Amino acid dipepetide frequency for Absicoccus porci

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.844AlaAla: 4.844 ± 0.115	1.339AlaCys: 1.339 ± 0.046	3.878AlaAsp: 3.878 ± 0.077	3.334AlaGlu: 3.334 ± 0.089	3.094AlaPhe: 3.094 ± 0.068	4.542AlaGly: 4.542 ± 0.107	1.611AlaHis: 1.611 ± 0.049	6.094AlaIle: 6.094 ± 0.113	5.622AlaLys: 5.622 ± 0.108	6.827AlaLeu: 6.827 ± 0.106	2.443AlaMet: 2.443 ± 0.065	3.296AlaAsn: 3.296 ± 0.073	1.713AlaPro: 1.713 ± 0.053	3.121AlaGln: 3.121 ± 0.078	2.571AlaArg: 2.571 ± 0.076	4.044AlaSer: 4.044 ± 0.096	3.727AlaThr: 3.727 ± 0.088	4.225AlaVal: 4.225 ± 0.091	0.667AlaTrp: 0.667 ± 0.035	3.112AlaTyr: 3.112 ± 0.07	0.002AlaXaa: 0.002 ± 0.001
Cys	1.06CysAla: 1.06 ± 0.042	0.248CysCys: 0.248 ± 0.017	0.979CysAsp: 0.979 ± 0.036	0.884CysGlu: 0.884 ± 0.035	0.709CysPhe: 0.709 ± 0.034	1.243CysGly: 1.243 ± 0.051	0.434CysHis: 0.434 ± 0.028	1.227CysIle: 1.227 ± 0.051	0.835CysLys: 0.835 ± 0.035	1.217CysLeu: 1.217 ± 0.042	0.496CysMet: 0.496 ± 0.031	0.513CysAsn: 0.513 ± 0.03	0.659CysPro: 0.659 ± 0.04	0.604CysGln: 0.604 ± 0.029	0.529CysArg: 0.529 ± 0.03	0.858CysSer: 0.858 ± 0.034	0.857CysThr: 0.857 ± 0.043	0.998CysVal: 0.998 ± 0.04	0.103CysTrp: 0.103 ± 0.013	0.418CysTyr: 0.418 ± 0.027	0.0CysXaa: 0.0 ± 0.0
Asp	4.66AspAla: 4.66 ± 0.095	0.87AspCys: 0.87 ± 0.038	3.537AspAsp: 3.537 ± 0.092	4.439AspGlu: 4.439 ± 0.091	2.841AspPhe: 2.841 ± 0.067	3.984AspGly: 3.984 ± 0.094	1.637AspHis: 1.637 ± 0.055	5.091AspIle: 5.091 ± 0.102	3.365AspLys: 3.365 ± 0.077	5.515AspLeu: 5.515 ± 0.098	1.845AspMet: 1.845 ± 0.046	2.067AspAsn: 2.067 ± 0.063	2.407AspPro: 2.407 ± 0.057	2.597AspGln: 2.597 ± 0.067	2.424AspArg: 2.424 ± 0.064	3.152AspSer: 3.152 ± 0.074	3.696AspThr: 3.696 ± 0.084	4.594AspVal: 4.594 ± 0.086	0.693AspTrp: 0.693 ± 0.033	2.643AspTyr: 2.643 ± 0.061	0.002AspXaa: 0.002 ± 0.002
Glu	4.542GluAla: 4.542 ± 0.093	0.667GluCys: 0.667 ± 0.033	4.023GluAsp: 4.023 ± 0.101	4.781GluGlu: 4.781 ± 0.118	1.975GluPhe: 1.975 ± 0.061	3.212GluGly: 3.212 ± 0.079	1.413GluHis: 1.413 ± 0.05	4.965GluIle: 4.965 ± 0.111	5.846GluLys: 5.846 ± 0.102	5.35GluLeu: 5.35 ± 0.116	2.38GluMet: 2.38 ± 0.071	3.6GluAsn: 3.6 ± 0.065	1.859GluPro: 1.859 ± 0.056	2.904GluGln: 2.904 ± 0.079	2.394GluArg: 2.394 ± 0.062	3.079GluSer: 3.079 ± 0.07	3.46GluThr: 3.46 ± 0.074	3.944GluVal: 3.944 ± 0.086	0.616GluTrp: 0.616 ± 0.031	2.521GluTyr: 2.521 ± 0.069	0.0GluXaa: 0.0 ± 0.0
Phe	2.806PheAla: 2.806 ± 0.084	0.694PheCys: 0.694 ± 0.031	3.097PheAsp: 3.097 ± 0.075	2.584PheGlu: 2.584 ± 0.075	1.82PhePhe: 1.82 ± 0.062	3.026PheGly: 3.026 ± 0.079	1.194PheHis: 1.194 ± 0.047	2.936PheIle: 2.936 ± 0.079	2.188PheLys: 2.188 ± 0.064	3.397PheLeu: 3.397 ± 0.082	1.249PheMet: 1.249 ± 0.045	1.601PheAsn: 1.601 ± 0.048	1.368PhePro: 1.368 ± 0.041	1.52PheGln: 1.52 ± 0.051	1.385PheArg: 1.385 ± 0.051	2.561PheSer: 2.561 ± 0.063	2.343PheThr: 2.343 ± 0.066	3.075PheVal: 3.075 ± 0.091	0.391PheTrp: 0.391 ± 0.023	1.689PheTyr: 1.689 ± 0.049	0.0PheXaa: 0.0 ± 0.0
Gly	4.375GlyAla: 4.375 ± 0.102	1.128GlyCys: 1.128 ± 0.04	3.171GlyAsp: 3.171 ± 0.076	2.904GlyGlu: 2.904 ± 0.07	3.088GlyPhe: 3.088 ± 0.075	4.018GlyGly: 4.018 ± 0.105	1.627GlyHis: 1.627 ± 0.047	5.552GlyIle: 5.552 ± 0.107	4.72GlyLys: 4.72 ± 0.099	5.63GlyLeu: 5.63 ± 0.103	2.178GlyMet: 2.178 ± 0.055	2.761GlyAsn: 2.761 ± 0.068	1.535GlyPro: 1.535 ± 0.041	2.504GlyGln: 2.504 ± 0.065	2.332GlyArg: 2.332 ± 0.067	3.718GlySer: 3.718 ± 0.084	3.978GlyThr: 3.978 ± 0.097	4.257GlyVal: 4.257 ± 0.091	0.775GlyTrp: 0.775 ± 0.048	3.163GlyTyr: 3.163 ± 0.073	0.0GlyXaa: 0.0 ± 0.0
His	1.683HisAla: 1.683 ± 0.056	0.474HisCys: 0.474 ± 0.026	1.434HisAsp: 1.434 ± 0.051	1.316HisGlu: 1.316 ± 0.048	1.157HisPhe: 1.157 ± 0.043	1.673HisGly: 1.673 ± 0.051	0.729HisHis: 0.729 ± 0.04	1.937HisIle: 1.937 ± 0.054	1.344HisLys: 1.344 ± 0.052	2.228HisLeu: 2.228 ± 0.055	0.742HisMet: 0.742 ± 0.036	0.806HisAsn: 0.806 ± 0.032	1.246HisPro: 1.246 ± 0.042	0.991HisGln: 0.991 ± 0.04	1.088HisArg: 1.088 ± 0.045	1.269HisSer: 1.269 ± 0.041	1.453HisThr: 1.453 ± 0.052	1.805HisVal: 1.805 ± 0.059	0.29HisTrp: 0.29 ± 0.022	0.975HisTyr: 0.975 ± 0.041	0.0HisXaa: 0.0 ± 0.0
Ile	5.581IleAla: 5.581 ± 0.106	1.313IleCys: 1.313 ± 0.052	5.268IleAsp: 5.268 ± 0.106	5.261IleGlu: 5.261 ± 0.088	3.0IlePhe: 3.0 ± 0.078	5.163IleGly: 5.163 ± 0.108	2.24IleHis: 2.24 ± 0.064	5.322IleIle: 5.322 ± 0.119	4.418IleLys: 4.418 ± 0.077	7.086IleLeu: 7.086 ± 0.159	1.857IleMet: 1.857 ± 0.048	3.244IleAsn: 3.244 ± 0.084	3.198IlePro: 3.198 ± 0.073	3.808IleGln: 3.808 ± 0.096	3.304IleArg: 3.304 ± 0.069	4.635IleSer: 4.635 ± 0.083	4.246IleThr: 4.246 ± 0.098	5.54IleVal: 5.54 ± 0.104	0.637IleTrp: 0.637 ± 0.037	3.046IleTyr: 3.046 ± 0.079	0.002IleXaa: 0.002 ± 0.002
Lys	5.296LysAla: 5.296 ± 0.104	0.575LysCys: 0.575 ± 0.036	4.965LysAsp: 4.965 ± 0.088	6.51LysGlu: 6.51 ± 0.107	1.66LysPhe: 1.66 ± 0.053	4.064LysGly: 4.064 ± 0.08	1.474LysHis: 1.474 ± 0.049	4.743LysIle: 4.743 ± 0.083	6.781LysLys: 6.781 ± 0.121	4.609LysLeu: 4.609 ± 0.098	2.276LysMet: 2.276 ± 0.069	3.635LysAsn: 3.635 ± 0.07	2.28LysPro: 2.28 ± 0.058	3.448LysGln: 3.448 ± 0.075	3.049LysArg: 3.049 ± 0.074	3.387LysSer: 3.387 ± 0.087	4.165LysThr: 4.165 ± 0.08	4.622LysVal: 4.622 ± 0.086	0.625LysTrp: 0.625 ± 0.036	2.892LysTyr: 2.892 ± 0.074	0.003LysXaa: 0.003 ± 0.002
Leu	6.41LeuAla: 6.41 ± 0.112	1.401LeuCys: 1.401 ± 0.045	5.708LeuAsp: 5.708 ± 0.099	5.658LeuGlu: 5.658 ± 0.114	3.808LeuPhe: 3.808 ± 0.098	5.498LeuGly: 5.498 ± 0.113	2.133LeuHis: 2.133 ± 0.068	6.277LeuIle: 6.277 ± 0.123	5.88LeuLys: 5.88 ± 0.098	7.579LeuLeu: 7.579 ± 0.145	2.743LeuMet: 2.743 ± 0.069	3.65LeuAsn: 3.65 ± 0.07	3.247LeuPro: 3.247 ± 0.076	3.21LeuGln: 3.21 ± 0.075	3.282LeuArg: 3.282 ± 0.088	6.03LeuSer: 6.03 ± 0.1	4.447LeuThr: 4.447 ± 0.092	5.345LeuVal: 5.345 ± 0.093	0.673LeuTrp: 0.673 ± 0.034	3.319LeuTyr: 3.319 ± 0.073	0.003LeuXaa: 0.003 ± 0.002
Met	2.597MetAla: 2.597 ± 0.072	0.359MetCys: 0.359 ± 0.023	2.314MetAsp: 2.314 ± 0.063	2.145MetGlu: 2.145 ± 0.065	0.967MetPhe: 0.967 ± 0.04	1.952MetGly: 1.952 ± 0.053	0.791MetHis: 0.791 ± 0.04	2.518MetIle: 2.518 ± 0.066	2.743MetLys: 2.743 ± 0.065	2.3MetLeu: 2.3 ± 0.063	1.082MetMet: 1.082 ± 0.043	1.71MetAsn: 1.71 ± 0.05	1.169MetPro: 1.169 ± 0.04	1.195MetGln: 1.195 ± 0.038	1.128MetArg: 1.128 ± 0.037	1.799MetSer: 1.799 ± 0.052	1.719MetThr: 1.719 ± 0.061	1.932MetVal: 1.932 ± 0.058	0.176MetTrp: 0.176 ± 0.018	1.06MetTyr: 1.06 ± 0.042	0.005MetXaa: 0.005 ± 0.003
Asn	3.285AsnAla: 3.285 ± 0.086	0.562AsnCys: 0.562 ± 0.03	2.826AsnAsp: 2.826 ± 0.07	3.091AsnGlu: 3.091 ± 0.071	1.517AsnPhe: 1.517 ± 0.047	3.27AsnGly: 3.27 ± 0.079	1.246AsnHis: 1.246 ± 0.047	3.278AsnIle: 3.278 ± 0.072	2.895AsnLys: 2.895 ± 0.066	3.482AsnLeu: 3.482 ± 0.084	1.309AsnMet: 1.309 ± 0.041	1.909AsnAsn: 1.909 ± 0.07	2.007AsnPro: 2.007 ± 0.054	2.228AsnGln: 2.228 ± 0.057	1.988AsnArg: 1.988 ± 0.057	2.199AsnSer: 2.199 ± 0.061	2.596AsnThr: 2.596 ± 0.067	3.134AsnVal: 3.134 ± 0.071	0.474AsnTrp: 0.474 ± 0.03	1.813AsnTyr: 1.813 ± 0.053	0.002AsnXaa: 0.002 ± 0.002
Pro	2.027ProAla: 2.027 ± 0.064	0.472ProCys: 0.472 ± 0.029	2.133ProAsp: 2.133 ± 0.058	2.558ProGlu: 2.558 ± 0.065	1.586ProPhe: 1.586 ± 0.052	2.047ProGly: 2.047 ± 0.06	0.814ProHis: 0.814 ± 0.033	2.679ProIle: 2.679 ± 0.063	2.34ProLys: 2.34 ± 0.062	2.916ProLeu: 2.916 ± 0.082	1.068ProMet: 1.068 ± 0.04	1.776ProAsn: 1.776 ± 0.049	0.63ProPro: 0.63 ± 0.033	1.226ProGln: 1.226 ± 0.043	1.03ProArg: 1.03 ± 0.044	2.115ProSer: 2.115 ± 0.059	1.995ProThr: 1.995 ± 0.055	2.671ProVal: 2.671 ± 0.07	0.302ProTrp: 0.302 ± 0.024	1.652ProTyr: 1.652 ± 0.053	0.002ProXaa: 0.002 ± 0.001
Gln	3.575GlnAla: 3.575 ± 0.078	0.506GlnCys: 0.506 ± 0.031	2.368GlnAsp: 2.368 ± 0.065	2.792GlnGlu: 2.792 ± 0.076	1.479GlnPhe: 1.479 ± 0.04	2.32GlnGly: 2.32 ± 0.064	0.734GlnHis: 0.734 ± 0.036	3.327GlnIle: 3.327 ± 0.074	3.459GlnLys: 3.459 ± 0.083	3.638GlnLeu: 3.638 ± 0.086	1.537GlnMet: 1.537 ± 0.046	1.915GlnAsn: 1.915 ± 0.056	1.37GlnPro: 1.37 ± 0.047	1.805GlnGln: 1.805 ± 0.064	1.764GlnArg: 1.764 ± 0.06	2.421GlnSer: 2.421 ± 0.057	2.64GlnThr: 2.64 ± 0.061	2.619GlnVal: 2.619 ± 0.07	0.526GlnTrp: 0.526 ± 0.027	1.649GlnTyr: 1.649 ± 0.057	0.002GlnXaa: 0.002 ± 0.001
Arg	2.25ArgAla: 2.25 ± 0.066	0.582ArgCys: 0.582 ± 0.032	1.945ArgAsp: 1.945 ± 0.051	2.191ArgGlu: 2.191 ± 0.062	1.886ArgPhe: 1.886 ± 0.056	1.928ArgGly: 1.928 ± 0.055	0.863ArgHis: 0.863 ± 0.033	3.33ArgIle: 3.33 ± 0.085	3.353ArgLys: 3.353 ± 0.081	3.567ArgLeu: 3.567 ± 0.08	1.503ArgMet: 1.503 ± 0.049	1.977ArgAsn: 1.977 ± 0.058	1.267ArgPro: 1.267 ± 0.045	1.617ArgGln: 1.617 ± 0.051	1.706ArgArg: 1.706 ± 0.056	2.151ArgSer: 2.151 ± 0.049	1.984ArgThr: 1.984 ± 0.051	2.41ArgVal: 2.41 ± 0.059	0.417ArgTrp: 0.417 ± 0.027	1.843ArgTyr: 1.843 ± 0.057	0.002ArgXaa: 0.002 ± 0.002
Ser	3.515SerAla: 3.515 ± 0.087	0.815SerCys: 0.815 ± 0.038	3.264SerAsp: 3.264 ± 0.078	3.158SerGlu: 3.158 ± 0.077	2.669SerPhe: 2.669 ± 0.061	3.957SerGly: 3.957 ± 0.088	1.437SerHis: 1.437 ± 0.044	4.922SerIle: 4.922 ± 0.097	4.018SerLys: 4.018 ± 0.099	5.34SerLeu: 5.34 ± 0.097	1.923SerMet: 1.923 ± 0.053	2.62SerAsn: 2.62 ± 0.067	1.707SerPro: 1.707 ± 0.051	2.443SerGln: 2.443 ± 0.061	2.234SerArg: 2.234 ± 0.063	3.656SerSer: 3.656 ± 0.11	3.264SerThr: 3.264 ± 0.081	3.733SerVal: 3.733 ± 0.08	0.578SerTrp: 0.578 ± 0.028	2.533SerTyr: 2.533 ± 0.071	0.0SerXaa: 0.0 ± 0.0
Thr	3.469ThrAla: 3.469 ± 0.093	0.801ThrCys: 0.801 ± 0.036	3.143ThrAsp: 3.143 ± 0.071	2.697ThrGlu: 2.697 ± 0.063	2.47ThrPhe: 2.47 ± 0.064	3.986ThrGly: 3.986 ± 0.09	1.339ThrHis: 1.339 ± 0.044	5.189ThrIle: 5.189 ± 0.1	3.877ThrLys: 3.877 ± 0.076	5.072ThrLeu: 5.072 ± 0.108	1.635ThrMet: 1.635 ± 0.053	2.933ThrAsn: 2.933 ± 0.077	2.125ThrPro: 2.125 ± 0.06	2.116ThrGln: 2.116 ± 0.061	1.863ThrArg: 1.863 ± 0.054	3.494ThrSer: 3.494 ± 0.076	3.414ThrThr: 3.414 ± 0.113	3.785ThrVal: 3.785 ± 0.091	0.556ThrTrp: 0.556 ± 0.03	2.689ThrTyr: 2.689 ± 0.065	0.003ThrXaa: 0.003 ± 0.002
Val	4.655ValAla: 4.655 ± 0.096	1.224ValCys: 1.224 ± 0.042	4.528ValAsp: 4.528 ± 0.097	4.013ValGlu: 4.013 ± 0.083	2.832ValPhe: 2.832 ± 0.07	4.153ValGly: 4.153 ± 0.091	1.54ValHis: 1.54 ± 0.051	4.855ValIle: 4.855 ± 0.102	4.321ValLys: 4.321 ± 0.086	6.197ValLeu: 6.197 ± 0.123	1.888ValMet: 1.888 ± 0.057	2.912ValAsn: 2.912 ± 0.072	2.395ValPro: 2.395 ± 0.064	2.558ValGln: 2.558 ± 0.064	2.478ValArg: 2.478 ± 0.061	4.465ValSer: 4.465 ± 0.092	3.626ValThr: 3.626 ± 0.118	4.816ValVal: 4.816 ± 0.096	0.682ValTrp: 0.682 ± 0.038	2.657ValTyr: 2.657 ± 0.058	0.003ValXaa: 0.003 ± 0.002
Trp	0.578TrpAla: 0.578 ± 0.031	0.152TrpCys: 0.152 ± 0.016	0.527TrpAsp: 0.527 ± 0.029	0.526TrpGlu: 0.526 ± 0.032	0.477TrpPhe: 0.477 ± 0.028	0.523TrpGly: 0.523 ± 0.035	0.271TrpHis: 0.271 ± 0.021	1.008TrpIle: 1.008 ± 0.041	0.726TrpLys: 0.726 ± 0.037	0.855TrpLeu: 0.855 ± 0.044	0.444TrpMet: 0.444 ± 0.029	0.506TrpAsn: 0.506 ± 0.027	0.274TrpPro: 0.274 ± 0.023	0.493TrpGln: 0.493 ± 0.031	0.293TrpArg: 0.293 ± 0.022	0.475TrpSer: 0.475 ± 0.027	0.553TrpThr: 0.553 ± 0.029	0.527TrpVal: 0.527 ± 0.029	0.104TrpTrp: 0.104 ± 0.014	0.374TrpTyr: 0.374 ± 0.026	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.898TyrAla: 2.898 ± 0.078	0.688TyrCys: 0.688 ± 0.035	2.951TyrAsp: 2.951 ± 0.072	2.683TyrGlu: 2.683 ± 0.073	1.888TyrPhe: 1.888 ± 0.058	2.855TyrGly: 2.855 ± 0.071	1.114TyrHis: 1.114 ± 0.043	2.921TyrIle: 2.921 ± 0.065	2.323TyrLys: 2.323 ± 0.069	3.495TyrLeu: 3.495 ± 0.088	1.06TyrMet: 1.06 ± 0.041	1.676TyrAsn: 1.676 ± 0.06	1.575TyrPro: 1.575 ± 0.047	2.053TyrGln: 2.053 ± 0.052	1.931TyrArg: 1.931 ± 0.057	2.276TyrSer: 2.276 ± 0.058	2.492TyrThr: 2.492 ± 0.067	2.764TyrVal: 2.764 ± 0.07	0.401TyrTrp: 0.401 ± 0.027	1.894TyrTyr: 1.894 ± 0.066	0.003TyrXaa: 0.003 ± 0.002
Xaa	0.0XaaAla: 0.0 ± 0.0	0.002XaaCys: 0.002 ± 0.002	0.002XaaAsp: 0.002 ± 0.002	0.003XaaGlu: 0.003 ± 0.002	0.002XaaPhe: 0.002 ± 0.002	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.002XaaIle: 0.002 ± 0.002	0.003XaaLys: 0.003 ± 0.002	0.0XaaLeu: 0.0 ± 0.0	0.003XaaMet: 0.003 ± 0.002	0.0XaaAsn: 0.0 ± 0.0	0.003XaaPro: 0.003 ± 0.002	0.002XaaGln: 0.002 ± 0.002	0.0XaaArg: 0.0 ± 0.0	0.005XaaSer: 0.005 ± 0.003	0.003XaaThr: 0.003 ± 0.002	0.002XaaVal: 0.002 ± 0.002	0.002XaaTrp: 0.002 ± 0.002	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2184 proteins (652579 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---