Amino acid dipepetide frequency for Carnation ringspot virus (isolate Lommel) (CRSV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.838AlaAla: 6.838 ± 2.35
1.709AlaCys: 1.709 ± 0.841
1.709AlaAsp: 1.709 ± 1.113
0.57AlaGlu: 0.57 ± 0.61
1.709AlaPhe: 1.709 ± 1.03
2.279AlaGly: 2.279 ± 1.04
0.0AlaHis: 0.0 ± 0.0
5.698AlaIle: 5.698 ± 1.802
5.698AlaLys: 5.698 ± 1.629
3.419AlaLeu: 3.419 ± 0.928
3.989AlaMet: 3.989 ± 1.323
1.14AlaAsn: 1.14 ± 0.52
3.989AlaPro: 3.989 ± 1.218
1.709AlaGln: 1.709 ± 0.643
4.558AlaArg: 4.558 ± 0.862
2.279AlaSer: 2.279 ± 0.89
6.838AlaThr: 6.838 ± 1.01
8.547AlaVal: 8.547 ± 1.994
0.57AlaTrp: 0.57 ± 0.343
4.558AlaTyr: 4.558 ± 0.845
0.0AlaXaa: 0.0 ± 0.0
Cys
0.57CysAla: 0.57 ± 0.603
0.57CysCys: 0.57 ± 0.84
0.57CysAsp: 0.57 ± 0.343
0.57CysGlu: 0.57 ± 0.343
3.419CysPhe: 3.419 ± 1.576
1.709CysGly: 1.709 ± 0.927
0.57CysHis: 0.57 ± 0.61
1.709CysIle: 1.709 ± 0.788
1.14CysLys: 1.14 ± 0.554
2.849CysLeu: 2.849 ± 0.93
0.0CysMet: 0.0 ± 0.0
0.57CysAsn: 0.57 ± 0.343
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
3.419CysArg: 3.419 ± 1.088
1.14CysSer: 1.14 ± 0.687
1.709CysThr: 1.709 ± 1.809
2.279CysVal: 2.279 ± 1.026
0.0CysTrp: 0.0 ± 0.0
0.57CysTyr: 0.57 ± 0.343
0.0CysXaa: 0.0 ± 0.0
Asp
6.268AspAla: 6.268 ± 2.396
2.279AspCys: 2.279 ± 1.043
3.989AspAsp: 3.989 ± 0.69
2.849AspGlu: 2.849 ± 1.117
1.709AspPhe: 1.709 ± 0.788
3.419AspGly: 3.419 ± 1.273
1.14AspHis: 1.14 ± 0.624
2.849AspIle: 2.849 ± 1.379
4.558AspLys: 4.558 ± 1.557
6.268AspLeu: 6.268 ± 1.484
2.279AspMet: 2.279 ± 1.248
2.279AspAsn: 2.279 ± 1.432
0.0AspPro: 0.0 ± 0.0
1.709AspGln: 1.709 ± 0.788
2.279AspArg: 2.279 ± 1.66
5.698AspSer: 5.698 ± 1.212
2.279AspThr: 2.279 ± 1.082
5.698AspVal: 5.698 ± 3.383
1.709AspTrp: 1.709 ± 1.113
2.279AspTyr: 2.279 ± 1.487
0.0AspXaa: 0.0 ± 0.0
Glu
4.558GluAla: 4.558 ± 0.862
3.989GluCys: 3.989 ± 1.816
5.698GluAsp: 5.698 ± 2.758
3.419GluGlu: 3.419 ± 1.576
0.57GluPhe: 0.57 ± 0.343
2.849GluGly: 2.849 ± 0.656
1.709GluHis: 1.709 ± 0.788
1.709GluIle: 1.709 ± 0.788
2.849GluLys: 2.849 ± 1.717
2.279GluLeu: 2.279 ± 0.507
0.0GluMet: 0.0 ± 0.0
0.57GluAsn: 0.57 ± 0.343
3.989GluPro: 3.989 ± 1.218
0.57GluGln: 0.57 ± 0.343
0.57GluArg: 0.57 ± 0.343
4.558GluSer: 4.558 ± 0.61
1.709GluThr: 1.709 ± 0.526
3.419GluVal: 3.419 ± 0.409
1.709GluTrp: 1.709 ± 0.788
1.709GluTyr: 1.709 ± 0.788
0.0GluXaa: 0.0 ± 0.0
Phe
2.279PheAla: 2.279 ± 1.759
1.709PheCys: 1.709 ± 0.837
5.128PheAsp: 5.128 ± 1.515
2.849PheGlu: 2.849 ± 1.379
0.57PhePhe: 0.57 ± 0.84
2.279PheGly: 2.279 ± 1.043
0.0PheHis: 0.0 ± 0.0
0.57PheIle: 0.57 ± 0.343
1.709PheLys: 1.709 ± 0.788
2.279PheLeu: 2.279 ± 1.043
1.709PheMet: 1.709 ± 0.645
2.849PheAsn: 2.849 ± 0.832
2.279PhePro: 2.279 ± 1.04
0.57PheGln: 0.57 ± 0.61
3.989PheArg: 3.989 ± 1.422
6.838PheSer: 6.838 ± 1.312
1.709PheThr: 1.709 ± 1.809
2.279PheVal: 2.279 ± 1.247
1.14PheTrp: 1.14 ± 0.624
1.14PheTyr: 1.14 ± 0.554
0.0PheXaa: 0.0 ± 0.0
Gly
2.849GlyAla: 2.849 ± 0.656
0.0GlyCys: 0.0 ± 0.0
3.989GlyAsp: 3.989 ± 0.69
2.849GlyGlu: 2.849 ± 0.863
3.989GlyPhe: 3.989 ± 1.02
2.849GlyGly: 2.849 ± 1.579
0.0GlyHis: 0.0 ± 0.0
4.558GlyIle: 4.558 ± 0.971
1.14GlyLys: 1.14 ± 0.624
6.268GlyLeu: 6.268 ± 2.294
1.14GlyMet: 1.14 ± 0.624
2.279GlyAsn: 2.279 ± 1.107
2.279GlyPro: 2.279 ± 0.986
2.849GlyGln: 2.849 ± 0.849
3.989GlyArg: 3.989 ± 0.899
5.128GlySer: 5.128 ± 1.552
2.849GlyThr: 2.849 ± 1.925
4.558GlyVal: 4.558 ± 1.882
0.0GlyTrp: 0.0 ± 0.0
0.57GlyTyr: 0.57 ± 0.343
0.0GlyXaa: 0.0 ± 0.0
His
1.14HisAla: 1.14 ± 0.554
0.57HisCys: 0.57 ± 0.343
0.57HisAsp: 0.57 ± 0.603
1.14HisGlu: 1.14 ± 0.624
1.14HisPhe: 1.14 ± 0.624
0.0HisGly: 0.0 ± 0.0
1.709HisHis: 1.709 ± 0.642
0.0HisIle: 0.0 ± 0.0
2.279HisLys: 2.279 ± 1.026
0.57HisLeu: 0.57 ± 0.61
1.709HisMet: 1.709 ± 0.788
0.57HisAsn: 0.57 ± 0.343
0.57HisPro: 0.57 ± 0.61
1.709HisGln: 1.709 ± 1.593
0.57HisArg: 0.57 ± 0.343
1.14HisSer: 1.14 ± 0.52
1.14HisThr: 1.14 ± 0.624
0.57HisVal: 0.57 ± 0.61
0.57HisTrp: 0.57 ± 0.343
0.57HisTyr: 0.57 ± 0.343
0.0HisXaa: 0.0 ± 0.0
Ile
1.709IleAla: 1.709 ± 1.113
2.279IleCys: 2.279 ± 1.248
6.268IleAsp: 6.268 ± 1.357
2.849IleGlu: 2.849 ± 0.799
2.849IlePhe: 2.849 ± 0.91
2.279IleGly: 2.279 ± 0.89
0.57IleHis: 0.57 ± 0.61
1.709IleIle: 1.709 ± 0.788
3.419IleLys: 3.419 ± 0.409
4.558IleLeu: 4.558 ± 1.312
1.14IleMet: 1.14 ± 0.624
3.419IleAsn: 3.419 ± 1.125
2.849IlePro: 2.849 ± 1.241
0.57IleGln: 0.57 ± 0.343
2.279IleArg: 2.279 ± 1.027
5.128IleSer: 5.128 ± 0.83
2.849IleThr: 2.849 ± 2.336
2.849IleVal: 2.849 ± 0.832
0.0IleTrp: 0.0 ± 0.0
1.14IleTyr: 1.14 ± 0.624
0.0IleXaa: 0.0 ± 0.0
Lys
1.709LysAla: 1.709 ± 1.03
0.57LysCys: 0.57 ± 0.61
3.419LysAsp: 3.419 ± 1.16
0.57LysGlu: 0.57 ± 0.343
3.419LysPhe: 3.419 ± 1.243
3.419LysGly: 3.419 ± 0.928
1.14LysHis: 1.14 ± 0.624
4.558LysIle: 4.558 ± 0.936
4.558LysLys: 4.558 ± 1.559
6.838LysLeu: 6.838 ± 1.472
2.279LysMet: 2.279 ± 0.869
2.849LysAsn: 2.849 ± 1.022
1.709LysPro: 1.709 ± 0.927
2.279LysGln: 2.279 ± 1.013
7.407LysArg: 7.407 ± 2.391
7.407LysSer: 7.407 ± 1.232
4.558LysThr: 4.558 ± 1.953
2.279LysVal: 2.279 ± 0.89
2.279LysTrp: 2.279 ± 1.043
1.709LysTyr: 1.709 ± 0.691
0.0LysXaa: 0.0 ± 0.0
Leu
3.989LeuAla: 3.989 ± 2.25
1.14LeuCys: 1.14 ± 0.687
4.558LeuAsp: 4.558 ± 1.01
5.698LeuGlu: 5.698 ± 2.598
3.419LeuPhe: 3.419 ± 1.072
5.698LeuGly: 5.698 ± 1.577
2.279LeuHis: 2.279 ± 1.374
1.14LeuIle: 1.14 ± 0.743
4.558LeuLys: 4.558 ± 0.715
4.558LeuLeu: 4.558 ± 0.715
3.419LeuMet: 3.419 ± 0.409
5.128LeuAsn: 5.128 ± 0.864
3.989LeuPro: 3.989 ± 1.498
0.57LeuGln: 0.57 ± 0.603
3.989LeuArg: 3.989 ± 1.425
10.826LeuSer: 10.826 ± 2.233
0.57LeuThr: 0.57 ± 0.61
9.687LeuVal: 9.687 ± 1.841
0.57LeuTrp: 0.57 ± 0.343
2.279LeuTyr: 2.279 ± 0.782
0.0LeuXaa: 0.0 ± 0.0
Met
4.558MetAla: 4.558 ± 0.845
0.57MetCys: 0.57 ± 0.343
3.419MetAsp: 3.419 ± 1.285
0.57MetGlu: 0.57 ± 0.343
0.0MetPhe: 0.0 ± 0.0
2.279MetGly: 2.279 ± 1.248
0.0MetHis: 0.0 ± 0.0
3.419MetIle: 3.419 ± 1.181
1.709MetLys: 1.709 ± 0.642
1.14MetLeu: 1.14 ± 0.765
0.0MetMet: 0.0 ± 0.0
1.14MetAsn: 1.14 ± 0.554
2.849MetPro: 2.849 ± 1.379
0.0MetGln: 0.0 ± 0.0
1.14MetArg: 1.14 ± 1.22
1.14MetSer: 1.14 ± 0.52
2.279MetThr: 2.279 ± 1.082
2.279MetVal: 2.279 ± 0.89
0.57MetTrp: 0.57 ± 0.603
1.14MetTyr: 1.14 ± 0.52
0.0MetXaa: 0.0 ± 0.0
Asn
1.709AsnAla: 1.709 ± 0.643
0.0AsnCys: 0.0 ± 0.0
1.14AsnAsp: 1.14 ± 0.687
5.128AsnGlu: 5.128 ± 1.515
3.419AsnPhe: 3.419 ± 1.181
2.849AsnGly: 2.849 ± 0.849
0.57AsnHis: 0.57 ± 0.61
1.709AsnIle: 1.709 ± 0.645
1.709AsnLys: 1.709 ± 0.691
2.849AsnLeu: 2.849 ± 0.779
2.849AsnMet: 2.849 ± 1.12
2.849AsnAsn: 2.849 ± 0.307
3.989AsnPro: 3.989 ± 0.82
0.57AsnGln: 0.57 ± 0.603
3.989AsnArg: 3.989 ± 0.549
1.14AsnSer: 1.14 ± 0.743
0.57AsnThr: 0.57 ± 0.343
1.709AsnVal: 1.709 ± 1.219
0.57AsnTrp: 0.57 ± 0.343
1.14AsnTyr: 1.14 ± 0.743
0.0AsnXaa: 0.0 ± 0.0
Pro
1.709ProAla: 1.709 ± 0.973
0.57ProCys: 0.57 ± 0.61
2.849ProAsp: 2.849 ± 0.863
1.14ProGlu: 1.14 ± 0.52
1.14ProPhe: 1.14 ± 1.22
2.279ProGly: 2.279 ± 1.086
0.0ProHis: 0.0 ± 0.0
1.709ProIle: 1.709 ± 0.526
5.698ProLys: 5.698 ± 1.417
2.279ProLeu: 2.279 ± 0.679
0.57ProMet: 0.57 ± 0.572
2.279ProAsn: 2.279 ± 1.759
2.849ProPro: 2.849 ± 1.548
4.558ProGln: 4.558 ± 0.862
5.128ProArg: 5.128 ± 0.516
5.128ProSer: 5.128 ± 2.525
4.558ProThr: 4.558 ± 1.523
4.558ProVal: 4.558 ± 2.16
0.0ProTrp: 0.0 ± 0.0
1.14ProTyr: 1.14 ± 0.52
0.0ProXaa: 0.0 ± 0.0
Gln
2.849GlnAla: 2.849 ± 0.93
1.14GlnCys: 1.14 ± 0.52
0.57GlnAsp: 0.57 ± 0.603
2.849GlnGlu: 2.849 ± 1.11
1.14GlnPhe: 1.14 ± 1.206
1.14GlnGly: 1.14 ± 0.554
0.57GlnHis: 0.57 ± 0.343
3.419GlnIle: 3.419 ± 1.5
0.57GlnLys: 0.57 ± 0.343
3.989GlnLeu: 3.989 ± 1.494
0.57GlnMet: 0.57 ± 0.343
1.14GlnAsn: 1.14 ± 0.52
2.849GlnPro: 2.849 ± 1.117
1.14GlnGln: 1.14 ± 0.624
1.709GlnArg: 1.709 ± 0.643
2.279GlnSer: 2.279 ± 0.941
1.14GlnThr: 1.14 ± 0.52
1.14GlnVal: 1.14 ± 0.743
0.0GlnTrp: 0.0 ± 0.0
1.709GlnTyr: 1.709 ± 1.219
0.0GlnXaa: 0.0 ± 0.0
Arg
5.128ArgAla: 5.128 ± 1.815
2.849ArgCys: 2.849 ± 0.307
5.128ArgAsp: 5.128 ± 0.864
2.279ArgGlu: 2.279 ± 1.026
2.849ArgPhe: 2.849 ± 0.99
0.57ArgGly: 0.57 ± 0.343
2.849ArgHis: 2.849 ± 1.763
7.407ArgIle: 7.407 ± 2.325
4.558ArgLys: 4.558 ± 1.234
4.558ArgLeu: 4.558 ± 1.35
2.849ArgMet: 2.849 ± 1.204
2.279ArgAsn: 2.279 ± 0.925
1.14ArgPro: 1.14 ± 0.554
4.558ArgGln: 4.558 ± 2.743
3.419ArgArg: 3.419 ± 2.563
2.279ArgSer: 2.279 ± 1.107
4.558ArgThr: 4.558 ± 1.43
6.838ArgVal: 6.838 ± 1.618
0.0ArgTrp: 0.0 ± 0.0
4.558ArgTyr: 4.558 ± 1.36
0.0ArgXaa: 0.0 ± 0.0
Ser
4.558SerAla: 4.558 ± 1.679
0.57SerCys: 0.57 ± 0.603
3.989SerAsp: 3.989 ± 1.542
3.419SerGlu: 3.419 ± 0.928
3.989SerPhe: 3.989 ± 1.323
5.698SerGly: 5.698 ± 2.637
0.57SerHis: 0.57 ± 0.343
4.558SerIle: 4.558 ± 0.936
6.838SerLys: 6.838 ± 2.671
10.826SerLeu: 10.826 ± 1.861
3.419SerMet: 3.419 ± 0.674
2.849SerAsn: 2.849 ± 1.925
3.989SerPro: 3.989 ± 0.621
2.849SerGln: 2.849 ± 0.99
6.838SerArg: 6.838 ± 1.973
6.838SerSer: 6.838 ± 1.89
3.419SerThr: 3.419 ± 1.391
6.268SerVal: 6.268 ± 3.634
2.279SerTrp: 2.279 ± 0.679
2.279SerTyr: 2.279 ± 0.782
0.0SerXaa: 0.0 ± 0.0
Thr
5.698ThrAla: 5.698 ± 2.458
0.57ThrCys: 0.57 ± 0.603
2.849ThrAsp: 2.849 ± 1.789
1.14ThrGlu: 1.14 ± 0.554
2.279ThrPhe: 2.279 ± 1.013
3.989ThrGly: 3.989 ± 0.562
1.14ThrHis: 1.14 ± 0.554
1.14ThrIle: 1.14 ± 0.52
3.419ThrLys: 3.419 ± 0.704
3.419ThrLeu: 3.419 ± 1.882
1.709ThrMet: 1.709 ± 1.169
2.849ThrAsn: 2.849 ± 0.896
5.128ThrPro: 5.128 ± 1.344
1.14ThrGln: 1.14 ± 0.52
5.698ThrArg: 5.698 ± 1.659
3.419ThrSer: 3.419 ± 2.144
4.558ThrThr: 4.558 ± 2.728
2.849ThrVal: 2.849 ± 1.548
0.57ThrTrp: 0.57 ± 0.84
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.128ValAla: 5.128 ± 1.515
2.279ValCys: 2.279 ± 1.026
3.989ValAsp: 3.989 ± 0.988
6.838ValGlu: 6.838 ± 2.249
1.709ValPhe: 1.709 ± 1.03
6.268ValGly: 6.268 ± 3.302
3.419ValHis: 3.419 ± 0.84
2.849ValIle: 2.849 ± 2.122
4.558ValLys: 4.558 ± 1.523
4.558ValLeu: 4.558 ± 1.882
0.0ValMet: 0.0 ± 0.0
1.14ValAsn: 1.14 ± 0.52
5.698ValPro: 5.698 ± 1.247
2.849ValGln: 2.849 ± 1.241
4.558ValArg: 4.558 ± 0.936
9.117ValSer: 9.117 ± 3.053
3.989ValThr: 3.989 ± 1.636
7.977ValVal: 7.977 ± 2.316
1.709ValTrp: 1.709 ± 0.645
1.14ValTyr: 1.14 ± 1.206
0.0ValXaa: 0.0 ± 0.0
Trp
1.709TrpAla: 1.709 ± 0.788
0.0TrpCys: 0.0 ± 0.0
1.14TrpAsp: 1.14 ± 1.206
0.0TrpGlu: 0.0 ± 0.0
1.709TrpPhe: 1.709 ± 0.788
1.709TrpGly: 1.709 ± 0.642
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.14TrpLys: 1.14 ± 0.554
1.14TrpLeu: 1.14 ± 0.554
0.0TrpMet: 0.0 ± 0.0
1.14TrpAsn: 1.14 ± 0.624
0.0TrpPro: 0.0 ± 0.0
0.57TrpGln: 0.57 ± 0.343
2.279TrpArg: 2.279 ± 0.782
1.709TrpSer: 1.709 ± 0.691
0.0TrpThr: 0.0 ± 0.0
1.14TrpVal: 1.14 ± 0.624
0.57TrpTrp: 0.57 ± 0.84
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.849TyrAla: 2.849 ± 0.307
0.0TyrCys: 0.0 ± 0.0
0.57TyrAsp: 0.57 ± 0.603
1.709TyrGlu: 1.709 ± 1.072
2.849TyrPhe: 2.849 ± 1.117
0.57TyrGly: 0.57 ± 0.603
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
2.849TyrLys: 2.849 ± 1.641
3.419TyrLeu: 3.419 ± 1.086
0.0TyrMet: 0.0 ± 0.0
1.709TyrAsn: 1.709 ± 0.788
0.0TyrPro: 0.0 ± 0.0
1.14TyrGln: 1.14 ± 0.687
2.849TyrArg: 2.849 ± 0.832
2.849TyrSer: 2.849 ± 1.186
2.279TyrThr: 2.279 ± 1.778
2.849TyrVal: 2.849 ± 2.086
1.14TyrTrp: 1.14 ± 0.743
0.57TyrTyr: 0.57 ± 0.61
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1756 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski