Amino acid dipepetide frequency for Howler monkey associated porprismacovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.562AlaAla: 1.562 ± 0.852
0.0AlaCys: 0.0 ± 0.0
4.688AlaAsp: 4.688 ± 2.555
3.125AlaGlu: 3.125 ± 0.661
1.562AlaPhe: 1.562 ± 0.852
7.812AlaGly: 7.812 ± 4.258
0.0AlaHis: 0.0 ± 0.0
4.688AlaIle: 4.688 ± 2.174
1.562AlaLys: 1.562 ± 1.513
10.938AlaLeu: 10.938 ± 1.232
4.688AlaMet: 4.688 ± 0.616
4.688AlaAsn: 4.688 ± 2.555
1.562AlaPro: 1.562 ± 0.852
3.125AlaGln: 3.125 ± 1.703
1.562AlaArg: 1.562 ± 0.852
12.5AlaSer: 12.5 ± 0.281
6.25AlaThr: 6.25 ± 1.042
3.125AlaVal: 3.125 ± 1.703
0.0AlaTrp: 0.0 ± 0.0
4.688AlaTyr: 4.688 ± 0.19
0.0AlaXaa: 0.0 ± 0.0
Cys
1.562CysAla: 1.562 ± 1.513
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
3.125CysLys: 3.125 ± 3.026
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.125AspAla: 3.125 ± 1.703
1.562AspCys: 1.562 ± 1.513
1.562AspAsp: 1.562 ± 0.852
1.562AspGlu: 1.562 ± 1.513
4.688AspPhe: 4.688 ± 2.555
1.562AspGly: 1.562 ± 1.513
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
4.688AspLys: 4.688 ± 4.539
3.125AspLeu: 3.125 ± 0.661
3.125AspMet: 3.125 ± 1.703
6.25AspAsn: 6.25 ± 1.042
4.688AspPro: 4.688 ± 2.555
1.562AspGln: 1.562 ± 0.852
4.688AspArg: 4.688 ± 4.539
3.125AspSer: 3.125 ± 0.661
1.562AspThr: 1.562 ± 0.852
3.125AspVal: 3.125 ± 1.703
1.562AspTrp: 1.562 ± 1.513
3.125AspTyr: 3.125 ± 0.661
0.0AspXaa: 0.0 ± 0.0
Glu
4.688GluAla: 4.688 ± 0.19
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
3.125GluGlu: 3.125 ± 0.661
6.25GluPhe: 6.25 ± 1.323
3.125GluGly: 3.125 ± 3.026
0.0GluHis: 0.0 ± 0.0
1.562GluIle: 1.562 ± 0.852
0.0GluLys: 0.0 ± 0.0
1.562GluLeu: 1.562 ± 1.513
1.562GluMet: 1.562 ± 0.852
0.0GluAsn: 0.0 ± 0.0
1.562GluPro: 1.562 ± 0.852
1.562GluGln: 1.562 ± 0.852
1.562GluArg: 1.562 ± 1.513
4.688GluSer: 4.688 ± 0.19
4.688GluThr: 4.688 ± 2.174
6.25GluVal: 6.25 ± 1.323
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.125PheAla: 3.125 ± 1.703
0.0PheCys: 0.0 ± 0.0
1.562PheAsp: 1.562 ± 1.513
1.562PheGlu: 1.562 ± 0.852
3.125PhePhe: 3.125 ± 0.661
4.688PheGly: 4.688 ± 0.19
1.562PheHis: 1.562 ± 0.852
1.562PheIle: 1.562 ± 0.852
4.688PheLys: 4.688 ± 2.555
1.562PheLeu: 1.562 ± 0.852
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.562PhePro: 1.562 ± 0.852
1.562PheGln: 1.562 ± 0.852
6.25PheArg: 6.25 ± 1.042
3.125PheSer: 3.125 ± 1.703
6.25PheThr: 6.25 ± 1.042
1.562PheVal: 1.562 ± 1.513
0.0PheTrp: 0.0 ± 0.0
1.562PheTyr: 1.562 ± 0.852
0.0PheXaa: 0.0 ± 0.0
Gly
7.812GlyAla: 7.812 ± 1.893
0.0GlyCys: 0.0 ± 0.0
3.125GlyAsp: 3.125 ± 1.703
3.125GlyGlu: 3.125 ± 0.661
3.125GlyPhe: 3.125 ± 1.703
3.125GlyGly: 3.125 ± 0.661
0.0GlyHis: 0.0 ± 0.0
3.125GlyIle: 3.125 ± 1.703
4.688GlyLys: 4.688 ± 4.539
6.25GlyLeu: 6.25 ± 1.042
3.125GlyMet: 3.125 ± 1.703
3.125GlyAsn: 3.125 ± 0.661
1.562GlyPro: 1.562 ± 0.852
4.688GlyGln: 4.688 ± 2.174
3.125GlyArg: 3.125 ± 0.661
3.125GlySer: 3.125 ± 1.703
6.25GlyThr: 6.25 ± 3.406
6.25GlyVal: 6.25 ± 1.042
1.562GlyTrp: 1.562 ± 0.852
3.125GlyTyr: 3.125 ± 0.661
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.562HisGlu: 1.562 ± 0.852
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.562HisIle: 1.562 ± 1.513
1.562HisLys: 1.562 ± 0.852
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.562HisArg: 1.562 ± 0.852
0.0HisSer: 0.0 ± 0.0
3.125HisThr: 3.125 ± 1.703
0.0HisVal: 0.0 ± 0.0
1.562HisTrp: 1.562 ± 1.513
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.125IleAla: 3.125 ± 1.703
0.0IleCys: 0.0 ± 0.0
1.562IleAsp: 1.562 ± 0.852
3.125IleGlu: 3.125 ± 0.661
3.125IlePhe: 3.125 ± 1.703
1.562IleGly: 1.562 ± 1.513
1.562IleHis: 1.562 ± 0.852
4.688IleIle: 4.688 ± 2.174
3.125IleLys: 3.125 ± 0.661
4.688IleLeu: 4.688 ± 2.555
1.562IleMet: 1.562 ± 1.513
0.0IleAsn: 0.0 ± 0.0
6.25IlePro: 6.25 ± 1.323
3.125IleGln: 3.125 ± 3.026
4.688IleArg: 4.688 ± 4.539
6.25IleSer: 6.25 ± 3.406
0.0IleThr: 0.0 ± 0.0
3.125IleVal: 3.125 ± 0.661
0.0IleTrp: 0.0 ± 0.0
4.688IleTyr: 4.688 ± 2.555
0.0IleXaa: 0.0 ± 0.0
Lys
6.25LysAla: 6.25 ± 1.042
0.0LysCys: 0.0 ± 0.0
1.562LysAsp: 1.562 ± 1.513
3.125LysGlu: 3.125 ± 3.026
3.125LysPhe: 3.125 ± 1.703
1.562LysGly: 1.562 ± 0.852
4.688LysHis: 4.688 ± 2.174
3.125LysIle: 3.125 ± 0.661
4.688LysLys: 4.688 ± 2.174
1.562LysLeu: 1.562 ± 1.513
1.562LysMet: 1.562 ± 1.513
3.125LysAsn: 3.125 ± 3.026
1.562LysPro: 1.562 ± 1.513
0.0LysGln: 0.0 ± 0.0
4.688LysArg: 4.688 ± 2.174
3.125LysSer: 3.125 ± 0.661
1.562LysThr: 1.562 ± 0.852
1.562LysVal: 1.562 ± 1.513
3.125LysTrp: 3.125 ± 3.026
1.562LysTyr: 1.562 ± 0.852
0.0LysXaa: 0.0 ± 0.0
Leu
1.562LeuAla: 1.562 ± 0.852
0.0LeuCys: 0.0 ± 0.0
4.688LeuAsp: 4.688 ± 2.174
3.125LeuGlu: 3.125 ± 0.661
4.688LeuPhe: 4.688 ± 2.555
4.688LeuGly: 4.688 ± 2.555
0.0LeuHis: 0.0 ± 0.0
4.688LeuIle: 4.688 ± 0.19
1.562LeuLys: 1.562 ± 0.852
1.562LeuLeu: 1.562 ± 0.852
0.0LeuMet: 0.0 ± 0.934
1.562LeuAsn: 1.562 ± 0.852
6.25LeuPro: 6.25 ± 3.406
1.562LeuGln: 1.562 ± 0.852
4.688LeuArg: 4.688 ± 2.174
3.125LeuSer: 3.125 ± 0.661
6.25LeuThr: 6.25 ± 1.042
6.25LeuVal: 6.25 ± 1.323
4.688LeuTrp: 4.688 ± 0.19
1.562LeuTyr: 1.562 ± 1.513
0.0LeuXaa: 0.0 ± 0.0
Met
1.562MetAla: 1.562 ± 0.852
0.0MetCys: 0.0 ± 0.0
1.562MetAsp: 1.562 ± 0.852
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
3.125MetGly: 3.125 ± 1.703
0.0MetHis: 0.0 ± 0.0
1.562MetIle: 1.562 ± 0.852
0.0MetLys: 0.0 ± 0.0
6.25MetLeu: 6.25 ± 1.323
3.125MetMet: 3.125 ± 1.703
0.0MetAsn: 0.0 ± 0.0
1.562MetPro: 1.562 ± 0.852
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
4.688MetSer: 4.688 ± 2.174
3.125MetThr: 3.125 ± 0.661
9.375MetVal: 9.375 ± 1.984
0.0MetTrp: 0.0 ± 0.0
4.688MetTyr: 4.688 ± 0.19
0.0MetXaa: 0.0 ± 0.0
Asn
1.562AsnAla: 1.562 ± 0.852
0.0AsnCys: 0.0 ± 0.0
3.125AsnAsp: 3.125 ± 3.026
1.562AsnGlu: 1.562 ± 1.513
0.0AsnPhe: 0.0 ± 0.0
6.25AsnGly: 6.25 ± 1.042
0.0AsnHis: 0.0 ± 0.0
4.688AsnIle: 4.688 ± 0.19
3.125AsnLys: 3.125 ± 0.661
3.125AsnLeu: 3.125 ± 0.661
1.562AsnMet: 1.562 ± 0.852
4.688AsnAsn: 4.688 ± 0.19
3.125AsnPro: 3.125 ± 1.703
4.688AsnGln: 4.688 ± 0.19
1.562AsnArg: 1.562 ± 0.852
4.688AsnSer: 4.688 ± 2.555
3.125AsnThr: 3.125 ± 1.703
6.25AsnVal: 6.25 ± 1.042
0.0AsnTrp: 0.0 ± 0.0
1.562AsnTyr: 1.562 ± 0.852
0.0AsnXaa: 0.0 ± 0.0
Pro
10.938ProAla: 10.938 ± 5.961
0.0ProCys: 0.0 ± 0.0
4.688ProAsp: 4.688 ± 0.19
0.0ProGlu: 0.0 ± 0.0
0.0ProPhe: 0.0 ± 0.0
0.0ProGly: 0.0 ± 0.0
0.0ProHis: 0.0 ± 0.0
3.125ProIle: 3.125 ± 1.703
3.125ProLys: 3.125 ± 0.661
6.25ProLeu: 6.25 ± 3.406
3.125ProMet: 3.125 ± 1.703
3.125ProAsn: 3.125 ± 0.661
4.688ProPro: 4.688 ± 0.19
1.562ProGln: 1.562 ± 0.852
3.125ProArg: 3.125 ± 0.661
3.125ProSer: 3.125 ± 1.703
9.375ProThr: 9.375 ± 0.381
1.562ProVal: 1.562 ± 0.852
1.562ProTrp: 1.562 ± 0.852
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
6.25GlnAla: 6.25 ± 3.687
0.0GlnCys: 0.0 ± 0.0
1.562GlnAsp: 1.562 ± 0.852
1.562GlnGlu: 1.562 ± 0.852
4.688GlnPhe: 4.688 ± 0.19
3.125GlnGly: 3.125 ± 0.661
0.0GlnHis: 0.0 ± 0.0
4.688GlnIle: 4.688 ± 0.19
1.562GlnLys: 1.562 ± 1.513
1.562GlnLeu: 1.562 ± 0.852
1.562GlnMet: 1.562 ± 1.513
3.125GlnAsn: 3.125 ± 1.703
3.125GlnPro: 3.125 ± 1.703
0.0GlnGln: 0.0 ± 0.0
3.125GlnArg: 3.125 ± 0.661
0.0GlnSer: 0.0 ± 0.0
3.125GlnThr: 3.125 ± 1.703
0.0GlnVal: 0.0 ± 0.0
1.562GlnTrp: 1.562 ± 1.513
1.562GlnTyr: 1.562 ± 1.513
0.0GlnXaa: 0.0 ± 0.0
Arg
4.688ArgAla: 4.688 ± 2.174
0.0ArgCys: 0.0 ± 0.0
3.125ArgAsp: 3.125 ± 0.661
3.125ArgGlu: 3.125 ± 3.026
3.125ArgPhe: 3.125 ± 0.661
4.688ArgGly: 4.688 ± 2.174
0.0ArgHis: 0.0 ± 0.0
3.125ArgIle: 3.125 ± 0.661
3.125ArgLys: 3.125 ± 0.661
3.125ArgLeu: 3.125 ± 0.661
6.25ArgMet: 6.25 ± 1.323
3.125ArgAsn: 3.125 ± 1.703
3.125ArgPro: 3.125 ± 0.661
1.562ArgGln: 1.562 ± 1.513
1.562ArgArg: 1.562 ± 0.852
0.0ArgSer: 0.0 ± 0.0
1.562ArgThr: 1.562 ± 1.513
0.0ArgVal: 0.0 ± 0.0
1.562ArgTrp: 1.562 ± 1.513
1.562ArgTyr: 1.562 ± 1.513
0.0ArgXaa: 0.0 ± 0.0
Ser
3.125SerAla: 3.125 ± 1.703
0.0SerCys: 0.0 ± 0.0
4.688SerAsp: 4.688 ± 0.19
3.125SerGlu: 3.125 ± 1.703
1.562SerPhe: 1.562 ± 0.852
4.688SerGly: 4.688 ± 2.555
1.562SerHis: 1.562 ± 0.852
6.25SerIle: 6.25 ± 1.323
1.562SerLys: 1.562 ± 1.513
4.688SerLeu: 4.688 ± 0.19
1.562SerMet: 1.562 ± 0.852
6.25SerAsn: 6.25 ± 1.042
6.25SerPro: 6.25 ± 3.406
1.562SerGln: 1.562 ± 1.513
3.125SerArg: 3.125 ± 3.026
1.562SerSer: 1.562 ± 1.513
7.812SerThr: 7.812 ± 2.836
3.125SerVal: 3.125 ± 1.703
3.125SerTrp: 3.125 ± 0.661
4.688SerTyr: 4.688 ± 0.19
0.0SerXaa: 0.0 ± 0.0
Thr
7.812ThrAla: 7.812 ± 0.471
0.0ThrCys: 0.0 ± 0.0
6.25ThrAsp: 6.25 ± 1.042
4.688ThrGlu: 4.688 ± 2.555
1.562ThrPhe: 1.562 ± 0.852
7.812ThrGly: 7.812 ± 0.471
0.0ThrHis: 0.0 ± 0.0
4.688ThrIle: 4.688 ± 0.19
1.562ThrLys: 1.562 ± 1.513
4.688ThrLeu: 4.688 ± 2.555
0.0ThrMet: 0.0 ± 0.0
7.812ThrAsn: 7.812 ± 0.471
6.25ThrPro: 6.25 ± 1.042
4.688ThrGln: 4.688 ± 2.555
1.562ThrArg: 1.562 ± 0.852
7.812ThrSer: 7.812 ± 0.471
7.812ThrThr: 7.812 ± 1.893
6.25ThrVal: 6.25 ± 1.323
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.25ValAla: 6.25 ± 1.042
0.0ValCys: 0.0 ± 0.0
1.562ValAsp: 1.562 ± 0.852
0.0ValGlu: 0.0 ± 0.0
1.562ValPhe: 1.562 ± 0.852
9.375ValGly: 9.375 ± 2.745
1.562ValHis: 1.562 ± 0.852
1.562ValIle: 1.562 ± 0.852
1.562ValLys: 1.562 ± 1.513
3.125ValLeu: 3.125 ± 3.026
3.125ValMet: 3.125 ± 0.661
4.688ValAsn: 4.688 ± 0.19
4.688ValPro: 4.688 ± 0.19
4.688ValGln: 4.688 ± 2.174
0.0ValArg: 0.0 ± 0.0
6.25ValSer: 6.25 ± 1.323
6.25ValThr: 6.25 ± 1.042
1.562ValVal: 1.562 ± 1.513
3.125ValTrp: 3.125 ± 0.661
1.562ValTyr: 1.562 ± 1.513
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.562TrpCys: 1.562 ± 1.513
1.562TrpAsp: 1.562 ± 1.513
1.562TrpGlu: 1.562 ± 1.513
1.562TrpPhe: 1.562 ± 1.513
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.562TrpIle: 1.562 ± 1.513
3.125TrpLys: 3.125 ± 1.703
0.0TrpLeu: 0.0 ± 0.0
1.562TrpMet: 1.562 ± 0.852
1.562TrpAsn: 1.562 ± 0.852
1.562TrpPro: 1.562 ± 0.852
1.562TrpGln: 1.562 ± 1.513
1.562TrpArg: 1.562 ± 1.513
1.562TrpSer: 1.562 ± 1.513
1.562TrpThr: 1.562 ± 1.513
1.562TrpVal: 1.562 ± 0.852
0.0TrpTrp: 0.0 ± 0.0
1.562TrpTyr: 1.562 ± 1.513
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.125TyrAla: 3.125 ± 1.703
1.562TyrCys: 1.562 ± 1.513
7.812TyrAsp: 7.812 ± 2.836
3.125TyrGlu: 3.125 ± 0.661
1.562TyrPhe: 1.562 ± 0.852
3.125TyrGly: 3.125 ± 1.703
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
3.125TyrLys: 3.125 ± 0.661
0.0TyrLeu: 0.0 ± 0.0
1.562TyrMet: 1.562 ± 1.513
1.562TyrAsn: 1.562 ± 0.852
0.0TyrPro: 0.0 ± 0.0
4.688TyrGln: 4.688 ± 0.19
0.0TyrArg: 0.0 ± 0.0
1.562TyrSer: 1.562 ± 0.852
1.562TyrThr: 1.562 ± 0.852
1.562TyrVal: 1.562 ± 1.513
1.562TyrTrp: 1.562 ± 1.513
1.562TyrTyr: 1.562 ± 0.852
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (641 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski