Amino acid dipepetide frequency for Luteipulveratus mongoliensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.976AlaAla: 17.976 ± 0.147
0.939AlaCys: 0.939 ± 0.027
7.984AlaAsp: 7.984 ± 0.079
6.882AlaGlu: 6.882 ± 0.083
3.398AlaPhe: 3.398 ± 0.054
11.484AlaGly: 11.484 ± 0.099
2.592AlaHis: 2.592 ± 0.041
4.819AlaIle: 4.819 ± 0.063
3.211AlaLys: 3.211 ± 0.06
12.932AlaLeu: 12.932 ± 0.123
2.952AlaMet: 2.952 ± 0.039
2.083AlaAsn: 2.083 ± 0.036
5.884AlaPro: 5.884 ± 0.073
4.099AlaGln: 4.099 ± 0.061
8.584AlaArg: 8.584 ± 0.089
6.868AlaSer: 6.868 ± 0.074
7.713AlaThr: 7.713 ± 0.089
10.938AlaVal: 10.938 ± 0.1
1.868AlaTrp: 1.868 ± 0.037
2.891AlaTyr: 2.891 ± 0.041
0.0AlaXaa: 0.0 ± 0.0
Cys
0.895CysAla: 0.895 ± 0.024
0.083CysCys: 0.083 ± 0.008
0.442CysAsp: 0.442 ± 0.017
0.343CysGlu: 0.343 ± 0.016
0.23CysPhe: 0.23 ± 0.012
0.832CysGly: 0.832 ± 0.024
0.196CysHis: 0.196 ± 0.011
0.219CysIle: 0.219 ± 0.013
0.125CysLys: 0.125 ± 0.008
0.663CysLeu: 0.663 ± 0.023
0.131CysMet: 0.131 ± 0.009
0.145CysAsn: 0.145 ± 0.011
0.433CysPro: 0.433 ± 0.019
0.198CysGln: 0.198 ± 0.011
0.493CysArg: 0.493 ± 0.019
0.461CysSer: 0.461 ± 0.019
0.461CysThr: 0.461 ± 0.017
0.603CysVal: 0.603 ± 0.02
0.121CysTrp: 0.121 ± 0.008
0.164CysTyr: 0.164 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
7.729AspAla: 7.729 ± 0.085
0.358AspCys: 0.358 ± 0.018
4.341AspAsp: 4.341 ± 0.061
4.22AspGlu: 4.22 ± 0.066
1.579AspPhe: 1.579 ± 0.031
6.326AspGly: 6.326 ± 0.068
1.573AspHis: 1.573 ± 0.035
2.285AspIle: 2.285 ± 0.043
1.458AspLys: 1.458 ± 0.035
6.987AspLeu: 6.987 ± 0.082
0.943AspMet: 0.943 ± 0.025
1.218AspAsn: 1.218 ± 0.032
4.106AspPro: 4.106 ± 0.059
2.112AspGln: 2.112 ± 0.042
4.72AspArg: 4.72 ± 0.064
2.852AspSer: 2.852 ± 0.047
2.909AspThr: 2.909 ± 0.045
5.791AspVal: 5.791 ± 0.064
1.062AspTrp: 1.062 ± 0.029
1.269AspTyr: 1.269 ± 0.031
0.0AspXaa: 0.0 ± 0.0
Glu
6.301GluAla: 6.301 ± 0.092
0.328GluCys: 0.328 ± 0.017
2.953GluAsp: 2.953 ± 0.046
2.657GluGlu: 2.657 ± 0.051
1.374GluPhe: 1.374 ± 0.031
3.994GluGly: 3.994 ± 0.066
1.715GluHis: 1.715 ± 0.036
2.362GluIle: 2.362 ± 0.046
1.234GluLys: 1.234 ± 0.036
6.069GluLeu: 6.069 ± 0.076
1.063GluMet: 1.063 ± 0.026
0.84GluAsn: 0.84 ± 0.025
3.071GluPro: 3.071 ± 0.055
2.545GluGln: 2.545 ± 0.046
4.887GluArg: 4.887 ± 0.067
2.977GluSer: 2.977 ± 0.05
2.864GluThr: 2.864 ± 0.044
4.734GluVal: 4.734 ± 0.078
0.794GluTrp: 0.794 ± 0.026
0.892GluTyr: 0.892 ± 0.029
0.0GluXaa: 0.0 ± 0.0
Phe
3.487PheAla: 3.487 ± 0.054
0.255PheCys: 0.255 ± 0.014
2.005PheAsp: 2.005 ± 0.038
1.556PheGlu: 1.556 ± 0.034
0.907PhePhe: 0.907 ± 0.026
3.052PheGly: 3.052 ± 0.05
0.561PheHis: 0.561 ± 0.017
0.935PheIle: 0.935 ± 0.027
0.551PheLys: 0.551 ± 0.022
2.394PheLeu: 2.394 ± 0.044
0.457PheMet: 0.457 ± 0.02
0.673PheAsn: 0.673 ± 0.022
1.257PhePro: 1.257 ± 0.031
0.69PheGln: 0.69 ± 0.022
1.571PheArg: 1.571 ± 0.036
1.487PheSer: 1.487 ± 0.031
1.85PheThr: 1.85 ± 0.038
2.574PheVal: 2.574 ± 0.049
0.488PheTrp: 0.488 ± 0.019
0.605PheTyr: 0.605 ± 0.025
0.0PheXaa: 0.0 ± 0.0
Gly
9.983GlyAla: 9.983 ± 0.093
0.753GlyCys: 0.753 ± 0.023
5.224GlyAsp: 5.224 ± 0.073
4.589GlyGlu: 4.589 ± 0.058
2.91GlyPhe: 2.91 ± 0.047
7.885GlyGly: 7.885 ± 0.099
2.137GlyHis: 2.137 ± 0.037
3.688GlyIle: 3.688 ± 0.057
2.532GlyLys: 2.532 ± 0.055
9.355GlyLeu: 9.355 ± 0.085
1.972GlyMet: 1.972 ± 0.036
1.771GlyAsn: 1.771 ± 0.036
4.321GlyPro: 4.321 ± 0.058
3.073GlyGln: 3.073 ± 0.049
6.579GlyArg: 6.579 ± 0.069
5.705GlySer: 5.705 ± 0.064
5.535GlyThr: 5.535 ± 0.064
7.672GlyVal: 7.672 ± 0.082
1.833GlyTrp: 1.833 ± 0.038
2.266GlyTyr: 2.266 ± 0.046
0.0GlyXaa: 0.0 ± 0.0
His
2.489HisAla: 2.489 ± 0.047
0.177HisCys: 0.177 ± 0.012
1.615HisAsp: 1.615 ± 0.035
1.362HisGlu: 1.362 ± 0.03
0.593HisPhe: 0.593 ± 0.021
2.209HisGly: 2.209 ± 0.039
0.679HisHis: 0.679 ± 0.024
0.69HisIle: 0.69 ± 0.021
0.352HisLys: 0.352 ± 0.015
2.492HisLeu: 2.492 ± 0.042
0.333HisMet: 0.333 ± 0.016
0.396HisAsn: 0.396 ± 0.017
1.552HisPro: 1.552 ± 0.034
0.757HisGln: 0.757 ± 0.022
1.782HisArg: 1.782 ± 0.036
1.042HisSer: 1.042 ± 0.03
1.148HisThr: 1.148 ± 0.029
1.951HisVal: 1.951 ± 0.042
0.355HisTrp: 0.355 ± 0.015
0.483HisTyr: 0.483 ± 0.018
0.0HisXaa: 0.0 ± 0.0
Ile
5.531IleAla: 5.531 ± 0.066
0.337IleCys: 0.337 ± 0.016
3.007IleAsp: 3.007 ± 0.053
2.423IleGlu: 2.423 ± 0.045
0.956IlePhe: 0.956 ± 0.027
4.286IleGly: 4.286 ± 0.066
0.716IleHis: 0.716 ± 0.02
1.24IleIle: 1.24 ± 0.032
1.005IleLys: 1.005 ± 0.027
2.788IleLeu: 2.788 ± 0.048
0.55IleMet: 0.55 ± 0.021
0.97IleAsn: 0.97 ± 0.03
1.963IlePro: 1.963 ± 0.035
0.912IleGln: 0.912 ± 0.023
2.385IleArg: 2.385 ± 0.043
2.253IleSer: 2.253 ± 0.038
2.532IleThr: 2.532 ± 0.047
3.497IleVal: 3.497 ± 0.054
0.49IleTrp: 0.49 ± 0.019
0.716IleTyr: 0.716 ± 0.026
0.0IleXaa: 0.0 ± 0.0
Lys
3.274LysAla: 3.274 ± 0.06
0.116LysCys: 0.116 ± 0.009
1.548LysAsp: 1.548 ± 0.041
1.127LysGlu: 1.127 ± 0.029
0.505LysPhe: 0.505 ± 0.017
2.032LysGly: 2.032 ± 0.046
0.54LysHis: 0.54 ± 0.018
0.966LysIle: 0.966 ± 0.03
0.901LysLys: 0.901 ± 0.037
1.755LysLeu: 1.755 ± 0.039
0.428LysMet: 0.428 ± 0.018
0.559LysAsn: 0.559 ± 0.023
1.501LysPro: 1.501 ± 0.04
0.842LysGln: 0.842 ± 0.027
1.491LysArg: 1.491 ± 0.034
1.389LysSer: 1.389 ± 0.035
1.522LysThr: 1.522 ± 0.043
2.293LysVal: 2.293 ± 0.046
0.281LysTrp: 0.281 ± 0.014
0.49LysTyr: 0.49 ± 0.018
0.0LysXaa: 0.0 ± 0.0
Leu
13.796LeuAla: 13.796 ± 0.117
0.678LeuCys: 0.678 ± 0.024
6.817LeuAsp: 6.817 ± 0.074
4.969LeuGlu: 4.969 ± 0.072
2.307LeuPhe: 2.307 ± 0.04
9.041LeuGly: 9.041 ± 0.089
2.022LeuHis: 2.022 ± 0.039
3.871LeuIle: 3.871 ± 0.055
2.178LeuLys: 2.178 ± 0.045
10.09LeuLeu: 10.09 ± 0.104
1.893LeuMet: 1.893 ± 0.038
1.831LeuAsn: 1.831 ± 0.034
5.619LeuPro: 5.619 ± 0.067
2.761LeuGln: 2.761 ± 0.046
7.576LeuArg: 7.576 ± 0.084
5.969LeuSer: 5.969 ± 0.067
6.622LeuThr: 6.622 ± 0.076
9.449LeuVal: 9.449 ± 0.104
1.262LeuTrp: 1.262 ± 0.031
1.573LeuTyr: 1.573 ± 0.033
0.0LeuXaa: 0.0 ± 0.0
Met
2.424MetAla: 2.424 ± 0.043
0.154MetCys: 0.154 ± 0.011
0.95MetAsp: 0.95 ± 0.026
0.755MetGlu: 0.755 ± 0.021
0.548MetPhe: 0.548 ± 0.021
1.455MetGly: 1.455 ± 0.031
0.407MetHis: 0.407 ± 0.016
0.746MetIle: 0.746 ± 0.024
0.503MetLys: 0.503 ± 0.019
1.956MetLeu: 1.956 ± 0.037
0.312MetMet: 0.312 ± 0.015
0.429MetAsn: 0.429 ± 0.018
1.209MetPro: 1.209 ± 0.028
0.578MetGln: 0.578 ± 0.019
1.539MetArg: 1.539 ± 0.034
1.695MetSer: 1.695 ± 0.033
1.855MetThr: 1.855 ± 0.034
1.615MetVal: 1.615 ± 0.036
0.258MetTrp: 0.258 ± 0.012
0.318MetTyr: 0.318 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
2.347AsnAla: 2.347 ± 0.045
0.133AsnCys: 0.133 ± 0.01
1.194AsnAsp: 1.194 ± 0.028
0.913AsnGlu: 0.913 ± 0.025
0.498AsnPhe: 0.498 ± 0.018
1.933AsnGly: 1.933 ± 0.038
0.432AsnHis: 0.432 ± 0.017
0.715AsnIle: 0.715 ± 0.019
0.486AsnLys: 0.486 ± 0.021
1.896AsnLeu: 1.896 ± 0.039
0.274AsnMet: 0.274 ± 0.014
0.489AsnAsn: 0.489 ± 0.019
1.532AsnPro: 1.532 ± 0.033
0.561AsnGln: 0.561 ± 0.02
1.239AsnArg: 1.239 ± 0.029
0.916AsnSer: 0.916 ± 0.022
1.121AsnThr: 1.121 ± 0.033
1.67AsnVal: 1.67 ± 0.039
0.291AsnTrp: 0.291 ± 0.014
0.439AsnTyr: 0.439 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
6.85ProAla: 6.85 ± 0.077
0.31ProCys: 0.31 ± 0.016
4.29ProAsp: 4.29 ± 0.06
3.559ProGlu: 3.559 ± 0.058
1.488ProPhe: 1.488 ± 0.027
5.228ProGly: 5.228 ± 0.053
1.197ProHis: 1.197 ± 0.028
1.832ProIle: 1.832 ± 0.036
1.332ProLys: 1.332 ± 0.035
4.681ProLeu: 4.681 ± 0.065
1.136ProMet: 1.136 ± 0.027
1.025ProAsn: 1.025 ± 0.029
2.715ProPro: 2.715 ± 0.057
1.791ProGln: 1.791 ± 0.039
3.368ProArg: 3.368 ± 0.054
3.47ProSer: 3.47 ± 0.059
3.791ProThr: 3.791 ± 0.057
4.899ProVal: 4.899 ± 0.062
0.991ProTrp: 0.991 ± 0.025
1.183ProTyr: 1.183 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
3.923GlnAla: 3.923 ± 0.056
0.186GlnCys: 0.186 ± 0.013
1.662GlnAsp: 1.662 ± 0.034
1.526GlnGlu: 1.526 ± 0.029
0.752GlnPhe: 0.752 ± 0.025
2.381GlnGly: 2.381 ± 0.037
0.874GlnHis: 0.874 ± 0.022
1.456GlnIle: 1.456 ± 0.033
0.635GlnLys: 0.635 ± 0.022
3.506GlnLeu: 3.506 ± 0.06
0.658GlnMet: 0.658 ± 0.019
0.508GlnAsn: 0.508 ± 0.019
1.982GlnPro: 1.982 ± 0.042
1.468GlnGln: 1.468 ± 0.036
2.773GlnArg: 2.773 ± 0.045
1.608GlnSer: 1.608 ± 0.038
1.769GlnThr: 1.769 ± 0.04
3.12GlnVal: 3.12 ± 0.041
0.56GlnTrp: 0.56 ± 0.02
0.574GlnTyr: 0.574 ± 0.02
0.0GlnXaa: 0.0 ± 0.0
Arg
8.432ArgAla: 8.432 ± 0.093
0.536ArgCys: 0.536 ± 0.021
4.348ArgAsp: 4.348 ± 0.061
4.334ArgGlu: 4.334 ± 0.068
2.076ArgPhe: 2.076 ± 0.041
5.188ArgGly: 5.188 ± 0.062
1.716ArgHis: 1.716 ± 0.039
3.006ArgIle: 3.006 ± 0.041
1.533ArgLys: 1.533 ± 0.04
7.87ArgLeu: 7.87 ± 0.097
1.669ArgMet: 1.669 ± 0.034
1.267ArgAsn: 1.267 ± 0.031
4.131ArgPro: 4.131 ± 0.061
2.385ArgGln: 2.385 ± 0.042
6.736ArgArg: 6.736 ± 0.095
4.288ArgSer: 4.288 ± 0.049
4.845ArgThr: 4.845 ± 0.058
5.798ArgVal: 5.798 ± 0.073
1.425ArgTrp: 1.425 ± 0.029
1.623ArgTyr: 1.623 ± 0.032
0.0ArgXaa: 0.0 ± 0.0
Ser
7.102SerAla: 7.102 ± 0.066
0.43SerCys: 0.43 ± 0.018
3.328SerAsp: 3.328 ± 0.049
2.721SerGlu: 2.721 ± 0.048
1.638SerPhe: 1.638 ± 0.032
6.024SerGly: 6.024 ± 0.076
1.203SerHis: 1.203 ± 0.029
2.176SerIle: 2.176 ± 0.04
1.389SerLys: 1.389 ± 0.031
5.397SerLeu: 5.397 ± 0.063
1.427SerMet: 1.427 ± 0.033
1.133SerAsn: 1.133 ± 0.028
3.257SerPro: 3.257 ± 0.048
1.629SerGln: 1.629 ± 0.033
3.995SerArg: 3.995 ± 0.054
3.873SerSer: 3.873 ± 0.071
4.05SerThr: 4.05 ± 0.056
4.855SerVal: 4.855 ± 0.054
1.116SerTrp: 1.116 ± 0.025
1.526SerTyr: 1.526 ± 0.035
0.0SerXaa: 0.0 ± 0.0
Thr
7.611ThrAla: 7.611 ± 0.08
0.494ThrCys: 0.494 ± 0.018
3.722ThrAsp: 3.722 ± 0.06
2.976ThrGlu: 2.976 ± 0.051
2.055ThrPhe: 2.055 ± 0.038
5.837ThrGly: 5.837 ± 0.068
1.269ThrHis: 1.269 ± 0.029
2.539ThrIle: 2.539 ± 0.04
1.544ThrLys: 1.544 ± 0.038
5.831ThrLeu: 5.831 ± 0.064
1.25ThrMet: 1.25 ± 0.027
1.243ThrAsn: 1.243 ± 0.032
3.877ThrPro: 3.877 ± 0.054
1.731ThrGln: 1.731 ± 0.035
3.967ThrArg: 3.967 ± 0.056
4.097ThrSer: 4.097 ± 0.064
4.553ThrThr: 4.553 ± 0.069
5.839ThrVal: 5.839 ± 0.068
1.157ThrTrp: 1.157 ± 0.029
1.567ThrTyr: 1.567 ± 0.034
0.0ThrXaa: 0.0 ± 0.0
Val
11.404ValAla: 11.404 ± 0.11
0.654ValCys: 0.654 ± 0.018
5.633ValAsp: 5.633 ± 0.061
4.964ValGlu: 4.964 ± 0.065
2.297ValPhe: 2.297 ± 0.043
7.434ValGly: 7.434 ± 0.09
1.867ValHis: 1.867 ± 0.036
3.762ValIle: 3.762 ± 0.06
1.835ValLys: 1.835 ± 0.043
9.709ValLeu: 9.709 ± 0.117
1.697ValMet: 1.697 ± 0.037
1.68ValAsn: 1.68 ± 0.038
4.811ValPro: 4.811 ± 0.058
2.5ValGln: 2.5 ± 0.042
6.68ValArg: 6.68 ± 0.077
5.046ValSer: 5.046 ± 0.06
5.885ValThr: 5.885 ± 0.069
9.121ValVal: 9.121 ± 0.108
1.148ValTrp: 1.148 ± 0.029
1.438ValTyr: 1.438 ± 0.032
0.0ValXaa: 0.0 ± 0.0
Trp
1.714TrpAla: 1.714 ± 0.035
0.167TrpCys: 0.167 ± 0.01
0.943TrpAsp: 0.943 ± 0.024
0.691TrpGlu: 0.691 ± 0.022
0.573TrpPhe: 0.573 ± 0.023
1.136TrpGly: 1.136 ± 0.03
0.423TrpHis: 0.423 ± 0.018
0.653TrpIle: 0.653 ± 0.024
0.36TrpLys: 0.36 ± 0.018
1.824TrpLeu: 1.824 ± 0.042
0.33TrpMet: 0.33 ± 0.013
0.377TrpAsn: 0.377 ± 0.016
0.868TrpPro: 0.868 ± 0.025
0.681TrpGln: 0.681 ± 0.023
1.294TrpArg: 1.294 ± 0.035
1.208TrpSer: 1.208 ± 0.031
1.027TrpThr: 1.027 ± 0.029
1.266TrpVal: 1.266 ± 0.028
0.404TrpTrp: 0.404 ± 0.02
0.321TrpTyr: 0.321 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.828TyrAla: 2.828 ± 0.047
0.148TyrCys: 0.148 ± 0.01
1.832TyrAsp: 1.832 ± 0.039
1.088TyrGlu: 1.088 ± 0.027
0.668TyrPhe: 0.668 ± 0.019
2.026TyrGly: 2.026 ± 0.041
0.335TyrHis: 0.335 ± 0.017
0.599TyrIle: 0.599 ± 0.019
0.399TyrLys: 0.399 ± 0.017
2.131TyrLeu: 2.131 ± 0.042
0.232TyrMet: 0.232 ± 0.011
0.443TyrAsn: 0.443 ± 0.019
1.05TyrPro: 1.05 ± 0.028
0.609TyrGln: 0.609 ± 0.022
1.546TyrArg: 1.546 ± 0.031
1.065TyrSer: 1.065 ± 0.027
1.106TyrThr: 1.106 ± 0.028
1.877TyrVal: 1.877 ± 0.038
0.356TyrTrp: 0.356 ± 0.015
0.5TyrTyr: 0.5 ± 0.02
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4674 proteins (1476537 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski