Amino acid dipepetide frequency for Leucothrix pacifica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.702AlaAla: 8.702 ± 0.111
0.939AlaCys: 0.939 ± 0.03
5.373AlaAsp: 5.373 ± 0.061
5.957AlaGlu: 5.957 ± 0.081
3.257AlaPhe: 3.257 ± 0.043
6.539AlaGly: 6.539 ± 0.086
1.727AlaHis: 1.727 ± 0.036
5.509AlaIle: 5.509 ± 0.065
4.64AlaLys: 4.64 ± 0.062
9.337AlaLeu: 9.337 ± 0.089
2.773AlaMet: 2.773 ± 0.047
3.395AlaAsn: 3.395 ± 0.048
3.077AlaPro: 3.077 ± 0.067
3.435AlaGln: 3.435 ± 0.049
3.921AlaArg: 3.921 ± 0.055
5.667AlaSer: 5.667 ± 0.066
4.559AlaThr: 4.559 ± 0.075
6.058AlaVal: 6.058 ± 0.075
1.051AlaTrp: 1.051 ± 0.029
2.516AlaTyr: 2.516 ± 0.04
0.0AlaXaa: 0.0 ± 0.0
Cys
0.705CysAla: 0.705 ± 0.023
0.136CysCys: 0.136 ± 0.01
0.607CysAsp: 0.607 ± 0.02
0.586CysGlu: 0.586 ± 0.032
0.414CysPhe: 0.414 ± 0.018
0.887CysGly: 0.887 ± 0.029
0.313CysHis: 0.313 ± 0.016
0.553CysIle: 0.553 ± 0.019
0.382CysLys: 0.382 ± 0.018
0.893CysLeu: 0.893 ± 0.028
0.214CysMet: 0.214 ± 0.013
0.347CysAsn: 0.347 ± 0.016
0.493CysPro: 0.493 ± 0.038
0.399CysGln: 0.399 ± 0.017
0.464CysArg: 0.464 ± 0.018
0.65CysSer: 0.65 ± 0.026
0.492CysThr: 0.492 ± 0.022
0.618CysVal: 0.618 ± 0.023
0.12CysTrp: 0.12 ± 0.01
0.302CysTyr: 0.302 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
5.115AspAla: 5.115 ± 0.074
0.566AspCys: 0.566 ± 0.02
3.641AspAsp: 3.641 ± 0.073
4.322AspGlu: 4.322 ± 0.063
2.554AspPhe: 2.554 ± 0.049
4.237AspGly: 4.237 ± 0.082
1.252AspHis: 1.252 ± 0.031
3.922AspIle: 3.922 ± 0.052
3.135AspLys: 3.135 ± 0.055
5.546AspLeu: 5.546 ± 0.066
1.507AspMet: 1.507 ± 0.032
2.403AspAsn: 2.403 ± 0.049
2.361AspPro: 2.361 ± 0.044
2.257AspGln: 2.257 ± 0.044
2.616AspArg: 2.616 ± 0.044
3.64AspSer: 3.64 ± 0.068
3.211AspThr: 3.211 ± 0.052
3.918AspVal: 3.918 ± 0.058
0.975AspTrp: 0.975 ± 0.029
2.31AspTyr: 2.31 ± 0.044
0.0AspXaa: 0.0 ± 0.0
Glu
6.058GluAla: 6.058 ± 0.079
0.487GluCys: 0.487 ± 0.018
3.154GluAsp: 3.154 ± 0.051
3.688GluGlu: 3.688 ± 0.068
2.265GluPhe: 2.265 ± 0.044
3.778GluGly: 3.778 ± 0.065
1.491GluHis: 1.491 ± 0.033
3.892GluIle: 3.892 ± 0.056
3.648GluLys: 3.648 ± 0.06
6.508GluLeu: 6.508 ± 0.073
1.641GluMet: 1.641 ± 0.036
2.488GluAsn: 2.488 ± 0.046
2.145GluPro: 2.145 ± 0.042
3.363GluGln: 3.363 ± 0.051
3.503GluArg: 3.503 ± 0.058
4.021GluSer: 4.021 ± 0.052
3.461GluThr: 3.461 ± 0.049
4.436GluVal: 4.436 ± 0.056
0.831GluTrp: 0.831 ± 0.024
1.877GluTyr: 1.877 ± 0.038
0.0GluXaa: 0.0 ± 0.0
Phe
3.265PheAla: 3.265 ± 0.045
0.422PheCys: 0.422 ± 0.018
2.706PheAsp: 2.706 ± 0.047
2.487PheGlu: 2.487 ± 0.039
1.599PhePhe: 1.599 ± 0.038
2.988PheGly: 2.988 ± 0.051
0.783PheHis: 0.783 ± 0.027
2.442PheIle: 2.442 ± 0.043
1.959PheLys: 1.959 ± 0.035
3.495PheLeu: 3.495 ± 0.056
1.011PheMet: 1.011 ± 0.028
1.675PheAsn: 1.675 ± 0.033
1.505PhePro: 1.505 ± 0.029
1.277PheGln: 1.277 ± 0.034
1.722PheArg: 1.722 ± 0.039
3.063PheSer: 3.063 ± 0.05
2.249PheThr: 2.249 ± 0.046
2.522PheVal: 2.522 ± 0.039
0.598PheTrp: 0.598 ± 0.02
1.375PheTyr: 1.375 ± 0.033
0.0PheXaa: 0.0 ± 0.0
Gly
5.454GlyAla: 5.454 ± 0.077
0.813GlyCys: 0.813 ± 0.043
4.001GlyAsp: 4.001 ± 0.058
4.331GlyGlu: 4.331 ± 0.054
3.187GlyPhe: 3.187 ± 0.052
5.205GlyGly: 5.205 ± 0.094
1.592GlyHis: 1.592 ± 0.034
4.627GlyIle: 4.627 ± 0.058
4.057GlyLys: 4.057 ± 0.058
7.135GlyLeu: 7.135 ± 0.077
2.184GlyMet: 2.184 ± 0.042
2.713GlyAsn: 2.713 ± 0.058
1.769GlyPro: 1.769 ± 0.037
2.657GlyGln: 2.657 ± 0.04
3.318GlyArg: 3.318 ± 0.052
4.607GlySer: 4.607 ± 0.067
3.638GlyThr: 3.638 ± 0.056
5.404GlyVal: 5.404 ± 0.07
0.961GlyTrp: 0.961 ± 0.025
2.437GlyTyr: 2.437 ± 0.04
0.0GlyXaa: 0.0 ± 0.0
His
1.705HisAla: 1.705 ± 0.031
0.3HisCys: 0.3 ± 0.013
1.316HisAsp: 1.316 ± 0.033
1.27HisGlu: 1.27 ± 0.031
0.998HisPhe: 0.998 ± 0.026
1.591HisGly: 1.591 ± 0.034
0.687HisHis: 0.687 ± 0.021
1.327HisIle: 1.327 ± 0.03
1.004HisLys: 1.004 ± 0.026
2.209HisLeu: 2.209 ± 0.04
0.533HisMet: 0.533 ± 0.018
0.883HisAsn: 0.883 ± 0.024
1.168HisPro: 1.168 ± 0.031
1.046HisGln: 1.046 ± 0.031
1.131HisArg: 1.131 ± 0.031
1.471HisSer: 1.471 ± 0.032
1.075HisThr: 1.075 ± 0.028
1.251HisVal: 1.251 ± 0.032
0.391HisTrp: 0.391 ± 0.019
0.884HisTyr: 0.884 ± 0.029
0.0HisXaa: 0.0 ± 0.0
Ile
6.103IleAla: 6.103 ± 0.072
0.624IleCys: 0.624 ± 0.023
4.087IleAsp: 4.087 ± 0.059
4.17IleGlu: 4.17 ± 0.062
2.027IlePhe: 2.027 ± 0.04
4.43IleGly: 4.43 ± 0.063
1.291IleHis: 1.291 ± 0.034
3.558IleIle: 3.558 ± 0.061
3.151IleLys: 3.151 ± 0.053
5.222IleLeu: 5.222 ± 0.075
1.295IleMet: 1.295 ± 0.034
2.786IleAsn: 2.786 ± 0.051
2.926IlePro: 2.926 ± 0.052
2.239IleGln: 2.239 ± 0.04
3.078IleArg: 3.078 ± 0.05
4.385IleSer: 4.385 ± 0.061
3.546IleThr: 3.546 ± 0.05
3.826IleVal: 3.826 ± 0.059
0.631IleTrp: 0.631 ± 0.022
1.617IleTyr: 1.617 ± 0.036
0.0IleXaa: 0.0 ± 0.0
Lys
4.834LysAla: 4.834 ± 0.069
0.287LysCys: 0.287 ± 0.016
2.796LysAsp: 2.796 ± 0.058
2.857LysGlu: 2.857 ± 0.048
1.376LysPhe: 1.376 ± 0.032
3.248LysGly: 3.248 ± 0.053
1.317LysHis: 1.317 ± 0.032
2.799LysIle: 2.799 ± 0.054
2.983LysLys: 2.983 ± 0.059
5.025LysLeu: 5.025 ± 0.064
1.264LysMet: 1.264 ± 0.031
2.112LysAsn: 2.112 ± 0.042
2.647LysPro: 2.647 ± 0.051
2.958LysGln: 2.958 ± 0.053
2.958LysArg: 2.958 ± 0.054
3.308LysSer: 3.308 ± 0.053
3.146LysThr: 3.146 ± 0.053
3.587LysVal: 3.587 ± 0.057
0.53LysTrp: 0.53 ± 0.02
1.425LysTyr: 1.425 ± 0.037
0.001LysXaa: 0.001 ± 0.001
Leu
9.151LeuAla: 9.151 ± 0.099
1.009LeuCys: 1.009 ± 0.026
5.91LeuAsp: 5.91 ± 0.073
6.213LeuGlu: 6.213 ± 0.075
4.101LeuPhe: 4.101 ± 0.062
6.905LeuGly: 6.905 ± 0.088
2.041LeuHis: 2.041 ± 0.037
6.192LeuIle: 6.192 ± 0.078
5.523LeuLys: 5.523 ± 0.063
10.67LeuLeu: 10.67 ± 0.124
2.687LeuMet: 2.687 ± 0.044
4.256LeuAsn: 4.256 ± 0.05
4.657LeuPro: 4.657 ± 0.057
3.883LeuGln: 3.883 ± 0.072
4.898LeuArg: 4.898 ± 0.062
8.085LeuSer: 8.085 ± 0.08
5.571LeuThr: 5.571 ± 0.064
6.388LeuVal: 6.388 ± 0.082
1.156LeuTrp: 1.156 ± 0.032
2.618LeuTyr: 2.618 ± 0.042
0.0LeuXaa: 0.0 ± 0.0
Met
2.388MetAla: 2.388 ± 0.046
0.19MetCys: 0.19 ± 0.012
1.44MetAsp: 1.44 ± 0.037
1.302MetGlu: 1.302 ± 0.031
0.826MetPhe: 0.826 ± 0.024
1.828MetGly: 1.828 ± 0.036
0.543MetHis: 0.543 ± 0.019
1.571MetIle: 1.571 ± 0.036
1.595MetLys: 1.595 ± 0.035
2.634MetLeu: 2.634 ± 0.049
0.813MetMet: 0.813 ± 0.026
1.184MetAsn: 1.184 ± 0.03
1.295MetPro: 1.295 ± 0.03
1.176MetGln: 1.176 ± 0.03
1.316MetArg: 1.316 ± 0.029
2.032MetSer: 2.032 ± 0.037
1.63MetThr: 1.63 ± 0.034
1.763MetVal: 1.763 ± 0.038
0.227MetTrp: 0.227 ± 0.013
0.527MetTyr: 0.527 ± 0.021
0.0MetXaa: 0.0 ± 0.0
Asn
3.4AsnAla: 3.4 ± 0.06
0.39AsnCys: 0.39 ± 0.016
2.481AsnAsp: 2.481 ± 0.054
2.266AsnGlu: 2.266 ± 0.04
1.392AsnPhe: 1.392 ± 0.031
2.938AsnGly: 2.938 ± 0.069
0.992AsnHis: 0.992 ± 0.028
2.656AsnIle: 2.656 ± 0.042
2.04AsnLys: 2.04 ± 0.042
3.713AsnLeu: 3.713 ± 0.051
0.898AsnMet: 0.898 ± 0.026
1.934AsnAsn: 1.934 ± 0.049
2.216AsnPro: 2.216 ± 0.041
1.796AsnGln: 1.796 ± 0.038
2.024AsnArg: 2.024 ± 0.04
2.345AsnSer: 2.345 ± 0.044
2.507AsnThr: 2.507 ± 0.058
2.417AsnVal: 2.417 ± 0.05
0.631AsnTrp: 0.631 ± 0.022
1.383AsnTyr: 1.383 ± 0.032
0.0AsnXaa: 0.0 ± 0.0
Pro
3.708ProAla: 3.708 ± 0.067
0.337ProCys: 0.337 ± 0.016
3.03ProAsp: 3.03 ± 0.049
3.651ProGlu: 3.651 ± 0.057
1.676ProPhe: 1.676 ± 0.031
2.56ProGly: 2.56 ± 0.041
0.876ProHis: 0.876 ± 0.028
2.229ProIle: 2.229 ± 0.038
2.038ProLys: 2.038 ± 0.041
3.99ProLeu: 3.99 ± 0.061
1.076ProMet: 1.076 ± 0.031
1.612ProAsn: 1.612 ± 0.034
1.485ProPro: 1.485 ± 0.04
1.532ProGln: 1.532 ± 0.036
1.616ProArg: 1.616 ± 0.033
2.522ProSer: 2.522 ± 0.047
2.122ProThr: 2.122 ± 0.043
3.409ProVal: 3.409 ± 0.055
0.568ProTrp: 0.568 ± 0.021
1.304ProTyr: 1.304 ± 0.032
0.0ProXaa: 0.0 ± 0.0
Gln
4.266GlnAla: 4.266 ± 0.066
0.375GlnCys: 0.375 ± 0.019
1.969GlnAsp: 1.969 ± 0.037
2.193GlnGlu: 2.193 ± 0.044
1.565GlnPhe: 1.565 ± 0.035
2.72GlnGly: 2.72 ± 0.037
1.112GlnHis: 1.112 ± 0.026
2.321GlnIle: 2.321 ± 0.038
1.992GlnLys: 1.992 ± 0.044
4.718GlnLeu: 4.718 ± 0.073
0.992GlnMet: 0.992 ± 0.024
1.482GlnAsn: 1.482 ± 0.031
1.622GlnPro: 1.622 ± 0.03
2.858GlnGln: 2.858 ± 0.066
2.584GlnArg: 2.584 ± 0.048
2.885GlnSer: 2.885 ± 0.048
2.216GlnThr: 2.216 ± 0.039
2.788GlnVal: 2.788 ± 0.044
0.676GlnTrp: 0.676 ± 0.022
1.305GlnTyr: 1.305 ± 0.032
0.0GlnXaa: 0.0 ± 0.0
Arg
3.688ArgAla: 3.688 ± 0.054
0.461ArgCys: 0.461 ± 0.017
2.835ArgAsp: 2.835 ± 0.048
3.301ArgGlu: 3.301 ± 0.053
2.322ArgPhe: 2.322 ± 0.041
3.009ArgGly: 3.009 ± 0.051
1.198ArgHis: 1.198 ± 0.03
3.168ArgIle: 3.168 ± 0.05
2.5ArgLys: 2.5 ± 0.039
5.449ArgLeu: 5.449 ± 0.074
1.353ArgMet: 1.353 ± 0.028
1.95ArgAsn: 1.95 ± 0.038
1.801ArgPro: 1.801 ± 0.039
2.28ArgGln: 2.28 ± 0.052
2.649ArgArg: 2.649 ± 0.051
2.937ArgSer: 2.937 ± 0.044
2.328ArgThr: 2.328 ± 0.041
3.356ArgVal: 3.356 ± 0.05
0.759ArgTrp: 0.759 ± 0.026
1.826ArgTyr: 1.826 ± 0.035
0.0ArgXaa: 0.0 ± 0.0
Ser
5.655SerAla: 5.655 ± 0.068
0.619SerCys: 0.619 ± 0.022
4.133SerAsp: 4.133 ± 0.064
3.983SerGlu: 3.983 ± 0.053
2.783SerPhe: 2.783 ± 0.046
5.621SerGly: 5.621 ± 0.082
1.516SerHis: 1.516 ± 0.034
3.984SerIle: 3.984 ± 0.057
3.181SerLys: 3.181 ± 0.051
7.14SerLeu: 7.14 ± 0.086
1.856SerMet: 1.856 ± 0.038
2.681SerAsn: 2.681 ± 0.047
2.666SerPro: 2.666 ± 0.045
2.642SerGln: 2.642 ± 0.039
3.348SerArg: 3.348 ± 0.043
4.383SerSer: 4.383 ± 0.078
3.551SerThr: 3.551 ± 0.053
4.725SerVal: 4.725 ± 0.066
0.865SerTrp: 0.865 ± 0.025
2.047SerTyr: 2.047 ± 0.044
0.0SerXaa: 0.0 ± 0.0
Thr
4.838ThrAla: 4.838 ± 0.071
0.442ThrCys: 0.442 ± 0.018
3.297ThrAsp: 3.297 ± 0.06
3.385ThrGlu: 3.385 ± 0.05
1.946ThrPhe: 1.946 ± 0.036
4.276ThrGly: 4.276 ± 0.064
1.232ThrHis: 1.232 ± 0.029
3.341ThrIle: 3.341 ± 0.053
2.259ThrLys: 2.259 ± 0.039
6.165ThrLeu: 6.165 ± 0.067
1.204ThrMet: 1.204 ± 0.029
2.034ThrAsn: 2.034 ± 0.045
2.964ThrPro: 2.964 ± 0.051
2.325ThrGln: 2.325 ± 0.045
2.412ThrArg: 2.412 ± 0.038
3.435ThrSer: 3.435 ± 0.054
3.169ThrThr: 3.169 ± 0.061
3.944ThrVal: 3.944 ± 0.065
0.583ThrTrp: 0.583 ± 0.02
1.507ThrTyr: 1.507 ± 0.035
0.0ThrXaa: 0.0 ± 0.0
Val
6.126ValAla: 6.126 ± 0.079
0.689ValCys: 0.689 ± 0.024
4.159ValAsp: 4.159 ± 0.057
4.317ValGlu: 4.317 ± 0.057
2.833ValPhe: 2.833 ± 0.048
4.389ValGly: 4.389 ± 0.066
1.211ValHis: 1.211 ± 0.031
4.571ValIle: 4.571 ± 0.055
3.388ValLys: 3.388 ± 0.054
6.964ValLeu: 6.964 ± 0.084
1.97ValMet: 1.97 ± 0.039
2.865ValAsn: 2.865 ± 0.055
2.671ValPro: 2.671 ± 0.046
2.049ValGln: 2.049 ± 0.037
3.082ValArg: 3.082 ± 0.049
5.076ValSer: 5.076 ± 0.064
4.078ValThr: 4.078 ± 0.062
5.14ValVal: 5.14 ± 0.071
0.786ValTrp: 0.786 ± 0.023
1.905ValTyr: 1.905 ± 0.042
0.0ValXaa: 0.0 ± 0.0
Trp
0.873TrpAla: 0.873 ± 0.026
0.138TrpCys: 0.138 ± 0.01
0.698TrpAsp: 0.698 ± 0.022
0.678TrpGlu: 0.678 ± 0.025
0.593TrpPhe: 0.593 ± 0.023
0.814TrpGly: 0.814 ± 0.026
0.344TrpHis: 0.344 ± 0.014
0.734TrpIle: 0.734 ± 0.021
0.617TrpLys: 0.617 ± 0.024
1.678TrpLeu: 1.678 ± 0.044
0.385TrpMet: 0.385 ± 0.017
0.528TrpAsn: 0.528 ± 0.023
0.487TrpPro: 0.487 ± 0.019
0.763TrpGln: 0.763 ± 0.029
0.706TrpArg: 0.706 ± 0.025
0.85TrpSer: 0.85 ± 0.026
0.554TrpThr: 0.554 ± 0.022
0.932TrpVal: 0.932 ± 0.026
0.199TrpTrp: 0.199 ± 0.013
0.446TrpTyr: 0.446 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.399TyrAla: 2.399 ± 0.04
0.353TyrCys: 0.353 ± 0.016
1.853TyrAsp: 1.853 ± 0.043
1.777TyrGlu: 1.777 ± 0.031
1.429TyrPhe: 1.429 ± 0.036
2.125TyrGly: 2.125 ± 0.041
0.725TyrHis: 0.725 ± 0.026
1.595TyrIle: 1.595 ± 0.037
1.365TyrLys: 1.365 ± 0.033
3.422TyrLeu: 3.422 ± 0.057
0.623TyrMet: 0.623 ± 0.019
1.091TyrAsn: 1.091 ± 0.031
1.387TyrPro: 1.387 ± 0.028
1.705TyrGln: 1.705 ± 0.035
1.825TyrArg: 1.825 ± 0.038
2.015TyrSer: 2.015 ± 0.04
1.654TyrThr: 1.654 ± 0.04
1.786TyrVal: 1.786 ± 0.039
0.481TyrTrp: 0.481 ± 0.019
1.056TyrTyr: 1.056 ± 0.032
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.001XaaGlu: 0.001 ± 0.001
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4538 proteins (1465375 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski