Amino acid dipepetide frequency for Hubei rhabdo-like virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.364AlaAla: 4.364 ± 2.079
0.546AlaCys: 0.546 ± 0.311
2.728AlaAsp: 2.728 ± 0.576
1.364AlaGlu: 1.364 ± 0.594
2.455AlaPhe: 2.455 ± 0.59
3.819AlaGly: 3.819 ± 1.88
1.637AlaHis: 1.637 ± 0.365
3.819AlaIle: 3.819 ± 0.953
2.182AlaLys: 2.182 ± 1.651
4.91AlaLeu: 4.91 ± 1.28
0.546AlaMet: 0.546 ± 0.311
1.091AlaAsn: 1.091 ± 0.494
0.546AlaPro: 0.546 ± 0.321
1.909AlaGln: 1.909 ± 0.768
4.092AlaArg: 4.092 ± 1.07
6.001AlaSer: 6.001 ± 1.444
1.909AlaThr: 1.909 ± 0.382
1.091AlaVal: 1.091 ± 0.641
0.546AlaTrp: 0.546 ± 0.559
2.728AlaTyr: 2.728 ± 0.724
0.0AlaXaa: 0.0 ± 0.0
Cys
1.091CysAla: 1.091 ± 0.374
0.0CysCys: 0.0 ± 0.0
2.455CysAsp: 2.455 ± 0.647
0.546CysGlu: 0.546 ± 0.559
1.091CysPhe: 1.091 ± 0.374
0.0CysGly: 0.0 ± 0.0
0.273CysHis: 0.273 ± 0.16
1.909CysIle: 1.909 ± 0.691
1.091CysLys: 1.091 ± 0.711
1.909CysLeu: 1.909 ± 0.485
0.546CysMet: 0.546 ± 0.248
0.273CysAsn: 0.273 ± 0.295
0.546CysPro: 0.546 ± 0.248
0.546CysGln: 0.546 ± 0.321
0.0CysArg: 0.0 ± 0.0
1.091CysSer: 1.091 ± 0.654
0.546CysThr: 0.546 ± 0.341
1.364CysVal: 1.364 ± 0.521
0.273CysTrp: 0.273 ± 0.16
1.364CysTyr: 1.364 ± 0.606
0.0CysXaa: 0.0 ± 0.0
Asp
1.637AspAla: 1.637 ± 0.871
0.546AspCys: 0.546 ± 0.446
3.273AspAsp: 3.273 ± 0.828
3.546AspGlu: 3.546 ± 2.223
2.182AspPhe: 2.182 ± 0.421
2.455AspGly: 2.455 ± 0.999
2.182AspHis: 2.182 ± 0.718
4.364AspIle: 4.364 ± 1.277
2.182AspLys: 2.182 ± 0.739
5.728AspLeu: 5.728 ± 0.91
1.091AspMet: 1.091 ± 0.376
4.092AspAsn: 4.092 ± 1.777
3.546AspPro: 3.546 ± 0.804
1.637AspGln: 1.637 ± 0.566
2.182AspArg: 2.182 ± 0.991
4.092AspSer: 4.092 ± 2.335
3.001AspThr: 3.001 ± 0.772
4.637AspVal: 4.637 ± 0.621
0.818AspTrp: 0.818 ± 0.295
2.455AspTyr: 2.455 ± 1.443
0.0AspXaa: 0.0 ± 0.0
Glu
3.273GluAla: 3.273 ± 1.86
2.455GluCys: 2.455 ± 0.734
3.819GluAsp: 3.819 ± 0.72
4.637GluGlu: 4.637 ± 1.038
1.637GluPhe: 1.637 ± 0.484
2.455GluGly: 2.455 ± 0.856
1.091GluHis: 1.091 ± 0.3
4.91GluIle: 4.91 ± 0.801
5.456GluLys: 5.456 ± 1.292
6.274GluLeu: 6.274 ± 2.07
1.364GluMet: 1.364 ± 0.594
1.364GluAsn: 1.364 ± 0.678
1.091GluPro: 1.091 ± 0.535
1.364GluGln: 1.364 ± 0.802
4.092GluArg: 4.092 ± 0.607
4.092GluSer: 4.092 ± 0.969
2.182GluThr: 2.182 ± 1.025
3.273GluVal: 3.273 ± 0.625
0.273GluTrp: 0.273 ± 0.16
0.818GluTyr: 0.818 ± 0.449
0.0GluXaa: 0.0 ± 0.0
Phe
1.909PheAla: 1.909 ± 0.527
1.091PheCys: 1.091 ± 0.411
2.455PheAsp: 2.455 ± 0.626
2.455PheGlu: 2.455 ± 1.142
3.001PhePhe: 3.001 ± 1.014
0.818PheGly: 0.818 ± 0.551
0.546PheHis: 0.546 ± 0.321
2.728PheIle: 2.728 ± 0.706
1.637PheLys: 1.637 ± 0.483
5.456PheLeu: 5.456 ± 1.229
0.818PheMet: 0.818 ± 0.481
3.001PheAsn: 3.001 ± 0.788
1.364PhePro: 1.364 ± 0.802
0.273PheGln: 0.273 ± 0.39
1.091PheArg: 1.091 ± 0.374
5.183PheSer: 5.183 ± 0.98
1.909PheThr: 1.909 ± 0.485
1.637PheVal: 1.637 ± 0.591
0.273PheTrp: 0.273 ± 0.16
1.909PheTyr: 1.909 ± 0.649
0.0PheXaa: 0.0 ± 0.0
Gly
1.909GlyAla: 1.909 ± 0.721
1.637GlyCys: 1.637 ± 0.547
1.364GlyAsp: 1.364 ± 0.541
2.182GlyGlu: 2.182 ± 0.549
2.455GlyPhe: 2.455 ± 0.567
2.455GlyGly: 2.455 ± 1.071
2.182GlyHis: 2.182 ± 0.811
5.183GlyIle: 5.183 ± 1.027
2.455GlyLys: 2.455 ± 0.527
4.91GlyLeu: 4.91 ± 1.402
0.273GlyMet: 0.273 ± 0.397
2.455GlyAsn: 2.455 ± 0.841
1.091GlyPro: 1.091 ± 0.444
1.364GlyGln: 1.364 ± 0.594
2.182GlyArg: 2.182 ± 0.972
4.637GlySer: 4.637 ± 1.592
2.728GlyThr: 2.728 ± 1.077
3.001GlyVal: 3.001 ± 1.01
0.273GlyTrp: 0.273 ± 0.16
2.182GlyTyr: 2.182 ± 0.853
0.0GlyXaa: 0.0 ± 0.0
His
2.455HisAla: 2.455 ± 0.688
0.273HisCys: 0.273 ± 0.16
0.818HisAsp: 0.818 ± 0.295
1.364HisGlu: 1.364 ± 0.541
0.818HisPhe: 0.818 ± 0.921
1.637HisGly: 1.637 ± 0.365
0.818HisHis: 0.818 ± 0.52
1.637HisIle: 1.637 ± 0.484
0.546HisLys: 0.546 ± 0.5
2.728HisLeu: 2.728 ± 0.766
1.091HisMet: 1.091 ± 0.464
1.091HisAsn: 1.091 ± 0.444
2.455HisPro: 2.455 ± 0.784
1.909HisGln: 1.909 ± 0.507
1.637HisArg: 1.637 ± 0.962
0.546HisSer: 0.546 ± 0.311
1.637HisThr: 1.637 ± 0.623
2.182HisVal: 2.182 ± 0.754
0.818HisTrp: 0.818 ± 0.481
1.091HisTyr: 1.091 ± 0.34
0.0HisXaa: 0.0 ± 0.0
Ile
4.364IleAla: 4.364 ± 1.017
1.637IleCys: 1.637 ± 0.496
4.092IleAsp: 4.092 ± 0.719
5.456IleGlu: 5.456 ± 1.969
3.001IlePhe: 3.001 ± 1.373
2.182IleGly: 2.182 ± 0.903
3.001IleHis: 3.001 ± 1.074
7.638IleIle: 7.638 ± 1.644
6.001IleLys: 6.001 ± 0.884
11.729IleLeu: 11.729 ± 1.75
1.637IleMet: 1.637 ± 0.419
2.182IleAsn: 2.182 ± 0.666
4.91IlePro: 4.91 ± 0.709
1.909IleGln: 1.909 ± 0.449
2.455IleArg: 2.455 ± 0.604
7.911IleSer: 7.911 ± 1.97
4.092IleThr: 4.092 ± 1.075
4.092IleVal: 4.092 ± 0.435
1.091IleTrp: 1.091 ± 0.34
2.182IleTyr: 2.182 ± 0.81
0.0IleXaa: 0.0 ± 0.0
Lys
1.909LysAla: 1.909 ± 1.445
0.273LysCys: 0.273 ± 0.16
4.092LysAsp: 4.092 ± 0.95
4.91LysGlu: 4.91 ± 1.478
2.182LysPhe: 2.182 ± 0.607
2.182LysGly: 2.182 ± 0.242
0.818LysHis: 0.818 ± 0.33
7.092LysIle: 7.092 ± 0.561
9.547LysLys: 9.547 ± 6.619
3.273LysLeu: 3.273 ± 1.051
1.091LysMet: 1.091 ± 0.649
3.273LysAsn: 3.273 ± 1.07
1.364LysPro: 1.364 ± 1.15
2.182LysGln: 2.182 ± 1.561
3.819LysArg: 3.819 ± 1.278
7.638LysSer: 7.638 ± 2.342
4.637LysThr: 4.637 ± 1.685
5.183LysVal: 5.183 ± 1.908
1.091LysTrp: 1.091 ± 0.641
2.182LysTyr: 2.182 ± 0.662
0.0LysXaa: 0.0 ± 0.0
Leu
4.91LeuAla: 4.91 ± 1.208
1.364LeuCys: 1.364 ± 0.51
4.364LeuAsp: 4.364 ± 0.771
6.547LeuGlu: 6.547 ± 1.171
4.91LeuPhe: 4.91 ± 1.885
5.456LeuGly: 5.456 ± 1.433
3.001LeuHis: 3.001 ± 0.817
8.456LeuIle: 8.456 ± 0.782
7.911LeuLys: 7.911 ± 1.371
14.184LeuLeu: 14.184 ± 2.805
2.182LeuMet: 2.182 ± 0.554
6.819LeuAsn: 6.819 ± 2.201
6.547LeuPro: 6.547 ± 2.204
3.001LeuGln: 3.001 ± 0.928
6.001LeuArg: 6.001 ± 1.713
13.093LeuSer: 13.093 ± 2.419
6.001LeuThr: 6.001 ± 0.898
5.728LeuVal: 5.728 ± 1.447
1.637LeuTrp: 1.637 ± 0.432
3.273LeuTyr: 3.273 ± 0.867
0.0LeuXaa: 0.0 ± 0.0
Met
0.273MetAla: 0.273 ± 0.397
0.273MetCys: 0.273 ± 0.296
1.364MetAsp: 1.364 ± 0.678
1.091MetGlu: 1.091 ± 0.406
0.273MetPhe: 0.273 ± 0.491
0.818MetGly: 0.818 ± 0.381
0.546MetHis: 0.546 ± 0.321
1.909MetIle: 1.909 ± 0.766
1.091MetLys: 1.091 ± 0.374
1.909MetLeu: 1.909 ± 0.392
1.091MetMet: 1.091 ± 0.406
0.546MetAsn: 0.546 ± 0.504
0.273MetPro: 0.273 ± 0.16
0.546MetGln: 0.546 ± 0.321
1.364MetArg: 1.364 ± 0.541
3.273MetSer: 3.273 ± 1.453
1.637MetThr: 1.637 ± 1.148
1.364MetVal: 1.364 ± 0.528
0.546MetTrp: 0.546 ± 0.321
0.273MetTyr: 0.273 ± 0.16
0.0MetXaa: 0.0 ± 0.0
Asn
1.909AsnAla: 1.909 ± 0.498
0.818AsnCys: 0.818 ± 0.449
0.818AsnAsp: 0.818 ± 0.879
1.909AsnGlu: 1.909 ± 0.824
1.637AsnPhe: 1.637 ± 0.481
0.818AsnGly: 0.818 ± 0.481
1.637AsnHis: 1.637 ± 0.453
5.728AsnIle: 5.728 ± 1.395
4.364AsnLys: 4.364 ± 0.681
6.274AsnLeu: 6.274 ± 1.765
1.091AsnMet: 1.091 ± 0.344
1.637AsnAsn: 1.637 ± 1.357
4.092AsnPro: 4.092 ± 1.441
2.455AsnGln: 2.455 ± 0.767
2.182AsnArg: 2.182 ± 0.982
2.455AsnSer: 2.455 ± 0.817
1.909AsnThr: 1.909 ± 0.768
0.818AsnVal: 0.818 ± 0.436
0.546AsnTrp: 0.546 ± 0.311
2.728AsnTyr: 2.728 ± 0.862
0.0AsnXaa: 0.0 ± 0.0
Pro
1.909ProAla: 1.909 ± 0.485
0.818ProCys: 0.818 ± 0.295
4.637ProAsp: 4.637 ± 0.886
1.364ProGlu: 1.364 ± 0.488
1.637ProPhe: 1.637 ± 0.483
3.001ProGly: 3.001 ± 0.73
1.909ProHis: 1.909 ± 0.586
3.001ProIle: 3.001 ± 1.18
2.728ProLys: 2.728 ± 0.959
4.364ProLeu: 4.364 ± 1.01
0.273ProMet: 0.273 ± 0.39
2.455ProAsn: 2.455 ± 0.784
1.637ProPro: 1.637 ± 0.591
1.091ProGln: 1.091 ± 0.432
2.182ProArg: 2.182 ± 0.968
3.273ProSer: 3.273 ± 1.136
2.455ProThr: 2.455 ± 0.716
2.182ProVal: 2.182 ± 0.68
0.546ProTrp: 0.546 ± 0.571
2.182ProTyr: 2.182 ± 0.68
0.0ProXaa: 0.0 ± 0.0
Gln
2.455GlnAla: 2.455 ± 1.073
0.546GlnCys: 0.546 ± 0.248
2.182GlnAsp: 2.182 ± 0.52
1.909GlnGlu: 1.909 ± 0.547
1.364GlnPhe: 1.364 ± 0.348
1.637GlnGly: 1.637 ± 0.493
1.091GlnHis: 1.091 ± 0.406
2.455GlnIle: 2.455 ± 0.752
1.364GlnLys: 1.364 ± 0.488
3.546GlnLeu: 3.546 ± 0.72
0.546GlnMet: 0.546 ± 0.248
1.364GlnAsn: 1.364 ± 0.548
0.818GlnPro: 0.818 ± 0.478
0.546GlnGln: 0.546 ± 0.321
0.546GlnArg: 0.546 ± 0.311
1.909GlnSer: 1.909 ± 0.64
2.182GlnThr: 2.182 ± 0.589
2.728GlnVal: 2.728 ± 0.652
0.273GlnTrp: 0.273 ± 0.16
1.637GlnTyr: 1.637 ± 0.558
0.0GlnXaa: 0.0 ± 0.0
Arg
3.001ArgAla: 3.001 ± 1.564
0.546ArgCys: 0.546 ± 0.311
3.546ArgAsp: 3.546 ± 1.063
3.001ArgGlu: 3.001 ± 0.82
0.818ArgPhe: 0.818 ± 0.449
3.001ArgGly: 3.001 ± 1.206
0.273ArgHis: 0.273 ± 0.16
4.91ArgIle: 4.91 ± 0.429
1.637ArgLys: 1.637 ± 0.743
5.183ArgLeu: 5.183 ± 2.697
1.364ArgMet: 1.364 ± 0.313
1.909ArgAsn: 1.909 ± 0.574
2.455ArgPro: 2.455 ± 0.872
0.818ArgGln: 0.818 ± 0.481
3.273ArgArg: 3.273 ± 1.092
4.637ArgSer: 4.637 ± 0.74
4.092ArgThr: 4.092 ± 1.363
3.273ArgVal: 3.273 ± 0.441
0.546ArgTrp: 0.546 ± 0.248
2.182ArgTyr: 2.182 ± 0.788
0.0ArgXaa: 0.0 ± 0.0
Ser
5.183SerAla: 5.183 ± 0.952
1.091SerCys: 1.091 ± 0.432
6.819SerAsp: 6.819 ± 3.292
5.728SerGlu: 5.728 ± 1.367
3.273SerPhe: 3.273 ± 2.048
6.001SerGly: 6.001 ± 2.691
4.364SerHis: 4.364 ± 1.504
5.456SerIle: 5.456 ± 0.796
6.001SerLys: 6.001 ± 2.096
11.457SerLeu: 11.457 ± 2.113
2.182SerMet: 2.182 ± 1.385
4.092SerAsn: 4.092 ± 1.143
2.455SerPro: 2.455 ± 0.463
4.364SerGln: 4.364 ± 0.294
6.274SerArg: 6.274 ± 1.716
10.638SerSer: 10.638 ± 1.709
3.273SerThr: 3.273 ± 1.909
3.819SerVal: 3.819 ± 1.341
0.818SerTrp: 0.818 ± 0.295
1.909SerTyr: 1.909 ± 0.64
0.0SerXaa: 0.0 ± 0.0
Thr
1.909ThrAla: 1.909 ± 0.547
0.818ThrCys: 0.818 ± 0.355
3.819ThrAsp: 3.819 ± 0.744
3.819ThrGlu: 3.819 ± 0.735
1.091ThrPhe: 1.091 ± 0.34
3.546ThrGly: 3.546 ± 0.709
0.273ThrHis: 0.273 ± 0.16
4.092ThrIle: 4.092 ± 0.993
3.273ThrLys: 3.273 ± 1.555
9.002ThrLeu: 9.002 ± 0.898
1.091ThrMet: 1.091 ± 0.761
1.637ThrAsn: 1.637 ± 0.365
3.001ThrPro: 3.001 ± 0.563
1.637ThrGln: 1.637 ± 0.524
2.455ThrArg: 2.455 ± 0.729
6.274ThrSer: 6.274 ± 2.245
3.546ThrThr: 3.546 ± 0.922
2.455ThrVal: 2.455 ± 0.65
0.273ThrTrp: 0.273 ± 0.16
0.818ThrTyr: 0.818 ± 0.436
0.0ThrXaa: 0.0 ± 0.0
Val
1.637ValAla: 1.637 ± 0.378
0.818ValCys: 0.818 ± 0.481
1.091ValAsp: 1.091 ± 0.641
2.455ValGlu: 2.455 ± 0.454
2.455ValPhe: 2.455 ± 1.15
1.909ValGly: 1.909 ± 0.514
1.091ValHis: 1.091 ± 0.508
3.819ValIle: 3.819 ± 0.461
6.274ValLys: 6.274 ± 2.098
6.274ValLeu: 6.274 ± 0.625
0.818ValMet: 0.818 ± 0.355
2.728ValAsn: 2.728 ± 0.724
3.819ValPro: 3.819 ± 1.177
2.182ValGln: 2.182 ± 1.055
3.546ValArg: 3.546 ± 0.483
4.637ValSer: 4.637 ± 0.659
2.728ValThr: 2.728 ± 1.307
3.273ValVal: 3.273 ± 1.627
1.091ValTrp: 1.091 ± 0.3
1.909ValTyr: 1.909 ± 0.547
0.0ValXaa: 0.0 ± 0.0
Trp
0.818TrpAla: 0.818 ± 0.481
0.273TrpCys: 0.273 ± 0.16
0.0TrpAsp: 0.0 ± 0.0
1.091TrpGlu: 1.091 ± 0.34
1.091TrpPhe: 1.091 ± 0.641
0.818TrpGly: 0.818 ± 0.481
0.0TrpHis: 0.0 ± 0.0
1.091TrpIle: 1.091 ± 0.495
0.546TrpLys: 0.546 ± 0.321
0.818TrpLeu: 0.818 ± 0.381
0.273TrpMet: 0.273 ± 0.16
1.091TrpAsn: 1.091 ± 0.406
0.273TrpPro: 0.273 ± 0.16
0.0TrpGln: 0.0 ± 0.0
0.273TrpArg: 0.273 ± 0.39
0.546TrpSer: 0.546 ± 0.442
2.182TrpThr: 2.182 ± 0.68
0.546TrpVal: 0.546 ± 0.321
0.0TrpTrp: 0.0 ± 0.0
0.273TrpTyr: 0.273 ± 0.39
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.364TyrAla: 1.364 ± 0.313
1.091TyrCys: 1.091 ± 0.3
1.909TyrAsp: 1.909 ± 0.418
0.546TyrGlu: 0.546 ± 0.5
2.182TyrPhe: 2.182 ± 0.512
1.909TyrGly: 1.909 ± 0.706
0.818TyrHis: 0.818 ± 0.33
1.364TyrIle: 1.364 ± 0.521
2.728TyrLys: 2.728 ± 1.949
5.456TyrLeu: 5.456 ± 1.572
0.818TyrMet: 0.818 ± 0.418
2.728TyrAsn: 2.728 ± 0.696
1.364TyrPro: 1.364 ± 0.594
1.364TyrGln: 1.364 ± 0.293
0.818TyrArg: 0.818 ± 0.449
3.273TyrSer: 3.273 ± 1.167
2.182TyrThr: 2.182 ± 0.811
1.909TyrVal: 1.909 ± 0.768
0.273TyrTrp: 0.273 ± 0.16
1.364TyrTyr: 1.364 ± 0.488
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3667 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski