Amino acid dipepetide frequency for Colletotrichum gloeosporioides (strain Cg-14) (Anthracnose fungus) (Glomerella cingulata)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.306AlaAla: 10.306 ± 0.058	1.155AlaCys: 1.155 ± 0.015	4.628AlaAsp: 4.628 ± 0.031	5.335AlaGlu: 5.335 ± 0.036	3.385AlaPhe: 3.385 ± 0.025	6.372AlaGly: 6.372 ± 0.037	1.721AlaHis: 1.721 ± 0.016	4.439AlaIle: 4.439 ± 0.027	4.298AlaLys: 4.298 ± 0.032	7.834AlaLeu: 7.834 ± 0.044	2.186AlaMet: 2.186 ± 0.019	3.208AlaAsn: 3.208 ± 0.023	4.959AlaPro: 4.959 ± 0.039	3.37AlaGln: 3.37 ± 0.026	4.758AlaArg: 4.758 ± 0.029	7.322AlaSer: 7.322 ± 0.044	5.574AlaThr: 5.574 ± 0.039	5.949AlaVal: 5.949 ± 0.034	1.349AlaTrp: 1.349 ± 0.014	2.278AlaTyr: 2.278 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.981CysAla: 0.981 ± 0.012	0.256CysCys: 0.256 ± 0.007	0.698CysAsp: 0.698 ± 0.011	0.6CysGlu: 0.6 ± 0.011	0.555CysPhe: 0.555 ± 0.009	1.003CysGly: 1.003 ± 0.014	0.324CysHis: 0.324 ± 0.008	0.71CysIle: 0.71 ± 0.011	0.53CysLys: 0.53 ± 0.009	1.226CysLeu: 1.226 ± 0.016	0.29CysMet: 0.29 ± 0.006	0.473CysAsn: 0.473 ± 0.01	0.679CysPro: 0.679 ± 0.011	0.439CysGln: 0.439 ± 0.009	0.737CysArg: 0.737 ± 0.012	0.891CysSer: 0.891 ± 0.01	0.709CysThr: 0.709 ± 0.01	0.825CysVal: 0.825 ± 0.011	0.232CysTrp: 0.232 ± 0.006	0.374CysTyr: 0.374 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.064AspAla: 5.064 ± 0.037	0.669AspCys: 0.669 ± 0.01	4.451AspAsp: 4.451 ± 0.04	4.493AspGlu: 4.493 ± 0.036	2.398AspPhe: 2.398 ± 0.019	4.439AspGly: 4.439 ± 0.033	1.227AspHis: 1.227 ± 0.015	3.029AspIle: 3.029 ± 0.022	2.515AspLys: 2.515 ± 0.022	5.077AspLeu: 5.077 ± 0.028	1.35AspMet: 1.35 ± 0.014	1.961AspAsn: 1.961 ± 0.02	3.323AspPro: 3.323 ± 0.021	1.819AspGln: 1.819 ± 0.017	2.975AspArg: 2.975 ± 0.024	3.891AspSer: 3.891 ± 0.026	2.948AspThr: 2.948 ± 0.019	3.947AspVal: 3.947 ± 0.026	0.999AspTrp: 0.999 ± 0.012	1.631AspTyr: 1.631 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.579GluAla: 5.579 ± 0.038	0.611GluCys: 0.611 ± 0.01	4.206GluAsp: 4.206 ± 0.032	5.146GluGlu: 5.146 ± 0.042	2.001GluPhe: 2.001 ± 0.02	3.775GluGly: 3.775 ± 0.026	1.356GluHis: 1.356 ± 0.015	2.953GluIle: 2.953 ± 0.022	3.745GluLys: 3.745 ± 0.029	4.964GluLeu: 4.964 ± 0.035	1.531GluMet: 1.531 ± 0.017	2.269GluAsn: 2.269 ± 0.02	2.777GluPro: 2.777 ± 0.027	2.268GluGln: 2.268 ± 0.022	3.666GluArg: 3.666 ± 0.031	3.952GluSer: 3.952 ± 0.027	3.45GluThr: 3.45 ± 0.027	3.69GluVal: 3.69 ± 0.026	0.959GluTrp: 0.959 ± 0.013	1.651GluTyr: 1.651 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.347PheAla: 3.347 ± 0.026	0.597PheCys: 0.597 ± 0.009	2.443PheAsp: 2.443 ± 0.017	2.243PheGlu: 2.243 ± 0.019	1.784PhePhe: 1.784 ± 0.021	3.138PheGly: 3.138 ± 0.026	0.91PheHis: 0.91 ± 0.011	1.909PheIle: 1.909 ± 0.018	1.629PheLys: 1.629 ± 0.015	3.506PheLeu: 3.506 ± 0.027	0.888PheMet: 0.888 ± 0.012	1.567PheAsn: 1.567 ± 0.015	2.002PhePro: 2.002 ± 0.019	1.421PheGln: 1.421 ± 0.014	1.992PheArg: 1.992 ± 0.016	2.982PheSer: 2.982 ± 0.022	2.277PheThr: 2.277 ± 0.022	2.579PheVal: 2.579 ± 0.021	0.725PheTrp: 0.725 ± 0.012	1.186PheTyr: 1.186 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.878GlyAla: 5.878 ± 0.036	0.965GlyCys: 0.965 ± 0.013	3.815GlyAsp: 3.815 ± 0.03	3.589GlyGlu: 3.589 ± 0.028	3.081GlyPhe: 3.081 ± 0.025	6.205GlyGly: 6.205 ± 0.048	1.703GlyHis: 1.703 ± 0.015	3.669GlyIle: 3.669 ± 0.027	3.508GlyLys: 3.508 ± 0.025	6.342GlyLeu: 6.342 ± 0.038	1.734GlyMet: 1.734 ± 0.016	2.728GlyAsn: 2.728 ± 0.023	3.433GlyPro: 3.433 ± 0.026	2.536GlyGln: 2.536 ± 0.021	4.083GlyArg: 4.083 ± 0.028	5.664GlySer: 5.664 ± 0.034	4.212GlyThr: 4.212 ± 0.028	4.75GlyVal: 4.75 ± 0.032	1.313GlyTrp: 1.313 ± 0.014	2.234GlyTyr: 2.234 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.807HisAla: 1.807 ± 0.02	0.336HisCys: 0.336 ± 0.008	1.302HisAsp: 1.302 ± 0.014	1.29HisGlu: 1.29 ± 0.015	0.957HisPhe: 0.957 ± 0.012	1.696HisGly: 1.696 ± 0.017	0.809HisHis: 0.809 ± 0.015	1.137HisIle: 1.137 ± 0.013	0.884HisLys: 0.884 ± 0.012	2.117HisLeu: 2.117 ± 0.02	0.528HisMet: 0.528 ± 0.008	0.838HisAsn: 0.838 ± 0.011	1.543HisPro: 1.543 ± 0.016	0.921HisGln: 0.921 ± 0.013	1.425HisArg: 1.425 ± 0.015	1.608HisSer: 1.608 ± 0.019	1.168HisThr: 1.168 ± 0.015	1.459HisVal: 1.459 ± 0.017	0.373HisTrp: 0.373 ± 0.008	0.686HisTyr: 0.686 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.35IleAla: 4.35 ± 0.025	0.74IleCys: 0.74 ± 0.011	2.906IleAsp: 2.906 ± 0.023	2.776IleGlu: 2.776 ± 0.02	2.068IlePhe: 2.068 ± 0.022	3.396IleGly: 3.396 ± 0.028	1.158IleHis: 1.158 ± 0.014	2.602IleIle: 2.602 ± 0.024	2.193IleLys: 2.193 ± 0.017	4.453IleLeu: 4.453 ± 0.028	1.103IleMet: 1.103 ± 0.013	1.85IleAsn: 1.85 ± 0.017	2.942IlePro: 2.942 ± 0.022	1.826IleGln: 1.826 ± 0.016	2.664IleArg: 2.664 ± 0.019	3.605IleSer: 3.605 ± 0.024	2.891IleThr: 2.891 ± 0.024	3.295IleVal: 3.295 ± 0.026	0.805IleTrp: 0.805 ± 0.012	1.362IleTyr: 1.362 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.497LysAla: 4.497 ± 0.03	0.493LysCys: 0.493 ± 0.009	2.947LysAsp: 2.947 ± 0.023	3.316LysGlu: 3.316 ± 0.028	1.559LysPhe: 1.559 ± 0.013	3.081LysGly: 3.081 ± 0.024	1.126LysHis: 1.126 ± 0.014	2.259LysIle: 2.259 ± 0.02	3.304LysLys: 3.304 ± 0.039	4.035LysLeu: 4.035 ± 0.027	1.072LysMet: 1.072 ± 0.014	1.767LysAsn: 1.767 ± 0.019	2.686LysPro: 2.686 ± 0.024	1.751LysGln: 1.751 ± 0.016	3.149LysArg: 3.149 ± 0.023	3.367LysSer: 3.367 ± 0.026	2.983LysThr: 2.983 ± 0.022	2.91LysVal: 2.91 ± 0.022	0.741LysTrp: 0.741 ± 0.011	1.422LysTyr: 1.422 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	8.076LeuAla: 8.076 ± 0.042	1.178LeuCys: 1.178 ± 0.013	5.078LeuAsp: 5.078 ± 0.027	5.274LeuGlu: 5.274 ± 0.034	3.369LeuPhe: 3.369 ± 0.027	6.159LeuGly: 6.159 ± 0.031	2.092LeuHis: 2.092 ± 0.019	3.872LeuIle: 3.872 ± 0.029	4.11LeuLys: 4.11 ± 0.027	8.004LeuLeu: 8.004 ± 0.05	1.895LeuMet: 1.895 ± 0.016	3.097LeuAsn: 3.097 ± 0.02	5.322LeuPro: 5.322 ± 0.034	3.526LeuGln: 3.526 ± 0.027	5.497LeuArg: 5.497 ± 0.035	6.783LeuSer: 6.783 ± 0.036	4.742LeuThr: 4.742 ± 0.031	5.535LeuVal: 5.535 ± 0.034	1.32LeuTrp: 1.32 ± 0.015	2.318LeuTyr: 2.318 ± 0.018	0.0LeuXaa: 0.0 ± 0.0
Met	2.466MetAla: 2.466 ± 0.021	0.264MetCys: 0.264 ± 0.007	1.301MetAsp: 1.301 ± 0.013	1.318MetGlu: 1.318 ± 0.015	0.856MetPhe: 0.856 ± 0.012	1.566MetGly: 1.566 ± 0.017	0.498MetHis: 0.498 ± 0.009	1.05MetIle: 1.05 ± 0.013	1.1MetLys: 1.1 ± 0.015	1.939MetLeu: 1.939 ± 0.017	0.654MetMet: 0.654 ± 0.01	0.86MetAsn: 0.86 ± 0.011	1.343MetPro: 1.343 ± 0.016	0.828MetGln: 0.828 ± 0.013	1.337MetArg: 1.337 ± 0.014	1.955MetSer: 1.955 ± 0.019	1.413MetThr: 1.413 ± 0.014	1.413MetVal: 1.413 ± 0.015	0.312MetTrp: 0.312 ± 0.008	0.57MetTyr: 0.57 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.274AsnAla: 3.274 ± 0.023	0.476AsnCys: 0.476 ± 0.009	2.091AsnAsp: 2.091 ± 0.02	1.965AsnGlu: 1.965 ± 0.018	1.519AsnPhe: 1.519 ± 0.015	3.2AsnGly: 3.2 ± 0.029	0.838AsnHis: 0.838 ± 0.012	2.052AsnIle: 2.052 ± 0.017	1.568AsnLys: 1.568 ± 0.016	3.265AsnLeu: 3.265 ± 0.023	0.908AsnMet: 0.908 ± 0.011	1.565AsnAsn: 1.565 ± 0.02	2.422AsnPro: 2.422 ± 0.019	1.297AsnGln: 1.297 ± 0.015	1.843AsnArg: 1.843 ± 0.018	2.614AsnSer: 2.614 ± 0.022	2.237AsnThr: 2.237 ± 0.02	2.431AsnVal: 2.431 ± 0.02	0.621AsnTrp: 0.621 ± 0.009	1.091AsnTyr: 1.091 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	5.511ProAla: 5.511 ± 0.039	0.493ProCys: 0.493 ± 0.009	3.302ProAsp: 3.302 ± 0.02	3.941ProGlu: 3.941 ± 0.029	2.098ProPhe: 2.098 ± 0.018	4.036ProGly: 4.036 ± 0.029	1.183ProHis: 1.183 ± 0.016	2.475ProIle: 2.475 ± 0.022	2.727ProLys: 2.727 ± 0.025	4.492ProLeu: 4.492 ± 0.026	1.13ProMet: 1.13 ± 0.015	2.218ProAsn: 2.218 ± 0.017	4.809ProPro: 4.809 ± 0.058	2.324ProGln: 2.324 ± 0.026	3.199ProArg: 3.199 ± 0.028	5.32ProSer: 5.32 ± 0.039	3.827ProThr: 3.827 ± 0.029	3.584ProVal: 3.584 ± 0.026	0.86ProTrp: 0.86 ± 0.013	1.504ProTyr: 1.504 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.433GlnAla: 3.433 ± 0.024	0.436GlnCys: 0.436 ± 0.009	1.985GlnAsp: 1.985 ± 0.017	2.244GlnGlu: 2.244 ± 0.018	1.256GlnPhe: 1.256 ± 0.014	2.336GlnGly: 2.336 ± 0.019	0.992GlnHis: 0.992 ± 0.013	1.794GlnIle: 1.794 ± 0.017	1.885GlnLys: 1.885 ± 0.018	3.233GlnLeu: 3.233 ± 0.025	0.918GlnMet: 0.918 ± 0.014	1.471GlnAsn: 1.471 ± 0.019	2.45GlnPro: 2.45 ± 0.025	2.281GlnGln: 2.281 ± 0.042	2.4GlnArg: 2.4 ± 0.021	2.761GlnSer: 2.761 ± 0.023	2.235GlnThr: 2.235 ± 0.021	2.149GlnVal: 2.149 ± 0.015	0.581GlnTrp: 0.581 ± 0.01	1.127GlnTyr: 1.127 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.497ArgAla: 4.497 ± 0.029	0.68ArgCys: 0.68 ± 0.011	3.363ArgAsp: 3.363 ± 0.029	3.621ArgGlu: 3.621 ± 0.028	2.16ArgPhe: 2.16 ± 0.016	3.624ArgGly: 3.624 ± 0.032	1.464ArgHis: 1.464 ± 0.016	2.775ArgIle: 2.775 ± 0.021	3.205ArgLys: 3.205 ± 0.026	5.198ArgLeu: 5.198 ± 0.034	1.334ArgMet: 1.334 ± 0.013	2.149ArgAsn: 2.149 ± 0.017	3.29ArgPro: 3.29 ± 0.03	2.463ArgGln: 2.463 ± 0.021	4.687ArgArg: 4.687 ± 0.039	4.239ArgSer: 4.239 ± 0.033	3.042ArgThr: 3.042 ± 0.023	3.323ArgVal: 3.323 ± 0.023	0.994ArgTrp: 0.994 ± 0.012	1.641ArgTyr: 1.641 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.537SerAla: 6.537 ± 0.038	0.884SerCys: 0.884 ± 0.014	4.102SerAsp: 4.102 ± 0.024	3.87SerGlu: 3.87 ± 0.024	3.073SerPhe: 3.073 ± 0.022	5.525SerGly: 5.525 ± 0.036	1.729SerHis: 1.729 ± 0.021	3.798SerIle: 3.798 ± 0.027	3.556SerLys: 3.556 ± 0.025	6.733SerLeu: 6.733 ± 0.036	1.748SerMet: 1.748 ± 0.016	2.845SerAsn: 2.845 ± 0.022	4.953SerPro: 4.953 ± 0.043	2.947SerGln: 2.947 ± 0.025	4.41SerArg: 4.41 ± 0.032	7.629SerSer: 7.629 ± 0.054	5.135SerThr: 5.135 ± 0.036	4.573SerVal: 4.573 ± 0.03	1.233SerTrp: 1.233 ± 0.013	2.032SerTyr: 2.032 ± 0.017	0.0SerXaa: 0.0 ± 0.0
Thr	5.471ThrAla: 5.471 ± 0.03	0.778ThrCys: 0.778 ± 0.013	2.911ThrAsp: 2.911 ± 0.028	3.14ThrGlu: 3.14 ± 0.024	2.368ThrPhe: 2.368 ± 0.018	4.296ThrGly: 4.296 ± 0.034	1.218ThrHis: 1.218 ± 0.013	3.152ThrIle: 3.152 ± 0.03	2.677ThrLys: 2.677 ± 0.024	5.031ThrLeu: 5.031 ± 0.029	1.254ThrMet: 1.254 ± 0.014	2.201ThrAsn: 2.201 ± 0.018	4.203ThrPro: 4.203 ± 0.031	1.993ThrGln: 1.993 ± 0.018	2.943ThrArg: 2.943 ± 0.022	5.009ThrSer: 5.009 ± 0.039	4.359ThrThr: 4.359 ± 0.044	3.886ThrVal: 3.886 ± 0.03	0.996ThrTrp: 0.996 ± 0.014	1.737ThrTyr: 1.737 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.762ValAla: 5.762 ± 0.031	0.872ValCys: 0.872 ± 0.012	3.903ValAsp: 3.903 ± 0.025	3.924ValGlu: 3.924 ± 0.027	2.734ValPhe: 2.734 ± 0.021	4.311ValGly: 4.311 ± 0.027	1.373ValHis: 1.373 ± 0.014	3.106ValIle: 3.106 ± 0.022	3.011ValLys: 3.011 ± 0.022	5.715ValLeu: 5.715 ± 0.03	1.425ValMet: 1.425 ± 0.013	2.34ValAsn: 2.34 ± 0.02	3.675ValPro: 3.675 ± 0.03	2.297ValGln: 2.297 ± 0.02	3.388ValArg: 3.388 ± 0.022	4.621ValSer: 4.621 ± 0.031	3.75ValThr: 3.75 ± 0.031	4.659ValVal: 4.659 ± 0.035	1.013ValTrp: 1.013 ± 0.014	1.832ValTyr: 1.832 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.313TrpAla: 1.313 ± 0.013	0.22TrpCys: 0.22 ± 0.006	1.005TrpAsp: 1.005 ± 0.012	0.916TrpGlu: 0.916 ± 0.013	0.644TrpPhe: 0.644 ± 0.011	1.071TrpGly: 1.071 ± 0.012	0.398TrpHis: 0.398 ± 0.008	0.825TrpIle: 0.825 ± 0.011	0.882TrpLys: 0.882 ± 0.012	1.469TrpLeu: 1.469 ± 0.015	0.429TrpMet: 0.429 ± 0.008	0.713TrpAsn: 0.713 ± 0.012	0.729TrpPro: 0.729 ± 0.011	0.607TrpGln: 0.607 ± 0.009	0.999TrpArg: 0.999 ± 0.014	1.14TrpSer: 1.14 ± 0.013	1.063TrpThr: 1.063 ± 0.014	1.01TrpVal: 1.01 ± 0.013	0.323TrpTrp: 0.323 ± 0.009	0.513TrpTyr: 0.513 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.278TyrAla: 2.278 ± 0.02	0.428TyrCys: 0.428 ± 0.008	1.766TyrAsp: 1.766 ± 0.02	1.547TyrGlu: 1.547 ± 0.017	1.261TyrPhe: 1.261 ± 0.014	2.212TyrGly: 2.212 ± 0.022	0.764TyrHis: 0.764 ± 0.012	1.379TyrIle: 1.379 ± 0.014	1.14TyrLys: 1.14 ± 0.014	2.617TyrLeu: 2.617 ± 0.02	0.664TyrMet: 0.664 ± 0.01	1.156TyrAsn: 1.156 ± 0.014	1.495TyrPro: 1.495 ± 0.016	1.052TyrGln: 1.052 ± 0.013	1.599TyrArg: 1.599 ± 0.015	1.958TyrSer: 1.958 ± 0.017	1.609TyrThr: 1.609 ± 0.016	1.746TyrVal: 1.746 ± 0.018	0.518TyrTrp: 0.518 ± 0.01	0.963TyrTyr: 0.963 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 16388 proteins (6823665 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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