Amino acid dipepetide frequency for Halorubrum pleomorphic virus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
20.295AlaAla: 20.295 ± 3.6
0.738AlaCys: 0.738 ± 0.824
8.487AlaAsp: 8.487 ± 1.422
7.38AlaGlu: 7.38 ± 1.597
2.583AlaPhe: 2.583 ± 1.05
10.701AlaGly: 10.701 ± 2.287
0.369AlaHis: 0.369 ± 0.292
4.059AlaIle: 4.059 ± 1.446
3.321AlaLys: 3.321 ± 0.962
9.963AlaLeu: 9.963 ± 1.801
1.476AlaMet: 1.476 ± 0.581
3.321AlaAsn: 3.321 ± 0.976
2.952AlaPro: 2.952 ± 0.733
2.952AlaGln: 2.952 ± 0.879
6.273AlaArg: 6.273 ± 1.108
5.535AlaSer: 5.535 ± 0.999
5.166AlaThr: 5.166 ± 0.978
8.118AlaVal: 8.118 ± 2.072
1.845AlaTrp: 1.845 ± 0.776
3.69AlaTyr: 3.69 ± 1.132
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.369CysCys: 0.369 ± 0.349
0.369CysAsp: 0.369 ± 0.378
0.738CysGlu: 0.738 ± 0.755
0.0CysPhe: 0.0 ± 0.0
0.369CysGly: 0.369 ± 0.349
0.369CysHis: 0.369 ± 0.287
0.0CysIle: 0.0 ± 0.0
0.369CysLys: 0.369 ± 0.351
0.0CysLeu: 0.0 ± 0.0
0.369CysMet: 0.369 ± 0.388
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.369CysGln: 0.369 ± 0.287
0.369CysArg: 0.369 ± 0.378
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.107CysVal: 1.107 ± 0.945
0.369CysTrp: 0.369 ± 0.399
0.738CysTyr: 0.738 ± 0.518
0.0CysXaa: 0.0 ± 0.0
Asp
6.273AspAla: 6.273 ± 1.278
0.0AspCys: 0.0 ± 0.0
6.642AspAsp: 6.642 ± 1.834
5.166AspGlu: 5.166 ± 1.317
2.214AspPhe: 2.214 ± 0.778
5.535AspGly: 5.535 ± 1.477
1.845AspHis: 1.845 ± 1.437
6.273AspIle: 6.273 ± 1.594
2.952AspLys: 2.952 ± 0.776
2.214AspLeu: 2.214 ± 1.006
4.059AspMet: 4.059 ± 1.377
3.69AspAsn: 3.69 ± 1.01
2.952AspPro: 2.952 ± 0.994
2.952AspGln: 2.952 ± 0.894
5.166AspArg: 5.166 ± 1.05
4.797AspSer: 4.797 ± 1.09
5.166AspThr: 5.166 ± 0.968
3.69AspVal: 3.69 ± 1.314
1.107AspTrp: 1.107 ± 0.768
4.428AspTyr: 4.428 ± 0.795
0.0AspXaa: 0.0 ± 0.0
Glu
8.487GluAla: 8.487 ± 1.875
0.738GluCys: 0.738 ± 0.516
5.166GluAsp: 5.166 ± 1.445
6.273GluGlu: 6.273 ± 2.513
1.845GluPhe: 1.845 ± 0.593
6.273GluGly: 6.273 ± 1.4
0.738GluHis: 0.738 ± 0.322
4.797GluIle: 4.797 ± 1.166
3.69GluLys: 3.69 ± 1.416
6.642GluLeu: 6.642 ± 1.396
2.214GluMet: 2.214 ± 0.73
1.845GluAsn: 1.845 ± 0.764
1.476GluPro: 1.476 ± 0.569
3.69GluGln: 3.69 ± 1.191
4.059GluArg: 4.059 ± 0.893
6.273GluSer: 6.273 ± 1.987
7.38GluThr: 7.38 ± 1.514
2.583GluVal: 2.583 ± 1.077
1.845GluTrp: 1.845 ± 0.715
2.952GluTyr: 2.952 ± 1.083
0.0GluXaa: 0.0 ± 0.0
Phe
1.845PheAla: 1.845 ± 0.773
0.369PheCys: 0.369 ± 0.287
2.583PheAsp: 2.583 ± 1.333
2.952PheGlu: 2.952 ± 1.777
1.107PhePhe: 1.107 ± 0.597
2.583PheGly: 2.583 ± 1.127
0.369PheHis: 0.369 ± 0.287
1.107PheIle: 1.107 ± 0.305
0.738PheLys: 0.738 ± 0.597
1.476PheLeu: 1.476 ± 0.517
0.0PheMet: 0.0 ± 0.0
0.738PheAsn: 0.738 ± 0.398
0.738PhePro: 0.738 ± 0.449
0.0PheGln: 0.0 ± 0.0
0.738PheArg: 0.738 ± 0.417
2.583PheSer: 2.583 ± 0.751
2.583PheThr: 2.583 ± 0.925
2.583PheVal: 2.583 ± 1.102
0.369PheTrp: 0.369 ± 0.388
0.738PheTyr: 0.738 ± 0.439
0.0PheXaa: 0.0 ± 0.0
Gly
8.856GlyAla: 8.856 ± 2.001
0.369GlyCys: 0.369 ± 0.349
5.904GlyAsp: 5.904 ± 1.65
5.166GlyGlu: 5.166 ± 0.961
3.69GlyPhe: 3.69 ± 0.809
9.963GlyGly: 9.963 ± 3.16
1.845GlyHis: 1.845 ± 0.803
3.69GlyIle: 3.69 ± 0.963
1.845GlyLys: 1.845 ± 0.773
7.38GlyLeu: 7.38 ± 1.857
1.476GlyMet: 1.476 ± 0.794
2.952GlyAsn: 2.952 ± 0.774
3.321GlyPro: 3.321 ± 1.053
1.476GlyGln: 1.476 ± 0.759
4.059GlyArg: 4.059 ± 1.227
8.487GlySer: 8.487 ± 2.065
3.69GlyThr: 3.69 ± 1.509
5.535GlyVal: 5.535 ± 1.494
1.107GlyTrp: 1.107 ± 0.55
4.428GlyTyr: 4.428 ± 0.933
0.0GlyXaa: 0.0 ± 0.0
His
1.476HisAla: 1.476 ± 0.449
0.0HisCys: 0.0 ± 0.0
1.107HisAsp: 1.107 ± 0.862
1.107HisGlu: 1.107 ± 0.447
0.0HisPhe: 0.0 ± 0.0
2.583HisGly: 2.583 ± 1.05
0.738HisHis: 0.738 ± 0.459
1.845HisIle: 1.845 ± 0.803
0.369HisLys: 0.369 ± 0.388
1.107HisLeu: 1.107 ± 0.578
0.369HisMet: 0.369 ± 0.292
0.0HisAsn: 0.0 ± 0.0
1.107HisPro: 1.107 ± 0.862
0.0HisGln: 0.0 ± 0.0
0.738HisArg: 0.738 ± 0.448
0.369HisSer: 0.369 ± 0.292
1.476HisThr: 1.476 ± 0.658
0.738HisVal: 0.738 ± 0.575
0.0HisTrp: 0.0 ± 0.0
1.476HisTyr: 1.476 ± 0.913
0.0HisXaa: 0.0 ± 0.0
Ile
5.535IleAla: 5.535 ± 1.223
0.369IleCys: 0.369 ± 0.388
3.321IleAsp: 3.321 ± 0.704
3.69IleGlu: 3.69 ± 0.876
0.369IlePhe: 0.369 ± 0.292
4.797IleGly: 4.797 ± 2.112
0.738IleHis: 0.738 ± 0.575
1.845IleIle: 1.845 ± 1.032
1.476IleLys: 1.476 ± 1.0
2.583IleLeu: 2.583 ± 0.944
0.369IleMet: 0.369 ± 0.271
1.476IleAsn: 1.476 ± 0.843
2.583IlePro: 2.583 ± 1.163
0.738IleGln: 0.738 ± 0.356
3.69IleArg: 3.69 ± 1.16
4.059IleSer: 4.059 ± 0.879
2.952IleThr: 2.952 ± 1.118
4.797IleVal: 4.797 ± 1.128
1.107IleTrp: 1.107 ± 0.632
2.214IleTyr: 2.214 ± 0.498
0.0IleXaa: 0.0 ± 0.0
Lys
2.952LysAla: 2.952 ± 1.056
0.738LysCys: 0.738 ± 0.417
1.845LysAsp: 1.845 ± 0.68
3.321LysGlu: 3.321 ± 0.625
1.476LysPhe: 1.476 ± 0.904
2.952LysGly: 2.952 ± 0.642
0.738LysHis: 0.738 ± 0.322
2.583LysIle: 2.583 ± 1.099
1.845LysLys: 1.845 ± 0.706
0.738LysLeu: 0.738 ± 0.575
1.107LysMet: 1.107 ± 0.579
1.107LysAsn: 1.107 ± 0.585
1.845LysPro: 1.845 ± 0.538
1.107LysGln: 1.107 ± 0.82
2.583LysArg: 2.583 ± 1.22
1.845LysSer: 1.845 ± 0.728
2.214LysThr: 2.214 ± 0.897
1.476LysVal: 1.476 ± 0.589
1.107LysTrp: 1.107 ± 0.623
1.107LysTyr: 1.107 ± 0.585
0.0LysXaa: 0.0 ± 0.0
Leu
6.273LeuAla: 6.273 ± 0.894
0.369LeuCys: 0.369 ± 0.378
5.166LeuAsp: 5.166 ± 1.288
4.428LeuGlu: 4.428 ± 0.77
2.583LeuPhe: 2.583 ± 1.295
6.273LeuGly: 6.273 ± 1.2
0.369LeuHis: 0.369 ± 0.292
2.952LeuIle: 2.952 ± 0.79
2.583LeuLys: 2.583 ± 1.057
8.118LeuLeu: 8.118 ± 2.018
0.738LeuMet: 0.738 ± 0.628
3.321LeuAsn: 3.321 ± 0.904
2.583LeuPro: 2.583 ± 0.985
2.214LeuGln: 2.214 ± 0.894
4.797LeuArg: 4.797 ± 1.393
5.904LeuSer: 5.904 ± 1.534
4.428LeuThr: 4.428 ± 1.448
8.487LeuVal: 8.487 ± 2.159
1.845LeuTrp: 1.845 ± 0.988
1.107LeuTyr: 1.107 ± 0.545
0.0LeuXaa: 0.0 ± 0.0
Met
2.583MetAla: 2.583 ± 1.127
0.369MetCys: 0.369 ± 0.349
1.845MetAsp: 1.845 ± 0.5
0.738MetGlu: 0.738 ± 0.701
0.0MetPhe: 0.0 ± 0.0
1.845MetGly: 1.845 ± 0.885
0.0MetHis: 0.0 ± 0.0
0.369MetIle: 0.369 ± 0.287
1.476MetLys: 1.476 ± 0.659
1.107MetLeu: 1.107 ± 0.557
0.0MetMet: 0.0 ± 0.0
1.476MetAsn: 1.476 ± 0.662
0.369MetPro: 0.369 ± 0.369
0.369MetGln: 0.369 ± 0.416
1.107MetArg: 1.107 ± 0.474
2.214MetSer: 2.214 ± 0.947
4.428MetThr: 4.428 ± 1.046
1.107MetVal: 1.107 ± 0.664
0.0MetTrp: 0.0 ± 0.0
0.369MetTyr: 0.369 ± 0.287
0.0MetXaa: 0.0 ± 0.0
Asn
3.69AsnAla: 3.69 ± 0.699
0.0AsnCys: 0.0 ± 0.0
3.69AsnAsp: 3.69 ± 1.411
1.476AsnGlu: 1.476 ± 0.447
0.0AsnPhe: 0.0 ± 0.0
4.797AsnGly: 4.797 ± 1.736
0.369AsnHis: 0.369 ± 0.369
1.476AsnIle: 1.476 ± 0.634
1.107AsnLys: 1.107 ± 0.678
2.214AsnLeu: 2.214 ± 1.188
1.107AsnMet: 1.107 ± 0.578
1.107AsnAsn: 1.107 ± 0.594
2.952AsnPro: 2.952 ± 0.667
0.0AsnGln: 0.0 ± 0.0
1.845AsnArg: 1.845 ± 0.738
2.214AsnSer: 2.214 ± 0.755
2.214AsnThr: 2.214 ± 0.899
3.69AsnVal: 3.69 ± 0.863
1.476AsnTrp: 1.476 ± 0.727
1.107AsnTyr: 1.107 ± 0.594
0.0AsnXaa: 0.0 ± 0.0
Pro
5.535ProAla: 5.535 ± 1.428
0.0ProCys: 0.0 ± 0.0
3.69ProAsp: 3.69 ± 0.718
3.321ProGlu: 3.321 ± 1.033
0.738ProPhe: 0.738 ± 0.452
3.69ProGly: 3.69 ± 0.95
0.369ProHis: 0.369 ± 0.287
1.845ProIle: 1.845 ± 0.744
1.476ProLys: 1.476 ± 0.57
1.107ProLeu: 1.107 ± 0.475
1.107ProMet: 1.107 ± 0.493
0.369ProAsn: 0.369 ± 0.349
1.476ProPro: 1.476 ± 0.526
0.738ProGln: 0.738 ± 0.459
1.476ProArg: 1.476 ± 0.944
1.845ProSer: 1.845 ± 0.373
2.952ProThr: 2.952 ± 0.877
4.059ProVal: 4.059 ± 1.453
0.0ProTrp: 0.0 ± 0.0
1.476ProTyr: 1.476 ± 0.709
0.0ProXaa: 0.0 ± 0.0
Gln
2.952GlnAla: 2.952 ± 1.042
0.0GlnCys: 0.0 ± 0.0
1.107GlnAsp: 1.107 ± 0.591
1.845GlnGlu: 1.845 ± 0.494
1.476GlnPhe: 1.476 ± 0.511
0.369GlnGly: 0.369 ± 0.348
1.476GlnHis: 1.476 ± 0.592
1.845GlnIle: 1.845 ± 0.529
2.214GlnLys: 2.214 ± 0.994
2.214GlnLeu: 2.214 ± 0.7
0.738GlnMet: 0.738 ± 0.596
1.476GlnAsn: 1.476 ± 0.738
0.738GlnPro: 0.738 ± 0.49
0.738GlnGln: 0.738 ± 0.38
1.476GlnArg: 1.476 ± 0.606
2.214GlnSer: 2.214 ± 0.698
1.845GlnThr: 1.845 ± 0.719
1.107GlnVal: 1.107 ± 0.486
0.0GlnTrp: 0.0 ± 0.0
0.738GlnTyr: 0.738 ± 0.488
0.0GlnXaa: 0.0 ± 0.0
Arg
3.69ArgAla: 3.69 ± 0.873
0.369ArgCys: 0.369 ± 0.399
4.797ArgAsp: 4.797 ± 1.448
7.011ArgGlu: 7.011 ± 1.478
0.0ArgPhe: 0.0 ± 0.0
1.845ArgGly: 1.845 ± 0.638
0.738ArgHis: 0.738 ± 0.696
2.214ArgIle: 2.214 ± 1.37
1.476ArgLys: 1.476 ± 0.669
6.642ArgLeu: 6.642 ± 1.514
1.107ArgMet: 1.107 ± 0.503
2.214ArgAsn: 2.214 ± 0.447
2.952ArgPro: 2.952 ± 1.111
1.845ArgGln: 1.845 ± 0.668
5.166ArgArg: 5.166 ± 1.591
3.69ArgSer: 3.69 ± 0.941
4.428ArgThr: 4.428 ± 1.126
3.69ArgVal: 3.69 ± 1.139
1.107ArgTrp: 1.107 ± 0.578
1.845ArgTyr: 1.845 ± 0.82
0.0ArgXaa: 0.0 ± 0.0
Ser
6.273SerAla: 6.273 ± 2.469
0.738SerCys: 0.738 ± 0.576
6.642SerAsp: 6.642 ± 1.362
6.642SerGlu: 6.642 ± 1.69
2.583SerPhe: 2.583 ± 0.74
5.166SerGly: 5.166 ± 1.001
1.845SerHis: 1.845 ± 1.18
5.535SerIle: 5.535 ± 1.037
2.214SerLys: 2.214 ± 0.634
4.428SerLeu: 4.428 ± 1.306
1.107SerMet: 1.107 ± 0.539
2.214SerAsn: 2.214 ± 0.61
2.583SerPro: 2.583 ± 0.885
1.107SerGln: 1.107 ± 0.781
3.321SerArg: 3.321 ± 0.714
3.69SerSer: 3.69 ± 1.079
4.428SerThr: 4.428 ± 1.085
5.166SerVal: 5.166 ± 1.418
0.369SerTrp: 0.369 ± 0.348
2.952SerTyr: 2.952 ± 0.963
0.0SerXaa: 0.0 ± 0.0
Thr
7.749ThrAla: 7.749 ± 2.17
0.0ThrCys: 0.0 ± 0.0
4.428ThrAsp: 4.428 ± 1.15
8.118ThrGlu: 8.118 ± 1.211
2.214ThrPhe: 2.214 ± 0.815
6.273ThrGly: 6.273 ± 1.39
1.107ThrHis: 1.107 ± 0.599
3.69ThrIle: 3.69 ± 0.727
1.476ThrLys: 1.476 ± 0.583
5.904ThrLeu: 5.904 ± 1.22
2.214ThrMet: 2.214 ± 0.836
2.952ThrAsn: 2.952 ± 1.052
1.845ThrPro: 1.845 ± 0.62
2.214ThrGln: 2.214 ± 0.77
2.214ThrArg: 2.214 ± 0.747
4.797ThrSer: 4.797 ± 1.658
4.428ThrThr: 4.428 ± 0.819
4.797ThrVal: 4.797 ± 1.465
0.369ThrTrp: 0.369 ± 0.292
1.476ThrTyr: 1.476 ± 0.63
0.0ThrXaa: 0.0 ± 0.0
Val
10.701ValAla: 10.701 ± 2.949
0.369ValCys: 0.369 ± 0.378
5.535ValAsp: 5.535 ± 1.863
4.428ValGlu: 4.428 ± 1.391
1.476ValPhe: 1.476 ± 0.807
5.535ValGly: 5.535 ± 1.812
1.476ValHis: 1.476 ± 0.662
2.214ValIle: 2.214 ± 0.992
2.214ValLys: 2.214 ± 1.132
7.38ValLeu: 7.38 ± 2.64
1.107ValMet: 1.107 ± 0.691
3.69ValAsn: 3.69 ± 0.911
2.214ValPro: 2.214 ± 0.539
2.583ValGln: 2.583 ± 0.846
4.428ValArg: 4.428 ± 1.011
6.273ValSer: 6.273 ± 1.012
4.428ValThr: 4.428 ± 0.894
6.273ValVal: 6.273 ± 1.479
0.738ValTrp: 0.738 ± 0.701
1.476ValTyr: 1.476 ± 0.588
0.0ValXaa: 0.0 ± 0.0
Trp
0.369TrpAla: 0.369 ± 0.388
0.0TrpCys: 0.0 ± 0.0
2.583TrpAsp: 2.583 ± 0.549
0.738TrpGlu: 0.738 ± 0.701
0.0TrpPhe: 0.0 ± 0.0
1.476TrpGly: 1.476 ± 0.649
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.369TrpLys: 0.369 ± 0.287
1.476TrpLeu: 1.476 ± 0.631
0.369TrpMet: 0.369 ± 0.416
1.107TrpAsn: 1.107 ± 0.497
1.107TrpPro: 1.107 ± 0.561
0.369TrpGln: 0.369 ± 0.348
1.107TrpArg: 1.107 ± 0.617
0.0TrpSer: 0.0 ± 0.0
1.845TrpThr: 1.845 ± 0.995
1.476TrpVal: 1.476 ± 0.843
0.0TrpTrp: 0.0 ± 0.0
0.369TrpTyr: 0.369 ± 0.388
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.69TyrAla: 3.69 ± 1.131
0.0TyrCys: 0.0 ± 0.0
2.214TyrAsp: 2.214 ± 0.822
4.428TyrGlu: 4.428 ± 1.173
1.845TyrPhe: 1.845 ± 0.873
2.214TyrGly: 2.214 ± 0.799
1.107TyrHis: 1.107 ± 0.862
0.369TyrIle: 0.369 ± 0.292
1.476TyrLys: 1.476 ± 0.389
2.214TyrLeu: 2.214 ± 1.074
0.369TyrMet: 0.369 ± 0.292
1.476TyrAsn: 1.476 ± 0.803
1.476TyrPro: 1.476 ± 0.932
1.107TyrGln: 1.107 ± 0.685
2.214TyrArg: 2.214 ± 0.461
2.214TyrSer: 2.214 ± 0.826
2.214TyrThr: 2.214 ± 1.492
4.059TyrVal: 4.059 ± 0.745
0.0TyrTrp: 0.0 ± 0.0
2.583TyrTyr: 2.583 ± 0.9
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 13 proteins (2711 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski