Amino acid dipepetide frequency for Beihai tombus-like virus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.79AlaAla: 4.79 ± 2.622
0.599AlaCys: 0.599 ± 0.951
4.192AlaAsp: 4.192 ± 2.64
3.593AlaGlu: 3.593 ± 0.634
4.79AlaPhe: 4.79 ± 1.49
5.389AlaGly: 5.389 ± 2.471
2.994AlaHis: 2.994 ± 1.639
0.599AlaIle: 0.599 ± 0.328
5.988AlaLys: 5.988 ± 2.34
5.389AlaLeu: 5.389 ± 1.675
1.198AlaMet: 1.198 ± 0.899
2.395AlaAsn: 2.395 ± 0.883
3.593AlaPro: 3.593 ± 1.465
2.994AlaGln: 2.994 ± 1.269
4.79AlaArg: 4.79 ± 1.49
5.389AlaSer: 5.389 ± 2.397
8.982AlaThr: 8.982 ± 2.876
4.192AlaVal: 4.192 ± 2.018
1.198AlaTrp: 1.198 ± 0.899
2.395AlaTyr: 2.395 ± 1.311
0.0AlaXaa: 0.0 ± 0.0
Cys
1.796CysAla: 1.796 ± 0.799
1.198CysCys: 1.198 ± 0.757
0.0CysAsp: 0.0 ± 0.0
0.599CysGlu: 0.599 ± 0.328
0.0CysPhe: 0.0 ± 0.0
0.599CysGly: 0.599 ± 0.328
1.198CysHis: 1.198 ± 0.656
1.198CysIle: 1.198 ± 2.183
0.599CysLys: 0.599 ± 0.328
1.198CysLeu: 1.198 ± 0.656
0.0CysMet: 0.0 ± 0.0
0.599CysAsn: 0.599 ± 0.328
2.395CysPro: 2.395 ± 1.279
0.0CysGln: 0.0 ± 0.0
2.395CysArg: 2.395 ± 0.95
0.599CysSer: 0.599 ± 0.328
0.599CysThr: 0.599 ± 0.328
1.198CysVal: 1.198 ± 0.656
0.0CysTrp: 0.0 ± 0.0
0.599CysTyr: 0.599 ± 0.951
0.0CysXaa: 0.0 ± 0.0
Asp
5.389AspAla: 5.389 ± 1.776
0.0AspCys: 0.0 ± 0.0
1.796AspAsp: 1.796 ± 1.145
2.994AspGlu: 2.994 ± 1.639
1.198AspPhe: 1.198 ± 0.656
4.192AspGly: 4.192 ± 0.685
0.599AspHis: 0.599 ± 0.328
2.395AspIle: 2.395 ± 1.311
4.192AspLys: 4.192 ± 1.157
4.192AspLeu: 4.192 ± 1.432
0.599AspMet: 0.599 ± 0.811
0.599AspAsn: 0.599 ± 0.951
1.198AspPro: 1.198 ± 0.656
2.994AspGln: 2.994 ± 1.576
1.198AspArg: 1.198 ± 0.805
4.192AspSer: 4.192 ± 2.342
1.796AspThr: 1.796 ± 0.983
5.389AspVal: 5.389 ± 1.492
0.599AspTrp: 0.599 ± 0.328
1.796AspTyr: 1.796 ± 0.778
0.0AspXaa: 0.0 ± 0.0
Glu
5.988GluAla: 5.988 ± 0.716
0.0GluCys: 0.0 ± 0.0
2.994GluAsp: 2.994 ± 1.565
2.395GluGlu: 2.395 ± 1.024
1.796GluPhe: 1.796 ± 0.778
2.395GluGly: 2.395 ± 1.311
1.796GluHis: 1.796 ± 0.778
1.198GluIle: 1.198 ± 0.805
1.198GluLys: 1.198 ± 0.805
3.593GluLeu: 3.593 ± 1.465
1.796GluMet: 1.796 ± 0.839
1.796GluAsn: 1.796 ± 1.535
5.988GluPro: 5.988 ± 1.337
1.198GluGln: 1.198 ± 0.656
2.994GluArg: 2.994 ± 1.08
1.198GluSer: 1.198 ± 0.656
0.599GluThr: 0.599 ± 0.328
5.988GluVal: 5.988 ± 2.538
0.0GluTrp: 0.0 ± 0.0
1.796GluTyr: 1.796 ± 0.778
0.0GluXaa: 0.0 ± 0.0
Phe
1.198PheAla: 1.198 ± 0.899
0.599PheCys: 0.599 ± 0.328
0.0PheAsp: 0.0 ± 0.0
1.198PheGlu: 1.198 ± 0.656
1.198PhePhe: 1.198 ± 1.435
1.796PheGly: 1.796 ± 0.778
0.599PheHis: 0.599 ± 0.328
1.198PheIle: 1.198 ± 0.805
3.593PheLys: 3.593 ± 1.33
2.994PheLeu: 2.994 ± 0.955
2.395PheMet: 2.395 ± 0.883
2.994PheAsn: 2.994 ± 1.576
0.599PhePro: 0.599 ± 0.328
1.796PheGln: 1.796 ± 0.839
2.994PheArg: 2.994 ± 0.955
1.198PheSer: 1.198 ± 0.805
1.796PheThr: 1.796 ± 0.799
4.192PheVal: 4.192 ± 2.342
0.0PheTrp: 0.0 ± 0.0
0.599PheTyr: 0.599 ± 0.328
0.0PheXaa: 0.0 ± 0.0
Gly
4.79GlyAla: 4.79 ± 2.913
0.599GlyCys: 0.599 ± 0.328
4.192GlyAsp: 4.192 ± 0.685
3.593GlyGlu: 3.593 ± 1.49
1.198GlyPhe: 1.198 ± 0.656
2.395GlyGly: 2.395 ± 0.827
1.198GlyHis: 1.198 ± 0.899
3.593GlyIle: 3.593 ± 1.33
5.988GlyLys: 5.988 ± 1.803
3.593GlyLeu: 3.593 ± 2.272
1.796GlyMet: 1.796 ± 2.324
1.796GlyAsn: 1.796 ± 0.983
3.593GlyPro: 3.593 ± 0.598
2.395GlyGln: 2.395 ± 1.024
7.186GlyArg: 7.186 ± 10.7
5.389GlySer: 5.389 ± 1.157
4.192GlyThr: 4.192 ± 0.685
4.79GlyVal: 4.79 ± 1.903
0.599GlyTrp: 0.599 ± 0.951
2.395GlyTyr: 2.395 ± 1.311
0.0GlyXaa: 0.0 ± 0.0
His
1.198HisAla: 1.198 ± 0.656
0.0HisCys: 0.0 ± 0.0
1.796HisAsp: 1.796 ± 0.778
1.198HisGlu: 1.198 ± 1.356
1.198HisPhe: 1.198 ± 0.656
1.198HisGly: 1.198 ± 0.656
0.0HisHis: 0.0 ± 0.0
0.599HisIle: 0.599 ± 1.091
2.994HisLys: 2.994 ± 1.639
2.994HisLeu: 2.994 ± 1.639
0.0HisMet: 0.0 ± 0.0
0.599HisAsn: 0.599 ± 0.328
1.796HisPro: 1.796 ± 0.983
2.395HisGln: 2.395 ± 0.865
1.796HisArg: 1.796 ± 0.983
5.988HisSer: 5.988 ± 2.236
1.198HisThr: 1.198 ± 0.899
1.796HisVal: 1.796 ± 0.799
0.0HisTrp: 0.0 ± 0.0
1.796HisTyr: 1.796 ± 0.799
0.0HisXaa: 0.0 ± 0.0
Ile
2.395IleAla: 2.395 ± 0.95
0.599IleCys: 0.599 ± 1.091
2.994IleAsp: 2.994 ± 1.549
1.796IleGlu: 1.796 ± 0.983
0.599IlePhe: 0.599 ± 0.328
2.994IleGly: 2.994 ± 1.669
1.796IleHis: 1.796 ± 2.366
2.395IleIle: 2.395 ± 1.797
2.994IleLys: 2.994 ± 1.639
4.192IleLeu: 4.192 ± 1.389
1.198IleMet: 1.198 ± 0.656
4.192IleAsn: 4.192 ± 1.432
2.994IlePro: 2.994 ± 1.867
1.796IleGln: 1.796 ± 0.839
1.796IleArg: 1.796 ± 0.799
3.593IleSer: 3.593 ± 0.598
1.796IleThr: 1.796 ± 0.778
2.994IleVal: 2.994 ± 1.549
0.0IleTrp: 0.0 ± 0.0
1.198IleTyr: 1.198 ± 1.901
0.0IleXaa: 0.0 ± 0.0
Lys
4.79LysAla: 4.79 ± 2.14
1.198LysCys: 1.198 ± 0.899
2.395LysAsp: 2.395 ± 1.311
2.395LysGlu: 2.395 ± 2.335
2.395LysPhe: 2.395 ± 0.95
7.186LysGly: 7.186 ± 2.291
2.994LysHis: 2.994 ± 1.639
3.593LysIle: 3.593 ± 2.546
5.389LysLys: 5.389 ± 2.449
7.186LysLeu: 7.186 ± 3.089
3.593LysMet: 3.593 ± 1.544
0.599LysAsn: 0.599 ± 0.328
3.593LysPro: 3.593 ± 1.33
1.198LysGln: 1.198 ± 0.656
4.79LysArg: 4.79 ± 1.737
2.994LysSer: 2.994 ± 1.639
5.389LysThr: 5.389 ± 2.023
3.593LysVal: 3.593 ± 0.598
0.599LysTrp: 0.599 ± 0.951
2.994LysTyr: 2.994 ± 0.679
0.0LysXaa: 0.0 ± 0.0
Leu
4.79LeuAla: 4.79 ± 1.269
2.994LeuCys: 2.994 ± 0.972
5.988LeuAsp: 5.988 ± 1.758
3.593LeuGlu: 3.593 ± 1.557
1.796LeuPhe: 1.796 ± 0.778
2.994LeuGly: 2.994 ± 1.08
2.395LeuHis: 2.395 ± 0.827
3.593LeuIle: 3.593 ± 1.192
9.581LeuLys: 9.581 ± 3.77
5.389LeuLeu: 5.389 ± 0.403
0.599LeuMet: 0.599 ± 0.811
2.994LeuAsn: 2.994 ± 0.955
1.796LeuPro: 1.796 ± 0.983
4.79LeuGln: 4.79 ± 3.447
2.994LeuArg: 2.994 ± 1.565
4.192LeuSer: 4.192 ± 2.14
4.192LeuThr: 4.192 ± 1.432
5.389LeuVal: 5.389 ± 0.403
1.198LeuTrp: 1.198 ± 0.656
2.994LeuTyr: 2.994 ± 1.269
0.0LeuXaa: 0.0 ± 0.0
Met
2.395MetAla: 2.395 ± 2.1
1.198MetCys: 1.198 ± 0.899
0.599MetAsp: 0.599 ± 0.328
2.395MetGlu: 2.395 ± 1.515
0.599MetPhe: 0.599 ± 0.811
1.796MetGly: 1.796 ± 1.972
1.198MetHis: 1.198 ± 0.805
0.599MetIle: 0.599 ± 0.328
1.796MetLys: 1.796 ± 0.778
2.395MetLeu: 2.395 ± 0.827
2.395MetMet: 2.395 ± 0.95
1.198MetAsn: 1.198 ± 2.183
1.198MetPro: 1.198 ± 0.656
1.796MetGln: 1.796 ± 1.535
2.994MetArg: 2.994 ± 0.855
3.593MetSer: 3.593 ± 1.192
1.796MetThr: 1.796 ± 1.145
1.796MetVal: 1.796 ± 0.778
0.599MetTrp: 0.599 ± 0.951
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.395AsnAla: 2.395 ± 1.279
0.599AsnCys: 0.599 ± 0.328
2.395AsnAsp: 2.395 ± 1.311
1.796AsnGlu: 1.796 ± 0.799
0.0AsnPhe: 0.0 ± 0.0
3.593AsnGly: 3.593 ± 1.557
1.198AsnHis: 1.198 ± 0.899
2.395AsnIle: 2.395 ± 0.95
2.395AsnLys: 2.395 ± 0.883
1.198AsnLeu: 1.198 ± 0.757
0.0AsnMet: 0.0 ± 0.0
0.599AsnAsn: 0.599 ± 0.811
1.198AsnPro: 1.198 ± 1.356
1.796AsnGln: 1.796 ± 1.535
2.395AsnArg: 2.395 ± 1.279
1.198AsnSer: 1.198 ± 0.757
5.389AsnThr: 5.389 ± 1.997
2.395AsnVal: 2.395 ± 1.903
0.0AsnTrp: 0.0 ± 0.0
2.994AsnTyr: 2.994 ± 0.679
0.0AsnXaa: 0.0 ± 0.0
Pro
3.593ProAla: 3.593 ± 1.33
0.599ProCys: 0.599 ± 0.328
2.994ProAsp: 2.994 ± 1.549
5.988ProGlu: 5.988 ± 1.211
2.395ProPhe: 2.395 ± 0.882
5.988ProGly: 5.988 ± 0.919
2.395ProHis: 2.395 ± 1.515
2.994ProIle: 2.994 ± 1.565
2.395ProLys: 2.395 ± 0.883
4.192ProLeu: 4.192 ± 1.415
0.0ProMet: 0.0 ± 0.0
2.994ProAsn: 2.994 ± 0.955
8.982ProPro: 8.982 ± 7.316
6.587ProGln: 6.587 ± 4.052
4.79ProArg: 4.79 ± 1.269
3.593ProSer: 3.593 ± 0.909
5.389ProThr: 5.389 ± 1.492
2.395ProVal: 2.395 ± 1.024
0.599ProTrp: 0.599 ± 0.328
0.599ProTyr: 0.599 ± 0.951
0.0ProXaa: 0.0 ± 0.0
Gln
2.994GlnAla: 2.994 ± 1.669
1.198GlnCys: 1.198 ± 0.757
0.599GlnAsp: 0.599 ± 0.328
0.599GlnGlu: 0.599 ± 0.811
1.198GlnPhe: 1.198 ± 0.656
2.395GlnGly: 2.395 ± 1.743
0.599GlnHis: 0.599 ± 0.328
2.395GlnIle: 2.395 ± 0.95
0.599GlnLys: 0.599 ± 0.328
6.587GlnLeu: 6.587 ± 2.569
2.994GlnMet: 2.994 ± 2.263
1.198GlnAsn: 1.198 ± 1.196
7.784GlnPro: 7.784 ± 2.869
2.395GlnGln: 2.395 ± 1.024
1.198GlnArg: 1.198 ± 0.656
3.593GlnSer: 3.593 ± 1.413
2.395GlnThr: 2.395 ± 1.797
3.593GlnVal: 3.593 ± 1.413
0.599GlnTrp: 0.599 ± 0.951
1.198GlnTyr: 1.198 ± 0.656
0.0GlnXaa: 0.0 ± 0.0
Arg
4.79ArgAla: 4.79 ± 1.655
1.796ArgCys: 1.796 ± 0.839
1.198ArgAsp: 1.198 ± 1.901
1.796ArgGlu: 1.796 ± 0.839
2.395ArgPhe: 2.395 ± 0.95
4.79ArgGly: 4.79 ± 7.418
4.192ArgHis: 4.192 ± 1.632
1.796ArgIle: 1.796 ± 0.778
6.587ArgLys: 6.587 ± 2.863
3.593ArgLeu: 3.593 ± 2.272
4.79ArgMet: 4.79 ± 2.457
2.994ArgAsn: 2.994 ± 0.679
2.994ArgPro: 2.994 ± 0.679
4.79ArgGln: 4.79 ± 1.49
4.79ArgArg: 4.79 ± 2.948
1.796ArgSer: 1.796 ± 0.839
2.994ArgThr: 2.994 ± 1.639
3.593ArgVal: 3.593 ± 1.33
0.599ArgTrp: 0.599 ± 0.328
1.796ArgTyr: 1.796 ± 0.799
0.0ArgXaa: 0.0 ± 0.0
Ser
6.587SerAla: 6.587 ± 1.038
0.599SerCys: 0.599 ± 0.328
2.994SerAsp: 2.994 ± 0.972
2.994SerGlu: 2.994 ± 1.639
1.796SerPhe: 1.796 ± 0.778
4.192SerGly: 4.192 ± 1.453
1.198SerHis: 1.198 ± 0.899
4.79SerIle: 4.79 ± 1.151
4.192SerLys: 4.192 ± 1.593
4.192SerLeu: 4.192 ± 2.348
0.0SerMet: 0.0 ± 0.0
1.796SerAsn: 1.796 ± 0.983
6.587SerPro: 6.587 ± 2.19
1.796SerGln: 1.796 ± 0.839
5.988SerArg: 5.988 ± 2.538
4.79SerSer: 4.79 ± 0.892
5.988SerThr: 5.988 ± 1.447
4.192SerVal: 4.192 ± 2.018
0.599SerTrp: 0.599 ± 0.951
1.198SerTyr: 1.198 ± 1.435
0.0SerXaa: 0.0 ± 0.0
Thr
7.784ThrAla: 7.784 ± 3.455
1.198ThrCys: 1.198 ± 0.899
2.395ThrAsp: 2.395 ± 1.311
2.994ThrGlu: 2.994 ± 1.08
4.192ThrPhe: 4.192 ± 2.994
5.389ThrGly: 5.389 ± 2.239
1.198ThrHis: 1.198 ± 0.656
4.192ThrIle: 4.192 ± 3.185
1.796ThrLys: 1.796 ± 0.991
2.994ThrLeu: 2.994 ± 0.87
2.994ThrMet: 2.994 ± 1.259
0.599ThrAsn: 0.599 ± 0.951
5.988ThrPro: 5.988 ± 2.34
2.395ThrGln: 2.395 ± 0.882
2.994ThrArg: 2.994 ± 1.269
5.389ThrSer: 5.389 ± 1.178
5.988ThrThr: 5.988 ± 3.161
4.192ThrVal: 4.192 ± 3.326
0.599ThrTrp: 0.599 ± 0.328
3.593ThrTyr: 3.593 ± 1.557
0.0ThrXaa: 0.0 ± 0.0
Val
5.389ValAla: 5.389 ± 3.141
0.599ValCys: 0.599 ± 0.951
4.79ValAsp: 4.79 ± 2.14
3.593ValGlu: 3.593 ± 0.963
2.994ValPhe: 2.994 ± 1.549
4.79ValGly: 4.79 ± 0.166
1.198ValHis: 1.198 ± 0.656
2.395ValIle: 2.395 ± 1.311
4.192ValLys: 4.192 ± 1.389
4.79ValLeu: 4.79 ± 1.151
2.994ValMet: 2.994 ± 1.598
2.994ValAsn: 2.994 ± 1.651
4.192ValPro: 4.192 ± 1.415
1.796ValGln: 1.796 ± 1.124
3.593ValArg: 3.593 ± 1.33
5.389ValSer: 5.389 ± 2.206
5.988ValThr: 5.988 ± 4.308
6.587ValVal: 6.587 ± 3.088
1.198ValTrp: 1.198 ± 0.757
1.796ValTyr: 1.796 ± 0.983
0.599ValXaa: 0.599 ± 0.328
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.599TrpAsp: 0.599 ± 0.328
0.0TrpGlu: 0.0 ± 0.0
0.599TrpPhe: 0.599 ± 0.328
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.599TrpIle: 0.599 ± 0.328
0.0TrpLys: 0.0 ± 0.0
1.198TrpLeu: 1.198 ± 1.901
0.599TrpMet: 0.599 ± 0.315
0.599TrpAsn: 0.599 ± 0.328
0.599TrpPro: 0.599 ± 0.951
0.599TrpGln: 0.599 ± 1.091
0.0TrpArg: 0.0 ± 0.0
0.599TrpSer: 0.599 ± 0.328
1.796TrpThr: 1.796 ± 1.731
1.796TrpVal: 1.796 ± 0.839
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.395TyrAla: 2.395 ± 1.311
1.198TyrCys: 1.198 ± 0.656
1.796TyrAsp: 1.796 ± 0.983
1.198TyrGlu: 1.198 ± 0.656
0.599TyrPhe: 0.599 ± 0.328
1.198TyrGly: 1.198 ± 0.656
1.796TyrHis: 1.796 ± 0.799
1.796TyrIle: 1.796 ± 1.145
2.395TyrLys: 2.395 ± 1.903
2.395TyrLeu: 2.395 ± 1.311
1.796TyrMet: 1.796 ± 1.731
2.395TyrAsn: 2.395 ± 1.797
2.395TyrPro: 2.395 ± 0.865
0.599TyrGln: 0.599 ± 0.328
2.395TyrArg: 2.395 ± 0.883
1.796TyrSer: 1.796 ± 0.778
1.198TyrThr: 1.198 ± 1.901
1.796TyrVal: 1.796 ± 0.778
0.599TyrTrp: 0.599 ± 0.328
0.599TyrTyr: 0.599 ± 0.328
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.599XaaAsp: 0.599 ± 0.328
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1671 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski