Amino acid dipepetide frequency for Ustilaginoidea virens RNA virus L

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.539AlaAla: 16.539 ± 5.416
1.272AlaCys: 1.272 ± 0.906
5.089AlaAsp: 5.089 ± 2.107
4.453AlaGlu: 4.453 ± 0.65
5.725AlaPhe: 5.725 ± 0.256
6.361AlaGly: 6.361 ± 1.201
3.181AlaHis: 3.181 ± 1.556
3.181AlaIle: 3.181 ± 1.31
2.545AlaLys: 2.545 ± 0.857
12.087AlaLeu: 12.087 ± 2.855
1.908AlaMet: 1.908 ± 0.404
6.361AlaAsn: 6.361 ± 0.709
3.817AlaPro: 3.817 ± 0.148
3.817AlaGln: 3.817 ± 0.148
9.542AlaArg: 9.542 ± 4.667
11.45AlaSer: 11.45 ± 4.264
6.361AlaThr: 6.361 ± 3.112
6.361AlaVal: 6.361 ± 3.112
0.636AlaTrp: 0.636 ± 0.502
4.453AlaTyr: 4.453 ± 0.305
0.0AlaXaa: 0.0 ± 0.0
Cys
1.272CysAla: 1.272 ± 0.049
0.0CysCys: 0.0 ± 0.0
1.908CysAsp: 1.908 ± 0.404
1.272CysGlu: 1.272 ± 0.906
0.636CysPhe: 0.636 ± 0.453
1.908CysGly: 1.908 ± 0.551
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.272CysLys: 1.272 ± 0.906
0.636CysLeu: 0.636 ± 0.453
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.272CysPro: 1.272 ± 0.906
0.0CysGln: 0.0 ± 0.0
2.545CysArg: 2.545 ± 1.812
1.272CysSer: 1.272 ± 0.906
0.0CysThr: 0.0 ± 0.0
1.272CysVal: 1.272 ± 0.906
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.089AspAla: 5.089 ± 2.107
1.272AspCys: 1.272 ± 0.906
3.817AspAsp: 3.817 ± 1.763
3.181AspGlu: 3.181 ± 0.355
3.817AspPhe: 3.817 ± 2.718
3.181AspGly: 3.181 ± 1.556
0.636AspHis: 0.636 ± 0.502
2.545AspIle: 2.545 ± 0.098
0.636AspLys: 0.636 ± 0.453
4.453AspLeu: 4.453 ± 0.305
0.636AspMet: 0.636 ± 0.453
0.636AspAsn: 0.636 ± 0.502
4.453AspPro: 4.453 ± 0.305
0.636AspGln: 0.636 ± 0.502
4.453AspArg: 4.453 ± 1.26
6.997AspSer: 6.997 ± 0.207
3.181AspThr: 3.181 ± 0.601
5.725AspVal: 5.725 ± 3.565
1.272AspTrp: 1.272 ± 0.906
1.272AspTyr: 1.272 ± 0.906
0.0AspXaa: 0.0 ± 0.0
Glu
4.453GluAla: 4.453 ± 2.216
0.0GluCys: 0.0 ± 0.0
3.181GluAsp: 3.181 ± 0.355
2.545GluGlu: 2.545 ± 0.098
2.545GluPhe: 2.545 ± 1.054
3.181GluGly: 3.181 ± 0.601
1.272GluHis: 1.272 ± 0.906
1.272GluIle: 1.272 ± 0.049
0.636GluLys: 0.636 ± 0.453
5.725GluLeu: 5.725 ± 2.166
1.272GluMet: 1.272 ± 0.049
0.0GluAsn: 0.0 ± 0.0
3.181GluPro: 3.181 ± 0.355
0.0GluGln: 0.0 ± 0.0
3.181GluArg: 3.181 ± 1.31
2.545GluSer: 2.545 ± 0.857
1.272GluThr: 1.272 ± 0.049
2.545GluVal: 2.545 ± 1.054
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.453PheAla: 4.453 ± 0.65
0.636PheCys: 0.636 ± 0.502
1.908PheAsp: 1.908 ± 0.404
1.272PheGlu: 1.272 ± 0.049
0.636PhePhe: 0.636 ± 0.502
6.361PheGly: 6.361 ± 0.709
0.0PheHis: 0.0 ± 0.0
2.545PheIle: 2.545 ± 0.098
0.0PheLys: 0.0 ± 0.0
4.453PheLeu: 4.453 ± 0.305
0.636PheMet: 0.636 ± 0.502
1.272PheAsn: 1.272 ± 0.049
2.545PhePro: 2.545 ± 0.098
1.272PheGln: 1.272 ± 0.049
1.272PheArg: 1.272 ± 0.049
1.908PheSer: 1.908 ± 0.551
0.636PheThr: 0.636 ± 0.453
3.181PheVal: 3.181 ± 1.31
1.272PheTrp: 1.272 ± 0.049
1.272PheTyr: 1.272 ± 1.004
0.0PheXaa: 0.0 ± 0.0
Gly
5.089GlyAla: 5.089 ± 2.107
1.272GlyCys: 1.272 ± 0.906
4.453GlyAsp: 4.453 ± 1.605
4.453GlyGlu: 4.453 ± 0.305
1.272GlyPhe: 1.272 ± 0.049
11.45GlyGly: 11.45 ± 2.353
5.089GlyHis: 5.089 ± 1.152
5.089GlyIle: 5.089 ± 2.107
0.636GlyLys: 0.636 ± 0.453
6.361GlyLeu: 6.361 ± 1.201
1.272GlyMet: 1.272 ± 0.906
2.545GlyAsn: 2.545 ± 0.098
3.817GlyPro: 3.817 ± 0.148
1.908GlyGln: 1.908 ± 0.404
5.725GlyArg: 5.725 ± 0.256
6.997GlySer: 6.997 ± 3.072
6.997GlyThr: 6.997 ± 1.703
5.725GlyVal: 5.725 ± 0.699
0.636GlyTrp: 0.636 ± 0.502
2.545GlyTyr: 2.545 ± 1.812
0.0GlyXaa: 0.0 ± 0.0
His
2.545HisAla: 2.545 ± 2.009
0.636HisCys: 0.636 ± 0.502
1.272HisAsp: 1.272 ± 1.004
0.636HisGlu: 0.636 ± 0.502
0.0HisPhe: 0.0 ± 0.0
0.636HisGly: 0.636 ± 0.502
1.272HisHis: 1.272 ± 0.049
2.545HisIle: 2.545 ± 0.857
1.908HisLys: 1.908 ± 0.404
2.545HisLeu: 2.545 ± 1.054
0.0HisMet: 0.0 ± 0.0
0.636HisAsn: 0.636 ± 0.502
0.0HisPro: 0.0 ± 0.0
1.272HisGln: 1.272 ± 1.004
0.636HisArg: 0.636 ± 0.453
0.636HisSer: 0.636 ± 0.453
1.908HisThr: 1.908 ± 0.404
2.545HisVal: 2.545 ± 0.857
0.636HisTrp: 0.636 ± 0.502
2.545HisTyr: 2.545 ± 0.098
0.0HisXaa: 0.0 ± 0.0
Ile
3.181IleAla: 3.181 ± 0.355
0.0IleCys: 0.0 ± 0.0
1.908IleAsp: 1.908 ± 0.404
2.545IleGlu: 2.545 ± 0.857
3.181IlePhe: 3.181 ± 1.556
3.817IleGly: 3.817 ± 0.808
0.636IleHis: 0.636 ± 0.502
1.908IleIle: 1.908 ± 0.551
1.272IleLys: 1.272 ± 0.906
5.089IleLeu: 5.089 ± 0.197
1.272IleMet: 1.272 ± 0.049
3.817IleAsn: 3.817 ± 0.808
1.908IlePro: 1.908 ± 1.507
0.636IleGln: 0.636 ± 0.502
2.545IleArg: 2.545 ± 1.812
2.545IleSer: 2.545 ± 1.812
1.272IleThr: 1.272 ± 0.049
2.545IleVal: 2.545 ± 1.812
0.636IleTrp: 0.636 ± 0.502
0.636IleTyr: 0.636 ± 0.453
0.0IleXaa: 0.0 ± 0.0
Lys
1.272LysAla: 1.272 ± 0.906
0.636LysCys: 0.636 ± 0.453
0.636LysAsp: 0.636 ± 0.453
0.636LysGlu: 0.636 ± 0.453
1.272LysPhe: 1.272 ± 0.049
0.636LysGly: 0.636 ± 0.453
0.636LysHis: 0.636 ± 0.502
0.636LysIle: 0.636 ± 0.453
1.272LysLys: 1.272 ± 0.049
4.453LysLeu: 4.453 ± 3.171
1.272LysMet: 1.272 ± 0.906
1.908LysAsn: 1.908 ± 1.359
1.908LysPro: 1.908 ± 0.404
1.272LysGln: 1.272 ± 0.906
3.181LysArg: 3.181 ± 2.265
1.272LysSer: 1.272 ± 0.049
0.636LysThr: 0.636 ± 0.453
0.636LysVal: 0.636 ± 0.502
0.0LysTrp: 0.0 ± 0.0
1.908LysTyr: 1.908 ± 0.404
0.0LysXaa: 0.0 ± 0.0
Leu
20.992LeuAla: 20.992 ± 6.065
3.817LeuCys: 3.817 ± 2.718
6.361LeuAsp: 6.361 ± 2.619
1.908LeuGlu: 1.908 ± 0.404
1.272LeuPhe: 1.272 ± 1.004
9.542LeuGly: 9.542 ± 2.019
1.272LeuHis: 1.272 ± 0.049
4.453LeuIle: 4.453 ± 3.171
1.908LeuLys: 1.908 ± 1.359
5.725LeuLeu: 5.725 ± 2.166
1.272LeuMet: 1.272 ± 0.906
3.181LeuAsn: 3.181 ± 1.31
4.453LeuPro: 4.453 ± 0.65
1.272LeuGln: 1.272 ± 0.049
8.906LeuArg: 8.906 ± 1.566
6.997LeuSer: 6.997 ± 0.207
5.089LeuThr: 5.089 ± 2.107
6.361LeuVal: 6.361 ± 0.709
1.272LeuTrp: 1.272 ± 0.049
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.908MetAla: 1.908 ± 0.551
0.0MetCys: 0.0 ± 0.0
0.636MetAsp: 0.636 ± 0.453
0.0MetGlu: 0.0 ± 0.0
1.272MetPhe: 1.272 ± 0.906
1.908MetGly: 1.908 ± 0.404
0.0MetHis: 0.0 ± 0.0
1.272MetIle: 1.272 ± 0.049
0.636MetLys: 0.636 ± 0.453
2.545MetLeu: 2.545 ± 0.857
1.272MetMet: 1.272 ± 0.71
1.272MetAsn: 1.272 ± 0.049
0.636MetPro: 0.636 ± 0.502
0.636MetGln: 0.636 ± 0.453
1.272MetArg: 1.272 ± 0.906
2.545MetSer: 2.545 ± 0.857
0.636MetThr: 0.636 ± 0.453
1.272MetVal: 1.272 ± 1.004
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.089AsnAla: 5.089 ± 3.062
1.272AsnCys: 1.272 ± 0.906
2.545AsnAsp: 2.545 ± 2.009
2.545AsnGlu: 2.545 ± 0.857
1.272AsnPhe: 1.272 ± 0.049
1.908AsnGly: 1.908 ± 0.551
0.636AsnHis: 0.636 ± 0.502
1.272AsnIle: 1.272 ± 0.906
0.636AsnLys: 0.636 ± 0.453
3.181AsnLeu: 3.181 ± 1.31
1.908AsnMet: 1.908 ± 0.404
1.908AsnAsn: 1.908 ± 0.551
1.272AsnPro: 1.272 ± 0.906
1.272AsnGln: 1.272 ± 1.004
2.545AsnArg: 2.545 ± 0.098
6.361AsnSer: 6.361 ± 1.664
3.817AsnThr: 3.817 ± 0.148
0.0AsnVal: 0.0 ± 0.0
1.272AsnTrp: 1.272 ± 0.049
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.725ProAla: 5.725 ± 0.699
0.0ProCys: 0.0 ± 0.0
3.181ProAsp: 3.181 ± 0.355
1.908ProGlu: 1.908 ± 1.359
1.908ProPhe: 1.908 ± 1.507
3.817ProGly: 3.817 ± 0.148
1.908ProHis: 1.908 ± 0.404
2.545ProIle: 2.545 ± 1.054
0.636ProLys: 0.636 ± 0.453
5.725ProLeu: 5.725 ± 0.256
0.0ProMet: 0.0 ± 0.0
1.272ProAsn: 1.272 ± 0.049
4.453ProPro: 4.453 ± 2.56
1.272ProGln: 1.272 ± 1.004
4.453ProArg: 4.453 ± 1.605
1.908ProSer: 1.908 ± 0.404
3.817ProThr: 3.817 ± 2.058
4.453ProVal: 4.453 ± 1.605
0.0ProTrp: 0.0 ± 0.0
1.272ProTyr: 1.272 ± 0.049
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.636GlnCys: 0.636 ± 0.502
0.636GlnAsp: 0.636 ± 0.453
0.636GlnGlu: 0.636 ± 0.453
0.0GlnPhe: 0.0 ± 0.0
1.908GlnGly: 1.908 ± 1.507
1.272GlnHis: 1.272 ± 0.049
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
2.545GlnLeu: 2.545 ± 2.009
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
3.817GlnPro: 3.817 ± 2.058
0.0GlnGln: 0.0 ± 0.0
3.817GlnArg: 3.817 ± 1.763
2.545GlnSer: 2.545 ± 1.054
1.272GlnThr: 1.272 ± 0.906
3.181GlnVal: 3.181 ± 0.601
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
7.634ArgAla: 7.634 ± 0.295
0.636ArgCys: 0.636 ± 0.453
4.453ArgAsp: 4.453 ± 0.65
3.817ArgGlu: 3.817 ± 0.808
1.272ArgPhe: 1.272 ± 0.049
6.997ArgGly: 6.997 ± 1.162
1.272ArgHis: 1.272 ± 1.004
4.453ArgIle: 4.453 ± 0.305
1.272ArgLys: 1.272 ± 0.906
7.634ArgLeu: 7.634 ± 0.66
1.908ArgMet: 1.908 ± 0.404
0.636ArgAsn: 0.636 ± 0.502
3.181ArgPro: 3.181 ± 0.601
1.272ArgGln: 1.272 ± 0.049
4.453ArgArg: 4.453 ± 0.65
8.27ArgSer: 8.27 ± 2.068
5.725ArgThr: 5.725 ± 0.256
9.542ArgVal: 9.542 ± 2.019
2.545ArgTrp: 2.545 ± 0.857
1.908ArgTyr: 1.908 ± 0.404
0.0ArgXaa: 0.0 ± 0.0
Ser
11.45SerAla: 11.45 ± 0.443
0.636SerCys: 0.636 ± 0.453
4.453SerAsp: 4.453 ± 0.305
1.908SerGlu: 1.908 ± 0.404
2.545SerPhe: 2.545 ± 0.857
6.361SerGly: 6.361 ± 0.246
1.272SerHis: 1.272 ± 0.906
3.181SerIle: 3.181 ± 0.355
5.089SerLys: 5.089 ± 0.758
5.725SerLeu: 5.725 ± 1.211
2.545SerMet: 2.545 ± 0.642
3.181SerAsn: 3.181 ± 1.556
3.181SerPro: 3.181 ± 0.601
2.545SerGln: 2.545 ± 0.098
3.817SerArg: 3.817 ± 1.763
8.27SerSer: 8.27 ± 0.158
3.817SerThr: 3.817 ± 0.148
6.361SerVal: 6.361 ± 0.709
3.181SerTrp: 3.181 ± 2.265
4.453SerTyr: 4.453 ± 0.305
0.0SerXaa: 0.0 ± 0.0
Thr
4.453ThrAla: 4.453 ± 3.515
0.0ThrCys: 0.0 ± 0.0
3.181ThrAsp: 3.181 ± 0.355
0.636ThrGlu: 0.636 ± 0.453
4.453ThrPhe: 4.453 ± 0.65
3.181ThrGly: 3.181 ± 0.355
1.272ThrHis: 1.272 ± 0.049
0.636ThrIle: 0.636 ± 0.502
2.545ThrLys: 2.545 ± 0.857
7.634ThrLeu: 7.634 ± 0.66
1.272ThrMet: 1.272 ± 1.004
2.545ThrAsn: 2.545 ± 0.098
0.636ThrPro: 0.636 ± 0.502
1.272ThrGln: 1.272 ± 1.004
6.361ThrArg: 6.361 ± 0.246
5.725ThrSer: 5.725 ± 0.256
5.089ThrThr: 5.089 ± 0.758
3.817ThrVal: 3.817 ± 3.013
0.0ThrTrp: 0.0 ± 0.0
1.908ThrTyr: 1.908 ± 0.551
0.0ThrXaa: 0.0 ± 0.0
Val
7.634ValAla: 7.634 ± 3.161
0.0ValCys: 0.0 ± 0.0
5.725ValAsp: 5.725 ± 0.699
3.181ValGlu: 3.181 ± 0.601
2.545ValPhe: 2.545 ± 0.098
7.634ValGly: 7.634 ± 1.25
1.908ValHis: 1.908 ± 0.404
0.636ValIle: 0.636 ± 0.453
1.272ValLys: 1.272 ± 0.906
6.997ValLeu: 6.997 ± 2.117
0.636ValMet: 0.636 ± 0.453
8.27ValAsn: 8.27 ± 1.753
3.181ValPro: 3.181 ± 1.556
1.272ValGln: 1.272 ± 0.049
6.997ValArg: 6.997 ± 2.659
5.089ValSer: 5.089 ± 1.713
2.545ValThr: 2.545 ± 1.054
1.908ValVal: 1.908 ± 0.551
0.0ValTrp: 0.0 ± 0.0
2.545ValTyr: 2.545 ± 0.857
0.0ValXaa: 0.0 ± 0.0
Trp
2.545TrpAla: 2.545 ± 0.857
0.636TrpCys: 0.636 ± 0.453
0.636TrpAsp: 0.636 ± 0.453
0.0TrpGlu: 0.0 ± 0.0
0.636TrpPhe: 0.636 ± 0.502
0.636TrpGly: 0.636 ± 0.453
0.636TrpHis: 0.636 ± 0.502
1.272TrpIle: 1.272 ± 0.049
0.636TrpLys: 0.636 ± 0.453
0.636TrpLeu: 0.636 ± 0.453
0.0TrpMet: 0.0 ± 0.0
0.636TrpAsn: 0.636 ± 0.453
0.0TrpPro: 0.0 ± 0.0
0.636TrpGln: 0.636 ± 0.502
0.636TrpArg: 0.636 ± 0.502
0.0TrpSer: 0.0 ± 0.0
1.272TrpThr: 1.272 ± 0.049
0.636TrpVal: 0.636 ± 0.453
0.0TrpTrp: 0.0 ± 0.0
1.272TrpTyr: 1.272 ± 0.049
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.817TyrAla: 3.817 ± 0.808
1.908TyrCys: 1.908 ± 0.404
1.908TyrAsp: 1.908 ± 0.404
1.272TyrGlu: 1.272 ± 0.049
1.272TyrPhe: 1.272 ± 0.906
1.908TyrGly: 1.908 ± 1.507
0.636TyrHis: 0.636 ± 0.502
1.908TyrIle: 1.908 ± 1.359
1.272TyrLys: 1.272 ± 0.906
1.908TyrLeu: 1.908 ± 0.404
0.0TyrMet: 0.0 ± 0.0
0.636TyrAsn: 0.636 ± 0.453
2.545TyrPro: 2.545 ± 1.054
0.0TyrGln: 0.0 ± 0.0
2.545TyrArg: 2.545 ± 1.812
1.272TyrSer: 1.272 ± 1.004
1.272TyrThr: 1.272 ± 0.049
1.908TyrVal: 1.908 ± 0.404
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1573 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski