1.315 ± 0.029	0.869TyrGln: 0.869 ± 0.023	2.249TyrArg: 2.249 ± 0.035	1.189TyrSer: 1.189 ± 0.028	1.321TyrThr: 1.321 ± 0.032	1.911TyrVal: 1.911 ± 0.035	0.424TyrTrp: 0.424 ± 0.016	0.749TyrTyr: 0.749 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5191 proteins (1943161 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---