Amino acid dipepetide frequency for Wuhan cricket virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.526AlaAla: 4.526 ± 1.528
0.647AlaCys: 0.647 ± 0.54
2.586AlaAsp: 2.586 ± 0.75
1.617AlaGlu: 1.617 ± 0.767
2.263AlaPhe: 2.263 ± 1.174
4.203AlaGly: 4.203 ± 0.738
1.617AlaHis: 1.617 ± 0.473
4.526AlaIle: 4.526 ± 1.053
5.173AlaLys: 5.173 ± 1.767
5.173AlaLeu: 5.173 ± 0.983
1.293AlaMet: 1.293 ± 0.531
1.617AlaAsn: 1.617 ± 0.619
1.293AlaPro: 1.293 ± 0.858
1.617AlaGln: 1.617 ± 0.619
1.617AlaArg: 1.617 ± 0.292
3.88AlaSer: 3.88 ± 1.303
4.526AlaThr: 4.526 ± 0.803
3.233AlaVal: 3.233 ± 1.059
1.293AlaTrp: 1.293 ± 0.331
2.586AlaTyr: 2.586 ± 0.685
0.0AlaXaa: 0.0 ± 0.0
Cys
0.647CysAla: 0.647 ± 0.452
0.323CysCys: 0.323 ± 0.295
0.647CysAsp: 0.647 ± 0.348
0.647CysGlu: 0.647 ± 0.26
0.323CysPhe: 0.323 ± 0.295
1.617CysGly: 1.617 ± 0.968
0.0CysHis: 0.0 ± 0.0
1.617CysIle: 1.617 ± 0.736
0.323CysLys: 0.323 ± 0.27
3.556CysLeu: 3.556 ± 1.539
0.647CysMet: 0.647 ± 0.26
0.323CysAsn: 0.323 ± 0.295
1.293CysPro: 1.293 ± 0.869
0.0CysGln: 0.0 ± 0.0
0.323CysArg: 0.323 ± 0.3
0.97CysSer: 0.97 ± 0.525
0.323CysThr: 0.323 ± 0.295
1.617CysVal: 1.617 ± 0.896
0.0CysTrp: 0.0 ± 0.0
0.647CysTyr: 0.647 ± 0.434
0.0CysXaa: 0.0 ± 0.0
Asp
2.91AspAla: 2.91 ± 0.654
0.323AspCys: 0.323 ± 0.27
3.233AspAsp: 3.233 ± 0.962
4.203AspGlu: 4.203 ± 1.264
3.556AspPhe: 3.556 ± 0.876
2.263AspGly: 2.263 ± 0.816
1.293AspHis: 1.293 ± 0.769
2.586AspIle: 2.586 ± 1.06
1.617AspLys: 1.617 ± 0.708
3.88AspLeu: 3.88 ± 0.845
2.586AspMet: 2.586 ± 0.41
1.293AspAsn: 1.293 ± 0.633
2.586AspPro: 2.586 ± 1.234
0.323AspGln: 0.323 ± 0.3
1.293AspArg: 1.293 ± 0.416
1.617AspSer: 1.617 ± 1.349
3.88AspThr: 3.88 ± 0.687
3.556AspVal: 3.556 ± 0.819
1.293AspTrp: 1.293 ± 0.468
1.617AspTyr: 1.617 ± 0.555
0.0AspXaa: 0.0 ± 0.0
Glu
0.647GluAla: 0.647 ± 0.54
0.97GluCys: 0.97 ± 0.272
1.94GluAsp: 1.94 ± 0.607
3.233GluGlu: 3.233 ± 0.801
2.91GluPhe: 2.91 ± 1.074
2.91GluGly: 2.91 ± 1.067
1.617GluHis: 1.617 ± 0.563
3.556GluIle: 3.556 ± 1.347
3.233GluLys: 3.233 ± 1.065
6.143GluLeu: 6.143 ± 1.575
2.586GluMet: 2.586 ± 0.955
2.91GluAsn: 2.91 ± 0.726
1.94GluPro: 1.94 ± 0.738
0.647GluGln: 0.647 ± 0.26
1.94GluArg: 1.94 ± 0.78
3.233GluSer: 3.233 ± 0.737
1.94GluThr: 1.94 ± 0.47
3.233GluVal: 3.233 ± 0.551
0.647GluTrp: 0.647 ± 0.434
2.263GluTyr: 2.263 ± 0.585
0.0GluXaa: 0.0 ± 0.0
Phe
2.91PheAla: 2.91 ± 0.584
1.617PheCys: 1.617 ± 0.666
1.94PheAsp: 1.94 ± 0.666
1.617PheGlu: 1.617 ± 1.072
1.617PhePhe: 1.617 ± 0.567
3.233PheGly: 3.233 ± 0.897
1.617PheHis: 1.617 ± 1.312
1.94PheIle: 1.94 ± 0.845
2.586PheLys: 2.586 ± 0.686
3.556PheLeu: 3.556 ± 0.661
2.586PheMet: 2.586 ± 0.452
1.617PheAsn: 1.617 ± 0.638
0.647PhePro: 0.647 ± 0.384
0.647PheGln: 0.647 ± 0.452
1.617PheArg: 1.617 ± 1.312
3.233PheSer: 3.233 ± 1.189
2.91PheThr: 2.91 ± 0.654
2.263PheVal: 2.263 ± 0.634
0.0PheTrp: 0.0 ± 0.0
1.293PheTyr: 1.293 ± 0.677
0.0PheXaa: 0.0 ± 0.0
Gly
3.556GlyAla: 3.556 ± 1.113
1.293GlyCys: 1.293 ± 0.526
2.263GlyAsp: 2.263 ± 1.16
5.82GlyGlu: 5.82 ± 2.164
5.82GlyPhe: 5.82 ± 1.702
5.82GlyGly: 5.82 ± 1.73
2.91GlyHis: 2.91 ± 0.714
5.496GlyIle: 5.496 ± 1.155
2.91GlyLys: 2.91 ± 0.798
8.083GlyLeu: 8.083 ± 1.0
2.263GlyMet: 2.263 ± 0.314
2.91GlyAsn: 2.91 ± 0.633
2.263GlyPro: 2.263 ± 0.434
2.91GlyGln: 2.91 ± 0.502
2.91GlyArg: 2.91 ± 1.2
6.466GlySer: 6.466 ± 0.475
3.233GlyThr: 3.233 ± 0.78
3.233GlyVal: 3.233 ± 0.817
1.94GlyTrp: 1.94 ± 0.738
3.233GlyTyr: 3.233 ± 1.408
0.0GlyXaa: 0.0 ± 0.0
His
1.617HisAla: 1.617 ± 1.013
0.0HisCys: 0.0 ± 0.0
0.97HisAsp: 0.97 ± 0.272
1.293HisGlu: 1.293 ± 0.552
1.617HisPhe: 1.617 ± 0.482
0.647HisGly: 0.647 ± 0.26
1.293HisHis: 1.293 ± 0.686
0.647HisIle: 0.647 ± 0.433
0.647HisLys: 0.647 ± 0.384
2.91HisLeu: 2.91 ± 1.264
0.323HisMet: 0.323 ± 0.437
1.94HisAsn: 1.94 ± 0.895
0.97HisPro: 0.97 ± 0.401
0.647HisGln: 0.647 ± 0.348
1.293HisArg: 1.293 ± 0.593
2.586HisSer: 2.586 ± 0.705
1.94HisThr: 1.94 ± 0.248
2.586HisVal: 2.586 ± 1.04
0.647HisTrp: 0.647 ± 0.348
1.617HisTyr: 1.617 ± 0.567
0.0HisXaa: 0.0 ± 0.0
Ile
4.203IleAla: 4.203 ± 1.462
0.647IleCys: 0.647 ± 0.6
2.91IleAsp: 2.91 ± 0.794
3.233IleGlu: 3.233 ± 0.876
1.94IlePhe: 1.94 ± 0.979
3.88IleGly: 3.88 ± 1.239
2.263IleHis: 2.263 ± 0.532
5.173IleIle: 5.173 ± 0.596
1.94IleLys: 1.94 ± 0.894
8.406IleLeu: 8.406 ± 2.806
3.233IleMet: 3.233 ± 0.779
4.203IleAsn: 4.203 ± 1.347
3.233IlePro: 3.233 ± 0.797
1.94IleGln: 1.94 ± 0.287
4.526IleArg: 4.526 ± 2.003
4.526IleSer: 4.526 ± 0.986
4.203IleThr: 4.203 ± 1.688
5.173IleVal: 5.173 ± 0.751
0.97IleTrp: 0.97 ± 0.514
3.233IleTyr: 3.233 ± 0.98
0.0IleXaa: 0.0 ± 0.0
Lys
3.88LysAla: 3.88 ± 1.104
0.323LysCys: 0.323 ± 0.262
1.94LysAsp: 1.94 ± 0.441
1.94LysGlu: 1.94 ± 0.441
2.263LysPhe: 2.263 ± 0.752
3.88LysGly: 3.88 ± 2.061
1.617LysHis: 1.617 ± 0.638
1.293LysIle: 1.293 ± 0.526
2.586LysLys: 2.586 ± 1.078
4.203LysLeu: 4.203 ± 1.198
1.293LysMet: 1.293 ± 0.351
1.94LysAsn: 1.94 ± 0.786
2.263LysPro: 2.263 ± 0.816
1.617LysGln: 1.617 ± 0.697
2.586LysArg: 2.586 ± 0.471
3.88LysSer: 3.88 ± 1.048
3.88LysThr: 3.88 ± 0.436
2.586LysVal: 2.586 ± 0.673
0.97LysTrp: 0.97 ± 0.408
1.617LysTyr: 1.617 ± 0.733
0.0LysXaa: 0.0 ± 0.0
Leu
7.113LeuAla: 7.113 ± 0.818
2.263LeuCys: 2.263 ± 0.327
4.203LeuAsp: 4.203 ± 1.207
3.556LeuGlu: 3.556 ± 1.086
3.556LeuPhe: 3.556 ± 0.661
8.083LeuGly: 8.083 ± 1.271
1.617LeuHis: 1.617 ± 0.367
8.729LeuIle: 8.729 ± 2.518
4.203LeuLys: 4.203 ± 1.313
9.699LeuLeu: 9.699 ± 1.911
5.82LeuMet: 5.82 ± 1.101
5.496LeuAsn: 5.496 ± 1.73
4.526LeuPro: 4.526 ± 0.825
2.263LeuGln: 2.263 ± 0.401
4.526LeuArg: 4.526 ± 0.395
5.82LeuSer: 5.82 ± 1.521
7.113LeuThr: 7.113 ± 1.312
8.729LeuVal: 8.729 ± 1.816
1.293LeuTrp: 1.293 ± 0.864
2.586LeuTyr: 2.586 ± 0.663
0.0LeuXaa: 0.0 ± 0.0
Met
2.586MetAla: 2.586 ± 0.728
0.323MetCys: 0.323 ± 0.3
1.617MetAsp: 1.617 ± 0.54
2.263MetGlu: 2.263 ± 0.603
0.97MetPhe: 0.97 ± 0.373
3.556MetGly: 3.556 ± 1.205
1.617MetHis: 1.617 ± 0.367
3.233MetIle: 3.233 ± 0.807
1.617MetLys: 1.617 ± 0.697
3.88MetLeu: 3.88 ± 1.565
0.323MetMet: 0.323 ± 0.3
1.617MetAsn: 1.617 ± 0.473
1.94MetPro: 1.94 ± 0.929
1.293MetGln: 1.293 ± 0.686
2.91MetArg: 2.91 ± 0.691
1.94MetSer: 1.94 ± 0.441
1.94MetThr: 1.94 ± 0.606
3.88MetVal: 3.88 ± 1.139
0.0MetTrp: 0.0 ± 0.0
0.97MetTyr: 0.97 ± 0.683
0.0MetXaa: 0.0 ± 0.0
Asn
0.97AsnAla: 0.97 ± 0.214
0.97AsnCys: 0.97 ± 0.885
2.91AsnAsp: 2.91 ± 0.678
1.293AsnGlu: 1.293 ± 0.351
1.293AsnPhe: 1.293 ± 0.695
3.233AsnGly: 3.233 ± 1.661
0.647AsnHis: 0.647 ± 0.348
4.526AsnIle: 4.526 ± 1.753
0.647AsnLys: 0.647 ± 0.384
4.203AsnLeu: 4.203 ± 1.682
2.586AsnMet: 2.586 ± 0.88
1.94AsnAsn: 1.94 ± 0.654
2.586AsnPro: 2.586 ± 0.663
0.323AsnGln: 0.323 ± 0.27
0.97AsnArg: 0.97 ± 0.666
4.85AsnSer: 4.85 ± 0.987
4.203AsnThr: 4.203 ± 1.215
2.586AsnVal: 2.586 ± 0.588
0.97AsnTrp: 0.97 ± 0.214
2.263AsnTyr: 2.263 ± 0.946
0.0AsnXaa: 0.0 ± 0.0
Pro
1.94ProAla: 1.94 ± 0.918
0.323ProCys: 0.323 ± 0.27
0.97ProAsp: 0.97 ± 0.579
2.263ProGlu: 2.263 ± 0.721
1.617ProPhe: 1.617 ± 0.319
3.88ProGly: 3.88 ± 0.779
0.97ProHis: 0.97 ± 0.541
4.526ProIle: 4.526 ± 0.466
0.97ProLys: 0.97 ± 0.488
2.263ProLeu: 2.263 ± 0.946
1.293ProMet: 1.293 ± 0.552
1.293ProAsn: 1.293 ± 0.552
4.526ProPro: 4.526 ± 1.367
0.647ProGln: 0.647 ± 0.338
1.617ProArg: 1.617 ± 0.92
4.203ProSer: 4.203 ± 2.377
5.173ProThr: 5.173 ± 0.884
3.88ProVal: 3.88 ± 0.966
0.97ProTrp: 0.97 ± 0.447
1.94ProTyr: 1.94 ± 0.78
0.0ProXaa: 0.0 ± 0.0
Gln
1.293GlnAla: 1.293 ± 0.226
0.0GlnCys: 0.0 ± 0.0
1.617GlnAsp: 1.617 ± 0.319
0.97GlnGlu: 0.97 ± 0.408
0.97GlnPhe: 0.97 ± 0.373
1.617GlnGly: 1.617 ± 0.968
0.647GlnHis: 0.647 ± 0.26
2.91GlnIle: 2.91 ± 0.633
0.647GlnLys: 0.647 ± 0.348
1.94GlnLeu: 1.94 ± 0.936
0.647GlnMet: 0.647 ± 0.406
0.647GlnAsn: 0.647 ± 0.26
0.323GlnPro: 0.323 ± 0.27
0.647GlnGln: 0.647 ± 0.525
1.94GlnArg: 1.94 ± 0.248
2.91GlnSer: 2.91 ± 0.785
0.323GlnThr: 0.323 ± 0.27
3.233GlnVal: 3.233 ± 0.874
0.647GlnTrp: 0.647 ± 0.419
1.293GlnTyr: 1.293 ± 0.351
0.0GlnXaa: 0.0 ± 0.0
Arg
2.263ArgAla: 2.263 ± 1.015
0.97ArgCys: 0.97 ± 0.382
2.91ArgAsp: 2.91 ± 1.386
3.233ArgGlu: 3.233 ± 1.573
1.293ArgPhe: 1.293 ± 0.52
4.203ArgGly: 4.203 ± 0.547
0.97ArgHis: 0.97 ± 0.408
5.173ArgIle: 5.173 ± 0.716
2.586ArgLys: 2.586 ± 0.813
2.586ArgLeu: 2.586 ± 1.078
1.617ArgMet: 1.617 ± 0.683
3.556ArgAsn: 3.556 ± 1.019
2.263ArgPro: 2.263 ± 0.399
1.293ArgGln: 1.293 ± 0.721
2.91ArgArg: 2.91 ± 0.642
4.85ArgSer: 4.85 ± 0.428
0.647ArgThr: 0.647 ± 0.26
5.82ArgVal: 5.82 ± 0.636
0.647ArgTrp: 0.647 ± 0.348
1.617ArgTyr: 1.617 ± 0.48
0.0ArgXaa: 0.0 ± 0.0
Ser
2.586SerAla: 2.586 ± 0.903
0.647SerCys: 0.647 ± 0.338
3.88SerAsp: 3.88 ± 0.898
1.94SerGlu: 1.94 ± 0.369
2.91SerPhe: 2.91 ± 0.937
5.82SerGly: 5.82 ± 1.558
1.293SerHis: 1.293 ± 0.505
2.586SerIle: 2.586 ± 1.052
5.82SerLys: 5.82 ± 1.11
9.053SerLeu: 9.053 ± 2.385
1.94SerMet: 1.94 ± 0.735
3.233SerAsn: 3.233 ± 0.826
3.88SerPro: 3.88 ± 1.161
2.91SerGln: 2.91 ± 0.707
7.759SerArg: 7.759 ± 1.564
7.113SerSer: 7.113 ± 2.313
3.233SerThr: 3.233 ± 0.871
4.203SerVal: 4.203 ± 1.475
2.263SerTrp: 2.263 ± 0.67
4.85SerTyr: 4.85 ± 1.147
0.0SerXaa: 0.0 ± 0.0
Thr
2.586ThrAla: 2.586 ± 0.787
0.647ThrCys: 0.647 ± 0.452
4.203ThrAsp: 4.203 ± 0.96
3.88ThrGlu: 3.88 ± 1.007
0.323ThrPhe: 0.323 ± 0.27
4.203ThrGly: 4.203 ± 0.973
0.323ThrHis: 0.323 ± 0.295
3.556ThrIle: 3.556 ± 0.258
4.203ThrLys: 4.203 ± 0.547
6.79ThrLeu: 6.79 ± 0.642
2.263ThrMet: 2.263 ± 0.493
2.263ThrAsn: 2.263 ± 0.65
2.91ThrPro: 2.91 ± 0.937
1.617ThrGln: 1.617 ± 0.421
5.173ThrArg: 5.173 ± 1.059
4.526ThrSer: 4.526 ± 1.344
7.113ThrThr: 7.113 ± 1.469
1.617ThrVal: 1.617 ± 0.304
0.647ThrTrp: 0.647 ± 0.491
3.88ThrTyr: 3.88 ± 1.052
0.0ThrXaa: 0.0 ± 0.0
Val
3.233ValAla: 3.233 ± 1.059
2.586ValCys: 2.586 ± 1.05
2.91ValAsp: 2.91 ± 0.747
2.91ValGlu: 2.91 ± 0.73
2.91ValPhe: 2.91 ± 0.678
8.083ValGly: 8.083 ± 1.7
1.94ValHis: 1.94 ± 0.673
3.556ValIle: 3.556 ± 1.124
1.94ValLys: 1.94 ± 0.369
8.083ValLeu: 8.083 ± 1.184
2.91ValMet: 2.91 ± 1.001
1.617ValAsn: 1.617 ± 0.666
2.263ValPro: 2.263 ± 0.698
1.94ValGln: 1.94 ± 0.479
3.233ValArg: 3.233 ± 1.695
6.143ValSer: 6.143 ± 1.197
2.91ValThr: 2.91 ± 0.656
2.586ValVal: 2.586 ± 0.788
1.293ValTrp: 1.293 ± 0.593
4.526ValTyr: 4.526 ± 0.888
0.0ValXaa: 0.0 ± 0.0
Trp
0.647TrpAla: 0.647 ± 0.26
0.97TrpCys: 0.97 ± 0.653
0.323TrpAsp: 0.323 ± 0.262
0.97TrpGlu: 0.97 ± 0.408
0.97TrpPhe: 0.97 ± 0.575
1.293TrpGly: 1.293 ± 0.226
0.323TrpHis: 0.323 ± 0.295
1.293TrpIle: 1.293 ± 0.727
1.293TrpLys: 1.293 ± 1.049
1.617TrpLeu: 1.617 ± 0.968
1.293TrpMet: 1.293 ± 0.52
0.97TrpAsn: 0.97 ± 0.566
0.323TrpPro: 0.323 ± 0.3
0.323TrpGln: 0.323 ± 0.27
0.647TrpArg: 0.647 ± 0.338
1.94TrpSer: 1.94 ± 1.238
0.647TrpThr: 0.647 ± 0.433
1.293TrpVal: 1.293 ± 0.643
0.97TrpTrp: 0.97 ± 0.899
0.647TrpTyr: 0.647 ± 0.419
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.173TyrAla: 5.173 ± 0.857
0.0TyrCys: 0.0 ± 0.0
2.263TyrAsp: 2.263 ± 1.16
1.617TyrGlu: 1.617 ± 0.563
0.323TyrPhe: 0.323 ± 0.262
2.91TyrGly: 2.91 ± 0.967
1.617TyrHis: 1.617 ± 0.319
2.91TyrIle: 2.91 ± 1.171
1.617TyrLys: 1.617 ± 0.71
5.173TyrLeu: 5.173 ± 0.751
0.647TyrMet: 0.647 ± 0.26
2.586TyrAsn: 2.586 ± 0.903
3.233TyrPro: 3.233 ± 0.584
1.617TyrGln: 1.617 ± 0.516
1.617TyrArg: 1.617 ± 0.37
3.233TyrSer: 3.233 ± 0.979
2.586TyrThr: 2.586 ± 0.834
2.263TyrVal: 2.263 ± 0.65
1.293TyrTrp: 1.293 ± 0.633
1.94TyrTyr: 1.94 ± 1.151
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3094 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski