Amino acid dipepetide frequency for Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.205AlaAla: 5.205 ± 0.084	0.956AlaCys: 0.956 ± 0.027	3.95AlaAsp: 3.95 ± 0.055	4.413AlaGlu: 4.413 ± 0.068	3.313AlaPhe: 3.313 ± 0.054	5.127AlaGly: 5.127 ± 0.065	1.111AlaHis: 1.111 ± 0.029	4.887AlaIle: 4.887 ± 0.073	4.091AlaLys: 4.091 ± 0.063	6.739AlaLeu: 6.739 ± 0.078	1.878AlaMet: 1.878 ± 0.035	3.232AlaAsn: 3.232 ± 0.049	2.311AlaPro: 2.311 ± 0.041	2.47AlaGln: 2.47 ± 0.043	3.053AlaArg: 3.053 ± 0.042	4.609AlaSer: 4.609 ± 0.057	3.77AlaThr: 3.77 ± 0.062	4.517AlaVal: 4.517 ± 0.065	0.875AlaTrp: 0.875 ± 0.026	3.005AlaTyr: 3.005 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.739CysAla: 0.739 ± 0.025	0.211CysCys: 0.211 ± 0.014	0.619CysAsp: 0.619 ± 0.019	0.672CysGlu: 0.672 ± 0.021	0.625CysPhe: 0.625 ± 0.023	0.986CysGly: 0.986 ± 0.03	0.279CysHis: 0.279 ± 0.014	0.823CysIle: 0.823 ± 0.03	0.632CysLys: 0.632 ± 0.02	1.154CysLeu: 1.154 ± 0.026	0.355CysMet: 0.355 ± 0.017	0.483CysAsn: 0.483 ± 0.02	0.531CysPro: 0.531 ± 0.021	0.307CysGln: 0.307 ± 0.018	0.556CysArg: 0.556 ± 0.02	0.764CysSer: 0.764 ± 0.023	0.599CysThr: 0.599 ± 0.02	0.787CysVal: 0.787 ± 0.027	0.171CysTrp: 0.171 ± 0.012	0.497CysTyr: 0.497 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.773AspAla: 3.773 ± 0.062	0.584AspCys: 0.584 ± 0.021	2.546AspAsp: 2.546 ± 0.051	3.752AspGlu: 3.752 ± 0.053	2.936AspPhe: 2.936 ± 0.051	3.928AspGly: 3.928 ± 0.062	0.943AspHis: 0.943 ± 0.024	4.183AspIle: 4.183 ± 0.052	3.953AspLys: 3.953 ± 0.059	5.218AspLeu: 5.218 ± 0.065	1.671AspMet: 1.671 ± 0.029	2.627AspAsn: 2.627 ± 0.044	2.235AspPro: 2.235 ± 0.046	1.524AspGln: 1.524 ± 0.03	2.619AspArg: 2.619 ± 0.045	3.074AspSer: 3.074 ± 0.046	2.795AspThr: 2.795 ± 0.047	3.46AspVal: 3.46 ± 0.057	0.9AspTrp: 0.9 ± 0.026	2.88AspTyr: 2.88 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	5.007GluAla: 5.007 ± 0.067	0.586GluCys: 0.586 ± 0.022	3.385GluAsp: 3.385 ± 0.054	5.083GluGlu: 5.083 ± 0.079	2.338GluPhe: 2.338 ± 0.041	4.175GluGly: 4.175 ± 0.059	1.125GluHis: 1.125 ± 0.029	4.692GluIle: 4.692 ± 0.066	5.023GluLys: 5.023 ± 0.075	5.906GluLeu: 5.906 ± 0.075	1.888GluMet: 1.888 ± 0.037	3.603GluAsn: 3.603 ± 0.049	1.842GluPro: 1.842 ± 0.042	2.436GluGln: 2.436 ± 0.048	3.473GluArg: 3.473 ± 0.061	3.321GluSer: 3.321 ± 0.051	3.179GluThr: 3.179 ± 0.048	4.432GluVal: 4.432 ± 0.063	0.821GluTrp: 0.821 ± 0.026	2.703GluTyr: 2.703 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.091PheAla: 3.091 ± 0.051	0.656PheCys: 0.656 ± 0.026	2.784PheAsp: 2.784 ± 0.047	2.52PheGlu: 2.52 ± 0.045	2.28PhePhe: 2.28 ± 0.053	3.275PheGly: 3.275 ± 0.055	0.897PheHis: 0.897 ± 0.023	3.268PheIle: 3.268 ± 0.061	2.57PheLys: 2.57 ± 0.046	4.284PheLeu: 4.284 ± 0.065	1.342PheMet: 1.342 ± 0.031	2.44PheAsn: 2.44 ± 0.047	1.884PhePro: 1.884 ± 0.037	1.305PheGln: 1.305 ± 0.034	2.108PheArg: 2.108 ± 0.04	3.557PheSer: 3.557 ± 0.065	2.855PheThr: 2.855 ± 0.044	3.016PheVal: 3.016 ± 0.053	0.586PheTrp: 0.586 ± 0.021	2.011PheTyr: 2.011 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	4.396GlyAla: 4.396 ± 0.065	0.887GlyCys: 0.887 ± 0.027	3.626GlyAsp: 3.626 ± 0.052	4.234GlyGlu: 4.234 ± 0.059	3.306GlyPhe: 3.306 ± 0.057	4.814GlyGly: 4.814 ± 0.078	1.209GlyHis: 1.209 ± 0.03	5.312GlyIle: 5.312 ± 0.072	5.246GlyLys: 5.246 ± 0.071	6.115GlyLeu: 6.115 ± 0.074	2.155GlyMet: 2.155 ± 0.04	3.455GlyAsn: 3.455 ± 0.062	1.367GlyPro: 1.367 ± 0.035	2.061GlyGln: 2.061 ± 0.039	2.925GlyArg: 2.925 ± 0.05	4.123GlySer: 4.123 ± 0.065	4.156GlyThr: 4.156 ± 0.052	4.824GlyVal: 4.824 ± 0.069	0.993GlyTrp: 0.993 ± 0.03	3.421GlyTyr: 3.421 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.135HisAla: 1.135 ± 0.026	0.282HisCys: 0.282 ± 0.013	0.868HisAsp: 0.868 ± 0.028	1.02HisGlu: 1.02 ± 0.027	1.02HisPhe: 1.02 ± 0.027	1.158HisGly: 1.158 ± 0.03	0.437HisHis: 0.437 ± 0.019	1.414HisIle: 1.414 ± 0.034	1.031HisLys: 1.031 ± 0.027	1.777HisLeu: 1.777 ± 0.039	0.409HisMet: 0.409 ± 0.018	0.845HisAsn: 0.845 ± 0.022	1.036HisPro: 1.036 ± 0.028	0.556HisGln: 0.556 ± 0.019	0.825HisArg: 0.825 ± 0.024	1.095HisSer: 1.095 ± 0.028	1.043HisThr: 1.043 ± 0.028	1.027HisVal: 1.027 ± 0.027	0.246HisTrp: 0.246 ± 0.014	0.824HisTyr: 0.824 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.331IleAla: 5.331 ± 0.074	0.991IleCys: 0.991 ± 0.028	4.154IleAsp: 4.154 ± 0.057	4.457IleGlu: 4.457 ± 0.054	2.781IlePhe: 2.781 ± 0.052	4.809IleGly: 4.809 ± 0.08	1.479IleHis: 1.479 ± 0.034	4.364IleIle: 4.364 ± 0.069	4.072IleLys: 4.072 ± 0.059	6.247IleLeu: 6.247 ± 0.083	1.568IleMet: 1.568 ± 0.032	3.243IleAsn: 3.243 ± 0.05	3.363IlePro: 3.363 ± 0.048	2.457IleGln: 2.457 ± 0.041	3.679IleArg: 3.679 ± 0.055	4.809IleSer: 4.809 ± 0.06	4.023IleThr: 4.023 ± 0.06	4.448IleVal: 4.448 ± 0.068	0.724IleTrp: 0.724 ± 0.024	2.826IleTyr: 2.826 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	4.793LysAla: 4.793 ± 0.069	0.53LysCys: 0.53 ± 0.021	4.128LysAsp: 4.128 ± 0.064	5.768LysGlu: 5.768 ± 0.079	2.057LysPhe: 2.057 ± 0.034	4.503LysGly: 4.503 ± 0.063	1.128LysHis: 1.128 ± 0.023	4.199LysIle: 4.199 ± 0.064	4.669LysLys: 4.669 ± 0.074	5.013LysLeu: 5.013 ± 0.064	1.972LysMet: 1.972 ± 0.037	3.477LysAsn: 3.477 ± 0.054	2.186LysPro: 2.186 ± 0.04	2.418LysGln: 2.418 ± 0.039	3.212LysArg: 3.212 ± 0.05	3.379LysSer: 3.379 ± 0.047	3.242LysThr: 3.242 ± 0.053	4.271LysVal: 4.271 ± 0.058	0.727LysTrp: 0.727 ± 0.023	2.804LysTyr: 2.804 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	6.452LeuAla: 6.452 ± 0.08	1.307LeuCys: 1.307 ± 0.029	4.981LeuAsp: 4.981 ± 0.067	5.145LeuGlu: 5.145 ± 0.067	4.873LeuPhe: 4.873 ± 0.081	5.925LeuGly: 5.925 ± 0.085	1.585LeuHis: 1.585 ± 0.033	5.895LeuIle: 5.895 ± 0.086	6.082LeuLys: 6.082 ± 0.069	9.479LeuLeu: 9.479 ± 0.105	2.459LeuMet: 2.459 ± 0.044	4.637LeuAsn: 4.637 ± 0.06	4.311LeuPro: 4.311 ± 0.055	2.961LeuGln: 2.961 ± 0.047	4.93LeuArg: 4.93 ± 0.054	7.227LeuSer: 7.227 ± 0.075	5.078LeuThr: 5.078 ± 0.067	5.317LeuVal: 5.317 ± 0.07	0.986LeuTrp: 0.986 ± 0.025	3.808LeuTyr: 3.808 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.066MetAla: 2.066 ± 0.036	0.249MetCys: 0.249 ± 0.014	1.621MetAsp: 1.621 ± 0.033	1.91MetGlu: 1.91 ± 0.04	0.982MetPhe: 0.982 ± 0.028	1.849MetGly: 1.849 ± 0.038	0.379MetHis: 0.379 ± 0.015	1.768MetIle: 1.768 ± 0.039	2.226MetLys: 2.226 ± 0.036	2.448MetLeu: 2.448 ± 0.05	0.801MetMet: 0.801 ± 0.027	1.638MetAsn: 1.638 ± 0.032	1.189MetPro: 1.189 ± 0.03	0.917MetGln: 0.917 ± 0.026	1.6MetArg: 1.6 ± 0.034	1.582MetSer: 1.582 ± 0.032	1.361MetThr: 1.361 ± 0.029	1.618MetVal: 1.618 ± 0.029	0.232MetTrp: 0.232 ± 0.014	0.924MetTyr: 0.924 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.472AsnAla: 3.472 ± 0.053	0.469AsnCys: 0.469 ± 0.021	2.529AsnAsp: 2.529 ± 0.048	3.012AsnGlu: 3.012 ± 0.055	2.192AsnPhe: 2.192 ± 0.042	3.776AsnGly: 3.776 ± 0.062	0.946AsnHis: 0.946 ± 0.026	3.594AsnIle: 3.594 ± 0.062	3.072AsnLys: 3.072 ± 0.053	4.392AsnLeu: 4.392 ± 0.065	1.315AsnMet: 1.315 ± 0.029	2.525AsnAsn: 2.525 ± 0.055	2.541AsnPro: 2.541 ± 0.038	1.638AsnGln: 1.638 ± 0.036	2.429AsnArg: 2.429 ± 0.05	2.776AsnSer: 2.776 ± 0.046	2.802AsnThr: 2.802 ± 0.052	3.192AsnVal: 3.192 ± 0.053	0.66AsnTrp: 0.66 ± 0.024	2.355AsnTyr: 2.355 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	2.782ProAla: 2.782 ± 0.044	0.361ProCys: 0.361 ± 0.016	2.728ProAsp: 2.728 ± 0.046	3.56ProGlu: 3.56 ± 0.055	2.035ProPhe: 2.035 ± 0.042	2.575ProGly: 2.575 ± 0.05	0.695ProHis: 0.695 ± 0.023	2.566ProIle: 2.566 ± 0.039	2.074ProLys: 2.074 ± 0.036	3.439ProLeu: 3.439 ± 0.047	0.979ProMet: 0.979 ± 0.027	1.825ProAsn: 1.825 ± 0.037	0.91ProPro: 0.91 ± 0.027	1.278ProGln: 1.278 ± 0.03	1.374ProArg: 1.374 ± 0.039	2.523ProSer: 2.523 ± 0.043	2.063ProThr: 2.063 ± 0.037	3.085ProVal: 3.085 ± 0.05	0.458ProTrp: 0.458 ± 0.018	1.786ProTyr: 1.786 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	2.466GlnAla: 2.466 ± 0.044	0.264GlnCys: 0.264 ± 0.014	1.63GlnAsp: 1.63 ± 0.033	2.29GlnGlu: 2.29 ± 0.041	1.296GlnPhe: 1.296 ± 0.031	2.083GlnGly: 2.083 ± 0.04	0.522GlnHis: 0.522 ± 0.019	2.395GlnIle: 2.395 ± 0.04	2.267GlnLys: 2.267 ± 0.044	3.208GlnLeu: 3.208 ± 0.053	0.961GlnMet: 0.961 ± 0.027	1.579GlnAsn: 1.579 ± 0.03	1.273GlnPro: 1.273 ± 0.03	1.373GlnGln: 1.373 ± 0.039	1.562GlnArg: 1.562 ± 0.031	1.896GlnSer: 1.896 ± 0.037	1.92GlnThr: 1.92 ± 0.038	2.167GlnVal: 2.167 ± 0.036	0.401GlnTrp: 0.401 ± 0.017	1.42GlnTyr: 1.42 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.715ArgAla: 2.715 ± 0.05	0.47ArgCys: 0.47 ± 0.019	2.267ArgAsp: 2.267 ± 0.042	3.188ArgGlu: 3.188 ± 0.057	2.483ArgPhe: 2.483 ± 0.045	2.502ArgGly: 2.502 ± 0.045	0.927ArgHis: 0.927 ± 0.024	3.859ArgIle: 3.859 ± 0.05	3.53ArgLys: 3.53 ± 0.053	4.844ArgLeu: 4.844 ± 0.061	1.552ArgMet: 1.552 ± 0.031	2.484ArgAsn: 2.484 ± 0.045	1.751ArgPro: 1.751 ± 0.035	1.8ArgGln: 1.8 ± 0.035	2.311ArgArg: 2.311 ± 0.045	2.662ArgSer: 2.662 ± 0.045	2.514ArgThr: 2.514 ± 0.038	2.747ArgVal: 2.747 ± 0.041	0.66ArgTrp: 0.66 ± 0.023	2.382ArgTyr: 2.382 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	4.115SerAla: 4.115 ± 0.057	0.811SerCys: 0.811 ± 0.026	3.539SerAsp: 3.539 ± 0.05	3.568SerGlu: 3.568 ± 0.047	3.56SerPhe: 3.56 ± 0.051	4.764SerGly: 4.764 ± 0.069	1.139SerHis: 1.139 ± 0.03	4.47SerIle: 4.47 ± 0.062	3.438SerLys: 3.438 ± 0.048	6.472SerLeu: 6.472 ± 0.076	1.568SerMet: 1.568 ± 0.034	2.614SerAsn: 2.614 ± 0.046	2.591SerPro: 2.591 ± 0.04	1.823SerGln: 1.823 ± 0.039	2.813SerArg: 2.813 ± 0.046	4.124SerSer: 4.124 ± 0.07	3.305SerThr: 3.305 ± 0.055	4.482SerVal: 4.482 ± 0.057	0.797SerTrp: 0.797 ± 0.025	3.057SerTyr: 3.057 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	3.815ThrAla: 3.815 ± 0.066	0.562ThrCys: 0.562 ± 0.019	3.294ThrAsp: 3.294 ± 0.054	3.204ThrGlu: 3.204 ± 0.052	2.85ThrPhe: 2.85 ± 0.045	4.254ThrGly: 4.254 ± 0.063	1.051ThrHis: 1.051 ± 0.029	3.913ThrIle: 3.913 ± 0.06	2.698ThrLys: 2.698 ± 0.052	5.424ThrLeu: 5.424 ± 0.07	1.213ThrMet: 1.213 ± 0.03	2.498ThrAsn: 2.498 ± 0.05	2.779ThrPro: 2.779 ± 0.042	1.769ThrGln: 1.769 ± 0.036	2.257ThrArg: 2.257 ± 0.036	3.392ThrSer: 3.392 ± 0.047	3.08ThrThr: 3.08 ± 0.054	3.937ThrVal: 3.937 ± 0.06	0.636ThrTrp: 0.636 ± 0.024	2.434ThrTyr: 2.434 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	4.517ValAla: 4.517 ± 0.069	0.934ValCys: 0.934 ± 0.026	3.659ValAsp: 3.659 ± 0.057	4.046ValGlu: 4.046 ± 0.057	3.035ValPhe: 3.035 ± 0.054	4.18ValGly: 4.18 ± 0.062	1.033ValHis: 1.033 ± 0.029	4.48ValIle: 4.48 ± 0.068	4.129ValLys: 4.129 ± 0.058	5.982ValLeu: 5.982 ± 0.071	1.712ValMet: 1.712 ± 0.042	3.323ValAsn: 3.323 ± 0.057	2.648ValPro: 2.648 ± 0.046	1.826ValGln: 1.826 ± 0.036	3.107ValArg: 3.107 ± 0.047	4.72ValSer: 4.72 ± 0.069	3.827ValThr: 3.827 ± 0.06	4.472ValVal: 4.472 ± 0.066	0.748ValTrp: 0.748 ± 0.024	2.764ValTyr: 2.764 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.737TrpAla: 0.737 ± 0.022	0.154TrpCys: 0.154 ± 0.011	0.72TrpAsp: 0.72 ± 0.024	0.759TrpGlu: 0.759 ± 0.023	0.597TrpPhe: 0.597 ± 0.022	0.931TrpGly: 0.931 ± 0.025	0.264TrpHis: 0.264 ± 0.014	0.861TrpIle: 0.861 ± 0.025	0.897TrpLys: 0.897 ± 0.027	1.179TrpLeu: 1.179 ± 0.031	0.431TrpMet: 0.431 ± 0.021	0.739TrpAsn: 0.739 ± 0.026	0.297TrpPro: 0.297 ± 0.014	0.462TrpGln: 0.462 ± 0.019	0.59TrpArg: 0.59 ± 0.021	0.665TrpSer: 0.665 ± 0.023	0.641TrpThr: 0.641 ± 0.021	0.763TrpVal: 0.763 ± 0.025	0.188TrpTrp: 0.188 ± 0.012	0.537TrpTyr: 0.537 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.903TyrAla: 2.903 ± 0.045	0.527TyrCys: 0.527 ± 0.021	2.574TyrAsp: 2.574 ± 0.047	2.418TyrGlu: 2.418 ± 0.041	2.172TyrPhe: 2.172 ± 0.036	3.009TyrGly: 3.009 ± 0.059	0.897TyrHis: 0.897 ± 0.024	2.882TyrIle: 2.882 ± 0.045	2.777TyrLys: 2.777 ± 0.046	4.12TyrLeu: 4.12 ± 0.05	1.13TyrMet: 1.13 ± 0.026	2.422TyrAsn: 2.422 ± 0.051	2.05TyrPro: 2.05 ± 0.038	1.591TyrGln: 1.591 ± 0.034	2.226TyrArg: 2.226 ± 0.042	2.753TyrSer: 2.753 ± 0.056	2.808TyrThr: 2.808 ± 0.05	2.578TyrVal: 2.578 ± 0.044	0.602TyrTrp: 0.602 ± 0.022	2.075TyrTyr: 2.075 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3830 proteins (1437791 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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