Amino acid dipepetide frequency for Desertiactinospora gelatinilytica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.07AlaAla: 22.07 ± 0.159	1.144AlaCys: 1.144 ± 0.024	8.074AlaAsp: 8.074 ± 0.062	9.008AlaGlu: 9.008 ± 0.08	3.644AlaPhe: 3.644 ± 0.038	13.975AlaGly: 13.975 ± 0.09	2.836AlaHis: 2.836 ± 0.039	4.528AlaIle: 4.528 ± 0.045	2.761AlaLys: 2.761 ± 0.045	14.641AlaLeu: 14.641 ± 0.103	2.789AlaMet: 2.789 ± 0.036	1.901AlaAsn: 1.901 ± 0.028	6.4AlaPro: 6.4 ± 0.07	3.374AlaGln: 3.374 ± 0.044	11.086AlaArg: 11.086 ± 0.091	5.229AlaSer: 5.229 ± 0.049	6.923AlaThr: 6.923 ± 0.065	11.791AlaVal: 11.791 ± 0.094	1.978AlaTrp: 1.978 ± 0.033	2.687AlaTyr: 2.687 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.127CysAla: 1.127 ± 0.023	0.094CysCys: 0.094 ± 0.006	0.548CysAsp: 0.548 ± 0.016	0.436CysGlu: 0.436 ± 0.012	0.218CysPhe: 0.218 ± 0.012	0.995CysGly: 0.995 ± 0.022	0.211CysHis: 0.211 ± 0.009	0.139CysIle: 0.139 ± 0.008	0.101CysLys: 0.101 ± 0.006	0.807CysLeu: 0.807 ± 0.018	0.134CysMet: 0.134 ± 0.009	0.129CysAsn: 0.129 ± 0.008	0.543CysPro: 0.543 ± 0.016	0.172CysGln: 0.172 ± 0.008	0.697CysArg: 0.697 ± 0.018	0.431CysSer: 0.431 ± 0.014	0.456CysThr: 0.456 ± 0.014	0.697CysVal: 0.697 ± 0.016	0.113CysTrp: 0.113 ± 0.008	0.179CysTyr: 0.179 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.935AspAla: 6.935 ± 0.065	0.365AspCys: 0.365 ± 0.012	3.767AspAsp: 3.767 ± 0.045	3.558AspGlu: 3.558 ± 0.042	1.573AspPhe: 1.573 ± 0.025	5.805AspGly: 5.805 ± 0.063	1.461AspHis: 1.461 ± 0.027	1.99AspIle: 1.99 ± 0.033	1.007AspLys: 1.007 ± 0.026	6.618AspLeu: 6.618 ± 0.057	0.852AspMet: 0.852 ± 0.017	0.858AspAsn: 0.858 ± 0.021	4.716AspPro: 4.716 ± 0.053	1.495AspGln: 1.495 ± 0.028	5.121AspArg: 5.121 ± 0.051	2.081AspSer: 2.081 ± 0.033	2.63AspThr: 2.63 ± 0.028	4.724AspVal: 4.724 ± 0.042	0.863AspTrp: 0.863 ± 0.022	1.171AspTyr: 1.171 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	6.906GluAla: 6.906 ± 0.071	0.407GluCys: 0.407 ± 0.013	2.408GluAsp: 2.408 ± 0.03	3.435GluGlu: 3.435 ± 0.047	1.494GluPhe: 1.494 ± 0.027	4.064GluGly: 4.064 ± 0.044	1.575GluHis: 1.575 ± 0.025	2.669GluIle: 2.669 ± 0.04	1.139GluLys: 1.139 ± 0.027	6.652GluLeu: 6.652 ± 0.063	1.005GluMet: 1.005 ± 0.024	0.866GluAsn: 0.866 ± 0.024	3.514GluPro: 3.514 ± 0.051	1.992GluGln: 1.992 ± 0.037	5.988GluArg: 5.988 ± 0.06	2.523GluSer: 2.523 ± 0.033	2.725GluThr: 2.725 ± 0.037	4.765GluVal: 4.765 ± 0.051	0.89GluTrp: 0.89 ± 0.019	1.138GluTyr: 1.138 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	3.975PheAla: 3.975 ± 0.044	0.279PheCys: 0.279 ± 0.011	1.983PheAsp: 1.983 ± 0.029	1.407PheGlu: 1.407 ± 0.03	0.863PhePhe: 0.863 ± 0.021	3.084PheGly: 3.084 ± 0.04	0.626PheHis: 0.626 ± 0.017	0.829PheIle: 0.829 ± 0.02	0.483PheLys: 0.483 ± 0.017	2.5PheLeu: 2.5 ± 0.036	0.433PheMet: 0.433 ± 0.015	0.568PheAsn: 0.568 ± 0.017	1.399PhePro: 1.399 ± 0.027	0.693PheGln: 0.693 ± 0.017	1.858PheArg: 1.858 ± 0.03	1.405PheSer: 1.405 ± 0.027	1.903PheThr: 1.903 ± 0.034	2.269PheVal: 2.269 ± 0.035	0.422PheTrp: 0.422 ± 0.013	0.607PheTyr: 0.607 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	10.431GlyAla: 10.431 ± 0.084	0.867GlyCys: 0.867 ± 0.02	5.441GlyAsp: 5.441 ± 0.059	5.658GlyGlu: 5.658 ± 0.054	2.951GlyPhe: 2.951 ± 0.043	9.191GlyGly: 9.191 ± 0.086	2.496GlyHis: 2.496 ± 0.038	3.42GlyIle: 3.42 ± 0.043	2.266GlyLys: 2.266 ± 0.041	9.876GlyLeu: 9.876 ± 0.08	2.198GlyMet: 2.198 ± 0.028	1.594GlyAsn: 1.594 ± 0.028	5.431GlyPro: 5.431 ± 0.055	2.563GlyGln: 2.563 ± 0.041	8.661GlyArg: 8.661 ± 0.066	4.654GlySer: 4.654 ± 0.049	5.553GlyThr: 5.553 ± 0.058	8.021GlyVal: 8.021 ± 0.063	1.714GlyTrp: 1.714 ± 0.028	2.306GlyTyr: 2.306 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	2.772HisAla: 2.772 ± 0.037	0.225HisCys: 0.225 ± 0.01	1.446HisAsp: 1.446 ± 0.024	1.226HisGlu: 1.226 ± 0.022	0.58HisPhe: 0.58 ± 0.016	2.328HisGly: 2.328 ± 0.032	0.649HisHis: 0.649 ± 0.02	0.762HisIle: 0.762 ± 0.017	0.31HisLys: 0.31 ± 0.014	2.531HisLeu: 2.531 ± 0.035	0.359HisMet: 0.359 ± 0.014	0.389HisAsn: 0.389 ± 0.013	1.777HisPro: 1.777 ± 0.029	0.621HisGln: 0.621 ± 0.016	2.136HisArg: 2.136 ± 0.032	0.906HisSer: 0.906 ± 0.02	1.178HisThr: 1.178 ± 0.026	1.759HisVal: 1.759 ± 0.031	0.337HisTrp: 0.337 ± 0.012	0.474HisTyr: 0.474 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	5.597IleAla: 5.597 ± 0.047	0.352IleCys: 0.352 ± 0.012	2.712IleAsp: 2.712 ± 0.033	2.362IleGlu: 2.362 ± 0.034	0.921IlePhe: 0.921 ± 0.022	4.055IleGly: 4.055 ± 0.046	0.672IleHis: 0.672 ± 0.018	1.211IleIle: 1.211 ± 0.028	0.832IleLys: 0.832 ± 0.02	2.753IleLeu: 2.753 ± 0.037	0.594IleMet: 0.594 ± 0.018	0.797IleAsn: 0.797 ± 0.021	1.985IlePro: 1.985 ± 0.028	0.756IleGln: 0.756 ± 0.019	2.67IleArg: 2.67 ± 0.038	1.942IleSer: 1.942 ± 0.031	2.572IleThr: 2.572 ± 0.034	3.304IleVal: 3.304 ± 0.048	0.461IleTrp: 0.461 ± 0.014	0.685IleTyr: 0.685 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	2.504LysAla: 2.504 ± 0.04	0.115LysCys: 0.115 ± 0.007	1.085LysAsp: 1.085 ± 0.027	1.094LysGlu: 1.094 ± 0.025	0.401LysPhe: 0.401 ± 0.015	1.676LysGly: 1.676 ± 0.034	0.397LysHis: 0.397 ± 0.012	0.968LysIle: 0.968 ± 0.024	0.602LysLys: 0.602 ± 0.022	1.832LysLeu: 1.832 ± 0.027	0.355LysMet: 0.355 ± 0.013	0.438LysAsn: 0.438 ± 0.019	1.237LysPro: 1.237 ± 0.027	0.551LysGln: 0.551 ± 0.02	1.444LysArg: 1.444 ± 0.024	1.041LysSer: 1.041 ± 0.027	1.105LysThr: 1.105 ± 0.025	1.858LysVal: 1.858 ± 0.032	0.228LysTrp: 0.228 ± 0.011	0.423LysTyr: 0.423 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	16.256LeuAla: 16.256 ± 0.125	0.822LeuCys: 0.822 ± 0.021	6.481LeuAsp: 6.481 ± 0.059	4.344LeuGlu: 4.344 ± 0.041	2.553LeuPhe: 2.553 ± 0.042	9.434LeuGly: 9.434 ± 0.08	2.159LeuHis: 2.159 ± 0.032	4.141LeuIle: 4.141 ± 0.051	1.73LeuLys: 1.73 ± 0.033	11.143LeuLeu: 11.143 ± 0.092	1.678LeuMet: 1.678 ± 0.027	1.706LeuAsn: 1.706 ± 0.031	6.521LeuPro: 6.521 ± 0.058	1.894LeuGln: 1.894 ± 0.033	9.368LeuArg: 9.368 ± 0.078	5.526LeuSer: 5.526 ± 0.05	6.844LeuThr: 6.844 ± 0.06	8.716LeuVal: 8.716 ± 0.081	1.308LeuTrp: 1.308 ± 0.025	1.835LeuTyr: 1.835 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	2.537MetAla: 2.537 ± 0.039	0.142MetCys: 0.142 ± 0.008	0.923MetAsp: 0.923 ± 0.021	0.83MetGlu: 0.83 ± 0.017	0.536MetPhe: 0.536 ± 0.016	1.375MetGly: 1.375 ± 0.027	0.333MetHis: 0.333 ± 0.011	0.892MetIle: 0.892 ± 0.019	0.38MetLys: 0.38 ± 0.014	1.992MetLeu: 1.992 ± 0.032	0.35MetMet: 0.35 ± 0.012	0.45MetAsn: 0.45 ± 0.012	1.258MetPro: 1.258 ± 0.021	0.398MetGln: 0.398 ± 0.015	1.733MetArg: 1.733 ± 0.025	1.367MetSer: 1.367 ± 0.026	1.495MetThr: 1.495 ± 0.024	1.442MetVal: 1.442 ± 0.024	0.237MetTrp: 0.237 ± 0.011	0.333MetTyr: 0.333 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.163AsnAla: 2.163 ± 0.034	0.172AsnCys: 0.172 ± 0.008	0.892AsnAsp: 0.892 ± 0.021	0.789AsnGlu: 0.789 ± 0.021	0.438AsnPhe: 0.438 ± 0.015	1.748AsnGly: 1.748 ± 0.032	0.377AsnHis: 0.377 ± 0.013	0.619AsnIle: 0.619 ± 0.017	0.35AsnLys: 0.35 ± 0.015	1.745AsnLeu: 1.745 ± 0.034	0.295AsnMet: 0.295 ± 0.012	0.364AsnAsn: 0.364 ± 0.015	1.269AsnPro: 1.269 ± 0.022	0.462AsnGln: 0.462 ± 0.014	1.241AsnArg: 1.241 ± 0.024	0.74AsnSer: 0.74 ± 0.018	0.943AsnThr: 0.943 ± 0.023	1.436AsnVal: 1.436 ± 0.029	0.269AsnTrp: 0.269 ± 0.009	0.381AsnTyr: 0.381 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	8.868ProAla: 8.868 ± 0.07	0.384ProCys: 0.384 ± 0.014	4.227ProAsp: 4.227 ± 0.047	4.139ProGlu: 4.139 ± 0.048	1.567ProPhe: 1.567 ± 0.028	7.261ProGly: 7.261 ± 0.063	1.346ProHis: 1.346 ± 0.027	1.958ProIle: 1.958 ± 0.03	1.159ProLys: 1.159 ± 0.023	5.403ProLeu: 5.403 ± 0.05	1.165ProMet: 1.165 ± 0.02	0.89ProAsn: 0.89 ± 0.019	4.142ProPro: 4.142 ± 0.053	1.61ProGln: 1.61 ± 0.028	4.269ProArg: 4.269 ± 0.045	2.948ProSer: 2.948 ± 0.036	2.842ProThr: 2.842 ± 0.04	5.259ProVal: 5.259 ± 0.059	0.93ProTrp: 0.93 ± 0.019	1.469ProTyr: 1.469 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.897GlnAla: 3.897 ± 0.045	0.159GlnCys: 0.159 ± 0.008	1.165GlnAsp: 1.165 ± 0.022	1.358GlnGlu: 1.358 ± 0.023	0.581GlnPhe: 0.581 ± 0.016	2.139GlnGly: 2.139 ± 0.038	0.53GlnHis: 0.53 ± 0.013	1.213GlnIle: 1.213 ± 0.023	0.493GlnLys: 0.493 ± 0.016	2.215GlnLeu: 2.215 ± 0.036	0.501GlnMet: 0.501 ± 0.014	0.455GlnAsn: 0.455 ± 0.016	1.462GlnPro: 1.462 ± 0.029	0.93GlnGln: 0.93 ± 0.035	2.403GlnArg: 2.403 ± 0.039	1.089GlnSer: 1.089 ± 0.024	1.206GlnThr: 1.206 ± 0.021	2.561GlnVal: 2.561 ± 0.032	0.436GlnTrp: 0.436 ± 0.013	0.491GlnTyr: 0.491 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	10.74ArgAla: 10.74 ± 0.083	0.692ArgCys: 0.692 ± 0.019	4.632ArgAsp: 4.632 ± 0.052	5.037ArgGlu: 5.037 ± 0.054	2.587ArgPhe: 2.587 ± 0.034	6.313ArgGly: 6.313 ± 0.056	2.341ArgHis: 2.341 ± 0.034	3.334ArgIle: 3.334 ± 0.036	1.597ArgLys: 1.597 ± 0.028	10.049ArgLeu: 10.049 ± 0.081	2.033ArgMet: 2.033 ± 0.031	1.345ArgAsn: 1.345 ± 0.028	5.578ArgPro: 5.578 ± 0.059	2.409ArgGln: 2.409 ± 0.025	8.972ArgArg: 8.972 ± 0.097	4.011ArgSer: 4.011 ± 0.044	4.716ArgThr: 4.716 ± 0.044	6.555ArgVal: 6.555 ± 0.045	1.498ArgTrp: 1.498 ± 0.027	1.93ArgTyr: 1.93 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	6.333SerAla: 6.333 ± 0.052	0.387SerCys: 0.387 ± 0.014	2.397SerAsp: 2.397 ± 0.035	2.202SerGlu: 2.202 ± 0.032	1.462SerPhe: 1.462 ± 0.026	5.698SerGly: 5.698 ± 0.058	0.96SerHis: 0.96 ± 0.023	1.724SerIle: 1.724 ± 0.032	0.866SerLys: 0.866 ± 0.019	4.48SerLeu: 4.48 ± 0.05	1.105SerMet: 1.105 ± 0.024	0.72SerAsn: 0.72 ± 0.02	3.22SerPro: 3.22 ± 0.04	1.092SerGln: 1.092 ± 0.026	3.753SerArg: 3.753 ± 0.041	2.381SerSer: 2.381 ± 0.042	2.574SerThr: 2.574 ± 0.038	3.939SerVal: 3.939 ± 0.041	0.874SerTrp: 0.874 ± 0.019	1.12SerTyr: 1.12 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	7.947ThrAla: 7.947 ± 0.067	0.477ThrCys: 0.477 ± 0.015	2.954ThrAsp: 2.954 ± 0.034	2.81ThrGlu: 2.81 ± 0.038	1.637ThrPhe: 1.637 ± 0.031	6.458ThrGly: 6.458 ± 0.055	1.119ThrHis: 1.119 ± 0.021	2.092ThrIle: 2.092 ± 0.031	0.988ThrLys: 0.988 ± 0.026	5.655ThrLeu: 5.655 ± 0.056	1.135ThrMet: 1.135 ± 0.021	0.83ThrAsn: 0.83 ± 0.022	3.951ThrPro: 3.951 ± 0.046	1.156ThrGln: 1.156 ± 0.024	4.02ThrArg: 4.02 ± 0.043	2.779ThrSer: 2.779 ± 0.036	3.42ThrThr: 3.42 ± 0.048	5.343ThrVal: 5.343 ± 0.059	0.892ThrTrp: 0.892 ± 0.02	1.227ThrTyr: 1.227 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	11.52ValAla: 11.52 ± 0.086	0.769ValCys: 0.769 ± 0.02	4.248ValAsp: 4.248 ± 0.045	4.611ValGlu: 4.611 ± 0.047	2.433ValPhe: 2.433 ± 0.041	6.39ValGly: 6.39 ± 0.052	1.819ValHis: 1.819 ± 0.028	3.534ValIle: 3.534 ± 0.044	1.614ValLys: 1.614 ± 0.031	9.508ValLeu: 9.508 ± 0.081	1.461ValMet: 1.461 ± 0.027	1.632ValAsn: 1.632 ± 0.027	5.409ValPro: 5.409 ± 0.049	1.955ValGln: 1.955 ± 0.031	7.444ValArg: 7.444 ± 0.068	4.335ValSer: 4.335 ± 0.053	5.709ValThr: 5.709 ± 0.05	7.884ValVal: 7.884 ± 0.076	1.118ValTrp: 1.118 ± 0.023	1.62ValTyr: 1.62 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.662TrpAla: 1.662 ± 0.032	0.171TrpCys: 0.171 ± 0.008	0.798TrpAsp: 0.798 ± 0.019	0.747TrpGlu: 0.747 ± 0.018	0.491TrpPhe: 0.491 ± 0.017	1.021TrpGly: 1.021 ± 0.024	0.4TrpHis: 0.4 ± 0.013	0.599TrpIle: 0.599 ± 0.017	0.335TrpLys: 0.335 ± 0.014	1.807TrpLeu: 1.807 ± 0.028	0.296TrpMet: 0.296 ± 0.011	0.375TrpAsn: 0.375 ± 0.013	0.878TrpPro: 0.878 ± 0.021	0.524TrpGln: 0.524 ± 0.017	1.545TrpArg: 1.545 ± 0.03	0.926TrpSer: 0.926 ± 0.02	0.954TrpThr: 0.954 ± 0.022	1.025TrpVal: 1.025 ± 0.022	0.356TrpTrp: 0.356 ± 0.013	0.351TrpTyr: 0.351 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.597TyrAla: 2.597 ± 0.035	0.205TyrCys: 0.205 ± 0.01	1.411TyrAsp: 1.411 ± 0.032	1.104TyrGlu: 1.104 ± 0.025	0.656TyrPhe: 0.656 ± 0.017	2.284TyrGly: 2.284 ± 0.031	0.458TyrHis: 0.458 ± 0.015	0.611TyrIle: 0.611 ± 0.017	0.341TyrLys: 0.341 ± 0.012	2.254TyrLeu: 2.254 ± 0.036	0.263TyrMet: 0.263 ± 0.011	0.385TyrAsn: 0.385 ± 0.015	1.146TyrPro: 1.146 ± 0.026	0.635TyrGln: 0.635 ± 0.017	1.96TyrArg: 1.96 ± 0.033	0.975TyrSer: 0.975 ± 0.022	1.143TyrThr: 1.143 ± 0.029	1.666TyrVal: 1.666 ± 0.03	0.337TyrTrp: 0.337 ± 0.014	0.435TyrTyr: 0.435 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7511 proteins (2234133 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---