Amino acid dipepetide frequency for Cacao swollen shoot Ghana J virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.764AlaAla: 3.764 ± 2.073
0.418AlaCys: 0.418 ± 1.274
0.836AlaAsp: 0.836 ± 0.434
5.437AlaGlu: 5.437 ± 3.515
3.346AlaPhe: 3.346 ± 1.738
1.673AlaGly: 1.673 ± 1.549
1.255AlaHis: 1.255 ± 0.983
4.182AlaIle: 4.182 ± 2.775
4.601AlaLys: 4.601 ± 2.934
5.019AlaLeu: 5.019 ± 1.733
3.346AlaMet: 3.346 ± 2.586
1.673AlaAsn: 1.673 ± 0.918
0.836AlaPro: 0.836 ± 0.434
2.509AlaGln: 2.509 ± 1.303
3.346AlaArg: 3.346 ± 1.05
4.182AlaSer: 4.182 ± 3.805
4.182AlaThr: 4.182 ± 2.455
3.346AlaVal: 3.346 ± 1.888
0.418AlaTrp: 0.418 ± 0.217
2.928AlaTyr: 2.928 ± 1.905
0.0AlaXaa: 0.0 ± 0.0
Cys
0.836CysAla: 0.836 ± 0.434
0.418CysCys: 0.418 ± 0.217
0.0CysAsp: 0.0 ± 0.0
0.418CysGlu: 0.418 ± 1.274
0.418CysPhe: 0.418 ± 0.217
0.418CysGly: 0.418 ± 0.217
0.836CysHis: 0.836 ± 0.434
0.418CysIle: 0.418 ± 0.217
2.509CysLys: 2.509 ± 1.303
0.836CysLeu: 0.836 ± 0.434
0.836CysMet: 0.836 ± 0.816
2.509CysAsn: 2.509 ± 1.303
0.836CysPro: 0.836 ± 0.434
1.673CysGln: 1.673 ± 0.869
0.0CysArg: 0.0 ± 0.0
0.418CysSer: 0.418 ± 0.217
0.836CysThr: 0.836 ± 0.434
0.418CysVal: 0.418 ± 0.217
0.0CysTrp: 0.0 ± 0.0
0.836CysTyr: 0.836 ± 0.434
0.0CysXaa: 0.0 ± 0.0
Asp
3.764AspAla: 3.764 ± 1.707
0.836AspCys: 0.836 ± 0.434
2.928AspAsp: 2.928 ± 1.521
4.182AspGlu: 4.182 ± 1.513
2.091AspPhe: 2.091 ± 0.872
2.509AspGly: 2.509 ± 2.546
0.836AspHis: 0.836 ± 0.434
1.255AspIle: 1.255 ± 0.652
3.346AspLys: 3.346 ± 1.738
4.601AspLeu: 4.601 ± 1.993
0.418AspMet: 0.418 ± 0.217
3.346AspAsn: 3.346 ± 1.05
2.509AspPro: 2.509 ± 1.787
1.255AspGln: 1.255 ± 0.652
2.091AspArg: 2.091 ± 1.453
3.346AspSer: 3.346 ± 0.984
4.182AspThr: 4.182 ± 1.075
2.509AspVal: 2.509 ± 0.883
0.836AspTrp: 0.836 ± 0.434
2.509AspTyr: 2.509 ± 1.303
0.0AspXaa: 0.0 ± 0.0
Glu
3.346GluAla: 3.346 ± 1.043
0.836GluCys: 0.836 ± 0.434
5.019GluAsp: 5.019 ± 1.867
15.893GluGlu: 15.893 ± 3.37
1.673GluPhe: 1.673 ± 0.869
5.437GluGly: 5.437 ± 2.084
2.091GluHis: 2.091 ± 0.901
5.855GluIle: 5.855 ± 0.585
4.601GluLys: 4.601 ± 3.383
4.601GluLeu: 4.601 ± 1.823
1.255GluMet: 1.255 ± 0.652
3.346GluAsn: 3.346 ± 1.043
0.418GluPro: 0.418 ± 0.217
5.437GluGln: 5.437 ± 1.652
3.764GluArg: 3.764 ± 1.006
6.692GluSer: 6.692 ± 2.027
2.509GluThr: 2.509 ± 0.935
4.182GluVal: 4.182 ± 1.44
0.836GluTrp: 0.836 ± 1.089
3.346GluTyr: 3.346 ± 1.134
0.0GluXaa: 0.0 ± 0.0
Phe
2.091PheAla: 2.091 ± 1.086
1.255PheCys: 1.255 ± 0.652
2.091PheAsp: 2.091 ± 1.29
1.673PheGlu: 1.673 ± 0.869
0.418PhePhe: 0.418 ± 0.217
0.418PheGly: 0.418 ± 0.217
1.673PheHis: 1.673 ± 0.869
2.928PheIle: 2.928 ± 1.521
1.673PheLys: 1.673 ± 0.869
2.928PheLeu: 2.928 ± 1.512
0.418PheMet: 0.418 ± 0.217
1.673PheAsn: 1.673 ± 0.869
1.673PhePro: 1.673 ± 0.869
1.673PheGln: 1.673 ± 0.914
2.928PheArg: 2.928 ± 1.041
4.182PheSer: 4.182 ± 1.343
0.418PheThr: 0.418 ± 0.217
0.418PheVal: 0.418 ± 0.217
0.418PheTrp: 0.418 ± 0.217
1.673PheTyr: 1.673 ± 0.869
0.0PheXaa: 0.0 ± 0.0
Gly
2.091GlyAla: 2.091 ± 0.872
0.836GlyCys: 0.836 ± 0.434
2.509GlyAsp: 2.509 ± 0.883
2.928GlyGlu: 2.928 ± 1.521
1.673GlyPhe: 1.673 ± 0.853
1.673GlyGly: 1.673 ± 0.869
0.418GlyHis: 0.418 ± 0.217
3.764GlyIle: 3.764 ± 2.404
3.346GlyLys: 3.346 ± 0.984
4.601GlyLeu: 4.601 ± 0.956
0.418GlyMet: 0.418 ± 0.217
2.509GlyAsn: 2.509 ± 1.294
0.0GlyPro: 0.0 ± 0.0
2.091GlyGln: 2.091 ± 1.256
5.855GlyArg: 5.855 ± 1.394
2.509GlySer: 2.509 ± 0.933
5.437GlyThr: 5.437 ± 1.623
2.928GlyVal: 2.928 ± 1.697
1.255GlyTrp: 1.255 ± 0.652
1.673GlyTyr: 1.673 ± 0.869
0.0GlyXaa: 0.0 ± 0.0
His
1.255HisAla: 1.255 ± 0.773
1.255HisCys: 1.255 ± 0.652
0.836HisAsp: 0.836 ± 1.125
2.091HisGlu: 2.091 ± 0.901
1.255HisPhe: 1.255 ± 0.773
1.673HisGly: 1.673 ± 0.914
1.255HisHis: 1.255 ± 1.692
1.673HisIle: 1.673 ± 0.869
1.255HisLys: 1.255 ± 1.002
3.346HisLeu: 3.346 ± 1.835
0.418HisMet: 0.418 ± 0.217
1.255HisAsn: 1.255 ± 0.983
0.418HisPro: 0.418 ± 0.217
2.091HisGln: 2.091 ± 1.086
1.673HisArg: 1.673 ± 0.869
2.928HisSer: 2.928 ± 0.946
1.673HisThr: 1.673 ± 0.918
1.255HisVal: 1.255 ± 0.652
0.836HisTrp: 0.836 ± 0.434
0.418HisTyr: 0.418 ± 0.217
0.0HisXaa: 0.0 ± 0.0
Ile
3.346IleAla: 3.346 ± 1.033
0.836IleCys: 0.836 ± 0.434
2.928IleAsp: 2.928 ± 1.521
5.855IleGlu: 5.855 ± 1.701
2.091IlePhe: 2.091 ± 0.901
3.346IleGly: 3.346 ± 1.134
2.091IleHis: 2.091 ± 0.798
3.346IleIle: 3.346 ± 1.043
3.764IleLys: 3.764 ± 1.278
8.365IleLeu: 8.365 ± 3.469
0.836IleMet: 0.836 ± 0.849
2.928IleAsn: 2.928 ± 1.026
5.855IlePro: 5.855 ± 4.301
5.437IleGln: 5.437 ± 2.86
2.928IleArg: 2.928 ± 1.521
2.509IleSer: 2.509 ± 1.303
5.855IleThr: 5.855 ± 1.499
3.346IleVal: 3.346 ± 1.35
0.418IleTrp: 0.418 ± 0.217
1.673IleTyr: 1.673 ± 0.869
0.0IleXaa: 0.0 ± 0.0
Lys
4.182LysAla: 4.182 ± 2.24
0.418LysCys: 0.418 ± 0.217
4.182LysAsp: 4.182 ± 0.983
4.182LysGlu: 4.182 ± 2.172
2.509LysPhe: 2.509 ± 0.893
2.509LysGly: 2.509 ± 0.933
4.182LysHis: 4.182 ± 1.44
4.182LysIle: 4.182 ± 2.207
5.437LysLys: 5.437 ± 4.278
7.11LysLeu: 7.11 ± 4.458
1.673LysMet: 1.673 ± 0.755
3.346LysAsn: 3.346 ± 1.827
2.928LysPro: 2.928 ± 1.016
5.019LysGln: 5.019 ± 2.564
4.182LysArg: 4.182 ± 1.275
5.019LysSer: 5.019 ± 1.871
2.928LysThr: 2.928 ± 1.009
2.928LysVal: 2.928 ± 1.89
0.836LysTrp: 0.836 ± 1.089
1.673LysTyr: 1.673 ± 0.755
0.0LysXaa: 0.0 ± 0.0
Leu
7.528LeuAla: 7.528 ± 5.504
1.673LeuCys: 1.673 ± 0.755
3.764LeuAsp: 3.764 ± 1.429
8.365LeuGlu: 8.365 ± 2.423
2.928LeuPhe: 2.928 ± 1.521
5.855LeuGly: 5.855 ± 2.702
3.346LeuHis: 3.346 ± 4.241
6.274LeuIle: 6.274 ± 3.071
6.692LeuLys: 6.692 ± 2.835
7.11LeuLeu: 7.11 ± 2.285
0.836LeuMet: 0.836 ± 0.434
3.346LeuAsn: 3.346 ± 1.043
4.601LeuPro: 4.601 ± 1.515
5.019LeuGln: 5.019 ± 1.115
3.764LeuArg: 3.764 ± 1.278
7.528LeuSer: 7.528 ± 2.098
5.437LeuThr: 5.437 ± 1.588
6.692LeuVal: 6.692 ± 2.267
0.836LeuTrp: 0.836 ± 0.434
3.346LeuTyr: 3.346 ± 2.212
0.0LeuXaa: 0.0 ± 0.0
Met
1.673MetAla: 1.673 ± 0.755
0.0MetCys: 0.0 ± 0.0
0.836MetAsp: 0.836 ± 0.434
3.346MetGlu: 3.346 ± 1.05
1.255MetPhe: 1.255 ± 0.652
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.673MetIle: 1.673 ± 1.697
3.346MetLys: 3.346 ± 2.377
2.091MetLeu: 2.091 ± 0.798
2.509MetMet: 2.509 ± 3.614
0.836MetAsn: 0.836 ± 0.434
2.091MetPro: 2.091 ± 1.086
1.255MetGln: 1.255 ± 0.773
0.836MetArg: 0.836 ± 0.849
1.673MetSer: 1.673 ± 2.4
2.509MetThr: 2.509 ± 1.079
0.418MetVal: 0.418 ± 0.968
0.418MetTrp: 0.418 ± 0.217
0.418MetTyr: 0.418 ± 0.217
0.0MetXaa: 0.0 ± 0.0
Asn
0.836AsnAla: 0.836 ± 0.434
0.0AsnCys: 0.0 ± 0.0
3.346AsnAsp: 3.346 ± 1.738
2.509AsnGlu: 2.509 ± 1.303
1.255AsnPhe: 1.255 ± 0.652
3.346AsnGly: 3.346 ± 1.033
1.255AsnHis: 1.255 ± 0.652
2.091AsnIle: 2.091 ± 1.086
3.346AsnLys: 3.346 ± 2.132
6.692AsnLeu: 6.692 ± 2.835
1.673AsnMet: 1.673 ± 0.755
2.091AsnAsn: 2.091 ± 1.256
1.255AsnPro: 1.255 ± 0.652
2.928AsnGln: 2.928 ± 2.968
2.091AsnArg: 2.091 ± 1.29
1.255AsnSer: 1.255 ± 0.652
2.509AsnThr: 2.509 ± 1.303
1.673AsnVal: 1.673 ± 0.853
0.836AsnTrp: 0.836 ± 1.125
1.673AsnTyr: 1.673 ± 0.869
0.0AsnXaa: 0.0 ± 0.0
Pro
2.509ProAla: 2.509 ± 1.243
0.418ProCys: 0.418 ± 0.217
3.346ProAsp: 3.346 ± 1.05
2.509ProGlu: 2.509 ± 0.933
1.255ProPhe: 1.255 ± 1.002
1.673ProGly: 1.673 ± 0.914
0.836ProHis: 0.836 ± 0.434
2.091ProIle: 2.091 ± 0.868
2.091ProLys: 2.091 ± 1.256
3.764ProLeu: 3.764 ± 1.026
2.091ProMet: 2.091 ± 0.769
1.673ProAsn: 1.673 ± 0.869
4.182ProPro: 4.182 ± 1.513
2.928ProGln: 2.928 ± 1.521
1.673ProArg: 1.673 ± 0.869
3.764ProSer: 3.764 ± 1.955
2.509ProThr: 2.509 ± 1.546
1.255ProVal: 1.255 ± 0.652
0.418ProTrp: 0.418 ± 0.217
1.255ProTyr: 1.255 ± 0.894
0.0ProXaa: 0.0 ± 0.0
Gln
4.601GlnAla: 4.601 ± 2.217
0.418GlnCys: 0.418 ± 0.217
2.928GlnAsp: 2.928 ± 1.122
7.11GlnGlu: 7.11 ± 2.545
1.255GlnPhe: 1.255 ± 0.652
2.509GlnGly: 2.509 ± 1.243
1.673GlnHis: 1.673 ± 0.869
3.764GlnIle: 3.764 ± 1.339
5.019GlnLys: 5.019 ± 2.662
7.11GlnLeu: 7.11 ± 3.458
2.091GlnMet: 2.091 ± 1.063
2.091GlnAsn: 2.091 ± 0.868
4.182GlnPro: 4.182 ± 0.937
6.274GlnGln: 6.274 ± 1.415
2.509GlnArg: 2.509 ± 1.243
2.091GlnSer: 2.091 ± 1.387
1.673GlnThr: 1.673 ± 0.914
4.182GlnVal: 4.182 ± 0.937
1.255GlnTrp: 1.255 ± 0.652
0.836GlnTyr: 0.836 ± 0.434
0.0GlnXaa: 0.0 ± 0.0
Arg
3.764ArgAla: 3.764 ± 2.073
0.836ArgCys: 0.836 ± 0.434
2.928ArgAsp: 2.928 ± 1.122
2.091ArgGlu: 2.091 ± 2.114
1.255ArgPhe: 1.255 ± 0.652
2.091ArgGly: 2.091 ± 0.868
0.0ArgHis: 0.0 ± 0.0
4.601ArgIle: 4.601 ± 1.697
2.509ArgLys: 2.509 ± 2.546
5.437ArgLeu: 5.437 ± 1.888
2.928ArgMet: 2.928 ± 1.026
2.091ArgAsn: 2.091 ± 1.086
1.255ArgPro: 1.255 ± 0.652
3.764ArgGln: 3.764 ± 2.095
5.437ArgArg: 5.437 ± 1.616
5.019ArgSer: 5.019 ± 1.935
2.091ArgThr: 2.091 ± 0.868
5.019ArgVal: 5.019 ± 2.815
1.255ArgTrp: 1.255 ± 0.652
0.836ArgTyr: 0.836 ± 0.434
0.0ArgXaa: 0.0 ± 0.0
Ser
2.091SerAla: 2.091 ± 2.75
1.255SerCys: 1.255 ± 0.652
3.764SerAsp: 3.764 ± 1.339
2.091SerGlu: 2.091 ± 0.872
2.091SerPhe: 2.091 ± 0.798
2.928SerGly: 2.928 ± 1.041
2.509SerHis: 2.509 ± 0.935
4.601SerIle: 4.601 ± 2.334
6.692SerLys: 6.692 ± 1.252
8.365SerLeu: 8.365 ± 1.939
1.255SerMet: 1.255 ± 0.652
2.928SerAsn: 2.928 ± 1.016
2.091SerPro: 2.091 ± 0.868
4.182SerGln: 4.182 ± 2.134
3.764SerArg: 3.764 ± 1.359
5.855SerSer: 5.855 ± 5.568
5.437SerThr: 5.437 ± 2.824
2.091SerVal: 2.091 ± 0.901
0.418SerTrp: 0.418 ± 0.217
3.346SerTyr: 3.346 ± 1.033
0.0SerXaa: 0.0 ± 0.0
Thr
3.764ThrAla: 3.764 ± 2.366
1.255ThrCys: 1.255 ± 0.652
1.673ThrAsp: 1.673 ± 0.853
4.601ThrGlu: 4.601 ± 1.615
1.673ThrPhe: 1.673 ± 0.869
4.601ThrGly: 4.601 ± 1.175
2.509ThrHis: 2.509 ± 0.883
7.11ThrIle: 7.11 ± 2.476
3.346ThrLys: 3.346 ± 1.738
4.182ThrLeu: 4.182 ± 0.983
1.673ThrMet: 1.673 ± 0.755
1.673ThrAsn: 1.673 ± 1.697
2.509ThrPro: 2.509 ± 1.303
2.509ThrGln: 2.509 ± 2.527
3.764ThrArg: 3.764 ± 2.073
5.019ThrSer: 5.019 ± 2.607
6.274ThrThr: 6.274 ± 3.434
2.928ThrVal: 2.928 ± 1.082
0.418ThrTrp: 0.418 ± 0.217
0.418ThrTyr: 0.418 ± 0.217
0.0ThrXaa: 0.0 ± 0.0
Val
2.091ValAla: 2.091 ± 1.086
1.255ValCys: 1.255 ± 0.652
3.346ValAsp: 3.346 ± 0.984
2.091ValGlu: 2.091 ± 3.395
4.182ValPhe: 4.182 ± 2.172
2.509ValGly: 2.509 ± 0.933
1.255ValHis: 1.255 ± 0.652
4.601ValIle: 4.601 ± 4.435
3.346ValLys: 3.346 ± 0.922
3.346ValLeu: 3.346 ± 1.134
2.091ValMet: 2.091 ± 2.652
1.673ValAsn: 1.673 ± 1.417
2.509ValPro: 2.509 ± 1.303
4.601ValGln: 4.601 ± 0.932
2.509ValArg: 2.509 ± 1.243
1.673ValSer: 1.673 ± 2.179
2.509ValThr: 2.509 ± 1.303
2.509ValVal: 2.509 ± 0.883
0.418ValTrp: 0.418 ± 0.217
1.255ValTyr: 1.255 ± 0.652
0.0ValXaa: 0.0 ± 0.0
Trp
0.836TrpAla: 0.836 ± 1.125
0.0TrpCys: 0.0 ± 0.0
0.418TrpAsp: 0.418 ± 0.217
1.673TrpGlu: 1.673 ± 0.918
0.0TrpPhe: 0.0 ± 0.0
0.836TrpGly: 0.836 ± 0.434
0.418TrpHis: 0.418 ± 0.217
1.255TrpIle: 1.255 ± 0.652
0.418TrpLys: 0.418 ± 0.217
2.091TrpLeu: 2.091 ± 1.086
0.0TrpMet: 0.0 ± 0.0
0.418TrpAsn: 0.418 ± 0.217
0.0TrpPro: 0.0 ± 0.0
0.836TrpGln: 0.836 ± 0.434
0.418TrpArg: 0.418 ± 0.217
0.0TrpSer: 0.0 ± 0.0
1.673TrpThr: 1.673 ± 0.869
0.836TrpVal: 0.836 ± 0.434
0.0TrpTrp: 0.0 ± 0.0
0.418TrpTyr: 0.418 ± 1.225
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.928TyrAla: 2.928 ± 1.521
1.255TyrCys: 1.255 ± 0.652
1.673TyrAsp: 1.673 ± 0.914
2.091TyrGlu: 2.091 ± 0.901
0.0TyrPhe: 0.0 ± 0.0
2.509TyrGly: 2.509 ± 1.079
0.418TyrHis: 0.418 ± 0.217
2.091TyrIle: 2.091 ± 1.086
2.091TyrLys: 2.091 ± 0.872
3.346TyrLeu: 3.346 ± 1.043
0.0TyrMet: 0.0 ± 0.0
1.255TyrAsn: 1.255 ± 0.652
2.091TyrPro: 2.091 ± 0.872
2.509TyrGln: 2.509 ± 0.933
1.673TyrArg: 1.673 ± 0.853
2.091TyrSer: 2.091 ± 0.872
1.255TyrThr: 1.255 ± 0.652
0.836TyrVal: 0.836 ± 0.434
0.418TyrTrp: 0.418 ± 0.217
1.255TyrTyr: 1.255 ± 0.652
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2392 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski