Amino acid dipepetide frequency for Pseudovibrio axinellae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.198AlaAla: 11.198 ± 0.105	1.054AlaCys: 1.054 ± 0.028	5.313AlaAsp: 5.313 ± 0.066	6.269AlaGlu: 6.269 ± 0.072	4.118AlaPhe: 4.118 ± 0.057	8.131AlaGly: 8.131 ± 0.087	2.027AlaHis: 2.027 ± 0.037	5.845AlaIle: 5.845 ± 0.072	4.708AlaLys: 4.708 ± 0.066	11.4AlaLeu: 11.4 ± 0.088	2.898AlaMet: 2.898 ± 0.05	3.183AlaAsn: 3.183 ± 0.044	4.14AlaPro: 4.14 ± 0.056	4.127AlaGln: 4.127 ± 0.063	5.421AlaArg: 5.421 ± 0.068	6.137AlaSer: 6.137 ± 0.073	4.958AlaThr: 4.958 ± 0.071	7.154AlaVal: 7.154 ± 0.07	1.079AlaTrp: 1.079 ± 0.029	2.546AlaTyr: 2.546 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	1.011CysAla: 1.011 ± 0.025	0.154CysCys: 0.154 ± 0.013	0.605CysAsp: 0.605 ± 0.023	0.632CysGlu: 0.632 ± 0.022	0.44CysPhe: 0.44 ± 0.016	0.986CysGly: 0.986 ± 0.031	0.276CysHis: 0.276 ± 0.015	0.508CysIle: 0.508 ± 0.019	0.368CysLys: 0.368 ± 0.016	0.909CysLeu: 0.909 ± 0.025	0.231CysMet: 0.231 ± 0.013	0.319CysAsn: 0.319 ± 0.016	0.443CysPro: 0.443 ± 0.019	0.345CysGln: 0.345 ± 0.017	0.523CysArg: 0.523 ± 0.019	0.653CysSer: 0.653 ± 0.025	0.504CysThr: 0.504 ± 0.021	0.758CysVal: 0.758 ± 0.021	0.121CysTrp: 0.121 ± 0.01	0.272CysTyr: 0.272 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	5.313AspAla: 5.313 ± 0.063	0.544AspCys: 0.544 ± 0.023	2.831AspAsp: 2.831 ± 0.055	3.861AspGlu: 3.861 ± 0.063	2.294AspPhe: 2.294 ± 0.043	4.533AspGly: 4.533 ± 0.072	1.241AspHis: 1.241 ± 0.028	3.229AspIle: 3.229 ± 0.05	2.329AspLys: 2.329 ± 0.045	5.962AspLeu: 5.962 ± 0.059	1.428AspMet: 1.428 ± 0.032	1.634AspAsn: 1.634 ± 0.033	2.803AspPro: 2.803 ± 0.055	1.963AspGln: 1.963 ± 0.035	3.103AspArg: 3.103 ± 0.048	2.348AspSer: 2.348 ± 0.042	2.734AspThr: 2.734 ± 0.052	3.974AspVal: 3.974 ± 0.056	0.91AspTrp: 0.91 ± 0.03	1.595AspTyr: 1.595 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	6.824GluAla: 6.824 ± 0.079	0.495GluCys: 0.495 ± 0.02	3.453GluAsp: 3.453 ± 0.052	4.414GluGlu: 4.414 ± 0.067	2.24GluPhe: 2.24 ± 0.038	4.43GluGly: 4.43 ± 0.059	1.435GluHis: 1.435 ± 0.037	3.81GluIle: 3.81 ± 0.063	3.311GluLys: 3.311 ± 0.054	6.567GluLeu: 6.567 ± 0.069	1.665GluMet: 1.665 ± 0.032	2.461GluAsn: 2.461 ± 0.043	2.495GluPro: 2.495 ± 0.046	2.77GluGln: 2.77 ± 0.05	4.161GluArg: 4.161 ± 0.059	2.724GluSer: 2.724 ± 0.043	3.777GluThr: 3.777 ± 0.052	4.296GluVal: 4.296 ± 0.057	0.72GluTrp: 0.72 ± 0.022	1.345GluTyr: 1.345 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.254PheAla: 4.254 ± 0.056	0.511PheCys: 0.511 ± 0.019	2.615PheAsp: 2.615 ± 0.048	2.634PheGlu: 2.634 ± 0.048	1.782PhePhe: 1.782 ± 0.04	3.566PheGly: 3.566 ± 0.058	0.815PheHis: 0.815 ± 0.025	2.242PheIle: 2.242 ± 0.046	1.665PheLys: 1.665 ± 0.03	3.892PheLeu: 3.892 ± 0.059	1.016PheMet: 1.016 ± 0.027	1.358PheAsn: 1.358 ± 0.03	1.582PhePro: 1.582 ± 0.038	1.322PheGln: 1.322 ± 0.028	1.854PheArg: 1.854 ± 0.035	3.002PheSer: 3.002 ± 0.052	2.204PheThr: 2.204 ± 0.036	2.952PheVal: 2.952 ± 0.05	0.642PheTrp: 0.642 ± 0.019	1.162PheTyr: 1.162 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	7.369GlyAla: 7.369 ± 0.088	0.852GlyCys: 0.852 ± 0.026	4.065GlyAsp: 4.065 ± 0.069	4.793GlyGlu: 4.793 ± 0.066	3.606GlyPhe: 3.606 ± 0.058	6.145GlyGly: 6.145 ± 0.087	1.697GlyHis: 1.697 ± 0.043	4.569GlyIle: 4.569 ± 0.069	3.826GlyLys: 3.826 ± 0.059	8.09GlyLeu: 8.09 ± 0.084	2.158GlyMet: 2.158 ± 0.04	2.477GlyAsn: 2.477 ± 0.054	2.759GlyPro: 2.759 ± 0.043	2.885GlyGln: 2.885 ± 0.052	4.344GlyArg: 4.344 ± 0.058	4.785GlySer: 4.785 ± 0.067	4.301GlyThr: 4.301 ± 0.069	5.856GlyVal: 5.856 ± 0.066	1.147GlyTrp: 1.147 ± 0.031	2.465GlyTyr: 2.465 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.852HisAla: 1.852 ± 0.038	0.26HisCys: 0.26 ± 0.014	1.151HisAsp: 1.151 ± 0.027	1.191HisGlu: 1.191 ± 0.028	0.934HisPhe: 0.934 ± 0.026	1.739HisGly: 1.739 ± 0.039	0.579HisHis: 0.579 ± 0.025	1.185HisIle: 1.185 ± 0.029	0.835HisLys: 0.835 ± 0.024	2.172HisLeu: 2.172 ± 0.039	0.582HisMet: 0.582 ± 0.02	0.695HisAsn: 0.695 ± 0.023	1.183HisPro: 1.183 ± 0.033	0.747HisGln: 0.747 ± 0.024	1.133HisArg: 1.133 ± 0.027	1.312HisSer: 1.312 ± 0.031	1.016HisThr: 1.016 ± 0.028	1.404HisVal: 1.404 ± 0.034	0.328HisTrp: 0.328 ± 0.016	0.635HisTyr: 0.635 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.537IleAla: 6.537 ± 0.078	0.709IleCys: 0.709 ± 0.024	3.386IleAsp: 3.386 ± 0.048	3.964IleGlu: 3.964 ± 0.051	2.163IlePhe: 2.163 ± 0.042	4.867IleGly: 4.867 ± 0.071	0.979IleHis: 0.979 ± 0.027	2.955IleIle: 2.955 ± 0.056	2.353IleLys: 2.353 ± 0.045	5.162IleLeu: 5.162 ± 0.075	1.215IleMet: 1.215 ± 0.032	1.936IleAsn: 1.936 ± 0.036	2.565IlePro: 2.565 ± 0.041	1.658IleGln: 1.658 ± 0.038	2.9IleArg: 2.9 ± 0.044	4.242IleSer: 4.242 ± 0.063	3.327IleThr: 3.327 ± 0.047	3.975IleVal: 3.975 ± 0.066	0.714IleTrp: 0.714 ± 0.024	1.437IleTyr: 1.437 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.925LysAla: 4.925 ± 0.065	0.308LysCys: 0.308 ± 0.014	2.59LysAsp: 2.59 ± 0.047	2.877LysGlu: 2.877 ± 0.051	1.409LysPhe: 1.409 ± 0.034	3.293LysGly: 3.293 ± 0.051	0.994LysHis: 0.994 ± 0.028	2.584LysIle: 2.584 ± 0.044	2.241LysLys: 2.241 ± 0.051	4.621LysLeu: 4.621 ± 0.053	1.11LysMet: 1.11 ± 0.03	1.624LysAsn: 1.624 ± 0.037	2.373LysPro: 2.373 ± 0.043	1.845LysGln: 1.845 ± 0.037	2.826LysArg: 2.826 ± 0.048	2.786LysSer: 2.786 ± 0.047	2.718LysThr: 2.718 ± 0.037	3.233LysVal: 3.233 ± 0.05	0.568LysTrp: 0.568 ± 0.022	0.972LysTyr: 0.972 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	10.523LeuAla: 10.523 ± 0.096	1.108LeuCys: 1.108 ± 0.029	5.498LeuAsp: 5.498 ± 0.072	6.463LeuGlu: 6.463 ± 0.075	4.0LeuPhe: 4.0 ± 0.062	7.828LeuGly: 7.828 ± 0.083	2.001LeuHis: 2.001 ± 0.042	5.732LeuIle: 5.732 ± 0.081	5.047LeuLys: 5.047 ± 0.057	9.601LeuLeu: 9.601 ± 0.106	2.522LeuMet: 2.522 ± 0.049	3.618LeuAsn: 3.618 ± 0.057	5.094LeuPro: 5.094 ± 0.069	3.509LeuGln: 3.509 ± 0.053	5.5LeuArg: 5.5 ± 0.072	7.926LeuSer: 7.926 ± 0.079	5.536LeuThr: 5.536 ± 0.072	7.032LeuVal: 7.032 ± 0.08	1.104LeuTrp: 1.104 ± 0.032	2.319LeuTyr: 2.319 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.701MetAla: 2.701 ± 0.046	0.228MetCys: 0.228 ± 0.014	1.284MetAsp: 1.284 ± 0.029	1.376MetGlu: 1.376 ± 0.029	0.874MetPhe: 0.874 ± 0.024	1.965MetGly: 1.965 ± 0.037	0.481MetHis: 0.481 ± 0.018	1.419MetIle: 1.419 ± 0.036	1.356MetLys: 1.356 ± 0.032	2.527MetLeu: 2.527 ± 0.041	0.7MetMet: 0.7 ± 0.024	0.914MetAsn: 0.914 ± 0.025	1.367MetPro: 1.367 ± 0.03	0.989MetGln: 0.989 ± 0.027	1.604MetArg: 1.604 ± 0.036	1.958MetSer: 1.958 ± 0.037	1.711MetThr: 1.711 ± 0.034	1.787MetVal: 1.787 ± 0.037	0.227MetTrp: 0.227 ± 0.013	0.399MetTyr: 0.399 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.507AsnAla: 3.507 ± 0.047	0.321AsnCys: 0.321 ± 0.016	1.666AsnAsp: 1.666 ± 0.035	1.888AsnGlu: 1.888 ± 0.037	1.338AsnPhe: 1.338 ± 0.032	2.786AsnGly: 2.786 ± 0.052	0.653AsnHis: 0.653 ± 0.021	1.9AsnIle: 1.9 ± 0.037	1.442AsnLys: 1.442 ± 0.036	3.284AsnLeu: 3.284 ± 0.054	0.86AsnMet: 0.86 ± 0.024	1.155AsnAsn: 1.155 ± 0.033	1.994AsnPro: 1.994 ± 0.038	1.18AsnGln: 1.18 ± 0.028	1.836AsnArg: 1.836 ± 0.034	2.08AsnSer: 2.08 ± 0.037	1.97AsnThr: 1.97 ± 0.042	2.285AsnVal: 2.285 ± 0.042	0.565AsnTrp: 0.565 ± 0.019	0.971AsnTyr: 0.971 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	4.305ProAla: 4.305 ± 0.057	0.337ProCys: 0.337 ± 0.016	2.919ProAsp: 2.919 ± 0.047	3.635ProGlu: 3.635 ± 0.047	1.994ProPhe: 1.994 ± 0.034	3.096ProGly: 3.096 ± 0.049	1.05ProHis: 1.05 ± 0.028	2.452ProIle: 2.452 ± 0.045	2.141ProLys: 2.141 ± 0.04	4.318ProLeu: 4.318 ± 0.056	1.104ProMet: 1.104 ± 0.028	1.592ProAsn: 1.592 ± 0.038	1.704ProPro: 1.704 ± 0.037	1.719ProGln: 1.719 ± 0.041	2.042ProArg: 2.042 ± 0.041	2.899ProSer: 2.899 ± 0.053	2.371ProThr: 2.371 ± 0.043	3.708ProVal: 3.708 ± 0.055	0.536ProTrp: 0.536 ± 0.019	1.21ProTyr: 1.21 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	3.876GlnAla: 3.876 ± 0.06	0.258GlnCys: 0.258 ± 0.011	1.911GlnAsp: 1.911 ± 0.042	2.299GlnGlu: 2.299 ± 0.048	1.403GlnPhe: 1.403 ± 0.03	2.496GlnGly: 2.496 ± 0.044	0.811GlnHis: 0.811 ± 0.024	2.346GlnIle: 2.346 ± 0.042	1.798GlnLys: 1.798 ± 0.038	3.656GlnLeu: 3.656 ± 0.056	1.098GlnMet: 1.098 ± 0.032	1.399GlnAsn: 1.399 ± 0.031	1.532GlnPro: 1.532 ± 0.036	1.561GlnGln: 1.561 ± 0.038	2.286GlnArg: 2.286 ± 0.037	2.373GlnSer: 2.373 ± 0.042	2.055GlnThr: 2.055 ± 0.041	2.664GlnVal: 2.664 ± 0.045	0.419GlnTrp: 0.419 ± 0.016	0.784GlnTyr: 0.784 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	5.151ArgAla: 5.151 ± 0.061	0.477ArgCys: 0.477 ± 0.019	2.886ArgAsp: 2.886 ± 0.059	3.448ArgGlu: 3.448 ± 0.048	2.54ArgPhe: 2.54 ± 0.049	3.529ArgGly: 3.529 ± 0.052	1.215ArgHis: 1.215 ± 0.031	3.375ArgIle: 3.375 ± 0.053	2.786ArgLys: 2.786 ± 0.05	5.963ArgLeu: 5.963 ± 0.079	1.466ArgMet: 1.466 ± 0.028	1.843ArgAsn: 1.843 ± 0.035	2.405ArgPro: 2.405 ± 0.044	2.115ArgGln: 2.115 ± 0.04	3.508ArgArg: 3.508 ± 0.058	3.489ArgSer: 3.489 ± 0.056	2.717ArgThr: 2.717 ± 0.045	3.894ArgVal: 3.894 ± 0.049	0.713ArgTrp: 0.713 ± 0.024	1.531ArgTyr: 1.531 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	6.276SerAla: 6.276 ± 0.066	0.638SerCys: 0.638 ± 0.026	3.518SerAsp: 3.518 ± 0.057	3.947SerGlu: 3.947 ± 0.053	2.955SerPhe: 2.955 ± 0.053	5.694SerGly: 5.694 ± 0.06	1.264SerHis: 1.264 ± 0.031	3.646SerIle: 3.646 ± 0.05	2.905SerLys: 2.905 ± 0.049	6.379SerLeu: 6.379 ± 0.077	1.68SerMet: 1.68 ± 0.034	2.132SerAsn: 2.132 ± 0.04	2.689SerPro: 2.689 ± 0.047	2.472SerGln: 2.472 ± 0.053	3.211SerArg: 3.211 ± 0.06	4.321SerSer: 4.321 ± 0.064	3.235SerThr: 3.235 ± 0.054	4.654SerVal: 4.654 ± 0.061	0.89SerTrp: 0.89 ± 0.025	1.714SerTyr: 1.714 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.331ThrAla: 5.331 ± 0.059	0.562ThrCys: 0.562 ± 0.025	2.792ThrAsp: 2.792 ± 0.051	2.797ThrGlu: 2.797 ± 0.052	2.148ThrPhe: 2.148 ± 0.039	4.731ThrGly: 4.731 ± 0.065	1.167ThrHis: 1.167 ± 0.027	3.06ThrIle: 3.06 ± 0.053	2.204ThrLys: 2.204 ± 0.034	5.837ThrLeu: 5.837 ± 0.061	1.213ThrMet: 1.213 ± 0.031	1.785ThrAsn: 1.785 ± 0.039	3.054ThrPro: 3.054 ± 0.049	1.996ThrGln: 1.996 ± 0.037	2.743ThrArg: 2.743 ± 0.046	3.572ThrSer: 3.572 ± 0.047	2.971ThrThr: 2.971 ± 0.056	3.978ThrVal: 3.978 ± 0.068	0.62ThrTrp: 0.62 ± 0.019	1.488ThrTyr: 1.488 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	7.247ValAla: 7.247 ± 0.075	0.777ValCys: 0.777 ± 0.027	3.992ValAsp: 3.992 ± 0.056	4.68ValGlu: 4.68 ± 0.067	3.176ValPhe: 3.176 ± 0.052	5.281ValGly: 5.281 ± 0.067	1.421ValHis: 1.421 ± 0.031	4.198ValIle: 4.198 ± 0.053	2.957ValLys: 2.957 ± 0.045	7.427ValLeu: 7.427 ± 0.079	1.977ValMet: 1.977 ± 0.043	2.251ValAsn: 2.251 ± 0.04	3.27ValPro: 3.27 ± 0.048	2.229ValGln: 2.229 ± 0.042	3.69ValArg: 3.69 ± 0.049	5.133ValSer: 5.133 ± 0.065	4.018ValThr: 4.018 ± 0.061	5.557ValVal: 5.557 ± 0.088	0.815ValTrp: 0.815 ± 0.024	1.651ValTyr: 1.651 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.103TrpAla: 1.103 ± 0.029	0.134TrpCys: 0.134 ± 0.009	0.626TrpAsp: 0.626 ± 0.024	0.657TrpGlu: 0.657 ± 0.024	0.544TrpPhe: 0.544 ± 0.021	0.952TrpGly: 0.952 ± 0.026	0.301TrpHis: 0.301 ± 0.016	0.701TrpIle: 0.701 ± 0.025	0.576TrpLys: 0.576 ± 0.021	1.44TrpLeu: 1.44 ± 0.032	0.353TrpMet: 0.353 ± 0.015	0.466TrpAsn: 0.466 ± 0.017	0.556TrpPro: 0.556 ± 0.019	0.634TrpGln: 0.634 ± 0.02	0.821TrpArg: 0.821 ± 0.025	0.873TrpSer: 0.873 ± 0.023	0.638TrpThr: 0.638 ± 0.021	0.898TrpVal: 0.898 ± 0.024	0.211TrpTrp: 0.211 ± 0.012	0.289TrpTyr: 0.289 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.403TyrAla: 2.403 ± 0.04	0.329TyrCys: 0.329 ± 0.013	1.529TyrAsp: 1.529 ± 0.034	1.566TyrGlu: 1.566 ± 0.035	1.113TyrPhe: 1.113 ± 0.03	2.145TyrGly: 2.145 ± 0.038	0.526TyrHis: 0.526 ± 0.021	1.29TyrIle: 1.29 ± 0.029	1.052TyrLys: 1.052 ± 0.029	2.751TyrLeu: 2.751 ± 0.052	0.591TyrMet: 0.591 ± 0.019	0.837TyrAsn: 0.837 ± 0.027	1.128TyrPro: 1.128 ± 0.032	0.957TyrGln: 0.957 ± 0.025	1.543TyrArg: 1.543 ± 0.03	1.606TyrSer: 1.606 ± 0.034	1.291TyrThr: 1.291 ± 0.033	1.685TyrVal: 1.685 ± 0.036	0.442TyrTrp: 0.442 ± 0.018	0.793TyrTyr: 0.793 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4634 proteins (1443537 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---