Amino acid dipepetide frequency for Wuhan heteroptera virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.607AlaAla: 2.607 ± 0.785
0.869AlaCys: 0.869 ± 0.312
2.281AlaAsp: 2.281 ± 0.506
1.629AlaGlu: 1.629 ± 0.229
2.39AlaPhe: 2.39 ± 0.745
1.521AlaGly: 1.521 ± 0.261
0.76AlaHis: 0.76 ± 0.256
4.345AlaIle: 4.345 ± 0.61
2.607AlaLys: 2.607 ± 0.494
4.671AlaLeu: 4.671 ± 0.795
1.303AlaMet: 1.303 ± 0.425
3.367AlaAsn: 3.367 ± 0.743
1.629AlaPro: 1.629 ± 0.364
1.521AlaGln: 1.521 ± 0.416
1.847AlaArg: 1.847 ± 0.285
4.128AlaSer: 4.128 ± 0.596
2.933AlaThr: 2.933 ± 0.774
1.955AlaVal: 1.955 ± 0.463
0.217AlaTrp: 0.217 ± 0.159
1.955AlaTyr: 1.955 ± 0.315
0.0AlaXaa: 0.0 ± 0.0
Cys
0.543CysAla: 0.543 ± 0.404
0.0CysCys: 0.0 ± 0.0
0.76CysAsp: 0.76 ± 0.23
0.652CysGlu: 0.652 ± 0.271
0.434CysPhe: 0.434 ± 0.16
0.652CysGly: 0.652 ± 0.301
0.434CysHis: 0.434 ± 0.323
0.76CysIle: 0.76 ± 0.256
0.76CysLys: 0.76 ± 0.272
1.195CysLeu: 1.195 ± 0.329
0.217CysMet: 0.217 ± 0.185
0.652CysAsn: 0.652 ± 0.147
0.217CysPro: 0.217 ± 0.159
0.652CysGln: 0.652 ± 0.194
0.217CysArg: 0.217 ± 0.123
1.086CysSer: 1.086 ± 0.379
1.303CysThr: 1.303 ± 0.419
0.76CysVal: 0.76 ± 0.318
0.0CysTrp: 0.0 ± 0.0
1.086CysTyr: 1.086 ± 0.358
0.0CysXaa: 0.0 ± 0.0
Asp
2.281AspAla: 2.281 ± 0.658
0.76AspCys: 0.76 ± 0.345
5.974AspAsp: 5.974 ± 0.725
4.454AspGlu: 4.454 ± 0.479
2.064AspPhe: 2.064 ± 0.358
1.847AspGly: 1.847 ± 0.412
0.869AspHis: 0.869 ± 0.289
5.54AspIle: 5.54 ± 0.675
4.236AspLys: 4.236 ± 0.849
6.3AspLeu: 6.3 ± 0.771
0.543AspMet: 0.543 ± 0.195
5.431AspAsn: 5.431 ± 0.889
1.629AspPro: 1.629 ± 0.384
3.041AspGln: 3.041 ± 0.592
2.933AspArg: 2.933 ± 0.885
3.041AspSer: 3.041 ± 0.432
2.39AspThr: 2.39 ± 0.424
5.323AspVal: 5.323 ± 0.342
0.434AspTrp: 0.434 ± 0.204
4.019AspTyr: 4.019 ± 0.755
0.0AspXaa: 0.0 ± 0.0
Glu
2.064GluAla: 2.064 ± 0.422
0.543GluCys: 0.543 ± 0.184
2.172GluAsp: 2.172 ± 0.248
1.738GluGlu: 1.738 ± 0.393
2.824GluPhe: 2.824 ± 0.554
1.195GluGly: 1.195 ± 0.283
1.195GluHis: 1.195 ± 0.206
3.802GluIle: 3.802 ± 0.514
3.259GluLys: 3.259 ± 0.478
5.648GluLeu: 5.648 ± 0.554
0.869GluMet: 0.869 ± 0.314
3.476GluAsn: 3.476 ± 0.617
2.172GluPro: 2.172 ± 0.399
1.847GluGln: 1.847 ± 0.343
1.629GluArg: 1.629 ± 0.528
3.476GluSer: 3.476 ± 0.615
2.933GluThr: 2.933 ± 0.591
3.802GluVal: 3.802 ± 0.503
0.326GluTrp: 0.326 ± 0.187
2.498GluTyr: 2.498 ± 0.4
0.0GluXaa: 0.0 ± 0.0
Phe
1.847PheAla: 1.847 ± 0.223
0.652PheCys: 0.652 ± 0.342
3.15PheAsp: 3.15 ± 0.563
2.824PheGlu: 2.824 ± 0.419
2.498PhePhe: 2.498 ± 0.65
3.041PheGly: 3.041 ± 0.532
1.086PheHis: 1.086 ± 0.324
3.91PheIle: 3.91 ± 0.686
4.888PheLys: 4.888 ± 0.541
4.019PheLeu: 4.019 ± 0.639
0.978PheMet: 0.978 ± 0.251
5.648PheAsn: 5.648 ± 0.882
2.716PhePro: 2.716 ± 0.535
1.955PheGln: 1.955 ± 0.435
1.412PheArg: 1.412 ± 0.359
4.019PheSer: 4.019 ± 0.814
4.671PheThr: 4.671 ± 0.829
2.39PheVal: 2.39 ± 0.595
0.326PheTrp: 0.326 ± 0.23
2.172PheTyr: 2.172 ± 0.333
0.0PheXaa: 0.0 ± 0.0
Gly
1.195GlyAla: 1.195 ± 0.31
1.086GlyCys: 1.086 ± 0.348
1.629GlyAsp: 1.629 ± 0.497
2.172GlyGlu: 2.172 ± 0.387
3.15GlyPhe: 3.15 ± 0.518
1.195GlyGly: 1.195 ± 0.294
0.76GlyHis: 0.76 ± 0.174
3.802GlyIle: 3.802 ± 0.401
1.847GlyLys: 1.847 ± 0.358
3.15GlyLeu: 3.15 ± 0.712
1.086GlyMet: 1.086 ± 0.272
2.498GlyAsn: 2.498 ± 0.536
1.303GlyPro: 1.303 ± 0.332
1.521GlyGln: 1.521 ± 0.521
1.412GlyArg: 1.412 ± 0.482
2.716GlySer: 2.716 ± 0.596
2.172GlyThr: 2.172 ± 0.379
2.064GlyVal: 2.064 ± 0.152
0.326GlyTrp: 0.326 ± 0.205
2.39GlyTyr: 2.39 ± 0.442
0.0GlyXaa: 0.0 ± 0.0
His
0.434HisAla: 0.434 ± 0.144
0.543HisCys: 0.543 ± 0.264
1.195HisAsp: 1.195 ± 0.312
0.652HisGlu: 0.652 ± 0.216
1.195HisPhe: 1.195 ± 0.398
0.543HisGly: 0.543 ± 0.228
0.326HisHis: 0.326 ± 0.21
2.281HisIle: 2.281 ± 0.476
0.76HisLys: 0.76 ± 0.23
1.955HisLeu: 1.955 ± 0.553
0.109HisMet: 0.109 ± 0.093
1.521HisAsn: 1.521 ± 0.491
0.76HisPro: 0.76 ± 0.267
0.217HisGln: 0.217 ± 0.271
0.543HisArg: 0.543 ± 0.235
1.521HisSer: 1.521 ± 0.298
0.76HisThr: 0.76 ± 0.19
1.847HisVal: 1.847 ± 0.374
0.109HisTrp: 0.109 ± 0.107
0.543HisTyr: 0.543 ± 0.245
0.0HisXaa: 0.0 ± 0.0
Ile
5.323IleAla: 5.323 ± 0.771
0.652IleCys: 0.652 ± 0.208
6.517IleAsp: 6.517 ± 0.831
4.454IleGlu: 4.454 ± 0.709
4.562IlePhe: 4.562 ± 0.535
4.128IleGly: 4.128 ± 1.074
0.978IleHis: 0.978 ± 0.234
6.3IleIle: 6.3 ± 1.124
5.214IleLys: 5.214 ± 0.436
9.342IleLeu: 9.342 ± 1.18
0.76IleMet: 0.76 ± 0.2
7.712IleAsn: 7.712 ± 0.861
3.367IlePro: 3.367 ± 0.307
3.693IleGln: 3.693 ± 0.513
2.498IleArg: 2.498 ± 0.591
7.278IleSer: 7.278 ± 0.966
7.386IleThr: 7.386 ± 0.966
4.779IleVal: 4.779 ± 0.703
0.434IleTrp: 0.434 ± 0.202
3.802IleTyr: 3.802 ± 0.575
0.0IleXaa: 0.0 ± 0.0
Lys
2.933LysAla: 2.933 ± 0.519
0.978LysCys: 0.978 ± 0.327
4.562LysAsp: 4.562 ± 0.786
3.693LysGlu: 3.693 ± 0.704
3.91LysPhe: 3.91 ± 0.585
1.955LysGly: 1.955 ± 0.617
0.978LysHis: 0.978 ± 0.299
5.757LysIle: 5.757 ± 0.745
5.105LysLys: 5.105 ± 0.51
9.45LysLeu: 9.45 ± 0.581
1.955LysMet: 1.955 ± 0.395
4.888LysAsn: 4.888 ± 0.544
2.064LysPro: 2.064 ± 0.568
2.716LysGln: 2.716 ± 0.463
2.281LysArg: 2.281 ± 0.438
5.214LysSer: 5.214 ± 0.551
4.888LysThr: 4.888 ± 0.513
2.824LysVal: 2.824 ± 0.759
0.326LysTrp: 0.326 ± 0.184
2.281LysTyr: 2.281 ± 0.527
0.0LysXaa: 0.0 ± 0.0
Leu
5.648LeuAla: 5.648 ± 0.886
1.412LeuCys: 1.412 ± 0.463
7.278LeuAsp: 7.278 ± 0.819
5.105LeuGlu: 5.105 ± 0.896
6.735LeuPhe: 6.735 ± 0.748
4.019LeuGly: 4.019 ± 0.455
1.955LeuHis: 1.955 ± 0.395
10.645LeuIle: 10.645 ± 1.318
8.038LeuLys: 8.038 ± 0.895
9.124LeuLeu: 9.124 ± 0.859
2.172LeuMet: 2.172 ± 0.476
8.038LeuAsn: 8.038 ± 0.803
4.345LeuPro: 4.345 ± 0.618
3.476LeuGln: 3.476 ± 0.54
3.259LeuArg: 3.259 ± 0.507
8.473LeuSer: 8.473 ± 0.532
7.169LeuThr: 7.169 ± 0.689
4.562LeuVal: 4.562 ± 0.512
0.543LeuTrp: 0.543 ± 0.356
4.671LeuTyr: 4.671 ± 0.764
0.0LeuXaa: 0.0 ± 0.0
Met
0.76MetAla: 0.76 ± 0.26
0.434MetCys: 0.434 ± 0.216
0.76MetAsp: 0.76 ± 0.214
1.412MetGlu: 1.412 ± 0.453
1.412MetPhe: 1.412 ± 0.321
0.652MetGly: 0.652 ± 0.183
0.109MetHis: 0.109 ± 0.094
1.086MetIle: 1.086 ± 0.443
1.195MetLys: 1.195 ± 0.367
2.716MetLeu: 2.716 ± 0.416
0.652MetMet: 0.652 ± 0.274
1.955MetAsn: 1.955 ± 0.36
0.434MetPro: 0.434 ± 0.198
0.326MetGln: 0.326 ± 0.133
0.76MetArg: 0.76 ± 0.255
1.412MetSer: 1.412 ± 0.27
1.195MetThr: 1.195 ± 0.318
1.086MetVal: 1.086 ± 0.245
0.109MetTrp: 0.109 ± 0.095
0.434MetTyr: 0.434 ± 0.203
0.0MetXaa: 0.0 ± 0.0
Asn
3.91AsnAla: 3.91 ± 0.619
0.76AsnCys: 0.76 ± 0.269
5.214AsnAsp: 5.214 ± 0.74
3.802AsnGlu: 3.802 ± 0.612
4.128AsnPhe: 4.128 ± 0.676
3.259AsnGly: 3.259 ± 0.594
1.521AsnHis: 1.521 ± 0.234
10.319AsnIle: 10.319 ± 1.159
5.431AsnLys: 5.431 ± 0.537
8.799AsnLeu: 8.799 ± 0.617
0.978AsnMet: 0.978 ± 0.33
7.386AsnAsn: 7.386 ± 0.991
2.607AsnPro: 2.607 ± 0.588
3.91AsnGln: 3.91 ± 0.639
2.498AsnArg: 2.498 ± 0.451
5.866AsnSer: 5.866 ± 0.928
3.476AsnThr: 3.476 ± 0.751
4.128AsnVal: 4.128 ± 0.657
0.326AsnTrp: 0.326 ± 0.186
3.91AsnTyr: 3.91 ± 0.77
0.0AsnXaa: 0.0 ± 0.0
Pro
1.195ProAla: 1.195 ± 0.386
0.217ProCys: 0.217 ± 0.148
1.412ProAsp: 1.412 ± 0.407
1.412ProGlu: 1.412 ± 0.411
1.195ProPhe: 1.195 ± 0.307
1.195ProGly: 1.195 ± 0.322
0.434ProHis: 0.434 ± 0.198
3.367ProIle: 3.367 ± 0.768
2.281ProLys: 2.281 ± 0.443
4.019ProLeu: 4.019 ± 0.711
0.869ProMet: 0.869 ± 0.285
3.041ProAsn: 3.041 ± 0.412
1.303ProPro: 1.303 ± 0.39
1.086ProGln: 1.086 ± 0.256
1.086ProArg: 1.086 ± 0.34
3.585ProSer: 3.585 ± 0.521
3.476ProThr: 3.476 ± 0.672
2.064ProVal: 2.064 ± 0.566
0.326ProTrp: 0.326 ± 0.207
0.869ProTyr: 0.869 ± 0.301
0.0ProXaa: 0.0 ± 0.0
Gln
1.955GlnAla: 1.955 ± 0.349
0.434GlnCys: 0.434 ± 0.213
1.955GlnAsp: 1.955 ± 0.503
0.978GlnGlu: 0.978 ± 0.33
2.064GlnPhe: 2.064 ± 0.615
0.652GlnGly: 0.652 ± 0.279
0.869GlnHis: 0.869 ± 0.255
3.585GlnIle: 3.585 ± 0.598
2.933GlnLys: 2.933 ± 0.535
5.105GlnLeu: 5.105 ± 0.244
0.869GlnMet: 0.869 ± 0.378
3.259GlnAsn: 3.259 ± 0.554
1.086GlnPro: 1.086 ± 0.284
1.521GlnGln: 1.521 ± 0.387
1.195GlnArg: 1.195 ± 0.459
2.933GlnSer: 2.933 ± 0.487
3.259GlnThr: 3.259 ± 0.413
1.738GlnVal: 1.738 ± 0.342
0.326GlnTrp: 0.326 ± 0.174
1.521GlnTyr: 1.521 ± 0.307
0.0GlnXaa: 0.0 ± 0.0
Arg
1.521ArgAla: 1.521 ± 0.507
0.326ArgCys: 0.326 ± 0.171
2.281ArgAsp: 2.281 ± 0.584
1.629ArgGlu: 1.629 ± 0.302
1.955ArgPhe: 1.955 ± 0.622
1.412ArgGly: 1.412 ± 0.264
0.434ArgHis: 0.434 ± 0.194
2.824ArgIle: 2.824 ± 0.598
2.064ArgLys: 2.064 ± 0.341
3.476ArgLeu: 3.476 ± 0.768
0.652ArgMet: 0.652 ± 0.204
2.716ArgAsn: 2.716 ± 0.525
0.434ArgPro: 0.434 ± 0.21
1.195ArgGln: 1.195 ± 0.187
1.738ArgArg: 1.738 ± 0.493
2.933ArgSer: 2.933 ± 0.53
2.064ArgThr: 2.064 ± 0.437
1.738ArgVal: 1.738 ± 0.438
0.109ArgTrp: 0.109 ± 0.093
2.281ArgTyr: 2.281 ± 0.483
0.0ArgXaa: 0.0 ± 0.0
Ser
3.15SerAla: 3.15 ± 0.321
0.76SerCys: 0.76 ± 0.212
5.323SerAsp: 5.323 ± 0.661
3.367SerGlu: 3.367 ± 0.635
3.585SerPhe: 3.585 ± 0.474
3.476SerGly: 3.476 ± 0.593
1.847SerHis: 1.847 ± 0.358
5.974SerIle: 5.974 ± 0.704
4.888SerLys: 4.888 ± 0.498
7.495SerLeu: 7.495 ± 1.016
1.303SerMet: 1.303 ± 0.432
5.757SerAsn: 5.757 ± 1.274
2.716SerPro: 2.716 ± 0.517
3.693SerGln: 3.693 ± 0.591
2.39SerArg: 2.39 ± 0.536
7.169SerSer: 7.169 ± 1.041
5.54SerThr: 5.54 ± 0.608
4.128SerVal: 4.128 ± 0.948
0.543SerTrp: 0.543 ± 0.203
3.367SerTyr: 3.367 ± 0.794
0.0SerXaa: 0.0 ± 0.0
Thr
2.607ThrAla: 2.607 ± 0.58
0.76ThrCys: 0.76 ± 0.335
3.476ThrAsp: 3.476 ± 0.79
2.933ThrGlu: 2.933 ± 0.344
4.128ThrPhe: 4.128 ± 0.814
2.933ThrGly: 2.933 ± 0.319
0.869ThrHis: 0.869 ± 0.295
5.431ThrIle: 5.431 ± 0.781
4.236ThrLys: 4.236 ± 0.705
8.69ThrLeu: 8.69 ± 1.12
1.195ThrMet: 1.195 ± 0.303
5.431ThrAsn: 5.431 ± 0.787
1.847ThrPro: 1.847 ± 0.248
2.933ThrGln: 2.933 ± 0.436
2.281ThrArg: 2.281 ± 0.365
4.779ThrSer: 4.779 ± 0.735
4.888ThrThr: 4.888 ± 1.202
3.041ThrVal: 3.041 ± 0.602
0.543ThrTrp: 0.543 ± 0.174
3.585ThrTyr: 3.585 ± 0.726
0.0ThrXaa: 0.0 ± 0.0
Val
2.281ValAla: 2.281 ± 0.398
0.434ValCys: 0.434 ± 0.232
3.259ValAsp: 3.259 ± 0.556
2.824ValGlu: 2.824 ± 0.481
3.367ValPhe: 3.367 ± 0.478
1.629ValGly: 1.629 ± 0.336
0.869ValHis: 0.869 ± 0.272
3.91ValIle: 3.91 ± 1.085
4.779ValLys: 4.779 ± 0.993
5.866ValLeu: 5.866 ± 0.565
1.195ValMet: 1.195 ± 0.387
5.323ValAsn: 5.323 ± 0.567
2.281ValPro: 2.281 ± 0.463
1.629ValGln: 1.629 ± 0.371
1.738ValArg: 1.738 ± 0.533
3.585ValSer: 3.585 ± 0.4
2.933ValThr: 2.933 ± 0.942
2.716ValVal: 2.716 ± 0.413
0.543ValTrp: 0.543 ± 0.249
2.824ValTyr: 2.824 ± 0.545
0.0ValXaa: 0.0 ± 0.0
Trp
0.217TrpAla: 0.217 ± 0.147
0.109TrpCys: 0.109 ± 0.093
0.217TrpAsp: 0.217 ± 0.213
0.109TrpGlu: 0.109 ± 0.093
0.434TrpPhe: 0.434 ± 0.222
0.217TrpGly: 0.217 ± 0.147
0.109TrpHis: 0.109 ± 0.094
0.978TrpIle: 0.978 ± 0.359
0.434TrpLys: 0.434 ± 0.169
0.543TrpLeu: 0.543 ± 0.167
0.0TrpMet: 0.0 ± 0.0
0.543TrpAsn: 0.543 ± 0.228
0.217TrpPro: 0.217 ± 0.186
0.326TrpGln: 0.326 ± 0.207
0.326TrpArg: 0.326 ± 0.188
0.434TrpSer: 0.434 ± 0.188
0.434TrpThr: 0.434 ± 0.241
0.326TrpVal: 0.326 ± 0.163
0.0TrpTrp: 0.0 ± 0.0
0.434TrpTyr: 0.434 ± 0.184
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.064TyrAla: 2.064 ± 0.483
0.652TyrCys: 0.652 ± 0.251
3.693TyrAsp: 3.693 ± 0.443
1.629TyrGlu: 1.629 ± 0.442
2.172TyrPhe: 2.172 ± 0.306
1.955TyrGly: 1.955 ± 0.594
1.412TyrHis: 1.412 ± 0.342
4.562TyrIle: 4.562 ± 0.765
3.802TyrLys: 3.802 ± 0.383
5.105TyrLeu: 5.105 ± 0.719
1.086TyrMet: 1.086 ± 0.263
3.585TyrAsn: 3.585 ± 0.575
1.303TyrPro: 1.303 ± 0.335
0.978TyrGln: 0.978 ± 0.208
1.738TyrArg: 1.738 ± 0.538
2.824TyrSer: 2.824 ± 0.633
2.716TyrThr: 2.716 ± 0.515
2.716TyrVal: 2.716 ± 0.625
0.543TyrTrp: 0.543 ± 0.22
2.824TyrTyr: 2.824 ± 0.797
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (9207 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski