Amino acid dipepetide frequency for Burkholderia phage ST79

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.998AlaAla: 16.998 ± 1.703
1.349AlaCys: 1.349 ± 0.452
8.634AlaAsp: 8.634 ± 0.878
6.385AlaGlu: 6.385 ± 0.718
3.238AlaPhe: 3.238 ± 0.473
8.094AlaGly: 8.094 ± 1.283
1.889AlaHis: 1.889 ± 0.429
5.216AlaIle: 5.216 ± 1.061
4.946AlaLys: 4.946 ± 0.673
10.792AlaLeu: 10.792 ± 0.919
4.047AlaMet: 4.047 ± 0.58
3.148AlaAsn: 3.148 ± 0.655
7.015AlaPro: 7.015 ± 0.916
4.227AlaGln: 4.227 ± 0.54
10.073AlaArg: 10.073 ± 1.133
8.634AlaSer: 8.634 ± 0.814
7.465AlaThr: 7.465 ± 0.483
8.454AlaVal: 8.454 ± 0.893
3.418AlaTrp: 3.418 ± 0.636
3.238AlaTyr: 3.238 ± 0.454
0.0AlaXaa: 0.0 ± 0.0
Cys
1.439CysAla: 1.439 ± 0.45
0.18CysCys: 0.18 ± 0.123
1.079CysAsp: 1.079 ± 0.322
0.36CysGlu: 0.36 ± 0.182
0.18CysPhe: 0.18 ± 0.13
0.989CysGly: 0.989 ± 0.305
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.54CysLys: 0.54 ± 0.249
0.63CysLeu: 0.63 ± 0.239
0.27CysMet: 0.27 ± 0.145
0.0CysAsn: 0.0 ± 0.0
0.899CysPro: 0.899 ± 0.319
0.27CysGln: 0.27 ± 0.215
0.54CysArg: 0.54 ± 0.19
0.09CysSer: 0.09 ± 0.083
0.63CysThr: 0.63 ± 0.255
0.719CysVal: 0.719 ± 0.279
0.18CysTrp: 0.18 ± 0.142
0.09CysTyr: 0.09 ± 0.099
0.0CysXaa: 0.0 ± 0.0
Asp
9.983AspAla: 9.983 ± 0.965
0.719AspCys: 0.719 ± 0.246
5.306AspAsp: 5.306 ± 0.792
3.418AspGlu: 3.418 ± 0.723
2.788AspPhe: 2.788 ± 0.449
7.735AspGly: 7.735 ± 1.117
0.899AspHis: 0.899 ± 0.324
2.338AspIle: 2.338 ± 0.408
1.169AspLys: 1.169 ± 0.324
4.946AspLeu: 4.946 ± 0.797
1.799AspMet: 1.799 ± 0.388
1.349AspAsn: 1.349 ± 0.342
4.047AspPro: 4.047 ± 0.558
2.698AspGln: 2.698 ± 0.487
4.047AspArg: 4.047 ± 0.751
2.968AspSer: 2.968 ± 0.449
3.058AspThr: 3.058 ± 0.644
3.687AspVal: 3.687 ± 0.633
0.989AspTrp: 0.989 ± 0.283
1.889AspTyr: 1.889 ± 0.373
0.0AspXaa: 0.0 ± 0.0
Glu
4.857GluAla: 4.857 ± 0.773
0.36GluCys: 0.36 ± 0.164
1.529GluAsp: 1.529 ± 0.347
1.529GluGlu: 1.529 ± 0.279
2.069GluPhe: 2.069 ± 0.452
4.227GluGly: 4.227 ± 0.578
1.079GluHis: 1.079 ± 0.327
3.418GluIle: 3.418 ± 0.49
1.619GluLys: 1.619 ± 0.454
4.497GluLeu: 4.497 ± 0.545
2.158GluMet: 2.158 ± 0.489
1.889GluAsn: 1.889 ± 0.364
2.338GluPro: 2.338 ± 0.454
2.338GluGln: 2.338 ± 0.511
4.407GluArg: 4.407 ± 0.795
3.148GluSer: 3.148 ± 0.646
2.698GluThr: 2.698 ± 0.455
3.328GluVal: 3.328 ± 0.552
0.989GluTrp: 0.989 ± 0.357
0.719GluTyr: 0.719 ± 0.245
0.0GluXaa: 0.0 ± 0.0
Phe
6.026PheAla: 6.026 ± 0.699
0.18PheCys: 0.18 ± 0.139
2.338PheAsp: 2.338 ± 0.374
2.428PheGlu: 2.428 ± 0.47
1.169PhePhe: 1.169 ± 0.245
3.148PheGly: 3.148 ± 0.503
0.899PheHis: 0.899 ± 0.342
1.439PheIle: 1.439 ± 0.372
0.989PheLys: 0.989 ± 0.266
2.069PheLeu: 2.069 ± 0.386
0.899PheMet: 0.899 ± 0.286
0.899PheAsn: 0.899 ± 0.207
1.079PhePro: 1.079 ± 0.308
0.719PheGln: 0.719 ± 0.234
2.788PheArg: 2.788 ± 0.489
1.709PheSer: 1.709 ± 0.438
1.979PheThr: 1.979 ± 0.438
1.799PheVal: 1.799 ± 0.375
0.719PheTrp: 0.719 ± 0.293
0.719PheTyr: 0.719 ± 0.259
0.0PheXaa: 0.0 ± 0.0
Gly
10.882GlyAla: 10.882 ± 1.21
0.45GlyCys: 0.45 ± 0.197
5.306GlyAsp: 5.306 ± 0.586
4.407GlyGlu: 4.407 ± 0.701
3.508GlyPhe: 3.508 ± 0.452
8.904GlyGly: 8.904 ± 1.599
1.259GlyHis: 1.259 ± 0.376
3.867GlyIle: 3.867 ± 0.485
3.418GlyLys: 3.418 ± 0.518
4.857GlyLeu: 4.857 ± 0.709
1.979GlyMet: 1.979 ± 0.435
3.238GlyAsn: 3.238 ± 1.592
2.428GlyPro: 2.428 ± 0.405
2.428GlyGln: 2.428 ± 0.366
5.756GlyArg: 5.756 ± 0.631
4.407GlySer: 4.407 ± 0.783
5.756GlyThr: 5.756 ± 1.038
7.465GlyVal: 7.465 ± 0.644
1.889GlyTrp: 1.889 ± 0.407
2.518GlyTyr: 2.518 ± 0.702
0.0GlyXaa: 0.0 ± 0.0
His
2.158HisAla: 2.158 ± 0.443
0.36HisCys: 0.36 ± 0.213
0.54HisAsp: 0.54 ± 0.203
0.63HisGlu: 0.63 ± 0.252
1.169HisPhe: 1.169 ± 0.286
2.158HisGly: 2.158 ± 0.385
0.54HisHis: 0.54 ± 0.209
0.989HisIle: 0.989 ± 0.331
0.45HisLys: 0.45 ± 0.163
0.989HisLeu: 0.989 ± 0.305
0.18HisMet: 0.18 ± 0.127
0.09HisAsn: 0.09 ± 0.074
0.54HisPro: 0.54 ± 0.214
0.809HisGln: 0.809 ± 0.33
1.709HisArg: 1.709 ± 0.319
1.079HisSer: 1.079 ± 0.267
0.899HisThr: 0.899 ± 0.268
1.349HisVal: 1.349 ± 0.291
0.54HisTrp: 0.54 ± 0.27
0.63HisTyr: 0.63 ± 0.319
0.0HisXaa: 0.0 ± 0.0
Ile
5.936IleAla: 5.936 ± 0.709
0.09IleCys: 0.09 ± 0.095
4.587IleAsp: 4.587 ± 0.591
2.878IleGlu: 2.878 ± 0.582
0.809IlePhe: 0.809 ± 0.28
5.756IleGly: 5.756 ± 0.658
1.259IleHis: 1.259 ± 0.382
1.079IleIle: 1.079 ± 0.336
1.979IleLys: 1.979 ± 0.6
2.968IleLeu: 2.968 ± 0.348
0.989IleMet: 0.989 ± 0.279
1.529IleAsn: 1.529 ± 0.361
1.169IlePro: 1.169 ± 0.359
1.259IleGln: 1.259 ± 0.275
3.328IleArg: 3.328 ± 0.575
1.799IleSer: 1.799 ± 0.364
4.587IleThr: 4.587 ± 0.546
2.878IleVal: 2.878 ± 0.465
0.63IleTrp: 0.63 ± 0.182
0.899IleTyr: 0.899 ± 0.217
0.0IleXaa: 0.0 ± 0.0
Lys
4.587LysAla: 4.587 ± 0.771
0.18LysCys: 0.18 ± 0.137
1.439LysAsp: 1.439 ± 0.364
2.069LysGlu: 2.069 ± 0.598
1.799LysPhe: 1.799 ± 0.349
2.608LysGly: 2.608 ± 0.66
0.54LysHis: 0.54 ± 0.219
1.889LysIle: 1.889 ± 0.397
1.979LysLys: 1.979 ± 0.475
3.597LysLeu: 3.597 ± 0.773
0.899LysMet: 0.899 ± 0.235
1.529LysAsn: 1.529 ± 0.376
3.058LysPro: 3.058 ± 0.584
1.349LysGln: 1.349 ± 0.285
3.328LysArg: 3.328 ± 0.66
1.709LysSer: 1.709 ± 0.417
1.979LysThr: 1.979 ± 0.517
1.799LysVal: 1.799 ± 0.411
0.18LysTrp: 0.18 ± 0.144
0.719LysTyr: 0.719 ± 0.311
0.0LysXaa: 0.0 ± 0.0
Leu
9.353LeuAla: 9.353 ± 0.902
0.899LeuCys: 0.899 ± 0.325
5.126LeuAsp: 5.126 ± 0.639
3.597LeuGlu: 3.597 ± 0.61
2.608LeuPhe: 2.608 ± 0.521
5.216LeuGly: 5.216 ± 0.724
1.439LeuHis: 1.439 ± 0.271
3.508LeuIle: 3.508 ± 0.546
2.158LeuLys: 2.158 ± 0.446
5.576LeuLeu: 5.576 ± 0.727
1.709LeuMet: 1.709 ± 0.403
3.328LeuAsn: 3.328 ± 0.587
4.047LeuPro: 4.047 ± 0.592
2.698LeuGln: 2.698 ± 0.568
6.385LeuArg: 6.385 ± 0.757
5.576LeuSer: 5.576 ± 0.535
5.486LeuThr: 5.486 ± 0.716
5.666LeuVal: 5.666 ± 0.671
0.899LeuTrp: 0.899 ± 0.316
1.709LeuTyr: 1.709 ± 0.398
0.0LeuXaa: 0.0 ± 0.0
Met
1.889MetAla: 1.889 ± 0.427
0.09MetCys: 0.09 ± 0.083
0.989MetAsp: 0.989 ± 0.326
0.899MetGlu: 0.899 ± 0.251
0.63MetPhe: 0.63 ± 0.183
1.079MetGly: 1.079 ± 0.27
0.54MetHis: 0.54 ± 0.195
0.899MetIle: 0.899 ± 0.281
1.349MetLys: 1.349 ± 0.337
2.338MetLeu: 2.338 ± 0.424
0.27MetMet: 0.27 ± 0.209
1.799MetAsn: 1.799 ± 0.478
1.619MetPro: 1.619 ± 0.346
0.809MetGln: 0.809 ± 0.274
2.428MetArg: 2.428 ± 0.422
1.979MetSer: 1.979 ± 0.462
2.608MetThr: 2.608 ± 0.555
1.619MetVal: 1.619 ± 0.333
0.09MetTrp: 0.09 ± 0.103
0.36MetTyr: 0.36 ± 0.172
0.0MetXaa: 0.0 ± 0.0
Asn
5.216AsnAla: 5.216 ± 0.896
0.36AsnCys: 0.36 ± 0.167
2.248AsnAsp: 2.248 ± 0.538
2.878AsnGlu: 2.878 ± 0.464
1.169AsnPhe: 1.169 ± 0.465
3.777AsnGly: 3.777 ± 1.114
0.18AsnHis: 0.18 ± 0.117
1.259AsnIle: 1.259 ± 0.254
0.719AsnLys: 0.719 ± 0.214
2.248AsnLeu: 2.248 ± 0.473
0.809AsnMet: 0.809 ± 0.355
0.899AsnAsn: 0.899 ± 0.46
1.799AsnPro: 1.799 ± 0.457
1.079AsnGln: 1.079 ± 0.321
2.608AsnArg: 2.608 ± 0.763
1.529AsnSer: 1.529 ± 0.486
1.169AsnThr: 1.169 ± 0.323
2.518AsnVal: 2.518 ± 0.472
0.63AsnTrp: 0.63 ± 0.234
0.899AsnTyr: 0.899 ± 0.279
0.0AsnXaa: 0.0 ± 0.0
Pro
6.385ProAla: 6.385 ± 0.856
0.27ProCys: 0.27 ± 0.178
4.227ProAsp: 4.227 ± 0.767
2.248ProGlu: 2.248 ± 0.544
1.259ProPhe: 1.259 ± 0.248
2.968ProGly: 2.968 ± 0.536
0.989ProHis: 0.989 ± 0.328
2.788ProIle: 2.788 ± 0.486
1.619ProLys: 1.619 ± 0.444
3.328ProLeu: 3.328 ± 0.592
0.719ProMet: 0.719 ± 0.226
1.709ProAsn: 1.709 ± 0.527
2.608ProPro: 2.608 ± 0.638
1.169ProGln: 1.169 ± 0.38
2.788ProArg: 2.788 ± 0.655
3.148ProSer: 3.148 ± 0.441
2.608ProThr: 2.608 ± 0.522
3.508ProVal: 3.508 ± 0.642
0.63ProTrp: 0.63 ± 0.2
1.439ProTyr: 1.439 ± 0.386
0.0ProXaa: 0.0 ± 0.0
Gln
3.957GlnAla: 3.957 ± 0.679
0.36GlnCys: 0.36 ± 0.19
1.259GlnAsp: 1.259 ± 0.338
1.169GlnGlu: 1.169 ± 0.326
1.259GlnPhe: 1.259 ± 0.313
2.428GlnGly: 2.428 ± 0.528
0.54GlnHis: 0.54 ± 0.193
1.799GlnIle: 1.799 ± 0.434
1.799GlnLys: 1.799 ± 0.397
1.889GlnLeu: 1.889 ± 0.357
0.809GlnMet: 0.809 ± 0.249
1.169GlnAsn: 1.169 ± 0.302
0.989GlnPro: 0.989 ± 0.294
1.799GlnGln: 1.799 ± 0.461
2.788GlnArg: 2.788 ± 0.657
1.799GlnSer: 1.799 ± 0.332
2.518GlnThr: 2.518 ± 0.531
2.968GlnVal: 2.968 ± 0.531
0.899GlnTrp: 0.899 ± 0.222
0.45GlnTyr: 0.45 ± 0.18
0.0GlnXaa: 0.0 ± 0.0
Arg
12.231ArgAla: 12.231 ± 1.316
0.809ArgCys: 0.809 ± 0.321
6.296ArgAsp: 6.296 ± 0.844
4.047ArgGlu: 4.047 ± 0.596
1.619ArgPhe: 1.619 ± 0.449
5.846ArgGly: 5.846 ± 0.743
1.709ArgHis: 1.709 ± 0.478
3.687ArgIle: 3.687 ± 0.764
2.878ArgLys: 2.878 ± 0.449
5.756ArgLeu: 5.756 ± 0.662
1.439ArgMet: 1.439 ± 0.346
2.788ArgAsn: 2.788 ± 0.488
2.608ArgPro: 2.608 ± 0.428
2.878ArgGln: 2.878 ± 0.664
7.555ArgArg: 7.555 ± 1.231
2.878ArgSer: 2.878 ± 0.63
4.317ArgThr: 4.317 ± 0.572
7.465ArgVal: 7.465 ± 0.548
1.079ArgTrp: 1.079 ± 0.277
2.518ArgTyr: 2.518 ± 0.37
0.0ArgXaa: 0.0 ± 0.0
Ser
6.745SerAla: 6.745 ± 0.624
0.27SerCys: 0.27 ± 0.178
3.148SerAsp: 3.148 ± 0.462
2.338SerGlu: 2.338 ± 0.437
1.439SerPhe: 1.439 ± 0.411
6.206SerGly: 6.206 ± 0.81
0.719SerHis: 0.719 ± 0.287
2.968SerIle: 2.968 ± 0.452
2.698SerLys: 2.698 ± 0.56
3.777SerLeu: 3.777 ± 0.503
0.989SerMet: 0.989 ± 0.287
2.428SerAsn: 2.428 ± 0.597
2.608SerPro: 2.608 ± 0.38
0.989SerGln: 0.989 ± 0.259
4.407SerArg: 4.407 ± 0.721
2.158SerSer: 2.158 ± 0.372
2.968SerThr: 2.968 ± 0.645
4.497SerVal: 4.497 ± 0.572
1.259SerTrp: 1.259 ± 0.348
1.799SerTyr: 1.799 ± 0.447
0.0SerXaa: 0.0 ± 0.0
Thr
5.846ThrAla: 5.846 ± 0.634
0.54ThrCys: 0.54 ± 0.27
3.328ThrAsp: 3.328 ± 0.618
1.709ThrGlu: 1.709 ± 0.479
2.608ThrPhe: 2.608 ± 0.449
5.036ThrGly: 5.036 ± 0.797
1.169ThrHis: 1.169 ± 0.358
3.418ThrIle: 3.418 ± 0.566
2.158ThrLys: 2.158 ± 0.366
5.666ThrLeu: 5.666 ± 0.791
1.619ThrMet: 1.619 ± 0.486
2.248ThrAsn: 2.248 ± 0.471
3.328ThrPro: 3.328 ± 0.545
2.069ThrGln: 2.069 ± 0.388
5.036ThrArg: 5.036 ± 0.563
3.328ThrSer: 3.328 ± 0.667
3.508ThrThr: 3.508 ± 0.472
6.296ThrVal: 6.296 ± 0.577
1.259ThrTrp: 1.259 ± 0.35
0.899ThrTyr: 0.899 ± 0.324
0.0ThrXaa: 0.0 ± 0.0
Val
8.274ValAla: 8.274 ± 1.003
0.899ValCys: 0.899 ± 0.211
5.666ValAsp: 5.666 ± 0.774
4.677ValGlu: 4.677 ± 0.948
2.069ValPhe: 2.069 ± 0.32
5.576ValGly: 5.576 ± 0.93
1.079ValHis: 1.079 ± 0.355
4.227ValIle: 4.227 ± 0.637
3.508ValLys: 3.508 ± 0.622
6.745ValLeu: 6.745 ± 0.713
1.799ValMet: 1.799 ± 0.343
2.428ValAsn: 2.428 ± 0.569
2.878ValPro: 2.878 ± 0.615
2.248ValGln: 2.248 ± 0.349
6.655ValArg: 6.655 ± 0.81
4.317ValSer: 4.317 ± 0.708
4.047ValThr: 4.047 ± 0.826
6.116ValVal: 6.116 ± 0.648
0.989ValTrp: 0.989 ± 0.3
1.799ValTyr: 1.799 ± 0.381
0.0ValXaa: 0.0 ± 0.0
Trp
2.158TrpAla: 2.158 ± 0.525
0.36TrpCys: 0.36 ± 0.175
0.989TrpAsp: 0.989 ± 0.309
0.899TrpGlu: 0.899 ± 0.292
0.809TrpPhe: 0.809 ± 0.302
0.899TrpGly: 0.899 ± 0.31
0.719TrpHis: 0.719 ± 0.25
0.63TrpIle: 0.63 ± 0.256
0.899TrpLys: 0.899 ± 0.372
1.619TrpLeu: 1.619 ± 0.33
0.27TrpMet: 0.27 ± 0.186
0.899TrpAsn: 0.899 ± 0.293
0.63TrpPro: 0.63 ± 0.283
0.45TrpGln: 0.45 ± 0.199
1.439TrpArg: 1.439 ± 0.44
1.079TrpSer: 1.079 ± 0.303
1.169TrpThr: 1.169 ± 0.339
1.349TrpVal: 1.349 ± 0.311
0.18TrpTrp: 0.18 ± 0.114
0.54TrpTyr: 0.54 ± 0.185
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.338TyrAla: 2.338 ± 0.391
0.36TyrCys: 0.36 ± 0.139
1.799TyrAsp: 1.799 ± 0.301
0.719TyrGlu: 0.719 ± 0.274
1.799TyrPhe: 1.799 ± 0.388
2.069TyrGly: 2.069 ± 0.489
0.36TyrHis: 0.36 ± 0.17
0.989TyrIle: 0.989 ± 0.302
0.36TyrLys: 0.36 ± 0.225
2.698TyrLeu: 2.698 ± 0.5
0.54TyrMet: 0.54 ± 0.211
0.63TyrAsn: 0.63 ± 0.236
0.719TyrPro: 0.719 ± 0.217
0.36TyrGln: 0.36 ± 0.169
2.338TyrArg: 2.338 ± 0.392
1.079TyrSer: 1.079 ± 0.358
1.619TyrThr: 1.619 ± 0.433
2.518TyrVal: 2.518 ± 0.588
0.54TyrTrp: 0.54 ± 0.196
0.45TyrTyr: 0.45 ± 0.193
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 49 proteins (11120 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski