Amino acid dipepetide frequency for Beihai sobemo-like virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.358AlaAla: 14.358 ± 1.446
1.436AlaCys: 1.436 ± 0.721
2.872AlaAsp: 2.872 ± 1.442
10.05AlaGlu: 10.05 ± 2.164
5.743AlaPhe: 5.743 ± 0.002
13.64AlaGly: 13.64 ± 0.355
2.872AlaHis: 2.872 ± 1.439
2.872AlaIle: 2.872 ± 1.439
2.872AlaLys: 2.872 ± 1.442
11.486AlaLeu: 11.486 ± 1.436
1.436AlaMet: 1.436 ± 0.721
5.743AlaAsn: 5.743 ± 2.879
6.461AlaPro: 6.461 ± 2.519
5.025AlaGln: 5.025 ± 0.358
8.615AlaArg: 8.615 ± 1.444
10.05AlaSer: 10.05 ± 0.724
2.154AlaThr: 2.154 ± 1.081
5.743AlaVal: 5.743 ± 0.002
2.154AlaTrp: 2.154 ± 1.081
2.154AlaTyr: 2.154 ± 0.359
0.0AlaXaa: 0.0 ± 0.0
Cys
0.718CysAla: 0.718 ± 0.36
0.0CysCys: 0.0 ± 0.0
0.718CysAsp: 0.718 ± 0.36
1.436CysGlu: 1.436 ± 0.721
0.0CysPhe: 0.0 ± 0.0
0.718CysGly: 0.718 ± 1.08
0.0CysHis: 0.0 ± 0.0
1.436CysIle: 1.436 ± 2.16
0.718CysLys: 0.718 ± 0.36
0.718CysLeu: 0.718 ± 0.36
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.436CysArg: 1.436 ± 0.721
0.0CysSer: 0.0 ± 0.0
3.589CysThr: 3.589 ± 0.361
2.154CysVal: 2.154 ± 0.359
0.718CysTrp: 0.718 ± 0.36
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.461AspAla: 6.461 ± 1.803
0.0AspCys: 0.0 ± 0.0
3.589AspAsp: 3.589 ± 1.802
2.872AspGlu: 2.872 ± 1.442
0.718AspPhe: 0.718 ± 0.36
7.179AspGly: 7.179 ± 0.718
0.718AspHis: 0.718 ± 0.36
2.154AspIle: 2.154 ± 0.359
2.872AspLys: 2.872 ± 0.001
3.589AspLeu: 3.589 ± 2.52
1.436AspMet: 1.436 ± 0.589
1.436AspAsn: 1.436 ± 0.721
3.589AspPro: 3.589 ± 0.361
0.718AspGln: 0.718 ± 0.36
3.589AspArg: 3.589 ± 0.361
2.154AspSer: 2.154 ± 1.081
1.436AspThr: 1.436 ± 0.721
3.589AspVal: 3.589 ± 1.802
0.718AspTrp: 0.718 ± 0.36
2.154AspTyr: 2.154 ± 1.081
0.0AspXaa: 0.0 ± 0.0
Glu
9.332GluAla: 9.332 ± 1.804
0.0GluCys: 0.0 ± 0.0
2.154GluAsp: 2.154 ± 0.359
4.307GluGlu: 4.307 ± 2.162
2.872GluPhe: 2.872 ± 0.001
6.461GluGly: 6.461 ± 0.362
0.0GluHis: 0.0 ± 0.0
1.436GluIle: 1.436 ± 0.721
2.872GluLys: 2.872 ± 1.442
3.589GluLeu: 3.589 ± 1.802
0.718GluMet: 0.718 ± 0.36
0.718GluAsn: 0.718 ± 1.08
2.872GluPro: 2.872 ± 1.442
2.872GluGln: 2.872 ± 1.442
2.154GluArg: 2.154 ± 0.359
5.743GluSer: 5.743 ± 2.883
2.154GluThr: 2.154 ± 0.359
3.589GluVal: 3.589 ± 1.802
0.718GluTrp: 0.718 ± 1.08
2.872GluTyr: 2.872 ± 1.442
0.0GluXaa: 0.0 ± 0.0
Phe
3.589PheAla: 3.589 ± 1.079
0.718PheCys: 0.718 ± 0.36
2.872PheAsp: 2.872 ± 0.001
3.589PheGlu: 3.589 ± 1.802
1.436PhePhe: 1.436 ± 0.721
6.461PheGly: 6.461 ± 0.362
0.0PheHis: 0.0 ± 0.0
2.154PheIle: 2.154 ± 0.359
0.718PheLys: 0.718 ± 0.36
5.743PheLeu: 5.743 ± 1.443
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.718PhePro: 0.718 ± 1.08
2.154PheGln: 2.154 ± 0.359
1.436PheArg: 1.436 ± 0.72
3.589PheSer: 3.589 ± 3.96
2.872PheThr: 2.872 ± 1.442
5.025PheVal: 5.025 ± 1.082
0.0PheTrp: 0.0 ± 0.0
1.436PheTyr: 1.436 ± 0.721
0.0PheXaa: 0.0 ± 0.0
Gly
11.486GlyAla: 11.486 ± 2.885
2.154GlyCys: 2.154 ± 0.359
4.307GlyAsp: 4.307 ± 0.722
4.307GlyGlu: 4.307 ± 0.719
3.589GlyPhe: 3.589 ± 1.079
9.332GlyGly: 9.332 ± 1.804
2.872GlyHis: 2.872 ± 0.001
5.025GlyIle: 5.025 ± 1.082
2.872GlyLys: 2.872 ± 1.439
9.332GlyLeu: 9.332 ± 1.804
0.718GlyMet: 0.718 ± 0.307
2.872GlyAsn: 2.872 ± 0.001
4.307GlyPro: 4.307 ± 0.722
1.436GlyGln: 1.436 ± 0.721
5.743GlyArg: 5.743 ± 1.438
5.025GlySer: 5.025 ± 1.799
3.589GlyThr: 3.589 ± 2.52
12.922GlyVal: 12.922 ± 0.716
3.589GlyTrp: 3.589 ± 1.079
2.154GlyTyr: 2.154 ± 1.081
0.0GlyXaa: 0.0 ± 0.0
His
1.436HisAla: 1.436 ± 0.721
0.718HisCys: 0.718 ± 0.36
2.154HisAsp: 2.154 ± 1.081
0.718HisGlu: 0.718 ± 0.36
2.154HisPhe: 2.154 ± 1.081
1.436HisGly: 1.436 ± 2.16
1.436HisHis: 1.436 ± 0.72
0.718HisIle: 0.718 ± 0.36
0.0HisLys: 0.0 ± 0.0
0.718HisLeu: 0.718 ± 1.08
0.0HisMet: 0.0 ± 0.0
0.718HisAsn: 0.718 ± 0.36
0.0HisPro: 0.0 ± 0.0
0.718HisGln: 0.718 ± 0.36
2.154HisArg: 2.154 ± 0.359
0.718HisSer: 0.718 ± 0.36
1.436HisThr: 1.436 ± 0.721
0.718HisVal: 0.718 ± 0.36
0.718HisTrp: 0.718 ± 0.36
2.154HisTyr: 2.154 ± 0.359
0.0HisXaa: 0.0 ± 0.0
Ile
2.872IleAla: 2.872 ± 1.439
0.0IleCys: 0.0 ± 0.0
1.436IleAsp: 1.436 ± 0.72
4.307IleGlu: 4.307 ± 2.162
0.0IlePhe: 0.0 ± 0.0
2.154IleGly: 2.154 ± 1.081
0.718IleHis: 0.718 ± 0.36
1.436IleIle: 1.436 ± 0.721
0.718IleLys: 0.718 ± 0.36
4.307IleLeu: 4.307 ± 2.159
0.0IleMet: 0.0 ± 0.0
0.718IleAsn: 0.718 ± 1.08
0.718IlePro: 0.718 ± 0.36
0.718IleGln: 0.718 ± 1.08
2.154IleArg: 2.154 ± 1.081
0.718IleSer: 0.718 ± 0.36
4.307IleThr: 4.307 ± 3.6
3.589IleVal: 3.589 ± 0.361
1.436IleTrp: 1.436 ± 0.721
0.718IleTyr: 0.718 ± 1.08
0.0IleXaa: 0.0 ± 0.0
Lys
3.589LysAla: 3.589 ± 1.802
0.0LysCys: 0.0 ± 0.0
1.436LysAsp: 1.436 ± 0.721
2.154LysGlu: 2.154 ± 1.081
2.154LysPhe: 2.154 ± 0.359
2.154LysGly: 2.154 ± 0.359
1.436LysHis: 1.436 ± 0.721
0.718LysIle: 0.718 ± 0.36
2.154LysLys: 2.154 ± 0.359
2.154LysLeu: 2.154 ± 0.359
1.436LysMet: 1.436 ± 0.72
0.718LysAsn: 0.718 ± 0.36
2.154LysPro: 2.154 ± 1.081
2.154LysGln: 2.154 ± 1.081
4.307LysArg: 4.307 ± 0.722
2.872LysSer: 2.872 ± 0.001
1.436LysThr: 1.436 ± 0.72
4.307LysVal: 4.307 ± 2.162
0.0LysTrp: 0.0 ± 0.0
0.718LysTyr: 0.718 ± 0.36
0.0LysXaa: 0.0 ± 0.0
Leu
8.615LeuAla: 8.615 ± 2.878
0.718LeuCys: 0.718 ± 0.36
5.025LeuAsp: 5.025 ± 1.082
2.872LeuGlu: 2.872 ± 1.442
2.872LeuPhe: 2.872 ± 1.442
11.486LeuGly: 11.486 ± 1.445
0.718LeuHis: 0.718 ± 0.36
2.872LeuIle: 2.872 ± 0.001
3.589LeuLys: 3.589 ± 0.361
5.025LeuLeu: 5.025 ± 2.523
0.718LeuMet: 0.718 ± 1.08
2.872LeuAsn: 2.872 ± 2.88
6.461LeuPro: 6.461 ± 2.519
3.589LeuGln: 3.589 ± 1.079
4.307LeuArg: 4.307 ± 0.722
7.179LeuSer: 7.179 ± 0.718
5.743LeuThr: 5.743 ± 0.002
4.307LeuVal: 4.307 ± 2.162
2.154LeuTrp: 2.154 ± 0.359
3.589LeuTyr: 3.589 ± 1.802
0.0LeuXaa: 0.0 ± 0.0
Met
5.025MetAla: 5.025 ± 1.799
0.718MetCys: 0.718 ± 1.08
0.0MetAsp: 0.0 ± 0.0
0.718MetGlu: 0.718 ± 0.36
2.154MetPhe: 2.154 ± 1.081
0.718MetGly: 0.718 ± 0.36
0.0MetHis: 0.0 ± 0.0
0.718MetIle: 0.718 ± 1.08
0.718MetLys: 0.718 ± 0.36
2.154MetLeu: 2.154 ± 0.359
0.718MetMet: 0.718 ± 0.36
1.436MetAsn: 1.436 ± 2.16
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
0.718MetSer: 0.718 ± 1.08
0.718MetThr: 0.718 ± 0.36
2.154MetVal: 2.154 ± 0.359
0.0MetTrp: 0.0 ± 0.0
0.718MetTyr: 0.718 ± 0.36
0.0MetXaa: 0.0 ± 0.0
Asn
2.872AsnAla: 2.872 ± 1.439
0.0AsnCys: 0.0 ± 0.0
2.154AsnAsp: 2.154 ± 1.081
0.0AsnGlu: 0.0 ± 0.0
1.436AsnPhe: 1.436 ± 0.72
2.154AsnGly: 2.154 ± 3.24
0.0AsnHis: 0.0 ± 0.0
1.436AsnIle: 1.436 ± 0.72
3.589AsnLys: 3.589 ± 0.361
2.154AsnLeu: 2.154 ± 1.081
0.718AsnMet: 0.718 ± 1.08
0.718AsnAsn: 0.718 ± 1.08
2.154AsnPro: 2.154 ± 0.359
1.436AsnGln: 1.436 ± 2.16
4.307AsnArg: 4.307 ± 0.719
2.154AsnSer: 2.154 ± 0.359
1.436AsnThr: 1.436 ± 0.72
2.154AsnVal: 2.154 ± 1.8
0.0AsnTrp: 0.0 ± 0.0
0.718AsnTyr: 0.718 ± 0.36
0.0AsnXaa: 0.0 ± 0.0
Pro
5.025ProAla: 5.025 ± 0.358
0.718ProCys: 0.718 ± 0.36
2.154ProAsp: 2.154 ± 0.359
5.025ProGlu: 5.025 ± 0.358
1.436ProPhe: 1.436 ± 2.16
4.307ProGly: 4.307 ± 0.722
2.154ProHis: 2.154 ± 1.081
2.872ProIle: 2.872 ± 1.442
0.0ProLys: 0.0 ± 0.0
4.307ProLeu: 4.307 ± 2.159
1.436ProMet: 1.436 ± 2.16
1.436ProAsn: 1.436 ± 0.721
7.179ProPro: 7.179 ± 0.723
0.718ProGln: 0.718 ± 0.36
2.872ProArg: 2.872 ± 2.88
3.589ProSer: 3.589 ± 0.361
2.872ProThr: 2.872 ± 0.001
4.307ProVal: 4.307 ± 0.722
0.0ProTrp: 0.0 ± 0.0
0.718ProTyr: 0.718 ± 1.08
0.0ProXaa: 0.0 ± 0.0
Gln
2.872GlnAla: 2.872 ± 1.439
0.0GlnCys: 0.0 ± 0.0
5.025GlnAsp: 5.025 ± 0.358
0.718GlnGlu: 0.718 ± 1.08
0.718GlnPhe: 0.718 ± 0.36
3.589GlnGly: 3.589 ± 2.52
1.436GlnHis: 1.436 ± 0.721
2.154GlnIle: 2.154 ± 1.8
2.154GlnLys: 2.154 ± 1.081
5.025GlnLeu: 5.025 ± 1.082
2.154GlnMet: 2.154 ± 0.359
0.718GlnAsn: 0.718 ± 0.36
0.0GlnPro: 0.0 ± 0.0
0.718GlnGln: 0.718 ± 0.36
0.0GlnArg: 0.0 ± 0.0
0.718GlnSer: 0.718 ± 0.36
2.154GlnThr: 2.154 ± 1.8
2.872GlnVal: 2.872 ± 0.001
0.0GlnTrp: 0.0 ± 0.0
1.436GlnTyr: 1.436 ± 0.721
0.0GlnXaa: 0.0 ± 0.0
Arg
4.307ArgAla: 4.307 ± 0.722
1.436ArgCys: 1.436 ± 0.721
3.589ArgAsp: 3.589 ± 1.802
2.872ArgGlu: 2.872 ± 1.442
5.025ArgPhe: 5.025 ± 0.358
1.436ArgGly: 1.436 ± 0.72
2.872ArgHis: 2.872 ± 0.001
1.436ArgIle: 1.436 ± 0.721
2.872ArgLys: 2.872 ± 1.442
9.332ArgLeu: 9.332 ± 3.244
1.436ArgMet: 1.436 ± 0.72
2.154ArgAsn: 2.154 ± 1.8
3.589ArgPro: 3.589 ± 2.52
2.872ArgGln: 2.872 ± 1.442
6.461ArgArg: 6.461 ± 3.959
5.743ArgSer: 5.743 ± 0.002
2.872ArgThr: 2.872 ± 1.439
3.589ArgVal: 3.589 ± 3.96
0.718ArgTrp: 0.718 ± 0.36
1.436ArgTyr: 1.436 ± 0.721
0.0ArgXaa: 0.0 ± 0.0
Ser
15.075SerAla: 15.075 ± 2.515
0.0SerCys: 0.0 ± 0.0
4.307SerAsp: 4.307 ± 0.722
2.872SerGlu: 2.872 ± 0.001
3.589SerPhe: 3.589 ± 1.802
7.179SerGly: 7.179 ± 0.723
0.718SerHis: 0.718 ± 0.36
0.718SerIle: 0.718 ± 1.08
0.0SerLys: 0.0 ± 0.0
2.872SerLeu: 2.872 ± 1.442
1.436SerMet: 1.436 ± 0.72
2.872SerAsn: 2.872 ± 1.439
2.872SerPro: 2.872 ± 0.001
0.718SerGln: 0.718 ± 0.36
2.872SerArg: 2.872 ± 1.442
0.718SerSer: 0.718 ± 0.36
4.307SerThr: 4.307 ± 0.719
5.025SerVal: 5.025 ± 0.358
1.436SerTrp: 1.436 ± 0.721
2.154SerTyr: 2.154 ± 1.8
0.0SerXaa: 0.0 ± 0.0
Thr
7.179ThrAla: 7.179 ± 0.723
2.872ThrCys: 2.872 ± 0.001
0.718ThrAsp: 0.718 ± 0.36
2.872ThrGlu: 2.872 ± 0.001
1.436ThrPhe: 1.436 ± 0.72
5.743ThrGly: 5.743 ± 1.443
0.718ThrHis: 0.718 ± 1.08
2.154ThrIle: 2.154 ± 0.359
3.589ThrLys: 3.589 ± 1.802
2.154ThrLeu: 2.154 ± 1.8
2.154ThrMet: 2.154 ± 1.081
2.872ThrAsn: 2.872 ± 0.001
2.154ThrPro: 2.154 ± 1.081
1.436ThrGln: 1.436 ± 2.16
3.589ThrArg: 3.589 ± 0.361
2.154ThrSer: 2.154 ± 1.8
2.872ThrThr: 2.872 ± 2.88
2.154ThrVal: 2.154 ± 1.8
2.154ThrTrp: 2.154 ± 3.24
0.718ThrTyr: 0.718 ± 1.08
0.0ThrXaa: 0.0 ± 0.0
Val
8.615ValAla: 8.615 ± 1.444
2.154ValCys: 2.154 ± 0.359
2.872ValAsp: 2.872 ± 0.001
2.872ValGlu: 2.872 ± 1.442
5.743ValPhe: 5.743 ± 0.002
10.768ValGly: 10.768 ± 1.084
1.436ValHis: 1.436 ± 0.721
0.0ValIle: 0.0 ± 0.0
4.307ValLys: 4.307 ± 0.722
5.743ValLeu: 5.743 ± 0.002
0.0ValMet: 0.0 ± 0.0
1.436ValAsn: 1.436 ± 0.721
4.307ValPro: 4.307 ± 0.719
5.025ValGln: 5.025 ± 3.239
4.307ValArg: 4.307 ± 0.719
3.589ValSer: 3.589 ± 0.361
3.589ValThr: 3.589 ± 1.079
5.743ValVal: 5.743 ± 0.002
1.436ValTrp: 1.436 ± 0.721
2.154ValTyr: 2.154 ± 1.081
0.0ValXaa: 0.0 ± 0.0
Trp
2.154TrpAla: 2.154 ± 0.359
0.0TrpCys: 0.0 ± 0.0
1.436TrpAsp: 1.436 ± 0.72
2.154TrpGlu: 2.154 ± 0.359
0.718TrpPhe: 0.718 ± 0.36
0.718TrpGly: 0.718 ± 0.36
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.718TrpLys: 0.718 ± 1.08
0.718TrpLeu: 0.718 ± 0.36
0.718TrpMet: 0.718 ± 0.36
0.718TrpAsn: 0.718 ± 1.08
1.436TrpPro: 1.436 ± 0.721
1.436TrpGln: 1.436 ± 0.72
2.154TrpArg: 2.154 ± 0.359
1.436TrpSer: 1.436 ± 0.721
0.718TrpThr: 0.718 ± 0.36
0.718TrpVal: 0.718 ± 0.36
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.154TyrAla: 2.154 ± 1.081
0.718TyrCys: 0.718 ± 1.08
2.154TyrAsp: 2.154 ± 1.081
0.718TyrGlu: 0.718 ± 0.36
0.718TyrPhe: 0.718 ± 1.08
0.718TyrGly: 0.718 ± 0.36
0.718TyrHis: 0.718 ± 0.36
0.718TyrIle: 0.718 ± 0.36
0.718TyrLys: 0.718 ± 0.36
3.589TyrLeu: 3.589 ± 1.079
1.436TyrMet: 1.436 ± 0.72
1.436TyrAsn: 1.436 ± 0.721
2.154TyrPro: 2.154 ± 1.8
0.718TyrGln: 0.718 ± 0.36
3.589TyrArg: 3.589 ± 1.802
2.872TyrSer: 2.872 ± 1.442
1.436TyrThr: 1.436 ± 0.721
1.436TyrVal: 1.436 ± 0.721
0.0TyrTrp: 0.0 ± 0.0
0.718TyrTyr: 0.718 ± 0.36
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1394 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski