Amino acid dipepetide frequency for Lizard adenovirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.402AlaAla: 6.402 ± 1.247
1.763AlaCys: 1.763 ± 0.428
2.691AlaAsp: 2.691 ± 0.517
2.505AlaGlu: 2.505 ± 0.464
2.32AlaPhe: 2.32 ± 0.466
3.247AlaGly: 3.247 ± 0.613
0.742AlaHis: 0.742 ± 0.247
2.505AlaIle: 2.505 ± 0.607
2.691AlaLys: 2.691 ± 0.674
6.866AlaLeu: 6.866 ± 0.784
1.577AlaMet: 1.577 ± 0.37
2.691AlaAsn: 2.691 ± 0.634
5.474AlaPro: 5.474 ± 0.827
1.948AlaGln: 1.948 ± 0.415
4.361AlaArg: 4.361 ± 0.713
4.917AlaSer: 4.917 ± 0.513
3.711AlaThr: 3.711 ± 0.663
5.01AlaVal: 5.01 ± 1.007
0.464AlaTrp: 0.464 ± 0.21
1.856AlaTyr: 1.856 ± 0.38
0.0AlaXaa: 0.0 ± 0.0
Cys
0.928CysAla: 0.928 ± 0.4
0.928CysCys: 0.928 ± 0.36
0.835CysAsp: 0.835 ± 0.258
1.485CysGlu: 1.485 ± 0.367
1.392CysPhe: 1.392 ± 0.475
1.856CysGly: 1.856 ± 0.39
0.928CysHis: 0.928 ± 0.378
0.464CysIle: 0.464 ± 0.242
0.928CysLys: 0.928 ± 0.362
1.67CysLeu: 1.67 ± 0.593
0.557CysMet: 0.557 ± 0.244
1.577CysAsn: 1.577 ± 0.539
1.485CysPro: 1.485 ± 0.4
0.835CysGln: 0.835 ± 0.313
1.485CysArg: 1.485 ± 0.397
2.041CysSer: 2.041 ± 0.538
1.299CysThr: 1.299 ± 0.393
1.113CysVal: 1.113 ± 0.368
0.278CysTrp: 0.278 ± 0.186
0.928CysTyr: 0.928 ± 0.296
0.0CysXaa: 0.0 ± 0.0
Asp
2.691AspAla: 2.691 ± 0.43
1.206AspCys: 1.206 ± 0.438
1.856AspAsp: 1.856 ± 0.377
2.691AspGlu: 2.691 ± 0.779
2.783AspPhe: 2.783 ± 0.556
2.691AspGly: 2.691 ± 0.501
0.835AspHis: 0.835 ± 0.235
2.876AspIle: 2.876 ± 0.6
2.227AspLys: 2.227 ± 0.548
3.804AspLeu: 3.804 ± 0.546
1.021AspMet: 1.021 ± 0.35
1.948AspAsn: 1.948 ± 0.344
3.062AspPro: 3.062 ± 0.631
1.856AspGln: 1.856 ± 0.449
2.783AspArg: 2.783 ± 0.596
2.691AspSer: 2.691 ± 0.441
3.526AspThr: 3.526 ± 0.589
1.948AspVal: 1.948 ± 0.396
0.371AspTrp: 0.371 ± 0.171
2.134AspTyr: 2.134 ± 0.435
0.0AspXaa: 0.0 ± 0.0
Glu
4.082GluAla: 4.082 ± 0.856
1.485GluCys: 1.485 ± 0.426
3.526GluAsp: 3.526 ± 0.552
7.051GluGlu: 7.051 ± 1.524
1.021GluPhe: 1.021 ± 0.265
3.897GluGly: 3.897 ± 0.535
0.649GluHis: 0.649 ± 0.218
2.505GluIle: 2.505 ± 0.46
3.99GluLys: 3.99 ± 0.952
4.268GluLeu: 4.268 ± 0.604
1.021GluMet: 1.021 ± 0.443
3.618GluAsn: 3.618 ± 0.649
3.34GluPro: 3.34 ± 0.424
2.783GluGln: 2.783 ± 0.676
3.804GluArg: 3.804 ± 0.686
2.32GluSer: 2.32 ± 0.538
3.897GluThr: 3.897 ± 0.555
3.711GluVal: 3.711 ± 0.631
1.113GluTrp: 1.113 ± 0.335
1.485GluTyr: 1.485 ± 0.374
0.0GluXaa: 0.0 ± 0.0
Phe
2.505PheAla: 2.505 ± 0.473
1.485PheCys: 1.485 ± 0.395
2.041PheAsp: 2.041 ± 0.378
2.412PheGlu: 2.412 ± 0.359
2.876PhePhe: 2.876 ± 0.549
2.412PheGly: 2.412 ± 0.528
1.206PheHis: 1.206 ± 0.347
2.505PheIle: 2.505 ± 0.422
2.598PheLys: 2.598 ± 0.463
4.361PheLeu: 4.361 ± 0.63
1.299PheMet: 1.299 ± 0.386
2.876PheAsn: 2.876 ± 0.524
2.876PhePro: 2.876 ± 0.617
1.763PheGln: 1.763 ± 0.382
2.505PheArg: 2.505 ± 0.44
3.897PheSer: 3.897 ± 0.545
3.247PheThr: 3.247 ± 0.524
2.505PheVal: 2.505 ± 0.461
1.206PheTrp: 1.206 ± 0.384
1.485PheTyr: 1.485 ± 0.342
0.0PheXaa: 0.0 ± 0.0
Gly
4.361GlyAla: 4.361 ± 0.725
1.299GlyCys: 1.299 ± 0.495
2.691GlyAsp: 2.691 ± 0.503
4.082GlyGlu: 4.082 ± 0.581
2.598GlyPhe: 2.598 ± 0.526
4.361GlyGly: 4.361 ± 0.614
1.763GlyHis: 1.763 ± 0.474
1.763GlyIle: 1.763 ± 0.401
3.804GlyLys: 3.804 ± 0.918
4.268GlyLeu: 4.268 ± 0.873
1.299GlyMet: 1.299 ± 0.275
3.711GlyAsn: 3.711 ± 0.998
2.969GlyPro: 2.969 ± 0.513
2.041GlyGln: 2.041 ± 0.353
4.082GlyArg: 4.082 ± 0.433
6.402GlySer: 6.402 ± 1.035
3.618GlyThr: 3.618 ± 0.613
3.804GlyVal: 3.804 ± 0.759
1.021GlyTrp: 1.021 ± 0.235
2.505GlyTyr: 2.505 ± 0.426
0.0GlyXaa: 0.0 ± 0.0
His
1.392HisAla: 1.392 ± 0.414
1.392HisCys: 1.392 ± 0.422
0.557HisAsp: 0.557 ± 0.234
0.464HisGlu: 0.464 ± 0.191
0.742HisPhe: 0.742 ± 0.271
1.113HisGly: 1.113 ± 0.388
0.649HisHis: 0.649 ± 0.238
0.649HisIle: 0.649 ± 0.182
1.113HisLys: 1.113 ± 0.3
2.041HisLeu: 2.041 ± 0.487
0.278HisMet: 0.278 ± 0.17
0.928HisAsn: 0.928 ± 0.303
1.577HisPro: 1.577 ± 0.485
0.557HisGln: 0.557 ± 0.25
1.856HisArg: 1.856 ± 0.401
1.299HisSer: 1.299 ± 0.32
0.835HisThr: 0.835 ± 0.347
1.485HisVal: 1.485 ± 0.351
0.371HisTrp: 0.371 ± 0.269
0.835HisTyr: 0.835 ± 0.265
0.0HisXaa: 0.0 ± 0.0
Ile
2.691IleAla: 2.691 ± 0.45
1.113IleCys: 1.113 ± 0.322
2.32IleAsp: 2.32 ± 0.534
1.948IleGlu: 1.948 ± 0.444
1.392IlePhe: 1.392 ± 0.367
4.082IleGly: 4.082 ± 0.682
0.464IleHis: 0.464 ± 0.178
1.67IleIle: 1.67 ± 0.404
2.598IleLys: 2.598 ± 0.502
4.732IleLeu: 4.732 ± 0.771
0.835IleMet: 0.835 ± 0.214
2.134IleAsn: 2.134 ± 0.491
2.783IlePro: 2.783 ± 0.499
2.227IleGln: 2.227 ± 0.593
2.412IleArg: 2.412 ± 0.645
4.175IleSer: 4.175 ± 0.747
2.134IleThr: 2.134 ± 0.416
3.155IleVal: 3.155 ± 0.496
0.464IleTrp: 0.464 ± 0.166
1.577IleTyr: 1.577 ± 0.35
0.0IleXaa: 0.0 ± 0.0
Lys
3.34LysAla: 3.34 ± 0.463
1.021LysCys: 1.021 ± 0.371
2.969LysAsp: 2.969 ± 0.69
3.34LysGlu: 3.34 ± 0.606
1.763LysPhe: 1.763 ± 0.439
2.412LysGly: 2.412 ± 0.485
0.835LysHis: 0.835 ± 0.285
2.783LysIle: 2.783 ± 0.63
3.155LysLys: 3.155 ± 0.819
5.938LysLeu: 5.938 ± 0.884
0.742LysMet: 0.742 ± 0.447
3.711LysAsn: 3.711 ± 0.613
2.412LysPro: 2.412 ± 0.639
1.763LysGln: 1.763 ± 0.499
3.062LysArg: 3.062 ± 0.503
3.99LysSer: 3.99 ± 0.839
3.711LysThr: 3.711 ± 0.89
1.67LysVal: 1.67 ± 0.377
0.835LysTrp: 0.835 ± 0.293
1.763LysTyr: 1.763 ± 0.456
0.0LysXaa: 0.0 ± 0.0
Leu
6.402LeuAla: 6.402 ± 0.725
1.948LeuCys: 1.948 ± 0.538
3.804LeuAsp: 3.804 ± 0.633
5.66LeuGlu: 5.66 ± 0.757
3.711LeuPhe: 3.711 ± 0.742
6.495LeuGly: 6.495 ± 0.674
2.041LeuHis: 2.041 ± 0.418
3.897LeuIle: 3.897 ± 0.704
5.845LeuLys: 5.845 ± 0.782
9.278LeuLeu: 9.278 ± 0.962
2.041LeuMet: 2.041 ± 0.545
5.196LeuAsn: 5.196 ± 0.582
6.031LeuPro: 6.031 ± 0.553
5.289LeuGln: 5.289 ± 0.694
3.99LeuArg: 3.99 ± 0.633
7.979LeuSer: 7.979 ± 0.914
6.68LeuThr: 6.68 ± 0.928
5.66LeuVal: 5.66 ± 0.601
1.206LeuTrp: 1.206 ± 0.363
3.526LeuTyr: 3.526 ± 0.405
0.0LeuXaa: 0.0 ± 0.0
Met
1.763MetAla: 1.763 ± 0.258
0.278MetCys: 0.278 ± 0.199
0.835MetAsp: 0.835 ± 0.253
1.577MetGlu: 1.577 ± 0.382
1.299MetPhe: 1.299 ± 0.278
1.299MetGly: 1.299 ± 0.284
0.557MetHis: 0.557 ± 0.178
1.299MetIle: 1.299 ± 0.38
0.742MetLys: 0.742 ± 0.259
1.856MetLeu: 1.856 ± 0.423
0.464MetMet: 0.464 ± 0.229
0.835MetAsn: 0.835 ± 0.336
0.928MetPro: 0.928 ± 0.257
1.021MetGln: 1.021 ± 0.323
1.206MetArg: 1.206 ± 0.324
1.67MetSer: 1.67 ± 0.414
1.67MetThr: 1.67 ± 0.406
1.485MetVal: 1.485 ± 0.286
0.371MetTrp: 0.371 ± 0.167
0.649MetTyr: 0.649 ± 0.263
0.0MetXaa: 0.0 ± 0.0
Asn
2.412AsnAla: 2.412 ± 0.428
1.577AsnCys: 1.577 ± 0.451
2.041AsnAsp: 2.041 ± 0.582
2.32AsnGlu: 2.32 ± 0.415
3.618AsnPhe: 3.618 ± 0.577
2.505AsnGly: 2.505 ± 0.62
0.928AsnHis: 0.928 ± 0.315
2.969AsnIle: 2.969 ± 0.482
1.485AsnLys: 1.485 ± 0.452
6.216AsnLeu: 6.216 ± 0.722
1.577AsnMet: 1.577 ± 0.448
2.691AsnAsn: 2.691 ± 0.589
3.34AsnPro: 3.34 ± 0.513
2.505AsnGln: 2.505 ± 0.458
2.691AsnArg: 2.691 ± 0.56
3.711AsnSer: 3.711 ± 0.68
2.32AsnThr: 2.32 ± 0.504
3.34AsnVal: 3.34 ± 0.624
1.113AsnTrp: 1.113 ± 0.417
2.32AsnTyr: 2.32 ± 0.611
0.0AsnXaa: 0.0 ± 0.0
Pro
3.526ProAla: 3.526 ± 0.654
0.371ProCys: 0.371 ± 0.174
3.247ProAsp: 3.247 ± 0.396
3.34ProGlu: 3.34 ± 0.657
3.99ProPhe: 3.99 ± 0.683
3.155ProGly: 3.155 ± 0.75
0.742ProHis: 0.742 ± 0.281
3.526ProIle: 3.526 ± 0.554
2.134ProLys: 2.134 ± 0.371
6.587ProLeu: 6.587 ± 1.115
1.67ProMet: 1.67 ± 0.349
2.691ProAsn: 2.691 ± 0.779
5.752ProPro: 5.752 ± 0.931
2.783ProGln: 2.783 ± 0.713
3.247ProArg: 3.247 ± 0.634
5.196ProSer: 5.196 ± 0.959
2.876ProThr: 2.876 ± 0.457
3.526ProVal: 3.526 ± 0.811
0.649ProTrp: 0.649 ± 0.214
2.227ProTyr: 2.227 ± 0.639
0.0ProXaa: 0.0 ± 0.0
Gln
2.412GlnAla: 2.412 ± 0.543
0.835GlnCys: 0.835 ± 0.354
1.392GlnAsp: 1.392 ± 0.305
2.041GlnGlu: 2.041 ± 0.537
1.021GlnPhe: 1.021 ± 0.333
1.856GlnGly: 1.856 ± 0.256
0.649GlnHis: 0.649 ± 0.221
2.041GlnIle: 2.041 ± 0.385
2.691GlnLys: 2.691 ± 0.502
4.917GlnLeu: 4.917 ± 0.664
1.113GlnMet: 1.113 ± 0.269
2.505GlnAsn: 2.505 ± 0.506
2.876GlnPro: 2.876 ± 0.588
2.227GlnGln: 2.227 ± 0.594
2.505GlnArg: 2.505 ± 0.676
2.32GlnSer: 2.32 ± 0.456
3.433GlnThr: 3.433 ± 0.662
2.598GlnVal: 2.598 ± 0.434
0.557GlnTrp: 0.557 ± 0.221
1.67GlnTyr: 1.67 ± 0.422
0.0GlnXaa: 0.0 ± 0.0
Arg
3.804ArgAla: 3.804 ± 0.726
1.485ArgCys: 1.485 ± 0.441
2.32ArgAsp: 2.32 ± 0.496
4.454ArgGlu: 4.454 ± 1.123
3.247ArgPhe: 3.247 ± 0.847
4.082ArgGly: 4.082 ± 0.739
1.485ArgHis: 1.485 ± 0.342
2.227ArgIle: 2.227 ± 0.462
2.969ArgLys: 2.969 ± 0.509
4.917ArgLeu: 4.917 ± 0.803
1.113ArgMet: 1.113 ± 0.313
3.34ArgAsn: 3.34 ± 0.597
3.247ArgPro: 3.247 ± 0.773
1.948ArgGln: 1.948 ± 0.358
5.289ArgArg: 5.289 ± 1.489
4.082ArgSer: 4.082 ± 0.597
2.876ArgThr: 2.876 ± 0.719
3.34ArgVal: 3.34 ± 0.659
1.113ArgTrp: 1.113 ± 0.274
1.392ArgTyr: 1.392 ± 0.239
0.0ArgXaa: 0.0 ± 0.0
Ser
5.196SerAla: 5.196 ± 0.633
1.948SerCys: 1.948 ± 0.468
3.247SerAsp: 3.247 ± 0.532
4.639SerGlu: 4.639 ± 0.616
5.289SerPhe: 5.289 ± 0.68
5.103SerGly: 5.103 ± 0.736
1.485SerHis: 1.485 ± 0.305
3.618SerIle: 3.618 ± 0.537
3.99SerLys: 3.99 ± 0.742
8.258SerLeu: 8.258 ± 1.09
1.392SerMet: 1.392 ± 0.454
2.412SerAsn: 2.412 ± 0.471
3.618SerPro: 3.618 ± 0.619
2.598SerGln: 2.598 ± 0.468
3.711SerArg: 3.711 ± 0.639
7.051SerSer: 7.051 ± 1.064
3.34SerThr: 3.34 ± 0.519
4.917SerVal: 4.917 ± 0.786
1.577SerTrp: 1.577 ± 0.388
3.34SerTyr: 3.34 ± 0.605
0.0SerXaa: 0.0 ± 0.0
Thr
3.804ThrAla: 3.804 ± 0.808
1.021ThrCys: 1.021 ± 0.38
3.247ThrAsp: 3.247 ± 0.602
4.361ThrGlu: 4.361 ± 0.534
3.804ThrPhe: 3.804 ± 0.425
5.01ThrGly: 5.01 ± 0.74
1.206ThrHis: 1.206 ± 0.29
2.505ThrIle: 2.505 ± 0.458
2.32ThrLys: 2.32 ± 0.389
6.031ThrLeu: 6.031 ± 0.908
1.206ThrMet: 1.206 ± 0.389
2.598ThrAsn: 2.598 ± 0.542
3.247ThrPro: 3.247 ± 0.638
2.32ThrGln: 2.32 ± 0.382
3.34ThrArg: 3.34 ± 0.755
3.433ThrSer: 3.433 ± 0.575
2.969ThrThr: 2.969 ± 0.426
4.917ThrVal: 4.917 ± 0.537
1.113ThrTrp: 1.113 ± 0.303
2.041ThrTyr: 2.041 ± 0.509
0.0ThrXaa: 0.0 ± 0.0
Val
3.804ValAla: 3.804 ± 0.601
0.649ValCys: 0.649 ± 0.224
2.969ValAsp: 2.969 ± 0.705
2.969ValGlu: 2.969 ± 0.521
2.783ValPhe: 2.783 ± 0.559
2.876ValGly: 2.876 ± 0.466
1.113ValHis: 1.113 ± 0.309
2.691ValIle: 2.691 ± 0.443
2.412ValLys: 2.412 ± 0.634
5.938ValLeu: 5.938 ± 0.84
1.392ValMet: 1.392 ± 0.306
4.082ValAsn: 4.082 ± 0.72
3.526ValPro: 3.526 ± 0.694
2.691ValGln: 2.691 ± 0.59
4.082ValArg: 4.082 ± 0.81
5.01ValSer: 5.01 ± 0.619
4.732ValThr: 4.732 ± 0.814
3.711ValVal: 3.711 ± 0.496
0.835ValTrp: 0.835 ± 0.209
2.598ValTyr: 2.598 ± 0.731
0.0ValXaa: 0.0 ± 0.0
Trp
0.557TrpAla: 0.557 ± 0.175
0.371TrpCys: 0.371 ± 0.243
1.021TrpAsp: 1.021 ± 0.251
0.742TrpGlu: 0.742 ± 0.239
0.186TrpPhe: 0.186 ± 0.117
1.206TrpGly: 1.206 ± 0.31
0.464TrpHis: 0.464 ± 0.21
0.649TrpIle: 0.649 ± 0.263
1.485TrpLys: 1.485 ± 0.426
1.021TrpLeu: 1.021 ± 0.284
0.464TrpMet: 0.464 ± 0.198
0.464TrpAsn: 0.464 ± 0.23
0.742TrpPro: 0.742 ± 0.289
0.835TrpGln: 0.835 ± 0.246
0.835TrpArg: 0.835 ± 0.25
1.67TrpSer: 1.67 ± 0.343
1.577TrpThr: 1.577 ± 0.382
0.557TrpVal: 0.557 ± 0.206
0.464TrpTrp: 0.464 ± 0.177
0.464TrpTyr: 0.464 ± 0.176
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.67TyrAla: 1.67 ± 0.376
0.835TyrCys: 0.835 ± 0.214
1.392TyrAsp: 1.392 ± 0.437
1.485TyrGlu: 1.485 ± 0.373
2.227TyrPhe: 2.227 ± 0.438
2.783TyrGly: 2.783 ± 0.653
1.392TyrHis: 1.392 ± 0.358
1.763TyrIle: 1.763 ± 0.439
2.041TyrLys: 2.041 ± 0.434
3.804TyrLeu: 3.804 ± 0.711
0.649TyrMet: 0.649 ± 0.231
1.67TyrAsn: 1.67 ± 0.395
1.948TyrPro: 1.948 ± 0.414
1.67TyrGln: 1.67 ± 0.351
1.485TyrArg: 1.485 ± 0.381
2.876TyrSer: 2.876 ± 0.598
2.041TyrThr: 2.041 ± 0.487
2.412TyrVal: 2.412 ± 0.457
0.649TyrTrp: 0.649 ± 0.194
1.485TyrTyr: 1.485 ± 0.289
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 34 proteins (10779 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski