Amino acid dipepetide frequency for Bat tymo-like virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.214AlaAla: 6.214 ± 0.898
1.554AlaCys: 1.554 ± 0.747
1.036AlaAsp: 1.036 ± 0.498
0.518AlaGlu: 0.518 ± 0.249
4.143AlaPhe: 4.143 ± 1.992
2.589AlaGly: 2.589 ± 1.245
2.071AlaHis: 2.071 ± 0.947
2.589AlaIle: 2.589 ± 0.698
1.554AlaLys: 1.554 ± 0.747
8.804AlaLeu: 8.804 ± 3.538
1.036AlaMet: 1.036 ± 1.445
1.036AlaAsn: 1.036 ± 1.445
6.732AlaPro: 6.732 ± 0.649
1.554AlaGln: 1.554 ± 1.196
2.589AlaArg: 2.589 ± 0.698
7.768AlaSer: 7.768 ± 0.15
2.071AlaThr: 2.071 ± 2.89
5.697AlaVal: 5.697 ± 1.147
1.554AlaTrp: 1.554 ± 0.747
2.071AlaTyr: 2.071 ± 0.947
0.0AlaXaa: 0.0 ± 0.0
Cys
0.518CysAla: 0.518 ± 0.249
0.0CysCys: 0.0 ± 0.0
0.518CysAsp: 0.518 ± 1.694
0.518CysGlu: 0.518 ± 1.694
1.554CysPhe: 1.554 ± 0.747
1.554CysGly: 1.554 ± 0.747
1.036CysHis: 1.036 ± 0.498
2.589CysIle: 2.589 ± 1.245
0.0CysLys: 0.0 ± 0.0
2.071CysLeu: 2.071 ± 0.996
0.0CysMet: 0.0 ± 0.0
0.518CysAsn: 0.518 ± 0.249
1.036CysPro: 1.036 ± 0.498
1.036CysGln: 1.036 ± 0.498
0.518CysArg: 0.518 ± 0.249
1.554CysSer: 1.554 ± 0.747
0.0CysThr: 0.0 ± 0.0
0.518CysVal: 0.518 ± 0.249
0.0CysTrp: 0.0 ± 0.0
0.518CysTyr: 0.518 ± 0.249
0.0CysXaa: 0.0 ± 0.0
Asp
4.143AspAla: 4.143 ± 3.837
0.518AspCys: 0.518 ± 0.249
3.107AspAsp: 3.107 ± 1.494
0.518AspGlu: 0.518 ± 0.249
1.554AspPhe: 1.554 ± 0.747
1.036AspGly: 1.036 ± 0.498
2.589AspHis: 2.589 ± 1.245
3.107AspIle: 3.107 ± 0.449
1.554AspLys: 1.554 ± 0.747
7.25AspLeu: 7.25 ± 0.399
0.518AspMet: 0.518 ± 1.694
2.071AspAsn: 2.071 ± 0.947
6.214AspPro: 6.214 ± 2.989
1.036AspGln: 1.036 ± 0.498
3.107AspArg: 3.107 ± 0.449
6.732AspSer: 6.732 ± 0.649
1.036AspThr: 1.036 ± 0.498
3.625AspVal: 3.625 ± 2.143
1.036AspTrp: 1.036 ± 1.445
2.071AspTyr: 2.071 ± 0.996
0.0AspXaa: 0.0 ± 0.0
Glu
1.554GluAla: 1.554 ± 0.747
1.036GluCys: 1.036 ± 0.498
0.0GluAsp: 0.0 ± 0.0
1.036GluGlu: 1.036 ± 0.498
1.554GluPhe: 1.554 ± 0.747
0.518GluGly: 0.518 ± 0.249
0.518GluHis: 0.518 ± 1.694
2.589GluIle: 2.589 ± 1.245
0.0GluLys: 0.0 ± 0.0
5.179GluLeu: 5.179 ± 1.396
0.0GluMet: 0.0 ± 0.0
1.036GluAsn: 1.036 ± 0.498
4.661GluPro: 4.661 ± 2.241
1.554GluGln: 1.554 ± 1.196
0.518GluArg: 0.518 ± 0.249
2.071GluSer: 2.071 ± 0.996
2.071GluThr: 2.071 ± 0.996
1.036GluVal: 1.036 ± 3.388
0.0GluTrp: 0.0 ± 0.0
1.036GluTyr: 1.036 ± 0.498
0.0GluXaa: 0.0 ± 0.0
Phe
3.107PheAla: 3.107 ± 1.494
1.554PheCys: 1.554 ± 0.747
6.732PheAsp: 6.732 ± 1.295
1.554PheGlu: 1.554 ± 0.747
3.107PhePhe: 3.107 ± 0.449
3.107PheGly: 3.107 ± 1.494
2.589PheHis: 2.589 ± 1.245
3.625PheIle: 3.625 ± 1.743
3.625PheLys: 3.625 ± 0.2
3.625PheLeu: 3.625 ± 0.2
1.036PheMet: 1.036 ± 1.445
1.036PheAsn: 1.036 ± 0.498
2.589PhePro: 2.589 ± 1.245
2.589PheGln: 2.589 ± 0.698
3.625PheArg: 3.625 ± 1.743
9.322PheSer: 9.322 ± 1.346
2.071PheThr: 2.071 ± 0.947
1.554PheVal: 1.554 ± 1.196
0.0PheTrp: 0.0 ± 0.0
0.518PheTyr: 0.518 ± 0.249
0.0PheXaa: 0.0 ± 0.0
Gly
1.036GlyAla: 1.036 ± 1.445
1.554GlyCys: 1.554 ± 0.747
4.143GlyAsp: 4.143 ± 1.894
1.554GlyGlu: 1.554 ± 0.747
1.554GlyPhe: 1.554 ± 1.196
1.554GlyGly: 1.554 ± 1.196
2.071GlyHis: 2.071 ± 0.996
2.071GlyIle: 2.071 ± 0.996
1.554GlyLys: 1.554 ± 0.747
1.554GlyLeu: 1.554 ± 0.747
0.0GlyMet: 0.0 ± 0.0
0.518GlyAsn: 0.518 ± 0.249
4.143GlyPro: 4.143 ± 1.894
0.518GlyGln: 0.518 ± 0.249
1.036GlyArg: 1.036 ± 0.498
2.071GlySer: 2.071 ± 0.996
3.107GlyThr: 3.107 ± 2.392
1.554GlyVal: 1.554 ± 0.747
0.0GlyTrp: 0.0 ± 0.0
1.554GlyTyr: 1.554 ± 0.747
0.0GlyXaa: 0.0 ± 0.0
His
2.071HisAla: 2.071 ± 0.996
0.518HisCys: 0.518 ± 0.249
2.071HisAsp: 2.071 ± 0.947
0.518HisGlu: 0.518 ± 0.249
0.518HisPhe: 0.518 ± 0.249
0.518HisGly: 0.518 ± 0.249
0.0HisHis: 0.0 ± 0.0
1.554HisIle: 1.554 ± 0.747
1.036HisLys: 1.036 ± 0.498
6.732HisLeu: 6.732 ± 3.238
0.0HisMet: 0.0 ± 0.0
1.554HisAsn: 1.554 ± 0.747
3.107HisPro: 3.107 ± 0.449
2.589HisGln: 2.589 ± 1.245
0.518HisArg: 0.518 ± 0.249
4.661HisSer: 4.661 ± 2.241
1.554HisThr: 1.554 ± 0.747
3.625HisVal: 3.625 ± 2.143
1.554HisTrp: 1.554 ± 1.196
0.518HisTyr: 0.518 ± 0.249
0.0HisXaa: 0.0 ± 0.0
Ile
4.143IleAla: 4.143 ± 0.049
1.036IleCys: 1.036 ± 0.498
2.071IleAsp: 2.071 ± 0.947
2.071IleGlu: 2.071 ± 0.996
2.071IlePhe: 2.071 ± 0.947
2.589IleGly: 2.589 ± 0.698
2.589IleHis: 2.589 ± 1.245
2.589IleIle: 2.589 ± 1.245
1.036IleLys: 1.036 ± 1.445
8.286IleLeu: 8.286 ± 3.985
0.0IleMet: 0.0 ± 0.0
3.625IleAsn: 3.625 ± 0.2
6.214IlePro: 6.214 ± 0.898
0.0IleGln: 0.0 ± 0.0
3.107IleArg: 3.107 ± 1.494
7.25IleSer: 7.25 ± 0.399
3.107IleThr: 3.107 ± 1.494
3.107IleVal: 3.107 ± 0.449
0.0IleTrp: 0.0 ± 0.0
3.107IleTyr: 3.107 ± 1.494
0.0IleXaa: 0.0 ± 0.0
Lys
2.071LysAla: 2.071 ± 0.996
0.0LysCys: 0.0 ± 0.0
1.036LysAsp: 1.036 ± 0.498
1.036LysGlu: 1.036 ± 0.498
2.071LysPhe: 2.071 ± 0.947
0.0LysGly: 0.0 ± 0.0
1.036LysHis: 1.036 ± 1.445
2.071LysIle: 2.071 ± 0.996
3.625LysLys: 3.625 ± 1.743
4.143LysLeu: 4.143 ± 3.837
2.071LysMet: 2.071 ± 0.996
1.036LysAsn: 1.036 ± 0.498
1.554LysPro: 1.554 ± 0.747
0.518LysGln: 0.518 ± 0.249
1.036LysArg: 1.036 ± 0.498
3.625LysSer: 3.625 ± 0.2
3.625LysThr: 3.625 ± 1.743
2.071LysVal: 2.071 ± 0.947
0.518LysTrp: 0.518 ± 1.694
1.554LysTyr: 1.554 ± 0.747
0.0LysXaa: 0.0 ± 0.0
Leu
7.768LeuAla: 7.768 ± 4.037
1.554LeuCys: 1.554 ± 0.747
8.804LeuAsp: 8.804 ± 1.595
3.107LeuGlu: 3.107 ± 2.392
9.322LeuPhe: 9.322 ± 2.54
3.625LeuGly: 3.625 ± 2.143
5.179LeuHis: 5.179 ± 0.547
5.697LeuIle: 5.697 ± 0.796
4.143LeuLys: 4.143 ± 1.992
12.947LeuLeu: 12.947 ± 1.546
0.518LeuMet: 0.518 ± 0.418
3.107LeuAsn: 3.107 ± 0.449
11.393LeuPro: 11.393 ± 4.236
2.071LeuGln: 2.071 ± 0.996
8.804LeuArg: 8.804 ± 2.291
15.536LeuSer: 15.536 ± 0.301
7.768LeuThr: 7.768 ± 3.736
7.25LeuVal: 7.25 ± 0.399
2.589LeuTrp: 2.589 ± 1.245
2.071LeuTyr: 2.071 ± 0.996
0.0LeuXaa: 0.0 ± 0.0
Met
2.071MetAla: 2.071 ± 0.947
0.0MetCys: 0.0 ± 0.0
0.518MetAsp: 0.518 ± 0.249
0.0MetGlu: 0.0 ± 0.0
0.518MetPhe: 0.518 ± 0.249
0.518MetGly: 0.518 ± 0.249
0.0MetHis: 0.0 ± 0.0
0.518MetIle: 0.518 ± 0.249
0.0MetLys: 0.0 ± 0.0
1.554MetLeu: 1.554 ± 1.196
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.107MetPro: 3.107 ± 0.449
0.0MetGln: 0.0 ± 0.0
1.554MetArg: 1.554 ± 0.747
1.036MetSer: 1.036 ± 3.388
1.036MetThr: 1.036 ± 0.498
0.518MetVal: 0.518 ± 0.249
0.0MetTrp: 0.0 ± 0.0
0.518MetTyr: 0.518 ± 0.249
0.0MetXaa: 0.0 ± 0.0
Asn
1.554AsnAla: 1.554 ± 0.747
1.036AsnCys: 1.036 ± 0.498
4.143AsnAsp: 4.143 ± 1.992
1.036AsnGlu: 1.036 ± 0.498
2.071AsnPhe: 2.071 ± 0.996
0.0AsnGly: 0.0 ± 0.0
3.625AsnHis: 3.625 ± 0.2
1.036AsnIle: 1.036 ± 1.445
1.036AsnLys: 1.036 ± 1.445
4.661AsnLeu: 4.661 ± 1.645
0.0AsnMet: 0.0 ± 0.0
1.554AsnAsn: 1.554 ± 0.747
4.143AsnPro: 4.143 ± 0.049
1.036AsnGln: 1.036 ± 0.498
0.518AsnArg: 0.518 ± 0.249
4.661AsnSer: 4.661 ± 0.298
2.589AsnThr: 2.589 ± 2.641
2.071AsnVal: 2.071 ± 0.947
0.0AsnTrp: 0.0 ± 0.0
0.518AsnTyr: 0.518 ± 0.249
0.0AsnXaa: 0.0 ± 0.0
Pro
6.214ProAla: 6.214 ± 2.841
1.036ProCys: 1.036 ± 0.498
2.589ProAsp: 2.589 ± 1.245
3.625ProGlu: 3.625 ± 0.2
4.143ProPhe: 4.143 ± 1.894
4.143ProGly: 4.143 ± 0.049
2.589ProHis: 2.589 ± 1.245
6.214ProIle: 6.214 ± 0.898
2.589ProLys: 2.589 ± 1.245
12.429ProLeu: 12.429 ± 2.091
1.554ProMet: 1.554 ± 0.747
5.697ProAsn: 5.697 ± 2.739
5.179ProPro: 5.179 ± 2.49
2.071ProGln: 2.071 ± 0.996
5.697ProArg: 5.697 ± 3.09
14.5ProSer: 14.5 ± 4.685
3.107ProThr: 3.107 ± 2.392
3.107ProVal: 3.107 ± 0.449
1.554ProTrp: 1.554 ± 0.747
3.107ProTyr: 3.107 ± 0.449
0.0ProXaa: 0.0 ± 0.0
Gln
1.554GlnAla: 1.554 ± 0.747
0.0GlnCys: 0.0 ± 0.0
0.518GlnAsp: 0.518 ± 0.249
1.036GlnGlu: 1.036 ± 0.498
3.625GlnPhe: 3.625 ± 0.2
1.554GlnGly: 1.554 ± 0.747
0.518GlnHis: 0.518 ± 0.249
0.518GlnIle: 0.518 ± 0.249
1.036GlnLys: 1.036 ± 1.445
5.179GlnLeu: 5.179 ± 1.396
1.036GlnMet: 1.036 ± 0.498
0.0GlnAsn: 0.0 ± 0.0
3.107GlnPro: 3.107 ± 1.494
0.518GlnGln: 0.518 ± 0.249
1.036GlnArg: 1.036 ± 0.498
3.107GlnSer: 3.107 ± 0.449
2.589GlnThr: 2.589 ± 1.245
0.518GlnVal: 0.518 ± 0.249
0.0GlnTrp: 0.0 ± 0.0
0.518GlnTyr: 0.518 ± 0.249
0.0GlnXaa: 0.0 ± 0.0
Arg
2.071ArgAla: 2.071 ± 0.996
0.0ArgCys: 0.0 ± 0.0
1.554ArgAsp: 1.554 ± 1.196
1.554ArgGlu: 1.554 ± 0.747
5.179ArgPhe: 5.179 ± 1.396
1.036ArgGly: 1.036 ± 1.445
1.554ArgHis: 1.554 ± 0.747
3.625ArgIle: 3.625 ± 0.2
0.518ArgLys: 0.518 ± 0.249
6.732ArgLeu: 6.732 ± 3.238
1.036ArgMet: 1.036 ± 0.498
1.554ArgAsn: 1.554 ± 0.747
7.768ArgPro: 7.768 ± 0.15
2.071ArgGln: 2.071 ± 0.947
1.554ArgArg: 1.554 ± 0.747
8.804ArgSer: 8.804 ± 2.291
3.625ArgThr: 3.625 ± 1.743
3.625ArgVal: 3.625 ± 2.143
0.0ArgTrp: 0.0 ± 0.0
1.036ArgTyr: 1.036 ± 1.445
0.0ArgXaa: 0.0 ± 0.0
Ser
7.768SerAla: 7.768 ± 0.15
1.036SerCys: 1.036 ± 1.445
5.179SerAsp: 5.179 ± 1.396
4.661SerGlu: 4.661 ± 1.645
5.179SerPhe: 5.179 ± 0.547
4.661SerGly: 4.661 ± 1.645
3.625SerHis: 3.625 ± 1.743
8.286SerIle: 8.286 ± 0.099
5.697SerLys: 5.697 ± 1.147
15.018SerLeu: 15.018 ± 1.393
3.107SerMet: 3.107 ± 1.56
4.661SerAsn: 4.661 ± 5.531
8.804SerPro: 8.804 ± 3.538
3.625SerGln: 3.625 ± 1.743
8.804SerArg: 8.804 ± 0.348
20.197SerSer: 20.197 ± 3.889
7.768SerThr: 7.768 ± 3.736
4.143SerVal: 4.143 ± 0.049
3.625SerTrp: 3.625 ± 1.743
1.036SerTyr: 1.036 ± 0.498
0.0SerXaa: 0.0 ± 0.0
Thr
3.625ThrAla: 3.625 ± 0.2
1.036ThrCys: 1.036 ± 1.445
5.179ThrAsp: 5.179 ± 1.396
1.036ThrGlu: 1.036 ± 0.498
2.589ThrPhe: 2.589 ± 1.245
1.554ThrGly: 1.554 ± 0.747
1.036ThrHis: 1.036 ± 0.498
3.625ThrIle: 3.625 ± 1.743
2.071ThrLys: 2.071 ± 0.996
7.25ThrLeu: 7.25 ± 1.544
0.0ThrMet: 0.0 ± 0.0
2.071ThrAsn: 2.071 ± 0.996
5.179ThrPro: 5.179 ± 0.547
2.589ThrGln: 2.589 ± 0.698
3.625ThrArg: 3.625 ± 0.2
6.214ThrSer: 6.214 ± 2.989
4.143ThrThr: 4.143 ± 1.894
1.554ThrVal: 1.554 ± 1.196
0.518ThrTrp: 0.518 ± 0.249
2.071ThrTyr: 2.071 ± 0.996
0.0ThrXaa: 0.0 ± 0.0
Val
3.107ValAla: 3.107 ± 2.392
1.036ValCys: 1.036 ± 0.498
2.071ValAsp: 2.071 ± 0.996
1.554ValGlu: 1.554 ± 0.747
4.143ValPhe: 4.143 ± 1.992
2.589ValGly: 2.589 ± 0.698
1.036ValHis: 1.036 ± 0.498
2.071ValIle: 2.071 ± 0.947
2.071ValLys: 2.071 ± 2.89
5.697ValLeu: 5.697 ± 3.09
0.518ValMet: 0.518 ± 0.249
3.625ValAsn: 3.625 ± 2.143
4.143ValPro: 4.143 ± 1.894
0.518ValGln: 0.518 ± 0.249
4.143ValArg: 4.143 ± 1.894
4.143ValSer: 4.143 ± 5.78
3.107ValThr: 3.107 ± 1.494
2.071ValVal: 2.071 ± 0.947
0.0ValTrp: 0.0 ± 0.0
2.071ValTyr: 2.071 ± 0.996
0.0ValXaa: 0.0 ± 0.0
Trp
0.518TrpAla: 0.518 ± 0.249
0.518TrpCys: 0.518 ± 0.249
0.0TrpAsp: 0.0 ± 0.0
0.518TrpGlu: 0.518 ± 0.249
0.518TrpPhe: 0.518 ± 0.249
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.518TrpIle: 0.518 ± 1.694
1.036TrpLys: 1.036 ± 0.498
1.036TrpLeu: 1.036 ± 1.445
0.0TrpMet: 0.0 ± 0.0
1.036TrpAsn: 1.036 ± 0.498
0.518TrpPro: 0.518 ± 0.249
0.518TrpGln: 0.518 ± 0.249
1.554TrpArg: 1.554 ± 0.747
2.071TrpSer: 2.071 ± 0.947
2.071TrpThr: 2.071 ± 0.996
0.518TrpVal: 0.518 ± 0.249
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.071TyrAla: 2.071 ± 0.947
1.036TyrCys: 1.036 ± 0.498
1.554TyrAsp: 1.554 ± 0.747
0.518TyrGlu: 0.518 ± 0.249
1.554TyrPhe: 1.554 ± 0.747
0.0TyrGly: 0.0 ± 0.0
1.554TyrHis: 1.554 ± 0.747
3.107TyrIle: 3.107 ± 1.494
0.518TyrLys: 0.518 ± 0.249
3.625TyrLeu: 3.625 ± 1.743
0.518TyrMet: 0.518 ± 0.249
1.554TyrAsn: 1.554 ± 0.747
1.554TyrPro: 1.554 ± 1.196
1.554TyrGln: 1.554 ± 0.747
1.554TyrArg: 1.554 ± 1.196
1.554TyrSer: 1.554 ± 0.747
0.518TyrThr: 0.518 ± 0.249
1.554TyrVal: 1.554 ± 0.747
0.0TyrTrp: 0.0 ± 0.0
1.554TyrTyr: 1.554 ± 0.747
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1932 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski