Amino acid dipepetide frequency for Pepper vein yellows virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.538AlaAla: 4.538 ± 1.001
1.297AlaCys: 1.297 ± 0.538
3.241AlaAsp: 3.241 ± 0.642
4.538AlaGlu: 4.538 ± 0.533
1.621AlaPhe: 1.621 ± 0.272
4.538AlaGly: 4.538 ± 0.535
2.269AlaHis: 2.269 ± 0.842
0.972AlaIle: 0.972 ± 0.648
2.917AlaLys: 2.917 ± 0.278
6.807AlaLeu: 6.807 ± 1.015
1.621AlaMet: 1.621 ± 0.674
1.621AlaAsn: 1.621 ± 0.395
5.835AlaPro: 5.835 ± 1.381
3.241AlaGln: 3.241 ± 1.234
1.945AlaArg: 1.945 ± 0.767
6.807AlaSer: 6.807 ± 1.234
3.89AlaThr: 3.89 ± 0.726
1.621AlaVal: 1.621 ± 0.468
1.621AlaTrp: 1.621 ± 0.319
2.917AlaTyr: 2.917 ± 0.626
0.0AlaXaa: 0.0 ± 0.0
Cys
1.297CysAla: 1.297 ± 0.687
0.324CysCys: 0.324 ± 0.36
0.648CysAsp: 0.648 ± 0.263
0.648CysGlu: 0.648 ± 0.449
0.0CysPhe: 0.0 ± 0.0
0.972CysGly: 0.972 ± 0.47
0.972CysHis: 0.972 ± 0.374
0.324CysIle: 0.324 ± 0.21
1.945CysLys: 1.945 ± 0.616
2.269CysLeu: 2.269 ± 0.697
0.324CysMet: 0.324 ± 0.271
0.972CysAsn: 0.972 ± 0.374
0.648CysPro: 0.648 ± 0.362
0.324CysGln: 0.324 ± 0.304
0.324CysArg: 0.324 ± 0.36
0.648CysSer: 0.648 ± 0.42
0.648CysThr: 0.648 ± 0.269
1.297CysVal: 1.297 ± 0.513
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.945AspAla: 1.945 ± 0.71
0.324AspCys: 0.324 ± 0.21
2.593AspAsp: 2.593 ± 0.584
3.89AspGlu: 3.89 ± 0.56
2.269AspPhe: 2.269 ± 0.875
2.593AspGly: 2.593 ± 0.5
1.945AspHis: 1.945 ± 0.481
0.324AspIle: 0.324 ± 0.36
1.945AspLys: 1.945 ± 1.625
4.538AspLeu: 4.538 ± 0.413
0.648AspMet: 0.648 ± 0.42
1.621AspAsn: 1.621 ± 0.445
2.593AspPro: 2.593 ± 0.945
1.297AspGln: 1.297 ± 0.505
1.621AspArg: 1.621 ± 0.573
3.89AspSer: 3.89 ± 1.232
1.621AspThr: 1.621 ± 0.758
0.972AspVal: 0.972 ± 0.648
1.297AspTrp: 1.297 ± 0.571
0.648AspTyr: 0.648 ± 0.449
0.0AspXaa: 0.0 ± 0.0
Glu
5.835GluAla: 5.835 ± 0.925
0.324GluCys: 0.324 ± 0.271
4.862GluAsp: 4.862 ± 0.311
6.159GluGlu: 6.159 ± 1.272
2.917GluPhe: 2.917 ± 0.501
4.538GluGly: 4.538 ± 1.413
0.324GluHis: 0.324 ± 0.21
2.269GluIle: 2.269 ± 0.77
8.104GluLys: 8.104 ± 2.386
3.89GluLeu: 3.89 ± 1.093
2.269GluMet: 2.269 ± 0.708
2.917GluAsn: 2.917 ± 0.77
3.241GluPro: 3.241 ± 0.471
0.972GluGln: 0.972 ± 0.393
3.566GluArg: 3.566 ± 0.477
4.538GluSer: 4.538 ± 0.434
2.593GluThr: 2.593 ± 0.476
3.89GluVal: 3.89 ± 1.187
2.269GluTrp: 2.269 ± 0.359
1.621GluTyr: 1.621 ± 1.079
0.0GluXaa: 0.0 ± 0.0
Phe
2.593PheAla: 2.593 ± 0.69
0.324PheCys: 0.324 ± 0.21
0.972PheAsp: 0.972 ± 0.491
2.269PheGlu: 2.269 ± 0.371
2.917PhePhe: 2.917 ± 0.481
3.89PheGly: 3.89 ± 0.854
0.324PheHis: 0.324 ± 0.271
2.593PheIle: 2.593 ± 0.692
1.945PheLys: 1.945 ± 0.373
3.241PheLeu: 3.241 ± 1.678
1.297PheMet: 1.297 ± 0.538
2.269PheAsn: 2.269 ± 0.422
0.972PhePro: 0.972 ± 0.425
5.511PheGln: 5.511 ± 0.724
3.241PheArg: 3.241 ± 0.638
2.269PheSer: 2.269 ± 0.64
4.538PheThr: 4.538 ± 1.392
3.566PheVal: 3.566 ± 0.551
0.324PheTrp: 0.324 ± 0.271
0.648PheTyr: 0.648 ± 0.269
0.0PheXaa: 0.0 ± 0.0
Gly
3.566GlyAla: 3.566 ± 0.588
0.972GlyCys: 0.972 ± 0.167
1.621GlyAsp: 1.621 ± 0.272
4.862GlyGlu: 4.862 ± 0.442
3.566GlyPhe: 3.566 ± 0.958
7.78GlyGly: 7.78 ± 2.55
1.297GlyHis: 1.297 ± 0.311
2.269GlyIle: 2.269 ± 0.371
4.862GlyLys: 4.862 ± 0.885
2.917GlyLeu: 2.917 ± 1.042
0.324GlyMet: 0.324 ± 0.319
5.186GlyAsn: 5.186 ± 1.459
3.566GlyPro: 3.566 ± 0.493
2.269GlyGln: 2.269 ± 0.422
6.159GlyArg: 6.159 ± 1.051
10.373GlySer: 10.373 ± 1.734
4.538GlyThr: 4.538 ± 0.808
4.214GlyVal: 4.214 ± 0.749
1.621GlyTrp: 1.621 ± 0.395
2.593GlyTyr: 2.593 ± 0.82
0.0GlyXaa: 0.0 ± 0.0
His
1.621HisAla: 1.621 ± 0.548
1.621HisCys: 1.621 ± 0.759
1.945HisAsp: 1.945 ± 0.561
2.269HisGlu: 2.269 ± 0.422
1.297HisPhe: 1.297 ± 0.311
1.621HisGly: 1.621 ± 0.371
0.972HisHis: 0.972 ± 0.378
0.648HisIle: 0.648 ± 0.263
1.297HisLys: 1.297 ± 0.218
1.621HisLeu: 1.621 ± 1.395
0.0HisMet: 0.0 ± 0.0
0.648HisAsn: 0.648 ± 0.38
1.297HisPro: 1.297 ± 0.49
0.0HisGln: 0.0 ± 0.0
0.648HisArg: 0.648 ± 0.72
0.972HisSer: 0.972 ± 0.374
0.648HisThr: 0.648 ± 0.269
1.297HisVal: 1.297 ± 0.364
0.648HisTrp: 0.648 ± 0.269
0.324HisTyr: 0.324 ± 0.21
0.0HisXaa: 0.0 ± 0.0
Ile
2.917IleAla: 2.917 ± 0.811
0.648IleCys: 0.648 ± 0.362
1.297IleAsp: 1.297 ± 0.738
2.269IleGlu: 2.269 ± 0.799
3.566IlePhe: 3.566 ± 0.876
0.972IleGly: 0.972 ± 0.393
0.0IleHis: 0.0 ± 0.0
0.324IleIle: 0.324 ± 0.271
1.297IleLys: 1.297 ± 0.505
0.648IleLeu: 0.648 ± 0.449
0.324IleMet: 0.324 ± 0.21
1.297IleAsn: 1.297 ± 0.462
4.538IlePro: 4.538 ± 0.654
1.621IleGln: 1.621 ± 0.818
2.269IleArg: 2.269 ± 0.699
4.862IleSer: 4.862 ± 0.908
2.269IleThr: 2.269 ± 1.041
2.917IleVal: 2.917 ± 0.602
0.648IleTrp: 0.648 ± 0.269
1.297IleTyr: 1.297 ± 1.112
0.0IleXaa: 0.0 ± 0.0
Lys
4.538LysAla: 4.538 ± 0.621
0.648LysCys: 0.648 ± 0.362
3.566LysAsp: 3.566 ± 1.001
1.621LysGlu: 1.621 ± 0.693
1.945LysPhe: 1.945 ± 0.616
5.186LysGly: 5.186 ± 0.759
0.324LysHis: 0.324 ± 0.271
3.566LysIle: 3.566 ± 0.551
1.621LysLys: 1.621 ± 0.843
5.511LysLeu: 5.511 ± 0.295
1.621LysMet: 1.621 ± 0.407
2.269LysAsn: 2.269 ± 0.681
4.214LysPro: 4.214 ± 0.663
1.297LysGln: 1.297 ± 0.545
2.917LysArg: 2.917 ± 0.883
6.483LysSer: 6.483 ± 2.006
3.89LysThr: 3.89 ± 1.139
3.566LysVal: 3.566 ± 0.824
0.972LysTrp: 0.972 ± 0.491
1.297LysTyr: 1.297 ± 0.361
0.324LysXaa: 0.324 ± 0.271
Leu
5.186LeuAla: 5.186 ± 1.567
1.297LeuCys: 1.297 ± 0.545
3.566LeuAsp: 3.566 ± 0.709
6.159LeuGlu: 6.159 ± 1.49
4.538LeuPhe: 4.538 ± 1.109
3.566LeuGly: 3.566 ± 0.935
1.945LeuHis: 1.945 ± 0.738
2.917LeuIle: 2.917 ± 0.976
3.89LeuLys: 3.89 ± 0.535
6.807LeuLeu: 6.807 ± 1.23
1.297LeuMet: 1.297 ± 0.538
1.297LeuAsn: 1.297 ± 0.443
5.835LeuPro: 5.835 ± 0.998
2.593LeuGln: 2.593 ± 0.804
5.186LeuArg: 5.186 ± 0.335
6.807LeuSer: 6.807 ± 1.187
4.862LeuThr: 4.862 ± 0.599
4.862LeuVal: 4.862 ± 1.47
3.241LeuTrp: 3.241 ± 0.615
1.945LeuTyr: 1.945 ± 0.402
0.0LeuXaa: 0.0 ± 0.0
Met
3.241MetAla: 3.241 ± 0.677
0.0MetCys: 0.0 ± 0.0
0.324MetAsp: 0.324 ± 0.36
0.972MetGlu: 0.972 ± 0.738
0.648MetPhe: 0.648 ± 0.269
0.324MetGly: 0.324 ± 0.21
0.0MetHis: 0.0 ± 0.0
0.648MetIle: 0.648 ± 0.263
0.972MetLys: 0.972 ± 0.534
1.621MetLeu: 1.621 ± 0.736
0.648MetMet: 0.648 ± 0.269
1.621MetAsn: 1.621 ± 0.698
0.648MetPro: 0.648 ± 0.269
1.297MetGln: 1.297 ± 0.361
0.648MetArg: 0.648 ± 0.269
2.593MetSer: 2.593 ± 0.985
1.297MetThr: 1.297 ± 0.538
1.945MetVal: 1.945 ± 0.402
0.0MetTrp: 0.0 ± 0.0
0.324MetTyr: 0.324 ± 0.271
0.0MetXaa: 0.0 ± 0.0
Asn
0.648AsnAla: 0.648 ± 0.72
0.0AsnCys: 0.0 ± 0.0
1.297AsnAsp: 1.297 ± 0.621
1.621AsnGlu: 1.621 ± 0.319
1.621AsnPhe: 1.621 ± 0.272
5.835AsnGly: 5.835 ± 1.841
0.0AsnHis: 0.0 ± 0.0
1.945AsnIle: 1.945 ± 1.085
3.89AsnLys: 3.89 ± 0.652
1.945AsnLeu: 1.945 ± 0.676
0.324AsnMet: 0.324 ± 0.195
1.621AsnAsn: 1.621 ± 0.683
2.593AsnPro: 2.593 ± 0.427
0.648AsnGln: 0.648 ± 0.42
3.241AsnArg: 3.241 ± 1.352
2.917AsnSer: 2.917 ± 0.655
2.269AsnThr: 2.269 ± 0.72
2.917AsnVal: 2.917 ± 0.266
1.621AsnTrp: 1.621 ± 0.356
2.269AsnTyr: 2.269 ± 0.807
0.0AsnXaa: 0.0 ± 0.0
Pro
4.214ProAla: 4.214 ± 1.426
1.297ProCys: 1.297 ± 0.431
0.972ProAsp: 0.972 ± 0.392
2.593ProGlu: 2.593 ± 1.088
1.297ProPhe: 1.297 ± 0.687
5.511ProGly: 5.511 ± 1.03
2.917ProHis: 2.917 ± 0.501
1.621ProIle: 1.621 ± 0.319
2.593ProLys: 2.593 ± 0.753
4.214ProLeu: 4.214 ± 0.433
1.621ProMet: 1.621 ± 0.356
1.621ProAsn: 1.621 ± 0.617
10.373ProPro: 10.373 ± 3.263
5.835ProGln: 5.835 ± 0.964
6.807ProArg: 6.807 ± 1.002
5.186ProSer: 5.186 ± 1.238
4.214ProThr: 4.214 ± 1.598
6.159ProVal: 6.159 ± 0.8
0.0ProTrp: 0.0 ± 0.0
0.324ProTyr: 0.324 ± 0.21
0.0ProXaa: 0.0 ± 0.0
Gln
1.945GlnAla: 1.945 ± 0.597
0.0GlnCys: 0.0 ± 0.0
1.621GlnAsp: 1.621 ± 0.455
2.269GlnGlu: 2.269 ± 0.371
1.297GlnPhe: 1.297 ± 0.462
3.241GlnGly: 3.241 ± 1.268
0.648GlnHis: 0.648 ± 0.269
1.945GlnIle: 1.945 ± 0.765
2.917GlnLys: 2.917 ± 0.546
3.89GlnLeu: 3.89 ± 0.591
0.648GlnMet: 0.648 ± 0.415
1.621GlnAsn: 1.621 ± 0.736
1.297GlnPro: 1.297 ± 0.414
1.297GlnGln: 1.297 ± 0.218
3.89GlnArg: 3.89 ± 0.853
4.214GlnSer: 4.214 ± 0.659
1.945GlnThr: 1.945 ± 0.725
3.566GlnVal: 3.566 ± 0.797
0.648GlnTrp: 0.648 ± 0.483
0.324GlnTyr: 0.324 ± 0.21
0.0GlnXaa: 0.0 ± 0.0
Arg
4.538ArgAla: 4.538 ± 1.204
0.972ArgCys: 0.972 ± 0.393
2.593ArgAsp: 2.593 ± 0.567
3.566ArgGlu: 3.566 ± 1.303
5.835ArgPhe: 5.835 ± 1.132
4.538ArgGly: 4.538 ± 0.791
0.324ArgHis: 0.324 ± 0.21
2.593ArgIle: 2.593 ± 0.584
2.593ArgLys: 2.593 ± 0.359
6.159ArgLeu: 6.159 ± 1.237
0.0ArgMet: 0.0 ± 0.0
5.186ArgAsn: 5.186 ± 1.989
2.917ArgPro: 2.917 ± 0.857
1.945ArgGln: 1.945 ± 0.315
11.994ArgArg: 11.994 ± 3.392
3.566ArgSer: 3.566 ± 0.958
3.241ArgThr: 3.241 ± 0.422
4.214ArgVal: 4.214 ± 1.068
0.972ArgTrp: 0.972 ± 0.374
1.945ArgTyr: 1.945 ± 0.413
0.0ArgXaa: 0.0 ± 0.0
Ser
4.538SerAla: 4.538 ± 1.164
1.945SerCys: 1.945 ± 0.749
1.621SerAsp: 1.621 ± 0.571
9.076SerGlu: 9.076 ± 1.49
2.269SerPhe: 2.269 ± 0.609
7.455SerGly: 7.455 ± 1.029
3.241SerHis: 3.241 ± 0.608
3.241SerIle: 3.241 ± 1.811
7.131SerLys: 7.131 ± 2.169
8.752SerLeu: 8.752 ± 1.253
1.297SerMet: 1.297 ± 0.357
2.593SerAsn: 2.593 ± 0.741
4.214SerPro: 4.214 ± 1.237
3.89SerGln: 3.89 ± 1.046
7.131SerArg: 7.131 ± 0.649
11.345SerSer: 11.345 ± 1.497
4.862SerThr: 4.862 ± 1.074
5.511SerVal: 5.511 ± 0.662
2.917SerTrp: 2.917 ± 0.481
2.593SerTyr: 2.593 ± 0.543
0.0SerXaa: 0.0 ± 0.0
Thr
3.241ThrAla: 3.241 ± 0.754
1.297ThrCys: 1.297 ± 0.538
1.945ThrAsp: 1.945 ± 0.373
2.917ThrGlu: 2.917 ± 0.481
5.186ThrPhe: 5.186 ± 0.947
5.186ThrGly: 5.186 ± 1.09
0.648ThrHis: 0.648 ± 0.362
3.566ThrIle: 3.566 ± 0.972
2.269ThrLys: 2.269 ± 0.76
3.241ThrLeu: 3.241 ± 0.532
1.621ThrMet: 1.621 ± 0.425
1.297ThrAsn: 1.297 ± 0.414
6.159ThrPro: 6.159 ± 1.27
0.972ThrGln: 0.972 ± 0.406
2.917ThrArg: 2.917 ± 0.587
6.159ThrSer: 6.159 ± 0.55
5.835ThrThr: 5.835 ± 1.2
5.186ThrVal: 5.186 ± 0.332
0.648ThrTrp: 0.648 ± 0.454
0.648ThrTyr: 0.648 ± 0.421
0.0ThrXaa: 0.0 ± 0.0
Val
5.186ValAla: 5.186 ± 0.895
0.648ValCys: 0.648 ± 0.269
1.621ValAsp: 1.621 ± 0.693
6.159ValGlu: 6.159 ± 0.309
1.621ValPhe: 1.621 ± 0.548
4.214ValGly: 4.214 ± 0.774
0.648ValHis: 0.648 ± 0.269
3.241ValIle: 3.241 ± 0.922
3.241ValLys: 3.241 ± 0.603
4.862ValLeu: 4.862 ± 1.584
1.621ValMet: 1.621 ± 0.617
2.593ValAsn: 2.593 ± 0.723
5.186ValPro: 5.186 ± 1.281
2.593ValGln: 2.593 ± 0.524
2.269ValArg: 2.269 ± 0.542
8.104ValSer: 8.104 ± 0.987
4.538ValThr: 4.538 ± 0.765
6.159ValVal: 6.159 ± 0.869
0.324ValTrp: 0.324 ± 0.36
0.972ValTyr: 0.972 ± 0.393
0.0ValXaa: 0.0 ± 0.0
Trp
0.972TrpAla: 0.972 ± 0.374
0.0TrpCys: 0.0 ± 0.0
0.972TrpAsp: 0.972 ± 0.813
1.945TrpGlu: 1.945 ± 0.413
0.972TrpPhe: 0.972 ± 0.167
0.972TrpGly: 0.972 ± 0.491
0.972TrpHis: 0.972 ± 0.539
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.269TrpLeu: 2.269 ± 0.541
1.945TrpMet: 1.945 ± 0.413
0.0TrpAsn: 0.0 ± 0.0
1.297TrpPro: 1.297 ± 0.218
0.648TrpGln: 0.648 ± 0.269
0.648TrpArg: 0.648 ± 0.42
2.593TrpSer: 2.593 ± 0.727
2.269TrpThr: 2.269 ± 0.422
0.972TrpVal: 0.972 ± 0.374
0.0TrpTrp: 0.0 ± 0.0
0.324TrpTyr: 0.324 ± 0.304
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.297TyrAla: 1.297 ± 0.364
0.648TyrCys: 0.648 ± 0.449
1.297TyrAsp: 1.297 ± 0.361
1.297TyrGlu: 1.297 ± 0.823
0.324TyrPhe: 0.324 ± 0.21
1.621TyrGly: 1.621 ± 0.272
1.621TyrHis: 1.621 ± 0.474
0.972TyrIle: 0.972 ± 0.47
2.269TyrLys: 2.269 ± 0.743
2.593TyrLeu: 2.593 ± 0.5
0.0TyrMet: 0.0 ± 0.0
0.972TyrAsn: 0.972 ± 0.392
1.945TyrPro: 1.945 ± 0.62
0.972TyrGln: 0.972 ± 0.458
2.269TyrArg: 2.269 ± 0.799
1.297TyrSer: 1.297 ± 0.361
0.972TyrThr: 0.972 ± 0.813
0.648TyrVal: 0.648 ± 0.269
0.0TyrTrp: 0.0 ± 0.0
0.324TyrTyr: 0.324 ± 0.21
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.324XaaVal: 0.324 ± 0.271
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3086 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski