Spheniscid alphaherpesvirus 1

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Mardivirus

Average proteome isoelectric point is 6.44

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 83 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1R3TFR1|A0A1R3TFR1_9ALPH Transcriptional regulator ICP4 OS=Spheniscid alphaherpesvirus 1 OX=2560777 GN=ICP4 PE=3 SV=1
MM1 pKa = 7.51GAPATFITYY10 pKa = 7.16TLRR13 pKa = 11.84GVRR16 pKa = 11.84SSQPWAVPDD25 pKa = 3.68YY26 pKa = 9.81EE27 pKa = 5.24QIVCSCDD34 pKa = 2.67GGTRR38 pKa = 11.84SVTVGSLSRR47 pKa = 11.84CDD49 pKa = 3.59ILPPGNFILQKK60 pKa = 10.74GPAGTLLVLDD70 pKa = 5.32CEE72 pKa = 4.9PEE74 pKa = 4.09FCSYY78 pKa = 11.29LLRR81 pKa = 11.84DD82 pKa = 4.06CGVHH86 pKa = 5.83YY87 pKa = 10.24GQLSSIPWSLGVFPFSSCTVVGRR110 pKa = 11.84DD111 pKa = 3.03RR112 pKa = 11.84CVDD115 pKa = 3.25SSNACGVLTVTWLRR129 pKa = 11.84EE130 pKa = 4.08SVYY133 pKa = 9.53VTLTVYY139 pKa = 10.7GSRR142 pKa = 11.84DD143 pKa = 3.06ISRR146 pKa = 11.84DD147 pKa = 3.04EE148 pKa = 4.47HH149 pKa = 7.99GLVNDD154 pKa = 4.42GAEE157 pKa = 4.09CDD159 pKa = 3.9GPNAEE164 pKa = 5.47SSTLCCCGGEE174 pKa = 4.42DD175 pKa = 5.14SISGNDD181 pKa = 3.35AVEE184 pKa = 4.3VSDD187 pKa = 5.49GMNDD191 pKa = 3.67LLAEE195 pKa = 5.44AIRR198 pKa = 11.84EE199 pKa = 4.01AALNTEE205 pKa = 4.49QYY207 pKa = 10.96DD208 pKa = 3.64ADD210 pKa = 4.18LTSLLNSISPKK221 pKa = 10.54EE222 pKa = 4.0FFADD226 pKa = 3.37QTFVQQ231 pKa = 4.12

Molecular weight: 24.75 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1R3TEQ0|A0A1R3TEQ0_9ALPH Envelope glycoprotein E OS=Spheniscid alphaherpesvirus 1 OX=2560777 GN=US8 PE=3 SV=1
MM1 pKa = 7.28FGVASLATSNDD12 pKa = 2.89FKK14 pKa = 11.62VFLAANPHH22 pKa = 5.85ACAKK26 pKa = 10.14LRR28 pKa = 11.84AAMNKK33 pKa = 9.55KK34 pKa = 10.71GEE36 pKa = 4.24GSSIDD41 pKa = 3.72CMRR44 pKa = 11.84EE45 pKa = 3.66CGNDD49 pKa = 3.05RR50 pKa = 11.84KK51 pKa = 9.57YY52 pKa = 7.31TTSGHH57 pKa = 5.33GKK59 pKa = 9.44ALKK62 pKa = 10.38RR63 pKa = 11.84GAKK66 pKa = 9.38SNRR69 pKa = 11.84SSDD72 pKa = 3.01IDD74 pKa = 3.88EE75 pKa = 4.47NDD77 pKa = 3.27YY78 pKa = 11.57AAGSASSAYY87 pKa = 10.11VSRR90 pKa = 11.84GDD92 pKa = 3.39VDD94 pKa = 3.95VGAGTSKK101 pKa = 10.61RR102 pKa = 11.84HH103 pKa = 4.07TTTVQRR109 pKa = 11.84RR110 pKa = 11.84RR111 pKa = 11.84RR112 pKa = 11.84KK113 pKa = 8.53STGSTSLEE121 pKa = 4.31CNSSDD126 pKa = 3.91RR127 pKa = 11.84LNEE130 pKa = 3.87VPSYY134 pKa = 10.14RR135 pKa = 11.84GRR137 pKa = 11.84RR138 pKa = 11.84SSLVTPGSKK147 pKa = 10.02QLMQNSRR154 pKa = 11.84EE155 pKa = 4.13SRR157 pKa = 11.84SCLRR161 pKa = 11.84DD162 pKa = 3.04RR163 pKa = 11.84KK164 pKa = 10.32SALKK168 pKa = 10.37RR169 pKa = 11.84QQ170 pKa = 3.53

Molecular weight: 18.47 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

83

0

83

43321

76

3741

521.9

58.07

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.908 ± 0.334

2.318 ± 0.139

6.117 ± 0.148

5.679 ± 0.158

3.76 ± 0.159

5.983 ± 0.136

2.138 ± 0.068

5.141 ± 0.185

4.173 ± 0.166

8.485 ± 0.224

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.417 ± 0.105

4.303 ± 0.131

4.944 ± 0.204

2.881 ± 0.151

6.916 ± 0.169

8.779 ± 0.232

6.683 ± 0.172

6.865 ± 0.168

1.094 ± 0.057

3.416 ± 0.151
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski