Amino acid dipepetide frequency for Cardinium endosymbiont cBtQ1 of Bemisia tabaci

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.355AlaAla: 6.355 ± 0.224
1.095AlaCys: 1.095 ± 0.058
3.132AlaAsp: 3.132 ± 0.115
3.285AlaGlu: 3.285 ± 0.133
3.232AlaPhe: 3.232 ± 0.119
4.007AlaGly: 4.007 ± 0.162
2.277AlaHis: 2.277 ± 0.113
7.5AlaIle: 7.5 ± 0.186
4.87AlaLys: 4.87 ± 0.149
8.994AlaLeu: 8.994 ± 0.219
1.979AlaMet: 1.979 ± 0.091
2.725AlaAsn: 2.725 ± 0.112
2.443AlaPro: 2.443 ± 0.114
3.14AlaGln: 3.14 ± 0.136
2.891AlaArg: 2.891 ± 0.122
4.389AlaSer: 4.389 ± 0.149
4.692AlaThr: 4.692 ± 0.143
4.816AlaVal: 4.816 ± 0.157
0.556AlaTrp: 0.556 ± 0.044
3.207AlaTyr: 3.207 ± 0.133
0.0AlaXaa: 0.0 ± 0.0
Cys
0.879CysAla: 0.879 ± 0.07
0.241CysCys: 0.241 ± 0.043
0.548CysAsp: 0.548 ± 0.045
0.398CysGlu: 0.398 ± 0.042
0.718CysPhe: 0.718 ± 0.058
0.635CysGly: 0.635 ± 0.057
0.386CysHis: 0.386 ± 0.041
1.253CysIle: 1.253 ± 0.078
1.041CysLys: 1.041 ± 0.076
1.41CysLeu: 1.41 ± 0.083
0.411CysMet: 0.411 ± 0.041
0.647CysAsn: 0.647 ± 0.06
0.44CysPro: 0.44 ± 0.047
0.452CysGln: 0.452 ± 0.045
0.423CysArg: 0.423 ± 0.039
1.025CysSer: 1.025 ± 0.074
0.85CysThr: 0.85 ± 0.059
0.61CysVal: 0.61 ± 0.069
0.158CysTrp: 0.158 ± 0.026
0.73CysTyr: 0.73 ± 0.056
0.0CysXaa: 0.0 ± 0.0
Asp
3.227AspAla: 3.227 ± 0.123
0.581AspCys: 0.581 ± 0.055
1.788AspAsp: 1.788 ± 0.099
2.165AspGlu: 2.165 ± 0.102
2.182AspPhe: 2.182 ± 0.102
2.949AspGly: 2.949 ± 0.127
1.506AspHis: 1.506 ± 0.079
3.597AspIle: 3.597 ± 0.138
3.505AspLys: 3.505 ± 0.142
5.31AspLeu: 5.31 ± 0.172
0.821AspMet: 0.821 ± 0.062
1.767AspAsn: 1.767 ± 0.098
2.294AspPro: 2.294 ± 0.1
2.352AspGln: 2.352 ± 0.109
2.248AspArg: 2.248 ± 0.109
2.232AspSer: 2.232 ± 0.103
2.514AspThr: 2.514 ± 0.102
2.356AspVal: 2.356 ± 0.107
0.519AspTrp: 0.519 ± 0.047
2.336AspTyr: 2.336 ± 0.115
0.0AspXaa: 0.0 ± 0.0
Glu
4.866GluAla: 4.866 ± 0.157
0.469GluCys: 0.469 ± 0.054
2.248GluAsp: 2.248 ± 0.109
3.8GluGlu: 3.8 ± 0.159
1.278GluPhe: 1.278 ± 0.079
3.144GluGly: 3.144 ± 0.13
1.108GluHis: 1.108 ± 0.066
4.107GluIle: 4.107 ± 0.143
5.277GluLys: 5.277 ± 0.168
4.638GluLeu: 4.638 ± 0.128
1.145GluMet: 1.145 ± 0.084
2.132GluAsn: 2.132 ± 0.097
1.626GluPro: 1.626 ± 0.096
2.647GluGln: 2.647 ± 0.099
2.501GluArg: 2.501 ± 0.125
2.605GluSer: 2.605 ± 0.109
2.813GluThr: 2.813 ± 0.103
3.667GluVal: 3.667 ± 0.142
0.485GluTrp: 0.485 ± 0.043
1.074GluTyr: 1.074 ± 0.064
0.0GluXaa: 0.0 ± 0.0
Phe
2.501PheAla: 2.501 ± 0.124
0.726PheCys: 0.726 ± 0.05
2.087PheAsp: 2.087 ± 0.109
1.904PheGlu: 1.904 ± 0.087
2.555PhePhe: 2.555 ± 0.123
2.377PheGly: 2.377 ± 0.111
1.008PheHis: 1.008 ± 0.069
3.858PheIle: 3.858 ± 0.153
2.887PheLys: 2.887 ± 0.122
4.841PheLeu: 4.841 ± 0.171
1.095PheMet: 1.095 ± 0.08
2.012PheAsn: 2.012 ± 0.085
1.813PhePro: 1.813 ± 0.094
1.618PheGln: 1.618 ± 0.087
1.8PheArg: 1.8 ± 0.088
3.261PheSer: 3.261 ± 0.122
2.389PheThr: 2.389 ± 0.098
2.448PheVal: 2.448 ± 0.108
0.531PheTrp: 0.531 ± 0.049
1.842PheTyr: 1.842 ± 0.103
0.0PheXaa: 0.0 ± 0.0
Gly
4.422GlyAla: 4.422 ± 0.196
0.987GlyCys: 0.987 ± 0.068
2.34GlyAsp: 2.34 ± 0.121
2.29GlyGlu: 2.29 ± 0.111
2.655GlyPhe: 2.655 ± 0.097
3.671GlyGly: 3.671 ± 0.155
1.784GlyHis: 1.784 ± 0.091
5.526GlyIle: 5.526 ± 0.164
5.057GlyLys: 5.057 ± 0.143
6.538GlyLeu: 6.538 ± 0.178
1.722GlyMet: 1.722 ± 0.087
2.406GlyAsn: 2.406 ± 0.108
1.809GlyPro: 1.809 ± 0.102
2.033GlyGln: 2.033 ± 0.105
2.514GlyArg: 2.514 ± 0.111
3.825GlySer: 3.825 ± 0.137
3.252GlyThr: 3.252 ± 0.122
3.514GlyVal: 3.514 ± 0.124
0.734GlyTrp: 0.734 ± 0.057
2.837GlyTyr: 2.837 ± 0.112
0.0GlyXaa: 0.0 ± 0.0
His
1.883HisAla: 1.883 ± 0.093
0.485HisCys: 0.485 ± 0.047
0.884HisAsp: 0.884 ± 0.06
0.958HisGlu: 0.958 ± 0.064
1.369HisPhe: 1.369 ± 0.083
1.46HisGly: 1.46 ± 0.077
0.975HisHis: 0.975 ± 0.06
2.286HisIle: 2.286 ± 0.116
1.78HisLys: 1.78 ± 0.079
3.543HisLeu: 3.543 ± 0.146
0.585HisMet: 0.585 ± 0.05
1.186HisAsn: 1.186 ± 0.079
1.456HisPro: 1.456 ± 0.087
1.34HisGln: 1.34 ± 0.078
1.095HisArg: 1.095 ± 0.071
1.56HisSer: 1.56 ± 0.081
1.755HisThr: 1.755 ± 0.084
1.39HisVal: 1.39 ± 0.072
0.311HisTrp: 0.311 ± 0.04
1.41HisTyr: 1.41 ± 0.088
0.0HisXaa: 0.0 ± 0.0
Ile
7.318IleAla: 7.318 ± 0.204
1.207IleCys: 1.207 ± 0.067
4.825IleAsp: 4.825 ± 0.144
5.065IleGlu: 5.065 ± 0.151
3.256IlePhe: 3.256 ± 0.147
5.463IleGly: 5.463 ± 0.166
2.141IleHis: 2.141 ± 0.083
5.687IleIle: 5.687 ± 0.17
6.086IleLys: 6.086 ± 0.146
7.658IleLeu: 7.658 ± 0.209
1.576IleMet: 1.576 ± 0.093
3.244IleAsn: 3.244 ± 0.134
3.572IlePro: 3.572 ± 0.111
4.157IleGln: 4.157 ± 0.143
3.186IleArg: 3.186 ± 0.126
4.713IleSer: 4.713 ± 0.16
4.829IleThr: 4.829 ± 0.145
5.111IleVal: 5.111 ± 0.174
0.842IleTrp: 0.842 ± 0.057
2.896IleTyr: 2.896 ± 0.113
0.0IleXaa: 0.0 ± 0.0
Lys
5.252LysAla: 5.252 ± 0.179
0.647LysCys: 0.647 ± 0.057
3.493LysAsp: 3.493 ± 0.134
5.285LysGlu: 5.285 ± 0.172
2.12LysPhe: 2.12 ± 0.087
4.505LysGly: 4.505 ± 0.148
1.531LysHis: 1.531 ± 0.08
5.986LysIle: 5.986 ± 0.154
7.148LysLys: 7.148 ± 0.206
6.745LysLeu: 6.745 ± 0.201
1.713LysMet: 1.713 ± 0.086
4.032LysAsn: 4.032 ± 0.155
2.506LysPro: 2.506 ± 0.101
3.373LysGln: 3.373 ± 0.139
3.568LysArg: 3.568 ± 0.157
3.958LysSer: 3.958 ± 0.151
3.837LysThr: 3.837 ± 0.128
4.912LysVal: 4.912 ± 0.147
0.826LysTrp: 0.826 ± 0.05
2.423LysTyr: 2.423 ± 0.098
0.0LysXaa: 0.0 ± 0.0
Leu
8.326LeuAla: 8.326 ± 0.201
1.543LeuCys: 1.543 ± 0.089
5.148LeuAsp: 5.148 ± 0.144
5.75LeuGlu: 5.75 ± 0.184
5.098LeuPhe: 5.098 ± 0.181
5.841LeuGly: 5.841 ± 0.195
3.447LeuHis: 3.447 ± 0.152
7.658LeuIle: 7.658 ± 0.231
7.11LeuLys: 7.11 ± 0.2
12.798LeuLeu: 12.798 ± 0.289
2.622LeuMet: 2.622 ± 0.129
4.551LeuAsn: 4.551 ± 0.148
4.883LeuPro: 4.883 ± 0.152
4.713LeuGln: 4.713 ± 0.147
3.916LeuArg: 3.916 ± 0.119
7.645LeuSer: 7.645 ± 0.197
5.77LeuThr: 5.77 ± 0.155
6.633LeuVal: 6.633 ± 0.2
0.95LeuTrp: 0.95 ± 0.063
3.949LeuTyr: 3.949 ± 0.159
0.0LeuXaa: 0.0 ± 0.0
Met
2.439MetAla: 2.439 ± 0.114
0.224MetCys: 0.224 ± 0.028
1.344MetAsp: 1.344 ± 0.077
1.452MetGlu: 1.452 ± 0.072
0.585MetPhe: 0.585 ± 0.052
1.572MetGly: 1.572 ± 0.091
0.838MetHis: 0.838 ± 0.064
1.481MetIle: 1.481 ± 0.096
1.269MetLys: 1.269 ± 0.072
2.369MetLeu: 2.369 ± 0.113
0.548MetMet: 0.548 ± 0.046
0.863MetAsn: 0.863 ± 0.061
1.016MetPro: 1.016 ± 0.064
1.166MetGln: 1.166 ± 0.063
1.012MetArg: 1.012 ± 0.069
1.087MetSer: 1.087 ± 0.071
0.863MetThr: 0.863 ± 0.067
2.298MetVal: 2.298 ± 0.103
0.17MetTrp: 0.17 ± 0.028
0.655MetTyr: 0.655 ± 0.053
0.0MetXaa: 0.0 ± 0.0
Asn
2.659AsnAla: 2.659 ± 0.109
0.452AsnCys: 0.452 ± 0.044
1.912AsnAsp: 1.912 ± 0.098
1.846AsnGlu: 1.846 ± 0.102
2.149AsnPhe: 2.149 ± 0.111
3.111AsnGly: 3.111 ± 0.11
1.514AsnHis: 1.514 ± 0.087
3.792AsnIle: 3.792 ± 0.138
3.443AsnLys: 3.443 ± 0.138
4.654AsnLeu: 4.654 ± 0.154
0.921AsnMet: 0.921 ± 0.061
2.016AsnAsn: 2.016 ± 0.122
1.937AsnPro: 1.937 ± 0.092
2.182AsnGln: 2.182 ± 0.092
2.248AsnArg: 2.248 ± 0.101
2.186AsnSer: 2.186 ± 0.096
2.099AsnThr: 2.099 ± 0.103
2.17AsnVal: 2.17 ± 0.099
0.465AsnTrp: 0.465 ± 0.04
1.51AsnTyr: 1.51 ± 0.09
0.0AsnXaa: 0.0 ± 0.0
Pro
2.36ProAla: 2.36 ± 0.114
0.469ProCys: 0.469 ± 0.044
1.792ProAsp: 1.792 ± 0.094
1.975ProGlu: 1.975 ± 0.096
2.112ProPhe: 2.112 ± 0.092
1.958ProGly: 1.958 ± 0.096
0.991ProHis: 0.991 ± 0.071
4.128ProIle: 4.128 ± 0.143
2.53ProLys: 2.53 ± 0.106
4.866ProLeu: 4.866 ± 0.151
0.958ProMet: 0.958 ± 0.074
1.97ProAsn: 1.97 ± 0.093
1.423ProPro: 1.423 ± 0.103
1.137ProGln: 1.137 ± 0.085
1.07ProArg: 1.07 ± 0.075
2.97ProSer: 2.97 ± 0.131
2.738ProThr: 2.738 ± 0.107
2.132ProVal: 2.132 ± 0.108
0.369ProTrp: 0.369 ± 0.043
1.821ProTyr: 1.821 ± 0.091
0.0ProXaa: 0.0 ± 0.0
Gln
3.348GlnAla: 3.348 ± 0.13
0.373GlnCys: 0.373 ± 0.038
1.854GlnAsp: 1.854 ± 0.09
2.688GlnGlu: 2.688 ± 0.114
1.601GlnPhe: 1.601 ± 0.094
2.348GlnGly: 2.348 ± 0.113
1.025GlnHis: 1.025 ± 0.071
2.912GlnIle: 2.912 ± 0.115
3.576GlnLys: 3.576 ± 0.127
4.812GlnLeu: 4.812 ± 0.159
1.029GlnMet: 1.029 ± 0.075
1.917GlnAsn: 1.917 ± 0.091
1.746GlnPro: 1.746 ± 0.091
2.282GlnGln: 2.282 ± 0.117
1.958GlnArg: 1.958 ± 0.095
2.514GlnSer: 2.514 ± 0.105
2.178GlnThr: 2.178 ± 0.101
2.713GlnVal: 2.713 ± 0.122
0.373GlnTrp: 0.373 ± 0.041
1.406GlnTyr: 1.406 ± 0.087
0.0GlnXaa: 0.0 ± 0.0
Arg
2.767ArgAla: 2.767 ± 0.123
0.523ArgCys: 0.523 ± 0.047
1.634ArgAsp: 1.634 ± 0.101
1.763ArgGlu: 1.763 ± 0.093
2.099ArgPhe: 2.099 ± 0.092
2.082ArgGly: 2.082 ± 0.109
1.025ArgHis: 1.025 ± 0.056
3.157ArgIle: 3.157 ± 0.121
3.269ArgLys: 3.269 ± 0.144
4.932ArgLeu: 4.932 ± 0.163
1.054ArgMet: 1.054 ± 0.061
1.858ArgAsn: 1.858 ± 0.092
1.605ArgPro: 1.605 ± 0.091
1.473ArgGln: 1.473 ± 0.086
1.63ArgArg: 1.63 ± 0.093
2.813ArgSer: 2.813 ± 0.123
2.493ArgThr: 2.493 ± 0.121
2.265ArgVal: 2.265 ± 0.104
0.481ArgTrp: 0.481 ± 0.042
1.809ArgTyr: 1.809 ± 0.097
0.0ArgXaa: 0.0 ± 0.0
Ser
3.613SerAla: 3.613 ± 0.138
0.946SerCys: 0.946 ± 0.081
2.713SerAsp: 2.713 ± 0.117
2.725SerGlu: 2.725 ± 0.101
3.037SerPhe: 3.037 ± 0.127
3.746SerGly: 3.746 ± 0.154
1.522SerHis: 1.522 ± 0.08
6.052SerIle: 6.052 ± 0.179
4.244SerLys: 4.244 ± 0.158
6.583SerLeu: 6.583 ± 0.179
1.439SerMet: 1.439 ± 0.076
2.962SerAsn: 2.962 ± 0.11
2.045SerPro: 2.045 ± 0.103
1.821SerGln: 1.821 ± 0.09
2.253SerArg: 2.253 ± 0.096
4.086SerSer: 4.086 ± 0.159
3.671SerThr: 3.671 ± 0.134
3.588SerVal: 3.588 ± 0.109
0.543SerTrp: 0.543 ± 0.048
2.555SerTyr: 2.555 ± 0.1
0.0SerXaa: 0.0 ± 0.0
Thr
4.451ThrAla: 4.451 ± 0.148
0.676ThrCys: 0.676 ± 0.053
2.688ThrAsp: 2.688 ± 0.115
2.613ThrGlu: 2.613 ± 0.102
2.862ThrPhe: 2.862 ± 0.114
3.787ThrGly: 3.787 ± 0.15
1.626ThrHis: 1.626 ± 0.079
5.75ThrIle: 5.75 ± 0.184
3.75ThrLys: 3.75 ± 0.13
6.322ThrLeu: 6.322 ± 0.183
1.211ThrMet: 1.211 ± 0.068
2.182ThrAsn: 2.182 ± 0.106
2.9ThrPro: 2.9 ± 0.147
2.041ThrGln: 2.041 ± 0.094
1.975ThrArg: 1.975 ± 0.098
2.995ThrSer: 2.995 ± 0.132
4.202ThrThr: 4.202 ± 0.17
3.294ThrVal: 3.294 ± 0.12
0.377ThrTrp: 0.377 ± 0.033
2.0ThrTyr: 2.0 ± 0.092
0.0ThrXaa: 0.0 ± 0.0
Val
5.542ValAla: 5.542 ± 0.167
0.892ValCys: 0.892 ± 0.07
3.563ValAsp: 3.563 ± 0.129
3.563ValGlu: 3.563 ± 0.133
2.244ValPhe: 2.244 ± 0.122
4.024ValGly: 4.024 ± 0.13
1.489ValHis: 1.489 ± 0.081
4.314ValIle: 4.314 ± 0.139
3.775ValLys: 3.775 ± 0.139
6.007ValLeu: 6.007 ± 0.159
1.228ValMet: 1.228 ± 0.079
2.435ValAsn: 2.435 ± 0.117
2.323ValPro: 2.323 ± 0.105
2.618ValGln: 2.618 ± 0.119
2.273ValArg: 2.273 ± 0.101
3.646ValSer: 3.646 ± 0.133
3.696ValThr: 3.696 ± 0.129
4.92ValVal: 4.92 ± 0.186
0.56ValTrp: 0.56 ± 0.045
2.058ValTyr: 2.058 ± 0.084
0.0ValXaa: 0.0 ± 0.0
Trp
0.639TrpAla: 0.639 ± 0.047
0.153TrpCys: 0.153 ± 0.023
0.548TrpAsp: 0.548 ± 0.048
0.494TrpGlu: 0.494 ± 0.043
0.502TrpPhe: 0.502 ± 0.048
0.527TrpGly: 0.527 ± 0.047
0.353TrpHis: 0.353 ± 0.035
0.821TrpIle: 0.821 ± 0.059
0.56TrpLys: 0.56 ± 0.053
1.315TrpLeu: 1.315 ± 0.099
0.286TrpMet: 0.286 ± 0.033
0.419TrpAsn: 0.419 ± 0.046
0.332TrpPro: 0.332 ± 0.041
0.386TrpGln: 0.386 ± 0.04
0.382TrpArg: 0.382 ± 0.044
0.568TrpSer: 0.568 ± 0.05
0.456TrpThr: 0.456 ± 0.045
0.539TrpVal: 0.539 ± 0.05
0.137TrpTrp: 0.137 ± 0.024
0.394TrpTyr: 0.394 ± 0.037
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.738TyrAla: 2.738 ± 0.105
0.564TyrCys: 0.564 ± 0.05
1.709TyrAsp: 1.709 ± 0.093
1.61TyrGlu: 1.61 ± 0.098
1.9TyrPhe: 1.9 ± 0.105
2.705TyrGly: 2.705 ± 0.107
1.166TyrHis: 1.166 ± 0.076
2.97TyrIle: 2.97 ± 0.124
2.68TyrLys: 2.68 ± 0.11
4.016TyrLeu: 4.016 ± 0.155
0.904TyrMet: 0.904 ± 0.059
1.941TyrAsn: 1.941 ± 0.099
1.601TyrPro: 1.601 ± 0.087
1.726TyrGln: 1.726 ± 0.106
1.788TyrArg: 1.788 ± 0.102
2.07TyrSer: 2.07 ± 0.102
2.605TyrThr: 2.605 ± 0.1
1.796TyrVal: 1.796 ± 0.083
0.423TyrTrp: 0.423 ± 0.043
1.643TyrTyr: 1.643 ± 0.101
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 694 proteins (241061 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski