Amino acid dipepetide frequency for Celerinatantimonas diazotrophica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.486AlaAla: 7.486 ± 0.1	1.051AlaCys: 1.051 ± 0.035	4.293AlaAsp: 4.293 ± 0.073	4.371AlaGlu: 4.371 ± 0.063	3.192AlaPhe: 3.192 ± 0.052	5.884AlaGly: 5.884 ± 0.086	2.108AlaHis: 2.108 ± 0.046	6.41AlaIle: 6.41 ± 0.087	5.028AlaLys: 5.028 ± 0.086	10.252AlaLeu: 10.252 ± 0.113	2.76AlaMet: 2.76 ± 0.049	3.551AlaAsn: 3.551 ± 0.066	2.96AlaPro: 2.96 ± 0.061	5.093AlaGln: 5.093 ± 0.073	4.03AlaArg: 4.03 ± 0.062	5.278AlaSer: 5.278 ± 0.076	4.341AlaThr: 4.341 ± 0.073	5.645AlaVal: 5.645 ± 0.081	0.946AlaTrp: 0.946 ± 0.035	2.34AlaTyr: 2.34 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.964CysAla: 0.964 ± 0.031	0.221CysCys: 0.221 ± 0.016	0.654CysAsp: 0.654 ± 0.027	0.704CysGlu: 0.704 ± 0.028	0.505CysPhe: 0.505 ± 0.022	1.042CysGly: 1.042 ± 0.029	0.436CysHis: 0.436 ± 0.021	0.666CysIle: 0.666 ± 0.023	0.363CysLys: 0.363 ± 0.02	1.154CysLeu: 1.154 ± 0.035	0.281CysMet: 0.281 ± 0.015	0.385CysAsn: 0.385 ± 0.017	0.546CysPro: 0.546 ± 0.02	0.812CysGln: 0.812 ± 0.03	0.545CysArg: 0.545 ± 0.022	0.774CysSer: 0.774 ± 0.024	0.391CysThr: 0.391 ± 0.02	0.765CysVal: 0.765 ± 0.027	0.174CysTrp: 0.174 ± 0.013	0.44CysTyr: 0.44 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	4.1AspAla: 4.1 ± 0.065	0.553AspCys: 0.553 ± 0.021	2.917AspAsp: 2.917 ± 0.061	3.743AspGlu: 3.743 ± 0.075	2.182AspPhe: 2.182 ± 0.043	3.385AspGly: 3.385 ± 0.066	1.266AspHis: 1.266 ± 0.035	3.587AspIle: 3.587 ± 0.057	2.664AspLys: 2.664 ± 0.052	4.792AspLeu: 4.792 ± 0.069	1.252AspMet: 1.252 ± 0.035	2.08AspAsn: 2.08 ± 0.052	2.248AspPro: 2.248 ± 0.047	2.188AspGln: 2.188 ± 0.049	2.092AspArg: 2.092 ± 0.044	3.16AspSer: 3.16 ± 0.055	2.156AspThr: 2.156 ± 0.044	3.454AspVal: 3.454 ± 0.055	0.857AspTrp: 0.857 ± 0.025	2.029AspTyr: 2.029 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	4.151GluAla: 4.151 ± 0.061	0.545GluCys: 0.545 ± 0.025	2.21GluAsp: 2.21 ± 0.05	2.662GluGlu: 2.662 ± 0.068	2.158GluPhe: 2.158 ± 0.046	2.756GluGly: 2.756 ± 0.051	1.757GluHis: 1.757 ± 0.049	3.313GluIle: 3.313 ± 0.058	3.047GluLys: 3.047 ± 0.061	6.617GluLeu: 6.617 ± 0.098	1.39GluMet: 1.39 ± 0.033	2.333GluAsn: 2.333 ± 0.048	2.141GluPro: 2.141 ± 0.051	4.982GluGln: 4.982 ± 0.091	3.126GluArg: 3.126 ± 0.054	2.99GluSer: 2.99 ± 0.051	2.435GluThr: 2.435 ± 0.057	3.527GluVal: 3.527 ± 0.059	0.496GluTrp: 0.496 ± 0.023	1.578GluTyr: 1.578 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	3.774PheAla: 3.774 ± 0.061	0.576PheCys: 0.576 ± 0.025	2.444PheAsp: 2.444 ± 0.051	2.041PheGlu: 2.041 ± 0.045	1.766PhePhe: 1.766 ± 0.048	3.077PheGly: 3.077 ± 0.062	1.003PheHis: 1.003 ± 0.034	3.081PheIle: 3.081 ± 0.06	1.959PheLys: 1.959 ± 0.04	3.494PheLeu: 3.494 ± 0.062	0.972PheMet: 0.972 ± 0.028	1.942PheAsn: 1.942 ± 0.041	1.349PhePro: 1.349 ± 0.034	1.277PheGln: 1.277 ± 0.029	1.564PheArg: 1.564 ± 0.035	3.22PheSer: 3.22 ± 0.064	2.15PheThr: 2.15 ± 0.051	2.656PheVal: 2.656 ± 0.057	0.555PheTrp: 0.555 ± 0.023	1.444PheTyr: 1.444 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.233GlyAla: 5.233 ± 0.087	1.037GlyCys: 1.037 ± 0.031	3.162GlyAsp: 3.162 ± 0.059	3.602GlyGlu: 3.602 ± 0.058	3.263GlyPhe: 3.263 ± 0.053	4.5GlyGly: 4.5 ± 0.078	1.813GlyHis: 1.813 ± 0.044	4.941GlyIle: 4.941 ± 0.066	3.678GlyLys: 3.678 ± 0.062	6.839GlyLeu: 6.839 ± 0.085	1.978GlyMet: 1.978 ± 0.045	2.348GlyAsn: 2.348 ± 0.053	1.88GlyPro: 1.88 ± 0.042	3.507GlyGln: 3.507 ± 0.057	3.097GlyArg: 3.097 ± 0.053	4.095GlySer: 4.095 ± 0.073	3.122GlyThr: 3.122 ± 0.072	4.904GlyVal: 4.904 ± 0.073	1.004GlyTrp: 1.004 ± 0.033	2.714GlyTyr: 2.714 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	1.815HisAla: 1.815 ± 0.037	0.422HisCys: 0.422 ± 0.02	1.243HisAsp: 1.243 ± 0.034	1.225HisGlu: 1.225 ± 0.033	1.229HisPhe: 1.229 ± 0.033	1.708HisGly: 1.708 ± 0.042	1.031HisHis: 1.031 ± 0.031	1.662HisIle: 1.662 ± 0.042	1.026HisLys: 1.026 ± 0.033	2.756HisLeu: 2.756 ± 0.057	0.581HisMet: 0.581 ± 0.025	0.997HisAsn: 0.997 ± 0.031	1.551HisPro: 1.551 ± 0.041	1.862HisGln: 1.862 ± 0.04	1.351HisArg: 1.351 ± 0.034	1.678HisSer: 1.678 ± 0.043	1.107HisThr: 1.107 ± 0.03	1.374HisVal: 1.374 ± 0.035	0.573HisTrp: 0.573 ± 0.021	1.221HisTyr: 1.221 ± 0.037	0.0HisXaa: 0.0 ± 0.0
Ile	7.045IleAla: 7.045 ± 0.082	0.848IleCys: 0.848 ± 0.023	4.157IleAsp: 4.157 ± 0.061	4.396IleGlu: 4.396 ± 0.068	2.55IlePhe: 2.55 ± 0.056	5.0IleGly: 5.0 ± 0.08	1.646IleHis: 1.646 ± 0.038	4.2IleIle: 4.2 ± 0.075	3.186IleLys: 3.186 ± 0.058	5.799IleLeu: 5.799 ± 0.082	1.351IleMet: 1.351 ± 0.041	2.991IleAsn: 2.991 ± 0.062	2.733IlePro: 2.733 ± 0.051	2.587IleGln: 2.587 ± 0.053	3.186IleArg: 3.186 ± 0.06	4.559IleSer: 4.559 ± 0.072	3.489IleThr: 3.489 ± 0.057	4.272IleVal: 4.272 ± 0.069	0.781IleTrp: 0.781 ± 0.029	1.968IleTyr: 1.968 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	4.734LysAla: 4.734 ± 0.091	0.32LysCys: 0.32 ± 0.02	2.364LysAsp: 2.364 ± 0.043	2.767LysGlu: 2.767 ± 0.065	1.433LysPhe: 1.433 ± 0.037	2.955LysGly: 2.955 ± 0.056	1.115LysHis: 1.115 ± 0.035	3.061LysIle: 3.061 ± 0.061	2.638LysLys: 2.638 ± 0.058	5.401LysLeu: 5.401 ± 0.075	1.356LysMet: 1.356 ± 0.043	2.078LysAsn: 2.078 ± 0.053	2.266LysPro: 2.266 ± 0.05	2.903LysGln: 2.903 ± 0.055	2.687LysArg: 2.687 ± 0.049	2.977LysSer: 2.977 ± 0.052	2.727LysThr: 2.727 ± 0.055	3.583LysVal: 3.583 ± 0.06	0.548LysTrp: 0.548 ± 0.022	1.329LysTyr: 1.329 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	10.647LeuAla: 10.647 ± 0.111	1.392LeuCys: 1.392 ± 0.042	5.537LeuAsp: 5.537 ± 0.094	5.545LeuGlu: 5.545 ± 0.09	4.308LeuPhe: 4.308 ± 0.063	7.242LeuGly: 7.242 ± 0.091	2.304LeuHis: 2.304 ± 0.051	6.836LeuIle: 6.836 ± 0.098	5.79LeuLys: 5.79 ± 0.075	11.587LeuLeu: 11.587 ± 0.126	2.782LeuMet: 2.782 ± 0.057	4.98LeuAsn: 4.98 ± 0.067	4.897LeuPro: 4.897 ± 0.072	4.071LeuGln: 4.071 ± 0.07	4.792LeuArg: 4.792 ± 0.069	8.501LeuSer: 8.501 ± 0.098	6.0LeuThr: 6.0 ± 0.075	7.02LeuVal: 7.02 ± 0.078	1.245LeuTrp: 1.245 ± 0.04	2.81LeuTyr: 2.81 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	2.656MetAla: 2.656 ± 0.046	0.195MetCys: 0.195 ± 0.012	1.162MetAsp: 1.162 ± 0.03	1.064MetGlu: 1.064 ± 0.031	0.853MetPhe: 0.853 ± 0.028	1.742MetGly: 1.742 ± 0.037	0.591MetHis: 0.591 ± 0.023	1.686MetIle: 1.686 ± 0.04	1.293MetLys: 1.293 ± 0.036	2.883MetLeu: 2.883 ± 0.049	0.758MetMet: 0.758 ± 0.027	1.162MetAsn: 1.162 ± 0.033	1.213MetPro: 1.213 ± 0.033	1.387MetGln: 1.387 ± 0.037	1.305MetArg: 1.305 ± 0.037	1.898MetSer: 1.898 ± 0.043	1.551MetThr: 1.551 ± 0.037	1.834MetVal: 1.834 ± 0.041	0.193MetTrp: 0.193 ± 0.012	0.532MetTyr: 0.532 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.358AsnAla: 3.358 ± 0.06	0.465AsnCys: 0.465 ± 0.021	2.128AsnAsp: 2.128 ± 0.051	2.239AsnGlu: 2.239 ± 0.049	1.501AsnPhe: 1.501 ± 0.032	2.757AsnGly: 2.757 ± 0.06	1.241AsnHis: 1.241 ± 0.034	2.853AsnIle: 2.853 ± 0.063	1.977AsnLys: 1.977 ± 0.049	3.898AsnLeu: 3.898 ± 0.058	1.011AsnMet: 1.011 ± 0.03	1.77AsnAsn: 1.77 ± 0.046	2.115AsnPro: 2.115 ± 0.035	2.519AsnGln: 2.519 ± 0.044	2.07AsnArg: 2.07 ± 0.046	2.43AsnSer: 2.43 ± 0.051	1.932AsnThr: 1.932 ± 0.055	2.5AsnVal: 2.5 ± 0.052	0.697AsnTrp: 0.697 ± 0.024	1.393AsnTyr: 1.393 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	3.229ProAla: 3.229 ± 0.062	0.404ProCys: 0.404 ± 0.019	2.358ProAsp: 2.358 ± 0.047	2.78ProGlu: 2.78 ± 0.047	1.718ProPhe: 1.718 ± 0.043	2.558ProGly: 2.558 ± 0.056	0.997ProHis: 0.997 ± 0.032	2.661ProIle: 2.661 ± 0.048	2.215ProLys: 2.215 ± 0.049	4.445ProLeu: 4.445 ± 0.074	1.067ProMet: 1.067 ± 0.034	1.758ProAsn: 1.758 ± 0.035	1.302ProPro: 1.302 ± 0.039	2.181ProGln: 2.181 ± 0.05	1.514ProArg: 1.514 ± 0.032	2.614ProSer: 2.614 ± 0.051	2.142ProThr: 2.142 ± 0.044	2.974ProVal: 2.974 ± 0.063	0.602ProTrp: 0.602 ± 0.024	1.389ProTyr: 1.389 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	4.966GlnAla: 4.966 ± 0.065	0.554GlnCys: 0.554 ± 0.026	1.937GlnAsp: 1.937 ± 0.046	2.326GlnGlu: 2.326 ± 0.058	2.116GlnPhe: 2.116 ± 0.042	3.39GlnGly: 3.39 ± 0.066	1.484GlnHis: 1.484 ± 0.043	3.509GlnIle: 3.509 ± 0.06	2.251GlnLys: 2.251 ± 0.05	7.334GlnLeu: 7.334 ± 0.136	1.492GlnMet: 1.492 ± 0.036	1.906GlnAsn: 1.906 ± 0.047	2.169GlnPro: 2.169 ± 0.048	4.171GlnGln: 4.171 ± 0.107	3.018GlnArg: 3.018 ± 0.061	3.823GlnSer: 3.823 ± 0.058	2.835GlnThr: 2.835 ± 0.057	3.617GlnVal: 3.617 ± 0.059	0.938GlnTrp: 0.938 ± 0.033	1.538GlnTyr: 1.538 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	3.64ArgAla: 3.64 ± 0.055	0.613ArgCys: 0.613 ± 0.024	2.38ArgAsp: 2.38 ± 0.05	2.891ArgGlu: 2.891 ± 0.055	2.251ArgPhe: 2.251 ± 0.047	2.676ArgGly: 2.676 ± 0.05	1.473ArgHis: 1.473 ± 0.041	3.103ArgIle: 3.103 ± 0.062	2.227ArgLys: 2.227 ± 0.047	5.448ArgLeu: 5.448 ± 0.072	1.201ArgMet: 1.201 ± 0.034	1.78ArgAsn: 1.78 ± 0.04	1.77ArgPro: 1.77 ± 0.038	3.104ArgGln: 3.104 ± 0.066	2.753ArgArg: 2.753 ± 0.059	3.0ArgSer: 3.0 ± 0.056	1.99ArgThr: 1.99 ± 0.043	3.081ArgVal: 3.081 ± 0.064	0.767ArgTrp: 0.767 ± 0.026	2.095ArgTyr: 2.095 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	5.745SerAla: 5.745 ± 0.082	0.741SerCys: 0.741 ± 0.029	3.603SerAsp: 3.603 ± 0.057	3.829SerGlu: 3.829 ± 0.068	2.847SerPhe: 2.847 ± 0.056	5.014SerGly: 5.014 ± 0.09	1.844SerHis: 1.844 ± 0.04	4.119SerIle: 4.119 ± 0.064	2.93SerLys: 2.93 ± 0.048	7.155SerLeu: 7.155 ± 0.096	1.709SerMet: 1.709 ± 0.039	2.486SerAsn: 2.486 ± 0.045	2.508SerPro: 2.508 ± 0.046	3.653SerGln: 3.653 ± 0.054	3.088SerArg: 3.088 ± 0.052	4.588SerSer: 4.588 ± 0.077	2.936SerThr: 2.936 ± 0.055	4.344SerVal: 4.344 ± 0.063	0.97SerTrp: 0.97 ± 0.027	2.108SerTyr: 2.108 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	4.04ThrAla: 4.04 ± 0.069	0.452ThrCys: 0.452 ± 0.021	2.553ThrAsp: 2.553 ± 0.054	2.449ThrGlu: 2.449 ± 0.045	1.844ThrPhe: 1.844 ± 0.041	3.712ThrGly: 3.712 ± 0.081	1.463ThrHis: 1.463 ± 0.036	3.437ThrIle: 3.437 ± 0.053	1.999ThrLys: 1.999 ± 0.046	6.056ThrLeu: 6.056 ± 0.092	1.143ThrMet: 1.143 ± 0.033	1.843ThrAsn: 1.843 ± 0.043	2.57ThrPro: 2.57 ± 0.051	2.753ThrGln: 2.753 ± 0.05	2.405ThrArg: 2.405 ± 0.052	3.1ThrSer: 3.1 ± 0.068	2.706ThrThr: 2.706 ± 0.058	3.209ThrVal: 3.209 ± 0.061	0.546ThrTrp: 0.546 ± 0.021	1.384ThrTyr: 1.384 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	6.203ValAla: 6.203 ± 0.079	0.814ValCys: 0.814 ± 0.028	3.583ValAsp: 3.583 ± 0.06	3.656ValGlu: 3.656 ± 0.068	2.561ValPhe: 2.561 ± 0.051	4.495ValGly: 4.495 ± 0.075	1.459ValHis: 1.459 ± 0.041	5.051ValIle: 5.051 ± 0.077	3.284ValLys: 3.284 ± 0.053	6.592ValLeu: 6.592 ± 0.09	1.89ValMet: 1.89 ± 0.04	2.875ValAsn: 2.875 ± 0.057	2.485ValPro: 2.485 ± 0.046	2.439ValGln: 2.439 ± 0.047	2.938ValArg: 2.938 ± 0.055	4.736ValSer: 4.736 ± 0.07	3.789ValThr: 3.789 ± 0.08	5.073ValVal: 5.073 ± 0.079	0.648ValTrp: 0.648 ± 0.022	1.821ValTyr: 1.821 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.896TrpAla: 0.896 ± 0.031	0.172TrpCys: 0.172 ± 0.011	0.574TrpAsp: 0.574 ± 0.023	0.479TrpGlu: 0.479 ± 0.021	0.634TrpPhe: 0.634 ± 0.025	0.762TrpGly: 0.762 ± 0.027	0.434TrpHis: 0.434 ± 0.02	0.775TrpIle: 0.775 ± 0.028	0.461TrpLys: 0.461 ± 0.022	2.083TrpLeu: 2.083 ± 0.047	0.339TrpMet: 0.339 ± 0.018	0.428TrpAsn: 0.428 ± 0.019	0.611TrpPro: 0.611 ± 0.025	1.293TrpGln: 1.293 ± 0.041	0.721TrpArg: 0.721 ± 0.029	0.721TrpSer: 0.721 ± 0.027	0.469TrpThr: 0.469 ± 0.021	0.873TrpVal: 0.873 ± 0.027	0.204TrpTrp: 0.204 ± 0.017	0.37TrpTyr: 0.37 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.337TyrAla: 2.337 ± 0.047	0.447TyrCys: 0.447 ± 0.018	1.445TyrAsp: 1.445 ± 0.039	1.443TyrGlu: 1.443 ± 0.041	1.431TyrPhe: 1.431 ± 0.034	2.063TyrGly: 2.063 ± 0.042	0.945TyrHis: 0.945 ± 0.032	1.795TyrIle: 1.795 ± 0.045	1.223TyrLys: 1.223 ± 0.033	3.703TyrLeu: 3.703 ± 0.062	0.645TyrMet: 0.645 ± 0.023	1.161TyrAsn: 1.161 ± 0.034	1.594TyrPro: 1.594 ± 0.037	2.591TyrGln: 2.591 ± 0.057	1.964TyrArg: 1.964 ± 0.043	2.076TyrSer: 2.076 ± 0.049	1.397TyrThr: 1.397 ± 0.035	1.688TyrVal: 1.688 ± 0.04	0.557TyrTrp: 0.557 ± 0.022	1.093TyrTyr: 1.093 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3525 proteins (1124885 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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