Amino acid dipepetide frequency for Olleya namhaensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.004AlaAla: 4.004 ± 0.098	0.577AlaCys: 0.577 ± 0.027	3.431AlaAsp: 3.431 ± 0.073	3.942AlaGlu: 3.942 ± 0.076	3.588AlaPhe: 3.588 ± 0.055	3.881AlaGly: 3.881 ± 0.073	1.093AlaHis: 1.093 ± 0.03	5.808AlaIle: 5.808 ± 0.086	4.942AlaLys: 4.942 ± 0.087	6.889AlaLeu: 6.889 ± 0.104	1.469AlaMet: 1.469 ± 0.045	3.787AlaAsn: 3.787 ± 0.064	1.88AlaPro: 1.88 ± 0.053	2.451AlaGln: 2.451 ± 0.052	1.746AlaArg: 1.746 ± 0.045	4.378AlaSer: 4.378 ± 0.069	4.221AlaThr: 4.221 ± 0.093	4.078AlaVal: 4.078 ± 0.076	0.584AlaTrp: 0.584 ± 0.029	2.454AlaTyr: 2.454 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.46CysAla: 0.46 ± 0.029	0.081CysCys: 0.081 ± 0.008	0.561CysAsp: 0.561 ± 0.054	0.401CysGlu: 0.401 ± 0.021	0.421CysPhe: 0.421 ± 0.025	0.615CysGly: 0.615 ± 0.025	0.168CysHis: 0.168 ± 0.013	0.554CysIle: 0.554 ± 0.021	0.516CysLys: 0.516 ± 0.022	0.669CysLeu: 0.669 ± 0.024	0.12CysMet: 0.12 ± 0.011	0.477CysAsn: 0.477 ± 0.02	0.324CysPro: 0.324 ± 0.024	0.208CysGln: 0.208 ± 0.014	0.158CysArg: 0.158 ± 0.012	0.504CysSer: 0.504 ± 0.024	0.495CysThr: 0.495 ± 0.049	0.45CysVal: 0.45 ± 0.022	0.087CysTrp: 0.087 ± 0.021	0.371CysTyr: 0.371 ± 0.045	0.0CysXaa: 0.0 ± 0.0
Asp	4.39AspAla: 4.39 ± 0.075	0.496AspCys: 0.496 ± 0.034	3.316AspAsp: 3.316 ± 0.067	3.156AspGlu: 3.156 ± 0.06	3.678AspPhe: 3.678 ± 0.063	4.033AspGly: 4.033 ± 0.116	0.895AspHis: 0.895 ± 0.03	4.596AspIle: 4.596 ± 0.068	4.3AspLys: 4.3 ± 0.068	5.644AspLeu: 5.644 ± 0.083	1.088AspMet: 1.088 ± 0.037	4.016AspAsn: 4.016 ± 0.072	1.57AspPro: 1.57 ± 0.061	1.917AspGln: 1.917 ± 0.041	1.713AspArg: 1.713 ± 0.032	3.391AspSer: 3.391 ± 0.061	3.537AspThr: 3.537 ± 0.066	4.083AspVal: 4.083 ± 0.08	0.705AspTrp: 0.705 ± 0.027	3.073AspTyr: 3.073 ± 0.071	0.0AspXaa: 0.0 ± 0.0
Glu	4.683GluAla: 4.683 ± 0.079	0.393GluCys: 0.393 ± 0.047	4.062GluAsp: 4.062 ± 0.065	3.881GluGlu: 3.881 ± 0.083	2.722GluPhe: 2.722 ± 0.052	3.431GluGly: 3.431 ± 0.06	1.069GluHis: 1.069 ± 0.033	4.753GluIle: 4.753 ± 0.067	4.744GluLys: 4.744 ± 0.089	5.507GluLeu: 5.507 ± 0.079	1.235GluMet: 1.235 ± 0.031	4.115GluAsn: 4.115 ± 0.073	1.408GluPro: 1.408 ± 0.06	2.232GluGln: 2.232 ± 0.056	2.044GluArg: 2.044 ± 0.049	3.169GluSer: 3.169 ± 0.055	4.05GluThr: 4.05 ± 0.076	4.125GluVal: 4.125 ± 0.071	0.534GluTrp: 0.534 ± 0.027	2.114GluTyr: 2.114 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	2.99PheAla: 2.99 ± 0.058	0.444PheCys: 0.444 ± 0.019	3.422PheAsp: 3.422 ± 0.055	3.383PheGlu: 3.383 ± 0.056	2.656PhePhe: 2.656 ± 0.059	3.601PheGly: 3.601 ± 0.068	0.724PheHis: 0.724 ± 0.027	3.948PheIle: 3.948 ± 0.078	4.362PheLys: 4.362 ± 0.09	4.472PheLeu: 4.472 ± 0.083	1.035PheMet: 1.035 ± 0.039	3.754PheAsn: 3.754 ± 0.078	1.582PhePro: 1.582 ± 0.036	1.394PheGln: 1.394 ± 0.038	1.421PheArg: 1.421 ± 0.036	3.911PheSer: 3.911 ± 0.078	3.319PheThr: 3.319 ± 0.068	3.014PheVal: 3.014 ± 0.059	0.538PheTrp: 0.538 ± 0.023	2.187PheTyr: 2.187 ± 0.056	0.0PheXaa: 0.0 ± 0.0
Gly	4.011GlyAla: 4.011 ± 0.075	0.588GlyCys: 0.588 ± 0.026	3.62GlyAsp: 3.62 ± 0.073	3.177GlyGlu: 3.177 ± 0.067	3.645GlyPhe: 3.645 ± 0.061	4.12GlyGly: 4.12 ± 0.095	1.071GlyHis: 1.071 ± 0.038	4.815GlyIle: 4.815 ± 0.078	4.443GlyLys: 4.443 ± 0.083	5.847GlyLeu: 5.847 ± 0.092	1.378GlyMet: 1.378 ± 0.037	3.474GlyAsn: 3.474 ± 0.079	1.217GlyPro: 1.217 ± 0.036	2.042GlyGln: 2.042 ± 0.053	1.849GlyArg: 1.849 ± 0.048	3.841GlySer: 3.841 ± 0.063	4.279GlyThr: 4.279 ± 0.109	4.416GlyVal: 4.416 ± 0.07	0.656GlyTrp: 0.656 ± 0.026	2.663GlyTyr: 2.663 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	0.945HisAla: 0.945 ± 0.032	0.162HisCys: 0.162 ± 0.014	0.877HisAsp: 0.877 ± 0.031	0.843HisGlu: 0.843 ± 0.03	1.136HisPhe: 1.136 ± 0.033	0.928HisGly: 0.928 ± 0.034	0.41HisHis: 0.41 ± 0.02	1.317HisIle: 1.317 ± 0.038	1.202HisLys: 1.202 ± 0.036	1.758HisLeu: 1.758 ± 0.045	0.296HisMet: 0.296 ± 0.018	1.02HisAsn: 1.02 ± 0.035	0.779HisPro: 0.779 ± 0.027	0.634HisGln: 0.634 ± 0.025	0.527HisArg: 0.527 ± 0.022	0.958HisSer: 0.958 ± 0.028	0.938HisThr: 0.938 ± 0.031	0.982HisVal: 0.982 ± 0.033	0.201HisTrp: 0.201 ± 0.014	0.837HisTyr: 0.837 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.715IleAla: 5.715 ± 0.076	0.585IleCys: 0.585 ± 0.027	5.144IleAsp: 5.144 ± 0.075	5.398IleGlu: 5.398 ± 0.071	3.281IlePhe: 3.281 ± 0.069	4.996IleGly: 4.996 ± 0.087	1.208IleHis: 1.208 ± 0.042	6.389IleIle: 6.389 ± 0.096	6.302IleLys: 6.302 ± 0.095	6.996IleLeu: 6.996 ± 0.094	1.322IleMet: 1.322 ± 0.039	5.154IleAsn: 5.154 ± 0.078	3.047IlePro: 3.047 ± 0.052	2.47IleGln: 2.47 ± 0.046	2.14IleArg: 2.14 ± 0.05	5.35IleSer: 5.35 ± 0.093	5.582IleThr: 5.582 ± 0.094	5.003IleVal: 5.003 ± 0.076	0.591IleTrp: 0.591 ± 0.025	2.844IleTyr: 2.844 ± 0.064	0.0IleXaa: 0.0 ± 0.0
Lys	5.476LysAla: 5.476 ± 0.092	0.315LysCys: 0.315 ± 0.017	4.87LysAsp: 4.87 ± 0.08	5.28LysGlu: 5.28 ± 0.081	2.81LysPhe: 2.81 ± 0.064	4.315LysGly: 4.315 ± 0.074	1.611LysHis: 1.611 ± 0.044	5.97LysIle: 5.97 ± 0.088	6.528LysLys: 6.528 ± 0.101	6.86LysLeu: 6.86 ± 0.096	1.857LysMet: 1.857 ± 0.045	5.179LysAsn: 5.179 ± 0.082	2.529LysPro: 2.529 ± 0.051	3.4LysGln: 3.4 ± 0.064	2.76LysArg: 2.76 ± 0.06	4.772LysSer: 4.772 ± 0.082	5.567LysThr: 5.567 ± 0.105	4.537LysVal: 4.537 ± 0.072	0.746LysTrp: 0.746 ± 0.031	2.996LysTyr: 2.996 ± 0.056	0.0LysXaa: 0.0 ± 0.0
Leu	5.785LeuAla: 5.785 ± 0.089	0.671LeuCys: 0.671 ± 0.029	5.671LeuAsp: 5.671 ± 0.081	6.141LeuGlu: 6.141 ± 0.08	4.999LeuPhe: 4.999 ± 0.084	5.652LeuGly: 5.652 ± 0.087	1.482LeuHis: 1.482 ± 0.038	7.3LeuIle: 7.3 ± 0.117	8.317LeuLys: 8.317 ± 0.105	8.783LeuLeu: 8.783 ± 0.132	1.86LeuMet: 1.86 ± 0.051	6.039LeuAsn: 6.039 ± 0.1	3.359LeuPro: 3.359 ± 0.065	3.237LeuGln: 3.237 ± 0.056	2.791LeuArg: 2.791 ± 0.054	6.785LeuSer: 6.785 ± 0.091	5.427LeuThr: 5.427 ± 0.075	5.699LeuVal: 5.699 ± 0.085	0.718LeuTrp: 0.718 ± 0.025	3.175LeuTyr: 3.175 ± 0.058	0.0LeuXaa: 0.0 ± 0.0
Met	1.362MetAla: 1.362 ± 0.044	0.136MetCys: 0.136 ± 0.013	1.072MetAsp: 1.072 ± 0.034	1.192MetGlu: 1.192 ± 0.039	0.868MetPhe: 0.868 ± 0.031	1.077MetGly: 1.077 ± 0.034	0.356MetHis: 0.356 ± 0.019	1.368MetIle: 1.368 ± 0.04	1.891MetLys: 1.891 ± 0.042	1.884MetLeu: 1.884 ± 0.047	0.477MetMet: 0.477 ± 0.025	1.049MetAsn: 1.049 ± 0.029	0.754MetPro: 0.754 ± 0.03	0.848MetGln: 0.848 ± 0.03	0.76MetArg: 0.76 ± 0.025	1.432MetSer: 1.432 ± 0.04	1.187MetThr: 1.187 ± 0.038	1.274MetVal: 1.274 ± 0.04	0.149MetTrp: 0.149 ± 0.011	0.697MetTyr: 0.697 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	4.14AsnAla: 4.14 ± 0.064	0.508AsnCys: 0.508 ± 0.029	3.474AsnAsp: 3.474 ± 0.068	3.143AsnGlu: 3.143 ± 0.064	2.991AsnPhe: 2.991 ± 0.065	4.134AsnGly: 4.134 ± 0.082	1.053AsnHis: 1.053 ± 0.031	5.1AsnIle: 5.1 ± 0.077	4.769AsnLys: 4.769 ± 0.082	5.734AsnLeu: 5.734 ± 0.093	1.246AsnMet: 1.246 ± 0.028	4.763AsnAsn: 4.763 ± 0.114	2.689AsnPro: 2.689 ± 0.063	2.677AsnGln: 2.677 ± 0.052	1.995AsnArg: 1.995 ± 0.048	3.85AsnSer: 3.85 ± 0.075	4.97AsnThr: 4.97 ± 0.105	3.668AsnVal: 3.668 ± 0.059	0.742AsnTrp: 0.742 ± 0.028	3.202AsnTyr: 3.202 ± 0.071	0.0AsnXaa: 0.0 ± 0.0
Pro	1.816ProAla: 1.816 ± 0.066	0.206ProCys: 0.206 ± 0.014	1.89ProAsp: 1.89 ± 0.046	2.656ProGlu: 2.656 ± 0.048	1.828ProPhe: 1.828 ± 0.045	1.585ProGly: 1.585 ± 0.037	0.524ProHis: 0.524 ± 0.02	2.662ProIle: 2.662 ± 0.048	2.583ProLys: 2.583 ± 0.054	2.859ProLeu: 2.859 ± 0.06	0.649ProMet: 0.649 ± 0.026	2.264ProAsn: 2.264 ± 0.053	0.675ProPro: 0.675 ± 0.033	1.061ProGln: 1.061 ± 0.033	0.781ProArg: 0.781 ± 0.03	1.993ProSer: 1.993 ± 0.045	2.221ProThr: 2.221 ± 0.081	2.056ProVal: 2.056 ± 0.052	0.265ProTrp: 0.265 ± 0.015	1.237ProTyr: 1.237 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	2.12GlnAla: 2.12 ± 0.045	0.187GlnCys: 0.187 ± 0.013	2.077GlnAsp: 2.077 ± 0.046	2.175GlnGlu: 2.175 ± 0.051	1.975GlnPhe: 1.975 ± 0.047	1.721GlnGly: 1.721 ± 0.044	0.629GlnHis: 0.629 ± 0.024	2.764GlnIle: 2.764 ± 0.048	2.652GlnLys: 2.652 ± 0.055	3.86GlnLeu: 3.86 ± 0.065	0.788GlnMet: 0.788 ± 0.024	2.225GlnAsn: 2.225 ± 0.05	1.202GlnPro: 1.202 ± 0.046	1.478GlnGln: 1.478 ± 0.05	1.17GlnArg: 1.17 ± 0.034	2.145GlnSer: 2.145 ± 0.047	2.248GlnThr: 2.248 ± 0.048	2.147GlnVal: 2.147 ± 0.047	0.353GlnTrp: 0.353 ± 0.018	1.408GlnTyr: 1.408 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	1.954ArgAla: 1.954 ± 0.042	0.166ArgCys: 0.166 ± 0.013	1.606ArgAsp: 1.606 ± 0.038	1.789ArgGlu: 1.789 ± 0.046	1.758ArgPhe: 1.758 ± 0.035	1.719ArgGly: 1.719 ± 0.046	0.557ArgHis: 0.557 ± 0.023	2.454ArgIle: 2.454 ± 0.05	2.308ArgLys: 2.308 ± 0.053	3.0ArgLeu: 3.0 ± 0.064	0.677ArgMet: 0.677 ± 0.024	1.775ArgAsn: 1.775 ± 0.042	0.962ArgPro: 0.962 ± 0.039	1.113ArgGln: 1.113 ± 0.033	1.135ArgArg: 1.135 ± 0.035	1.645ArgSer: 1.645 ± 0.043	1.679ArgThr: 1.679 ± 0.048	1.965ArgVal: 1.965 ± 0.053	0.306ArgTrp: 0.306 ± 0.017	1.361ArgTyr: 1.361 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	3.997SerAla: 3.997 ± 0.069	0.672SerCys: 0.672 ± 0.032	3.801SerAsp: 3.801 ± 0.054	3.748SerGlu: 3.748 ± 0.056	3.696SerPhe: 3.696 ± 0.063	4.625SerGly: 4.625 ± 0.088	1.054SerHis: 1.054 ± 0.03	5.208SerIle: 5.208 ± 0.079	5.316SerLys: 5.316 ± 0.075	5.674SerLeu: 5.674 ± 0.085	1.125SerMet: 1.125 ± 0.032	4.209SerAsn: 4.209 ± 0.084	1.94SerPro: 1.94 ± 0.052	2.326SerGln: 2.326 ± 0.044	1.886SerArg: 1.886 ± 0.046	3.989SerSer: 3.989 ± 0.077	3.901SerThr: 3.901 ± 0.072	4.011SerVal: 4.011 ± 0.054	0.618SerTrp: 0.618 ± 0.021	2.731SerTyr: 2.731 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	4.155ThrAla: 4.155 ± 0.087	0.486ThrCys: 0.486 ± 0.048	3.888ThrAsp: 3.888 ± 0.084	3.96ThrGlu: 3.96 ± 0.079	3.461ThrPhe: 3.461 ± 0.084	4.025ThrGly: 4.025 ± 0.087	1.007ThrHis: 1.007 ± 0.032	5.914ThrIle: 5.914 ± 0.102	4.583ThrLys: 4.583 ± 0.075	6.234ThrLeu: 6.234 ± 0.085	1.013ThrMet: 1.013 ± 0.031	4.072ThrAsn: 4.072 ± 0.08	2.505ThrPro: 2.505 ± 0.053	2.19ThrGln: 2.19 ± 0.054	1.615ThrArg: 1.615 ± 0.04	4.398ThrSer: 4.398 ± 0.075	4.884ThrThr: 4.884 ± 0.148	4.413ThrVal: 4.413 ± 0.089	0.669ThrTrp: 0.669 ± 0.058	2.563ThrTyr: 2.563 ± 0.064	0.0ThrXaa: 0.0 ± 0.0
Val	4.267ValAla: 4.267 ± 0.073	0.519ValCys: 0.519 ± 0.025	3.768ValAsp: 3.768 ± 0.072	3.62ValGlu: 3.62 ± 0.064	3.647ValPhe: 3.647 ± 0.067	3.802ValGly: 3.802 ± 0.076	0.881ValHis: 0.881 ± 0.038	5.113ValIle: 5.113 ± 0.075	4.594ValLys: 4.594 ± 0.08	6.422ValLeu: 6.422 ± 0.083	1.239ValMet: 1.239 ± 0.031	3.712ValAsn: 3.712 ± 0.055	1.904ValPro: 1.904 ± 0.049	1.68ValGln: 1.68 ± 0.042	1.747ValArg: 1.747 ± 0.038	4.649ValSer: 4.649 ± 0.066	4.294ValThr: 4.294 ± 0.096	4.352ValVal: 4.352 ± 0.091	0.566ValTrp: 0.566 ± 0.024	2.297ValTyr: 2.297 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.532TrpAla: 0.532 ± 0.023	0.095TrpCys: 0.095 ± 0.009	0.656TrpAsp: 0.656 ± 0.049	0.56TrpGlu: 0.56 ± 0.031	0.531TrpPhe: 0.531 ± 0.024	0.489TrpGly: 0.489 ± 0.028	0.184TrpHis: 0.184 ± 0.014	0.687TrpIle: 0.687 ± 0.029	0.715TrpLys: 0.715 ± 0.025	0.976TrpLeu: 0.976 ± 0.038	0.267TrpMet: 0.267 ± 0.018	0.658TrpAsn: 0.658 ± 0.028	0.175TrpPro: 0.175 ± 0.013	0.385TrpGln: 0.385 ± 0.019	0.344TrpArg: 0.344 ± 0.019	0.668TrpSer: 0.668 ± 0.026	0.573TrpThr: 0.573 ± 0.024	0.57TrpVal: 0.57 ± 0.025	0.124TrpTrp: 0.124 ± 0.012	0.409TrpTyr: 0.409 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.399TyrAla: 2.399 ± 0.052	0.353TyrCys: 0.353 ± 0.02	2.39TyrAsp: 2.39 ± 0.06	1.828TyrGlu: 1.828 ± 0.06	2.465TyrPhe: 2.465 ± 0.053	2.402TyrGly: 2.402 ± 0.054	0.774TyrHis: 0.774 ± 0.029	2.796TyrIle: 2.796 ± 0.055	3.314TyrLys: 3.314 ± 0.067	3.823TyrLeu: 3.823 ± 0.079	0.69TyrMet: 0.69 ± 0.026	3.104TyrAsn: 3.104 ± 0.073	1.31TyrPro: 1.31 ± 0.034	1.582TyrGln: 1.582 ± 0.039	1.349TyrArg: 1.349 ± 0.04	2.701TyrSer: 2.701 ± 0.065	2.663TyrThr: 2.663 ± 0.067	2.23TyrVal: 2.23 ± 0.05	0.445TyrTrp: 0.445 ± 0.022	1.844TyrTyr: 1.844 ± 0.057	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3170 proteins (1067814 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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