Amino acid dipepetide frequency for Beihai picorna-like virus 49

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.971AlaAla: 2.971 ± 0.189
1.273AlaCys: 1.273 ± 0.007
4.244AlaAsp: 4.244 ± 0.796
2.547AlaGlu: 2.547 ± 1.215
2.122AlaPhe: 2.122 ± 1.013
4.669AlaGly: 4.669 ± 2.074
3.396AlaHis: 3.396 ± 1.62
2.971AlaIle: 2.971 ± 0.803
2.122AlaLys: 2.122 ± 1.013
8.489AlaLeu: 8.489 ± 1.48
1.698AlaMet: 1.698 ± 0.725
2.122AlaAsn: 2.122 ± 0.831
4.244AlaPro: 4.244 ± 1.662
2.547AlaGln: 2.547 ± 0.014
2.547AlaArg: 2.547 ± 0.014
6.791AlaSer: 6.791 ± 2.29
2.971AlaThr: 2.971 ± 1.04
4.669AlaVal: 4.669 ± 1.459
0.849AlaTrp: 0.849 ± 0.824
1.698AlaTyr: 1.698 ± 0.419
0.0AlaXaa: 0.0 ± 0.0
Cys
0.849CysAla: 0.849 ± 0.824
0.424CysCys: 0.424 ± 0.412
1.698CysAsp: 1.698 ± 0.196
2.971CysGlu: 2.971 ± 1.418
0.424CysPhe: 0.424 ± 0.203
1.273CysGly: 1.273 ± 0.608
0.424CysHis: 0.424 ± 0.203
0.849CysIle: 0.849 ± 0.405
0.849CysLys: 0.849 ± 0.405
1.698CysLeu: 1.698 ± 0.196
0.0CysMet: 0.0 ± 0.0
0.424CysAsn: 0.424 ± 0.203
1.698CysPro: 1.698 ± 0.196
0.0CysGln: 0.0 ± 0.0
0.424CysArg: 0.424 ± 0.203
0.424CysSer: 0.424 ± 0.203
1.698CysThr: 1.698 ± 1.033
2.122CysVal: 2.122 ± 0.216
0.0CysTrp: 0.0 ± 0.0
2.122CysTyr: 2.122 ± 1.445
0.0CysXaa: 0.0 ± 0.0
Asp
1.698AspAla: 1.698 ± 0.196
0.849AspCys: 0.849 ± 0.405
3.396AspAsp: 3.396 ± 0.838
5.093AspGlu: 5.093 ± 0.028
2.971AspPhe: 2.971 ± 0.803
1.273AspGly: 1.273 ± 0.621
0.849AspHis: 0.849 ± 0.405
5.942AspIle: 5.942 ± 0.237
4.669AspLys: 4.669 ± 0.999
4.669AspLeu: 4.669 ± 0.23
1.273AspMet: 1.273 ± 0.007
2.971AspAsn: 2.971 ± 0.189
4.669AspPro: 4.669 ± 1.459
0.0AspGln: 0.0 ± 0.0
1.698AspArg: 1.698 ± 0.81
3.396AspSer: 3.396 ± 0.391
3.82AspThr: 3.82 ± 0.635
5.942AspVal: 5.942 ± 0.377
0.849AspTrp: 0.849 ± 0.405
1.698AspTyr: 1.698 ± 0.419
0.0AspXaa: 0.0 ± 0.0
Glu
4.244GluAla: 4.244 ± 1.411
1.273GluCys: 1.273 ± 0.007
2.122GluAsp: 2.122 ± 0.398
2.547GluGlu: 2.547 ± 1.215
2.547GluPhe: 2.547 ± 0.601
1.273GluGly: 1.273 ± 0.608
0.424GluHis: 0.424 ± 0.203
2.122GluIle: 2.122 ± 0.398
3.396GluLys: 3.396 ± 1.62
7.64GluLeu: 7.64 ± 0.573
1.273GluMet: 1.273 ± 0.007
2.122GluAsn: 2.122 ± 0.831
0.849GluPro: 0.849 ± 0.405
0.424GluGln: 0.424 ± 0.412
2.122GluArg: 2.122 ± 0.216
3.396GluSer: 3.396 ± 1.006
2.547GluThr: 2.547 ± 0.014
2.971GluVal: 2.971 ± 1.418
0.424GluTrp: 0.424 ± 0.203
3.396GluTyr: 3.396 ± 1.006
0.0GluXaa: 0.0 ± 0.0
Phe
2.547PheAla: 2.547 ± 1.243
0.849PheCys: 0.849 ± 0.405
3.82PheAsp: 3.82 ± 0.594
3.82PheGlu: 3.82 ± 1.208
3.82PhePhe: 3.82 ± 0.021
5.093PheGly: 5.093 ± 1.257
1.273PheHis: 1.273 ± 0.007
2.547PheIle: 2.547 ± 0.014
2.971PheLys: 2.971 ± 0.803
5.942PheLeu: 5.942 ± 0.377
1.273PheMet: 1.273 ± 0.608
2.971PheAsn: 2.971 ± 0.803
2.122PhePro: 2.122 ± 0.398
1.698PheGln: 1.698 ± 0.196
3.396PheArg: 3.396 ± 1.006
2.971PheSer: 2.971 ± 0.803
2.971PheThr: 2.971 ± 0.426
3.82PheVal: 3.82 ± 0.021
0.849PheTrp: 0.849 ± 0.405
2.971PheTyr: 2.971 ± 0.426
0.0PheXaa: 0.0 ± 0.0
Gly
3.82GlyAla: 3.82 ± 1.864
0.849GlyCys: 0.849 ± 0.209
3.82GlyAsp: 3.82 ± 1.208
2.971GlyGlu: 2.971 ± 1.655
5.093GlyPhe: 5.093 ± 0.642
2.971GlyGly: 2.971 ± 1.04
0.849GlyHis: 0.849 ± 0.209
1.698GlyIle: 1.698 ± 0.81
3.396GlyLys: 3.396 ± 1.62
3.396GlyLeu: 3.396 ± 0.223
1.273GlyMet: 1.273 ± 0.621
3.82GlyAsn: 3.82 ± 1.864
0.849GlyPro: 0.849 ± 0.209
2.122GlyGln: 2.122 ± 0.398
2.122GlyArg: 2.122 ± 0.831
4.244GlySer: 4.244 ± 3.505
5.518GlyThr: 5.518 ± 0.44
5.518GlyVal: 5.518 ± 0.789
1.698GlyTrp: 1.698 ± 0.81
1.698GlyTyr: 1.698 ± 0.419
0.0GlyXaa: 0.0 ± 0.0
His
0.424HisAla: 0.424 ± 0.203
0.424HisCys: 0.424 ± 0.203
0.424HisAsp: 0.424 ± 0.203
1.698HisGlu: 1.698 ± 0.81
2.122HisPhe: 2.122 ± 0.398
1.698HisGly: 1.698 ± 0.196
0.849HisHis: 0.849 ± 0.405
1.273HisIle: 1.273 ± 0.007
0.849HisLys: 0.849 ± 0.209
3.396HisLeu: 3.396 ± 0.391
0.424HisMet: 0.424 ± 0.203
0.424HisAsn: 0.424 ± 0.203
1.273HisPro: 1.273 ± 0.007
0.424HisGln: 0.424 ± 0.412
0.424HisArg: 0.424 ± 0.412
1.698HisSer: 1.698 ± 0.196
2.547HisThr: 2.547 ± 0.014
0.424HisVal: 0.424 ± 0.203
0.424HisTrp: 0.424 ± 0.412
0.424HisTyr: 0.424 ± 0.203
0.0HisXaa: 0.0 ± 0.0
Ile
2.547IleAla: 2.547 ± 0.628
1.698IleCys: 1.698 ± 0.196
3.396IleAsp: 3.396 ± 0.838
2.547IleGlu: 2.547 ± 0.628
3.396IlePhe: 3.396 ± 1.006
3.396IleGly: 3.396 ± 1.452
1.698IleHis: 1.698 ± 0.81
4.669IleIle: 4.669 ± 0.845
3.396IleLys: 3.396 ± 0.223
2.547IleLeu: 2.547 ± 0.601
0.424IleMet: 0.424 ± 0.203
3.396IleAsn: 3.396 ± 0.838
3.82IlePro: 3.82 ± 0.635
1.698IleGln: 1.698 ± 0.81
2.122IleArg: 2.122 ± 0.831
4.244IleSer: 4.244 ± 0.796
5.942IleThr: 5.942 ± 0.237
2.547IleVal: 2.547 ± 1.215
0.424IleTrp: 0.424 ± 0.203
0.849IleTyr: 0.849 ± 0.405
0.0IleXaa: 0.0 ± 0.0
Lys
5.518LysAla: 5.518 ± 2.018
1.273LysCys: 1.273 ± 0.608
3.82LysAsp: 3.82 ± 1.208
3.396LysGlu: 3.396 ± 1.006
2.971LysPhe: 2.971 ± 0.189
2.971LysGly: 2.971 ± 0.803
2.122LysHis: 2.122 ± 0.398
5.093LysIle: 5.093 ± 1.257
4.244LysLys: 4.244 ± 0.182
5.942LysLeu: 5.942 ± 0.992
1.698LysMet: 1.698 ± 0.81
1.698LysAsn: 1.698 ± 0.81
2.547LysPro: 2.547 ± 0.601
1.273LysGln: 1.273 ± 0.007
2.971LysArg: 2.971 ± 0.803
1.698LysSer: 1.698 ± 0.81
4.244LysThr: 4.244 ± 0.433
1.273LysVal: 1.273 ± 0.621
0.849LysTrp: 0.849 ± 0.405
4.244LysTyr: 4.244 ± 1.411
0.0LysXaa: 0.0 ± 0.0
Leu
8.065LeuAla: 8.065 ± 1.068
2.547LeuCys: 2.547 ± 0.628
5.093LeuAsp: 5.093 ± 0.028
2.971LeuGlu: 2.971 ± 1.418
6.367LeuPhe: 6.367 ± 1.264
5.518LeuGly: 5.518 ± 1.054
2.547LeuHis: 2.547 ± 0.628
0.849LeuIle: 0.849 ± 0.209
5.518LeuLys: 5.518 ± 0.789
8.913LeuLeu: 8.913 ± 0.566
2.122LeuMet: 2.122 ± 0.216
8.489LeuAsn: 8.489 ± 0.251
2.971LeuPro: 2.971 ± 1.418
5.518LeuGln: 5.518 ± 0.44
2.547LeuArg: 2.547 ± 1.243
5.942LeuSer: 5.942 ± 0.377
4.244LeuThr: 4.244 ± 0.796
7.216LeuVal: 7.216 ± 1.599
0.424LeuTrp: 0.424 ± 0.203
2.971LeuTyr: 2.971 ± 0.189
0.0LeuXaa: 0.0 ± 0.0
Met
2.547MetAla: 2.547 ± 0.601
0.849MetCys: 0.849 ± 0.405
0.849MetAsp: 0.849 ± 0.405
0.849MetGlu: 0.849 ± 0.405
1.698MetPhe: 1.698 ± 0.419
2.971MetGly: 2.971 ± 0.189
0.0MetHis: 0.0 ± 0.0
2.547MetIle: 2.547 ± 0.014
0.424MetLys: 0.424 ± 0.203
2.122MetLeu: 2.122 ± 0.216
0.0MetMet: 0.0 ± 0.0
0.849MetAsn: 0.849 ± 0.209
2.971MetPro: 2.971 ± 1.655
0.424MetGln: 0.424 ± 0.203
0.849MetArg: 0.849 ± 0.405
1.698MetSer: 1.698 ± 0.196
2.122MetThr: 2.122 ± 0.216
0.424MetVal: 0.424 ± 0.203
0.424MetTrp: 0.424 ± 0.203
1.698MetTyr: 1.698 ± 0.196
0.0MetXaa: 0.0 ± 0.0
Asn
5.518AsnAla: 5.518 ± 0.44
1.273AsnCys: 1.273 ± 0.608
1.273AsnAsp: 1.273 ± 0.007
1.273AsnGlu: 1.273 ± 0.608
4.244AsnPhe: 4.244 ± 1.047
4.669AsnGly: 4.669 ± 0.845
1.273AsnHis: 1.273 ± 0.608
2.971AsnIle: 2.971 ± 1.418
1.698AsnLys: 1.698 ± 0.196
5.942AsnLeu: 5.942 ± 0.992
0.424AsnMet: 0.424 ± 0.412
2.122AsnAsn: 2.122 ± 0.216
4.244AsnPro: 4.244 ± 1.662
0.424AsnGln: 0.424 ± 0.203
2.547AsnArg: 2.547 ± 1.243
2.547AsnSer: 2.547 ± 0.601
2.971AsnThr: 2.971 ± 0.426
3.82AsnVal: 3.82 ± 0.594
0.849AsnTrp: 0.849 ± 0.824
0.849AsnTyr: 0.849 ± 0.209
0.0AsnXaa: 0.0 ± 0.0
Pro
2.971ProAla: 2.971 ± 1.655
0.424ProCys: 0.424 ± 0.412
2.547ProAsp: 2.547 ± 0.628
2.122ProGlu: 2.122 ± 0.398
3.82ProPhe: 3.82 ± 1.208
2.547ProGly: 2.547 ± 0.014
1.698ProHis: 1.698 ± 0.196
2.547ProIle: 2.547 ± 0.601
2.971ProLys: 2.971 ± 0.803
4.244ProLeu: 4.244 ± 1.047
2.122ProMet: 2.122 ± 2.06
0.849ProAsn: 0.849 ± 0.405
2.122ProPro: 2.122 ± 0.398
2.971ProGln: 2.971 ± 0.803
1.698ProArg: 1.698 ± 0.196
5.093ProSer: 5.093 ± 2.486
2.122ProThr: 2.122 ± 0.831
3.396ProVal: 3.396 ± 0.223
0.849ProTrp: 0.849 ± 0.209
3.82ProTyr: 3.82 ± 0.635
0.0ProXaa: 0.0 ± 0.0
Gln
2.971GlnAla: 2.971 ± 0.803
0.424GlnCys: 0.424 ± 0.203
0.424GlnAsp: 0.424 ± 0.203
1.273GlnGlu: 1.273 ± 0.007
0.849GlnPhe: 0.849 ± 0.405
2.122GlnGly: 2.122 ± 0.398
0.0GlnHis: 0.0 ± 0.0
1.698GlnIle: 1.698 ± 1.648
1.698GlnLys: 1.698 ± 0.196
2.122GlnLeu: 2.122 ± 0.398
1.698GlnMet: 1.698 ± 0.196
0.849GlnAsn: 0.849 ± 0.405
0.849GlnPro: 0.849 ± 0.209
0.424GlnGln: 0.424 ± 0.412
1.273GlnArg: 1.273 ± 0.608
3.82GlnSer: 3.82 ± 0.635
2.547GlnThr: 2.547 ± 0.014
2.122GlnVal: 2.122 ± 0.398
0.0GlnTrp: 0.0 ± 0.0
0.424GlnTyr: 0.424 ± 0.412
0.0GlnXaa: 0.0 ± 0.0
Arg
2.547ArgAla: 2.547 ± 0.014
0.424ArgCys: 0.424 ± 0.203
3.396ArgAsp: 3.396 ± 0.391
2.547ArgGlu: 2.547 ± 1.215
1.698ArgPhe: 1.698 ± 0.419
2.971ArgGly: 2.971 ± 1.04
0.0ArgHis: 0.0 ± 0.0
1.698ArgIle: 1.698 ± 0.196
3.82ArgLys: 3.82 ± 0.594
3.396ArgLeu: 3.396 ± 0.838
1.698ArgMet: 1.698 ± 0.196
2.122ArgAsn: 2.122 ± 0.398
1.273ArgPro: 1.273 ± 0.007
0.0ArgGln: 0.0 ± 0.0
2.122ArgArg: 2.122 ± 0.398
3.396ArgSer: 3.396 ± 0.391
3.396ArgThr: 3.396 ± 0.223
3.396ArgVal: 3.396 ± 1.452
0.849ArgTrp: 0.849 ± 0.405
2.122ArgTyr: 2.122 ± 0.398
0.0ArgXaa: 0.0 ± 0.0
Ser
5.942SerAla: 5.942 ± 2.081
0.0SerCys: 0.0 ± 0.0
7.64SerAsp: 7.64 ± 3.114
1.698SerGlu: 1.698 ± 0.196
2.547SerPhe: 2.547 ± 0.628
3.82SerGly: 3.82 ± 0.635
0.424SerHis: 0.424 ± 0.412
4.669SerIle: 4.669 ± 0.23
4.669SerLys: 4.669 ± 0.384
6.791SerLeu: 6.791 ± 1.061
1.698SerMet: 1.698 ± 0.81
3.82SerAsn: 3.82 ± 0.594
2.122SerPro: 2.122 ± 0.831
2.971SerGln: 2.971 ± 0.426
5.093SerArg: 5.093 ± 1.201
6.367SerSer: 6.367 ± 1.264
2.971SerThr: 2.971 ± 0.189
5.093SerVal: 5.093 ± 1.871
2.971SerTrp: 2.971 ± 0.189
2.971SerTyr: 2.971 ± 0.803
0.0SerXaa: 0.0 ± 0.0
Thr
2.547ThrAla: 2.547 ± 0.014
1.273ThrCys: 1.273 ± 0.621
3.82ThrAsp: 3.82 ± 0.635
1.273ThrGlu: 1.273 ± 0.621
4.244ThrPhe: 4.244 ± 0.433
2.122ThrGly: 2.122 ± 0.216
0.849ThrHis: 0.849 ± 0.405
5.093ThrIle: 5.093 ± 0.028
5.518ThrLys: 5.518 ± 0.175
3.82ThrLeu: 3.82 ± 0.021
2.122ThrMet: 2.122 ± 0.398
3.82ThrAsn: 3.82 ± 1.864
5.518ThrPro: 5.518 ± 0.44
2.122ThrGln: 2.122 ± 0.831
2.971ThrArg: 2.971 ± 0.803
6.367ThrSer: 6.367 ± 3.107
6.791ThrThr: 6.791 ± 0.447
5.942ThrVal: 5.942 ± 0.377
0.849ThrTrp: 0.849 ± 0.209
2.971ThrTyr: 2.971 ± 0.426
0.0ThrXaa: 0.0 ± 0.0
Val
4.244ValAla: 4.244 ± 0.433
1.698ValCys: 1.698 ± 0.81
3.396ValAsp: 3.396 ± 0.391
4.244ValGlu: 4.244 ± 0.796
2.547ValPhe: 2.547 ± 1.215
2.547ValGly: 2.547 ± 0.628
0.849ValHis: 0.849 ± 0.405
3.82ValIle: 3.82 ± 0.635
4.669ValLys: 4.669 ± 0.384
5.093ValLeu: 5.093 ± 0.642
2.971ValMet: 2.971 ± 0.149
3.396ValAsn: 3.396 ± 1.62
4.244ValPro: 4.244 ± 0.182
2.122ValGln: 2.122 ± 1.013
4.244ValArg: 4.244 ± 0.433
5.942ValSer: 5.942 ± 0.237
5.093ValThr: 5.093 ± 1.257
2.971ValVal: 2.971 ± 1.418
1.273ValTrp: 1.273 ± 0.608
2.122ValTyr: 2.122 ± 0.831
0.0ValXaa: 0.0 ± 0.0
Trp
0.849TrpAla: 0.849 ± 0.405
0.424TrpCys: 0.424 ± 0.203
0.424TrpAsp: 0.424 ± 0.203
1.273TrpGlu: 1.273 ± 0.608
0.849TrpPhe: 0.849 ± 0.405
0.424TrpGly: 0.424 ± 0.203
0.424TrpHis: 0.424 ± 0.412
0.424TrpIle: 0.424 ± 0.203
0.849TrpLys: 0.849 ± 0.405
1.273TrpLeu: 1.273 ± 0.007
0.424TrpMet: 0.424 ± 0.412
1.273TrpAsn: 1.273 ± 0.007
0.849TrpPro: 0.849 ± 0.405
0.0TrpGln: 0.0 ± 0.0
0.849TrpArg: 0.849 ± 0.209
2.971TrpSer: 2.971 ± 0.189
1.273TrpThr: 1.273 ± 0.621
0.849TrpVal: 0.849 ± 0.405
0.0TrpTrp: 0.0 ± 0.0
0.424TrpTyr: 0.424 ± 0.203
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.122TyrAla: 2.122 ± 0.216
2.122TyrCys: 2.122 ± 1.445
2.122TyrAsp: 2.122 ± 0.398
0.0TyrGlu: 0.0 ± 0.0
3.396TyrPhe: 3.396 ± 1.62
3.396TyrGly: 3.396 ± 0.223
1.698TyrHis: 1.698 ± 1.648
1.273TyrIle: 1.273 ± 0.621
2.122TyrLys: 2.122 ± 0.398
3.396TyrLeu: 3.396 ± 1.006
1.273TyrMet: 1.273 ± 0.608
3.396TyrAsn: 3.396 ± 0.223
1.698TyrPro: 1.698 ± 0.419
0.424TyrGln: 0.424 ± 0.203
0.849TyrArg: 0.849 ± 0.209
1.273TyrSer: 1.273 ± 0.621
4.244TyrThr: 4.244 ± 0.433
3.396TyrVal: 3.396 ± 0.391
1.273TyrTrp: 1.273 ± 0.608
1.273TyrTyr: 1.273 ± 0.608
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2357 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski