Amino acid dipepetide frequency for Wuchan romanomermis nematode virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.752AlaAla: 5.752 ± 2.512
0.822AlaCys: 0.822 ± 0.745
4.93AlaAsp: 4.93 ± 1.889
1.643AlaGlu: 1.643 ± 1.135
5.752AlaPhe: 5.752 ± 1.591
10.682AlaGly: 10.682 ± 2.702
1.643AlaHis: 1.643 ± 0.671
3.287AlaIle: 3.287 ± 1.549
3.287AlaLys: 3.287 ± 1.342
6.574AlaLeu: 6.574 ± 1.934
1.643AlaMet: 1.643 ± 0.671
2.465AlaAsn: 2.465 ± 1.759
5.752AlaPro: 5.752 ± 1.789
3.287AlaGln: 3.287 ± 0.756
9.039AlaArg: 9.039 ± 0.555
4.93AlaSer: 4.93 ± 2.765
4.93AlaThr: 4.93 ± 3.004
8.217AlaVal: 8.217 ± 2.024
0.822AlaTrp: 0.822 ± 0.745
4.93AlaTyr: 4.93 ± 1.599
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.822CysAsp: 0.822 ± 0.567
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.822CysMet: 0.822 ± 0.745
0.822CysAsn: 0.822 ± 0.745
0.822CysPro: 0.822 ± 0.567
0.822CysGln: 0.822 ± 0.567
3.287CysArg: 3.287 ± 1.342
0.822CysSer: 0.822 ± 0.745
0.822CysThr: 0.822 ± 0.817
1.643CysVal: 1.643 ± 0.671
0.0CysTrp: 0.0 ± 0.0
0.822CysTyr: 0.822 ± 0.745
0.0CysXaa: 0.0 ± 0.0
Asp
7.395AspAla: 7.395 ± 2.406
0.822AspCys: 0.822 ± 0.817
4.108AspAsp: 4.108 ± 1.005
1.643AspGlu: 1.643 ± 0.671
4.108AspPhe: 4.108 ± 0.489
4.108AspGly: 4.108 ± 1.531
2.465AspHis: 2.465 ± 2.234
3.287AspIle: 3.287 ± 1.549
3.287AspLys: 3.287 ± 1.342
4.108AspLeu: 4.108 ± 1.6
0.822AspMet: 0.822 ± 0.745
0.0AspAsn: 0.0 ± 0.0
3.287AspPro: 3.287 ± 1.808
2.465AspGln: 2.465 ± 2.027
3.287AspArg: 3.287 ± 1.592
3.287AspSer: 3.287 ± 2.161
3.287AspThr: 3.287 ± 1.474
4.93AspVal: 4.93 ± 0.438
0.0AspTrp: 0.0 ± 0.0
0.822AspTyr: 0.822 ± 1.048
0.0AspXaa: 0.0 ± 0.0
Glu
0.822GluAla: 0.822 ± 0.745
0.0GluCys: 0.0 ± 0.0
0.822GluAsp: 0.822 ± 0.745
3.287GluGlu: 3.287 ± 1.592
2.465GluPhe: 2.465 ± 0.995
4.108GluGly: 4.108 ± 1.37
0.0GluHis: 0.0 ± 0.0
3.287GluIle: 3.287 ± 1.756
0.0GluLys: 0.0 ± 0.0
11.504GluLeu: 11.504 ± 1.771
0.822GluMet: 0.822 ± 0.567
1.643GluAsn: 1.643 ± 0.796
2.465GluPro: 2.465 ± 2.234
3.287GluGln: 3.287 ± 0.756
2.465GluArg: 2.465 ± 1.044
1.643GluSer: 1.643 ± 1.135
1.643GluThr: 1.643 ± 1.057
2.465GluVal: 2.465 ± 1.334
2.465GluTrp: 2.465 ± 0.623
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.108PheAla: 4.108 ± 1.138
0.822PheCys: 0.822 ± 0.745
4.108PheAsp: 4.108 ± 1.688
0.822PheGlu: 0.822 ± 1.048
0.822PhePhe: 0.822 ± 0.745
1.643PheGly: 1.643 ± 1.057
0.0PheHis: 0.0 ± 0.0
0.822PheIle: 0.822 ± 0.745
1.643PheLys: 1.643 ± 1.135
5.752PheLeu: 5.752 ± 0.538
0.822PheMet: 0.822 ± 0.745
0.822PheAsn: 0.822 ± 1.048
1.643PhePro: 1.643 ± 1.081
1.643PheGln: 1.643 ± 1.057
3.287PheArg: 3.287 ± 2.978
5.752PheSer: 5.752 ± 1.786
1.643PheThr: 1.643 ± 1.195
0.822PheVal: 0.822 ± 0.745
1.643PheTrp: 1.643 ± 1.489
1.643PheTyr: 1.643 ± 1.195
0.0PheXaa: 0.0 ± 0.0
Gly
7.395GlyAla: 7.395 ± 1.732
2.465GlyCys: 2.465 ± 0.995
4.108GlyAsp: 4.108 ± 0.489
5.752GlyGlu: 5.752 ± 2.359
4.108GlyPhe: 4.108 ± 1.59
7.395GlyGly: 7.395 ± 3.414
0.822GlyHis: 0.822 ± 0.567
2.465GlyIle: 2.465 ± 1.044
1.643GlyLys: 1.643 ± 0.922
9.039GlyLeu: 9.039 ± 1.834
0.822GlyMet: 0.822 ± 0.918
1.643GlyAsn: 1.643 ± 0.796
4.93GlyPro: 4.93 ± 2.153
2.465GlyGln: 2.465 ± 1.044
4.93GlyArg: 4.93 ± 1.99
4.93GlySer: 4.93 ± 3.405
2.465GlyThr: 2.465 ± 1.463
5.752GlyVal: 5.752 ± 0.538
2.465GlyTrp: 2.465 ± 2.234
2.465GlyTyr: 2.465 ± 1.334
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.822HisGlu: 0.822 ± 0.745
0.0HisPhe: 0.0 ± 0.0
0.822HisGly: 0.822 ± 0.567
0.822HisHis: 0.822 ± 0.567
0.822HisIle: 0.822 ± 0.567
0.822HisLys: 0.822 ± 0.745
2.465HisLeu: 2.465 ± 1.299
0.0HisMet: 0.0 ± 0.0
0.822HisAsn: 0.822 ± 0.567
0.822HisPro: 0.822 ± 0.745
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.822HisSer: 0.822 ± 0.817
0.822HisThr: 0.822 ± 0.567
2.465HisVal: 2.465 ± 1.995
0.0HisTrp: 0.0 ± 0.0
2.465HisTyr: 2.465 ± 0.995
0.0HisXaa: 0.0 ± 0.0
Ile
4.93IleAla: 4.93 ± 1.599
0.822IleCys: 0.822 ± 0.745
3.287IleAsp: 3.287 ± 0.998
1.643IleGlu: 1.643 ± 0.796
0.822IlePhe: 0.822 ± 1.048
7.395IleGly: 7.395 ± 0.633
0.0IleHis: 0.0 ± 0.0
0.822IleIle: 0.822 ± 0.745
0.822IleLys: 0.822 ± 0.745
3.287IleLeu: 3.287 ± 1.554
0.822IleMet: 0.822 ± 0.745
0.0IleAsn: 0.0 ± 0.0
4.108IlePro: 4.108 ± 1.789
2.465IleGln: 2.465 ± 1.299
3.287IleArg: 3.287 ± 1.289
4.108IleSer: 4.108 ± 0.489
1.643IleThr: 1.643 ± 1.634
2.465IleVal: 2.465 ± 1.334
0.822IleTrp: 0.822 ± 0.817
2.465IleTyr: 2.465 ± 2.027
0.0IleXaa: 0.0 ± 0.0
Lys
2.465LysAla: 2.465 ± 0.995
0.0LysCys: 0.0 ± 0.0
4.108LysAsp: 4.108 ± 1.005
2.465LysGlu: 2.465 ± 0.623
0.822LysPhe: 0.822 ± 0.567
0.822LysGly: 0.822 ± 0.817
1.643LysHis: 1.643 ± 0.671
3.287LysIle: 3.287 ± 0.998
1.643LysLys: 1.643 ± 0.671
5.752LysLeu: 5.752 ± 1.567
0.0LysMet: 0.0 ± 0.0
0.822LysAsn: 0.822 ± 0.817
2.465LysPro: 2.465 ± 1.334
0.822LysGln: 0.822 ± 0.567
1.643LysArg: 1.643 ± 0.671
3.287LysSer: 3.287 ± 1.289
3.287LysThr: 3.287 ± 1.592
0.822LysVal: 0.822 ± 0.745
1.643LysTrp: 1.643 ± 1.489
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
9.039LeuAla: 9.039 ± 2.46
2.465LeuCys: 2.465 ± 1.299
5.752LeuAsp: 5.752 ± 0.538
10.682LeuGlu: 10.682 ± 1.517
2.465LeuPhe: 2.465 ± 0.872
4.93LeuGly: 4.93 ± 2.013
0.822LeuHis: 0.822 ± 0.745
4.93LeuIle: 4.93 ± 2.095
1.643LeuLys: 1.643 ± 0.671
4.108LeuLeu: 4.108 ± 1.6
2.465LeuMet: 2.465 ± 1.51
0.0LeuAsn: 0.0 ± 0.0
4.108LeuPro: 4.108 ± 1.183
3.287LeuGln: 3.287 ± 1.843
6.574LeuArg: 6.574 ± 1.775
4.108LeuSer: 4.108 ± 1.936
4.108LeuThr: 4.108 ± 2.171
11.504LeuVal: 11.504 ± 0.977
1.643LeuTrp: 1.643 ± 0.922
6.574LeuTyr: 6.574 ± 1.996
0.0LeuXaa: 0.0 ± 0.0
Met
1.643MetAla: 1.643 ± 0.671
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.822MetPhe: 0.822 ± 0.745
1.643MetGly: 1.643 ± 1.195
0.822MetHis: 0.822 ± 0.567
0.0MetIle: 0.0 ± 0.0
0.822MetLys: 0.822 ± 0.745
2.465MetLeu: 2.465 ± 1.463
0.0MetMet: 0.0 ± 0.0
2.465MetAsn: 2.465 ± 0.995
0.0MetPro: 0.0 ± 0.0
0.822MetGln: 0.822 ± 0.567
1.643MetArg: 1.643 ± 0.671
2.465MetSer: 2.465 ± 1.463
0.0MetThr: 0.0 ± 0.0
4.108MetVal: 4.108 ± 0.489
0.822MetTrp: 0.822 ± 1.048
0.822MetTyr: 0.822 ± 0.745
0.0MetXaa: 0.0 ± 0.0
Asn
0.822AsnAla: 0.822 ± 0.745
0.822AsnCys: 0.822 ± 0.745
0.822AsnAsp: 0.822 ± 0.745
0.822AsnGlu: 0.822 ± 0.817
0.822AsnPhe: 0.822 ± 1.048
3.287AsnGly: 3.287 ± 0.756
0.0AsnHis: 0.0 ± 0.0
0.822AsnIle: 0.822 ± 0.567
0.0AsnLys: 0.0 ± 0.0
0.0AsnLeu: 0.0 ± 0.0
1.643AsnMet: 1.643 ± 0.892
2.465AsnAsn: 2.465 ± 1.575
3.287AsnPro: 3.287 ± 0.756
0.822AsnGln: 0.822 ± 1.048
0.822AsnArg: 0.822 ± 0.567
3.287AsnSer: 3.287 ± 1.554
1.643AsnThr: 1.643 ± 1.489
2.465AsnVal: 2.465 ± 1.06
0.822AsnTrp: 0.822 ± 0.745
1.643AsnTyr: 1.643 ± 0.796
0.0AsnXaa: 0.0 ± 0.0
Pro
4.93ProAla: 4.93 ± 0.905
0.0ProCys: 0.0 ± 0.0
4.93ProAsp: 4.93 ± 1.492
2.465ProGlu: 2.465 ± 1.334
2.465ProPhe: 2.465 ± 1.995
5.752ProGly: 5.752 ± 1.389
0.822ProHis: 0.822 ± 0.745
2.465ProIle: 2.465 ± 1.299
0.822ProLys: 0.822 ± 0.567
2.465ProLeu: 2.465 ± 0.995
2.465ProMet: 2.465 ± 0.917
1.643ProAsn: 1.643 ± 1.195
0.822ProPro: 0.822 ± 0.567
4.108ProGln: 4.108 ± 1.532
3.287ProArg: 3.287 ± 0.6
4.93ProSer: 4.93 ± 2.259
2.465ProThr: 2.465 ± 0.623
3.287ProVal: 3.287 ± 0.756
1.643ProTrp: 1.643 ± 0.671
0.822ProTyr: 0.822 ± 1.048
0.0ProXaa: 0.0 ± 0.0
Gln
5.752GlnAla: 5.752 ± 1.754
0.822GlnCys: 0.822 ± 0.567
0.822GlnAsp: 0.822 ± 0.567
1.643GlnGlu: 1.643 ± 1.135
2.465GlnPhe: 2.465 ± 1.531
4.93GlnGly: 4.93 ± 0.873
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
2.465GlnLys: 2.465 ± 1.51
3.287GlnLeu: 3.287 ± 1.554
1.643GlnMet: 1.643 ± 0.796
1.643GlnAsn: 1.643 ± 0.922
4.93GlnPro: 4.93 ± 1.715
4.93GlnGln: 4.93 ± 1.599
1.643GlnArg: 1.643 ± 1.057
2.465GlnSer: 2.465 ± 1.299
0.822GlnThr: 0.822 ± 0.745
4.108GlnVal: 4.108 ± 1.149
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.108ArgAla: 4.108 ± 0.859
0.0ArgCys: 0.0 ± 0.0
3.287ArgAsp: 3.287 ± 0.998
1.643ArgGlu: 1.643 ± 1.489
2.465ArgPhe: 2.465 ± 1.06
4.108ArgGly: 4.108 ± 1.852
2.465ArgHis: 2.465 ± 2.027
6.574ArgIle: 6.574 ± 1.486
3.287ArgLys: 3.287 ± 2.27
9.86ArgLeu: 9.86 ± 2.576
1.643ArgMet: 1.643 ± 1.489
0.0ArgAsn: 0.0 ± 0.0
4.108ArgPro: 4.108 ± 1.149
4.93ArgGln: 4.93 ± 1.4
17.256ArgArg: 17.256 ± 11.153
4.108ArgSer: 4.108 ± 1.005
3.287ArgThr: 3.287 ± 1.119
3.287ArgVal: 3.287 ± 0.998
1.643ArgTrp: 1.643 ± 1.081
1.643ArgTyr: 1.643 ± 1.634
0.0ArgXaa: 0.0 ± 0.0
Ser
12.325SerAla: 12.325 ± 2.528
0.822SerCys: 0.822 ± 0.567
1.643SerAsp: 1.643 ± 1.135
3.287SerGlu: 3.287 ± 1.935
2.465SerPhe: 2.465 ± 1.06
7.395SerGly: 7.395 ± 1.957
0.0SerHis: 0.0 ± 0.0
2.465SerIle: 2.465 ± 0.995
3.287SerLys: 3.287 ± 1.289
9.86SerLeu: 9.86 ± 0.653
0.822SerMet: 0.822 ± 1.048
3.287SerAsn: 3.287 ± 2.008
2.465SerPro: 2.465 ± 1.463
0.822SerGln: 0.822 ± 0.567
3.287SerArg: 3.287 ± 0.756
9.039SerSer: 9.039 ± 4.542
4.108SerThr: 4.108 ± 1.005
7.395SerVal: 7.395 ± 2.676
3.287SerTrp: 3.287 ± 0.6
0.822SerTyr: 0.822 ± 1.048
0.0SerXaa: 0.0 ± 0.0
Thr
6.574ThrAla: 6.574 ± 3.635
0.0ThrCys: 0.0 ± 0.0
1.643ThrAsp: 1.643 ± 0.671
1.643ThrGlu: 1.643 ± 0.671
1.643ThrPhe: 1.643 ± 1.634
1.643ThrGly: 1.643 ± 0.796
0.822ThrHis: 0.822 ± 0.567
3.287ThrIle: 3.287 ± 2.13
1.643ThrLys: 1.643 ± 1.195
3.287ThrLeu: 3.287 ± 0.998
0.822ThrMet: 0.822 ± 0.745
1.643ThrAsn: 1.643 ± 1.489
2.465ThrPro: 2.465 ± 0.623
1.643ThrGln: 1.643 ± 0.796
3.287ThrArg: 3.287 ± 0.6
5.752ThrSer: 5.752 ± 2.044
0.822ThrThr: 0.822 ± 0.817
2.465ThrVal: 2.465 ± 2.095
1.643ThrTrp: 1.643 ± 1.057
0.822ThrTyr: 0.822 ± 0.745
0.0ThrXaa: 0.0 ± 0.0
Val
7.395ValAla: 7.395 ± 1.648
0.822ValCys: 0.822 ± 0.567
6.574ValAsp: 6.574 ± 4.228
1.643ValGlu: 1.643 ± 1.135
4.108ValPhe: 4.108 ± 1.836
7.395ValGly: 7.395 ± 0.724
0.822ValHis: 0.822 ± 0.817
1.643ValIle: 1.643 ± 0.922
5.752ValLys: 5.752 ± 1.567
3.287ValLeu: 3.287 ± 1.549
0.0ValMet: 0.0 ± 0.0
2.465ValAsn: 2.465 ± 1.06
3.287ValPro: 3.287 ± 0.6
4.108ValGln: 4.108 ± 1.005
8.217ValArg: 8.217 ± 3.354
8.217ValSer: 8.217 ± 2.108
4.108ValThr: 4.108 ± 2.339
5.752ValVal: 5.752 ± 2.484
0.822ValTrp: 0.822 ± 0.817
3.287ValTyr: 3.287 ± 2.008
0.0ValXaa: 0.0 ± 0.0
Trp
0.822TrpAla: 0.822 ± 0.745
0.0TrpCys: 0.0 ± 0.0
2.465TrpAsp: 2.465 ± 1.06
1.643TrpGlu: 1.643 ± 1.081
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
2.465TrpIle: 2.465 ± 1.463
4.108TrpLys: 4.108 ± 1.138
2.465TrpLeu: 2.465 ± 1.531
1.643TrpMet: 1.643 ± 0.668
0.822TrpAsn: 0.822 ± 0.745
0.822TrpPro: 0.822 ± 1.048
0.0TrpGln: 0.0 ± 0.0
1.643TrpArg: 1.643 ± 0.922
0.822TrpSer: 0.822 ± 0.567
0.822TrpThr: 0.822 ± 0.745
2.465TrpVal: 2.465 ± 0.872
1.643TrpTrp: 1.643 ± 1.057
0.822TrpTyr: 0.822 ± 0.745
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.108TyrAla: 4.108 ± 0.859
0.0TyrCys: 0.0 ± 0.0
3.287TyrAsp: 3.287 ± 2.13
1.643TyrGlu: 1.643 ± 1.135
1.643TyrPhe: 1.643 ± 1.489
0.822TyrGly: 0.822 ± 0.745
0.822TyrHis: 0.822 ± 0.567
3.287TyrIle: 3.287 ± 1.808
0.822TyrLys: 0.822 ± 0.567
1.643TyrLeu: 1.643 ± 1.135
0.822TyrMet: 0.822 ± 0.567
1.643TyrAsn: 1.643 ± 0.671
0.0TyrPro: 0.0 ± 0.0
1.643TyrGln: 1.643 ± 1.489
0.822TyrArg: 0.822 ± 0.745
4.108TyrSer: 4.108 ± 2.932
0.822TyrThr: 0.822 ± 1.048
3.287TyrVal: 3.287 ± 1.592
1.643TyrTrp: 1.643 ± 2.097
1.643TyrTyr: 1.643 ± 0.671
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1218 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski