Amino acid dipepetide frequency for Erigeron breviscapus amalgavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.729AlaAla: 9.729 ± 1.782
1.39AlaCys: 1.39 ± 0.764
4.17AlaAsp: 4.17 ± 1.986
3.475AlaGlu: 3.475 ± 0.942
2.085AlaPhe: 2.085 ± 0.28
10.424AlaGly: 10.424 ± 4.251
0.695AlaHis: 0.695 ± 1.044
2.78AlaIle: 2.78 ± 1.324
3.475AlaLys: 3.475 ± 0.942
10.424AlaLeu: 10.424 ± 1.452
2.78AlaMet: 2.78 ± 0.102
1.39AlaAsn: 1.39 ± 0.662
3.475AlaPro: 3.475 ± 0.942
4.864AlaGln: 4.864 ± 0.178
8.339AlaArg: 8.339 ± 3.971
5.559AlaSer: 5.559 ± 1.222
2.085AlaThr: 2.085 ± 0.28
7.644AlaVal: 7.644 ± 0.076
2.78AlaTrp: 2.78 ± 0.102
2.085AlaTyr: 2.085 ± 0.28
0.0AlaXaa: 0.0 ± 0.0
Cys
0.695CysAla: 0.695 ± 0.382
0.695CysCys: 0.695 ± 0.382
0.0CysAsp: 0.0 ± 0.0
1.39CysGlu: 1.39 ± 0.662
2.085CysPhe: 2.085 ± 1.146
3.475CysGly: 3.475 ± 0.942
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.39CysLys: 1.39 ± 0.662
2.78CysLeu: 2.78 ± 0.102
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.695CysArg: 0.695 ± 0.382
2.085CysSer: 2.085 ± 1.146
1.39CysThr: 1.39 ± 0.662
0.695CysVal: 0.695 ± 0.382
0.695CysTrp: 0.695 ± 0.382
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.864AspAla: 4.864 ± 0.178
2.085AspCys: 2.085 ± 0.28
4.864AspAsp: 4.864 ± 0.178
3.475AspGlu: 3.475 ± 0.484
4.17AspPhe: 4.17 ± 0.866
2.78AspGly: 2.78 ± 0.102
0.695AspHis: 0.695 ± 0.382
0.0AspIle: 0.0 ± 0.0
2.78AspLys: 2.78 ± 1.324
9.729AspLeu: 9.729 ± 0.356
0.695AspMet: 0.695 ± 0.382
2.085AspAsn: 2.085 ± 1.146
2.085AspPro: 2.085 ± 0.28
1.39AspGln: 1.39 ± 0.662
4.17AspArg: 4.17 ± 0.866
2.78AspSer: 2.78 ± 1.528
1.39AspThr: 1.39 ± 0.764
4.17AspVal: 4.17 ± 0.56
1.39AspTrp: 1.39 ± 0.764
2.78AspTyr: 2.78 ± 0.102
0.0AspXaa: 0.0 ± 0.0
Glu
11.119GluAla: 11.119 ± 0.408
1.39GluCys: 1.39 ± 0.764
5.559GluAsp: 5.559 ± 3.056
5.559GluGlu: 5.559 ± 4.073
4.17GluPhe: 4.17 ± 1.986
4.864GluGly: 4.864 ± 0.178
0.695GluHis: 0.695 ± 0.382
2.78GluIle: 2.78 ± 0.102
2.78GluLys: 2.78 ± 1.528
2.78GluLeu: 2.78 ± 1.528
2.085GluMet: 2.085 ± 0.28
0.0GluAsn: 0.0 ± 0.0
4.17GluPro: 4.17 ± 1.986
7.644GluGln: 7.644 ± 2.927
7.644GluArg: 7.644 ± 1.35
1.39GluSer: 1.39 ± 2.088
0.695GluThr: 0.695 ± 0.382
4.864GluVal: 4.864 ± 1.604
0.0GluTrp: 0.0 ± 0.0
4.864GluTyr: 4.864 ± 0.178
0.0GluXaa: 0.0 ± 0.0
Phe
4.864PheAla: 4.864 ± 0.178
1.39PheCys: 1.39 ± 0.662
3.475PheAsp: 3.475 ± 0.484
3.475PheGlu: 3.475 ± 0.942
2.78PhePhe: 2.78 ± 0.102
4.864PheGly: 4.864 ± 0.178
1.39PheHis: 1.39 ± 0.764
0.695PheIle: 0.695 ± 0.382
1.39PheLys: 1.39 ± 0.764
2.085PheLeu: 2.085 ± 1.146
0.695PheMet: 0.695 ± 0.382
2.78PheAsn: 2.78 ± 0.102
4.17PhePro: 4.17 ± 0.56
1.39PheGln: 1.39 ± 0.764
3.475PheArg: 3.475 ± 0.942
2.085PheSer: 2.085 ± 0.28
0.695PheThr: 0.695 ± 0.382
2.78PheVal: 2.78 ± 0.102
0.695PheTrp: 0.695 ± 0.382
1.39PheTyr: 1.39 ± 0.662
0.0PheXaa: 0.0 ± 0.0
Gly
5.559GlyAla: 5.559 ± 2.648
0.0GlyCys: 0.0 ± 0.0
6.949GlyAsp: 6.949 ± 1.884
4.17GlyGlu: 4.17 ± 0.866
6.254GlyPhe: 6.254 ± 0.586
9.034GlyGly: 9.034 ± 0.688
0.695GlyHis: 0.695 ± 0.382
3.475GlyIle: 3.475 ± 0.484
3.475GlyLys: 3.475 ± 0.484
8.339GlyLeu: 8.339 ± 0.306
2.78GlyMet: 2.78 ± 0.241
2.78GlyAsn: 2.78 ± 1.324
3.475GlyPro: 3.475 ± 0.484
2.78GlyGln: 2.78 ± 0.102
6.949GlyArg: 6.949 ± 0.968
1.39GlySer: 1.39 ± 0.662
4.17GlyThr: 4.17 ± 0.56
4.17GlyVal: 4.17 ± 0.866
0.695GlyTrp: 0.695 ± 0.382
2.085GlyTyr: 2.085 ± 0.28
0.0GlyXaa: 0.0 ± 0.0
His
0.695HisAla: 0.695 ± 0.382
1.39HisCys: 1.39 ± 0.662
0.0HisAsp: 0.0 ± 0.0
0.695HisGlu: 0.695 ± 0.382
0.695HisPhe: 0.695 ± 0.382
1.39HisGly: 1.39 ± 0.662
1.39HisHis: 1.39 ± 0.764
0.0HisIle: 0.0 ± 0.0
0.695HisLys: 0.695 ± 0.382
2.78HisLeu: 2.78 ± 0.102
0.0HisMet: 0.0 ± 0.0
0.695HisAsn: 0.695 ± 1.044
2.085HisPro: 2.085 ± 1.146
0.0HisGln: 0.0 ± 0.0
2.085HisArg: 2.085 ± 1.146
2.085HisSer: 2.085 ± 0.28
0.0HisThr: 0.0 ± 0.0
1.39HisVal: 1.39 ± 0.764
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.39IleAla: 1.39 ± 0.662
0.695IleCys: 0.695 ± 0.382
4.17IleAsp: 4.17 ± 0.866
3.475IleGlu: 3.475 ± 0.484
3.475IlePhe: 3.475 ± 0.942
2.78IleGly: 2.78 ± 0.102
1.39IleHis: 1.39 ± 0.764
2.085IleIle: 2.085 ± 1.146
0.695IleLys: 0.695 ± 0.382
2.085IleLeu: 2.085 ± 0.28
0.695IleMet: 0.695 ± 0.382
0.0IleAsn: 0.0 ± 0.0
1.39IlePro: 1.39 ± 0.764
0.695IleGln: 0.695 ± 0.382
5.559IleArg: 5.559 ± 1.63
2.78IleSer: 2.78 ± 0.102
0.0IleThr: 0.0 ± 0.0
1.39IleVal: 1.39 ± 0.764
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.695LysAla: 0.695 ± 0.382
0.0LysCys: 0.0 ± 0.0
2.78LysAsp: 2.78 ± 0.102
4.864LysGlu: 4.864 ± 0.178
2.78LysPhe: 2.78 ± 0.102
4.864LysGly: 4.864 ± 0.178
0.0LysHis: 0.0 ± 0.0
2.78LysIle: 2.78 ± 0.102
9.034LysLys: 9.034 ± 2.164
2.78LysLeu: 2.78 ± 1.528
4.17LysMet: 4.17 ± 0.56
2.78LysAsn: 2.78 ± 0.102
0.695LysPro: 0.695 ± 0.382
2.085LysGln: 2.085 ± 0.28
2.78LysArg: 2.78 ± 1.324
2.085LysSer: 2.085 ± 0.28
1.39LysThr: 1.39 ± 0.662
5.559LysVal: 5.559 ± 1.222
0.0LysTrp: 0.0 ± 0.0
4.864LysTyr: 4.864 ± 0.178
0.0LysXaa: 0.0 ± 0.0
Leu
4.864LeuAla: 4.864 ± 1.604
1.39LeuCys: 1.39 ± 0.764
5.559LeuAsp: 5.559 ± 3.056
11.814LeuGlu: 11.814 ± 0.636
4.864LeuPhe: 4.864 ± 0.178
4.17LeuGly: 4.17 ± 0.866
2.78LeuHis: 2.78 ± 1.324
0.695LeuIle: 0.695 ± 0.382
9.034LeuLys: 9.034 ± 0.738
15.288LeuLeu: 15.288 ± 0.152
2.78LeuMet: 2.78 ± 1.019
2.78LeuAsn: 2.78 ± 1.528
4.864LeuPro: 4.864 ± 1.248
1.39LeuGln: 1.39 ± 0.764
9.034LeuArg: 9.034 ± 2.114
5.559LeuSer: 5.559 ± 1.63
5.559LeuThr: 5.559 ± 1.222
4.864LeuVal: 4.864 ± 0.178
2.085LeuTrp: 2.085 ± 1.146
2.085LeuTyr: 2.085 ± 1.146
0.0LeuXaa: 0.0 ± 0.0
Met
1.39MetAla: 1.39 ± 0.764
0.695MetCys: 0.695 ± 0.382
4.17MetAsp: 4.17 ± 0.56
1.39MetGlu: 1.39 ± 0.764
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.695MetHis: 0.695 ± 0.382
0.0MetIle: 0.0 ± 0.0
2.085MetLys: 2.085 ± 0.28
1.39MetLeu: 1.39 ± 0.662
0.695MetMet: 0.695 ± 0.382
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.695MetGln: 0.695 ± 0.382
3.475MetArg: 3.475 ± 1.91
2.085MetSer: 2.085 ± 0.28
2.085MetThr: 2.085 ± 0.28
2.085MetVal: 2.085 ± 1.146
0.695MetTrp: 0.695 ± 0.382
2.085MetTyr: 2.085 ± 0.28
0.0MetXaa: 0.0 ± 0.0
Asn
2.085AsnAla: 2.085 ± 0.28
0.0AsnCys: 0.0 ± 0.0
2.085AsnAsp: 2.085 ± 0.28
2.085AsnGlu: 2.085 ± 0.28
2.78AsnPhe: 2.78 ± 0.102
0.695AsnGly: 0.695 ± 0.382
1.39AsnHis: 1.39 ± 0.764
0.695AsnIle: 0.695 ± 0.382
2.085AsnLys: 2.085 ± 1.706
1.39AsnLeu: 1.39 ± 0.764
0.0AsnMet: 0.0 ± 0.0
1.39AsnAsn: 1.39 ± 0.764
2.085AsnPro: 2.085 ± 0.28
2.78AsnGln: 2.78 ± 0.102
0.695AsnArg: 0.695 ± 0.382
0.695AsnSer: 0.695 ± 0.382
1.39AsnThr: 1.39 ± 0.662
0.695AsnVal: 0.695 ± 0.382
1.39AsnTrp: 1.39 ± 0.764
2.085AsnTyr: 2.085 ± 0.28
0.0AsnXaa: 0.0 ± 0.0
Pro
7.644ProAla: 7.644 ± 7.205
0.695ProCys: 0.695 ± 0.382
3.475ProAsp: 3.475 ± 0.942
2.78ProGlu: 2.78 ± 1.528
2.085ProPhe: 2.085 ± 1.146
4.864ProGly: 4.864 ± 1.248
2.085ProHis: 2.085 ± 1.146
2.085ProIle: 2.085 ± 1.146
2.085ProLys: 2.085 ± 0.28
2.78ProLeu: 2.78 ± 1.324
1.39ProMet: 1.39 ± 0.764
0.0ProAsn: 0.0 ± 0.0
3.475ProPro: 3.475 ± 2.368
1.39ProGln: 1.39 ± 0.662
4.17ProArg: 4.17 ± 1.986
3.475ProSer: 3.475 ± 0.484
0.695ProThr: 0.695 ± 0.382
2.085ProVal: 2.085 ± 1.146
1.39ProTrp: 1.39 ± 0.764
1.39ProTyr: 1.39 ± 0.764
0.0ProXaa: 0.0 ± 0.0
Gln
4.17GlnAla: 4.17 ± 0.866
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
4.864GlnGlu: 4.864 ± 1.604
2.085GlnPhe: 2.085 ± 1.146
2.78GlnGly: 2.78 ± 0.102
0.695GlnHis: 0.695 ± 1.044
4.17GlnIle: 4.17 ± 1.986
2.085GlnLys: 2.085 ± 0.28
2.78GlnLeu: 2.78 ± 0.102
0.0GlnMet: 0.0 ± 0.0
2.085GlnAsn: 2.085 ± 0.28
2.78GlnPro: 2.78 ± 2.75
2.78GlnGln: 2.78 ± 0.102
2.085GlnArg: 2.085 ± 0.28
0.695GlnSer: 0.695 ± 0.382
0.695GlnThr: 0.695 ± 1.044
3.475GlnVal: 3.475 ± 0.484
0.695GlnTrp: 0.695 ± 0.382
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
10.424ArgAla: 10.424 ± 2.825
1.39ArgCys: 1.39 ± 0.662
2.78ArgAsp: 2.78 ± 1.528
8.339ArgGlu: 8.339 ± 0.306
1.39ArgPhe: 1.39 ± 0.662
5.559ArgGly: 5.559 ± 1.63
0.0ArgHis: 0.0 ± 0.0
2.085ArgIle: 2.085 ± 1.146
2.78ArgLys: 2.78 ± 0.102
9.729ArgLeu: 9.729 ± 1.07
2.085ArgMet: 2.085 ± 1.146
1.39ArgAsn: 1.39 ± 0.662
6.949ArgPro: 6.949 ± 2.394
2.78ArgGln: 2.78 ± 4.175
6.254ArgArg: 6.254 ± 2.012
3.475ArgSer: 3.475 ± 0.484
5.559ArgThr: 5.559 ± 1.222
5.559ArgVal: 5.559 ± 1.222
1.39ArgTrp: 1.39 ± 0.764
2.78ArgTyr: 2.78 ± 0.102
0.0ArgXaa: 0.0 ± 0.0
Ser
2.085SerAla: 2.085 ± 0.28
0.695SerCys: 0.695 ± 0.382
2.085SerAsp: 2.085 ± 1.146
4.17SerGlu: 4.17 ± 0.56
1.39SerPhe: 1.39 ± 0.662
2.78SerGly: 2.78 ± 0.102
2.085SerHis: 2.085 ± 1.146
0.695SerIle: 0.695 ± 0.382
3.475SerLys: 3.475 ± 1.91
5.559SerLeu: 5.559 ± 1.63
1.39SerMet: 1.39 ± 0.662
3.475SerAsn: 3.475 ± 0.942
2.78SerPro: 2.78 ± 1.324
0.695SerGln: 0.695 ± 0.382
7.644SerArg: 7.644 ± 1.502
5.559SerSer: 5.559 ± 1.63
0.0SerThr: 0.0 ± 0.0
1.39SerVal: 1.39 ± 0.662
0.695SerTrp: 0.695 ± 0.382
1.39SerTyr: 1.39 ± 0.662
0.0SerXaa: 0.0 ± 0.0
Thr
6.254ThrAla: 6.254 ± 0.84
0.0ThrCys: 0.0 ± 0.0
0.695ThrAsp: 0.695 ± 0.382
0.0ThrGlu: 0.0 ± 0.0
0.695ThrPhe: 0.695 ± 0.382
8.339ThrGly: 8.339 ± 1.12
0.0ThrHis: 0.0 ± 0.0
0.695ThrIle: 0.695 ± 0.382
3.475ThrLys: 3.475 ± 0.942
4.864ThrLeu: 4.864 ± 0.178
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
2.085ThrPro: 2.085 ± 0.28
0.0ThrGln: 0.0 ± 0.0
2.78ThrArg: 2.78 ± 1.324
2.78ThrSer: 2.78 ± 0.102
2.78ThrThr: 2.78 ± 1.324
0.0ThrVal: 0.0 ± 0.0
0.695ThrTrp: 0.695 ± 0.382
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.949ValAla: 6.949 ± 1.884
0.695ValCys: 0.695 ± 0.382
0.695ValAsp: 0.695 ± 0.382
4.864ValGlu: 4.864 ± 1.604
1.39ValPhe: 1.39 ± 0.662
2.085ValGly: 2.085 ± 0.28
1.39ValHis: 1.39 ± 0.662
7.644ValIle: 7.644 ± 2.776
3.475ValLys: 3.475 ± 0.942
7.644ValLeu: 7.644 ± 0.076
2.085ValMet: 2.085 ± 1.146
2.78ValAsn: 2.78 ± 1.528
2.78ValPro: 2.78 ± 0.102
1.39ValGln: 1.39 ± 0.764
1.39ValArg: 1.39 ± 0.662
2.085ValSer: 2.085 ± 0.28
4.17ValThr: 4.17 ± 0.866
5.559ValVal: 5.559 ± 0.204
0.695ValTrp: 0.695 ± 0.382
0.695ValTyr: 0.695 ± 0.382
0.0ValXaa: 0.0 ± 0.0
Trp
0.695TrpAla: 0.695 ± 0.382
0.695TrpCys: 0.695 ± 0.382
0.0TrpAsp: 0.0 ± 0.0
3.475TrpGlu: 3.475 ± 0.484
0.695TrpPhe: 0.695 ± 0.382
0.695TrpGly: 0.695 ± 0.382
0.0TrpHis: 0.0 ± 0.0
0.695TrpIle: 0.695 ± 0.382
0.0TrpLys: 0.0 ± 0.0
3.475TrpLeu: 3.475 ± 1.91
0.695TrpMet: 0.695 ± 0.382
1.39TrpAsn: 1.39 ± 0.764
0.695TrpPro: 0.695 ± 0.382
0.695TrpGln: 0.695 ± 0.382
1.39TrpArg: 1.39 ± 0.764
0.0TrpSer: 0.0 ± 0.0
0.695TrpThr: 0.695 ± 0.382
0.695TrpVal: 0.695 ± 0.382
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.475TyrAla: 3.475 ± 0.942
2.78TyrCys: 2.78 ± 1.324
4.864TyrAsp: 4.864 ± 1.604
0.695TyrGlu: 0.695 ± 0.382
0.695TyrPhe: 0.695 ± 0.382
2.78TyrGly: 2.78 ± 1.528
0.0TyrHis: 0.0 ± 0.0
0.695TyrIle: 0.695 ± 0.382
0.695TyrLys: 0.695 ± 0.382
3.475TyrLeu: 3.475 ± 0.484
0.0TyrMet: 0.0 ± 0.0
0.695TyrAsn: 0.695 ± 0.382
0.0TyrPro: 0.0 ± 0.0
3.475TyrGln: 3.475 ± 0.942
2.085TyrArg: 2.085 ± 0.28
1.39TyrSer: 1.39 ± 0.662
0.695TyrThr: 0.695 ± 0.382
1.39TyrVal: 1.39 ± 0.764
0.695TyrTrp: 0.695 ± 0.382
2.085TyrTyr: 2.085 ± 0.28
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1440 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski