Amino acid dipepetide frequency for Chaetura pelagica (Chimney swift)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.102AlaAla: 6.102 ± 0.107	1.377AlaCys: 1.377 ± 0.039	2.935AlaAsp: 2.935 ± 0.061	4.831AlaGlu: 4.831 ± 0.088	2.657AlaPhe: 2.657 ± 0.055	4.445AlaGly: 4.445 ± 0.107	1.495AlaHis: 1.495 ± 0.045	2.952AlaIle: 2.952 ± 0.058	3.616AlaLys: 3.616 ± 0.072	6.918AlaLeu: 6.918 ± 0.108	1.523AlaMet: 1.523 ± 0.035	2.175AlaAsn: 2.175 ± 0.047	3.405AlaPro: 3.405 ± 0.092	2.991AlaGln: 2.991 ± 0.057	3.294AlaArg: 3.294 ± 0.06	5.044AlaSer: 5.044 ± 0.079	3.391AlaThr: 3.391 ± 0.06	4.887AlaVal: 4.887 ± 0.071	0.783AlaTrp: 0.783 ± 0.028	1.614AlaTyr: 1.614 ± 0.041	0.001AlaXaa: 0.001 ± 0.001
Cys	1.277CysAla: 1.277 ± 0.046	0.667CysCys: 0.667 ± 0.025	0.997CysAsp: 0.997 ± 0.034	1.267CysGlu: 1.267 ± 0.054	0.919CysPhe: 0.919 ± 0.027	1.547CysGly: 1.547 ± 0.047	0.713CysHis: 0.713 ± 0.032	0.997CysIle: 0.997 ± 0.033	1.184CysLys: 1.184 ± 0.037	2.226CysLeu: 2.226 ± 0.058	0.463CysMet: 0.463 ± 0.021	0.814CysAsn: 0.814 ± 0.03	1.607CysPro: 1.607 ± 0.078	1.088CysGln: 1.088 ± 0.038	1.299CysArg: 1.299 ± 0.04	2.082CysSer: 2.082 ± 0.06	1.221CysThr: 1.221 ± 0.043	1.626CysVal: 1.626 ± 0.071	0.317CysTrp: 0.317 ± 0.026	0.628CysTyr: 0.628 ± 0.025	0.0CysXaa: 0.0 ± 0.0
Asp	2.923AspAla: 2.923 ± 0.054	1.01AspCys: 1.01 ± 0.033	2.661AspAsp: 2.661 ± 0.061	3.531AspGlu: 3.531 ± 0.061	2.312AspPhe: 2.312 ± 0.049	3.3AspGly: 3.3 ± 0.075	1.189AspHis: 1.189 ± 0.034	2.773AspIle: 2.773 ± 0.05	2.662AspLys: 2.662 ± 0.051	5.089AspLeu: 5.089 ± 0.073	1.171AspMet: 1.171 ± 0.027	1.804AspAsn: 1.804 ± 0.047	2.939AspPro: 2.939 ± 0.06	1.805AspGln: 1.805 ± 0.041	2.271AspArg: 2.271 ± 0.051	3.882AspSer: 3.882 ± 0.071	2.544AspThr: 2.544 ± 0.045	3.289AspVal: 3.289 ± 0.06	0.628AspTrp: 0.628 ± 0.027	1.576AspTyr: 1.576 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	4.837GluAla: 4.837 ± 0.074	1.304GluCys: 1.304 ± 0.055	4.427GluAsp: 4.427 ± 0.084	8.004GluGlu: 8.004 ± 0.175	2.167GluPhe: 2.167 ± 0.045	4.129GluGly: 4.129 ± 0.093	1.558GluHis: 1.558 ± 0.04	3.347GluIle: 3.347 ± 0.055	5.519GluLys: 5.519 ± 0.122	6.606GluLeu: 6.606 ± 0.109	1.776GluMet: 1.776 ± 0.045	2.979GluAsn: 2.979 ± 0.067	2.725GluPro: 2.725 ± 0.064	3.407GluGln: 3.407 ± 0.076	3.883GluArg: 3.883 ± 0.084	4.127GluSer: 4.127 ± 0.082	3.328GluThr: 3.328 ± 0.065	4.568GluVal: 4.568 ± 0.067	0.753GluTrp: 0.753 ± 0.027	1.686GluTyr: 1.686 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	2.191PheAla: 2.191 ± 0.047	1.002PheCys: 1.002 ± 0.03	1.828PheAsp: 1.828 ± 0.044	2.042PheGlu: 2.042 ± 0.037	1.807PhePhe: 1.807 ± 0.049	2.397PheGly: 2.397 ± 0.058	1.097PheHis: 1.097 ± 0.028	2.036PheIle: 2.036 ± 0.049	1.903PheLys: 1.903 ± 0.044	4.327PheLeu: 4.327 ± 0.086	0.808PheMet: 0.808 ± 0.026	1.393PheAsn: 1.393 ± 0.036	2.081PhePro: 2.081 ± 0.046	1.884PheGln: 1.884 ± 0.043	1.951PheArg: 1.951 ± 0.044	3.449PheSer: 3.449 ± 0.051	2.189PheThr: 2.189 ± 0.057	2.25PheVal: 2.25 ± 0.048	0.504PheTrp: 0.504 ± 0.023	1.335PheTyr: 1.335 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	3.985GlyAla: 3.985 ± 0.097	1.363GlyCys: 1.363 ± 0.052	3.14GlyAsp: 3.14 ± 0.062	4.04GlyGlu: 4.04 ± 0.073	2.563GlyPhe: 2.563 ± 0.06	4.708GlyGly: 4.708 ± 0.137	1.619GlyHis: 1.619 ± 0.045	2.918GlyIle: 2.918 ± 0.068	3.963GlyLys: 3.963 ± 0.075	5.574GlyLeu: 5.574 ± 0.084	1.485GlyMet: 1.485 ± 0.039	2.537GlyAsn: 2.537 ± 0.056	2.853GlyPro: 2.853 ± 0.073	2.607GlyGln: 2.607 ± 0.048	3.521GlyArg: 3.521 ± 0.089	5.314GlySer: 5.314 ± 0.082	3.642GlyThr: 3.642 ± 0.071	3.65GlyVal: 3.65 ± 0.083	0.844GlyTrp: 0.844 ± 0.036	1.878GlyTyr: 1.878 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.302HisAla: 1.302 ± 0.036	0.717HisCys: 0.717 ± 0.028	0.912HisAsp: 0.912 ± 0.032	1.293HisGlu: 1.293 ± 0.031	1.124HisPhe: 1.124 ± 0.031	1.57HisGly: 1.57 ± 0.04	0.902HisHis: 0.902 ± 0.031	1.262HisIle: 1.262 ± 0.035	1.314HisLys: 1.314 ± 0.038	3.01HisLeu: 3.01 ± 0.064	0.585HisMet: 0.585 ± 0.026	0.946HisAsn: 0.946 ± 0.03	1.681HisPro: 1.681 ± 0.046	1.368HisGln: 1.368 ± 0.044	1.598HisArg: 1.598 ± 0.044	2.147HisSer: 2.147 ± 0.052	1.611HisThr: 1.611 ± 0.079	1.641HisVal: 1.641 ± 0.044	0.349HisTrp: 0.349 ± 0.017	0.886HisTyr: 0.886 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	2.73IleAla: 2.73 ± 0.061	1.132IleCys: 1.132 ± 0.036	2.15IleAsp: 2.15 ± 0.05	2.639IleGlu: 2.639 ± 0.046	2.001IlePhe: 2.001 ± 0.051	2.251IleGly: 2.251 ± 0.048	1.32IleHis: 1.32 ± 0.034	2.631IleIle: 2.631 ± 0.055	2.793IleLys: 2.793 ± 0.054	4.867IleLeu: 4.867 ± 0.087	1.075IleMet: 1.075 ± 0.033	1.907IleAsn: 1.907 ± 0.04	2.756IlePro: 2.756 ± 0.052	2.419IleGln: 2.419 ± 0.051	2.457IleArg: 2.457 ± 0.043	3.778IleSer: 3.778 ± 0.061	2.648IleThr: 2.648 ± 0.055	2.612IleVal: 2.612 ± 0.053	0.523IleTrp: 0.523 ± 0.019	1.651IleTyr: 1.651 ± 0.071	0.0IleXaa: 0.0 ± 0.0
Lys	4.13LysAla: 4.13 ± 0.064	1.201LysCys: 1.201 ± 0.04	3.313LysAsp: 3.313 ± 0.065	5.374LysGlu: 5.374 ± 0.133	1.856LysPhe: 1.856 ± 0.042	3.406LysGly: 3.406 ± 0.073	1.528LysHis: 1.528 ± 0.047	2.806LysIle: 2.806 ± 0.063	5.123LysLys: 5.123 ± 0.113	5.535LysLeu: 5.535 ± 0.088	1.488LysMet: 1.488 ± 0.04	2.431LysAsn: 2.431 ± 0.052	3.044LysPro: 3.044 ± 0.066	2.877LysGln: 2.877 ± 0.059	3.578LysArg: 3.578 ± 0.07	3.973LysSer: 3.973 ± 0.073	3.116LysThr: 3.116 ± 0.057	3.789LysVal: 3.789 ± 0.062	0.677LysTrp: 0.677 ± 0.029	1.78LysTyr: 1.78 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	6.756LeuAla: 6.756 ± 0.101	2.207LeuCys: 2.207 ± 0.06	4.961LeuAsp: 4.961 ± 0.077	7.222LeuGlu: 7.222 ± 0.11	3.544LeuPhe: 3.544 ± 0.061	5.886LeuGly: 5.886 ± 0.083	2.829LeuHis: 2.829 ± 0.051	4.041LeuIle: 4.041 ± 0.077	6.146LeuLys: 6.146 ± 0.098	10.755LeuLeu: 10.755 ± 0.159	2.026LeuMet: 2.026 ± 0.041	3.61LeuAsn: 3.61 ± 0.066	5.69LeuPro: 5.69 ± 0.107	5.97LeuGln: 5.97 ± 0.116	5.554LeuArg: 5.554 ± 0.078	7.988LeuSer: 7.988 ± 0.106	4.924LeuThr: 4.924 ± 0.083	5.929LeuVal: 5.929 ± 0.085	1.143LeuTrp: 1.143 ± 0.033	2.763LeuTyr: 2.763 ± 0.063	0.003LeuXaa: 0.003 ± 0.002
Met	1.756MetAla: 1.756 ± 0.037	0.487MetCys: 0.487 ± 0.021	1.308MetAsp: 1.308 ± 0.036	1.903MetGlu: 1.903 ± 0.048	0.801MetPhe: 0.801 ± 0.023	1.308MetGly: 1.308 ± 0.036	0.47MetHis: 0.47 ± 0.023	0.866MetIle: 0.866 ± 0.028	1.515MetLys: 1.515 ± 0.039	2.046MetLeu: 2.046 ± 0.038	0.555MetMet: 0.555 ± 0.027	0.913MetAsn: 0.913 ± 0.027	0.961MetPro: 0.961 ± 0.033	1.036MetGln: 1.036 ± 0.032	1.093MetArg: 1.093 ± 0.033	1.449MetSer: 1.449 ± 0.032	1.109MetThr: 1.109 ± 0.03	1.533MetVal: 1.533 ± 0.039	0.248MetTrp: 0.248 ± 0.014	0.67MetTyr: 0.67 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	2.065AsnAla: 2.065 ± 0.047	0.861AsnCys: 0.861 ± 0.03	1.495AsnAsp: 1.495 ± 0.037	2.275AsnGlu: 2.275 ± 0.06	1.542AsnPhe: 1.542 ± 0.036	2.516AsnGly: 2.516 ± 0.062	0.949AsnHis: 0.949 ± 0.032	2.245AsnIle: 2.245 ± 0.045	2.385AsnLys: 2.385 ± 0.049	3.928AsnLeu: 3.928 ± 0.055	0.898AsnMet: 0.898 ± 0.026	1.601AsnAsn: 1.601 ± 0.043	2.277AsnPro: 2.277 ± 0.052	1.608AsnGln: 1.608 ± 0.037	1.821AsnArg: 1.821 ± 0.042	3.019AsnSer: 3.019 ± 0.053	2.026AsnThr: 2.026 ± 0.045	2.308AsnVal: 2.308 ± 0.044	0.484AsnTrp: 0.484 ± 0.022	1.161AsnTyr: 1.161 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	4.201ProAla: 4.201 ± 0.087	1.173ProCys: 1.173 ± 0.046	2.697ProAsp: 2.697 ± 0.049	3.986ProGlu: 3.986 ± 0.069	1.952ProPhe: 1.952 ± 0.048	4.141ProGly: 4.141 ± 0.14	1.36ProHis: 1.36 ± 0.039	1.93ProIle: 1.93 ± 0.049	2.673ProLys: 2.673 ± 0.059	4.914ProLeu: 4.914 ± 0.082	0.961ProMet: 0.961 ± 0.033	1.84ProAsn: 1.84 ± 0.042	4.776ProPro: 4.776 ± 0.133	2.587ProGln: 2.587 ± 0.069	2.816ProArg: 2.816 ± 0.06	5.29ProSer: 5.29 ± 0.106	2.8ProThr: 2.8 ± 0.061	3.879ProVal: 3.879 ± 0.071	0.647ProTrp: 0.647 ± 0.031	1.472ProTyr: 1.472 ± 0.044	0.0ProXaa: 0.0 ± 0.0
Gln	3.307GlnAla: 3.307 ± 0.065	1.017GlnCys: 1.017 ± 0.039	2.34GlnAsp: 2.34 ± 0.052	3.937GlnGlu: 3.937 ± 0.083	1.497GlnPhe: 1.497 ± 0.04	2.848GlnGly: 2.848 ± 0.056	1.352GlnHis: 1.352 ± 0.042	2.126GlnIle: 2.126 ± 0.05	3.134GlnLys: 3.134 ± 0.069	4.944GlnLeu: 4.944 ± 0.097	1.151GlnMet: 1.151 ± 0.036	1.835GlnAsn: 1.835 ± 0.045	2.51GlnPro: 2.51 ± 0.076	3.115GlnGln: 3.115 ± 0.103	2.819GlnArg: 2.819 ± 0.061	3.104GlnSer: 3.104 ± 0.058	2.367GlnThr: 2.367 ± 0.056	2.998GlnVal: 2.998 ± 0.053	0.507GlnTrp: 0.507 ± 0.024	1.257GlnTyr: 1.257 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	3.518ArgAla: 3.518 ± 0.062	1.228ArgCys: 1.228 ± 0.039	2.705ArgAsp: 2.705 ± 0.051	3.879ArgGlu: 3.879 ± 0.074	1.958ArgPhe: 1.958 ± 0.047	3.177ArgGly: 3.177 ± 0.064	1.534ArgHis: 1.534 ± 0.037	2.465ArgIle: 2.465 ± 0.045	3.842ArgLys: 3.842 ± 0.081	4.948ArgLeu: 4.948 ± 0.077	1.166ArgMet: 1.166 ± 0.041	2.073ArgAsn: 2.073 ± 0.043	2.579ArgPro: 2.579 ± 0.052	2.583ArgGln: 2.583 ± 0.054	4.0ArgArg: 4.0 ± 0.094	4.069ArgSer: 4.069 ± 0.098	2.674ArgThr: 2.674 ± 0.048	3.352ArgVal: 3.352 ± 0.071	0.7ArgTrp: 0.7 ± 0.03	1.557ArgTyr: 1.557 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.995SerAla: 4.995 ± 0.084	2.046SerCys: 2.046 ± 0.054	3.707SerAsp: 3.707 ± 0.074	4.73SerGlu: 4.73 ± 0.095	3.11SerPhe: 3.11 ± 0.059	4.878SerGly: 4.878 ± 0.078	2.098SerHis: 2.098 ± 0.051	3.482SerIle: 3.482 ± 0.08	4.212SerLys: 4.212 ± 0.075	7.999SerLeu: 7.999 ± 0.098	1.57SerMet: 1.57 ± 0.039	2.72SerAsn: 2.72 ± 0.046	5.285SerPro: 5.285 ± 0.115	3.765SerGln: 3.765 ± 0.07	4.243SerArg: 4.243 ± 0.097	9.044SerSer: 9.044 ± 0.156	4.343SerThr: 4.343 ± 0.081	4.757SerVal: 4.757 ± 0.08	1.05SerTrp: 1.05 ± 0.041	2.191SerTyr: 2.191 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	3.753ThrAla: 3.753 ± 0.064	1.37ThrCys: 1.37 ± 0.048	2.573ThrAsp: 2.573 ± 0.055	3.444ThrGlu: 3.444 ± 0.064	2.21ThrPhe: 2.21 ± 0.053	3.442ThrGly: 3.442 ± 0.068	1.363ThrHis: 1.363 ± 0.063	2.464ThrIle: 2.464 ± 0.051	2.83ThrLys: 2.83 ± 0.061	5.305ThrLeu: 5.305 ± 0.09	1.011ThrMet: 1.011 ± 0.025	1.77ThrAsn: 1.77 ± 0.038	3.311ThrPro: 3.311 ± 0.094	2.243ThrGln: 2.243 ± 0.048	2.457ThrArg: 2.457 ± 0.052	4.426ThrSer: 4.426 ± 0.084	2.91ThrThr: 2.91 ± 0.063	3.815ThrVal: 3.815 ± 0.071	0.692ThrTrp: 0.692 ± 0.027	1.592ThrTyr: 1.592 ± 0.04	0.001ThrXaa: 0.001 ± 0.001
Val	4.333ValAla: 4.333 ± 0.089	1.8ValCys: 1.8 ± 0.096	3.027ValAsp: 3.027 ± 0.05	4.156ValGlu: 4.156 ± 0.063	2.605ValPhe: 2.605 ± 0.044	3.672ValGly: 3.672 ± 0.072	1.714ValHis: 1.714 ± 0.048	2.912ValIle: 2.912 ± 0.055	3.741ValLys: 3.741 ± 0.059	6.726ValLeu: 6.726 ± 0.086	1.35ValMet: 1.35 ± 0.034	2.332ValAsn: 2.332 ± 0.043	3.764ValPro: 3.764 ± 0.082	2.864ValGln: 2.864 ± 0.057	3.04ValArg: 3.04 ± 0.057	4.874ValSer: 4.874 ± 0.077	3.9ValThr: 3.9 ± 0.07	4.549ValVal: 4.549 ± 0.077	0.74ValTrp: 0.74 ± 0.032	1.756ValTyr: 1.756 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.747TrpAla: 0.747 ± 0.028	0.274TrpCys: 0.274 ± 0.026	0.712TrpAsp: 0.712 ± 0.026	0.815TrpGlu: 0.815 ± 0.029	0.453TrpPhe: 0.453 ± 0.018	0.732TrpGly: 0.732 ± 0.037	0.319TrpHis: 0.319 ± 0.022	0.562TrpIle: 0.562 ± 0.021	0.833TrpLys: 0.833 ± 0.028	1.243TrpLeu: 1.243 ± 0.04	0.301TrpMet: 0.301 ± 0.017	0.605TrpAsn: 0.605 ± 0.032	0.485TrpPro: 0.485 ± 0.023	0.568TrpGln: 0.568 ± 0.031	0.735TrpArg: 0.735 ± 0.034	0.856TrpSer: 0.856 ± 0.028	0.618TrpThr: 0.618 ± 0.024	0.709TrpVal: 0.709 ± 0.027	0.188TrpTrp: 0.188 ± 0.012	0.413TrpTyr: 0.413 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.527TyrAla: 1.527 ± 0.04	0.7TyrCys: 0.7 ± 0.028	1.471TyrAsp: 1.471 ± 0.038	1.764TyrGlu: 1.764 ± 0.043	1.396TyrPhe: 1.396 ± 0.042	1.847TyrGly: 1.847 ± 0.049	0.811TyrHis: 0.811 ± 0.029	1.526TyrIle: 1.526 ± 0.036	1.639TyrLys: 1.639 ± 0.041	2.982TyrLeu: 2.982 ± 0.074	0.665TyrMet: 0.665 ± 0.026	1.18TyrAsn: 1.18 ± 0.028	1.364TyrPro: 1.364 ± 0.039	1.38TyrGln: 1.38 ± 0.039	1.576TyrArg: 1.576 ± 0.042	2.307TyrSer: 2.307 ± 0.052	1.62TyrThr: 1.62 ± 0.038	1.716TyrVal: 1.716 ± 0.044	0.392TyrTrp: 0.392 ± 0.018	1.052TyrTyr: 1.052 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.001	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.001	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.018XaaXaa: 0.018 ± 0.009

Statistics based on 3162 proteins (1199214 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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