Amino acid dipepetide frequency for Posidoniimonas polymericola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.019AlaAla: 17.019 ± 0.146	1.325AlaCys: 1.325 ± 0.032	7.48AlaAsp: 7.48 ± 0.071	7.733AlaGlu: 7.733 ± 0.084	3.534AlaPhe: 3.534 ± 0.047	10.233AlaGly: 10.233 ± 0.082	1.8AlaHis: 1.8 ± 0.028	5.063AlaIle: 5.063 ± 0.068	3.524AlaLys: 3.524 ± 0.066	9.712AlaLeu: 9.712 ± 0.088	2.631AlaMet: 2.631 ± 0.044	3.178AlaAsn: 3.178 ± 0.046	6.078AlaPro: 6.078 ± 0.073	3.51AlaGln: 3.51 ± 0.046	6.42AlaArg: 6.42 ± 0.081	6.941AlaSer: 6.941 ± 0.074	6.294AlaThr: 6.294 ± 0.067	8.575AlaVal: 8.575 ± 0.076	1.678AlaTrp: 1.678 ± 0.035	2.584AlaTyr: 2.584 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.829CysAla: 0.829 ± 0.023	0.275CysCys: 0.275 ± 0.018	0.709CysAsp: 0.709 ± 0.02	0.675CysGlu: 0.675 ± 0.024	0.375CysPhe: 0.375 ± 0.016	1.204CysGly: 1.204 ± 0.032	0.328CysHis: 0.328 ± 0.016	0.332CysIle: 0.332 ± 0.013	0.246CysLys: 0.246 ± 0.013	1.17CysLeu: 1.17 ± 0.027	0.174CysMet: 0.174 ± 0.01	0.246CysAsn: 0.246 ± 0.012	0.642CysPro: 0.642 ± 0.02	0.386CysGln: 0.386 ± 0.014	0.885CysArg: 0.885 ± 0.023	0.612CysSer: 0.612 ± 0.016	0.481CysThr: 0.481 ± 0.016	0.875CysVal: 0.875 ± 0.022	0.173CysTrp: 0.173 ± 0.01	0.298CysTyr: 0.298 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.656AspAla: 7.656 ± 0.078	0.599AspCys: 0.599 ± 0.022	4.121AspAsp: 4.121 ± 0.069	4.133AspGlu: 4.133 ± 0.05	2.399AspPhe: 2.399 ± 0.044	6.132AspGly: 6.132 ± 0.12	1.407AspHis: 1.407 ± 0.032	2.204AspIle: 2.204 ± 0.039	1.655AspLys: 1.655 ± 0.032	6.119AspLeu: 6.119 ± 0.067	0.952AspMet: 0.952 ± 0.024	1.77AspAsn: 1.77 ± 0.037	3.98AspPro: 3.98 ± 0.053	2.618AspGln: 2.618 ± 0.044	4.198AspArg: 4.198 ± 0.054	3.494AspSer: 3.494 ± 0.054	2.487AspThr: 2.487 ± 0.044	3.767AspVal: 3.767 ± 0.048	1.163AspTrp: 1.163 ± 0.028	2.06AspTyr: 2.06 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.371GluAla: 6.371 ± 0.069	0.559GluCys: 0.559 ± 0.02	2.936GluAsp: 2.936 ± 0.047	3.752GluGlu: 3.752 ± 0.061	2.203GluPhe: 2.203 ± 0.038	4.298GluGly: 4.298 ± 0.055	1.47GluHis: 1.47 ± 0.032	2.818GluIle: 2.818 ± 0.043	1.892GluLys: 1.892 ± 0.048	7.287GluLeu: 7.287 ± 0.09	1.383GluMet: 1.383 ± 0.03	1.657GluAsn: 1.657 ± 0.033	3.538GluPro: 3.538 ± 0.05	3.22GluGln: 3.22 ± 0.052	4.517GluArg: 4.517 ± 0.065	3.842GluSer: 3.842 ± 0.047	2.874GluThr: 2.874 ± 0.045	4.639GluVal: 4.639 ± 0.055	0.92GluTrp: 0.92 ± 0.027	1.424GluTyr: 1.424 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	3.802PheAla: 3.802 ± 0.051	0.458PheCys: 0.458 ± 0.018	2.757PheAsp: 2.757 ± 0.042	2.215PheGlu: 2.215 ± 0.034	1.216PhePhe: 1.216 ± 0.026	3.25PheGly: 3.25 ± 0.051	0.635PheHis: 0.635 ± 0.019	1.101PheIle: 1.101 ± 0.029	0.827PheLys: 0.827 ± 0.023	2.834PheLeu: 2.834 ± 0.043	0.569PheMet: 0.569 ± 0.017	1.187PheAsn: 1.187 ± 0.032	1.443PhePro: 1.443 ± 0.031	1.064PheGln: 1.064 ± 0.023	2.083PheArg: 2.083 ± 0.034	2.182PheSer: 2.182 ± 0.044	1.99PheThr: 1.99 ± 0.039	2.574PheVal: 2.574 ± 0.035	0.526PheTrp: 0.526 ± 0.02	0.953PheTyr: 0.953 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	8.969GlyAla: 8.969 ± 0.082	1.041GlyCys: 1.041 ± 0.034	5.878GlyAsp: 5.878 ± 0.098	5.633GlyGlu: 5.633 ± 0.067	3.061GlyPhe: 3.061 ± 0.045	8.534GlyGly: 8.534 ± 0.123	1.599GlyHis: 1.599 ± 0.028	3.071GlyIle: 3.071 ± 0.047	2.85GlyLys: 2.85 ± 0.044	7.808GlyLeu: 7.808 ± 0.087	1.953GlyMet: 1.953 ± 0.039	2.235GlyAsn: 2.235 ± 0.051	3.958GlyPro: 3.958 ± 0.047	3.28GlyGln: 3.28 ± 0.043	5.721GlyArg: 5.721 ± 0.063	5.328GlySer: 5.328 ± 0.096	3.669GlyThr: 3.669 ± 0.07	7.695GlyVal: 7.695 ± 0.068	1.55GlyTrp: 1.55 ± 0.035	2.442GlyTyr: 2.442 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.228HisAla: 2.228 ± 0.04	0.303HisCys: 0.303 ± 0.015	1.392HisAsp: 1.392 ± 0.031	1.237HisGlu: 1.237 ± 0.032	0.748HisPhe: 0.748 ± 0.022	1.878HisGly: 1.878 ± 0.035	0.596HisHis: 0.596 ± 0.022	0.685HisIle: 0.685 ± 0.021	0.508HisLys: 0.508 ± 0.016	1.903HisLeu: 1.903 ± 0.033	0.329HisMet: 0.329 ± 0.013	0.624HisAsn: 0.624 ± 0.018	1.275HisPro: 1.275 ± 0.027	0.785HisGln: 0.785 ± 0.021	1.436HisArg: 1.436 ± 0.031	1.117HisSer: 1.117 ± 0.027	1.017HisThr: 1.017 ± 0.023	1.365HisVal: 1.365 ± 0.029	0.384HisTrp: 0.384 ± 0.017	0.634HisTyr: 0.634 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.377IleAla: 5.377 ± 0.058	0.447IleCys: 0.447 ± 0.017	3.501IleAsp: 3.501 ± 0.047	3.266IleGlu: 3.266 ± 0.045	0.954IlePhe: 0.954 ± 0.023	4.044IleGly: 4.044 ± 0.052	0.744IleHis: 0.744 ± 0.02	1.375IleIle: 1.375 ± 0.033	1.151IleLys: 1.151 ± 0.028	2.92IleLeu: 2.92 ± 0.042	0.574IleMet: 0.574 ± 0.018	1.375IleAsn: 1.375 ± 0.038	1.836IlePro: 1.836 ± 0.033	1.162IleGln: 1.162 ± 0.027	2.394IleArg: 2.394 ± 0.046	2.331IleSer: 2.331 ± 0.039	2.312IleThr: 2.312 ± 0.048	3.217IleVal: 3.217 ± 0.043	0.428IleTrp: 0.428 ± 0.016	0.95IleTyr: 0.95 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	2.635LysAla: 2.635 ± 0.047	0.267LysCys: 0.267 ± 0.013	1.276LysAsp: 1.276 ± 0.03	1.504LysGlu: 1.504 ± 0.036	0.879LysPhe: 0.879 ± 0.021	1.652LysGly: 1.652 ± 0.04	0.693LysHis: 0.693 ± 0.022	1.362LysIle: 1.362 ± 0.034	1.29LysLys: 1.29 ± 0.051	3.369LysLeu: 3.369 ± 0.049	0.628LysMet: 0.628 ± 0.023	0.844LysAsn: 0.844 ± 0.024	1.949LysPro: 1.949 ± 0.04	1.58LysGln: 1.58 ± 0.034	1.992LysArg: 1.992 ± 0.035	1.766LysSer: 1.766 ± 0.036	1.604LysThr: 1.604 ± 0.034	1.957LysVal: 1.957 ± 0.037	0.439LysTrp: 0.439 ± 0.018	0.718LysTyr: 0.718 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	13.088LeuAla: 13.088 ± 0.118	1.096LeuCys: 1.096 ± 0.029	5.949LeuAsp: 5.949 ± 0.063	5.709LeuGlu: 5.709 ± 0.073	3.062LeuPhe: 3.062 ± 0.049	7.982LeuGly: 7.982 ± 0.073	1.988LeuHis: 1.988 ± 0.035	4.024LeuIle: 4.024 ± 0.053	2.845LeuLys: 2.845 ± 0.049	10.903LeuLeu: 10.903 ± 0.118	1.938LeuMet: 1.938 ± 0.035	2.73LeuAsn: 2.73 ± 0.046	5.656LeuPro: 5.656 ± 0.067	3.302LeuGln: 3.302 ± 0.052	6.852LeuArg: 6.852 ± 0.085	6.299LeuSer: 6.299 ± 0.065	5.969LeuThr: 5.969 ± 0.062	7.431LeuVal: 7.431 ± 0.074	1.333LeuTrp: 1.333 ± 0.03	2.153LeuTyr: 2.153 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.21MetAla: 2.21 ± 0.04	0.175MetCys: 0.175 ± 0.01	0.862MetAsp: 0.862 ± 0.021	0.842MetGlu: 0.842 ± 0.025	0.617MetPhe: 0.617 ± 0.02	1.359MetGly: 1.359 ± 0.03	0.449MetHis: 0.449 ± 0.016	0.93MetIle: 0.93 ± 0.022	0.71MetLys: 0.71 ± 0.021	2.294MetLeu: 2.294 ± 0.039	0.447MetMet: 0.447 ± 0.02	0.666MetAsn: 0.666 ± 0.019	1.376MetPro: 1.376 ± 0.029	0.895MetGln: 0.895 ± 0.022	1.333MetArg: 1.333 ± 0.027	1.316MetSer: 1.316 ± 0.029	1.361MetThr: 1.361 ± 0.029	1.423MetVal: 1.423 ± 0.03	0.219MetTrp: 0.219 ± 0.01	0.384MetTyr: 0.384 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.086AsnAla: 3.086 ± 0.046	0.302AsnCys: 0.302 ± 0.012	1.822AsnAsp: 1.822 ± 0.049	1.57AsnGlu: 1.57 ± 0.032	1.013AsnPhe: 1.013 ± 0.029	2.831AsnGly: 2.831 ± 0.065	0.628AsnHis: 0.628 ± 0.019	1.061AsnIle: 1.061 ± 0.027	0.644AsnLys: 0.644 ± 0.019	2.878AsnLeu: 2.878 ± 0.041	0.455AsnMet: 0.455 ± 0.019	1.054AsnAsn: 1.054 ± 0.033	1.996AsnPro: 1.996 ± 0.036	1.143AsnGln: 1.143 ± 0.024	1.98AsnArg: 1.98 ± 0.033	1.681AsnSer: 1.681 ± 0.044	1.464AsnThr: 1.464 ± 0.034	1.909AsnVal: 1.909 ± 0.032	0.502AsnTrp: 0.502 ± 0.017	0.904AsnTyr: 0.904 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	7.004ProAla: 7.004 ± 0.08	0.464ProCys: 0.464 ± 0.019	3.635ProAsp: 3.635 ± 0.052	3.978ProGlu: 3.978 ± 0.045	1.71ProPhe: 1.71 ± 0.03	4.808ProGly: 4.808 ± 0.055	1.089ProHis: 1.089 ± 0.025	2.28ProIle: 2.28 ± 0.039	1.479ProLys: 1.479 ± 0.033	5.123ProLeu: 5.123 ± 0.057	1.046ProMet: 1.046 ± 0.025	1.735ProAsn: 1.735 ± 0.034	3.374ProPro: 3.374 ± 0.061	1.986ProGln: 1.986 ± 0.041	3.154ProArg: 3.154 ± 0.045	3.524ProSer: 3.524 ± 0.046	3.499ProThr: 3.499 ± 0.048	3.891ProVal: 3.891 ± 0.05	0.797ProTrp: 0.797 ± 0.021	1.245ProTyr: 1.245 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	4.455GlnAla: 4.455 ± 0.052	0.321GlnCys: 0.321 ± 0.014	1.739GlnAsp: 1.739 ± 0.03	1.906GlnGlu: 1.906 ± 0.039	1.254GlnPhe: 1.254 ± 0.027	2.672GlnGly: 2.672 ± 0.042	0.847GlnHis: 0.847 ± 0.022	1.74GlnIle: 1.74 ± 0.035	0.965GlnLys: 0.965 ± 0.022	4.14GlnLeu: 4.14 ± 0.056	0.859GlnMet: 0.859 ± 0.024	1.002GlnAsn: 1.002 ± 0.029	2.395GlnPro: 2.395 ± 0.051	2.237GlnGln: 2.237 ± 0.054	2.874GlnArg: 2.874 ± 0.056	2.261GlnSer: 2.261 ± 0.04	2.165GlnThr: 2.165 ± 0.036	2.652GlnVal: 2.652 ± 0.043	0.601GlnTrp: 0.601 ± 0.018	0.852GlnTyr: 0.852 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	5.881ArgAla: 5.881 ± 0.068	0.755ArgCys: 0.755 ± 0.022	3.975ArgAsp: 3.975 ± 0.04	4.141ArgGlu: 4.141 ± 0.061	2.673ArgPhe: 2.673 ± 0.044	4.953ArgGly: 4.953 ± 0.066	1.491ArgHis: 1.491 ± 0.035	2.81ArgIle: 2.81 ± 0.042	1.822ArgLys: 1.822 ± 0.037	7.831ArgLeu: 7.831 ± 0.104	1.56ArgMet: 1.56 ± 0.031	1.723ArgAsn: 1.723 ± 0.032	3.617ArgPro: 3.617 ± 0.057	2.76ArgGln: 2.76 ± 0.047	6.176ArgArg: 6.176 ± 0.084	3.813ArgSer: 3.813 ± 0.05	3.19ArgThr: 3.19 ± 0.041	5.32ArgVal: 5.32 ± 0.066	1.182ArgTrp: 1.182 ± 0.028	1.788ArgTyr: 1.788 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.134SerAla: 6.134 ± 0.066	0.581SerCys: 0.581 ± 0.023	3.691SerAsp: 3.691 ± 0.051	3.404SerGlu: 3.404 ± 0.048	2.063SerPhe: 2.063 ± 0.035	6.167SerGly: 6.167 ± 0.099	1.263SerHis: 1.263 ± 0.03	2.556SerIle: 2.556 ± 0.041	1.595SerLys: 1.595 ± 0.035	6.216SerLeu: 6.216 ± 0.068	1.182SerMet: 1.182 ± 0.025	1.734SerAsn: 1.734 ± 0.038	3.709SerPro: 3.709 ± 0.048	2.184SerGln: 2.184 ± 0.032	3.911SerArg: 3.911 ± 0.051	3.849SerSer: 3.849 ± 0.074	3.366SerThr: 3.366 ± 0.06	4.524SerVal: 4.524 ± 0.055	0.896SerTrp: 0.896 ± 0.023	1.494SerTyr: 1.494 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	5.959ThrAla: 5.959 ± 0.064	0.511ThrCys: 0.511 ± 0.018	3.226ThrAsp: 3.226 ± 0.047	2.667ThrGlu: 2.667 ± 0.044	1.824ThrPhe: 1.824 ± 0.033	4.859ThrGly: 4.859 ± 0.068	1.136ThrHis: 1.136 ± 0.026	2.499ThrIle: 2.499 ± 0.046	1.412ThrLys: 1.412 ± 0.034	5.974ThrLeu: 5.974 ± 0.067	0.919ThrMet: 0.919 ± 0.023	1.595ThrAsn: 1.595 ± 0.036	3.941ThrPro: 3.941 ± 0.053	1.709ThrGln: 1.709 ± 0.031	3.02ThrArg: 3.02 ± 0.047	3.146ThrSer: 3.146 ± 0.051	3.17ThrThr: 3.17 ± 0.058	4.013ThrVal: 4.013 ± 0.073	0.658ThrTrp: 0.658 ± 0.021	1.277ThrTyr: 1.277 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	8.728ValAla: 8.728 ± 0.076	0.925ValCys: 0.925 ± 0.024	5.276ValAsp: 5.276 ± 0.061	4.944ValGlu: 4.944 ± 0.057	2.508ValPhe: 2.508 ± 0.043	6.071ValGly: 6.071 ± 0.062	1.369ValHis: 1.369 ± 0.029	3.13ValIle: 3.13 ± 0.045	1.901ValLys: 1.901 ± 0.035	7.48ValLeu: 7.48 ± 0.071	1.534ValMet: 1.534 ± 0.032	2.222ValAsn: 2.222 ± 0.05	3.187ValPro: 3.187 ± 0.045	2.352ValGln: 2.352 ± 0.034	5.031ValArg: 5.031 ± 0.065	4.448ValSer: 4.448 ± 0.049	4.434ValThr: 4.434 ± 0.07	6.653ValVal: 6.653 ± 0.085	1.169ValTrp: 1.169 ± 0.028	1.829ValTyr: 1.829 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.356TrpAla: 1.356 ± 0.03	0.174TrpCys: 0.174 ± 0.01	0.906TrpAsp: 0.906 ± 0.024	0.745TrpGlu: 0.745 ± 0.021	0.551TrpPhe: 0.551 ± 0.019	1.114TrpGly: 1.114 ± 0.028	0.334TrpHis: 0.334 ± 0.012	0.607TrpIle: 0.607 ± 0.02	0.489TrpLys: 0.489 ± 0.016	1.733TrpLeu: 1.733 ± 0.042	0.377TrpMet: 0.377 ± 0.016	0.491TrpAsn: 0.491 ± 0.016	0.76TrpPro: 0.76 ± 0.028	0.683TrpGln: 0.683 ± 0.024	1.512TrpArg: 1.512 ± 0.036	1.04TrpSer: 1.04 ± 0.028	0.858TrpThr: 0.858 ± 0.024	1.004TrpVal: 1.004 ± 0.023	0.303TrpTrp: 0.303 ± 0.016	0.34TrpTyr: 0.34 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.524TyrAla: 2.524 ± 0.043	0.338TyrCys: 0.338 ± 0.015	1.786TyrAsp: 1.786 ± 0.034	1.544TyrGlu: 1.544 ± 0.031	1.023TyrPhe: 1.023 ± 0.027	2.234TyrGly: 2.234 ± 0.038	0.58TyrHis: 0.58 ± 0.018	0.71TyrIle: 0.71 ± 0.024	0.599TyrLys: 0.599 ± 0.021	2.615TyrLeu: 2.615 ± 0.045	0.356TyrMet: 0.356 ± 0.013	0.853TyrAsn: 0.853 ± 0.022	1.109TyrPro: 1.109 ± 0.026	1.08TyrGln: 1.08 ± 0.025	1.972TyrArg: 1.972 ± 0.035	1.529TyrSer: 1.529 ± 0.038	1.31TyrThr: 1.31 ± 0.033	1.709TyrVal: 1.709 ± 0.033	0.459TyrTrp: 0.459 ± 0.019	0.858TyrTyr: 0.858 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4870 proteins (1793801 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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