Amino acid dipepetide frequency for Cyphomyrmex costatus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.885AlaAla: 4.885 ± 0.05	1.228AlaCys: 1.228 ± 0.025	2.783AlaAsp: 2.783 ± 0.022	3.605AlaGlu: 3.605 ± 0.029	2.134AlaPhe: 2.134 ± 0.02	3.214AlaGly: 3.214 ± 0.029	1.387AlaHis: 1.387 ± 0.016	3.676AlaIle: 3.676 ± 0.026	3.573AlaLys: 3.573 ± 0.03	5.468AlaLeu: 5.468 ± 0.041	1.458AlaMet: 1.458 ± 0.015	2.726AlaAsn: 2.726 ± 0.024	2.539AlaPro: 2.539 ± 0.025	2.171AlaGln: 2.171 ± 0.021	3.566AlaArg: 3.566 ± 0.026	4.707AlaSer: 4.707 ± 0.033	3.929AlaThr: 3.929 ± 0.031	3.865AlaVal: 3.865 ± 0.028	0.618AlaTrp: 0.618 ± 0.01	1.67AlaTyr: 1.67 ± 0.016	0.001AlaXaa: 0.001 ± 0.0
Cys	1.158CysAla: 1.158 ± 0.015	0.5CysCys: 0.5 ± 0.01	1.157CysAsp: 1.157 ± 0.018	1.24CysGlu: 1.24 ± 0.024	0.787CysPhe: 0.787 ± 0.011	1.375CysGly: 1.375 ± 0.035	0.568CysHis: 0.568 ± 0.012	1.34CysIle: 1.34 ± 0.03	1.271CysLys: 1.271 ± 0.02	1.851CysLeu: 1.851 ± 0.028	0.431CysMet: 0.431 ± 0.009	1.119CysAsn: 1.119 ± 0.018	1.016CysPro: 1.016 ± 0.034	0.78CysGln: 0.78 ± 0.021	1.246CysArg: 1.246 ± 0.032	1.629CysSer: 1.629 ± 0.029	1.212CysThr: 1.212 ± 0.023	1.291CysVal: 1.291 ± 0.027	0.238CysTrp: 0.238 ± 0.006	0.625CysTyr: 0.625 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	2.992AspAla: 2.992 ± 0.019	1.074AspCys: 1.074 ± 0.021	3.645AspAsp: 3.645 ± 0.037	4.024AspGlu: 4.024 ± 0.03	2.076AspPhe: 2.076 ± 0.02	2.939AspGly: 2.939 ± 0.028	1.125AspHis: 1.125 ± 0.013	3.737AspIle: 3.737 ± 0.031	3.452AspLys: 3.452 ± 0.03	4.64AspLeu: 4.64 ± 0.031	1.19AspMet: 1.19 ± 0.012	2.886AspAsn: 2.886 ± 0.023	2.223AspPro: 2.223 ± 0.031	1.599AspGln: 1.599 ± 0.016	2.792AspArg: 2.792 ± 0.031	4.216AspSer: 4.216 ± 0.036	3.013AspThr: 3.013 ± 0.024	3.544AspVal: 3.544 ± 0.028	0.599AspTrp: 0.599 ± 0.011	1.828AspTyr: 1.828 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	3.711GluAla: 3.711 ± 0.029	1.271GluCys: 1.271 ± 0.037	3.973GluAsp: 3.973 ± 0.03	5.947GluGlu: 5.947 ± 0.066	2.175GluPhe: 2.175 ± 0.022	2.812GluGly: 2.812 ± 0.026	1.508GluHis: 1.508 ± 0.016	4.344GluIle: 4.344 ± 0.036	5.202GluLys: 5.202 ± 0.048	5.573GluLeu: 5.573 ± 0.037	1.561GluMet: 1.561 ± 0.017	3.986GluAsn: 3.986 ± 0.03	2.225GluPro: 2.225 ± 0.026	2.646GluGln: 2.646 ± 0.025	4.238GluArg: 4.238 ± 0.039	4.568GluSer: 4.568 ± 0.041	3.849GluThr: 3.849 ± 0.035	3.43GluVal: 3.43 ± 0.029	0.674GluTrp: 0.674 ± 0.012	2.021GluTyr: 2.021 ± 0.021	0.001GluXaa: 0.001 ± 0.0
Phe	2.119PheAla: 2.119 ± 0.02	0.889PheCys: 0.889 ± 0.012	2.081PheAsp: 2.081 ± 0.018	2.18PheGlu: 2.18 ± 0.022	1.559PhePhe: 1.559 ± 0.019	2.063PheGly: 2.063 ± 0.021	1.054PheHis: 1.054 ± 0.015	2.313PheIle: 2.313 ± 0.025	2.141PheLys: 2.141 ± 0.02	3.706PheLeu: 3.706 ± 0.031	0.804PheMet: 0.804 ± 0.013	1.853PheAsn: 1.853 ± 0.019	1.688PhePro: 1.688 ± 0.017	1.392PheGln: 1.392 ± 0.014	1.935PheArg: 1.935 ± 0.018	2.999PheSer: 2.999 ± 0.027	2.099PheThr: 2.099 ± 0.022	2.409PheVal: 2.409 ± 0.02	0.439PheTrp: 0.439 ± 0.008	1.35PheTyr: 1.35 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	2.945GlyAla: 2.945 ± 0.027	1.018GlyCys: 1.018 ± 0.017	2.643GlyAsp: 2.643 ± 0.028	2.936GlyGlu: 2.936 ± 0.034	1.995GlyPhe: 1.995 ± 0.025	3.958GlyGly: 3.958 ± 0.05	1.387GlyHis: 1.387 ± 0.019	3.262GlyIle: 3.262 ± 0.025	3.267GlyLys: 3.267 ± 0.027	4.246GlyLeu: 4.246 ± 0.032	1.147GlyMet: 1.147 ± 0.015	2.619GlyAsn: 2.619 ± 0.025	2.238GlyPro: 2.238 ± 0.038	1.883GlyGln: 1.883 ± 0.02	3.134GlyArg: 3.134 ± 0.024	4.236GlySer: 4.236 ± 0.034	3.146GlyThr: 3.146 ± 0.033	3.026GlyVal: 3.026 ± 0.025	0.659GlyTrp: 0.659 ± 0.011	1.936GlyTyr: 1.936 ± 0.025	0.001GlyXaa: 0.001 ± 0.0
His	1.421HisAla: 1.421 ± 0.013	0.624HisCys: 0.624 ± 0.011	1.178HisAsp: 1.178 ± 0.015	1.44HisGlu: 1.44 ± 0.018	1.04HisPhe: 1.04 ± 0.013	1.349HisGly: 1.349 ± 0.017	1.082HisHis: 1.082 ± 0.026	1.555HisIle: 1.555 ± 0.015	1.399HisLys: 1.399 ± 0.016	2.402HisLeu: 2.402 ± 0.023	0.59HisMet: 0.59 ± 0.011	1.254HisAsn: 1.254 ± 0.014	1.375HisPro: 1.375 ± 0.021	1.085HisGln: 1.085 ± 0.016	1.581HisArg: 1.581 ± 0.017	1.986HisSer: 1.986 ± 0.018	1.43HisThr: 1.43 ± 0.016	1.636HisVal: 1.636 ± 0.016	0.288HisTrp: 0.288 ± 0.006	0.916HisTyr: 0.916 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	3.859IleAla: 3.859 ± 0.027	1.393IleCys: 1.393 ± 0.024	3.5IleAsp: 3.5 ± 0.026	3.996IleGlu: 3.996 ± 0.033	2.561IlePhe: 2.561 ± 0.026	3.053IleGly: 3.053 ± 0.026	1.519IleHis: 1.519 ± 0.018	4.063IleIle: 4.063 ± 0.04	4.021IleLys: 4.021 ± 0.031	5.955IleLeu: 5.955 ± 0.043	1.389IleMet: 1.389 ± 0.018	3.408IleAsn: 3.408 ± 0.034	3.017IlePro: 3.017 ± 0.025	2.377IleGln: 2.377 ± 0.023	3.235IleArg: 3.235 ± 0.023	4.943IleSer: 4.943 ± 0.029	3.649IleThr: 3.649 ± 0.032	3.884IleVal: 3.884 ± 0.032	0.611IleTrp: 0.611 ± 0.011	2.056IleTyr: 2.056 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.191LysAla: 3.191 ± 0.025	1.328LysCys: 1.328 ± 0.023	3.581LysAsp: 3.581 ± 0.032	4.905LysGlu: 4.905 ± 0.05	2.238LysPhe: 2.238 ± 0.021	2.614LysGly: 2.614 ± 0.03	1.643LysHis: 1.643 ± 0.019	4.335LysIle: 4.335 ± 0.033	5.49LysLys: 5.49 ± 0.055	5.905LysLeu: 5.905 ± 0.037	1.537LysMet: 1.537 ± 0.015	3.648LysAsn: 3.648 ± 0.033	2.711LysPro: 2.711 ± 0.038	2.683LysGln: 2.683 ± 0.023	4.222LysArg: 4.222 ± 0.031	4.812LysSer: 4.812 ± 0.043	3.732LysThr: 3.732 ± 0.026	3.374LysVal: 3.374 ± 0.028	0.703LysTrp: 0.703 ± 0.01	2.272LysTyr: 2.272 ± 0.022	0.001LysXaa: 0.001 ± 0.0
Leu	5.564LeuAla: 5.564 ± 0.04	1.862LeuCys: 1.862 ± 0.023	4.627LeuAsp: 4.627 ± 0.026	5.97LeuGlu: 5.97 ± 0.039	3.235LeuPhe: 3.235 ± 0.029	4.18LeuGly: 4.18 ± 0.03	2.564LeuHis: 2.564 ± 0.022	5.118LeuIle: 5.118 ± 0.035	5.993LeuLys: 5.993 ± 0.04	8.852LeuLeu: 8.852 ± 0.063	1.999LeuMet: 1.999 ± 0.018	4.515LeuAsn: 4.515 ± 0.033	4.808LeuPro: 4.808 ± 0.027	4.408LeuGln: 4.408 ± 0.031	5.499LeuArg: 5.499 ± 0.034	7.373LeuSer: 7.373 ± 0.038	5.169LeuThr: 5.169 ± 0.03	4.771LeuVal: 4.771 ± 0.033	0.915LeuTrp: 0.915 ± 0.013	2.951LeuTyr: 2.951 ± 0.026	0.001LeuXaa: 0.001 ± 0.0
Met	1.426MetAla: 1.426 ± 0.016	0.453MetCys: 0.453 ± 0.008	1.273MetAsp: 1.273 ± 0.015	1.634MetGlu: 1.634 ± 0.016	0.846MetPhe: 0.846 ± 0.012	1.045MetGly: 1.045 ± 0.015	0.562MetHis: 0.562 ± 0.01	1.335MetIle: 1.335 ± 0.018	1.572MetLys: 1.572 ± 0.014	2.071MetLeu: 2.071 ± 0.02	0.606MetMet: 0.606 ± 0.013	1.121MetAsn: 1.121 ± 0.014	1.083MetPro: 1.083 ± 0.013	1.048MetGln: 1.048 ± 0.013	1.29MetArg: 1.29 ± 0.015	1.805MetSer: 1.805 ± 0.016	1.319MetThr: 1.319 ± 0.014	1.174MetVal: 1.174 ± 0.012	0.237MetTrp: 0.237 ± 0.005	0.776MetTyr: 0.776 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.039AsnAla: 3.039 ± 0.029	1.092AsnCys: 1.092 ± 0.019	2.968AsnAsp: 2.968 ± 0.024	3.437AsnGlu: 3.437 ± 0.025	2.02AsnPhe: 2.02 ± 0.019	2.819AsnGly: 2.819 ± 0.023	1.225AsnHis: 1.225 ± 0.016	3.789AsnIle: 3.789 ± 0.027	3.407AsnLys: 3.407 ± 0.035	4.689AsnLeu: 4.689 ± 0.033	1.236AsnMet: 1.236 ± 0.014	3.535AsnAsn: 3.535 ± 0.034	2.171AsnPro: 2.171 ± 0.029	1.873AsnGln: 1.873 ± 0.021	2.608AsnArg: 2.608 ± 0.02	4.091AsnSer: 4.091 ± 0.029	3.017AsnThr: 3.017 ± 0.026	3.659AsnVal: 3.659 ± 0.025	0.506AsnTrp: 0.506 ± 0.009	1.766AsnTyr: 1.766 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	2.824ProAla: 2.824 ± 0.023	0.862ProCys: 0.862 ± 0.042	2.267ProAsp: 2.267 ± 0.023	2.894ProGlu: 2.894 ± 0.036	1.651ProPhe: 1.651 ± 0.015	2.667ProGly: 2.667 ± 0.07	1.209ProHis: 1.209 ± 0.016	2.763ProIle: 2.763 ± 0.024	2.568ProLys: 2.568 ± 0.03	4.128ProLeu: 4.128 ± 0.028	0.98ProMet: 0.98 ± 0.015	2.191ProAsn: 2.191 ± 0.022	3.882ProPro: 3.882 ± 0.05	1.912ProGln: 1.912 ± 0.02	2.765ProArg: 2.765 ± 0.025	4.22ProSer: 4.22 ± 0.036	3.056ProThr: 3.056 ± 0.028	2.95ProVal: 2.95 ± 0.027	0.481ProTrp: 0.481 ± 0.01	1.526ProTyr: 1.526 ± 0.02	0.001ProXaa: 0.001 ± 0.0
Gln	2.253GlnAla: 2.253 ± 0.024	0.814GlnCys: 0.814 ± 0.02	1.903GlnAsp: 1.903 ± 0.016	2.778GlnGlu: 2.778 ± 0.025	1.376GlnPhe: 1.376 ± 0.012	1.673GlnGly: 1.673 ± 0.021	1.221GlnHis: 1.221 ± 0.016	2.367GlnIle: 2.367 ± 0.021	2.552GlnLys: 2.552 ± 0.021	3.754GlnLeu: 3.754 ± 0.03	0.956GlnMet: 0.956 ± 0.016	2.266GlnAsn: 2.266 ± 0.022	1.895GlnPro: 1.895 ± 0.023	3.29GlnGln: 3.29 ± 0.072	2.566GlnArg: 2.566 ± 0.025	3.041GlnSer: 3.041 ± 0.029	2.322GlnThr: 2.322 ± 0.024	2.116GlnVal: 2.116 ± 0.023	0.476GlnTrp: 0.476 ± 0.009	1.306GlnTyr: 1.306 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	3.322ArgAla: 3.322 ± 0.027	1.255ArgCys: 1.255 ± 0.022	3.116ArgAsp: 3.116 ± 0.031	3.975ArgGlu: 3.975 ± 0.033	2.133ArgPhe: 2.133 ± 0.023	3.084ArgGly: 3.084 ± 0.029	1.645ArgHis: 1.645 ± 0.02	3.453ArgIle: 3.453 ± 0.028	4.172ArgLys: 4.172 ± 0.03	5.209ArgLeu: 5.209 ± 0.032	1.298ArgMet: 1.298 ± 0.012	3.12ArgAsn: 3.12 ± 0.025	2.546ArgPro: 2.546 ± 0.031	2.404ArgGln: 2.404 ± 0.02	4.747ArgArg: 4.747 ± 0.045	4.613ArgSer: 4.613 ± 0.041	3.145ArgThr: 3.145 ± 0.023	3.174ArgVal: 3.174 ± 0.024	0.667ArgTrp: 0.667 ± 0.011	1.99ArgTyr: 1.99 ± 0.019	0.001ArgXaa: 0.001 ± 0.0
Ser	4.509SerAla: 4.509 ± 0.032	1.579SerCys: 1.579 ± 0.03	4.263SerAsp: 4.263 ± 0.031	4.703SerGlu: 4.703 ± 0.038	2.887SerPhe: 2.887 ± 0.025	4.43SerGly: 4.43 ± 0.034	1.915SerHis: 1.915 ± 0.02	4.707SerIle: 4.707 ± 0.029	4.753SerLys: 4.753 ± 0.037	7.112SerLeu: 7.112 ± 0.039	1.73SerMet: 1.73 ± 0.017	4.301SerAsn: 4.301 ± 0.034	4.29SerPro: 4.29 ± 0.046	3.122SerGln: 3.122 ± 0.029	4.676SerArg: 4.676 ± 0.039	8.477SerSer: 8.477 ± 0.078	5.373SerThr: 5.373 ± 0.042	4.751SerVal: 4.751 ± 0.03	0.854SerTrp: 0.854 ± 0.012	2.396SerTyr: 2.396 ± 0.022	0.001SerXaa: 0.001 ± 0.0
Thr	3.754ThrAla: 3.754 ± 0.027	1.254ThrCys: 1.254 ± 0.024	3.082ThrAsp: 3.082 ± 0.024	3.721ThrGlu: 3.721 ± 0.038	2.217ThrPhe: 2.217 ± 0.021	3.205ThrGly: 3.205 ± 0.029	1.35ThrHis: 1.35 ± 0.016	3.735ThrIle: 3.735 ± 0.029	3.572ThrLys: 3.572 ± 0.028	5.411ThrLeu: 5.411 ± 0.035	1.395ThrMet: 1.395 ± 0.016	3.018ThrAsn: 3.018 ± 0.023	3.156ThrPro: 3.156 ± 0.036	2.1ThrGln: 2.1 ± 0.02	3.155ThrArg: 3.155 ± 0.029	5.317ThrSer: 5.317 ± 0.037	4.447ThrThr: 4.447 ± 0.059	3.902ThrVal: 3.902 ± 0.027	0.659ThrTrp: 0.659 ± 0.01	1.817ThrTyr: 1.817 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	3.871ValAla: 3.871 ± 0.029	1.346ValCys: 1.346 ± 0.023	3.172ValAsp: 3.172 ± 0.026	3.725ValGlu: 3.725 ± 0.031	2.245ValPhe: 2.245 ± 0.022	2.884ValGly: 2.884 ± 0.023	1.498ValHis: 1.498 ± 0.017	3.743ValIle: 3.743 ± 0.029	3.695ValLys: 3.695 ± 0.029	5.317ValLeu: 5.317 ± 0.037	1.314ValMet: 1.314 ± 0.015	2.977ValAsn: 2.977 ± 0.024	3.043ValPro: 3.043 ± 0.026	2.431ValGln: 2.431 ± 0.022	3.193ValArg: 3.193 ± 0.024	4.611ValSer: 4.611 ± 0.026	3.906ValThr: 3.906 ± 0.028	3.718ValVal: 3.718 ± 0.031	0.638ValTrp: 0.638 ± 0.011	1.924ValTyr: 1.924 ± 0.02	0.001ValXaa: 0.001 ± 0.0
Trp	0.554TrpAla: 0.554 ± 0.011	0.232TrpCys: 0.232 ± 0.006	0.595TrpAsp: 0.595 ± 0.011	0.623TrpGlu: 0.623 ± 0.01	0.442TrpPhe: 0.442 ± 0.009	0.507TrpGly: 0.507 ± 0.01	0.277TrpHis: 0.277 ± 0.007	0.728TrpIle: 0.728 ± 0.012	0.759TrpLys: 0.759 ± 0.013	1.104TrpLeu: 1.104 ± 0.015	0.288TrpMet: 0.288 ± 0.007	0.608TrpAsn: 0.608 ± 0.01	0.422TrpPro: 0.422 ± 0.008	0.48TrpGln: 0.48 ± 0.009	0.717TrpArg: 0.717 ± 0.01	0.815TrpSer: 0.815 ± 0.011	0.586TrpThr: 0.586 ± 0.011	0.504TrpVal: 0.504 ± 0.01	0.179TrpTrp: 0.179 ± 0.006	0.376TrpTyr: 0.376 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.805TyrAla: 1.805 ± 0.02	0.764TyrCys: 0.764 ± 0.012	1.787TyrAsp: 1.787 ± 0.018	1.982TyrGlu: 1.982 ± 0.02	1.454TyrPhe: 1.454 ± 0.016	1.813TyrGly: 1.813 ± 0.017	0.889TyrHis: 0.889 ± 0.01	2.128TyrIle: 2.128 ± 0.023	2.063TyrLys: 2.063 ± 0.021	2.982TyrLeu: 2.982 ± 0.025	0.768TyrMet: 0.768 ± 0.011	1.796TyrAsn: 1.796 ± 0.019	1.467TyrPro: 1.467 ± 0.023	1.241TyrGln: 1.241 ± 0.015	1.899TyrArg: 1.899 ± 0.021	2.369TyrSer: 2.369 ± 0.02	1.868TyrThr: 1.868 ± 0.021	2.075TyrVal: 2.075 ± 0.018	0.354TyrTrp: 0.354 ± 0.008	1.299TyrTyr: 1.299 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	1.107XaaXaa: 1.107 ± 0.194

Statistics based on 15716 proteins (7198715 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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