Amino acid dipepetide frequency for Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.537AlaAla: 10.537 ± 0.266	0.965AlaCys: 0.965 ± 0.037	4.966AlaAsp: 4.966 ± 0.118	6.312AlaGlu: 6.312 ± 0.185	3.199AlaPhe: 3.199 ± 0.053	7.543AlaGly: 7.543 ± 0.165	2.501AlaHis: 2.501 ± 0.06	5.039AlaIle: 5.039 ± 0.072	3.934AlaLys: 3.934 ± 0.07	12.146AlaLeu: 12.146 ± 0.174	3.201AlaMet: 3.201 ± 0.062	2.967AlaAsn: 2.967 ± 0.089	4.172AlaPro: 4.172 ± 0.071	5.814AlaGln: 5.814 ± 0.118	5.364AlaArg: 5.364 ± 0.13	5.182AlaSer: 5.182 ± 0.13	5.16AlaThr: 5.16 ± 0.145	6.693AlaVal: 6.693 ± 0.073	1.395AlaTrp: 1.395 ± 0.035	2.349AlaTyr: 2.349 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.8CysAla: 0.8 ± 0.025	0.148CysCys: 0.148 ± 0.011	0.523CysAsp: 0.523 ± 0.022	0.477CysGlu: 0.477 ± 0.023	0.36CysPhe: 0.36 ± 0.017	0.907CysGly: 0.907 ± 0.033	0.453CysHis: 0.453 ± 0.023	0.386CysIle: 0.386 ± 0.02	0.341CysLys: 0.341 ± 0.017	0.806CysLeu: 0.806 ± 0.028	0.25CysMet: 0.25 ± 0.014	0.294CysAsn: 0.294 ± 0.016	0.545CysPro: 0.545 ± 0.023	0.482CysGln: 0.482 ± 0.024	0.695CysArg: 0.695 ± 0.026	0.534CysSer: 0.534 ± 0.022	0.426CysThr: 0.426 ± 0.022	0.612CysVal: 0.612 ± 0.025	0.145CysTrp: 0.145 ± 0.01	0.29CysTyr: 0.29 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.675AspAla: 5.675 ± 0.145	0.415AspCys: 0.415 ± 0.02	2.726AspAsp: 2.726 ± 0.072	3.463AspGlu: 3.463 ± 0.062	2.062AspPhe: 2.062 ± 0.082	4.712AspGly: 4.712 ± 0.215	1.471AspHis: 1.471 ± 0.037	2.427AspIle: 2.427 ± 0.05	1.965AspLys: 1.965 ± 0.053	6.171AspLeu: 6.171 ± 0.149	1.314AspMet: 1.314 ± 0.04	1.609AspAsn: 1.609 ± 0.061	2.87AspPro: 2.87 ± 0.054	2.227AspGln: 2.227 ± 0.062	2.981AspArg: 2.981 ± 0.06	2.529AspSer: 2.529 ± 0.108	2.587AspThr: 2.587 ± 0.112	3.359AspVal: 3.359 ± 0.084	0.693AspTrp: 0.693 ± 0.026	1.485AspTyr: 1.485 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	6.937GluAla: 6.937 ± 0.139	0.402GluCys: 0.402 ± 0.017	2.824GluAsp: 2.824 ± 0.066	4.189GluGlu: 4.189 ± 0.227	1.462GluPhe: 1.462 ± 0.037	4.506GluGly: 4.506 ± 0.071	1.499GluHis: 1.499 ± 0.04	3.496GluIle: 3.496 ± 0.058	2.882GluLys: 2.882 ± 0.065	5.905GluLeu: 5.905 ± 0.093	1.869GluMet: 1.869 ± 0.043	1.91GluAsn: 1.91 ± 0.044	2.65GluPro: 2.65 ± 0.073	4.007GluGln: 4.007 ± 0.098	4.273GluArg: 4.273 ± 0.093	3.601GluSer: 3.601 ± 0.061	2.932GluThr: 2.932 ± 0.051	4.349GluVal: 4.349 ± 0.084	0.652GluTrp: 0.652 ± 0.027	1.011GluTyr: 1.011 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	3.112PheAla: 3.112 ± 0.06	0.407PheCys: 0.407 ± 0.02	2.159PheAsp: 2.159 ± 0.075	2.082PheGlu: 2.082 ± 0.037	1.39PhePhe: 1.39 ± 0.039	2.633PheGly: 2.633 ± 0.055	0.837PheHis: 0.837 ± 0.029	1.847PheIle: 1.847 ± 0.05	1.461PheLys: 1.461 ± 0.035	3.341PheLeu: 3.341 ± 0.069	0.959PheMet: 0.959 ± 0.032	1.423PheAsn: 1.423 ± 0.04	1.349PhePro: 1.349 ± 0.042	1.414PheGln: 1.414 ± 0.034	1.815PheArg: 1.815 ± 0.049	2.515PheSer: 2.515 ± 0.1	2.156PheThr: 2.156 ± 0.069	2.207PheVal: 2.207 ± 0.05	0.458PheTrp: 0.458 ± 0.016	1.03PheTyr: 1.03 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	6.817GlyAla: 6.817 ± 0.17	0.932GlyCys: 0.932 ± 0.033	4.341GlyAsp: 4.341 ± 0.171	4.85GlyGlu: 4.85 ± 0.076	3.027GlyPhe: 3.027 ± 0.061	6.485GlyGly: 6.485 ± 0.182	1.981GlyHis: 1.981 ± 0.044	4.101GlyIle: 4.101 ± 0.068	3.275GlyLys: 3.275 ± 0.075	8.178GlyLeu: 8.178 ± 0.116	2.577GlyMet: 2.577 ± 0.057	2.32GlyAsn: 2.32 ± 0.079	2.325GlyPro: 2.325 ± 0.053	3.494GlyGln: 3.494 ± 0.062	4.444GlyArg: 4.444 ± 0.076	4.777GlySer: 4.777 ± 0.179	3.976GlyThr: 3.976 ± 0.155	6.436GlyVal: 6.436 ± 0.112	1.392GlyTrp: 1.392 ± 0.039	2.444GlyTyr: 2.444 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.613HisAla: 2.613 ± 0.059	0.341HisCys: 0.341 ± 0.018	1.258HisAsp: 1.258 ± 0.038	1.394HisGlu: 1.394 ± 0.036	1.139HisPhe: 1.139 ± 0.033	2.242HisGly: 2.242 ± 0.051	0.956HisHis: 0.956 ± 0.038	1.232HisIle: 1.232 ± 0.03	0.923HisLys: 0.923 ± 0.03	2.909HisLeu: 2.909 ± 0.065	0.632HisMet: 0.632 ± 0.025	0.825HisAsn: 0.825 ± 0.028	1.66HisPro: 1.66 ± 0.044	1.214HisGln: 1.214 ± 0.035	1.496HisArg: 1.496 ± 0.043	1.315HisSer: 1.315 ± 0.033	1.358HisThr: 1.358 ± 0.033	1.525HisVal: 1.525 ± 0.034	0.45HisTrp: 0.45 ± 0.02	0.864HisTyr: 0.864 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	4.792IleAla: 4.792 ± 0.092	0.502IleCys: 0.502 ± 0.023	2.763IleAsp: 2.763 ± 0.068	3.19IleGlu: 3.19 ± 0.053	1.708IlePhe: 1.708 ± 0.045	3.494IleGly: 3.494 ± 0.059	1.493IleHis: 1.493 ± 0.037	2.49IleIle: 2.49 ± 0.057	2.147IleLys: 2.147 ± 0.049	5.002IleLeu: 5.002 ± 0.069	1.073IleMet: 1.073 ± 0.033	1.951IleAsn: 1.951 ± 0.042	2.604IlePro: 2.604 ± 0.059	2.229IleGln: 2.229 ± 0.045	3.114IleArg: 3.114 ± 0.061	3.16IleSer: 3.16 ± 0.063	3.511IleThr: 3.511 ± 0.115	2.872IleVal: 2.872 ± 0.053	0.56IleTrp: 0.56 ± 0.022	1.254IleTyr: 1.254 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	3.785LysAla: 3.785 ± 0.089	0.23LysCys: 0.23 ± 0.016	2.025LysAsp: 2.025 ± 0.062	2.521LysGlu: 2.521 ± 0.063	1.013LysPhe: 1.013 ± 0.033	3.109LysGly: 3.109 ± 0.061	0.85LysHis: 0.85 ± 0.027	1.914LysIle: 1.914 ± 0.044	2.021LysLys: 2.021 ± 0.063	3.878LysLeu: 3.878 ± 0.08	1.032LysMet: 1.032 ± 0.03	1.268LysAsn: 1.268 ± 0.036	2.178LysPro: 2.178 ± 0.048	2.261LysGln: 2.261 ± 0.055	2.958LysArg: 2.958 ± 0.066	2.221LysSer: 2.221 ± 0.057	1.883LysThr: 1.883 ± 0.042	2.739LysVal: 2.739 ± 0.053	0.451LysTrp: 0.451 ± 0.024	0.687LysTyr: 0.687 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	11.045LeuAla: 11.045 ± 0.148	1.075LeuCys: 1.075 ± 0.033	6.092LeuAsp: 6.092 ± 0.102	7.117LeuGlu: 7.117 ± 0.102	4.251LeuPhe: 4.251 ± 0.084	7.784LeuGly: 7.784 ± 0.099	2.769LeuHis: 2.769 ± 0.064	4.901LeuIle: 4.901 ± 0.083	4.498LeuLys: 4.498 ± 0.084	12.233LeuLeu: 12.233 ± 0.195	2.755LeuMet: 2.755 ± 0.056	3.635LeuAsn: 3.635 ± 0.059	5.495LeuPro: 5.495 ± 0.077	5.285LeuGln: 5.285 ± 0.088	6.065LeuArg: 6.065 ± 0.097	7.341LeuSer: 7.341 ± 0.143	6.217LeuThr: 6.217 ± 0.105	7.178LeuVal: 7.178 ± 0.094	1.324LeuTrp: 1.324 ± 0.039	2.69LeuTyr: 2.69 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	3.527MetAla: 3.527 ± 0.075	0.167MetCys: 0.167 ± 0.011	1.818MetAsp: 1.818 ± 0.04	1.772MetGlu: 1.772 ± 0.04	0.691MetPhe: 0.691 ± 0.023	2.495MetGly: 2.495 ± 0.046	0.608MetHis: 0.608 ± 0.024	1.193MetIle: 1.193 ± 0.031	0.938MetLys: 0.938 ± 0.031	2.848MetLeu: 2.848 ± 0.055	0.707MetMet: 0.707 ± 0.027	0.864MetAsn: 0.864 ± 0.027	1.453MetPro: 1.453 ± 0.044	1.539MetGln: 1.539 ± 0.042	1.687MetArg: 1.687 ± 0.041	1.686MetSer: 1.686 ± 0.039	1.399MetThr: 1.399 ± 0.036	2.379MetVal: 2.379 ± 0.046	0.232MetTrp: 0.232 ± 0.013	0.314MetTyr: 0.314 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.828AsnAla: 2.828 ± 0.061	0.281AsnCys: 0.281 ± 0.016	1.587AsnAsp: 1.587 ± 0.067	1.433AsnGlu: 1.433 ± 0.036	0.997AsnPhe: 0.997 ± 0.036	2.615AsnGly: 2.615 ± 0.102	0.992AsnHis: 0.992 ± 0.026	1.584AsnIle: 1.584 ± 0.042	1.137AsnLys: 1.137 ± 0.034	3.528AsnLeu: 3.528 ± 0.072	0.88AsnMet: 0.88 ± 0.03	1.022AsnAsn: 1.022 ± 0.035	2.156AsnPro: 2.156 ± 0.047	1.6AsnGln: 1.6 ± 0.04	2.385AsnArg: 2.385 ± 0.055	1.836AsnSer: 1.836 ± 0.081	1.633AsnThr: 1.633 ± 0.076	1.898AsnVal: 1.898 ± 0.063	0.444AsnTrp: 0.444 ± 0.018	0.833AsnTyr: 0.833 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	4.335ProAla: 4.335 ± 0.079	0.418ProCys: 0.418 ± 0.018	2.66ProAsp: 2.66 ± 0.058	3.337ProGlu: 3.337 ± 0.077	1.811ProPhe: 1.811 ± 0.042	3.259ProGly: 3.259 ± 0.07	1.402ProHis: 1.402 ± 0.041	2.438ProIle: 2.438 ± 0.055	1.731ProLys: 1.731 ± 0.046	5.298ProLeu: 5.298 ± 0.09	1.53ProMet: 1.53 ± 0.04	1.59ProAsn: 1.59 ± 0.04	2.65ProPro: 2.65 ± 0.077	2.368ProGln: 2.368 ± 0.053	2.196ProArg: 2.196 ± 0.061	2.641ProSer: 2.641 ± 0.061	2.532ProThr: 2.532 ± 0.051	3.589ProVal: 3.589 ± 0.059	0.797ProTrp: 0.797 ± 0.032	1.327ProTyr: 1.327 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	6.08GlnAla: 6.08 ± 0.116	0.391GlnCys: 0.391 ± 0.019	2.105GlnAsp: 2.105 ± 0.052	3.009GlnGlu: 3.009 ± 0.065	1.377GlnPhe: 1.377 ± 0.034	4.159GlnGly: 4.159 ± 0.067	1.306GlnHis: 1.306 ± 0.039	2.425GlnIle: 2.425 ± 0.043	1.719GlnLys: 1.719 ± 0.051	5.611GlnLeu: 5.611 ± 0.09	1.32GlnMet: 1.32 ± 0.034	1.298GlnAsn: 1.298 ± 0.032	2.64GlnPro: 2.64 ± 0.06	3.917GlnGln: 3.917 ± 0.101	3.81GlnArg: 3.81 ± 0.089	2.77GlnSer: 2.77 ± 0.058	2.279GlnThr: 2.279 ± 0.05	3.667GlnVal: 3.667 ± 0.058	0.873GlnTrp: 0.873 ± 0.03	0.744GlnTyr: 0.744 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	5.056ArgAla: 5.056 ± 0.084	0.683ArgCys: 0.683 ± 0.028	2.892ArgAsp: 2.892 ± 0.062	3.58ArgGlu: 3.58 ± 0.081	2.714ArgPhe: 2.714 ± 0.057	3.86ArgGly: 3.86 ± 0.079	1.755ArgHis: 1.755 ± 0.046	3.466ArgIle: 3.466 ± 0.089	2.265ArgLys: 2.265 ± 0.062	7.262ArgLeu: 7.262 ± 0.126	1.916ArgMet: 1.916 ± 0.044	1.769ArgAsn: 1.769 ± 0.043	2.523ArgPro: 2.523 ± 0.061	3.257ArgGln: 3.257 ± 0.069	3.675ArgArg: 3.675 ± 0.079	3.123ArgSer: 3.123 ± 0.061	2.671ArgThr: 2.671 ± 0.052	4.389ArgVal: 4.389 ± 0.083	1.02ArgTrp: 1.02 ± 0.03	2.009ArgTyr: 2.009 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	5.461SerAla: 5.461 ± 0.142	0.566SerCys: 0.566 ± 0.022	2.951SerAsp: 2.951 ± 0.096	3.047SerGlu: 3.047 ± 0.069	2.192SerPhe: 2.192 ± 0.072	5.415SerGly: 5.415 ± 0.21	1.613SerHis: 1.613 ± 0.04	2.978SerIle: 2.978 ± 0.075	2.107SerLys: 2.107 ± 0.043	5.983SerLeu: 5.983 ± 0.094	1.797SerMet: 1.797 ± 0.039	1.843SerAsn: 1.843 ± 0.067	2.557SerPro: 2.557 ± 0.05	2.604SerGln: 2.604 ± 0.049	3.417SerArg: 3.417 ± 0.063	3.653SerSer: 3.653 ± 0.109	2.967SerThr: 2.967 ± 0.072	3.995SerVal: 3.995 ± 0.112	0.885SerTrp: 0.885 ± 0.035	1.768SerTyr: 1.768 ± 0.13	0.0SerXaa: 0.0 ± 0.0
Thr	5.188ThrAla: 5.188 ± 0.114	0.43ThrCys: 0.43 ± 0.021	2.66ThrAsp: 2.66 ± 0.146	2.558ThrGlu: 2.558 ± 0.052	1.853ThrPhe: 1.853 ± 0.065	4.359ThrGly: 4.359 ± 0.153	1.299ThrHis: 1.299 ± 0.035	2.899ThrIle: 2.899 ± 0.088	1.576ThrLys: 1.576 ± 0.037	7.111ThrLeu: 7.111 ± 0.149	1.354ThrMet: 1.354 ± 0.055	1.548ThrAsn: 1.548 ± 0.08	3.522ThrPro: 3.522 ± 0.066	2.34ThrGln: 2.34 ± 0.049	2.655ThrArg: 2.655 ± 0.058	2.724ThrSer: 2.724 ± 0.098	3.156ThrThr: 3.156 ± 0.111	3.871ThrVal: 3.871 ± 0.116	0.603ThrTrp: 0.603 ± 0.031	1.236ThrTyr: 1.236 ± 0.067	0.0ThrXaa: 0.0 ± 0.0
Val	7.455ValAla: 7.455 ± 0.106	0.677ValCys: 0.677 ± 0.027	4.279ValAsp: 4.279 ± 0.102	5.047ValGlu: 5.047 ± 0.074	1.94ValPhe: 1.94 ± 0.046	5.423ValGly: 5.423 ± 0.093	1.404ValHis: 1.404 ± 0.038	3.467ValIle: 3.467 ± 0.047	2.767ValLys: 2.767 ± 0.057	6.888ValLeu: 6.888 ± 0.082	2.109ValMet: 2.109 ± 0.046	2.315ValAsn: 2.315 ± 0.071	2.788ValPro: 2.788 ± 0.064	3.096ValGln: 3.096 ± 0.065	4.086ValArg: 4.086 ± 0.075	3.926ValSer: 3.926 ± 0.089	4.353ValThr: 4.353 ± 0.191	6.294ValVal: 6.294 ± 0.102	0.851ValTrp: 0.851 ± 0.03	1.41ValTyr: 1.41 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.017TrpAla: 1.017 ± 0.034	0.18TrpCys: 0.18 ± 0.012	0.723TrpAsp: 0.723 ± 0.026	0.715TrpGlu: 0.715 ± 0.023	0.466TrpPhe: 0.466 ± 0.021	0.941TrpGly: 0.941 ± 0.03	0.407TrpHis: 0.407 ± 0.019	0.698TrpIle: 0.698 ± 0.029	0.471TrpLys: 0.471 ± 0.019	1.851TrpLeu: 1.851 ± 0.053	0.422TrpMet: 0.422 ± 0.02	0.465TrpAsn: 0.465 ± 0.02	0.637TrpPro: 0.637 ± 0.025	1.022TrpGln: 1.022 ± 0.035	0.898TrpArg: 0.898 ± 0.03	0.889TrpSer: 0.889 ± 0.028	0.45TrpThr: 0.45 ± 0.027	0.985TrpVal: 0.985 ± 0.029	0.225TrpTrp: 0.225 ± 0.014	0.337TrpTyr: 0.337 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.377TyrAla: 2.377 ± 0.051	0.265TyrCys: 0.265 ± 0.016	1.388TyrAsp: 1.388 ± 0.036	1.261TyrGlu: 1.261 ± 0.033	0.944TyrPhe: 0.944 ± 0.033	2.233TyrGly: 2.233 ± 0.063	0.751TyrHis: 0.751 ± 0.027	0.929TyrIle: 0.929 ± 0.032	0.869TyrLys: 0.869 ± 0.029	2.8TyrLeu: 2.8 ± 0.052	0.617TyrMet: 0.617 ± 0.021	0.75TyrAsn: 0.75 ± 0.024	1.139TyrPro: 1.139 ± 0.035	1.326TyrGln: 1.326 ± 0.036	1.872TyrArg: 1.872 ± 0.046	1.379TyrSer: 1.379 ± 0.044	1.297TyrThr: 1.297 ± 0.044	1.537TyrVal: 1.537 ± 0.087	0.345TyrTrp: 0.345 ± 0.016	0.72TyrTyr: 0.72 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3594 proteins (1325866 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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