Amino acid dipepetide frequency for Dishui Lake virophage 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.225AlaCys: 0.225 ± 0.151
5.736AlaAsp: 5.736 ± 0.724
5.736AlaGlu: 5.736 ± 0.975
3.374AlaPhe: 3.374 ± 0.585
7.873AlaGly: 7.873 ± 1.765
0.9AlaHis: 0.9 ± 0.328
4.274AlaIle: 4.274 ± 0.527
4.611AlaLys: 4.611 ± 1.001
5.511AlaLeu: 5.511 ± 0.655
0.337AlaMet: 0.337 ± 0.197
5.174AlaAsn: 5.174 ± 0.793
4.949AlaPro: 4.949 ± 1.263
4.611AlaGln: 4.611 ± 0.848
3.149AlaArg: 3.149 ± 0.722
5.961AlaSer: 5.961 ± 0.923
7.761AlaThr: 7.761 ± 1.213
5.286AlaVal: 5.286 ± 0.874
0.675AlaTrp: 0.675 ± 0.25
2.587AlaTyr: 2.587 ± 0.365
0.0AlaXaa: 0.0 ± 0.0
Cys
0.225CysAla: 0.225 ± 0.146
0.9CysCys: 0.9 ± 0.334
0.45CysAsp: 0.45 ± 0.252
0.9CysGlu: 0.9 ± 0.343
0.562CysPhe: 0.562 ± 0.277
1.35CysGly: 1.35 ± 0.397
0.112CysHis: 0.112 ± 0.097
0.45CysIle: 0.45 ± 0.261
0.337CysLys: 0.337 ± 0.176
0.562CysLeu: 0.562 ± 0.217
0.45CysMet: 0.45 ± 0.207
0.787CysAsn: 0.787 ± 0.24
0.9CysPro: 0.9 ± 0.318
0.45CysGln: 0.45 ± 0.219
0.45CysArg: 0.45 ± 0.224
1.35CysSer: 1.35 ± 0.419
0.0CysThr: 0.0 ± 0.0
1.237CysVal: 1.237 ± 0.398
0.112CysTrp: 0.112 ± 0.12
0.225CysTyr: 0.225 ± 0.145
0.0CysXaa: 0.0 ± 0.0
Asp
4.499AspAla: 4.499 ± 0.655
0.675AspCys: 0.675 ± 0.25
4.162AspAsp: 4.162 ± 0.748
3.599AspGlu: 3.599 ± 0.611
3.374AspPhe: 3.374 ± 0.722
3.149AspGly: 3.149 ± 0.492
0.112AspHis: 0.112 ± 0.097
3.599AspIle: 3.599 ± 0.765
4.274AspLys: 4.274 ± 0.658
5.624AspLeu: 5.624 ± 0.589
1.687AspMet: 1.687 ± 0.415
2.025AspAsn: 2.025 ± 0.509
2.812AspPro: 2.812 ± 0.581
1.125AspGln: 1.125 ± 0.333
1.912AspArg: 1.912 ± 0.632
1.575AspSer: 1.575 ± 0.471
3.937AspThr: 3.937 ± 0.638
3.374AspVal: 3.374 ± 0.511
0.787AspTrp: 0.787 ± 0.48
3.487AspTyr: 3.487 ± 0.592
0.0AspXaa: 0.0 ± 0.0
Glu
5.624GluAla: 5.624 ± 0.937
0.562GluCys: 0.562 ± 0.288
4.049GluAsp: 4.049 ± 0.777
5.061GluGlu: 5.061 ± 1.483
1.912GluPhe: 1.912 ± 0.375
2.362GluGly: 2.362 ± 0.414
1.012GluHis: 1.012 ± 0.345
3.712GluIle: 3.712 ± 0.953
5.061GluLys: 5.061 ± 1.28
4.949GluLeu: 4.949 ± 0.935
1.125GluMet: 1.125 ± 0.443
3.487GluAsn: 3.487 ± 0.706
2.249GluPro: 2.249 ± 0.614
3.262GluGln: 3.262 ± 0.624
3.712GluArg: 3.712 ± 1.272
1.35GluSer: 1.35 ± 0.4
2.812GluThr: 2.812 ± 0.522
2.474GluVal: 2.474 ± 0.355
0.787GluTrp: 0.787 ± 0.264
3.149GluTyr: 3.149 ± 0.64
0.0GluXaa: 0.0 ± 0.0
Phe
2.924PheAla: 2.924 ± 0.753
0.787PheCys: 0.787 ± 0.236
2.025PheAsp: 2.025 ± 0.416
1.237PheGlu: 1.237 ± 0.475
2.812PhePhe: 2.812 ± 0.688
2.474PheGly: 2.474 ± 0.651
0.787PheHis: 0.787 ± 0.245
1.8PheIle: 1.8 ± 0.331
2.812PheLys: 2.812 ± 0.573
2.362PheLeu: 2.362 ± 0.394
1.012PheMet: 1.012 ± 0.268
2.362PheAsn: 2.362 ± 0.527
1.687PhePro: 1.687 ± 0.287
2.812PheGln: 2.812 ± 0.669
1.35PheArg: 1.35 ± 0.428
3.599PheSer: 3.599 ± 0.658
2.924PheThr: 2.924 ± 0.577
2.249PheVal: 2.249 ± 0.462
0.337PheTrp: 0.337 ± 0.265
1.012PheTyr: 1.012 ± 0.39
0.0PheXaa: 0.0 ± 0.0
Gly
5.849GlyAla: 5.849 ± 1.444
1.012GlyCys: 1.012 ± 0.338
5.174GlyAsp: 5.174 ± 1.305
3.712GlyGlu: 3.712 ± 0.639
1.687GlyPhe: 1.687 ± 0.553
14.959GlyGly: 14.959 ± 5.093
1.012GlyHis: 1.012 ± 0.266
3.374GlyIle: 3.374 ± 0.719
4.611GlyLys: 4.611 ± 1.014
4.836GlyLeu: 4.836 ± 0.885
2.362GlyMet: 2.362 ± 1.074
4.724GlyAsn: 4.724 ± 0.982
2.362GlyPro: 2.362 ± 1.469
3.149GlyGln: 3.149 ± 0.622
3.712GlyArg: 3.712 ± 0.664
6.186GlySer: 6.186 ± 1.051
4.724GlyThr: 4.724 ± 1.049
5.174GlyVal: 5.174 ± 0.677
0.675GlyTrp: 0.675 ± 0.241
2.924GlyTyr: 2.924 ± 0.842
0.0GlyXaa: 0.0 ± 0.0
His
1.35HisAla: 1.35 ± 0.385
0.0HisCys: 0.0 ± 0.0
0.787HisAsp: 0.787 ± 0.306
0.225HisGlu: 0.225 ± 0.206
0.675HisPhe: 0.675 ± 0.307
0.562HisGly: 0.562 ± 0.348
0.337HisHis: 0.337 ± 0.26
1.35HisIle: 1.35 ± 0.386
1.237HisLys: 1.237 ± 0.41
0.675HisLeu: 0.675 ± 0.324
0.112HisMet: 0.112 ± 0.097
1.012HisAsn: 1.012 ± 0.34
0.9HisPro: 0.9 ± 0.272
0.225HisGln: 0.225 ± 0.165
0.45HisArg: 0.45 ± 0.238
1.237HisSer: 1.237 ± 0.357
0.45HisThr: 0.45 ± 0.193
0.0HisVal: 0.0 ± 0.0
0.112HisTrp: 0.112 ± 0.115
0.337HisTyr: 0.337 ± 0.187
0.0HisXaa: 0.0 ± 0.0
Ile
4.274IleAla: 4.274 ± 0.52
1.012IleCys: 1.012 ± 0.314
2.587IleAsp: 2.587 ± 0.628
3.937IleGlu: 3.937 ± 0.559
1.912IlePhe: 1.912 ± 0.555
2.474IleGly: 2.474 ± 0.428
0.45IleHis: 0.45 ± 0.209
3.599IleIle: 3.599 ± 0.643
4.162IleLys: 4.162 ± 0.942
4.724IleLeu: 4.724 ± 0.703
1.575IleMet: 1.575 ± 0.361
2.699IleAsn: 2.699 ± 0.582
2.025IlePro: 2.025 ± 0.443
3.712IleGln: 3.712 ± 0.685
2.587IleArg: 2.587 ± 0.694
3.937IleSer: 3.937 ± 0.804
5.511IleThr: 5.511 ± 1.157
2.924IleVal: 2.924 ± 0.806
0.45IleTrp: 0.45 ± 0.219
2.587IleTyr: 2.587 ± 0.571
0.0IleXaa: 0.0 ± 0.0
Lys
5.511LysAla: 5.511 ± 1.355
0.675LysCys: 0.675 ± 0.247
3.487LysAsp: 3.487 ± 0.941
5.961LysGlu: 5.961 ± 1.378
2.025LysPhe: 2.025 ± 0.475
4.611LysGly: 4.611 ± 0.783
1.125LysHis: 1.125 ± 0.404
4.499LysIle: 4.499 ± 0.668
6.074LysLys: 6.074 ± 1.004
4.724LysLeu: 4.724 ± 0.873
2.137LysMet: 2.137 ± 0.458
3.149LysAsn: 3.149 ± 0.595
2.362LysPro: 2.362 ± 0.467
4.274LysGln: 4.274 ± 0.67
4.274LysArg: 4.274 ± 1.092
3.937LysSer: 3.937 ± 0.838
2.474LysThr: 2.474 ± 0.525
4.836LysVal: 4.836 ± 1.033
0.562LysTrp: 0.562 ± 0.297
3.149LysTyr: 3.149 ± 0.933
0.0LysXaa: 0.0 ± 0.0
Leu
5.286LeuAla: 5.286 ± 0.884
0.9LeuCys: 0.9 ± 0.255
5.174LeuAsp: 5.174 ± 0.751
4.162LeuGlu: 4.162 ± 0.671
2.587LeuPhe: 2.587 ± 0.639
5.961LeuGly: 5.961 ± 0.824
1.462LeuHis: 1.462 ± 0.498
3.374LeuIle: 3.374 ± 0.628
7.086LeuLys: 7.086 ± 1.251
6.861LeuLeu: 6.861 ± 0.776
1.125LeuMet: 1.125 ± 0.396
4.162LeuAsn: 4.162 ± 0.589
6.299LeuPro: 6.299 ± 0.784
3.037LeuGln: 3.037 ± 0.783
3.487LeuArg: 3.487 ± 0.71
5.849LeuSer: 5.849 ± 1.031
5.061LeuThr: 5.061 ± 0.818
2.812LeuVal: 2.812 ± 0.528
0.787LeuTrp: 0.787 ± 0.297
3.937LeuTyr: 3.937 ± 0.59
0.0LeuXaa: 0.0 ± 0.0
Met
1.012MetAla: 1.012 ± 0.35
0.675MetCys: 0.675 ± 0.385
1.125MetAsp: 1.125 ± 0.369
1.237MetGlu: 1.237 ± 0.433
0.9MetPhe: 0.9 ± 0.296
1.125MetGly: 1.125 ± 0.37
0.0MetHis: 0.0 ± 0.0
0.9MetIle: 0.9 ± 0.291
0.787MetLys: 0.787 ± 0.29
1.35MetLeu: 1.35 ± 0.442
0.337MetMet: 0.337 ± 0.154
1.462MetAsn: 1.462 ± 0.245
1.35MetPro: 1.35 ± 0.373
0.0MetGln: 0.0 ± 0.0
0.787MetArg: 0.787 ± 0.264
2.812MetSer: 2.812 ± 0.856
1.237MetThr: 1.237 ± 0.408
1.125MetVal: 1.125 ± 0.33
0.112MetTrp: 0.112 ± 0.098
0.45MetTyr: 0.45 ± 0.181
0.0MetXaa: 0.0 ± 0.0
Asn
5.624AsnAla: 5.624 ± 0.853
0.45AsnCys: 0.45 ± 0.223
2.812AsnAsp: 2.812 ± 0.703
2.474AsnGlu: 2.474 ± 0.674
1.462AsnPhe: 1.462 ± 0.535
3.487AsnGly: 3.487 ± 0.632
0.787AsnHis: 0.787 ± 0.296
3.712AsnIle: 3.712 ± 0.481
3.599AsnLys: 3.599 ± 0.736
4.836AsnLeu: 4.836 ± 0.558
1.35AsnMet: 1.35 ± 0.318
4.499AsnAsn: 4.499 ± 0.983
3.599AsnPro: 3.599 ± 0.417
2.025AsnGln: 2.025 ± 0.555
1.8AsnArg: 1.8 ± 0.472
4.499AsnSer: 4.499 ± 0.916
3.374AsnThr: 3.374 ± 0.918
2.362AsnVal: 2.362 ± 0.433
0.787AsnTrp: 0.787 ± 0.25
2.025AsnTyr: 2.025 ± 0.507
0.0AsnXaa: 0.0 ± 0.0
Pro
5.286ProAla: 5.286 ± 1.16
0.562ProCys: 0.562 ± 0.236
1.8ProAsp: 1.8 ± 0.487
2.924ProGlu: 2.924 ± 0.891
2.699ProPhe: 2.699 ± 0.767
0.0ProGly: 0.0 ± 0.0
0.45ProHis: 0.45 ± 0.188
2.025ProIle: 2.025 ± 0.425
3.037ProLys: 3.037 ± 0.594
4.949ProLeu: 4.949 ± 0.827
0.45ProMet: 0.45 ± 0.206
2.025ProAsn: 2.025 ± 0.431
2.812ProPro: 2.812 ± 1.366
3.937ProGln: 3.937 ± 0.916
1.912ProArg: 1.912 ± 0.376
3.149ProSer: 3.149 ± 0.554
3.937ProThr: 3.937 ± 0.806
3.824ProVal: 3.824 ± 0.471
0.562ProTrp: 0.562 ± 0.251
2.812ProTyr: 2.812 ± 0.718
0.0ProXaa: 0.0 ± 0.0
Gln
4.949GlnAla: 4.949 ± 1.066
0.0GlnCys: 0.0 ± 0.0
2.587GlnAsp: 2.587 ± 0.536
2.924GlnGlu: 2.924 ± 0.732
1.8GlnPhe: 1.8 ± 0.451
4.836GlnGly: 4.836 ± 1.549
0.562GlnHis: 0.562 ± 0.296
2.924GlnIle: 2.924 ± 0.397
2.362GlnLys: 2.362 ± 0.622
4.386GlnLeu: 4.386 ± 0.634
0.45GlnMet: 0.45 ± 0.194
1.8GlnAsn: 1.8 ± 0.509
2.362GlnPro: 2.362 ± 0.666
3.937GlnGln: 3.937 ± 1.241
2.249GlnArg: 2.249 ± 0.38
3.374GlnSer: 3.374 ± 0.784
3.487GlnThr: 3.487 ± 0.413
2.249GlnVal: 2.249 ± 0.501
0.225GlnTrp: 0.225 ± 0.145
1.8GlnTyr: 1.8 ± 0.367
0.0GlnXaa: 0.0 ± 0.0
Arg
2.587ArgAla: 2.587 ± 0.515
0.225ArgCys: 0.225 ± 0.161
1.912ArgAsp: 1.912 ± 0.388
3.487ArgGlu: 3.487 ± 0.916
1.8ArgPhe: 1.8 ± 0.493
2.249ArgGly: 2.249 ± 0.504
0.337ArgHis: 0.337 ± 0.167
3.037ArgIle: 3.037 ± 0.555
4.162ArgLys: 4.162 ± 1.027
4.162ArgLeu: 4.162 ± 0.763
0.9ArgMet: 0.9 ± 0.297
1.912ArgAsn: 1.912 ± 0.485
2.249ArgPro: 2.249 ± 0.583
2.249ArgGln: 2.249 ± 0.703
3.487ArgArg: 3.487 ± 1.014
2.025ArgSer: 2.025 ± 0.439
1.575ArgThr: 1.575 ± 0.417
1.687ArgVal: 1.687 ± 0.344
0.562ArgTrp: 0.562 ± 0.272
1.912ArgTyr: 1.912 ± 0.424
0.0ArgXaa: 0.0 ± 0.0
Ser
6.299SerAla: 6.299 ± 1.252
0.787SerCys: 0.787 ± 0.307
2.249SerAsp: 2.249 ± 0.516
2.025SerGlu: 2.025 ± 0.404
2.812SerPhe: 2.812 ± 0.592
8.773SerGly: 8.773 ± 2.155
0.9SerHis: 0.9 ± 0.296
5.174SerIle: 5.174 ± 0.779
4.274SerLys: 4.274 ± 0.546
4.611SerLeu: 4.611 ± 0.645
0.675SerMet: 0.675 ± 0.339
4.949SerAsn: 4.949 ± 0.743
3.599SerPro: 3.599 ± 0.681
3.487SerGln: 3.487 ± 0.806
1.575SerArg: 1.575 ± 0.631
7.761SerSer: 7.761 ± 1.55
3.599SerThr: 3.599 ± 0.833
5.849SerVal: 5.849 ± 0.971
0.337SerTrp: 0.337 ± 0.195
2.025SerTyr: 2.025 ± 0.452
0.0SerXaa: 0.0 ± 0.0
Thr
7.086ThrAla: 7.086 ± 1.598
0.9ThrCys: 0.9 ± 0.314
3.037ThrAsp: 3.037 ± 0.575
2.587ThrGlu: 2.587 ± 0.705
2.362ThrPhe: 2.362 ± 0.468
6.748ThrGly: 6.748 ± 1.657
1.125ThrHis: 1.125 ± 0.372
3.374ThrIle: 3.374 ± 0.494
3.149ThrLys: 3.149 ± 0.798
5.061ThrLeu: 5.061 ± 1.126
0.675ThrMet: 0.675 ± 0.261
2.812ThrAsn: 2.812 ± 0.788
3.037ThrPro: 3.037 ± 0.575
3.824ThrGln: 3.824 ± 0.516
1.462ThrArg: 1.462 ± 0.358
3.712ThrSer: 3.712 ± 0.836
3.374ThrThr: 3.374 ± 1.049
2.025ThrVal: 2.025 ± 0.651
0.675ThrTrp: 0.675 ± 0.236
2.587ThrTyr: 2.587 ± 0.49
0.0ThrXaa: 0.0 ± 0.0
Val
6.299ValAla: 6.299 ± 1.255
0.562ValCys: 0.562 ± 0.246
2.249ValAsp: 2.249 ± 0.388
2.924ValGlu: 2.924 ± 0.664
2.362ValPhe: 2.362 ± 0.537
6.186ValGly: 6.186 ± 1.502
0.112ValHis: 0.112 ± 0.103
2.362ValIle: 2.362 ± 0.624
4.274ValLys: 4.274 ± 0.816
5.286ValLeu: 5.286 ± 0.619
0.9ValMet: 0.9 ± 0.395
3.599ValAsn: 3.599 ± 0.588
2.362ValPro: 2.362 ± 0.416
1.575ValGln: 1.575 ± 0.318
2.249ValArg: 2.249 ± 0.45
5.286ValSer: 5.286 ± 0.98
0.225ValThr: 0.225 ± 0.241
4.049ValVal: 4.049 ± 0.841
0.675ValTrp: 0.675 ± 0.24
2.474ValTyr: 2.474 ± 0.52
0.0ValXaa: 0.0 ± 0.0
Trp
0.562TrpAla: 0.562 ± 0.218
0.45TrpCys: 0.45 ± 0.197
0.9TrpAsp: 0.9 ± 0.327
0.675TrpGlu: 0.675 ± 0.221
0.675TrpPhe: 0.675 ± 0.22
0.45TrpGly: 0.45 ± 0.262
0.0TrpHis: 0.0 ± 0.0
0.9TrpIle: 0.9 ± 0.321
0.675TrpLys: 0.675 ± 0.255
0.787TrpLeu: 0.787 ± 0.372
0.0TrpMet: 0.0 ± 0.0
1.012TrpAsn: 1.012 ± 0.266
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.562TrpArg: 0.562 ± 0.218
0.787TrpSer: 0.787 ± 0.415
0.562TrpThr: 0.562 ± 0.243
0.562TrpVal: 0.562 ± 0.272
0.112TrpTrp: 0.112 ± 0.097
0.337TrpTyr: 0.337 ± 0.194
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.487TyrAla: 3.487 ± 0.588
0.45TyrCys: 0.45 ± 0.213
3.487TyrAsp: 3.487 ± 0.645
2.924TyrGlu: 2.924 ± 0.537
1.575TyrPhe: 1.575 ± 0.508
2.587TyrGly: 2.587 ± 0.549
0.45TyrHis: 0.45 ± 0.215
2.699TyrIle: 2.699 ± 0.561
3.262TyrLys: 3.262 ± 0.591
3.149TyrLeu: 3.149 ± 0.622
1.012TyrMet: 1.012 ± 0.348
2.025TyrAsn: 2.025 ± 0.382
1.237TyrPro: 1.237 ± 0.396
1.575TyrGln: 1.575 ± 0.672
1.35TyrArg: 1.35 ± 0.403
3.374TyrSer: 3.374 ± 0.616
2.587TyrThr: 2.587 ± 0.558
1.912TyrVal: 1.912 ± 0.452
0.675TyrTrp: 0.675 ± 0.233
2.474TyrTyr: 2.474 ± 0.756
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 27 proteins (8892 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski