Amino acid dipepetide frequency for Beihai picorna-like virus 27

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.105AlaAla: 6.105 ± 0.947
1.526AlaCys: 1.526 ± 0.91
4.96AlaAsp: 4.96 ± 1.083
5.723AlaGlu: 5.723 ± 1.392
4.578AlaPhe: 4.578 ± 0.036
6.105AlaGly: 6.105 ± 0.4
2.289AlaHis: 2.289 ± 1.365
3.815AlaIle: 3.815 ± 0.419
4.197AlaLys: 4.197 ± 2.503
4.96AlaLeu: 4.96 ± 0.937
1.908AlaMet: 1.908 ± 0.464
2.671AlaAsn: 2.671 ± 0.246
3.434AlaPro: 3.434 ± 0.646
1.526AlaGln: 1.526 ± 0.237
3.815AlaArg: 3.815 ± 0.255
4.578AlaSer: 4.578 ± 0.637
4.96AlaThr: 4.96 ± 2.43
3.434AlaVal: 3.434 ± 0.701
1.526AlaTrp: 1.526 ± 0.237
3.434AlaTyr: 3.434 ± 0.701
0.0AlaXaa: 0.0 ± 0.0
Cys
1.145CysAla: 1.145 ± 0.009
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.763CysGlu: 0.763 ± 0.455
0.763CysPhe: 0.763 ± 0.455
0.763CysGly: 0.763 ± 0.455
0.382CysHis: 0.382 ± 0.446
0.0CysIle: 0.0 ± 0.0
0.382CysLys: 0.382 ± 0.228
1.526CysLeu: 1.526 ± 0.91
0.382CysMet: 0.382 ± 0.228
1.908CysAsn: 1.908 ± 0.209
0.763CysPro: 0.763 ± 0.455
0.382CysGln: 0.382 ± 0.228
0.382CysArg: 0.382 ± 0.228
2.289CysSer: 2.289 ± 0.018
2.289CysThr: 2.289 ± 0.692
1.908CysVal: 1.908 ± 0.209
0.0CysTrp: 0.0 ± 0.0
0.382CysTyr: 0.382 ± 0.446
0.0CysXaa: 0.0 ± 0.0
Asp
5.341AspAla: 5.341 ± 0.182
0.382AspCys: 0.382 ± 0.228
4.578AspAsp: 4.578 ± 0.637
4.96AspGlu: 4.96 ± 0.409
4.197AspPhe: 4.197 ± 0.191
4.197AspGly: 4.197 ± 0.191
1.526AspHis: 1.526 ± 0.237
3.815AspIle: 3.815 ± 1.092
3.815AspLys: 3.815 ± 0.419
5.341AspLeu: 5.341 ± 0.492
0.763AspMet: 0.763 ± 0.892
1.908AspAsn: 1.908 ± 0.883
2.289AspPro: 2.289 ± 0.655
1.526AspGln: 1.526 ± 0.237
0.763AspArg: 0.763 ± 0.218
3.434AspSer: 3.434 ± 0.027
2.671AspThr: 2.671 ± 1.101
4.578AspVal: 4.578 ± 0.036
0.382AspTrp: 0.382 ± 0.228
2.671AspTyr: 2.671 ± 0.246
0.0AspXaa: 0.0 ± 0.0
Glu
4.578GluAla: 4.578 ± 0.71
0.382GluCys: 0.382 ± 0.228
4.197GluAsp: 4.197 ± 0.191
3.052GluGlu: 3.052 ± 0.473
2.671GluPhe: 2.671 ± 0.919
4.197GluGly: 4.197 ± 0.864
1.145GluHis: 1.145 ± 0.683
3.815GluIle: 3.815 ± 0.928
3.052GluLys: 3.052 ± 1.82
5.723GluLeu: 5.723 ± 0.628
1.908GluMet: 1.908 ± 1.024
1.908GluAsn: 1.908 ± 1.138
2.289GluPro: 2.289 ± 1.329
1.908GluGln: 1.908 ± 1.138
4.96GluArg: 4.96 ± 1.611
7.631GluSer: 7.631 ± 0.837
3.052GluThr: 3.052 ± 0.473
4.197GluVal: 4.197 ± 0.864
1.145GluTrp: 1.145 ± 0.009
5.723GluTyr: 5.723 ± 2.066
0.0GluXaa: 0.0 ± 0.0
Phe
3.815PheAla: 3.815 ± 0.928
0.382PheCys: 0.382 ± 0.446
3.052PheAsp: 3.052 ± 0.2
4.197PheGlu: 4.197 ± 0.482
2.671PhePhe: 2.671 ± 1.593
3.815PheGly: 3.815 ± 0.419
1.145PheHis: 1.145 ± 0.009
3.815PheIle: 3.815 ± 1.602
4.578PheLys: 4.578 ± 1.383
4.197PheLeu: 4.197 ± 1.829
1.526PheMet: 1.526 ± 0.237
3.052PheAsn: 3.052 ± 0.874
2.289PhePro: 2.289 ± 0.655
2.671PheGln: 2.671 ± 1.101
1.145PheArg: 1.145 ± 0.009
3.434PheSer: 3.434 ± 0.701
2.289PheThr: 2.289 ± 0.692
1.908PheVal: 1.908 ± 0.883
1.145PheTrp: 1.145 ± 0.683
1.526PheTyr: 1.526 ± 0.437
0.0PheXaa: 0.0 ± 0.0
Gly
3.434GlyAla: 3.434 ± 0.027
0.382GlyCys: 0.382 ± 0.228
3.815GlyAsp: 3.815 ± 1.092
3.052GlyGlu: 3.052 ± 0.874
2.671GlyPhe: 2.671 ± 0.246
3.052GlyGly: 3.052 ± 1.547
0.763GlyHis: 0.763 ± 0.455
5.341GlyIle: 5.341 ± 0.492
5.723GlyLys: 5.723 ± 0.046
5.341GlyLeu: 5.341 ± 0.492
1.145GlyMet: 1.145 ± 0.241
1.526GlyAsn: 1.526 ± 0.237
2.289GlyPro: 2.289 ± 1.329
1.908GlyGln: 1.908 ± 0.883
2.289GlyArg: 2.289 ± 0.692
6.105GlySer: 6.105 ± 0.947
3.434GlyThr: 3.434 ± 1.319
3.815GlyVal: 3.815 ± 0.419
0.0GlyTrp: 0.0 ± 0.0
2.289GlyTyr: 2.289 ± 0.018
0.0GlyXaa: 0.0 ± 0.0
His
1.908HisAla: 1.908 ± 0.464
0.763HisCys: 0.763 ± 0.455
0.0HisAsp: 0.0 ± 0.0
2.289HisGlu: 2.289 ± 1.365
1.145HisPhe: 1.145 ± 0.009
1.145HisGly: 1.145 ± 0.683
0.382HisHis: 0.382 ± 0.228
2.671HisIle: 2.671 ± 0.428
0.763HisLys: 0.763 ± 0.218
0.763HisLeu: 0.763 ± 0.455
0.382HisMet: 0.382 ± 0.228
0.0HisAsn: 0.0 ± 0.0
1.526HisPro: 1.526 ± 0.237
0.382HisGln: 0.382 ± 0.228
1.526HisArg: 1.526 ± 0.237
0.763HisSer: 0.763 ± 0.218
0.763HisThr: 0.763 ± 0.218
0.763HisVal: 0.763 ± 0.455
0.0HisTrp: 0.0 ± 0.0
0.763HisTyr: 0.763 ± 0.218
0.0HisXaa: 0.0 ± 0.0
Ile
4.578IleAla: 4.578 ± 0.637
1.145IleCys: 1.145 ± 0.683
4.578IleAsp: 4.578 ± 0.036
3.434IleGlu: 3.434 ± 0.701
2.671IlePhe: 2.671 ± 0.428
0.763IleGly: 0.763 ± 0.218
1.526IleHis: 1.526 ± 0.237
3.434IleIle: 3.434 ± 0.646
5.341IleLys: 5.341 ± 1.165
3.815IleLeu: 3.815 ± 2.275
1.526IleMet: 1.526 ± 0.91
4.96IleAsn: 4.96 ± 0.264
2.289IlePro: 2.289 ± 0.018
1.908IleGln: 1.908 ± 0.883
2.289IleArg: 2.289 ± 0.692
3.815IleSer: 3.815 ± 2.439
4.578IleThr: 4.578 ± 2.657
4.96IleVal: 4.96 ± 1.756
0.382IleTrp: 0.382 ± 0.228
2.289IleTyr: 2.289 ± 0.018
0.0IleXaa: 0.0 ± 0.0
Lys
6.486LysAla: 6.486 ± 1.847
0.382LysCys: 0.382 ± 0.228
1.908LysAsp: 1.908 ± 0.464
4.96LysGlu: 4.96 ± 0.937
2.671LysPhe: 2.671 ± 0.246
4.578LysGly: 4.578 ± 0.71
0.763LysHis: 0.763 ± 0.455
4.197LysIle: 4.197 ± 1.829
3.434LysLys: 3.434 ± 1.374
6.868LysLeu: 6.868 ± 1.292
1.526LysMet: 1.526 ± 0.237
2.671LysAsn: 2.671 ± 0.919
3.052LysPro: 3.052 ± 0.2
2.289LysGln: 2.289 ± 0.018
2.671LysArg: 2.671 ± 0.246
6.486LysSer: 6.486 ± 2.521
3.815LysThr: 3.815 ± 2.275
5.341LysVal: 5.341 ± 0.492
0.763LysTrp: 0.763 ± 0.455
2.289LysTyr: 2.289 ± 0.655
0.0LysXaa: 0.0 ± 0.0
Leu
6.868LeuAla: 6.868 ± 2.075
2.289LeuCys: 2.289 ± 0.692
8.012LeuAsp: 8.012 ± 0.737
4.96LeuGlu: 4.96 ± 0.409
4.96LeuPhe: 4.96 ± 1.611
1.526LeuGly: 1.526 ± 0.237
2.289LeuHis: 2.289 ± 0.018
4.197LeuIle: 4.197 ± 0.482
5.341LeuLys: 5.341 ± 1.165
2.671LeuLeu: 2.671 ± 0.919
2.671LeuMet: 2.671 ± 0.246
3.815LeuAsn: 3.815 ± 1.765
3.815LeuPro: 3.815 ± 0.419
3.052LeuGln: 3.052 ± 0.2
4.578LeuArg: 4.578 ± 1.31
6.868LeuSer: 6.868 ± 1.292
6.868LeuThr: 6.868 ± 0.619
3.052LeuVal: 3.052 ± 1.147
0.0LeuTrp: 0.0 ± 0.0
0.382LeuTyr: 0.382 ± 0.228
0.0LeuXaa: 0.0 ± 0.0
Met
2.671MetAla: 2.671 ± 1.101
0.382MetCys: 0.382 ± 0.446
1.908MetAsp: 1.908 ± 0.464
1.145MetGlu: 1.145 ± 0.009
1.145MetPhe: 1.145 ± 0.009
1.145MetGly: 1.145 ± 0.664
0.382MetHis: 0.382 ± 0.446
0.382MetIle: 0.382 ± 0.228
2.289MetLys: 2.289 ± 0.018
3.052MetLeu: 3.052 ± 0.473
0.763MetMet: 0.763 ± 0.455
0.763MetAsn: 0.763 ± 0.455
0.382MetPro: 0.382 ± 0.228
0.763MetGln: 0.763 ± 0.218
1.526MetArg: 1.526 ± 0.91
1.526MetSer: 1.526 ± 0.237
1.908MetThr: 1.908 ± 0.464
1.145MetVal: 1.145 ± 0.683
0.382MetTrp: 0.382 ± 0.228
0.763MetTyr: 0.763 ± 0.218
0.0MetXaa: 0.0 ± 0.0
Asn
1.145AsnAla: 1.145 ± 0.009
1.526AsnCys: 1.526 ± 0.437
1.526AsnAsp: 1.526 ± 0.437
1.908AsnGlu: 1.908 ± 0.464
3.815AsnPhe: 3.815 ± 1.602
3.815AsnGly: 3.815 ± 1.092
0.382AsnHis: 0.382 ± 0.228
3.052AsnIle: 3.052 ± 0.874
2.289AsnLys: 2.289 ± 0.018
4.578AsnLeu: 4.578 ± 1.31
1.526AsnMet: 1.526 ± 0.237
0.382AsnAsn: 0.382 ± 0.228
1.908AsnPro: 1.908 ± 0.464
1.908AsnGln: 1.908 ± 0.883
1.908AsnArg: 1.908 ± 0.209
3.052AsnSer: 3.052 ± 0.874
2.671AsnThr: 2.671 ± 0.428
2.671AsnVal: 2.671 ± 0.246
1.526AsnTrp: 1.526 ± 0.437
1.908AsnTyr: 1.908 ± 0.883
0.0AsnXaa: 0.0 ± 0.0
Pro
3.434ProAla: 3.434 ± 0.701
0.763ProCys: 0.763 ± 0.455
3.052ProAsp: 3.052 ± 1.547
3.052ProGlu: 3.052 ± 0.473
3.434ProPhe: 3.434 ± 0.646
1.526ProGly: 1.526 ± 0.237
0.763ProHis: 0.763 ± 0.455
2.289ProIle: 2.289 ± 1.329
2.671ProLys: 2.671 ± 0.428
5.723ProLeu: 5.723 ± 1.392
0.382ProMet: 0.382 ± 0.446
1.526ProAsn: 1.526 ± 0.437
1.145ProPro: 1.145 ± 0.009
1.145ProGln: 1.145 ± 0.009
1.145ProArg: 1.145 ± 0.683
1.526ProSer: 1.526 ± 0.237
3.052ProThr: 3.052 ± 1.547
4.96ProVal: 4.96 ± 1.756
0.763ProTrp: 0.763 ± 0.892
3.052ProTyr: 3.052 ± 0.874
0.0ProXaa: 0.0 ± 0.0
Gln
1.908GlnAla: 1.908 ± 1.138
0.763GlnCys: 0.763 ± 0.455
2.289GlnAsp: 2.289 ± 0.655
2.671GlnGlu: 2.671 ± 0.246
1.145GlnPhe: 1.145 ± 0.009
1.526GlnGly: 1.526 ± 0.237
0.382GlnHis: 0.382 ± 0.228
4.197GlnIle: 4.197 ± 2.211
1.908GlnLys: 1.908 ± 0.464
4.197GlnLeu: 4.197 ± 0.191
0.763GlnMet: 0.763 ± 0.455
2.671GlnAsn: 2.671 ± 1.774
0.763GlnPro: 0.763 ± 0.218
0.763GlnGln: 0.763 ± 0.455
0.763GlnArg: 0.763 ± 0.218
2.671GlnSer: 2.671 ± 0.428
1.145GlnThr: 1.145 ± 0.664
1.908GlnVal: 1.908 ± 1.138
0.763GlnTrp: 0.763 ± 0.455
1.145GlnTyr: 1.145 ± 0.664
0.0GlnXaa: 0.0 ± 0.0
Arg
3.052ArgAla: 3.052 ± 0.473
0.763ArgCys: 0.763 ± 0.455
3.052ArgAsp: 3.052 ± 0.2
4.197ArgGlu: 4.197 ± 1.829
2.671ArgPhe: 2.671 ± 0.246
4.96ArgGly: 4.96 ± 1.083
0.382ArgHis: 0.382 ± 0.228
1.145ArgIle: 1.145 ± 0.664
5.341ArgLys: 5.341 ± 2.512
3.052ArgLeu: 3.052 ± 0.874
0.763ArgMet: 0.763 ± 0.218
2.289ArgAsn: 2.289 ± 0.655
4.197ArgPro: 4.197 ± 0.191
1.526ArgGln: 1.526 ± 0.91
2.671ArgArg: 2.671 ± 0.246
1.908ArgSer: 1.908 ± 0.209
1.908ArgThr: 1.908 ± 0.209
1.526ArgVal: 1.526 ± 0.91
0.382ArgTrp: 0.382 ± 0.446
0.382ArgTyr: 0.382 ± 0.446
0.0ArgXaa: 0.0 ± 0.0
Ser
5.341SerAla: 5.341 ± 1.529
2.671SerCys: 2.671 ± 0.428
5.341SerAsp: 5.341 ± 0.855
7.249SerGlu: 7.249 ± 0.282
3.052SerPhe: 3.052 ± 0.473
4.96SerGly: 4.96 ± 0.264
0.763SerHis: 0.763 ± 0.218
5.723SerIle: 5.723 ± 0.046
7.631SerLys: 7.631 ± 0.51
3.815SerLeu: 3.815 ± 1.092
1.526SerMet: 1.526 ± 0.437
2.289SerAsn: 2.289 ± 0.655
3.815SerPro: 3.815 ± 0.928
4.197SerGln: 4.197 ± 0.482
2.671SerArg: 2.671 ± 0.428
4.578SerSer: 4.578 ± 1.31
3.434SerThr: 3.434 ± 0.027
4.197SerVal: 4.197 ± 0.864
1.908SerTrp: 1.908 ± 1.556
1.145SerTyr: 1.145 ± 0.664
0.0SerXaa: 0.0 ± 0.0
Thr
2.289ThrAla: 2.289 ± 0.655
1.145ThrCys: 1.145 ± 0.664
2.671ThrAsp: 2.671 ± 0.246
3.052ThrGlu: 3.052 ± 0.874
2.671ThrPhe: 2.671 ± 0.246
3.052ThrGly: 3.052 ± 0.874
0.763ThrHis: 0.763 ± 0.892
3.052ThrIle: 3.052 ± 0.2
2.671ThrLys: 2.671 ± 0.246
4.96ThrLeu: 4.96 ± 0.264
1.526ThrMet: 1.526 ± 0.91
3.434ThrAsn: 3.434 ± 0.027
4.578ThrPro: 4.578 ± 1.984
2.671ThrGln: 2.671 ± 2.448
3.815ThrArg: 3.815 ± 0.419
4.197ThrSer: 4.197 ± 1.538
3.815ThrThr: 3.815 ± 0.419
6.486ThrVal: 6.486 ± 0.846
0.0ThrTrp: 0.0 ± 0.0
4.197ThrTyr: 4.197 ± 0.191
0.0ThrXaa: 0.0 ± 0.0
Val
6.868ValAla: 6.868 ± 0.619
0.0ValCys: 0.0 ± 0.0
3.052ValAsp: 3.052 ± 0.2
4.96ValGlu: 4.96 ± 0.937
3.052ValPhe: 3.052 ± 0.473
3.052ValGly: 3.052 ± 0.473
1.145ValHis: 1.145 ± 0.009
3.052ValIle: 3.052 ± 0.473
3.434ValLys: 3.434 ± 0.701
1.526ValLeu: 1.526 ± 0.437
2.671ValMet: 2.671 ± 1.101
3.434ValAsn: 3.434 ± 0.027
2.671ValPro: 2.671 ± 0.246
2.289ValGln: 2.289 ± 0.018
3.434ValArg: 3.434 ± 0.701
6.868ValSer: 6.868 ± 1.966
4.578ValThr: 4.578 ± 1.984
3.052ValVal: 3.052 ± 0.473
0.763ValTrp: 0.763 ± 0.455
3.815ValTyr: 3.815 ± 1.092
0.0ValXaa: 0.0 ± 0.0
Trp
1.145TrpAla: 1.145 ± 0.683
0.763TrpCys: 0.763 ± 0.455
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.763TrpPhe: 0.763 ± 0.218
1.145TrpGly: 1.145 ± 0.009
0.382TrpHis: 0.382 ± 0.228
0.763TrpIle: 0.763 ± 0.892
1.145TrpLys: 1.145 ± 0.009
1.526TrpLeu: 1.526 ± 0.237
0.382TrpMet: 0.382 ± 0.446
0.382TrpAsn: 0.382 ± 0.446
0.763TrpPro: 0.763 ± 0.218
0.382TrpGln: 0.382 ± 0.228
1.145TrpArg: 1.145 ± 0.009
0.382TrpSer: 0.382 ± 0.228
0.382TrpThr: 0.382 ± 0.446
0.763TrpVal: 0.763 ± 0.455
0.0TrpTrp: 0.0 ± 0.0
0.382TrpTyr: 0.382 ± 0.446
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.434TyrAla: 3.434 ± 0.027
0.0TyrCys: 0.0 ± 0.0
1.145TyrAsp: 1.145 ± 0.009
1.908TyrGlu: 1.908 ± 1.138
1.908TyrPhe: 1.908 ± 1.556
3.434TyrGly: 3.434 ± 0.027
1.145TyrHis: 1.145 ± 0.683
1.526TyrIle: 1.526 ± 0.237
1.145TyrLys: 1.145 ± 0.009
4.578TyrLeu: 4.578 ± 1.31
0.0TyrMet: 0.0 ± 0.0
1.908TyrAsn: 1.908 ± 0.209
1.145TyrPro: 1.145 ± 0.009
1.145TyrGln: 1.145 ± 0.683
2.671TyrArg: 2.671 ± 1.101
4.197TyrSer: 4.197 ± 0.191
3.434TyrThr: 3.434 ± 0.646
3.052TyrVal: 3.052 ± 1.547
0.763TyrTrp: 0.763 ± 0.218
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2622 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski