Amino acid dipepetide frequency for Rhynchosia golden mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.984AlaAla: 1.984 ± 0.69
0.661AlaCys: 0.661 ± 0.571
1.984AlaAsp: 1.984 ± 1.089
1.323AlaGlu: 1.323 ± 0.906
1.984AlaPhe: 1.984 ± 1.441
1.984AlaGly: 1.984 ± 1.233
1.323AlaHis: 1.323 ± 0.733
3.968AlaIle: 3.968 ± 1.919
5.291AlaLys: 5.291 ± 1.509
3.968AlaLeu: 3.968 ± 1.619
0.661AlaMet: 0.661 ± 0.526
3.307AlaAsn: 3.307 ± 1.001
2.646AlaPro: 2.646 ± 1.382
2.646AlaGln: 2.646 ± 1.445
3.968AlaArg: 3.968 ± 1.494
5.952AlaSer: 5.952 ± 2.181
4.63AlaThr: 4.63 ± 1.413
1.323AlaVal: 1.323 ± 1.467
1.323AlaTrp: 1.323 ± 0.606
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.661CysAla: 0.661 ± 0.785
0.661CysCys: 0.661 ± 0.785
0.661CysAsp: 0.661 ± 0.541
0.661CysGlu: 0.661 ± 0.571
0.0CysPhe: 0.0 ± 0.0
1.323CysGly: 1.323 ± 0.906
0.0CysHis: 0.0 ± 0.0
1.323CysIle: 1.323 ± 0.653
1.323CysLys: 1.323 ± 0.606
0.661CysLeu: 0.661 ± 0.698
0.661CysMet: 0.661 ± 0.573
2.646CysAsn: 2.646 ± 1.133
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.661CysArg: 0.661 ± 0.541
3.307CysSer: 3.307 ± 1.766
0.661CysThr: 0.661 ± 0.571
1.323CysVal: 1.323 ± 0.653
1.323CysTrp: 1.323 ± 1.397
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.984AspAla: 1.984 ± 0.607
0.0AspCys: 0.0 ± 0.0
2.646AspAsp: 2.646 ± 1.504
1.984AspGlu: 1.984 ± 0.77
1.984AspPhe: 1.984 ± 0.942
3.307AspGly: 3.307 ± 1.769
1.323AspHis: 1.323 ± 0.794
1.323AspIle: 1.323 ± 0.653
1.984AspLys: 1.984 ± 0.806
7.275AspLeu: 7.275 ± 1.638
0.661AspMet: 0.661 ± 0.698
2.646AspAsn: 2.646 ± 0.941
1.323AspPro: 1.323 ± 1.145
1.323AspGln: 1.323 ± 0.832
1.984AspArg: 1.984 ± 1.233
6.614AspSer: 6.614 ± 2.132
3.307AspThr: 3.307 ± 1.497
5.291AspVal: 5.291 ± 1.02
1.323AspTrp: 1.323 ± 1.082
1.323AspTyr: 1.323 ± 0.794
0.0AspXaa: 0.0 ± 0.0
Glu
2.646GluAla: 2.646 ± 1.484
0.661GluCys: 0.661 ± 0.573
0.0GluAsp: 0.0 ± 0.0
3.968GluGlu: 3.968 ± 2.642
1.984GluPhe: 1.984 ± 1.083
3.968GluGly: 3.968 ± 1.876
0.0GluHis: 0.0 ± 0.0
1.984GluIle: 1.984 ± 1.202
1.323GluLys: 1.323 ± 0.733
1.984GluLeu: 1.984 ± 1.439
0.0GluMet: 0.0 ± 0.0
4.63GluAsn: 4.63 ± 1.888
3.307GluPro: 3.307 ± 0.968
1.323GluGln: 1.323 ± 0.606
1.323GluArg: 1.323 ± 0.794
3.307GluSer: 3.307 ± 1.394
1.984GluThr: 1.984 ± 1.178
2.646GluVal: 2.646 ± 1.694
1.323GluTrp: 1.323 ± 0.906
1.984GluTyr: 1.984 ± 1.187
0.0GluXaa: 0.0 ± 0.0
Phe
0.661PheAla: 0.661 ± 0.573
0.661PheCys: 0.661 ± 0.571
3.307PheAsp: 3.307 ± 1.269
1.323PheGlu: 1.323 ± 0.606
3.968PhePhe: 3.968 ± 1.777
1.984PheGly: 1.984 ± 0.77
1.984PheHis: 1.984 ± 1.135
1.984PheIle: 1.984 ± 0.825
6.614PheLys: 6.614 ± 2.985
1.984PheLeu: 1.984 ± 1.622
0.661PheMet: 0.661 ± 0.541
3.307PheAsn: 3.307 ± 0.614
2.646PhePro: 2.646 ± 1.133
3.968PheGln: 3.968 ± 1.11
1.323PheArg: 1.323 ± 0.723
3.307PheSer: 3.307 ± 1.624
1.323PheThr: 1.323 ± 0.906
1.984PheVal: 1.984 ± 1.455
1.984PheTrp: 1.984 ± 1.447
2.646PheTyr: 2.646 ± 1.424
0.0PheXaa: 0.0 ± 0.0
Gly
2.646GlyAla: 2.646 ± 0.927
1.984GlyCys: 1.984 ± 1.048
2.646GlyAsp: 2.646 ± 1.133
1.984GlyGlu: 1.984 ± 1.04
0.661GlyPhe: 0.661 ± 0.785
4.63GlyGly: 4.63 ± 2.334
1.323GlyHis: 1.323 ± 0.906
1.323GlyIle: 1.323 ± 0.606
6.614GlyLys: 6.614 ± 1.754
3.307GlyLeu: 3.307 ± 1.105
0.661GlyMet: 0.661 ± 0.619
1.984GlyAsn: 1.984 ± 1.508
4.63GlyPro: 4.63 ± 0.882
4.63GlyGln: 4.63 ± 1.63
1.984GlyArg: 1.984 ± 1.187
5.291GlySer: 5.291 ± 1.361
3.307GlyThr: 3.307 ± 1.9
2.646GlyVal: 2.646 ± 1.833
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.661HisAla: 0.661 ± 0.571
1.323HisCys: 1.323 ± 0.839
2.646HisAsp: 2.646 ± 1.078
1.323HisGlu: 1.323 ± 0.917
2.646HisPhe: 2.646 ± 1.633
1.323HisGly: 1.323 ± 0.907
0.661HisHis: 0.661 ± 0.785
1.984HisIle: 1.984 ± 1.265
1.984HisLys: 1.984 ± 0.952
2.646HisLeu: 2.646 ± 1.467
0.661HisMet: 0.661 ± 0.698
3.307HisAsn: 3.307 ± 1.119
1.323HisPro: 1.323 ± 0.723
2.646HisGln: 2.646 ± 0.946
2.646HisArg: 2.646 ± 1.607
1.984HisSer: 1.984 ± 0.763
4.63HisThr: 4.63 ± 1.753
2.646HisVal: 2.646 ± 0.54
0.0HisTrp: 0.0 ± 0.0
1.323HisTyr: 1.323 ± 0.723
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.661IleCys: 0.661 ± 0.541
4.63IleAsp: 4.63 ± 1.528
3.968IleGlu: 3.968 ± 1.726
2.646IlePhe: 2.646 ± 1.727
0.661IleGly: 0.661 ± 0.573
2.646IleHis: 2.646 ± 1.133
2.646IleIle: 2.646 ± 1.445
4.63IleLys: 4.63 ± 1.356
2.646IleLeu: 2.646 ± 1.078
0.661IleMet: 0.661 ± 0.571
3.307IleAsn: 3.307 ± 1.024
1.984IlePro: 1.984 ± 1.187
2.646IleGln: 2.646 ± 1.594
5.291IleArg: 5.291 ± 1.463
4.63IleSer: 4.63 ± 1.257
5.291IleThr: 5.291 ± 0.938
1.984IleVal: 1.984 ± 0.806
0.661IleTrp: 0.661 ± 0.734
3.307IleTyr: 3.307 ± 1.297
0.0IleXaa: 0.0 ± 0.0
Lys
1.984LysAla: 1.984 ± 0.825
0.0LysCys: 0.0 ± 0.0
3.307LysAsp: 3.307 ± 1.46
3.307LysGlu: 3.307 ± 2.128
1.323LysPhe: 1.323 ± 0.653
2.646LysGly: 2.646 ± 0.54
1.323LysHis: 1.323 ± 0.723
5.291LysIle: 5.291 ± 1.205
0.661LysLys: 0.661 ± 0.541
4.63LysLeu: 4.63 ± 1.801
1.984LysMet: 1.984 ± 0.839
4.63LysAsn: 4.63 ± 1.392
3.968LysPro: 3.968 ± 1.111
0.661LysGln: 0.661 ± 0.573
5.952LysArg: 5.952 ± 2.449
5.952LysSer: 5.952 ± 1.023
1.323LysThr: 1.323 ± 0.906
7.275LysVal: 7.275 ± 3.848
0.0LysTrp: 0.0 ± 0.0
3.307LysTyr: 3.307 ± 1.502
0.0LysXaa: 0.0 ± 0.0
Leu
1.984LeuAla: 1.984 ± 0.763
1.984LeuCys: 1.984 ± 0.996
3.968LeuAsp: 3.968 ± 1.042
1.323LeuGlu: 1.323 ± 1.088
1.984LeuPhe: 1.984 ± 1.079
4.63LeuGly: 4.63 ± 1.268
3.307LeuHis: 3.307 ± 1.172
1.323LeuIle: 1.323 ± 0.832
5.291LeuLys: 5.291 ± 1.831
3.968LeuLeu: 3.968 ± 1.709
1.984LeuMet: 1.984 ± 1.049
5.291LeuAsn: 5.291 ± 2.542
1.984LeuPro: 1.984 ± 0.851
5.952LeuGln: 5.952 ± 1.959
3.968LeuArg: 3.968 ± 1.304
6.614LeuSer: 6.614 ± 1.725
1.984LeuThr: 1.984 ± 0.806
5.952LeuVal: 5.952 ± 1.534
0.0LeuTrp: 0.0 ± 0.0
1.984LeuTyr: 1.984 ± 0.952
0.0LeuXaa: 0.0 ± 0.0
Met
2.646MetAla: 2.646 ± 1.099
0.0MetCys: 0.0 ± 0.0
3.307MetAsp: 3.307 ± 1.282
0.0MetGlu: 0.0 ± 0.0
1.323MetPhe: 1.323 ± 1.143
1.323MetGly: 1.323 ± 0.832
0.661MetHis: 0.661 ± 0.571
0.0MetIle: 0.0 ± 0.0
0.661MetLys: 0.661 ± 0.573
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.323MetAsn: 1.323 ± 0.823
1.323MetPro: 1.323 ± 0.606
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
3.307MetSer: 3.307 ± 1.511
1.984MetThr: 1.984 ± 1.089
0.661MetVal: 0.661 ± 0.698
0.0MetTrp: 0.0 ± 0.0
1.984MetTyr: 1.984 ± 1.233
0.0MetXaa: 0.0 ± 0.0
Asn
6.614AsnAla: 6.614 ± 1.927
2.646AsnCys: 2.646 ± 0.767
3.968AsnAsp: 3.968 ± 1.302
4.63AsnGlu: 4.63 ± 0.915
1.323AsnPhe: 1.323 ± 0.917
1.984AsnGly: 1.984 ± 1.164
3.968AsnHis: 3.968 ± 2.609
3.307AsnIle: 3.307 ± 0.874
1.984AsnLys: 1.984 ± 1.268
3.968AsnLeu: 3.968 ± 1.963
1.323AsnMet: 1.323 ± 1.189
2.646AsnAsn: 2.646 ± 1.12
5.291AsnPro: 5.291 ± 1.535
1.984AsnGln: 1.984 ± 1.415
4.63AsnArg: 4.63 ± 0.915
1.984AsnSer: 1.984 ± 0.77
0.661AsnThr: 0.661 ± 0.764
3.307AsnVal: 3.307 ± 1.541
0.0AsnTrp: 0.0 ± 0.0
3.968AsnTyr: 3.968 ± 1.161
0.0AsnXaa: 0.0 ± 0.0
Pro
2.646ProAla: 2.646 ± 1.053
0.661ProCys: 0.661 ± 0.571
0.661ProAsp: 0.661 ± 0.571
1.323ProGlu: 1.323 ± 0.733
1.984ProPhe: 1.984 ± 1.141
3.968ProGly: 3.968 ± 1.724
4.63ProHis: 4.63 ± 2.095
5.952ProIle: 5.952 ± 2.277
3.968ProLys: 3.968 ± 1.292
2.646ProLeu: 2.646 ± 1.699
1.323ProMet: 1.323 ± 1.143
1.984ProAsn: 1.984 ± 0.763
3.307ProPro: 3.307 ± 1.832
4.63ProGln: 4.63 ± 1.813
2.646ProArg: 2.646 ± 1.249
4.63ProSer: 4.63 ± 2.264
2.646ProThr: 2.646 ± 1.633
2.646ProVal: 2.646 ± 0.873
1.984ProTrp: 1.984 ± 0.607
1.323ProTyr: 1.323 ± 0.653
0.0ProXaa: 0.0 ± 0.0
Gln
1.984GlnAla: 1.984 ± 0.952
1.984GlnCys: 1.984 ± 1.268
1.323GlnAsp: 1.323 ± 0.906
1.984GlnGlu: 1.984 ± 0.607
3.307GlnPhe: 3.307 ± 1.431
2.646GlnGly: 2.646 ± 1.811
2.646GlnHis: 2.646 ± 1.053
3.968GlnIle: 3.968 ± 2.271
0.661GlnLys: 0.661 ± 0.541
4.63GlnLeu: 4.63 ± 2.796
0.0GlnMet: 0.0 ± 0.0
1.984GlnAsn: 1.984 ± 1.135
3.968GlnPro: 3.968 ± 2.054
2.646GlnGln: 2.646 ± 1.225
4.63GlnArg: 4.63 ± 1.569
5.291GlnSer: 5.291 ± 2.27
0.661GlnThr: 0.661 ± 0.785
3.968GlnVal: 3.968 ± 1.335
1.323GlnTrp: 1.323 ± 1.082
1.323GlnTyr: 1.323 ± 0.823
0.0GlnXaa: 0.0 ± 0.0
Arg
3.968ArgAla: 3.968 ± 2.29
0.661ArgCys: 0.661 ± 0.573
3.968ArgAsp: 3.968 ± 1.49
1.323ArgGlu: 1.323 ± 0.832
7.275ArgPhe: 7.275 ± 1.609
3.307ArgGly: 3.307 ± 1.269
1.984ArgHis: 1.984 ± 1.049
4.63ArgIle: 4.63 ± 1.183
2.646ArgLys: 2.646 ± 0.879
3.968ArgLeu: 3.968 ± 1.216
1.323ArgMet: 1.323 ± 0.653
1.323ArgAsn: 1.323 ± 0.907
2.646ArgPro: 2.646 ± 1.211
1.984ArgGln: 1.984 ± 0.9
5.952ArgArg: 5.952 ± 3.067
8.598ArgSer: 8.598 ± 0.91
5.291ArgThr: 5.291 ± 2.129
3.968ArgVal: 3.968 ± 1.57
0.661ArgTrp: 0.661 ± 0.573
0.661ArgTyr: 0.661 ± 0.785
0.0ArgXaa: 0.0 ± 0.0
Ser
5.952SerAla: 5.952 ± 1.883
1.323SerCys: 1.323 ± 0.794
2.646SerAsp: 2.646 ± 0.54
1.323SerGlu: 1.323 ± 0.723
3.968SerPhe: 3.968 ± 1.001
1.984SerGly: 1.984 ± 1.084
2.646SerHis: 2.646 ± 1.698
4.63SerIle: 4.63 ± 2.425
5.952SerLys: 5.952 ± 1.481
6.614SerLeu: 6.614 ± 1.945
1.323SerMet: 1.323 ± 1.145
6.614SerAsn: 6.614 ± 1.647
5.291SerPro: 5.291 ± 3.296
4.63SerGln: 4.63 ± 2.05
6.614SerArg: 6.614 ± 1.848
11.243SerSer: 11.243 ± 3.352
8.598SerThr: 8.598 ± 3.425
5.952SerVal: 5.952 ± 1.588
1.323SerTrp: 1.323 ± 1.145
4.63SerTyr: 4.63 ± 1.885
0.0SerXaa: 0.0 ± 0.0
Thr
4.63ThrAla: 4.63 ± 1.704
0.661ThrCys: 0.661 ± 0.764
2.646ThrAsp: 2.646 ± 1.505
2.646ThrGlu: 2.646 ± 0.909
3.307ThrPhe: 3.307 ± 2.719
3.968ThrGly: 3.968 ± 1.315
5.952ThrHis: 5.952 ± 2.042
1.323ThrIle: 1.323 ± 0.723
0.661ThrLys: 0.661 ± 0.698
2.646ThrLeu: 2.646 ± 1.522
0.661ThrMet: 0.661 ± 0.573
3.968ThrAsn: 3.968 ± 1.11
3.307ThrPro: 3.307 ± 1.269
3.968ThrGln: 3.968 ± 1.959
3.968ThrArg: 3.968 ± 1.352
3.968ThrSer: 3.968 ± 2.289
3.307ThrThr: 3.307 ± 1.488
3.307ThrVal: 3.307 ± 0.874
0.661ThrTrp: 0.661 ± 0.764
1.984ThrTyr: 1.984 ± 1.178
0.0ThrXaa: 0.0 ± 0.0
Val
1.323ValAla: 1.323 ± 0.917
0.661ValCys: 0.661 ± 0.541
3.968ValAsp: 3.968 ± 1.818
3.968ValGlu: 3.968 ± 2.041
3.968ValPhe: 3.968 ± 2.374
3.307ValGly: 3.307 ± 1.214
1.984ValHis: 1.984 ± 0.9
3.968ValIle: 3.968 ± 1.611
4.63ValLys: 4.63 ± 1.516
3.307ValLeu: 3.307 ± 0.614
2.646ValMet: 2.646 ± 1.47
4.63ValAsn: 4.63 ± 1.648
3.968ValPro: 3.968 ± 0.672
3.307ValGln: 3.307 ± 1.704
2.646ValArg: 2.646 ± 0.941
3.968ValSer: 3.968 ± 1.178
3.307ValThr: 3.307 ± 1.224
3.307ValVal: 3.307 ± 2.754
1.323ValTrp: 1.323 ± 1.004
4.63ValTyr: 4.63 ± 2.613
0.0ValXaa: 0.0 ± 0.0
Trp
2.646TrpAla: 2.646 ± 1.225
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.323TrpGlu: 1.323 ± 0.815
0.0TrpPhe: 0.0 ± 0.0
0.661TrpGly: 0.661 ± 0.541
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.323TrpLys: 1.323 ± 0.653
0.661TrpLeu: 0.661 ± 0.571
1.323TrpMet: 1.323 ± 0.823
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.661TrpGln: 0.661 ± 0.541
1.323TrpArg: 1.323 ± 1.014
0.661TrpSer: 0.661 ± 0.698
1.323TrpThr: 1.323 ± 0.815
1.984TrpVal: 1.984 ± 0.996
0.0TrpTrp: 0.0 ± 0.0
1.323TrpTyr: 1.323 ± 0.832
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.307TyrAla: 3.307 ± 1.805
0.661TyrCys: 0.661 ± 0.698
1.323TyrAsp: 1.323 ± 0.823
0.661TyrGlu: 0.661 ± 0.571
1.984TyrPhe: 1.984 ± 0.607
2.646TyrGly: 2.646 ± 0.54
0.0TyrHis: 0.0 ± 0.0
3.968TyrIle: 3.968 ± 1.111
1.323TyrLys: 1.323 ± 0.788
3.968TyrLeu: 3.968 ± 1.964
1.323TyrMet: 1.323 ± 0.951
1.323TyrAsn: 1.323 ± 0.606
2.646TyrPro: 2.646 ± 1.378
1.323TyrGln: 1.323 ± 0.723
4.63TyrArg: 4.63 ± 2.142
2.646TyrSer: 2.646 ± 0.845
1.323TyrThr: 1.323 ± 1.088
2.646TyrVal: 2.646 ± 1.258
0.0TyrTrp: 0.0 ± 0.0
1.323TyrTyr: 1.323 ± 0.794
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1513 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski