Amino acid dipepetide frequency for Theileria equi strain WA

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	2.741AlaAla: 2.741 ± 0.048	0.878AlaCys: 0.878 ± 0.018	2.419AlaAsp: 2.419 ± 0.031	2.928AlaGlu: 2.928 ± 0.037	2.185AlaPhe: 2.185 ± 0.032	2.779AlaGly: 2.779 ± 0.043	1.094AlaHis: 1.094 ± 0.02	3.547AlaIle: 3.547 ± 0.039	3.887AlaLys: 3.887 ± 0.047	5.016AlaLeu: 5.016 ± 0.056	1.006AlaMet: 1.006 ± 0.023	2.421AlaAsn: 2.421 ± 0.032	2.027AlaPro: 2.027 ± 0.03	1.489AlaGln: 1.489 ± 0.025	2.05AlaArg: 2.05 ± 0.032	4.26AlaSer: 4.26 ± 0.044	2.974AlaThr: 2.974 ± 0.037	3.127AlaVal: 3.127 ± 0.04	0.386AlaTrp: 0.386 ± 0.013	1.723AlaTyr: 1.723 ± 0.027	0.0AlaXaa: 0.0 ± 0.0
Cys	0.81CysAla: 0.81 ± 0.018	0.504CysCys: 0.504 ± 0.02	0.976CysAsp: 0.976 ± 0.018	0.941CysGlu: 0.941 ± 0.019	0.775CysPhe: 0.775 ± 0.015	1.186CysGly: 1.186 ± 0.023	0.446CysHis: 0.446 ± 0.013	1.396CysIle: 1.396 ± 0.026	1.688CysLys: 1.688 ± 0.029	1.671CysLeu: 1.671 ± 0.028	0.389CysMet: 0.389 ± 0.013	1.062CysAsn: 1.062 ± 0.018	0.683CysPro: 0.683 ± 0.021	0.507CysGln: 0.507 ± 0.015	0.915CysArg: 0.915 ± 0.021	1.627CysSer: 1.627 ± 0.028	1.308CysThr: 1.308 ± 0.023	0.934CysVal: 0.934 ± 0.019	0.143CysTrp: 0.143 ± 0.008	0.661CysTyr: 0.661 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	2.991AspAla: 2.991 ± 0.036	0.917AspCys: 0.917 ± 0.02	4.091AspAsp: 4.091 ± 0.049	4.607AspGlu: 4.607 ± 0.055	2.377AspPhe: 2.377 ± 0.032	4.539AspGly: 4.539 ± 0.062	1.234AspHis: 1.234 ± 0.019	4.671AspIle: 4.671 ± 0.043	4.328AspLys: 4.328 ± 0.044	5.202AspLeu: 5.202 ± 0.045	1.05AspMet: 1.05 ± 0.021	3.069AspAsn: 3.069 ± 0.041	2.557AspPro: 2.557 ± 0.033	1.485AspGln: 1.485 ± 0.022	2.271AspArg: 2.271 ± 0.032	5.139AspSer: 5.139 ± 0.051	3.329AspThr: 3.329 ± 0.044	4.054AspVal: 4.054 ± 0.047	0.471AspTrp: 0.471 ± 0.013	2.264AspTyr: 2.264 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	3.333GluAla: 3.333 ± 0.043	1.113GluCys: 1.113 ± 0.021	4.386GluAsp: 4.386 ± 0.051	5.526GluGlu: 5.526 ± 0.077	2.557GluPhe: 2.557 ± 0.034	3.25GluGly: 3.25 ± 0.041	1.682GluHis: 1.682 ± 0.029	4.17GluIle: 4.17 ± 0.043	5.204GluLys: 5.204 ± 0.058	5.711GluLeu: 5.711 ± 0.052	1.298GluMet: 1.298 ± 0.025	4.087GluAsn: 4.087 ± 0.047	2.305GluPro: 2.305 ± 0.041	1.942GluGln: 1.942 ± 0.031	2.947GluArg: 2.947 ± 0.035	5.415GluSer: 5.415 ± 0.054	3.583GluThr: 3.583 ± 0.043	3.695GluVal: 3.695 ± 0.039	0.753GluTrp: 0.753 ± 0.02	2.631GluTyr: 2.631 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	2.0PheAla: 2.0 ± 0.032	0.88PheCys: 0.88 ± 0.017	2.612PheAsp: 2.612 ± 0.031	2.604PheGlu: 2.604 ± 0.033	1.892PhePhe: 1.892 ± 0.032	2.621PheGly: 2.621 ± 0.045	0.929PheHis: 0.929 ± 0.018	2.977PheIle: 2.977 ± 0.039	3.156PheLys: 3.156 ± 0.038	3.816PheLeu: 3.816 ± 0.056	0.943PheMet: 0.943 ± 0.021	2.26PheAsn: 2.26 ± 0.029	1.529PhePro: 1.529 ± 0.024	1.109PheGln: 1.109 ± 0.021	1.763PheArg: 1.763 ± 0.027	3.728PheSer: 3.728 ± 0.045	2.629PheThr: 2.629 ± 0.035	2.875PheVal: 2.875 ± 0.042	0.542PheTrp: 0.542 ± 0.015	2.025PheTyr: 2.025 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	2.852GlyAla: 2.852 ± 0.038	0.899GlyCys: 0.899 ± 0.018	3.796GlyAsp: 3.796 ± 0.045	3.445GlyGlu: 3.445 ± 0.043	2.554GlyPhe: 2.554 ± 0.036	4.156GlyGly: 4.156 ± 0.065	1.282GlyHis: 1.282 ± 0.023	4.179GlyIle: 4.179 ± 0.046	4.5GlyLys: 4.5 ± 0.052	4.608GlyLeu: 4.608 ± 0.052	1.043GlyMet: 1.043 ± 0.025	3.506GlyAsn: 3.506 ± 0.042	1.986GlyPro: 1.986 ± 0.036	1.603GlyGln: 1.603 ± 0.027	2.426GlyArg: 2.426 ± 0.037	5.246GlySer: 5.246 ± 0.061	3.802GlyThr: 3.802 ± 0.044	3.352GlyVal: 3.352 ± 0.037	0.683GlyTrp: 0.683 ± 0.017	2.48GlyTyr: 2.48 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	1.12HisAla: 1.12 ± 0.022	0.445HisCys: 0.445 ± 0.012	1.232HisAsp: 1.232 ± 0.022	1.323HisGlu: 1.323 ± 0.025	1.098HisPhe: 1.098 ± 0.023	1.422HisGly: 1.422 ± 0.025	0.551HisHis: 0.551 ± 0.015	1.723HisIle: 1.723 ± 0.025	1.696HisLys: 1.696 ± 0.028	2.115HisLeu: 2.115 ± 0.031	0.43HisMet: 0.43 ± 0.013	1.244HisAsn: 1.244 ± 0.023	0.951HisPro: 0.951 ± 0.017	0.573HisGln: 0.573 ± 0.015	1.061HisArg: 1.061 ± 0.021	2.001HisSer: 2.001 ± 0.027	1.464HisThr: 1.464 ± 0.027	1.488HisVal: 1.488 ± 0.025	0.224HisTrp: 0.224 ± 0.01	0.94HisTyr: 0.94 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	3.395IleAla: 3.395 ± 0.04	1.325IleCys: 1.325 ± 0.026	4.088IleAsp: 4.088 ± 0.04	3.873IleGlu: 3.873 ± 0.048	2.977IlePhe: 2.977 ± 0.038	3.269IleGly: 3.269 ± 0.042	1.636IleHis: 1.636 ± 0.025	4.19IleIle: 4.19 ± 0.054	5.141IleLys: 5.141 ± 0.052	6.704IleLeu: 6.704 ± 0.058	1.268IleMet: 1.268 ± 0.022	3.595IleAsn: 3.595 ± 0.038	3.196IlePro: 3.196 ± 0.04	2.011IleGln: 2.011 ± 0.032	2.816IleArg: 2.816 ± 0.037	6.367IleSer: 6.367 ± 0.063	4.084IleThr: 4.084 ± 0.042	3.989IleVal: 3.989 ± 0.042	0.895IleTrp: 0.895 ± 0.019	2.828IleTyr: 2.828 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	3.487LysAla: 3.487 ± 0.037	1.525LysCys: 1.525 ± 0.029	4.914LysAsp: 4.914 ± 0.054	5.317LysGlu: 5.317 ± 0.06	2.918LysPhe: 2.918 ± 0.036	4.158LysGly: 4.158 ± 0.049	2.02LysHis: 2.02 ± 0.03	4.966LysIle: 4.966 ± 0.046	5.585LysLys: 5.585 ± 0.069	6.938LysLeu: 6.938 ± 0.063	1.425LysMet: 1.425 ± 0.024	4.424LysAsn: 4.424 ± 0.042	2.994LysPro: 2.994 ± 0.038	2.128LysGln: 2.128 ± 0.032	4.064LysArg: 4.064 ± 0.041	5.669LysSer: 5.669 ± 0.05	4.037LysThr: 4.037 ± 0.04	4.794LysVal: 4.794 ± 0.048	1.038LysTrp: 1.038 ± 0.023	3.183LysTyr: 3.183 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	4.606LeuAla: 4.606 ± 0.053	1.831LeuCys: 1.831 ± 0.03	6.002LeuAsp: 6.002 ± 0.057	6.193LeuGlu: 6.193 ± 0.06	4.111LeuPhe: 4.111 ± 0.061	4.501LeuGly: 4.501 ± 0.04	2.166LeuHis: 2.166 ± 0.029	5.37LeuIle: 5.37 ± 0.053	6.935LeuLys: 6.935 ± 0.064	9.361LeuLeu: 9.361 ± 0.089	1.805LeuMet: 1.805 ± 0.027	4.815LeuAsn: 4.815 ± 0.049	3.728LeuPro: 3.728 ± 0.042	3.059LeuGln: 3.059 ± 0.038	4.044LeuArg: 4.044 ± 0.049	8.273LeuSer: 8.273 ± 0.071	4.667LeuThr: 4.667 ± 0.042	5.702LeuVal: 5.702 ± 0.052	1.044LeuTrp: 1.044 ± 0.021	3.672LeuTyr: 3.672 ± 0.034	0.0LeuXaa: 0.0 ± 0.0
Met	1.12MetAla: 1.12 ± 0.023	0.319MetCys: 0.319 ± 0.011	1.433MetAsp: 1.433 ± 0.023	1.473MetGlu: 1.473 ± 0.027	0.817MetPhe: 0.817 ± 0.017	0.991MetGly: 0.991 ± 0.022	0.433MetHis: 0.433 ± 0.012	1.171MetIle: 1.171 ± 0.022	1.303MetLys: 1.303 ± 0.022	1.719MetLeu: 1.719 ± 0.028	0.405MetMet: 0.405 ± 0.014	1.068MetAsn: 1.068 ± 0.023	0.718MetPro: 0.718 ± 0.02	0.649MetGln: 0.649 ± 0.017	0.925MetArg: 0.925 ± 0.019	1.481MetSer: 1.481 ± 0.025	0.965MetThr: 0.965 ± 0.019	1.144MetVal: 1.144 ± 0.025	0.135MetTrp: 0.135 ± 0.008	0.666MetTyr: 0.666 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.744AsnAla: 2.744 ± 0.034	1.098AsnCys: 1.098 ± 0.023	3.238AsnAsp: 3.238 ± 0.038	3.461AsnGlu: 3.461 ± 0.041	2.246AsnPhe: 2.246 ± 0.028	3.962AsnGly: 3.962 ± 0.051	1.023AsnHis: 1.023 ± 0.019	4.272AsnIle: 4.272 ± 0.048	3.958AsnLys: 3.958 ± 0.039	4.704AsnLeu: 4.704 ± 0.048	1.114AsnMet: 1.114 ± 0.026	3.025AsnAsn: 3.025 ± 0.043	2.388AsnPro: 2.388 ± 0.032	1.33AsnGln: 1.33 ± 0.02	2.316AsnArg: 2.316 ± 0.035	4.439AsnSer: 4.439 ± 0.05	3.255AsnThr: 3.255 ± 0.041	3.866AsnVal: 3.866 ± 0.04	0.552AsnTrp: 0.552 ± 0.014	1.955AsnTyr: 1.955 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	1.891ProAla: 1.891 ± 0.033	0.539ProCys: 0.539 ± 0.016	2.24ProAsp: 2.24 ± 0.031	3.138ProGlu: 3.138 ± 0.044	1.747ProPhe: 1.747 ± 0.029	2.401ProGly: 2.401 ± 0.037	0.768ProHis: 0.768 ± 0.018	2.615ProIle: 2.615 ± 0.034	3.32ProLys: 3.32 ± 0.043	3.926ProLeu: 3.926 ± 0.041	0.656ProMet: 0.656 ± 0.02	2.183ProAsn: 2.183 ± 0.031	2.187ProPro: 2.187 ± 0.041	1.517ProGln: 1.517 ± 0.024	1.506ProArg: 1.506 ± 0.025	3.555ProSer: 3.555 ± 0.038	2.492ProThr: 2.492 ± 0.035	2.553ProVal: 2.553 ± 0.031	0.4ProTrp: 0.4 ± 0.013	1.3ProTyr: 1.3 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	1.396GlnAla: 1.396 ± 0.028	0.517GlnCys: 0.517 ± 0.013	1.729GlnAsp: 1.729 ± 0.027	2.173GlnGlu: 2.173 ± 0.033	1.157GlnPhe: 1.157 ± 0.022	1.666GlnGly: 1.666 ± 0.027	0.691GlnHis: 0.691 ± 0.016	1.99GlnIle: 1.99 ± 0.031	2.078GlnLys: 2.078 ± 0.033	2.756GlnLeu: 2.756 ± 0.033	0.637GlnMet: 0.637 ± 0.017	1.874GlnAsn: 1.874 ± 0.03	1.258GlnPro: 1.258 ± 0.025	1.065GlnGln: 1.065 ± 0.027	1.414GlnArg: 1.414 ± 0.025	2.246GlnSer: 2.246 ± 0.03	1.728GlnThr: 1.728 ± 0.028	1.781GlnVal: 1.781 ± 0.026	0.339GlnTrp: 0.339 ± 0.01	1.021GlnTyr: 1.021 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	2.044ArgAla: 2.044 ± 0.033	0.954ArgCys: 0.954 ± 0.017	2.556ArgAsp: 2.556 ± 0.028	2.742ArgGlu: 2.742 ± 0.038	2.066ArgPhe: 2.066 ± 0.03	2.394ArgGly: 2.394 ± 0.034	1.111ArgHis: 1.111 ± 0.019	3.447ArgIle: 3.447 ± 0.04	3.273ArgLys: 3.273 ± 0.045	4.237ArgLeu: 4.237 ± 0.04	0.974ArgMet: 0.974 ± 0.022	2.676ArgAsn: 2.676 ± 0.035	1.456ArgPro: 1.456 ± 0.027	1.303ArgGln: 1.303 ± 0.022	2.685ArgArg: 2.685 ± 0.054	3.348ArgSer: 3.348 ± 0.044	2.172ArgThr: 2.172 ± 0.029	2.79ArgVal: 2.79 ± 0.035	0.495ArgTrp: 0.495 ± 0.016	1.94ArgTyr: 1.94 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	4.209SerAla: 4.209 ± 0.036	1.519SerCys: 1.519 ± 0.028	5.018SerAsp: 5.018 ± 0.043	5.219SerGlu: 5.219 ± 0.058	3.688SerPhe: 3.688 ± 0.041	5.872SerGly: 5.872 ± 0.059	1.914SerHis: 1.914 ± 0.031	5.863SerIle: 5.863 ± 0.058	6.225SerLys: 6.225 ± 0.047	7.764SerLeu: 7.764 ± 0.074	1.491SerMet: 1.491 ± 0.026	4.488SerAsn: 4.488 ± 0.051	3.374SerPro: 3.374 ± 0.046	2.87SerGln: 2.87 ± 0.036	3.853SerArg: 3.853 ± 0.055	8.187SerSer: 8.187 ± 0.082	5.324SerThr: 5.324 ± 0.06	5.323SerVal: 5.323 ± 0.052	0.718SerTrp: 0.718 ± 0.015	2.83SerTyr: 2.83 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	2.788ThrAla: 2.788 ± 0.035	1.177ThrCys: 1.177 ± 0.023	2.994ThrAsp: 2.994 ± 0.036	3.471ThrGlu: 3.471 ± 0.047	2.828ThrPhe: 2.828 ± 0.034	3.521ThrGly: 3.521 ± 0.052	1.566ThrHis: 1.566 ± 0.028	4.064ThrIle: 4.064 ± 0.038	4.2ThrLys: 4.2 ± 0.045	5.891ThrLeu: 5.891 ± 0.049	0.968ThrMet: 0.968 ± 0.02	3.049ThrAsn: 3.049 ± 0.039	3.039ThrPro: 3.039 ± 0.045	1.709ThrGln: 1.709 ± 0.029	2.604ThrArg: 2.604 ± 0.03	5.257ThrSer: 5.257 ± 0.057	3.688ThrThr: 3.688 ± 0.06	3.69ThrVal: 3.69 ± 0.044	0.604ThrTrp: 0.604 ± 0.017	2.031ThrTyr: 2.031 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	3.166ValAla: 3.166 ± 0.038	1.102ValCys: 1.102 ± 0.023	4.137ValAsp: 4.137 ± 0.049	4.166ValGlu: 4.166 ± 0.053	2.492ValPhe: 2.492 ± 0.036	3.055ValGly: 3.055 ± 0.038	1.407ValHis: 1.407 ± 0.026	3.646ValIle: 3.646 ± 0.044	4.596ValLys: 4.596 ± 0.045	5.603ValLeu: 5.603 ± 0.054	1.077ValMet: 1.077 ± 0.02	3.087ValAsn: 3.087 ± 0.034	2.845ValPro: 2.845 ± 0.037	1.861ValGln: 1.861 ± 0.03	2.49ValArg: 2.49 ± 0.038	5.322ValSer: 5.322 ± 0.043	4.216ValThr: 4.216 ± 0.047	3.849ValVal: 3.849 ± 0.045	0.727ValTrp: 0.727 ± 0.022	2.914ValTyr: 2.914 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.374TrpAla: 0.374 ± 0.013	0.151TrpCys: 0.151 ± 0.008	0.551TrpAsp: 0.551 ± 0.017	0.789TrpGlu: 0.789 ± 0.018	0.447TrpPhe: 0.447 ± 0.014	0.335TrpGly: 0.335 ± 0.012	0.227TrpHis: 0.227 ± 0.009	0.802TrpIle: 0.802 ± 0.019	1.281TrpLys: 1.281 ± 0.03	0.798TrpLeu: 0.798 ± 0.02	0.222TrpMet: 0.222 ± 0.009	0.7TrpAsn: 0.7 ± 0.017	0.289TrpPro: 0.289 ± 0.011	0.305TrpGln: 0.305 ± 0.011	0.542TrpArg: 0.542 ± 0.016	0.828TrpSer: 0.828 ± 0.019	0.847TrpThr: 0.847 ± 0.019	0.681TrpVal: 0.681 ± 0.016	0.135TrpTrp: 0.135 ± 0.008	0.6TrpTyr: 0.6 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.869TyrAla: 1.869 ± 0.028	0.927TyrCys: 0.927 ± 0.022	2.229TyrAsp: 2.229 ± 0.033	2.201TyrGlu: 2.201 ± 0.031	1.96TyrPhe: 1.96 ± 0.03	2.322TyrGly: 2.322 ± 0.035	0.92TyrHis: 0.92 ± 0.02	2.586TyrIle: 2.586 ± 0.036	3.233TyrLys: 3.233 ± 0.043	3.343TyrLeu: 3.343 ± 0.039	0.735TyrMet: 0.735 ± 0.018	2.315TyrAsn: 2.315 ± 0.031	1.426TyrPro: 1.426 ± 0.024	1.001TyrGln: 1.001 ± 0.021	1.975TyrArg: 1.975 ± 0.033	3.361TyrSer: 3.361 ± 0.039	2.576TyrThr: 2.576 ± 0.036	2.068TyrVal: 2.068 ± 0.029	0.62TyrTrp: 0.62 ± 0.018	2.5TyrTyr: 2.5 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5313 proteins (2605626 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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