Amino acid dipepetide frequency for Hubei odonate virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.876AlaAla: 2.876 ± 0.989
1.046AlaCys: 1.046 ± 0.677
3.399AlaAsp: 3.399 ± 0.728
5.229AlaGlu: 5.229 ± 1.731
3.399AlaPhe: 3.399 ± 0.887
1.83AlaGly: 1.83 ± 0.856
0.0AlaHis: 0.0 ± 0.0
5.752AlaIle: 5.752 ± 0.562
3.137AlaLys: 3.137 ± 1.078
6.013AlaLeu: 6.013 ± 1.214
0.784AlaMet: 0.784 ± 0.446
3.137AlaAsn: 3.137 ± 1.244
3.137AlaPro: 3.137 ± 1.511
2.614AlaGln: 2.614 ± 0.597
3.66AlaArg: 3.66 ± 0.677
4.444AlaSer: 4.444 ± 1.019
2.092AlaThr: 2.092 ± 0.37
3.66AlaVal: 3.66 ± 0.916
0.261AlaTrp: 0.261 ± 0.169
1.83AlaTyr: 1.83 ± 0.427
0.0AlaXaa: 0.0 ± 0.0
Cys
0.523CysAla: 0.523 ± 0.593
0.523CysCys: 0.523 ± 0.205
1.307CysAsp: 1.307 ± 0.497
1.046CysGlu: 1.046 ± 0.446
0.0CysPhe: 0.0 ± 0.0
0.784CysGly: 0.784 ± 0.508
0.0CysHis: 0.0 ± 0.0
1.569CysIle: 1.569 ± 0.502
1.046CysLys: 1.046 ± 0.598
1.307CysLeu: 1.307 ± 0.497
0.261CysMet: 0.261 ± 0.251
1.046CysAsn: 1.046 ± 0.376
0.523CysPro: 0.523 ± 0.205
0.261CysGln: 0.261 ± 0.28
0.261CysArg: 0.261 ± 0.169
1.046CysSer: 1.046 ± 0.446
0.784CysThr: 0.784 ± 0.251
1.046CysVal: 1.046 ± 0.376
0.0CysTrp: 0.0 ± 0.0
1.046CysTyr: 1.046 ± 0.462
0.0CysXaa: 0.0 ± 0.0
Asp
2.614AspAla: 2.614 ± 0.286
0.784AspCys: 0.784 ± 0.508
2.614AspAsp: 2.614 ± 1.449
2.876AspGlu: 2.876 ± 0.391
2.092AspPhe: 2.092 ± 0.419
2.353AspGly: 2.353 ± 1.057
0.523AspHis: 0.523 ± 0.205
5.229AspIle: 5.229 ± 0.573
4.183AspLys: 4.183 ± 1.084
6.013AspLeu: 6.013 ± 1.694
2.353AspMet: 2.353 ± 0.804
2.876AspAsn: 2.876 ± 0.49
1.83AspPro: 1.83 ± 0.588
2.614AspGln: 2.614 ± 0.286
2.353AspArg: 2.353 ± 0.665
4.183AspSer: 4.183 ± 0.606
2.876AspThr: 2.876 ± 0.87
3.66AspVal: 3.66 ± 1.267
1.046AspTrp: 1.046 ± 0.677
2.614AspTyr: 2.614 ± 0.67
0.0AspXaa: 0.0 ± 0.0
Glu
4.183GluAla: 4.183 ± 1.129
0.784GluCys: 0.784 ± 0.34
2.353GluAsp: 2.353 ± 0.38
5.752GluGlu: 5.752 ± 1.313
3.399GluPhe: 3.399 ± 0.57
2.876GluGly: 2.876 ± 0.929
1.046GluHis: 1.046 ± 0.41
4.706GluIle: 4.706 ± 0.703
3.66GluLys: 3.66 ± 1.604
6.275GluLeu: 6.275 ± 1.604
1.046GluMet: 1.046 ± 0.376
2.614GluAsn: 2.614 ± 0.962
2.353GluPro: 2.353 ± 0.665
5.49GluGln: 5.49 ± 0.534
3.66GluArg: 3.66 ± 0.944
2.092GluSer: 2.092 ± 0.925
3.137GluThr: 3.137 ± 0.502
6.797GluVal: 6.797 ± 2.069
0.0GluTrp: 0.0 ± 0.0
1.046GluTyr: 1.046 ± 0.534
0.0GluXaa: 0.0 ± 0.0
Phe
2.876PheAla: 2.876 ± 1.16
0.523PheCys: 0.523 ± 0.338
3.399PheAsp: 3.399 ± 0.728
2.876PheGlu: 2.876 ± 0.83
1.046PhePhe: 1.046 ± 0.446
2.092PheGly: 2.092 ± 1.115
1.046PheHis: 1.046 ± 0.677
3.137PheIle: 3.137 ± 1.004
2.614PheLys: 2.614 ± 0.489
2.614PheLeu: 2.614 ± 0.752
0.261PheMet: 0.261 ± 0.169
1.83PheAsn: 1.83 ± 0.287
1.569PhePro: 1.569 ± 0.921
2.353PheGln: 2.353 ± 0.898
1.569PheArg: 1.569 ± 0.971
3.137PheSer: 3.137 ± 1.357
1.569PheThr: 1.569 ± 0.303
4.183PheVal: 4.183 ± 1.05
0.261PheTrp: 0.261 ± 0.169
1.046PheTyr: 1.046 ± 0.41
0.0PheXaa: 0.0 ± 0.0
Gly
2.876GlyAla: 2.876 ± 0.915
0.261GlyCys: 0.261 ± 0.348
2.614GlyAsp: 2.614 ± 0.852
4.706GlyGlu: 4.706 ± 1.75
1.307GlyPhe: 1.307 ± 0.426
2.353GlyGly: 2.353 ± 1.456
2.092GlyHis: 2.092 ± 0.825
3.399GlyIle: 3.399 ± 0.82
5.229GlyLys: 5.229 ± 1.076
3.922GlyLeu: 3.922 ± 1.578
1.046GlyMet: 1.046 ± 0.534
1.83GlyAsn: 1.83 ± 0.427
2.092GlyPro: 2.092 ± 0.751
1.83GlyGln: 1.83 ± 0.856
2.092GlyArg: 2.092 ± 0.431
3.399GlySer: 3.399 ± 2.247
2.876GlyThr: 2.876 ± 1.02
3.66GlyVal: 3.66 ± 0.778
0.261GlyTrp: 0.261 ± 0.169
2.353GlyTyr: 2.353 ± 0.547
0.0GlyXaa: 0.0 ± 0.0
His
1.569HisAla: 1.569 ± 0.733
0.261HisCys: 0.261 ± 0.169
0.784HisAsp: 0.784 ± 0.34
1.046HisGlu: 1.046 ± 0.534
1.046HisPhe: 1.046 ± 0.41
1.046HisGly: 1.046 ± 0.677
0.523HisHis: 0.523 ± 0.338
0.784HisIle: 0.784 ± 0.508
1.569HisLys: 1.569 ± 0.679
1.83HisLeu: 1.83 ± 0.848
0.261HisMet: 0.261 ± 0.28
0.784HisAsn: 0.784 ± 0.613
0.784HisPro: 0.784 ± 0.508
0.0HisGln: 0.0 ± 0.0
0.523HisArg: 0.523 ± 0.338
1.569HisSer: 1.569 ± 0.685
1.569HisThr: 1.569 ± 0.431
0.523HisVal: 0.523 ± 0.338
0.523HisTrp: 0.523 ± 0.338
0.784HisTyr: 0.784 ± 0.461
0.0HisXaa: 0.0 ± 0.0
Ile
6.275IleAla: 6.275 ± 1.016
1.569IleCys: 1.569 ± 0.613
4.967IleAsp: 4.967 ± 1.386
2.614IleGlu: 2.614 ± 0.714
2.353IlePhe: 2.353 ± 0.75
4.706IleGly: 4.706 ± 2.058
0.0IleHis: 0.0 ± 0.0
2.353IleIle: 2.353 ± 1.137
7.059IleLys: 7.059 ± 1.43
3.66IleLeu: 3.66 ± 0.166
0.523IleMet: 0.523 ± 0.506
6.536IleAsn: 6.536 ± 1.029
3.922IlePro: 3.922 ± 1.401
2.353IleGln: 2.353 ± 1.325
3.399IleArg: 3.399 ± 0.759
6.013IleSer: 6.013 ± 0.531
5.752IleThr: 5.752 ± 1.213
3.137IleVal: 3.137 ± 1.226
0.261IleTrp: 0.261 ± 0.169
1.83IleTyr: 1.83 ± 0.89
0.0IleXaa: 0.0 ± 0.0
Lys
4.183LysAla: 4.183 ± 0.63
1.307LysCys: 1.307 ± 0.918
3.66LysAsp: 3.66 ± 1.209
3.399LysGlu: 3.399 ± 1.337
2.614LysPhe: 2.614 ± 0.67
3.399LysGly: 3.399 ± 0.814
1.307LysHis: 1.307 ± 0.617
4.967LysIle: 4.967 ± 1.369
3.399LysLys: 3.399 ± 1.337
7.843LysLeu: 7.843 ± 1.812
1.83LysMet: 1.83 ± 0.235
2.614LysAsn: 2.614 ± 0.67
4.183LysPro: 4.183 ± 0.241
3.399LysGln: 3.399 ± 1.604
3.922LysArg: 3.922 ± 1.163
4.183LysSer: 4.183 ± 0.796
4.706LysThr: 4.706 ± 1.507
7.843LysVal: 7.843 ± 2.881
1.307LysTrp: 1.307 ± 0.426
1.83LysTyr: 1.83 ± 0.287
0.0LysXaa: 0.0 ± 0.0
Leu
6.013LeuAla: 6.013 ± 0.81
0.784LeuCys: 0.784 ± 0.251
4.444LeuAsp: 4.444 ± 1.472
7.059LeuGlu: 7.059 ± 0.647
3.137LeuPhe: 3.137 ± 0.906
3.137LeuGly: 3.137 ± 0.113
2.092LeuHis: 2.092 ± 0.751
5.229LeuIle: 5.229 ± 0.547
8.366LeuLys: 8.366 ± 1.764
9.935LeuLeu: 9.935 ± 2.875
0.523LeuMet: 0.523 ± 0.205
5.752LeuAsn: 5.752 ± 1.076
3.66LeuPro: 3.66 ± 1.009
3.137LeuGln: 3.137 ± 1.15
4.967LeuArg: 4.967 ± 2.022
7.582LeuSer: 7.582 ± 0.322
6.797LeuThr: 6.797 ± 0.99
5.229LeuVal: 5.229 ± 1.977
0.523LeuTrp: 0.523 ± 0.338
3.66LeuTyr: 3.66 ± 1.358
0.0LeuXaa: 0.0 ± 0.0
Met
0.523MetAla: 0.523 ± 0.338
0.261MetCys: 0.261 ± 0.28
1.307MetAsp: 1.307 ± 0.385
0.261MetGlu: 0.261 ± 0.169
0.784MetPhe: 0.784 ± 0.461
0.784MetGly: 0.784 ± 0.404
1.046MetHis: 1.046 ± 0.534
0.784MetIle: 0.784 ± 0.508
0.784MetLys: 0.784 ± 0.508
2.876MetLeu: 2.876 ± 0.49
0.784MetMet: 0.784 ± 0.251
1.307MetAsn: 1.307 ± 0.385
0.523MetPro: 0.523 ± 0.205
1.046MetGln: 1.046 ± 0.734
0.784MetArg: 0.784 ± 0.613
1.83MetSer: 1.83 ± 0.588
1.307MetThr: 1.307 ± 1.503
1.046MetVal: 1.046 ± 0.677
0.523MetTrp: 0.523 ± 0.299
0.784MetTyr: 0.784 ± 0.251
0.0MetXaa: 0.0 ± 0.0
Asn
3.922AsnAla: 3.922 ± 0.806
1.307AsnCys: 1.307 ± 0.426
1.569AsnAsp: 1.569 ± 0.733
2.876AsnGlu: 2.876 ± 1.082
4.183AsnPhe: 4.183 ± 1.476
2.353AsnGly: 2.353 ± 0.753
1.569AsnHis: 1.569 ± 1.015
3.922AsnIle: 3.922 ± 0.854
3.66AsnLys: 3.66 ± 1.409
3.66AsnLeu: 3.66 ± 0.843
0.523AsnMet: 0.523 ± 0.205
2.353AsnAsn: 2.353 ± 1.125
1.83AsnPro: 1.83 ± 1.072
1.569AsnGln: 1.569 ± 0.476
2.614AsnArg: 2.614 ± 1.1
3.66AsnSer: 3.66 ± 0.87
3.399AsnThr: 3.399 ± 1.547
4.444AsnVal: 4.444 ± 1.596
0.261AsnTrp: 0.261 ± 0.348
2.614AsnTyr: 2.614 ± 0.489
0.0AsnXaa: 0.0 ± 0.0
Pro
2.876ProAla: 2.876 ± 1.619
0.523ProCys: 0.523 ± 0.299
1.046ProAsp: 1.046 ± 0.357
1.83ProGlu: 1.83 ± 1.292
2.614ProPhe: 2.614 ± 0.752
2.092ProGly: 2.092 ± 0.745
0.523ProHis: 0.523 ± 0.338
4.183ProIle: 4.183 ± 2.24
2.353ProLys: 2.353 ± 1.064
3.66ProLeu: 3.66 ± 2.406
0.784ProMet: 0.784 ± 0.251
1.83ProAsn: 1.83 ± 0.51
1.83ProPro: 1.83 ± 0.704
1.569ProGln: 1.569 ± 0.921
1.83ProArg: 1.83 ± 0.855
3.922ProSer: 3.922 ± 1.054
2.614ProThr: 2.614 ± 1.43
4.706ProVal: 4.706 ± 0.382
1.307ProTrp: 1.307 ± 0.656
1.307ProTyr: 1.307 ± 0.331
0.0ProXaa: 0.0 ± 0.0
Gln
2.353GlnAla: 2.353 ± 0.458
0.523GlnCys: 0.523 ± 0.695
3.66GlnAsp: 3.66 ± 0.574
1.83GlnGlu: 1.83 ± 0.758
1.046GlnPhe: 1.046 ± 0.41
2.614GlnGly: 2.614 ± 1.025
1.046GlnHis: 1.046 ± 0.677
2.353GlnIle: 2.353 ± 0.344
3.399GlnLys: 3.399 ± 1.13
3.399GlnLeu: 3.399 ± 0.86
1.046GlnMet: 1.046 ± 0.357
1.83GlnAsn: 1.83 ± 1.067
1.83GlnPro: 1.83 ± 0.631
3.137GlnGln: 3.137 ± 1.213
2.614GlnArg: 2.614 ± 0.286
3.137GlnSer: 3.137 ± 0.654
1.569GlnThr: 1.569 ± 0.303
2.876GlnVal: 2.876 ± 1.061
0.261GlnTrp: 0.261 ± 0.28
1.307GlnTyr: 1.307 ± 0.655
0.0GlnXaa: 0.0 ± 0.0
Arg
2.092ArgAla: 2.092 ± 0.745
0.261ArgCys: 0.261 ± 0.28
4.183ArgAsp: 4.183 ± 1.518
2.092ArgGlu: 2.092 ± 0.37
2.876ArgPhe: 2.876 ± 0.597
2.092ArgGly: 2.092 ± 0.751
1.046ArgHis: 1.046 ± 0.41
4.183ArgIle: 4.183 ± 1.79
5.752ArgLys: 5.752 ± 3.757
4.967ArgLeu: 4.967 ± 1.128
1.307ArgMet: 1.307 ± 0.526
2.614ArgAsn: 2.614 ± 0.863
1.307ArgPro: 1.307 ± 0.715
2.092ArgGln: 2.092 ± 0.37
2.614ArgArg: 2.614 ± 0.39
3.399ArgSer: 3.399 ± 1.157
2.092ArgThr: 2.092 ± 0.764
2.092ArgVal: 2.092 ± 0.569
0.523ArgTrp: 0.523 ± 0.412
1.046ArgTyr: 1.046 ± 0.918
0.0ArgXaa: 0.0 ± 0.0
Ser
3.137SerAla: 3.137 ± 1.23
0.523SerCys: 0.523 ± 0.205
5.49SerAsp: 5.49 ± 1.04
5.49SerGlu: 5.49 ± 0.737
2.614SerPhe: 2.614 ± 0.339
4.967SerGly: 4.967 ± 1.236
1.046SerHis: 1.046 ± 0.185
3.922SerIle: 3.922 ± 2.044
4.444SerLys: 4.444 ± 1.55
7.843SerLeu: 7.843 ± 1.014
2.092SerMet: 2.092 ± 0.668
4.444SerAsn: 4.444 ± 1.507
3.399SerPro: 3.399 ± 1.252
2.353SerGln: 2.353 ± 1.568
4.183SerArg: 4.183 ± 1.236
5.229SerSer: 5.229 ± 0.726
4.444SerThr: 4.444 ± 1.344
5.752SerVal: 5.752 ± 0.944
0.784SerTrp: 0.784 ± 0.34
1.569SerTyr: 1.569 ± 0.358
0.0SerXaa: 0.0 ± 0.0
Thr
3.922ThrAla: 3.922 ± 1.566
0.784ThrCys: 0.784 ± 0.271
3.399ThrAsp: 3.399 ± 1.057
3.922ThrGlu: 3.922 ± 1.49
2.092ThrPhe: 2.092 ± 0.376
3.399ThrGly: 3.399 ± 0.873
0.261ThrHis: 0.261 ± 0.348
3.66ThrIle: 3.66 ± 1.052
3.399ThrLys: 3.399 ± 0.84
6.797ThrLeu: 6.797 ± 0.975
0.784ThrMet: 0.784 ± 0.508
3.922ThrAsn: 3.922 ± 0.854
2.614ThrPro: 2.614 ± 1.293
2.092ThrGln: 2.092 ± 0.743
3.399ThrArg: 3.399 ± 1.28
4.183ThrSer: 4.183 ± 0.726
9.15ThrThr: 9.15 ± 2.026
5.229ThrVal: 5.229 ± 1.143
1.83ThrTrp: 1.83 ± 0.526
2.353ThrTyr: 2.353 ± 0.713
0.0ThrXaa: 0.0 ± 0.0
Val
3.922ValAla: 3.922 ± 0.786
1.83ValCys: 1.83 ± 0.616
3.66ValAsp: 3.66 ± 1.185
4.967ValGlu: 4.967 ± 1.104
2.353ValPhe: 2.353 ± 0.775
4.967ValGly: 4.967 ± 1.16
2.092ValHis: 2.092 ± 0.376
5.229ValIle: 5.229 ± 1.923
4.967ValLys: 4.967 ± 1.986
5.229ValLeu: 5.229 ± 1.505
1.307ValMet: 1.307 ± 0.331
3.922ValAsn: 3.922 ± 1.4
4.706ValPro: 4.706 ± 1.644
2.353ValGln: 2.353 ± 0.754
1.83ValArg: 1.83 ± 0.432
7.059ValSer: 7.059 ± 0.945
6.013ValThr: 6.013 ± 0.369
5.49ValVal: 5.49 ± 1.236
1.307ValTrp: 1.307 ± 0.461
2.092ValTyr: 2.092 ± 1.148
0.0ValXaa: 0.0 ± 0.0
Trp
0.261TrpAla: 0.261 ± 0.169
0.523TrpCys: 0.523 ± 0.338
0.261TrpAsp: 0.261 ± 0.169
0.523TrpGlu: 0.523 ± 0.412
0.0TrpPhe: 0.0 ± 0.0
0.523TrpGly: 0.523 ± 0.412
0.0TrpHis: 0.0 ± 0.0
1.569TrpIle: 1.569 ± 0.453
1.307TrpLys: 1.307 ± 0.526
0.523TrpLeu: 0.523 ± 0.338
0.523TrpMet: 0.523 ± 0.205
0.261TrpAsn: 0.261 ± 0.348
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.523TrpArg: 0.523 ± 0.205
1.046TrpSer: 1.046 ± 0.41
2.092TrpThr: 2.092 ± 0.37
0.784TrpVal: 0.784 ± 0.271
0.0TrpTrp: 0.0 ± 0.0
1.046TrpTyr: 1.046 ± 0.376
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.307TyrAla: 1.307 ± 0.385
0.261TyrCys: 0.261 ± 0.28
1.569TyrAsp: 1.569 ± 0.41
2.876TyrGlu: 2.876 ± 0.745
1.046TyrPhe: 1.046 ± 0.446
1.83TyrGly: 1.83 ± 1.184
0.523TyrHis: 0.523 ± 0.205
2.353TyrIle: 2.353 ± 0.216
1.569TyrLys: 1.569 ± 0.615
3.66TyrLeu: 3.66 ± 0.835
1.046TyrMet: 1.046 ± 0.376
0.784TyrAsn: 0.784 ± 0.34
1.307TyrPro: 1.307 ± 0.787
1.569TyrGln: 1.569 ± 1.237
1.83TyrArg: 1.83 ± 0.62
2.614TyrSer: 2.614 ± 0.781
2.353TyrThr: 2.353 ± 0.216
3.137TyrVal: 3.137 ± 0.953
0.523TyrTrp: 0.523 ± 0.338
1.569TyrTyr: 1.569 ± 0.685
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3826 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski