Amino acid dipepetide frequency for Marinicaulis flavus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.817AlaAla: 18.817 ± 0.183	1.159AlaCys: 1.159 ± 0.03	7.25AlaAsp: 7.25 ± 0.078	8.158AlaGlu: 8.158 ± 0.093	5.236AlaPhe: 5.236 ± 0.065	11.133AlaGly: 11.133 ± 0.114	2.292AlaHis: 2.292 ± 0.047	5.881AlaIle: 5.881 ± 0.071	4.845AlaLys: 4.845 ± 0.065	13.235AlaLeu: 13.235 ± 0.126	3.36AlaMet: 3.36 ± 0.058	3.043AlaAsn: 3.043 ± 0.05	6.977AlaPro: 6.977 ± 0.088	3.805AlaGln: 3.805 ± 0.054	8.541AlaArg: 8.541 ± 0.094	6.752AlaSer: 6.752 ± 0.077	4.804AlaThr: 4.804 ± 0.066	8.319AlaVal: 8.319 ± 0.085	1.393AlaTrp: 1.393 ± 0.034	2.993AlaTyr: 2.993 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	1.237CysAla: 1.237 ± 0.034	0.114CysCys: 0.114 ± 0.01	0.554CysAsp: 0.554 ± 0.02	0.515CysGlu: 0.515 ± 0.02	0.334CysPhe: 0.334 ± 0.013	0.897CysGly: 0.897 ± 0.028	0.216CysHis: 0.216 ± 0.018	0.37CysIle: 0.37 ± 0.018	0.248CysLys: 0.248 ± 0.013	0.745CysLeu: 0.745 ± 0.026	0.175CysMet: 0.175 ± 0.01	0.235CysAsn: 0.235 ± 0.013	0.437CysPro: 0.437 ± 0.02	0.189CysGln: 0.189 ± 0.013	0.546CysArg: 0.546 ± 0.021	0.47CysSer: 0.47 ± 0.019	0.367CysThr: 0.367 ± 0.017	0.619CysVal: 0.619 ± 0.022	0.106CysTrp: 0.106 ± 0.008	0.194CysTyr: 0.194 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.942AspAla: 7.942 ± 0.096	0.542AspCys: 0.542 ± 0.021	3.933AspAsp: 3.933 ± 0.067	4.441AspGlu: 4.441 ± 0.065	2.67AspPhe: 2.67 ± 0.049	5.686AspGly: 5.686 ± 0.092	1.24AspHis: 1.24 ± 0.031	3.576AspIle: 3.576 ± 0.05	2.41AspLys: 2.41 ± 0.039	5.761AspLeu: 5.761 ± 0.068	1.513AspMet: 1.513 ± 0.032	1.71AspAsn: 1.71 ± 0.036	3.488AspPro: 3.488 ± 0.05	1.529AspGln: 1.529 ± 0.038	3.944AspArg: 3.944 ± 0.062	2.303AspSer: 2.303 ± 0.048	2.201AspThr: 2.201 ± 0.046	4.212AspVal: 4.212 ± 0.058	1.058AspTrp: 1.058 ± 0.026	2.077AspTyr: 2.077 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	8.535GluAla: 8.535 ± 0.095	0.436GluCys: 0.436 ± 0.021	4.084GluAsp: 4.084 ± 0.061	4.737GluGlu: 4.737 ± 0.071	2.194GluPhe: 2.194 ± 0.042	5.11GluGly: 5.11 ± 0.065	1.107GluHis: 1.107 ± 0.029	4.023GluIle: 4.023 ± 0.058	3.588GluLys: 3.588 ± 0.055	5.155GluLeu: 5.155 ± 0.062	1.663GluMet: 1.663 ± 0.035	2.382GluAsn: 2.382 ± 0.049	2.827GluPro: 2.827 ± 0.042	1.97GluGln: 1.97 ± 0.046	4.908GluArg: 4.908 ± 0.073	2.762GluSer: 2.762 ± 0.046	4.656GluThr: 4.656 ± 0.069	3.418GluVal: 3.418 ± 0.053	0.782GluTrp: 0.782 ± 0.025	1.314GluTyr: 1.314 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	5.042PheAla: 5.042 ± 0.073	0.429PheCys: 0.429 ± 0.019	3.11PheAsp: 3.11 ± 0.049	2.704PheGlu: 2.704 ± 0.047	1.862PhePhe: 1.862 ± 0.044	3.731PheGly: 3.731 ± 0.058	0.843PheHis: 0.843 ± 0.024	2.082PheIle: 2.082 ± 0.042	1.389PheLys: 1.389 ± 0.031	3.829PheLeu: 3.829 ± 0.058	0.888PheMet: 0.888 ± 0.022	1.327PheAsn: 1.327 ± 0.032	1.655PhePro: 1.655 ± 0.034	1.019PheGln: 1.019 ± 0.029	2.154PheArg: 2.154 ± 0.034	2.778PheSer: 2.778 ± 0.048	2.192PheThr: 2.192 ± 0.04	2.687PheVal: 2.687 ± 0.046	0.576PheTrp: 0.576 ± 0.022	1.156PheTyr: 1.156 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	11.569GlyAla: 11.569 ± 0.113	0.757GlyCys: 0.757 ± 0.023	5.344GlyAsp: 5.344 ± 0.079	6.051GlyGlu: 6.051 ± 0.074	3.929GlyPhe: 3.929 ± 0.059	8.045GlyGly: 8.045 ± 0.107	1.562GlyHis: 1.562 ± 0.036	3.005GlyIle: 3.005 ± 0.053	3.322GlyLys: 3.322 ± 0.054	8.161GlyLeu: 8.161 ± 0.084	1.928GlyMet: 1.928 ± 0.042	1.862GlyAsn: 1.862 ± 0.045	3.65GlyPro: 3.65 ± 0.047	2.105GlyGln: 2.105 ± 0.042	5.454GlyArg: 5.454 ± 0.073	3.96GlySer: 3.96 ± 0.056	3.129GlyThr: 3.129 ± 0.053	7.551GlyVal: 7.551 ± 0.087	1.307GlyTrp: 1.307 ± 0.032	2.396GlyTyr: 2.396 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.101HisAla: 2.101 ± 0.046	0.239HisCys: 0.239 ± 0.014	1.118HisAsp: 1.118 ± 0.028	1.134HisGlu: 1.134 ± 0.031	0.82HisPhe: 0.82 ± 0.025	1.658HisGly: 1.658 ± 0.037	0.485HisHis: 0.485 ± 0.019	0.933HisIle: 0.933 ± 0.026	0.637HisLys: 0.637 ± 0.023	1.758HisLeu: 1.758 ± 0.038	0.458HisMet: 0.458 ± 0.02	0.47HisAsn: 0.47 ± 0.016	1.161HisPro: 1.161 ± 0.032	0.51HisGln: 0.51 ± 0.019	1.111HisArg: 1.111 ± 0.031	0.894HisSer: 0.894 ± 0.029	0.689HisThr: 0.689 ± 0.021	1.301HisVal: 1.301 ± 0.028	0.325HisTrp: 0.325 ± 0.015	0.592HisTyr: 0.592 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.188IleAla: 7.188 ± 0.073	0.485IleCys: 0.485 ± 0.019	3.86IleAsp: 3.86 ± 0.048	3.834IleGlu: 3.834 ± 0.049	1.974IlePhe: 1.974 ± 0.042	4.61IleGly: 4.61 ± 0.072	0.838IleHis: 0.838 ± 0.023	2.489IleIle: 2.489 ± 0.046	1.685IleLys: 1.685 ± 0.034	4.342IleLeu: 4.342 ± 0.058	1.012IleMet: 1.012 ± 0.03	1.49IleAsn: 1.49 ± 0.034	2.064IlePro: 2.064 ± 0.033	1.085IleGln: 1.085 ± 0.032	3.017IleArg: 3.017 ± 0.042	3.059IleSer: 3.059 ± 0.051	2.346IleThr: 2.346 ± 0.041	3.949IleVal: 3.949 ± 0.057	0.534IleTrp: 0.534 ± 0.019	1.284IleTyr: 1.284 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	5.137LysAla: 5.137 ± 0.073	0.213LysCys: 0.213 ± 0.012	2.428LysAsp: 2.428 ± 0.045	2.446LysGlu: 2.446 ± 0.046	1.23LysPhe: 1.23 ± 0.033	3.083LysGly: 3.083 ± 0.053	0.71LysHis: 0.71 ± 0.025	2.234LysIle: 2.234 ± 0.038	2.269LysLys: 2.269 ± 0.064	3.638LysLeu: 3.638 ± 0.056	0.916LysMet: 0.916 ± 0.025	1.275LysAsn: 1.275 ± 0.032	2.337LysPro: 2.337 ± 0.044	1.144LysGln: 1.144 ± 0.028	3.03LysArg: 3.03 ± 0.052	2.345LysSer: 2.345 ± 0.046	2.756LysThr: 2.756 ± 0.045	2.185LysVal: 2.185 ± 0.041	0.455LysTrp: 0.455 ± 0.019	0.77LysTyr: 0.77 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	12.245LeuAla: 12.245 ± 0.117	0.87LeuCys: 0.87 ± 0.029	5.825LeuAsp: 5.825 ± 0.068	5.651LeuGlu: 5.651 ± 0.071	3.912LeuPhe: 3.912 ± 0.066	7.453LeuGly: 7.453 ± 0.081	1.634LeuHis: 1.634 ± 0.034	5.026LeuIle: 5.026 ± 0.066	4.392LeuLys: 4.392 ± 0.07	7.839LeuLeu: 7.839 ± 0.09	2.215LeuMet: 2.215 ± 0.042	2.901LeuAsn: 2.901 ± 0.053	4.537LeuPro: 4.537 ± 0.062	2.402LeuGln: 2.402 ± 0.043	5.784LeuArg: 5.784 ± 0.08	6.592LeuSer: 6.592 ± 0.075	5.146LeuThr: 5.146 ± 0.058	5.852LeuVal: 5.852 ± 0.075	1.111LeuTrp: 1.111 ± 0.03	2.297LeuTyr: 2.297 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.946MetAla: 2.946 ± 0.044	0.163MetCys: 0.163 ± 0.009	1.101MetAsp: 1.101 ± 0.029	1.282MetGlu: 1.282 ± 0.029	0.764MetPhe: 0.764 ± 0.021	1.694MetGly: 1.694 ± 0.038	0.388MetHis: 0.388 ± 0.014	1.31MetIle: 1.31 ± 0.029	1.262MetLys: 1.262 ± 0.03	2.232MetLeu: 2.232 ± 0.042	0.638MetMet: 0.638 ± 0.025	0.811MetAsn: 0.811 ± 0.025	1.249MetPro: 1.249 ± 0.03	0.71MetGln: 0.71 ± 0.022	1.902MetArg: 1.902 ± 0.034	1.622MetSer: 1.622 ± 0.031	1.863MetThr: 1.863 ± 0.038	1.289MetVal: 1.289 ± 0.03	0.221MetTrp: 0.221 ± 0.013	0.294MetTyr: 0.294 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.697AsnAla: 3.697 ± 0.052	0.252AsnCys: 0.252 ± 0.014	1.749AsnAsp: 1.749 ± 0.037	1.659AsnGlu: 1.659 ± 0.035	1.203AsnPhe: 1.203 ± 0.028	2.651AsnGly: 2.651 ± 0.053	0.517AsnHis: 0.517 ± 0.02	1.666AsnIle: 1.666 ± 0.037	0.931AsnLys: 0.931 ± 0.028	2.71AsnLeu: 2.71 ± 0.048	0.622AsnMet: 0.622 ± 0.023	0.873AsnAsn: 0.873 ± 0.029	1.819AsnPro: 1.819 ± 0.04	0.75AsnGln: 0.75 ± 0.023	1.783AsnArg: 1.783 ± 0.042	1.384AsnSer: 1.384 ± 0.034	1.284AsnThr: 1.284 ± 0.034	2.075AsnVal: 2.075 ± 0.038	0.442AsnTrp: 0.442 ± 0.019	0.818AsnTyr: 0.818 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	6.08ProAla: 6.08 ± 0.067	0.36ProCys: 0.36 ± 0.017	3.765ProAsp: 3.765 ± 0.056	4.099ProGlu: 4.099 ± 0.056	2.053ProPhe: 2.053 ± 0.037	4.424ProGly: 4.424 ± 0.06	0.964ProHis: 0.964 ± 0.029	2.12ProIle: 2.12 ± 0.036	1.853ProLys: 1.853 ± 0.04	4.385ProLeu: 4.385 ± 0.047	1.062ProMet: 1.062 ± 0.026	1.35ProAsn: 1.35 ± 0.029	2.528ProPro: 2.528 ± 0.047	1.524ProGln: 1.524 ± 0.033	2.56ProArg: 2.56 ± 0.04	2.703ProSer: 2.703 ± 0.044	1.982ProThr: 1.982 ± 0.036	3.914ProVal: 3.914 ± 0.048	0.587ProTrp: 0.587 ± 0.02	1.271ProTyr: 1.271 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.218GlnAla: 3.218 ± 0.045	0.225GlnCys: 0.225 ± 0.011	1.466GlnAsp: 1.466 ± 0.036	1.631GlnGlu: 1.631 ± 0.037	1.08GlnPhe: 1.08 ± 0.027	2.097GlnGly: 2.097 ± 0.038	0.508GlnHis: 0.508 ± 0.018	1.572GlnIle: 1.572 ± 0.03	1.216GlnLys: 1.216 ± 0.031	2.365GlnLeu: 2.365 ± 0.043	0.751GlnMet: 0.751 ± 0.019	0.942GlnAsn: 0.942 ± 0.028	1.334GlnPro: 1.334 ± 0.029	0.796GlnGln: 0.796 ± 0.024	1.907GlnArg: 1.907 ± 0.031	1.759GlnSer: 1.759 ± 0.039	1.684GlnThr: 1.684 ± 0.038	1.572GlnVal: 1.572 ± 0.04	0.379GlnTrp: 0.379 ± 0.017	0.723GlnTyr: 0.723 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	7.86ArgAla: 7.86 ± 0.085	0.491ArgCys: 0.491 ± 0.021	3.756ArgAsp: 3.756 ± 0.05	4.389ArgGlu: 4.389 ± 0.068	2.904ArgPhe: 2.904 ± 0.045	4.366ArgGly: 4.366 ± 0.058	1.283ArgHis: 1.283 ± 0.031	3.74ArgIle: 3.74 ± 0.05	2.81ArgLys: 2.81 ± 0.058	7.108ArgLeu: 7.108 ± 0.088	1.597ArgMet: 1.597 ± 0.039	1.968ArgAsn: 1.968 ± 0.041	3.036ArgPro: 3.036 ± 0.047	2.104ArgGln: 2.104 ± 0.045	5.299ArgArg: 5.299 ± 0.079	3.216ArgSer: 3.216 ± 0.051	2.907ArgThr: 2.907 ± 0.052	4.007ArgVal: 4.007 ± 0.05	0.882ArgTrp: 0.882 ± 0.027	1.877ArgTyr: 1.877 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.626SerAla: 6.626 ± 0.079	0.486SerCys: 0.486 ± 0.022	3.322SerAsp: 3.322 ± 0.051	3.22SerGlu: 3.22 ± 0.048	2.52SerPhe: 2.52 ± 0.043	5.454SerGly: 5.454 ± 0.075	0.988SerHis: 0.988 ± 0.026	2.803SerIle: 2.803 ± 0.049	1.934SerLys: 1.934 ± 0.035	5.379SerLeu: 5.379 ± 0.068	1.332SerMet: 1.332 ± 0.028	1.504SerAsn: 1.504 ± 0.033	2.935SerPro: 2.935 ± 0.048	1.525SerGln: 1.525 ± 0.036	3.263SerArg: 3.263 ± 0.041	3.079SerSer: 3.079 ± 0.054	2.362SerThr: 2.362 ± 0.047	3.928SerVal: 3.928 ± 0.053	0.766SerTrp: 0.766 ± 0.025	1.539SerTyr: 1.539 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	5.854ThrAla: 5.854 ± 0.071	0.377ThrCys: 0.377 ± 0.017	2.948ThrAsp: 2.948 ± 0.05	2.643ThrGlu: 2.643 ± 0.044	1.834ThrPhe: 1.834 ± 0.037	4.864ThrGly: 4.864 ± 0.057	0.917ThrHis: 0.917 ± 0.027	2.593ThrIle: 2.593 ± 0.046	1.617ThrLys: 1.617 ± 0.036	5.058ThrLeu: 5.058 ± 0.063	0.993ThrMet: 0.993 ± 0.027	1.296ThrAsn: 1.296 ± 0.033	3.349ThrPro: 3.349 ± 0.057	1.366ThrGln: 1.366 ± 0.035	2.817ThrArg: 2.817 ± 0.044	2.527ThrSer: 2.527 ± 0.053	2.397ThrThr: 2.397 ± 0.051	3.612ThrVal: 3.612 ± 0.051	0.487ThrTrp: 0.487 ± 0.018	1.287ThrTyr: 1.287 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	7.584ValAla: 7.584 ± 0.073	0.621ValCys: 0.621 ± 0.022	4.143ValAsp: 4.143 ± 0.057	4.616ValGlu: 4.616 ± 0.053	3.202ValPhe: 3.202 ± 0.054	4.831ValGly: 4.831 ± 0.065	1.178ValHis: 1.178 ± 0.029	4.018ValIle: 4.018 ± 0.055	2.837ValLys: 2.837 ± 0.042	6.155ValLeu: 6.155 ± 0.073	1.785ValMet: 1.785 ± 0.035	2.258ValAsn: 2.258 ± 0.046	2.557ValPro: 2.557 ± 0.04	1.648ValGln: 1.648 ± 0.04	4.168ValArg: 4.168 ± 0.049	4.517ValSer: 4.517 ± 0.051	4.159ValThr: 4.159 ± 0.062	4.752ValVal: 4.752 ± 0.056	0.907ValTrp: 0.907 ± 0.026	1.762ValTyr: 1.762 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.273TrpAla: 1.273 ± 0.035	0.099TrpCys: 0.099 ± 0.008	0.633TrpAsp: 0.633 ± 0.021	0.615TrpGlu: 0.615 ± 0.021	0.553TrpPhe: 0.553 ± 0.019	0.898TrpGly: 0.898 ± 0.027	0.224TrpHis: 0.224 ± 0.012	0.634TrpIle: 0.634 ± 0.021	0.526TrpLys: 0.526 ± 0.021	1.413TrpLeu: 1.413 ± 0.036	0.336TrpMet: 0.336 ± 0.017	0.447TrpAsn: 0.447 ± 0.017	0.609TrpPro: 0.609 ± 0.023	0.304TrpGln: 0.304 ± 0.014	1.558TrpArg: 1.558 ± 0.037	0.838TrpSer: 0.838 ± 0.028	0.82TrpThr: 0.82 ± 0.028	0.676TrpVal: 0.676 ± 0.025	0.188TrpTrp: 0.188 ± 0.012	0.258TrpTyr: 0.258 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.04TyrAla: 3.04 ± 0.052	0.252TyrCys: 0.252 ± 0.013	1.846TyrAsp: 1.846 ± 0.048	1.826TyrGlu: 1.826 ± 0.039	1.176TyrPhe: 1.176 ± 0.033	2.406TyrGly: 2.406 ± 0.04	0.5TyrHis: 0.5 ± 0.019	1.072TyrIle: 1.072 ± 0.032	0.832TyrLys: 0.832 ± 0.022	2.417TyrLeu: 2.417 ± 0.042	0.496TyrMet: 0.496 ± 0.019	0.743TyrAsn: 0.743 ± 0.026	1.032TyrPro: 1.032 ± 0.034	0.738TyrGln: 0.738 ± 0.024	1.855TyrArg: 1.855 ± 0.038	1.405TyrSer: 1.405 ± 0.036	1.093TyrThr: 1.093 ± 0.031	1.778TyrVal: 1.778 ± 0.034	0.395TyrTrp: 0.395 ± 0.017	0.848TyrTyr: 0.848 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4433 proteins (1441813 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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