Amino acid dipepetide frequency for Grapevine virus J

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.461AlaAla: 2.461 ± 1.334
1.231AlaCys: 1.231 ± 0.667
3.281AlaAsp: 3.281 ± 0.665
3.692AlaGlu: 3.692 ± 0.469
2.461AlaPhe: 2.461 ± 0.602
3.281AlaGly: 3.281 ± 1.263
0.0AlaHis: 0.0 ± 0.0
3.692AlaIle: 3.692 ± 2.761
5.742AlaLys: 5.742 ± 2.038
6.563AlaLeu: 6.563 ± 1.674
0.41AlaMet: 0.41 ± 0.847
1.641AlaAsn: 1.641 ± 0.889
0.82AlaPro: 0.82 ± 0.445
2.461AlaGln: 2.461 ± 2.207
2.461AlaArg: 2.461 ± 2.325
2.871AlaSer: 2.871 ± 1.069
3.281AlaThr: 3.281 ± 1.393
4.512AlaVal: 4.512 ± 3.012
0.41AlaTrp: 0.41 ± 0.222
2.461AlaTyr: 2.461 ± 0.617
0.0AlaXaa: 0.0 ± 0.0
Cys
1.231CysAla: 1.231 ± 0.682
0.0CysCys: 0.0 ± 0.0
1.231CysAsp: 1.231 ± 0.547
2.871CysGlu: 2.871 ± 1.114
1.231CysPhe: 1.231 ± 0.667
1.641CysGly: 1.641 ± 0.978
0.41CysHis: 0.41 ± 0.222
0.41CysIle: 0.41 ± 0.222
2.461CysLys: 2.461 ± 1.362
2.461CysLeu: 2.461 ± 1.439
0.41CysMet: 0.41 ± 0.222
0.41CysAsn: 0.41 ± 0.76
0.0CysPro: 0.0 ± 0.0
0.41CysGln: 0.41 ± 0.222
0.41CysArg: 0.41 ± 0.222
2.461CysSer: 2.461 ± 1.334
3.281CysThr: 3.281 ± 1.256
0.82CysVal: 0.82 ± 1.519
0.0CysTrp: 0.0 ± 0.0
0.41CysTyr: 0.41 ± 0.222
0.0CysXaa: 0.0 ± 0.0
Asp
4.512AspAla: 4.512 ± 1.208
2.051AspCys: 2.051 ± 0.865
4.512AspAsp: 4.512 ± 1.86
4.512AspGlu: 4.512 ± 0.891
3.281AspPhe: 3.281 ± 0.665
4.102AspGly: 4.102 ± 1.147
1.231AspHis: 1.231 ± 0.667
3.281AspIle: 3.281 ± 0.602
4.102AspLys: 4.102 ± 1.562
5.332AspLeu: 5.332 ± 1.799
2.461AspMet: 2.461 ± 0.79
1.231AspAsn: 1.231 ± 0.547
2.871AspPro: 2.871 ± 1.345
4.102AspGln: 4.102 ± 1.774
4.102AspArg: 4.102 ± 1.655
4.102AspSer: 4.102 ± 0.581
2.051AspThr: 2.051 ± 0.645
4.512AspVal: 4.512 ± 1.786
2.051AspTrp: 2.051 ± 1.112
3.281AspTyr: 3.281 ± 0.656
0.0AspXaa: 0.0 ± 0.0
Glu
4.512GluAla: 4.512 ± 2.031
1.231GluCys: 1.231 ± 0.667
4.512GluAsp: 4.512 ± 1.627
6.973GluGlu: 6.973 ± 1.787
2.051GluPhe: 2.051 ± 0.865
6.153GluGly: 6.153 ± 1.843
1.641GluHis: 1.641 ± 0.889
3.281GluIle: 3.281 ± 0.602
5.332GluLys: 5.332 ± 2.264
5.332GluLeu: 5.332 ± 1.17
2.051GluMet: 2.051 ± 0.806
1.231GluAsn: 1.231 ± 0.547
3.281GluPro: 3.281 ± 1.51
1.641GluGln: 1.641 ± 0.939
4.102GluArg: 4.102 ± 0.948
5.332GluSer: 5.332 ± 0.828
3.281GluThr: 3.281 ± 1.248
7.383GluVal: 7.383 ± 1.754
0.82GluTrp: 0.82 ± 0.445
4.102GluTyr: 4.102 ± 0.581
0.0GluXaa: 0.0 ± 0.0
Phe
3.281PheAla: 3.281 ± 1.692
1.231PheCys: 1.231 ± 0.547
2.461PheAsp: 2.461 ± 0.908
0.82PheGlu: 0.82 ± 0.445
1.641PhePhe: 1.641 ± 0.889
2.051PheGly: 2.051 ± 0.778
1.641PheHis: 1.641 ± 0.555
2.051PheIle: 2.051 ± 0.69
3.692PheLys: 3.692 ± 1.183
4.922PheLeu: 4.922 ± 1.582
0.41PheMet: 0.41 ± 0.222
2.871PheAsn: 2.871 ± 0.777
2.051PhePro: 2.051 ± 1.151
0.41PheGln: 0.41 ± 0.844
2.461PheArg: 2.461 ± 0.908
5.332PheSer: 5.332 ± 1.749
0.82PheThr: 0.82 ± 0.445
1.641PheVal: 1.641 ± 1.134
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.461GlyAla: 2.461 ± 1.52
0.82GlyCys: 0.82 ± 0.623
6.563GlyAsp: 6.563 ± 1.933
5.332GlyGlu: 5.332 ± 2.371
2.461GlyPhe: 2.461 ± 0.79
2.051GlyGly: 2.051 ± 0.69
0.41GlyHis: 0.41 ± 0.222
2.871GlyIle: 2.871 ± 0.765
2.871GlyLys: 2.871 ± 1.145
8.203GlyLeu: 8.203 ± 5.148
1.231GlyMet: 1.231 ± 0.681
2.461GlyAsn: 2.461 ± 0.908
2.871GlyPro: 2.871 ± 1.494
2.051GlyGln: 2.051 ± 0.784
4.922GlyArg: 4.922 ± 3.832
5.742GlySer: 5.742 ± 2.206
3.281GlyThr: 3.281 ± 0.602
1.641GlyVal: 1.641 ± 0.696
0.82GlyTrp: 0.82 ± 0.445
4.512GlyTyr: 4.512 ± 1.308
0.0GlyXaa: 0.0 ± 0.0
His
2.051HisAla: 2.051 ± 0.645
0.41HisCys: 0.41 ± 0.222
2.051HisAsp: 2.051 ± 1.151
1.641HisGlu: 1.641 ± 0.696
0.41HisPhe: 0.41 ± 0.222
1.231HisGly: 1.231 ± 1.372
0.82HisHis: 0.82 ± 0.445
0.41HisIle: 0.41 ± 0.222
2.051HisLys: 2.051 ± 0.645
1.231HisLeu: 1.231 ± 0.667
0.41HisMet: 0.41 ± 0.222
0.41HisAsn: 0.41 ± 0.839
2.461HisPro: 2.461 ± 0.798
0.41HisGln: 0.41 ± 0.222
1.641HisArg: 1.641 ± 0.555
2.461HisSer: 2.461 ± 0.908
0.41HisThr: 0.41 ± 0.222
1.231HisVal: 1.231 ± 1.372
0.41HisTrp: 0.41 ± 0.222
0.41HisTyr: 0.41 ± 0.222
0.0HisXaa: 0.0 ± 0.0
Ile
4.102IleAla: 4.102 ± 1.356
0.41IleCys: 0.41 ± 0.222
3.692IleAsp: 3.692 ± 1.165
2.871IleGlu: 2.871 ± 1.125
0.82IlePhe: 0.82 ± 0.445
2.461IleGly: 2.461 ± 1.213
2.051IleHis: 2.051 ± 0.865
1.641IleIle: 1.641 ± 0.889
3.692IleLys: 3.692 ± 0.788
5.332IleLeu: 5.332 ± 1.536
1.231IleMet: 1.231 ± 0.85
2.871IleAsn: 2.871 ± 0.765
0.82IlePro: 0.82 ± 0.445
1.641IleGln: 1.641 ± 0.889
1.231IleArg: 1.231 ± 0.681
6.153IleSer: 6.153 ± 2.656
2.461IleThr: 2.461 ± 0.915
2.871IleVal: 2.871 ± 0.964
0.82IleTrp: 0.82 ± 0.735
2.051IleTyr: 2.051 ± 0.827
0.0IleXaa: 0.0 ± 0.0
Lys
4.512LysAla: 4.512 ± 0.972
2.871LysCys: 2.871 ± 0.791
5.742LysAsp: 5.742 ± 2.159
6.153LysGlu: 6.153 ± 0.616
1.231LysPhe: 1.231 ± 0.667
3.692LysGly: 3.692 ± 0.947
0.82LysHis: 0.82 ± 0.445
3.281LysIle: 3.281 ± 0.718
4.512LysLys: 4.512 ± 1.181
7.793LysLeu: 7.793 ± 1.729
1.641LysMet: 1.641 ± 0.696
6.153LysAsn: 6.153 ± 2.692
2.461LysPro: 2.461 ± 0.908
1.641LysGln: 1.641 ± 0.889
3.692LysArg: 3.692 ± 1.4
5.742LysSer: 5.742 ± 1.404
4.102LysThr: 4.102 ± 1.311
5.332LysVal: 5.332 ± 0.8
0.41LysTrp: 0.41 ± 0.222
0.41LysTyr: 0.41 ± 0.222
0.0LysXaa: 0.0 ± 0.0
Leu
6.153LeuAla: 6.153 ± 2.089
2.871LeuCys: 2.871 ± 1.365
8.203LeuAsp: 8.203 ± 0.928
6.153LeuGlu: 6.153 ± 2.023
5.332LeuPhe: 5.332 ± 1.97
7.793LeuGly: 7.793 ± 3.98
1.641LeuHis: 1.641 ± 0.555
6.153LeuIle: 6.153 ± 1.417
9.434LeuLys: 9.434 ± 3.758
6.563LeuLeu: 6.563 ± 2.012
2.461LeuMet: 2.461 ± 1.291
5.332LeuAsn: 5.332 ± 2.201
2.461LeuPro: 2.461 ± 0.915
1.641LeuGln: 1.641 ± 0.846
9.024LeuArg: 9.024 ± 3.068
10.664LeuSer: 10.664 ± 4.437
3.692LeuThr: 3.692 ± 1.179
5.332LeuVal: 5.332 ± 1.899
0.82LeuTrp: 0.82 ± 0.731
2.461LeuTyr: 2.461 ± 1.334
0.0LeuXaa: 0.0 ± 0.0
Met
1.231MetAla: 1.231 ± 0.547
0.82MetCys: 0.82 ± 0.736
1.231MetAsp: 1.231 ± 0.681
2.051MetGlu: 2.051 ± 2.339
1.231MetPhe: 1.231 ± 1.015
2.051MetGly: 2.051 ± 0.706
1.641MetHis: 1.641 ± 1.435
0.82MetIle: 0.82 ± 0.445
0.82MetLys: 0.82 ± 0.445
2.871MetLeu: 2.871 ± 1.069
0.41MetMet: 0.41 ± 0.222
0.82MetAsn: 0.82 ± 0.731
1.231MetPro: 1.231 ± 0.547
0.41MetGln: 0.41 ± 0.222
2.051MetArg: 2.051 ± 1.112
2.051MetSer: 2.051 ± 1.176
0.41MetThr: 0.41 ± 0.847
0.41MetVal: 0.41 ± 0.222
0.0MetTrp: 0.0 ± 0.0
1.231MetTyr: 1.231 ± 0.681
0.0MetXaa: 0.0 ± 0.0
Asn
1.231AsnAla: 1.231 ± 0.681
1.231AsnCys: 1.231 ± 0.547
0.82AsnAsp: 0.82 ± 0.445
4.922AsnGlu: 4.922 ± 1.432
2.051AsnPhe: 2.051 ± 1.112
1.231AsnGly: 1.231 ± 0.547
0.82AsnHis: 0.82 ± 0.445
2.461AsnIle: 2.461 ± 0.84
4.102AsnLys: 4.102 ± 1.797
6.153AsnLeu: 6.153 ± 1.201
2.051AsnMet: 2.051 ± 1.151
2.051AsnAsn: 2.051 ± 1.408
0.41AsnPro: 0.41 ± 0.839
0.41AsnGln: 0.41 ± 0.222
1.641AsnArg: 1.641 ± 0.889
3.692AsnSer: 3.692 ± 2.001
2.051AsnThr: 2.051 ± 0.69
2.871AsnVal: 2.871 ± 1.001
0.41AsnTrp: 0.41 ± 0.222
2.871AsnTyr: 2.871 ± 1.082
0.0AsnXaa: 0.0 ± 0.0
Pro
1.231ProAla: 1.231 ± 0.667
0.41ProCys: 0.41 ± 0.222
1.641ProAsp: 1.641 ± 0.702
3.281ProGlu: 3.281 ± 1.248
0.82ProPhe: 0.82 ± 1.202
2.461ProGly: 2.461 ± 0.602
0.82ProHis: 0.82 ± 0.623
2.051ProIle: 2.051 ± 1.88
2.051ProLys: 2.051 ± 2.339
3.281ProLeu: 3.281 ± 1.248
0.82ProMet: 0.82 ± 0.623
2.461ProAsn: 2.461 ± 0.79
0.41ProPro: 0.41 ± 0.222
1.641ProGln: 1.641 ± 0.696
0.82ProArg: 0.82 ± 0.623
1.641ProSer: 1.641 ± 0.702
1.231ProThr: 1.231 ± 0.667
2.871ProVal: 2.871 ± 1.966
0.0ProTrp: 0.0 ± 0.0
1.231ProTyr: 1.231 ± 0.667
0.0ProXaa: 0.0 ± 0.0
Gln
1.231GlnAla: 1.231 ± 1.571
2.051GlnCys: 2.051 ± 0.645
2.461GlnAsp: 2.461 ± 0.79
3.692GlnGlu: 3.692 ± 1.278
0.0GlnPhe: 0.0 ± 0.0
2.461GlnGly: 2.461 ± 0.972
0.0GlnHis: 0.0 ± 0.0
1.641GlnIle: 1.641 ± 0.555
0.82GlnLys: 0.82 ± 0.445
4.512GlnLeu: 4.512 ± 1.457
1.231GlnMet: 1.231 ± 1.936
0.0GlnAsn: 0.0 ± 0.0
0.82GlnPro: 0.82 ± 0.445
0.41GlnGln: 0.41 ± 0.222
2.051GlnArg: 2.051 ± 0.898
2.051GlnSer: 2.051 ± 0.706
2.461GlnThr: 2.461 ± 0.602
1.231GlnVal: 1.231 ± 0.681
0.0GlnTrp: 0.0 ± 0.0
0.41GlnTyr: 0.41 ± 0.222
0.0GlnXaa: 0.0 ± 0.0
Arg
2.871ArgAla: 2.871 ± 1.493
1.231ArgCys: 1.231 ± 0.682
3.281ArgAsp: 3.281 ± 1.256
2.871ArgGlu: 2.871 ± 1.145
4.102ArgPhe: 4.102 ± 1.561
4.922ArgGly: 4.922 ± 1.95
1.641ArgHis: 1.641 ± 0.889
2.461ArgIle: 2.461 ± 0.972
4.102ArgLys: 4.102 ± 2.042
8.614ArgLeu: 8.614 ± 0.738
2.461ArgMet: 2.461 ± 0.953
1.641ArgAsn: 1.641 ± 0.555
1.641ArgPro: 1.641 ± 0.696
1.641ArgGln: 1.641 ± 1.635
2.871ArgArg: 2.871 ± 3.895
3.281ArgSer: 3.281 ± 0.828
3.281ArgThr: 3.281 ± 1.239
4.922ArgVal: 4.922 ± 1.582
1.231ArgTrp: 1.231 ± 1.125
2.051ArgTyr: 2.051 ± 0.784
0.0ArgXaa: 0.0 ± 0.0
Ser
4.102SerAla: 4.102 ± 1.291
1.231SerCys: 1.231 ± 0.682
4.102SerAsp: 4.102 ± 1.368
6.973SerGlu: 6.973 ± 3.124
4.512SerPhe: 4.512 ± 1.416
8.203SerGly: 8.203 ± 2.386
3.281SerHis: 3.281 ± 1.111
5.332SerIle: 5.332 ± 2.201
4.922SerLys: 4.922 ± 1.815
4.102SerLeu: 4.102 ± 1.106
0.82SerMet: 0.82 ± 0.445
1.641SerAsn: 1.641 ± 1.004
2.051SerPro: 2.051 ± 0.784
2.871SerGln: 2.871 ± 1.334
8.203SerArg: 8.203 ± 4.203
4.922SerSer: 4.922 ± 3.13
2.871SerThr: 2.871 ± 0.589
6.153SerVal: 6.153 ± 0.838
0.41SerTrp: 0.41 ± 0.222
3.281SerTyr: 3.281 ± 1.263
0.0SerXaa: 0.0 ± 0.0
Thr
0.82ThrAla: 0.82 ± 0.445
0.82ThrCys: 0.82 ± 0.445
2.051ThrAsp: 2.051 ± 0.787
2.051ThrGlu: 2.051 ± 1.176
2.461ThrPhe: 2.461 ± 1.334
1.641ThrGly: 1.641 ± 0.889
1.231ThrHis: 1.231 ± 0.547
3.281ThrIle: 3.281 ± 1.111
2.461ThrLys: 2.461 ± 0.908
6.563ThrLeu: 6.563 ± 3.363
0.82ThrMet: 0.82 ± 0.491
2.051ThrAsn: 2.051 ± 0.784
2.051ThrPro: 2.051 ± 0.787
1.231ThrGln: 1.231 ± 0.667
3.692ThrArg: 3.692 ± 1.511
3.692ThrSer: 3.692 ± 0.788
1.231ThrThr: 1.231 ± 0.667
3.281ThrVal: 3.281 ± 0.893
1.641ThrTrp: 1.641 ± 1.134
1.641ThrTyr: 1.641 ± 0.889
0.0ThrXaa: 0.0 ± 0.0
Val
3.281ValAla: 3.281 ± 0.844
0.82ValCys: 0.82 ± 1.404
6.153ValAsp: 6.153 ± 2.837
2.871ValGlu: 2.871 ± 1.687
2.461ValPhe: 2.461 ± 1.865
3.692ValGly: 3.692 ± 2.322
2.051ValHis: 2.051 ± 1.456
2.461ValIle: 2.461 ± 1.334
6.153ValLys: 6.153 ± 1.45
6.563ValLeu: 6.563 ± 1.771
1.641ValMet: 1.641 ± 0.846
4.922ValAsn: 4.922 ± 2.101
0.82ValPro: 0.82 ± 0.623
3.281ValGln: 3.281 ± 0.602
2.871ValArg: 2.871 ± 1.001
3.692ValSer: 3.692 ± 0.996
2.461ValThr: 2.461 ± 1.334
6.563ValVal: 6.563 ± 2.063
0.41ValTrp: 0.41 ± 0.222
4.102ValTyr: 4.102 ± 1.165
0.0ValXaa: 0.0 ± 0.0
Trp
0.41TrpAla: 0.41 ± 0.222
0.82TrpCys: 0.82 ± 0.731
0.82TrpAsp: 0.82 ± 0.445
0.82TrpGlu: 0.82 ± 0.445
0.41TrpPhe: 0.41 ± 0.76
1.231TrpGly: 1.231 ± 1.257
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.82TrpLys: 0.82 ± 0.445
1.641TrpLeu: 1.641 ± 0.889
0.41TrpMet: 0.41 ± 0.222
0.41TrpAsn: 0.41 ± 0.222
0.41TrpPro: 0.41 ± 0.222
0.82TrpGln: 0.82 ± 0.735
0.41TrpArg: 0.41 ± 0.222
0.41TrpSer: 0.41 ± 0.222
0.82TrpThr: 0.82 ± 0.445
0.82TrpVal: 0.82 ± 0.731
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.051TyrAla: 2.051 ± 0.787
0.0TyrCys: 0.0 ± 0.0
2.871TyrAsp: 2.871 ± 0.868
3.692TyrGlu: 3.692 ± 1.179
0.82TyrPhe: 0.82 ± 0.623
1.231TyrGly: 1.231 ± 0.681
0.41TyrHis: 0.41 ± 0.222
2.051TyrIle: 2.051 ± 0.778
2.051TyrLys: 2.051 ± 0.865
6.153TyrLeu: 6.153 ± 2.058
0.0TyrMet: 0.0 ± 0.0
2.871TyrAsn: 2.871 ± 1.082
1.231TyrPro: 1.231 ± 1.001
0.41TyrGln: 0.41 ± 0.76
2.461TyrArg: 2.461 ± 1.334
3.692TyrSer: 3.692 ± 0.788
1.231TyrThr: 1.231 ± 0.667
2.871TyrVal: 2.871 ± 1.557
0.82TyrTrp: 0.82 ± 0.445
0.82TyrTyr: 0.82 ± 0.445
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2439 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski