Amino acid dipepetide frequency for Filimonas effusa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.049AlaAla: 9.049 ± 0.1
0.768AlaCys: 0.768 ± 0.021
4.371AlaAsp: 4.371 ± 0.052
4.344AlaGlu: 4.344 ± 0.057
3.806AlaPhe: 3.806 ± 0.048
7.141AlaGly: 7.141 ± 0.083
1.361AlaHis: 1.361 ± 0.03
5.448AlaIle: 5.448 ± 0.061
4.1AlaLys: 4.1 ± 0.056
7.551AlaLeu: 7.551 ± 0.085
1.746AlaMet: 1.746 ± 0.033
4.003AlaAsn: 4.003 ± 0.056
2.958AlaPro: 2.958 ± 0.041
3.197AlaGln: 3.197 ± 0.042
3.325AlaArg: 3.325 ± 0.044
5.378AlaSer: 5.378 ± 0.074
5.017AlaThr: 5.017 ± 0.087
5.736AlaVal: 5.736 ± 0.067
1.004AlaTrp: 1.004 ± 0.025
3.197AlaTyr: 3.197 ± 0.043
0.0AlaXaa: 0.0 ± 0.0
Cys
0.559CysAla: 0.559 ± 0.02
0.156CysCys: 0.156 ± 0.008
0.402CysAsp: 0.402 ± 0.016
0.398CysGlu: 0.398 ± 0.018
0.528CysPhe: 0.528 ± 0.018
0.636CysGly: 0.636 ± 0.021
0.199CysHis: 0.199 ± 0.012
0.669CysIle: 0.669 ± 0.02
0.5CysLys: 0.5 ± 0.019
0.853CysLeu: 0.853 ± 0.023
0.215CysMet: 0.215 ± 0.011
0.433CysAsn: 0.433 ± 0.016
0.326CysPro: 0.326 ± 0.015
0.246CysGln: 0.246 ± 0.011
0.395CysArg: 0.395 ± 0.015
0.601CysSer: 0.601 ± 0.023
0.525CysThr: 0.525 ± 0.021
0.497CysVal: 0.497 ± 0.018
0.108CysTrp: 0.108 ± 0.008
0.389CysTyr: 0.389 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
4.241AspAla: 4.241 ± 0.055
0.384AspCys: 0.384 ± 0.014
2.273AspAsp: 2.273 ± 0.043
2.81AspGlu: 2.81 ± 0.048
2.555AspPhe: 2.555 ± 0.043
3.644AspGly: 3.644 ± 0.051
0.898AspHis: 0.898 ± 0.021
3.614AspIle: 3.614 ± 0.046
3.413AspLys: 3.413 ± 0.049
4.474AspLeu: 4.474 ± 0.054
1.136AspMet: 1.136 ± 0.023
2.751AspAsn: 2.751 ± 0.04
2.109AspPro: 2.109 ± 0.037
1.567AspGln: 1.567 ± 0.031
2.037AspArg: 2.037 ± 0.034
3.171AspSer: 3.171 ± 0.044
2.709AspThr: 2.709 ± 0.045
3.229AspVal: 3.229 ± 0.052
0.751AspTrp: 0.751 ± 0.019
2.426AspTyr: 2.426 ± 0.04
0.0AspXaa: 0.0 ± 0.0
Glu
4.721GluAla: 4.721 ± 0.059
0.345GluCys: 0.345 ± 0.013
2.461GluAsp: 2.461 ± 0.045
3.58GluGlu: 3.58 ± 0.066
2.031GluPhe: 2.031 ± 0.036
3.484GluGly: 3.484 ± 0.05
1.051GluHis: 1.051 ± 0.028
3.537GluIle: 3.537 ± 0.056
4.374GluLys: 4.374 ± 0.064
5.346GluLeu: 5.346 ± 0.062
1.449GluMet: 1.449 ± 0.033
2.822GluAsn: 2.822 ± 0.04
1.57GluPro: 1.57 ± 0.032
2.68GluGln: 2.68 ± 0.052
2.621GluArg: 2.621 ± 0.046
2.546GluSer: 2.546 ± 0.041
2.847GluThr: 2.847 ± 0.04
3.599GluVal: 3.599 ± 0.046
0.755GluTrp: 0.755 ± 0.023
1.971GluTyr: 1.971 ± 0.041
0.0GluXaa: 0.0 ± 0.0
Phe
3.219PheAla: 3.219 ± 0.046
0.473PheCys: 0.473 ± 0.018
2.572PheAsp: 2.572 ± 0.041
2.406PheGlu: 2.406 ± 0.044
2.298PhePhe: 2.298 ± 0.048
3.051PheGly: 3.051 ± 0.045
0.86PheHis: 0.86 ± 0.024
3.023PheIle: 3.023 ± 0.048
2.579PheLys: 2.579 ± 0.043
4.123PheLeu: 4.123 ± 0.061
1.075PheMet: 1.075 ± 0.027
2.813PheAsn: 2.813 ± 0.045
1.76PhePro: 1.76 ± 0.031
1.441PheGln: 1.441 ± 0.026
2.247PheArg: 2.247 ± 0.038
3.727PheSer: 3.727 ± 0.051
3.114PheThr: 3.114 ± 0.044
2.714PheVal: 2.714 ± 0.042
0.575PheTrp: 0.575 ± 0.02
2.02PheTyr: 2.02 ± 0.039
0.0PheXaa: 0.0 ± 0.0
Gly
5.389GlyAla: 5.389 ± 0.076
0.718GlyCys: 0.718 ± 0.027
3.378GlyAsp: 3.378 ± 0.048
3.337GlyGlu: 3.337 ± 0.048
3.504GlyPhe: 3.504 ± 0.053
5.252GlyGly: 5.252 ± 0.09
1.247GlyHis: 1.247 ± 0.027
5.281GlyIle: 5.281 ± 0.071
5.101GlyLys: 5.101 ± 0.065
6.151GlyLeu: 6.151 ± 0.064
1.779GlyMet: 1.779 ± 0.032
4.101GlyAsn: 4.101 ± 0.06
1.63GlyPro: 1.63 ± 0.04
2.334GlyGln: 2.334 ± 0.04
3.007GlyArg: 3.007 ± 0.046
4.847GlySer: 4.847 ± 0.061
4.586GlyThr: 4.586 ± 0.076
4.6GlyVal: 4.6 ± 0.066
1.085GlyTrp: 1.085 ± 0.028
3.315GlyTyr: 3.315 ± 0.038
0.0GlyXaa: 0.0 ± 0.0
His
1.355HisAla: 1.355 ± 0.033
0.186HisCys: 0.186 ± 0.011
0.918HisAsp: 0.918 ± 0.023
0.998HisGlu: 0.998 ± 0.025
1.127HisPhe: 1.127 ± 0.024
1.069HisGly: 1.069 ± 0.029
0.557HisHis: 0.557 ± 0.02
1.347HisIle: 1.347 ± 0.029
0.965HisLys: 0.965 ± 0.026
1.961HisLeu: 1.961 ± 0.035
0.426HisMet: 0.426 ± 0.016
0.959HisAsn: 0.959 ± 0.022
1.035HisPro: 1.035 ± 0.025
0.721HisGln: 0.721 ± 0.021
0.85HisArg: 0.85 ± 0.024
1.146HisSer: 1.146 ± 0.026
1.077HisThr: 1.077 ± 0.026
1.036HisVal: 1.036 ± 0.024
0.272HisTrp: 0.272 ± 0.012
0.914HisTyr: 0.914 ± 0.024
0.0HisXaa: 0.0 ± 0.0
Ile
5.606IleAla: 5.606 ± 0.063
0.67IleCys: 0.67 ± 0.022
3.679IleAsp: 3.679 ± 0.046
3.602IleGlu: 3.602 ± 0.05
2.435IlePhe: 2.435 ± 0.045
4.415IleGly: 4.415 ± 0.058
1.262IleHis: 1.262 ± 0.03
4.153IleIle: 4.153 ± 0.054
3.879IleLys: 3.879 ± 0.046
5.257IleLeu: 5.257 ± 0.071
1.217IleMet: 1.217 ± 0.026
3.511IleAsn: 3.511 ± 0.051
3.005IlePro: 3.005 ± 0.043
2.278IleGln: 2.278 ± 0.044
3.223IleArg: 3.223 ± 0.049
4.624IleSer: 4.624 ± 0.057
4.595IleThr: 4.595 ± 0.069
4.091IleVal: 4.091 ± 0.055
0.708IleTrp: 0.708 ± 0.019
2.428IleTyr: 2.428 ± 0.04
0.0IleXaa: 0.0 ± 0.0
Lys
5.38LysAla: 5.38 ± 0.063
0.323LysCys: 0.323 ± 0.015
3.603LysAsp: 3.603 ± 0.053
4.279LysGlu: 4.279 ± 0.059
1.891LysPhe: 1.891 ± 0.043
4.481LysGly: 4.481 ± 0.055
1.128LysHis: 1.128 ± 0.029
3.764LysIle: 3.764 ± 0.057
4.583LysLys: 4.583 ± 0.057
5.461LysLeu: 5.461 ± 0.064
1.731LysMet: 1.731 ± 0.036
3.211LysAsn: 3.211 ± 0.046
2.599LysPro: 2.599 ± 0.05
2.887LysGln: 2.887 ± 0.049
2.802LysArg: 2.802 ± 0.048
3.153LysSer: 3.153 ± 0.039
3.645LysThr: 3.645 ± 0.042
3.937LysVal: 3.937 ± 0.049
0.832LysTrp: 0.832 ± 0.022
2.465LysTyr: 2.465 ± 0.036
0.0LysXaa: 0.0 ± 0.0
Leu
7.283LeuAla: 7.283 ± 0.07
0.877LeuCys: 0.877 ± 0.025
4.3LeuAsp: 4.3 ± 0.052
4.846LeuGlu: 4.846 ± 0.057
4.649LeuPhe: 4.649 ± 0.063
5.495LeuGly: 5.495 ± 0.063
1.908LeuHis: 1.908 ± 0.031
5.228LeuIle: 5.228 ± 0.077
6.196LeuLys: 6.196 ± 0.073
10.226LeuLeu: 10.226 ± 0.125
2.063LeuMet: 2.063 ± 0.037
5.005LeuAsn: 5.005 ± 0.061
4.682LeuPro: 4.682 ± 0.051
4.545LeuGln: 4.545 ± 0.057
4.27LeuArg: 4.27 ± 0.056
6.876LeuSer: 6.876 ± 0.067
5.277LeuThr: 5.277 ± 0.056
5.747LeuVal: 5.747 ± 0.062
1.044LeuTrp: 1.044 ± 0.03
3.573LeuTyr: 3.573 ± 0.051
0.0LeuXaa: 0.0 ± 0.0
Met
1.972MetAla: 1.972 ± 0.036
0.138MetCys: 0.138 ± 0.009
1.099MetAsp: 1.099 ± 0.024
1.319MetGlu: 1.319 ± 0.029
0.73MetPhe: 0.73 ± 0.023
1.493MetGly: 1.493 ± 0.031
0.463MetHis: 0.463 ± 0.017
1.346MetIle: 1.346 ± 0.032
1.906MetLys: 1.906 ± 0.035
2.183MetLeu: 2.183 ± 0.041
0.598MetMet: 0.598 ± 0.019
1.271MetAsn: 1.271 ± 0.028
1.162MetPro: 1.162 ± 0.026
1.164MetGln: 1.164 ± 0.025
1.139MetArg: 1.139 ± 0.025
1.367MetSer: 1.367 ± 0.03
1.121MetThr: 1.121 ± 0.025
1.415MetVal: 1.415 ± 0.03
0.184MetTrp: 0.184 ± 0.01
0.749MetTyr: 0.749 ± 0.017
0.0MetXaa: 0.0 ± 0.0
Asn
4.352AsnAla: 4.352 ± 0.056
0.439AsnCys: 0.439 ± 0.019
2.59AsnAsp: 2.59 ± 0.038
2.783AsnGlu: 2.783 ± 0.041
2.27AsnPhe: 2.27 ± 0.04
4.356AsnGly: 4.356 ± 0.06
0.882AsnHis: 0.882 ± 0.02
3.898AsnIle: 3.898 ± 0.054
3.323AsnLys: 3.323 ± 0.042
4.335AsnLeu: 4.335 ± 0.055
1.186AsnMet: 1.186 ± 0.028
3.368AsnAsn: 3.368 ± 0.067
2.537AsnPro: 2.537 ± 0.043
1.746AsnGln: 1.746 ± 0.035
2.518AsnArg: 2.518 ± 0.039
3.271AsnSer: 3.271 ± 0.053
3.544AsnThr: 3.544 ± 0.077
3.173AsnVal: 3.173 ± 0.051
0.782AsnTrp: 0.782 ± 0.022
2.568AsnTyr: 2.568 ± 0.046
0.0AsnXaa: 0.0 ± 0.0
Pro
4.384ProAla: 4.384 ± 0.058
0.275ProCys: 0.275 ± 0.013
2.538ProAsp: 2.538 ± 0.039
2.75ProGlu: 2.75 ± 0.037
1.933ProPhe: 1.933 ± 0.032
3.438ProGly: 3.438 ± 0.048
0.745ProHis: 0.745 ± 0.021
1.946ProIle: 1.946 ± 0.032
1.731ProLys: 1.731 ± 0.033
3.646ProLeu: 3.646 ± 0.046
0.82ProMet: 0.82 ± 0.023
1.696ProAsn: 1.696 ± 0.035
1.3ProPro: 1.3 ± 0.03
1.5ProGln: 1.5 ± 0.028
1.382ProArg: 1.382 ± 0.026
2.483ProSer: 2.483 ± 0.044
1.879ProThr: 1.879 ± 0.034
3.928ProVal: 3.928 ± 0.048
0.458ProTrp: 0.458 ± 0.017
1.646ProTyr: 1.646 ± 0.03
0.0ProXaa: 0.0 ± 0.0
Gln
3.071GlnAla: 3.071 ± 0.048
0.25GlnCys: 0.25 ± 0.01
1.635GlnAsp: 1.635 ± 0.031
2.24GlnGlu: 2.24 ± 0.037
1.72GlnPhe: 1.72 ± 0.032
2.19GlnGly: 2.19 ± 0.042
0.949GlnHis: 0.949 ± 0.023
1.986GlnIle: 1.986 ± 0.036
2.401GlnLys: 2.401 ± 0.039
4.747GlnLeu: 4.747 ± 0.07
0.976GlnMet: 0.976 ± 0.026
1.805GlnAsn: 1.805 ± 0.033
1.874GlnPro: 1.874 ± 0.041
2.927GlnGln: 2.927 ± 0.068
1.883GlnArg: 1.883 ± 0.035
2.312GlnSer: 2.312 ± 0.039
2.109GlnThr: 2.109 ± 0.036
2.781GlnVal: 2.781 ± 0.037
0.618GlnTrp: 0.618 ± 0.02
1.744GlnTyr: 1.744 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
2.741ArgAla: 2.741 ± 0.044
0.316ArgCys: 0.316 ± 0.015
2.074ArgAsp: 2.074 ± 0.036
2.473ArgGlu: 2.473 ± 0.04
2.481ArgPhe: 2.481 ± 0.04
2.381ArgGly: 2.381 ± 0.04
0.854ArgHis: 0.854 ± 0.023
3.374ArgIle: 3.374 ± 0.047
3.147ArgLys: 3.147 ± 0.049
4.522ArgLeu: 4.522 ± 0.053
1.255ArgMet: 1.255 ± 0.027
2.648ArgAsn: 2.648 ± 0.041
1.635ArgPro: 1.635 ± 0.031
2.003ArgGln: 2.003 ± 0.042
2.091ArgArg: 2.091 ± 0.04
2.704ArgSer: 2.704 ± 0.038
2.305ArgThr: 2.305 ± 0.037
2.672ArgVal: 2.672 ± 0.045
0.768ArgTrp: 0.768 ± 0.022
2.175ArgTyr: 2.175 ± 0.035
0.0ArgXaa: 0.0 ± 0.0
Ser
5.1SerAla: 5.1 ± 0.061
0.654SerCys: 0.654 ± 0.023
3.197SerAsp: 3.197 ± 0.044
2.878SerGlu: 2.878 ± 0.042
3.843SerPhe: 3.843 ± 0.058
5.275SerGly: 5.275 ± 0.08
1.163SerHis: 1.163 ± 0.032
4.255SerIle: 4.255 ± 0.053
3.374SerLys: 3.374 ± 0.053
6.401SerLeu: 6.401 ± 0.06
1.362SerMet: 1.362 ± 0.028
3.267SerAsn: 3.267 ± 0.054
2.415SerPro: 2.415 ± 0.038
2.136SerGln: 2.136 ± 0.04
2.904SerArg: 2.904 ± 0.042
4.334SerSer: 4.334 ± 0.07
3.454SerThr: 3.454 ± 0.06
4.42SerVal: 4.42 ± 0.055
0.926SerTrp: 0.926 ± 0.023
3.117SerTyr: 3.117 ± 0.056
0.0SerXaa: 0.0 ± 0.0
Thr
5.555ThrAla: 5.555 ± 0.071
0.458ThrCys: 0.458 ± 0.02
3.077ThrAsp: 3.077 ± 0.043
2.795ThrGlu: 2.795 ± 0.038
2.368ThrPhe: 2.368 ± 0.045
5.522ThrGly: 5.522 ± 0.085
0.998ThrHis: 0.998 ± 0.025
4.089ThrIle: 4.089 ± 0.058
2.678ThrLys: 2.678 ± 0.042
5.491ThrLeu: 5.491 ± 0.07
1.027ThrMet: 1.027 ± 0.024
2.899ThrAsn: 2.899 ± 0.055
3.013ThrPro: 3.013 ± 0.049
1.987ThrGln: 1.987 ± 0.032
2.43ThrArg: 2.43 ± 0.033
3.766ThrSer: 3.766 ± 0.072
3.938ThrThr: 3.938 ± 0.079
4.403ThrVal: 4.403 ± 0.081
0.719ThrTrp: 0.719 ± 0.024
2.485ThrTyr: 2.485 ± 0.054
0.0ThrXaa: 0.0 ± 0.0
Val
5.467ValAla: 5.467 ± 0.064
0.657ValCys: 0.657 ± 0.021
3.003ValAsp: 3.003 ± 0.051
3.157ValGlu: 3.157 ± 0.042
3.212ValPhe: 3.212 ± 0.041
3.487ValGly: 3.487 ± 0.053
1.191ValHis: 1.191 ± 0.027
4.578ValIle: 4.578 ± 0.056
4.425ValLys: 4.425 ± 0.052
6.211ValLeu: 6.211 ± 0.074
1.538ValMet: 1.538 ± 0.031
3.838ValAsn: 3.838 ± 0.059
2.711ValPro: 2.711 ± 0.04
2.371ValGln: 2.371 ± 0.04
2.729ValArg: 2.729 ± 0.044
4.609ValSer: 4.609 ± 0.059
4.482ValThr: 4.482 ± 0.065
4.536ValVal: 4.536 ± 0.068
0.7ValTrp: 0.7 ± 0.02
2.609ValTyr: 2.609 ± 0.044
0.0ValXaa: 0.0 ± 0.0
Trp
0.863TrpAla: 0.863 ± 0.023
0.152TrpCys: 0.152 ± 0.01
0.672TrpAsp: 0.672 ± 0.019
0.721TrpGlu: 0.721 ± 0.021
0.595TrpPhe: 0.595 ± 0.019
0.907TrpGly: 0.907 ± 0.024
0.301TrpHis: 0.301 ± 0.015
0.728TrpIle: 0.728 ± 0.026
0.882TrpLys: 0.882 ± 0.023
1.322TrpLeu: 1.322 ± 0.031
0.397TrpMet: 0.397 ± 0.014
0.778TrpAsn: 0.778 ± 0.024
0.397TrpPro: 0.397 ± 0.016
0.709TrpGln: 0.709 ± 0.021
0.608TrpArg: 0.608 ± 0.02
0.776TrpSer: 0.776 ± 0.025
0.669TrpThr: 0.669 ± 0.022
0.757TrpVal: 0.757 ± 0.023
0.23TrpTrp: 0.23 ± 0.012
0.6TrpTyr: 0.6 ± 0.022
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.195TyrAla: 3.195 ± 0.044
0.396TyrCys: 0.396 ± 0.017
2.346TyrAsp: 2.346 ± 0.052
2.072TyrGlu: 2.072 ± 0.041
2.118TyrPhe: 2.118 ± 0.04
2.925TyrGly: 2.925 ± 0.046
0.902TyrHis: 0.902 ± 0.022
2.377TyrIle: 2.377 ± 0.037
2.597TyrLys: 2.597 ± 0.046
3.83TyrLeu: 3.83 ± 0.047
0.821TyrMet: 0.821 ± 0.021
2.741TyrAsn: 2.741 ± 0.053
1.76TyrPro: 1.76 ± 0.035
1.779TyrGln: 1.779 ± 0.027
2.159TyrArg: 2.159 ± 0.041
2.783TyrSer: 2.783 ± 0.047
2.802TyrThr: 2.802 ± 0.047
2.24TyrVal: 2.24 ± 0.035
0.549TyrTrp: 0.549 ± 0.02
2.154TyrTyr: 2.154 ± 0.045
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4638 proteins (1792117 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski