Circoviridae TaCV2

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; unclassified Circoviridae

Average proteome isoelectric point is 6.88

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2L2P5L7|A0A2L2P5L7_9CIRC ORF3 OS=Circoviridae TaCV2 OX=2094725 PE=4 SV=1
MM1 pKa = 7.39SNVYY5 pKa = 8.73TLTLLKK11 pKa = 10.24EE12 pKa = 4.3KK13 pKa = 10.23EE14 pKa = 4.31SEE16 pKa = 4.25VSNVCINRR24 pKa = 11.84VNDD27 pKa = 4.05YY28 pKa = 11.07INSLSDD34 pKa = 3.45AEE36 pKa = 4.18NTIDD40 pKa = 4.45IVEE43 pKa = 5.03CIMKK47 pKa = 10.26DD48 pKa = 3.54VNHH51 pKa = 7.55PIHH54 pKa = 7.33ADD56 pKa = 3.27LLSIVNDD63 pKa = 3.16RR64 pKa = 11.84DD65 pKa = 3.46MFNSFVCKK73 pKa = 10.25LDD75 pKa = 3.53LSDD78 pKa = 4.97RR79 pKa = 11.84DD80 pKa = 3.97RR81 pKa = 11.84ACMLSFSNGIAAMSCDD97 pKa = 3.86VALKK101 pKa = 10.48DD102 pKa = 3.59YY103 pKa = 9.68TINNLVEE110 pKa = 4.23SQSRR114 pKa = 11.84LEE116 pKa = 4.43SEE118 pKa = 4.3NEE120 pKa = 3.76LLKK123 pKa = 10.82QEE125 pKa = 4.06LSSRR129 pKa = 11.84NRR131 pKa = 11.84LSDD134 pKa = 3.46EE135 pKa = 3.92ALEE138 pKa = 4.98SILSSSARR146 pKa = 11.84FHH148 pKa = 6.35KK149 pKa = 10.45RR150 pKa = 11.84KK151 pKa = 9.51ILSKK155 pKa = 9.04VDD157 pKa = 3.07VYY159 pKa = 11.57KK160 pKa = 10.96RR161 pKa = 11.84FGLSYY166 pKa = 11.16

Molecular weight: 18.9 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2L2P5L6|A0A2L2P5L6_9CIRC ATP-dependent helicase Rep OS=Circoviridae TaCV2 OX=2094725 PE=3 SV=1
MM1 pKa = 7.87ASPIDD6 pKa = 3.37KK7 pKa = 10.03VRR9 pKa = 11.84RR10 pKa = 11.84YY11 pKa = 10.11KK12 pKa = 10.81KK13 pKa = 9.46LTSTFLPEE21 pKa = 3.48NTTEE25 pKa = 3.78IKK27 pKa = 10.49EE28 pKa = 4.12ILKK31 pKa = 10.35KK32 pKa = 10.3EE33 pKa = 3.89YY34 pKa = 11.23AMDD37 pKa = 3.96YY38 pKa = 10.54LKK40 pKa = 10.79KK41 pKa = 10.52ALNIQEE47 pKa = 4.35RR48 pKa = 11.84TTKK51 pKa = 9.36TRR53 pKa = 11.84YY54 pKa = 9.85CRR56 pKa = 11.84DD57 pKa = 3.19HH58 pKa = 7.0KK59 pKa = 11.03ISVHH63 pKa = 5.26TLNQGLKK70 pKa = 10.21ALNVNCNKK78 pKa = 9.34QHH80 pKa = 5.86NRR82 pKa = 11.84NKK84 pKa = 10.39NKK86 pKa = 10.03EE87 pKa = 4.22PEE89 pKa = 4.12HH90 pKa = 5.41QTTKK94 pKa = 10.49SKK96 pKa = 9.78RR97 pKa = 11.84TQKK100 pKa = 10.65SKK102 pKa = 9.28NTHH105 pKa = 3.88VHH107 pKa = 5.73NDD109 pKa = 3.17YY110 pKa = 11.29AAGSKK115 pKa = 9.42TEE117 pKa = 3.81MHH119 pKa = 6.34EE120 pKa = 4.06TSQYY124 pKa = 10.62SIKK127 pKa = 10.88EE128 pKa = 3.73NDD130 pKa = 3.32EE131 pKa = 4.17TQTEE135 pKa = 4.1IDD137 pKa = 4.06NTDD140 pKa = 3.14LDD142 pKa = 3.81IDD144 pKa = 3.75IKK146 pKa = 11.04EE147 pKa = 4.06LAKK150 pKa = 10.73KK151 pKa = 8.3ITKK154 pKa = 9.45KK155 pKa = 10.21SKK157 pKa = 10.8RR158 pKa = 11.84EE159 pKa = 3.63IQQPIDD165 pKa = 2.99WSNRR169 pKa = 11.84EE170 pKa = 3.96PGKK173 pKa = 10.75LL174 pKa = 3.36

Molecular weight: 20.44 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

661

166

321

220.3

26.0

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

3.177 ± 0.839

1.664 ± 0.485

6.203 ± 0.818

9.985 ± 1.392

2.572 ± 0.764

3.177 ± 1.141

1.815 ± 0.899

7.564 ± 0.535

11.498 ± 2.127

7.716 ± 1.562

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.421 ± 0.288

6.657 ± 1.054

2.118 ± 0.551

4.841 ± 1.374

5.749 ± 0.217

7.11 ± 2.473

6.203 ± 1.759

3.933 ± 1.197

1.21 ± 0.622

4.387 ± 0.772
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski