Amino acid dipepetide frequency for Marinomonas spartinae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.415AlaAla: 7.415 ± 0.104	1.005AlaCys: 1.005 ± 0.033	4.344AlaAsp: 4.344 ± 0.072	4.604AlaGlu: 4.604 ± 0.068	3.769AlaPhe: 3.769 ± 0.058	5.838AlaGly: 5.838 ± 0.088	1.878AlaHis: 1.878 ± 0.041	6.085AlaIle: 6.085 ± 0.069	4.93AlaLys: 4.93 ± 0.061	10.141AlaLeu: 10.141 ± 0.097	2.717AlaMet: 2.717 ± 0.047	3.515AlaAsn: 3.515 ± 0.064	3.0AlaPro: 3.0 ± 0.053	3.696AlaGln: 3.696 ± 0.063	3.731AlaArg: 3.731 ± 0.055	5.751AlaSer: 5.751 ± 0.077	4.409AlaThr: 4.409 ± 0.069	5.471AlaVal: 5.471 ± 0.069	1.033AlaTrp: 1.033 ± 0.031	2.496AlaTyr: 2.496 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.791CysAla: 0.791 ± 0.035	0.158CysCys: 0.158 ± 0.01	0.621CysAsp: 0.621 ± 0.024	0.594CysGlu: 0.594 ± 0.018	0.546CysPhe: 0.546 ± 0.02	0.861CysGly: 0.861 ± 0.025	0.357CysHis: 0.357 ± 0.016	0.613CysIle: 0.613 ± 0.022	0.363CysLys: 0.363 ± 0.019	1.203CysLeu: 1.203 ± 0.029	0.2CysMet: 0.2 ± 0.012	0.284CysAsn: 0.284 ± 0.013	0.447CysPro: 0.447 ± 0.021	0.525CysGln: 0.525 ± 0.024	0.522CysArg: 0.522 ± 0.02	0.653CysSer: 0.653 ± 0.023	0.434CysThr: 0.434 ± 0.017	0.73CysVal: 0.73 ± 0.027	0.131CysTrp: 0.131 ± 0.01	0.364CysTyr: 0.364 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.212AspAla: 4.212 ± 0.065	0.514AspCys: 0.514 ± 0.022	2.951AspAsp: 2.951 ± 0.058	3.587AspGlu: 3.587 ± 0.065	2.299AspPhe: 2.299 ± 0.042	3.571AspGly: 3.571 ± 0.061	1.358AspHis: 1.358 ± 0.034	3.932AspIle: 3.932 ± 0.064	3.115AspLys: 3.115 ± 0.055	5.39AspLeu: 5.39 ± 0.076	1.479AspMet: 1.479 ± 0.036	2.215AspAsn: 2.215 ± 0.047	2.187AspPro: 2.187 ± 0.045	2.234AspGln: 2.234 ± 0.043	2.364AspArg: 2.364 ± 0.045	3.279AspSer: 3.279 ± 0.055	2.731AspThr: 2.731 ± 0.054	3.881AspVal: 3.881 ± 0.058	0.867AspTrp: 0.867 ± 0.029	1.985AspTyr: 1.985 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	5.302GluAla: 5.302 ± 0.07	0.506GluCys: 0.506 ± 0.016	2.842GluAsp: 2.842 ± 0.054	3.971GluGlu: 3.971 ± 0.069	2.153GluPhe: 2.153 ± 0.044	3.546GluGly: 3.546 ± 0.059	1.502GluHis: 1.502 ± 0.034	3.327GluIle: 3.327 ± 0.061	3.794GluLys: 3.794 ± 0.067	6.063GluLeu: 6.063 ± 0.083	1.569GluMet: 1.569 ± 0.033	2.392GluAsn: 2.392 ± 0.049	1.883GluPro: 1.883 ± 0.043	3.37GluGln: 3.37 ± 0.058	3.272GluArg: 3.272 ± 0.052	3.84GluSer: 3.84 ± 0.057	2.943GluThr: 2.943 ± 0.051	3.849GluVal: 3.849 ± 0.055	0.726GluTrp: 0.726 ± 0.024	1.608GluTyr: 1.608 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.527PheAla: 3.527 ± 0.058	0.541PheCys: 0.541 ± 0.018	2.68PheAsp: 2.68 ± 0.041	2.314PheGlu: 2.314 ± 0.045	1.968PhePhe: 1.968 ± 0.052	3.103PheGly: 3.103 ± 0.052	0.969PheHis: 0.969 ± 0.028	2.82PheIle: 2.82 ± 0.047	1.923PheLys: 1.923 ± 0.039	3.857PheLeu: 3.857 ± 0.075	1.029PheMet: 1.029 ± 0.033	1.813PheAsn: 1.813 ± 0.039	1.559PhePro: 1.559 ± 0.037	1.397PheGln: 1.397 ± 0.032	1.607PheArg: 1.607 ± 0.037	3.466PheSer: 3.466 ± 0.056	2.289PheThr: 2.289 ± 0.043	2.847PheVal: 2.847 ± 0.052	0.552PheTrp: 0.552 ± 0.021	1.413PheTyr: 1.413 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	5.39GlyAla: 5.39 ± 0.073	0.827GlyCys: 0.827 ± 0.024	3.46GlyAsp: 3.46 ± 0.062	3.91GlyGlu: 3.91 ± 0.061	3.359GlyPhe: 3.359 ± 0.058	4.772GlyGly: 4.772 ± 0.078	1.662GlyHis: 1.662 ± 0.034	4.751GlyIle: 4.751 ± 0.066	3.992GlyLys: 3.992 ± 0.053	7.145GlyLeu: 7.145 ± 0.081	2.077GlyMet: 2.077 ± 0.041	2.489GlyAsn: 2.489 ± 0.068	1.875GlyPro: 1.875 ± 0.04	2.872GlyGln: 2.872 ± 0.046	3.237GlyArg: 3.237 ± 0.051	4.244GlySer: 4.244 ± 0.067	3.335GlyThr: 3.335 ± 0.084	5.37GlyVal: 5.37 ± 0.077	0.95GlyTrp: 0.95 ± 0.03	2.51GlyTyr: 2.51 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	1.814HisAla: 1.814 ± 0.039	0.326HisCys: 0.326 ± 0.017	1.208HisAsp: 1.208 ± 0.037	1.195HisGlu: 1.195 ± 0.03	1.241HisPhe: 1.241 ± 0.035	1.584HisGly: 1.584 ± 0.034	0.804HisHis: 0.804 ± 0.028	1.619HisIle: 1.619 ± 0.031	1.109HisLys: 1.109 ± 0.028	2.597HisLeu: 2.597 ± 0.05	0.571HisMet: 0.571 ± 0.019	0.906HisAsn: 0.906 ± 0.025	1.359HisPro: 1.359 ± 0.034	1.193HisGln: 1.193 ± 0.032	1.119HisArg: 1.119 ± 0.03	1.615HisSer: 1.615 ± 0.037	1.197HisThr: 1.197 ± 0.028	1.378HisVal: 1.378 ± 0.034	0.411HisTrp: 0.411 ± 0.018	1.005HisTyr: 1.005 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.343IleAla: 6.343 ± 0.08	0.713IleCys: 0.713 ± 0.025	4.046IleAsp: 4.046 ± 0.059	4.277IleGlu: 4.277 ± 0.062	2.247IlePhe: 2.247 ± 0.053	4.848IleGly: 4.848 ± 0.071	1.493IleHis: 1.493 ± 0.04	3.808IleIle: 3.808 ± 0.066	3.507IleLys: 3.507 ± 0.057	5.768IleLeu: 5.768 ± 0.082	1.44IleMet: 1.44 ± 0.032	2.907IleAsn: 2.907 ± 0.049	2.759IlePro: 2.759 ± 0.048	2.481IleGln: 2.481 ± 0.044	3.093IleArg: 3.093 ± 0.049	4.503IleSer: 4.503 ± 0.059	3.606IleThr: 3.606 ± 0.065	4.206IleVal: 4.206 ± 0.065	0.676IleTrp: 0.676 ± 0.023	1.687IleTyr: 1.687 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	5.201LysAla: 5.201 ± 0.072	0.313LysCys: 0.313 ± 0.016	3.044LysAsp: 3.044 ± 0.045	3.763LysGlu: 3.763 ± 0.061	1.305LysPhe: 1.305 ± 0.033	3.709LysGly: 3.709 ± 0.052	1.389LysHis: 1.389 ± 0.034	3.025LysIle: 3.025 ± 0.051	3.367LysLys: 3.367 ± 0.064	4.787LysLeu: 4.787 ± 0.065	1.465LysMet: 1.465 ± 0.034	2.424LysAsn: 2.424 ± 0.043	2.252LysPro: 2.252 ± 0.045	2.899LysGln: 2.899 ± 0.048	2.97LysArg: 2.97 ± 0.049	3.309LysSer: 3.309 ± 0.055	3.115LysThr: 3.115 ± 0.053	3.852LysVal: 3.852 ± 0.055	0.596LysTrp: 0.596 ± 0.019	1.265LysTyr: 1.265 ± 0.034	0.0LysXaa: 0.0 ± 0.0
Leu	9.812LeuAla: 9.812 ± 0.101	1.149LeuCys: 1.149 ± 0.032	5.724LeuAsp: 5.724 ± 0.072	6.01LeuGlu: 6.01 ± 0.089	4.355LeuPhe: 4.355 ± 0.075	7.083LeuGly: 7.083 ± 0.078	2.145LeuHis: 2.145 ± 0.044	6.6LeuIle: 6.6 ± 0.086	5.638LeuLys: 5.638 ± 0.076	10.807LeuLeu: 10.807 ± 0.136	2.778LeuMet: 2.778 ± 0.046	4.432LeuAsn: 4.432 ± 0.061	4.967LeuPro: 4.967 ± 0.074	3.688LeuGln: 3.688 ± 0.057	4.323LeuArg: 4.323 ± 0.058	8.583LeuSer: 8.583 ± 0.081	6.182LeuThr: 6.182 ± 0.1	7.123LeuVal: 7.123 ± 0.075	1.109LeuTrp: 1.109 ± 0.029	2.744LeuTyr: 2.744 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.637MetAla: 2.637 ± 0.052	0.2MetCys: 0.2 ± 0.013	1.384MetAsp: 1.384 ± 0.032	1.273MetGlu: 1.273 ± 0.027	0.87MetPhe: 0.87 ± 0.032	1.832MetGly: 1.832 ± 0.033	0.487MetHis: 0.487 ± 0.018	1.661MetIle: 1.661 ± 0.04	1.555MetLys: 1.555 ± 0.036	2.748MetLeu: 2.748 ± 0.054	0.776MetMet: 0.776 ± 0.025	1.114MetAsn: 1.114 ± 0.032	1.293MetPro: 1.293 ± 0.033	1.071MetGln: 1.071 ± 0.028	1.22MetArg: 1.22 ± 0.033	2.218MetSer: 2.218 ± 0.043	1.782MetThr: 1.782 ± 0.035	1.815MetVal: 1.815 ± 0.042	0.227MetTrp: 0.227 ± 0.013	0.525MetTyr: 0.525 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.392AsnAla: 3.392 ± 0.072	0.354AsnCys: 0.354 ± 0.017	2.259AsnAsp: 2.259 ± 0.049	2.289AsnGlu: 2.289 ± 0.044	1.432AsnPhe: 1.432 ± 0.036	3.019AsnGly: 3.019 ± 0.075	1.077AsnHis: 1.077 ± 0.03	2.727AsnIle: 2.727 ± 0.045	2.404AsnLys: 2.404 ± 0.042	3.833AsnLeu: 3.833 ± 0.06	1.059AsnMet: 1.059 ± 0.025	1.912AsnAsn: 1.912 ± 0.059	2.019AsnPro: 2.019 ± 0.04	1.926AsnGln: 1.926 ± 0.046	1.908AsnArg: 1.908 ± 0.04	2.431AsnSer: 2.431 ± 0.055	2.541AsnThr: 2.541 ± 0.071	2.595AsnVal: 2.595 ± 0.047	0.604AsnTrp: 0.604 ± 0.022	1.217AsnTyr: 1.217 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	3.161ProAla: 3.161 ± 0.055	0.33ProCys: 0.33 ± 0.021	2.436ProAsp: 2.436 ± 0.043	3.027ProGlu: 3.027 ± 0.049	1.846ProPhe: 1.846 ± 0.042	2.273ProGly: 2.273 ± 0.044	1.009ProHis: 1.009 ± 0.029	2.788ProIle: 2.788 ± 0.05	2.377ProLys: 2.377 ± 0.051	4.084ProLeu: 4.084 ± 0.064	1.108ProMet: 1.108 ± 0.031	1.939ProAsn: 1.939 ± 0.041	1.283ProPro: 1.283 ± 0.034	1.507ProGln: 1.507 ± 0.038	1.4ProArg: 1.4 ± 0.033	2.903ProSer: 2.903 ± 0.044	2.284ProThr: 2.284 ± 0.043	3.027ProVal: 3.027 ± 0.052	0.539ProTrp: 0.539 ± 0.022	1.353ProTyr: 1.353 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	4.43GlnAla: 4.43 ± 0.067	0.421GlnCys: 0.421 ± 0.027	2.092GlnAsp: 2.092 ± 0.039	2.449GlnGlu: 2.449 ± 0.044	1.577GlnPhe: 1.577 ± 0.036	2.962GlnGly: 2.962 ± 0.056	1.21GlnHis: 1.21 ± 0.034	2.489GlnIle: 2.489 ± 0.044	2.28GlnLys: 2.28 ± 0.042	4.663GlnLeu: 4.663 ± 0.068	1.055GlnMet: 1.055 ± 0.027	1.711GlnAsn: 1.711 ± 0.044	1.686GlnPro: 1.686 ± 0.041	2.57GlnGln: 2.57 ± 0.065	2.204GlnArg: 2.204 ± 0.044	2.936GlnSer: 2.936 ± 0.049	2.481GlnThr: 2.481 ± 0.05	3.171GlnVal: 3.171 ± 0.046	0.668GlnTrp: 0.668 ± 0.024	1.334GlnTyr: 1.334 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	3.503ArgAla: 3.503 ± 0.055	0.485ArgCys: 0.485 ± 0.019	2.314ArgAsp: 2.314 ± 0.044	2.705ArgGlu: 2.705 ± 0.054	2.35ArgPhe: 2.35 ± 0.043	2.603ArgGly: 2.603 ± 0.049	1.311ArgHis: 1.311 ± 0.032	3.133ArgIle: 3.133 ± 0.058	2.28ArgLys: 2.28 ± 0.043	5.414ArgLeu: 5.414 ± 0.074	1.241ArgMet: 1.241 ± 0.032	1.72ArgAsn: 1.72 ± 0.037	1.815ArgPro: 1.815 ± 0.038	2.364ArgGln: 2.364 ± 0.048	2.485ArgArg: 2.485 ± 0.051	2.782ArgSer: 2.782 ± 0.048	2.093ArgThr: 2.093 ± 0.039	3.17ArgVal: 3.17 ± 0.046	0.633ArgTrp: 0.633 ± 0.02	1.791ArgTyr: 1.791 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.413SerAla: 5.413 ± 0.076	0.634SerCys: 0.634 ± 0.022	3.735SerAsp: 3.735 ± 0.064	3.741SerGlu: 3.741 ± 0.056	2.98SerPhe: 2.98 ± 0.048	4.936SerGly: 4.936 ± 0.077	1.746SerHis: 1.746 ± 0.039	4.57SerIle: 4.57 ± 0.064	3.525SerLys: 3.525 ± 0.061	7.857SerLeu: 7.857 ± 0.085	1.883SerMet: 1.883 ± 0.039	2.761SerAsn: 2.761 ± 0.053	2.749SerPro: 2.749 ± 0.05	3.149SerGln: 3.149 ± 0.056	3.051SerArg: 3.051 ± 0.048	5.045SerSer: 5.045 ± 0.081	3.506SerThr: 3.506 ± 0.08	4.84SerVal: 4.84 ± 0.065	0.87SerTrp: 0.87 ± 0.028	2.066SerTyr: 2.066 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	4.269ThrAla: 4.269 ± 0.082	0.536ThrCys: 0.536 ± 0.021	2.818ThrAsp: 2.818 ± 0.055	2.712ThrGlu: 2.712 ± 0.048	2.212ThrPhe: 2.212 ± 0.046	3.953ThrGly: 3.953 ± 0.079	1.332ThrHis: 1.332 ± 0.03	3.436ThrIle: 3.436 ± 0.078	2.515ThrLys: 2.515 ± 0.044	6.69ThrLeu: 6.69 ± 0.087	1.22ThrMet: 1.22 ± 0.035	2.13ThrAsn: 2.13 ± 0.077	2.962ThrPro: 2.962 ± 0.041	2.531ThrGln: 2.531 ± 0.052	2.21ThrArg: 2.21 ± 0.041	3.559ThrSer: 3.559 ± 0.063	2.941ThrThr: 2.941 ± 0.061	3.539ThrVal: 3.539 ± 0.069	0.646ThrTrp: 0.646 ± 0.023	1.481ThrTyr: 1.481 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	6.15ValAla: 6.15 ± 0.074	0.814ValCys: 0.814 ± 0.027	3.978ValAsp: 3.978 ± 0.061	3.972ValGlu: 3.972 ± 0.058	3.041ValPhe: 3.041 ± 0.053	4.795ValGly: 4.795 ± 0.067	1.299ValHis: 1.299 ± 0.032	4.657ValIle: 4.657 ± 0.057	3.456ValLys: 3.456 ± 0.054	6.973ValLeu: 6.973 ± 0.082	2.049ValMet: 2.049 ± 0.04	2.828ValAsn: 2.828 ± 0.05	2.667ValPro: 2.667 ± 0.039	2.215ValGln: 2.215 ± 0.041	2.987ValArg: 2.987 ± 0.056	5.142ValSer: 5.142 ± 0.075	3.909ValThr: 3.909 ± 0.069	5.252ValVal: 5.252 ± 0.08	0.814ValTrp: 0.814 ± 0.026	1.845ValTyr: 1.845 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	0.829TrpAla: 0.829 ± 0.024	0.158TrpCys: 0.158 ± 0.011	0.558TrpAsp: 0.558 ± 0.022	0.511TrpGlu: 0.511 ± 0.018	0.643TrpPhe: 0.643 ± 0.023	0.818TrpGly: 0.818 ± 0.023	0.386TrpHis: 0.386 ± 0.018	0.707TrpIle: 0.707 ± 0.02	0.528TrpLys: 0.528 ± 0.021	1.782TrpLeu: 1.782 ± 0.045	0.366TrpMet: 0.366 ± 0.017	0.441TrpAsn: 0.441 ± 0.018	0.516TrpPro: 0.516 ± 0.02	0.882TrpGln: 0.882 ± 0.027	0.745TrpArg: 0.745 ± 0.024	0.827TrpSer: 0.827 ± 0.026	0.504TrpThr: 0.504 ± 0.021	0.951TrpVal: 0.951 ± 0.033	0.194TrpTrp: 0.194 ± 0.013	0.365TrpTyr: 0.365 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.236TyrAla: 2.236 ± 0.051	0.412TyrCys: 0.412 ± 0.017	1.658TyrAsp: 1.658 ± 0.038	1.557TyrGlu: 1.557 ± 0.032	1.48TyrPhe: 1.48 ± 0.039	2.12TyrGly: 2.12 ± 0.04	0.833TyrHis: 0.833 ± 0.027	1.66TyrIle: 1.66 ± 0.035	1.39TyrLys: 1.39 ± 0.035	3.449TyrLeu: 3.449 ± 0.053	0.604TyrMet: 0.604 ± 0.024	1.066TyrAsn: 1.066 ± 0.029	1.4TyrPro: 1.4 ± 0.034	1.82TyrGln: 1.82 ± 0.04	1.746TyrArg: 1.746 ± 0.037	1.972TyrSer: 1.972 ± 0.039	1.411TyrThr: 1.411 ± 0.035	1.776TyrVal: 1.776 ± 0.037	0.466TyrTrp: 0.466 ± 0.019	1.007TyrTyr: 1.007 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4312 proteins (1376740 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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