Amino acid dipepetide frequency for Beihai picorna-like virus 58

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.582AlaAla: 4.582 ± 0.363
1.145AlaCys: 1.145 ± 0.613
3.818AlaAsp: 3.818 ± 1.476
3.818AlaGlu: 3.818 ± 1.34
1.527AlaPhe: 1.527 ± 0.114
4.964AlaGly: 4.964 ± 0.863
3.055AlaHis: 3.055 ± 0.932
4.2AlaIle: 4.2 ± 0.841
3.818AlaLys: 3.818 ± 1.34
6.109AlaLeu: 6.109 ± 1.863
4.2AlaMet: 4.2 ± 1.272
2.291AlaAsn: 2.291 ± 0.886
3.436AlaPro: 3.436 ± 0.432
3.055AlaGln: 3.055 ± 0.227
4.2AlaArg: 4.2 ± 0.841
3.436AlaSer: 3.436 ± 0.976
3.055AlaThr: 3.055 ± 0.477
4.964AlaVal: 4.964 ± 1.25
2.291AlaTrp: 2.291 ± 0.181
2.673AlaTyr: 2.673 ± 0.023
0.0AlaXaa: 0.0 ± 0.0
Cys
1.527CysAla: 1.527 ± 0.818
0.764CysCys: 0.764 ± 0.409
1.145CysAsp: 1.145 ± 0.091
2.291CysGlu: 2.291 ± 0.181
0.764CysPhe: 0.764 ± 0.295
2.291CysGly: 2.291 ± 0.523
0.0CysHis: 0.0 ± 0.0
0.764CysIle: 0.764 ± 0.295
0.0CysLys: 0.0 ± 0.0
1.909CysLeu: 1.909 ± 1.022
0.0CysMet: 0.0 ± 0.0
1.145CysAsn: 1.145 ± 0.091
0.764CysPro: 0.764 ± 0.409
0.764CysGln: 0.764 ± 0.295
0.382CysArg: 0.382 ± 0.5
3.436CysSer: 3.436 ± 0.272
2.291CysThr: 2.291 ± 0.181
1.909CysVal: 1.909 ± 0.318
0.382CysTrp: 0.382 ± 0.204
1.527CysTyr: 1.527 ± 0.59
0.0CysXaa: 0.0 ± 0.0
Asp
3.055AspAla: 3.055 ± 1.181
1.145AspCys: 1.145 ± 0.091
4.2AspAsp: 4.2 ± 0.841
2.291AspGlu: 2.291 ± 0.886
2.291AspPhe: 2.291 ± 0.523
3.055AspGly: 3.055 ± 0.932
1.145AspHis: 1.145 ± 0.091
3.055AspIle: 3.055 ± 0.227
2.673AspLys: 2.673 ± 0.727
6.109AspLeu: 6.109 ± 0.455
1.145AspMet: 1.145 ± 0.613
1.909AspAsn: 1.909 ± 0.386
2.291AspPro: 2.291 ± 0.886
1.145AspGln: 1.145 ± 0.091
2.673AspArg: 2.673 ± 1.431
2.673AspSer: 2.673 ± 0.727
4.582AspThr: 4.582 ± 0.363
4.2AspVal: 4.2 ± 1.545
1.527AspTrp: 1.527 ± 0.59
1.909AspTyr: 1.909 ± 0.386
0.0AspXaa: 0.0 ± 0.0
Glu
2.673GluAla: 2.673 ± 0.023
1.909GluCys: 1.909 ± 0.318
3.055GluAsp: 3.055 ± 0.227
1.145GluGlu: 1.145 ± 0.613
3.055GluPhe: 3.055 ± 0.932
4.964GluGly: 4.964 ± 0.863
1.145GluHis: 1.145 ± 0.613
1.909GluIle: 1.909 ± 0.386
3.055GluLys: 3.055 ± 0.227
5.346GluLeu: 5.346 ± 0.75
1.909GluMet: 1.909 ± 0.505
1.145GluAsn: 1.145 ± 0.613
1.527GluPro: 1.527 ± 0.818
0.382GluGln: 0.382 ± 0.204
2.673GluArg: 2.673 ± 0.023
3.055GluSer: 3.055 ± 1.181
1.909GluThr: 1.909 ± 0.318
3.436GluVal: 3.436 ± 0.432
0.764GluTrp: 0.764 ± 0.409
2.673GluTyr: 2.673 ± 0.681
0.0GluXaa: 0.0 ± 0.0
Phe
4.2PheAla: 4.2 ± 0.137
1.145PheCys: 1.145 ± 0.091
3.055PheAsp: 3.055 ± 0.932
1.527PheGlu: 1.527 ± 0.114
1.909PhePhe: 1.909 ± 1.022
5.346PheGly: 5.346 ± 0.046
1.527PheHis: 1.527 ± 0.59
3.818PheIle: 3.818 ± 0.636
1.527PheLys: 1.527 ± 0.114
4.2PheLeu: 4.2 ± 2.249
1.145PheMet: 1.145 ± 0.613
2.291PheAsn: 2.291 ± 0.181
1.527PhePro: 1.527 ± 0.114
1.145PheGln: 1.145 ± 0.091
1.909PheArg: 1.909 ± 0.318
4.2PheSer: 4.2 ± 0.841
3.818PheThr: 3.818 ± 2.045
3.818PheVal: 3.818 ± 0.772
0.382PheTrp: 0.382 ± 0.204
1.909PheTyr: 1.909 ± 1.022
0.0PheXaa: 0.0 ± 0.0
Gly
3.818GlyAla: 3.818 ± 0.772
0.764GlyCys: 0.764 ± 0.295
4.964GlyAsp: 4.964 ± 1.25
2.673GlyGlu: 2.673 ± 1.385
2.673GlyPhe: 2.673 ± 0.023
3.818GlyGly: 3.818 ± 0.068
3.055GlyHis: 3.055 ± 0.227
2.673GlyIle: 2.673 ± 0.727
3.436GlyLys: 3.436 ± 0.272
9.546GlyLeu: 9.546 ± 0.887
1.527GlyMet: 1.527 ± 0.114
3.818GlyAsn: 3.818 ± 2.18
3.818GlyPro: 3.818 ± 0.772
0.764GlyGln: 0.764 ± 0.295
3.818GlyArg: 3.818 ± 0.636
6.491GlySer: 6.491 ± 2.157
4.2GlyThr: 4.2 ± 0.567
6.109GlyVal: 6.109 ± 1.159
0.382GlyTrp: 0.382 ± 0.204
2.673GlyTyr: 2.673 ± 0.023
0.0GlyXaa: 0.0 ± 0.0
His
1.145HisAla: 1.145 ± 0.613
0.764HisCys: 0.764 ± 0.409
1.909HisAsp: 1.909 ± 0.318
1.909HisGlu: 1.909 ± 0.318
2.291HisPhe: 2.291 ± 0.523
0.382HisGly: 0.382 ± 0.204
0.382HisHis: 0.382 ± 0.204
0.382HisIle: 0.382 ± 0.5
0.382HisLys: 0.382 ± 0.204
1.909HisLeu: 1.909 ± 1.09
1.527HisMet: 1.527 ± 0.818
0.764HisAsn: 0.764 ± 0.409
1.145HisPro: 1.145 ± 0.091
0.382HisGln: 0.382 ± 0.204
1.909HisArg: 1.909 ± 1.09
1.145HisSer: 1.145 ± 0.091
0.764HisThr: 0.764 ± 0.295
1.145HisVal: 1.145 ± 0.613
0.382HisTrp: 0.382 ± 0.204
1.145HisTyr: 1.145 ± 0.091
0.0HisXaa: 0.0 ± 0.0
Ile
5.346IleAla: 5.346 ± 0.75
1.145IleCys: 1.145 ± 0.613
2.291IleAsp: 2.291 ± 0.886
2.291IleGlu: 2.291 ± 0.886
2.291IlePhe: 2.291 ± 1.227
2.673IleGly: 2.673 ± 0.727
1.145IleHis: 1.145 ± 0.613
0.382IleIle: 0.382 ± 0.204
3.436IleLys: 3.436 ± 0.272
6.491IleLeu: 6.491 ± 1.363
1.145IleMet: 1.145 ± 0.613
1.909IleAsn: 1.909 ± 0.386
1.909IlePro: 1.909 ± 0.386
1.909IleGln: 1.909 ± 0.386
1.527IleArg: 1.527 ± 0.818
2.291IleSer: 2.291 ± 0.523
1.909IleThr: 1.909 ± 1.794
3.055IleVal: 3.055 ± 0.932
0.764IleTrp: 0.764 ± 0.295
3.818IleTyr: 3.818 ± 0.772
0.0IleXaa: 0.0 ± 0.0
Lys
4.2LysAla: 4.2 ± 2.249
0.382LysCys: 0.382 ± 0.5
3.055LysAsp: 3.055 ± 1.636
3.055LysGlu: 3.055 ± 1.636
2.291LysPhe: 2.291 ± 0.181
2.291LysGly: 2.291 ± 0.523
0.764LysHis: 0.764 ± 0.409
3.818LysIle: 3.818 ± 0.068
1.145LysLys: 1.145 ± 0.091
6.873LysLeu: 6.873 ± 0.864
0.382LysMet: 0.382 ± 0.204
2.291LysAsn: 2.291 ± 0.523
3.055LysPro: 3.055 ± 0.477
0.0LysGln: 0.0 ± 0.0
1.909LysArg: 1.909 ± 0.318
4.582LysSer: 4.582 ± 0.363
2.673LysThr: 2.673 ± 0.727
5.346LysVal: 5.346 ± 0.658
0.0LysTrp: 0.0 ± 0.0
0.382LysTyr: 0.382 ± 0.5
0.0LysXaa: 0.0 ± 0.0
Leu
8.782LeuAla: 8.782 ± 0.478
1.909LeuCys: 1.909 ± 0.386
4.582LeuAsp: 4.582 ± 0.363
4.964LeuGlu: 4.964 ± 0.863
6.873LeuPhe: 6.873 ± 2.976
6.491LeuGly: 6.491 ± 0.659
1.909LeuHis: 1.909 ± 1.022
4.964LeuIle: 4.964 ± 0.546
5.727LeuLys: 5.727 ± 0.454
7.255LeuLeu: 7.255 ± 2.477
1.145LeuMet: 1.145 ± 0.795
5.346LeuAsn: 5.346 ± 0.046
3.055LeuPro: 3.055 ± 0.227
3.055LeuGln: 3.055 ± 1.181
4.2LeuArg: 4.2 ± 0.567
6.491LeuSer: 6.491 ± 0.749
6.491LeuThr: 6.491 ± 2.157
5.346LeuVal: 5.346 ± 2.862
2.673LeuTrp: 2.673 ± 1.431
1.909LeuTyr: 1.909 ± 1.022
0.0LeuXaa: 0.0 ± 0.0
Met
2.673MetAla: 2.673 ± 0.023
0.382MetCys: 0.382 ± 0.204
1.909MetAsp: 1.909 ± 0.386
1.909MetGlu: 1.909 ± 0.386
1.527MetPhe: 1.527 ± 0.114
3.055MetGly: 3.055 ± 0.227
0.764MetHis: 0.764 ± 0.295
0.764MetIle: 0.764 ± 0.295
1.145MetLys: 1.145 ± 0.613
0.382MetLeu: 0.382 ± 0.5
0.382MetMet: 0.382 ± 0.204
1.145MetAsn: 1.145 ± 0.091
1.909MetPro: 1.909 ± 0.318
0.382MetGln: 0.382 ± 0.204
1.527MetArg: 1.527 ± 1.295
2.291MetSer: 2.291 ± 0.523
1.527MetThr: 1.527 ± 1.295
2.673MetVal: 2.673 ± 0.681
0.0MetTrp: 0.0 ± 0.0
1.145MetTyr: 1.145 ± 0.091
0.0MetXaa: 0.0 ± 0.0
Asn
2.673AsnAla: 2.673 ± 0.023
0.764AsnCys: 0.764 ± 0.409
2.673AsnAsp: 2.673 ± 0.023
1.527AsnGlu: 1.527 ± 0.114
2.291AsnPhe: 2.291 ± 1.59
3.055AsnGly: 3.055 ± 1.181
0.764AsnHis: 0.764 ± 0.999
1.909AsnIle: 1.909 ± 0.318
2.291AsnLys: 2.291 ± 0.523
2.291AsnLeu: 2.291 ± 0.886
0.764AsnMet: 0.764 ± 0.999
1.527AsnAsn: 1.527 ± 1.295
3.436AsnPro: 3.436 ± 0.272
1.527AsnGln: 1.527 ± 0.59
2.291AsnArg: 2.291 ± 0.181
4.2AsnSer: 4.2 ± 0.567
3.055AsnThr: 3.055 ± 0.932
1.527AsnVal: 1.527 ± 0.114
1.527AsnTrp: 1.527 ± 0.114
1.527AsnTyr: 1.527 ± 0.114
0.0AsnXaa: 0.0 ± 0.0
Pro
3.055ProAla: 3.055 ± 0.227
1.145ProCys: 1.145 ± 0.613
2.673ProAsp: 2.673 ± 0.681
3.436ProGlu: 3.436 ± 0.432
2.673ProPhe: 2.673 ± 0.727
1.527ProGly: 1.527 ± 0.59
0.764ProHis: 0.764 ± 0.295
2.673ProIle: 2.673 ± 1.431
0.764ProLys: 0.764 ± 0.409
3.436ProLeu: 3.436 ± 0.976
1.527ProMet: 1.527 ± 1.295
1.909ProAsn: 1.909 ± 0.386
1.527ProPro: 1.527 ± 0.114
1.527ProGln: 1.527 ± 0.59
1.527ProArg: 1.527 ± 0.114
4.2ProSer: 4.2 ± 0.137
1.909ProThr: 1.909 ± 1.794
3.818ProVal: 3.818 ± 0.772
0.764ProTrp: 0.764 ± 0.999
2.673ProTyr: 2.673 ± 0.681
0.0ProXaa: 0.0 ± 0.0
Gln
2.291GlnAla: 2.291 ± 0.523
0.382GlnCys: 0.382 ± 0.204
0.382GlnAsp: 0.382 ± 0.204
0.382GlnGlu: 0.382 ± 0.204
0.382GlnPhe: 0.382 ± 0.204
1.145GlnGly: 1.145 ± 0.091
0.0GlnHis: 0.0 ± 0.0
1.527GlnIle: 1.527 ± 0.114
1.527GlnLys: 1.527 ± 0.59
3.055GlnLeu: 3.055 ± 0.227
0.382GlnMet: 0.382 ± 0.204
1.527GlnAsn: 1.527 ± 0.59
0.382GlnPro: 0.382 ± 0.5
0.0GlnGln: 0.0 ± 0.0
1.909GlnArg: 1.909 ± 0.386
3.818GlnSer: 3.818 ± 0.772
1.527GlnThr: 1.527 ± 1.295
1.909GlnVal: 1.909 ± 1.794
0.764GlnTrp: 0.764 ± 0.295
1.909GlnTyr: 1.909 ± 0.386
0.0GlnXaa: 0.0 ± 0.0
Arg
3.055ArgAla: 3.055 ± 0.932
3.055ArgCys: 3.055 ± 0.227
0.764ArgAsp: 0.764 ± 0.409
2.673ArgGlu: 2.673 ± 1.431
2.291ArgPhe: 2.291 ± 0.523
1.909ArgGly: 1.909 ± 1.09
0.764ArgHis: 0.764 ± 0.409
4.582ArgIle: 4.582 ± 1.067
1.909ArgLys: 1.909 ± 1.022
5.727ArgLeu: 5.727 ± 0.25
1.527ArgMet: 1.527 ± 0.818
1.909ArgAsn: 1.909 ± 0.318
1.145ArgPro: 1.145 ± 0.795
1.145ArgGln: 1.145 ± 0.795
3.818ArgArg: 3.818 ± 2.045
4.582ArgSer: 4.582 ± 1.067
2.291ArgThr: 2.291 ± 0.886
4.582ArgVal: 4.582 ± 1.045
0.764ArgTrp: 0.764 ± 0.409
2.291ArgTyr: 2.291 ± 0.523
0.0ArgXaa: 0.0 ± 0.0
Ser
4.964SerAla: 4.964 ± 0.863
1.909SerCys: 1.909 ± 1.09
4.964SerAsp: 4.964 ± 0.546
4.2SerGlu: 4.2 ± 0.137
3.818SerPhe: 3.818 ± 1.34
8.782SerGly: 8.782 ± 2.339
1.145SerHis: 1.145 ± 0.795
2.673SerIle: 2.673 ± 0.023
3.818SerLys: 3.818 ± 0.636
8.4SerLeu: 8.4 ± 1.839
1.145SerMet: 1.145 ± 0.091
3.055SerAsn: 3.055 ± 1.885
3.055SerPro: 3.055 ± 1.181
1.909SerGln: 1.909 ± 0.386
1.909SerArg: 1.909 ± 0.318
6.109SerSer: 6.109 ± 1.657
9.546SerThr: 9.546 ± 1.93
4.582SerVal: 4.582 ± 1.067
0.382SerTrp: 0.382 ± 0.204
3.818SerTyr: 3.818 ± 0.772
0.0SerXaa: 0.0 ± 0.0
Thr
3.055ThrAla: 3.055 ± 1.181
1.527ThrCys: 1.527 ± 1.295
2.291ThrAsp: 2.291 ± 0.181
1.145ThrGlu: 1.145 ± 0.613
4.2ThrPhe: 4.2 ± 0.567
5.727ThrGly: 5.727 ± 0.25
1.145ThrHis: 1.145 ± 0.613
3.818ThrIle: 3.818 ± 0.772
3.055ThrLys: 3.055 ± 0.477
5.346ThrLeu: 5.346 ± 0.046
2.291ThrMet: 2.291 ± 0.181
3.055ThrAsn: 3.055 ± 0.477
3.436ThrPro: 3.436 ± 1.68
2.291ThrGln: 2.291 ± 0.181
4.2ThrArg: 4.2 ± 0.137
4.582ThrSer: 4.582 ± 0.341
5.346ThrThr: 5.346 ± 2.158
3.055ThrVal: 3.055 ± 1.885
0.382ThrTrp: 0.382 ± 0.204
5.346ThrTyr: 5.346 ± 1.362
0.0ThrXaa: 0.0 ± 0.0
Val
5.346ValAla: 5.346 ± 0.046
1.909ValCys: 1.909 ± 0.318
0.764ValAsp: 0.764 ± 0.409
2.291ValGlu: 2.291 ± 0.523
4.582ValPhe: 4.582 ± 1.749
6.109ValGly: 6.109 ± 0.455
0.0ValHis: 0.0 ± 0.0
3.436ValIle: 3.436 ± 1.136
4.2ValLys: 4.2 ± 2.249
4.964ValLeu: 4.964 ± 0.158
3.436ValMet: 3.436 ± 0.536
3.436ValAsn: 3.436 ± 0.432
3.818ValPro: 3.818 ± 0.636
2.673ValGln: 2.673 ± 0.681
2.673ValArg: 2.673 ± 0.727
8.018ValSer: 8.018 ± 4.156
3.818ValThr: 3.818 ± 0.068
7.637ValVal: 7.637 ± 0.84
1.527ValTrp: 1.527 ± 0.114
4.2ValTyr: 4.2 ± 0.137
0.0ValXaa: 0.0 ± 0.0
Trp
1.145TrpAla: 1.145 ± 0.613
0.764TrpCys: 0.764 ± 0.295
1.145TrpAsp: 1.145 ± 0.613
0.764TrpGlu: 0.764 ± 0.409
1.145TrpPhe: 1.145 ± 0.795
0.764TrpGly: 0.764 ± 0.999
0.382TrpHis: 0.382 ± 0.204
0.0TrpIle: 0.0 ± 0.0
0.382TrpLys: 0.382 ± 0.5
2.291TrpLeu: 2.291 ± 0.886
0.0TrpMet: 0.0 ± 0.0
0.382TrpAsn: 0.382 ± 0.204
0.0TrpPro: 0.0 ± 0.0
0.382TrpGln: 0.382 ± 0.204
1.909TrpArg: 1.909 ± 0.386
1.145TrpSer: 1.145 ± 0.091
1.527TrpThr: 1.527 ± 0.114
1.909TrpVal: 1.909 ± 1.022
0.382TrpTrp: 0.382 ± 0.204
0.764TrpTyr: 0.764 ± 0.409
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.055TyrAla: 3.055 ± 0.227
1.145TyrCys: 1.145 ± 0.613
3.436TyrAsp: 3.436 ± 0.272
3.436TyrGlu: 3.436 ± 0.272
1.527TyrPhe: 1.527 ± 0.114
2.673TyrGly: 2.673 ± 0.023
1.909TyrHis: 1.909 ± 0.386
0.382TyrIle: 0.382 ± 0.5
4.2TyrLys: 4.2 ± 0.841
1.527TyrLeu: 1.527 ± 0.114
1.527TyrMet: 1.527 ± 1.295
0.764TyrAsn: 0.764 ± 0.409
2.291TyrPro: 2.291 ± 0.886
0.764TyrGln: 0.764 ± 0.295
3.818TyrArg: 3.818 ± 1.34
3.436TyrSer: 3.436 ± 1.68
3.055TyrThr: 3.055 ± 0.932
4.2TyrVal: 4.2 ± 0.567
1.145TyrTrp: 1.145 ± 1.499
1.527TyrTyr: 1.527 ± 0.818
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2620 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski