Amino acid dipepetide frequency for Camelus dromedarius papillomavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.05AlaAla: 9.05 ± 2.813
2.057AlaCys: 2.057 ± 0.867
4.114AlaAsp: 4.114 ± 1.55
3.702AlaGlu: 3.702 ± 1.334
2.057AlaPhe: 2.057 ± 0.641
2.468AlaGly: 2.468 ± 0.675
0.411AlaHis: 0.411 ± 0.388
1.234AlaIle: 1.234 ± 0.635
3.291AlaLys: 3.291 ± 1.425
5.759AlaLeu: 5.759 ± 1.891
1.234AlaMet: 1.234 ± 0.615
4.114AlaAsn: 4.114 ± 1.021
6.582AlaPro: 6.582 ± 2.319
2.057AlaGln: 2.057 ± 0.774
2.879AlaArg: 2.879 ± 1.218
5.348AlaSer: 5.348 ± 2.27
7.404AlaThr: 7.404 ± 1.745
4.525AlaVal: 4.525 ± 0.98
1.645AlaTrp: 1.645 ± 0.934
4.114AlaTyr: 4.114 ± 0.957
0.0AlaXaa: 0.0 ± 0.0
Cys
1.234CysAla: 1.234 ± 0.65
0.411CysCys: 0.411 ± 0.388
0.411CysAsp: 0.411 ± 0.322
2.057CysGlu: 2.057 ± 0.894
0.823CysPhe: 0.823 ± 0.417
1.234CysGly: 1.234 ± 1.237
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.468CysLys: 2.468 ± 0.462
1.645CysLeu: 1.645 ± 0.966
0.0CysMet: 0.0 ± 0.0
0.411CysAsn: 0.411 ± 0.322
2.879CysPro: 2.879 ± 1.302
1.234CysGln: 1.234 ± 0.63
1.234CysArg: 1.234 ± 0.766
1.645CysSer: 1.645 ± 1.126
2.879CysThr: 2.879 ± 1.527
1.645CysVal: 1.645 ± 0.604
0.411CysTrp: 0.411 ± 0.322
1.645CysTyr: 1.645 ± 1.833
0.0CysXaa: 0.0 ± 0.0
Asp
4.114AspAla: 4.114 ± 0.817
1.645AspCys: 1.645 ± 0.836
2.468AspAsp: 2.468 ± 0.489
2.468AspGlu: 2.468 ± 1.062
2.879AspPhe: 2.879 ± 0.909
6.17AspGly: 6.17 ± 1.381
0.823AspHis: 0.823 ± 0.776
2.879AspIle: 2.879 ± 0.8
2.057AspLys: 2.057 ± 1.166
4.525AspLeu: 4.525 ± 1.644
0.823AspMet: 0.823 ± 0.425
1.645AspAsn: 1.645 ± 0.85
2.057AspPro: 2.057 ± 0.691
2.879AspGln: 2.879 ± 0.8
2.879AspArg: 2.879 ± 0.57
3.702AspSer: 3.702 ± 0.678
2.468AspThr: 2.468 ± 0.994
4.525AspVal: 4.525 ± 1.341
0.411AspTrp: 0.411 ± 0.322
0.823AspTyr: 0.823 ± 0.465
0.0AspXaa: 0.0 ± 0.0
Glu
4.525GluAla: 4.525 ± 1.221
1.234GluCys: 1.234 ± 0.651
3.702GluAsp: 3.702 ± 0.881
3.291GluGlu: 3.291 ± 1.158
1.645GluPhe: 1.645 ± 0.566
3.291GluGly: 3.291 ± 1.267
1.234GluHis: 1.234 ± 0.747
1.645GluIle: 1.645 ± 0.833
2.879GluLys: 2.879 ± 1.713
3.291GluLeu: 3.291 ± 1.845
0.411GluMet: 0.411 ± 0.388
3.702GluAsn: 3.702 ± 0.861
4.114GluPro: 4.114 ± 1.123
2.057GluGln: 2.057 ± 0.887
2.879GluArg: 2.879 ± 0.685
4.525GluSer: 4.525 ± 0.625
5.348GluThr: 5.348 ± 2.068
2.057GluVal: 2.057 ± 0.892
0.411GluTrp: 0.411 ± 0.388
1.645GluTyr: 1.645 ± 1.104
0.0GluXaa: 0.0 ± 0.0
Phe
2.879PheAla: 2.879 ± 0.882
0.411PheCys: 0.411 ± 0.617
1.645PheAsp: 1.645 ± 0.85
2.468PheGlu: 2.468 ± 1.344
0.823PhePhe: 0.823 ± 0.425
2.468PheGly: 2.468 ± 0.489
0.823PheHis: 0.823 ± 0.402
0.0PheIle: 0.0 ± 0.0
2.879PheLys: 2.879 ± 1.131
3.702PheLeu: 3.702 ± 0.692
0.823PheMet: 0.823 ± 0.649
0.823PheAsn: 0.823 ± 0.417
1.234PhePro: 1.234 ± 0.74
2.468PheGln: 2.468 ± 1.546
0.411PheArg: 0.411 ± 0.381
2.879PheSer: 2.879 ± 1.508
2.057PheThr: 2.057 ± 1.101
2.879PheVal: 2.879 ± 0.801
1.234PheTrp: 1.234 ± 0.65
1.645PheTyr: 1.645 ± 0.678
0.0PheXaa: 0.0 ± 0.0
Gly
3.291GlyAla: 3.291 ± 0.502
1.234GlyCys: 1.234 ± 1.143
4.525GlyAsp: 4.525 ± 1.118
5.348GlyGlu: 5.348 ± 2.631
1.234GlyPhe: 1.234 ± 0.414
6.17GlyGly: 6.17 ± 1.532
1.234GlyHis: 1.234 ± 0.756
2.468GlyIle: 2.468 ± 1.313
3.291GlyLys: 3.291 ± 1.271
4.525GlyLeu: 4.525 ± 1.657
1.645GlyMet: 1.645 ± 0.257
3.702GlyAsn: 3.702 ± 0.874
6.17GlyPro: 6.17 ± 2.473
2.468GlyGln: 2.468 ± 1.842
5.348GlyArg: 5.348 ± 2.209
7.816GlySer: 7.816 ± 1.689
5.348GlyThr: 5.348 ± 2.44
4.114GlyVal: 4.114 ± 1.324
0.823GlyTrp: 0.823 ± 0.776
1.234GlyTyr: 1.234 ± 0.635
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.823HisGlu: 0.823 ± 0.583
0.411HisPhe: 0.411 ± 0.322
2.879HisGly: 2.879 ± 0.567
0.411HisHis: 0.411 ± 0.322
0.823HisIle: 0.823 ± 0.465
0.0HisLys: 0.0 ± 0.0
3.291HisLeu: 3.291 ± 0.908
0.0HisMet: 0.0 ± 0.0
1.234HisAsn: 1.234 ± 0.706
0.823HisPro: 0.823 ± 0.762
1.234HisGln: 1.234 ± 0.826
3.291HisArg: 3.291 ± 1.162
1.645HisSer: 1.645 ± 1.287
0.823HisThr: 0.823 ± 0.62
2.879HisVal: 2.879 ± 0.712
0.411HisTrp: 0.411 ± 0.388
1.234HisTyr: 1.234 ± 0.721
0.0HisXaa: 0.0 ± 0.0
Ile
2.057IleAla: 2.057 ± 0.988
0.823IleCys: 0.823 ± 0.425
3.291IleAsp: 3.291 ± 1.029
4.114IleGlu: 4.114 ± 0.742
1.234IlePhe: 1.234 ± 0.342
4.114IleGly: 4.114 ± 1.382
0.411IleHis: 0.411 ± 0.381
1.234IleIle: 1.234 ± 0.869
1.234IleLys: 1.234 ± 0.761
0.823IleLeu: 0.823 ± 0.417
0.823IleMet: 0.823 ± 0.509
0.0IleAsn: 0.0 ± 0.0
2.057IlePro: 2.057 ± 1.037
0.411IleGln: 0.411 ± 0.322
2.879IleArg: 2.879 ± 1.482
2.057IleSer: 2.057 ± 0.641
2.879IleThr: 2.879 ± 0.52
1.234IleVal: 1.234 ± 0.451
0.411IleTrp: 0.411 ± 0.388
1.234IleTyr: 1.234 ± 0.63
0.0IleXaa: 0.0 ± 0.0
Lys
3.702LysAla: 3.702 ± 0.678
2.057LysCys: 2.057 ± 0.738
4.525LysAsp: 4.525 ± 2.03
2.468LysGlu: 2.468 ± 0.859
1.234LysPhe: 1.234 ± 0.696
4.936LysGly: 4.936 ± 1.171
2.879LysHis: 2.879 ± 0.897
1.645LysIle: 1.645 ± 0.604
2.057LysLys: 2.057 ± 0.838
4.525LysLeu: 4.525 ± 2.009
1.234LysMet: 1.234 ± 0.65
2.879LysAsn: 2.879 ± 1.314
2.468LysPro: 2.468 ± 1.027
2.879LysGln: 2.879 ± 1.289
6.993LysArg: 6.993 ± 0.732
2.468LysSer: 2.468 ± 0.522
0.823LysThr: 0.823 ± 1.027
2.057LysVal: 2.057 ± 1.607
1.234LysTrp: 1.234 ± 1.002
1.234LysTyr: 1.234 ± 0.635
0.0LysXaa: 0.0 ± 0.0
Leu
4.114LeuAla: 4.114 ± 1.141
2.057LeuCys: 2.057 ± 0.994
5.759LeuAsp: 5.759 ± 0.774
4.114LeuGlu: 4.114 ± 1.267
5.348LeuPhe: 5.348 ± 0.991
6.17LeuGly: 6.17 ± 1.516
2.468LeuHis: 2.468 ± 0.848
3.702LeuIle: 3.702 ± 1.332
5.759LeuLys: 5.759 ± 1.836
5.348LeuLeu: 5.348 ± 0.907
0.411LeuMet: 0.411 ± 0.381
4.114LeuAsn: 4.114 ± 1.222
4.936LeuPro: 4.936 ± 1.503
4.114LeuGln: 4.114 ± 1.226
2.879LeuArg: 2.879 ± 1.283
6.17LeuSer: 6.17 ± 0.706
2.879LeuThr: 2.879 ± 1.232
4.936LeuVal: 4.936 ± 1.101
1.234LeuTrp: 1.234 ± 0.65
2.879LeuTyr: 2.879 ± 0.659
0.0LeuXaa: 0.0 ± 0.0
Met
2.879MetAla: 2.879 ± 1.014
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.234MetGlu: 1.234 ± 0.767
0.823MetPhe: 0.823 ± 0.417
0.411MetGly: 0.411 ± 0.381
0.411MetHis: 0.411 ± 0.617
0.0MetIle: 0.0 ± 0.0
2.057MetLys: 2.057 ± 1.307
1.234MetLeu: 1.234 ± 0.635
0.411MetMet: 0.411 ± 0.381
0.823MetAsn: 0.823 ± 0.425
0.411MetPro: 0.411 ± 0.617
0.823MetGln: 0.823 ± 0.776
0.0MetArg: 0.0 ± 0.0
0.411MetSer: 0.411 ± 0.322
0.823MetThr: 0.823 ± 0.509
2.057MetVal: 2.057 ± 0.616
0.0MetTrp: 0.0 ± 0.0
0.411MetTyr: 0.411 ± 0.381
0.0MetXaa: 0.0 ± 0.0
Asn
2.879AsnAla: 2.879 ± 1.522
0.411AsnCys: 0.411 ± 0.388
0.0AsnAsp: 0.0 ± 0.0
1.234AsnGlu: 1.234 ± 0.685
0.823AsnPhe: 0.823 ± 0.762
1.645AsnGly: 1.645 ± 0.768
1.234AsnHis: 1.234 ± 0.823
1.234AsnIle: 1.234 ± 0.708
1.645AsnLys: 1.645 ± 0.577
3.702AsnLeu: 3.702 ± 1.201
0.0AsnMet: 0.0 ± 0.0
2.057AsnAsn: 2.057 ± 0.948
3.702AsnPro: 3.702 ± 1.401
2.879AsnGln: 2.879 ± 1.138
2.879AsnArg: 2.879 ± 0.685
2.057AsnSer: 2.057 ± 0.744
4.525AsnThr: 4.525 ± 1.473
3.702AsnVal: 3.702 ± 1.951
1.645AsnTrp: 1.645 ± 0.7
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.582ProAla: 6.582 ± 0.988
2.057ProCys: 2.057 ± 1.325
4.936ProAsp: 4.936 ± 1.745
2.879ProGlu: 2.879 ± 0.974
1.645ProPhe: 1.645 ± 0.712
4.936ProGly: 4.936 ± 1.536
0.0ProHis: 0.0 ± 0.0
3.702ProIle: 3.702 ± 0.902
2.879ProLys: 2.879 ± 0.971
7.404ProLeu: 7.404 ± 1.607
0.411ProMet: 0.411 ± 0.425
0.823ProAsn: 0.823 ± 0.762
10.695ProPro: 10.695 ± 4.154
2.879ProGln: 2.879 ± 1.17
3.702ProArg: 3.702 ± 1.822
4.936ProSer: 4.936 ± 1.845
4.936ProThr: 4.936 ± 2.114
6.17ProVal: 6.17 ± 1.552
0.0ProTrp: 0.0 ± 0.0
1.645ProTyr: 1.645 ± 1.045
0.0ProXaa: 0.0 ± 0.0
Gln
2.879GlnAla: 2.879 ± 1.294
0.411GlnCys: 0.411 ± 0.513
1.234GlnAsp: 1.234 ± 0.65
3.291GlnGlu: 3.291 ± 0.544
2.468GlnPhe: 2.468 ± 0.83
4.114GlnGly: 4.114 ± 0.809
0.0GlnHis: 0.0 ± 0.0
1.234GlnIle: 1.234 ± 0.616
1.234GlnLys: 1.234 ± 0.756
4.114GlnLeu: 4.114 ± 1.248
0.823GlnMet: 0.823 ± 0.417
2.468GlnAsn: 2.468 ± 0.912
4.525GlnPro: 4.525 ± 1.147
0.823GlnGln: 0.823 ± 0.563
0.823GlnArg: 0.823 ± 0.465
2.879GlnSer: 2.879 ± 1.113
2.468GlnThr: 2.468 ± 0.522
4.114GlnVal: 4.114 ± 1.639
0.823GlnTrp: 0.823 ± 0.643
1.645GlnTyr: 1.645 ± 0.517
0.0GlnXaa: 0.0 ± 0.0
Arg
5.759ArgAla: 5.759 ± 1.847
3.702ArgCys: 3.702 ± 1.955
2.468ArgAsp: 2.468 ± 1.038
0.0ArgGlu: 0.0 ± 0.0
1.234ArgPhe: 1.234 ± 0.451
3.291ArgGly: 3.291 ± 2.178
3.702ArgHis: 3.702 ± 0.94
1.234ArgIle: 1.234 ± 0.818
6.993ArgLys: 6.993 ± 1.309
4.936ArgLeu: 4.936 ± 1.056
0.823ArgMet: 0.823 ± 0.795
2.057ArgAsn: 2.057 ± 0.774
4.114ArgPro: 4.114 ± 1.135
2.057ArgGln: 2.057 ± 0.871
7.404ArgArg: 7.404 ± 2.509
3.291ArgSer: 3.291 ± 0.618
3.702ArgThr: 3.702 ± 0.829
3.702ArgVal: 3.702 ± 0.891
0.0ArgTrp: 0.0 ± 0.0
3.291ArgTyr: 3.291 ± 1.387
0.0ArgXaa: 0.0 ± 0.0
Ser
2.879SerAla: 2.879 ± 1.025
1.234SerCys: 1.234 ± 0.65
4.114SerAsp: 4.114 ± 1.027
5.759SerGlu: 5.759 ± 2.18
2.468SerPhe: 2.468 ± 0.522
4.936SerGly: 4.936 ± 1.824
2.468SerHis: 2.468 ± 0.907
3.291SerIle: 3.291 ± 1.12
3.291SerLys: 3.291 ± 1.105
6.582SerLeu: 6.582 ± 1.061
1.234SerMet: 1.234 ± 0.72
3.291SerAsn: 3.291 ± 0.903
3.702SerPro: 3.702 ± 0.927
3.291SerGln: 3.291 ± 1.441
7.816SerArg: 7.816 ± 1.83
6.582SerSer: 6.582 ± 1.53
5.348SerThr: 5.348 ± 2.001
4.114SerVal: 4.114 ± 0.501
1.645SerTrp: 1.645 ± 0.712
2.879SerTyr: 2.879 ± 1.167
0.0SerXaa: 0.0 ± 0.0
Thr
6.582ThrAla: 6.582 ± 3.004
1.645ThrCys: 1.645 ± 0.786
2.879ThrAsp: 2.879 ± 0.709
2.057ThrGlu: 2.057 ± 1.096
2.468ThrPhe: 2.468 ± 0.872
5.348ThrGly: 5.348 ± 1.337
0.411ThrHis: 0.411 ± 0.387
1.645ThrIle: 1.645 ± 0.257
2.879ThrLys: 2.879 ± 1.573
2.879ThrLeu: 2.879 ± 0.622
0.823ThrMet: 0.823 ± 0.425
0.411ThrAsn: 0.411 ± 0.322
5.348ThrPro: 5.348 ± 1.952
4.114ThrGln: 4.114 ± 2.306
4.114ThrArg: 4.114 ± 0.817
9.872ThrSer: 9.872 ± 2.016
6.17ThrThr: 6.17 ± 2.321
5.348ThrVal: 5.348 ± 0.712
0.823ThrTrp: 0.823 ± 0.6
2.879ThrTyr: 2.879 ± 1.189
0.0ThrXaa: 0.0 ± 0.0
Val
4.936ValAla: 4.936 ± 1.385
2.057ValCys: 2.057 ± 1.149
4.114ValAsp: 4.114 ± 1.361
3.702ValGlu: 3.702 ± 1.652
2.057ValPhe: 2.057 ± 0.641
4.114ValGly: 4.114 ± 1.663
1.234ValHis: 1.234 ± 0.553
3.291ValIle: 3.291 ± 0.971
4.936ValLys: 4.936 ± 1.303
4.525ValLeu: 4.525 ± 1.465
1.645ValMet: 1.645 ± 0.917
2.468ValAsn: 2.468 ± 0.944
4.936ValPro: 4.936 ± 0.933
1.645ValGln: 1.645 ± 0.577
2.468ValArg: 2.468 ± 1.038
5.759ValSer: 5.759 ± 2.131
4.936ValThr: 4.936 ± 1.421
4.936ValVal: 4.936 ± 2.02
0.823ValTrp: 0.823 ± 0.623
3.702ValTyr: 3.702 ± 1.137
0.0ValXaa: 0.0 ± 0.0
Trp
0.823TrpAla: 0.823 ± 0.402
0.411TrpCys: 0.411 ± 0.388
1.645TrpAsp: 1.645 ± 0.68
0.411TrpGlu: 0.411 ± 0.381
0.823TrpPhe: 0.823 ± 0.402
1.234TrpGly: 1.234 ± 0.342
0.411TrpHis: 0.411 ± 0.486
0.411TrpIle: 0.411 ± 0.322
0.823TrpLys: 0.823 ± 0.643
2.057TrpLeu: 2.057 ± 1.236
0.411TrpMet: 0.411 ± 0.486
1.234TrpAsn: 1.234 ± 0.608
0.823TrpPro: 0.823 ± 0.509
0.823TrpGln: 0.823 ± 0.465
0.0TrpArg: 0.0 ± 0.0
0.411TrpSer: 0.411 ± 0.388
0.411TrpThr: 0.411 ± 0.388
1.234TrpVal: 1.234 ± 0.614
0.411TrpTrp: 0.411 ± 0.388
0.411TrpTyr: 0.411 ± 0.388
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.879TyrAla: 2.879 ± 1.198
0.411TyrCys: 0.411 ± 0.388
0.411TyrAsp: 0.411 ± 0.381
2.468TyrGlu: 2.468 ± 0.863
2.057TyrPhe: 2.057 ± 0.903
2.057TyrGly: 2.057 ± 0.828
1.645TyrHis: 1.645 ± 0.901
1.645TyrIle: 1.645 ± 0.768
1.645TyrLys: 1.645 ± 0.68
4.525TyrLeu: 4.525 ± 0.625
0.823TyrMet: 0.823 ± 0.418
0.0TyrAsn: 0.0 ± 0.0
1.645TyrPro: 1.645 ± 1.019
1.234TyrGln: 1.234 ± 0.616
3.291TyrArg: 3.291 ± 1.452
2.468TyrSer: 2.468 ± 0.88
2.468TyrThr: 2.468 ± 0.489
2.057TyrVal: 2.057 ± 0.691
0.823TyrTrp: 0.823 ± 0.762
3.291TyrTyr: 3.291 ± 1.256
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2432 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski