Amino acid dipepetide frequency for Tortoise microvirus 89

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.146AlaAla: 12.146 ± 4.319
0.0AlaCys: 0.0 ± 0.0
5.668AlaAsp: 5.668 ± 1.728
6.478AlaGlu: 6.478 ± 3.35
1.619AlaPhe: 1.619 ± 1.041
9.717AlaGly: 9.717 ± 4.336
1.619AlaHis: 1.619 ± 0.872
4.049AlaIle: 4.049 ± 1.921
3.239AlaLys: 3.239 ± 1.282
7.287AlaLeu: 7.287 ± 3.865
2.429AlaMet: 2.429 ± 1.807
1.619AlaAsn: 1.619 ± 1.059
4.049AlaPro: 4.049 ± 1.107
4.049AlaGln: 4.049 ± 2.111
5.668AlaArg: 5.668 ± 2.484
2.429AlaSer: 2.429 ± 1.618
5.668AlaThr: 5.668 ± 1.783
7.287AlaVal: 7.287 ± 2.664
1.619AlaTrp: 1.619 ± 0.872
2.429AlaTyr: 2.429 ± 0.888
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.81CysGlu: 0.81 ± 0.554
0.0CysPhe: 0.0 ± 0.0
0.81CysGly: 0.81 ± 0.906
0.81CysHis: 0.81 ± 0.554
1.619CysIle: 1.619 ± 1.109
0.81CysLys: 0.81 ± 0.906
0.81CysLeu: 0.81 ± 0.906
0.81CysMet: 0.81 ± 0.811
0.81CysAsn: 0.81 ± 0.554
0.81CysPro: 0.81 ± 0.906
0.81CysGln: 0.81 ± 1.083
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.668AspAla: 5.668 ± 1.735
0.0AspCys: 0.0 ± 0.0
4.049AspAsp: 4.049 ± 1.686
3.239AspGlu: 3.239 ± 1.897
4.049AspPhe: 4.049 ± 1.107
4.858AspGly: 4.858 ± 1.851
0.0AspHis: 0.0 ± 0.0
5.668AspIle: 5.668 ± 2.736
3.239AspLys: 3.239 ± 1.996
5.668AspLeu: 5.668 ± 2.853
0.81AspMet: 0.81 ± 0.959
1.619AspAsn: 1.619 ± 0.872
0.81AspPro: 0.81 ± 0.554
0.81AspGln: 0.81 ± 0.554
3.239AspArg: 3.239 ± 1.261
5.668AspSer: 5.668 ± 1.735
3.239AspThr: 3.239 ± 1.632
4.049AspVal: 4.049 ± 1.959
1.619AspTrp: 1.619 ± 1.273
3.239AspTyr: 3.239 ± 1.344
0.0AspXaa: 0.0 ± 0.0
Glu
4.049GluAla: 4.049 ± 2.903
1.619GluCys: 1.619 ± 0.872
1.619GluAsp: 1.619 ± 1.109
5.668GluGlu: 5.668 ± 2.054
3.239GluPhe: 3.239 ± 2.019
2.429GluGly: 2.429 ± 1.269
0.81GluHis: 0.81 ± 0.554
2.429GluIle: 2.429 ± 1.878
3.239GluLys: 3.239 ± 1.232
8.907GluLeu: 8.907 ± 1.737
0.81GluMet: 0.81 ± 0.959
3.239GluAsn: 3.239 ± 1.282
3.239GluPro: 3.239 ± 1.344
3.239GluGln: 3.239 ± 1.243
8.097GluArg: 8.097 ± 7.113
2.429GluSer: 2.429 ± 1.69
1.619GluThr: 1.619 ± 0.621
4.049GluVal: 4.049 ± 2.117
1.619GluTrp: 1.619 ± 1.059
5.668GluTyr: 5.668 ± 0.945
0.0GluXaa: 0.0 ± 0.0
Phe
5.668PheAla: 5.668 ± 3.139
0.81PheCys: 0.81 ± 0.554
3.239PheAsp: 3.239 ± 1.897
0.81PheGlu: 0.81 ± 0.554
3.239PhePhe: 3.239 ± 1.007
2.429PheGly: 2.429 ± 1.146
2.429PheHis: 2.429 ± 0.778
0.81PheIle: 0.81 ± 0.554
4.049PheLys: 4.049 ± 0.808
1.619PheLeu: 1.619 ± 1.07
1.619PheMet: 1.619 ± 0.872
0.81PheAsn: 0.81 ± 0.554
0.81PhePro: 0.81 ± 0.906
0.0PheGln: 0.0 ± 0.0
1.619PheArg: 1.619 ± 1.059
1.619PheSer: 1.619 ± 0.872
0.81PheThr: 0.81 ± 0.554
3.239PheVal: 3.239 ± 0.759
1.619PheTrp: 1.619 ± 1.109
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
8.097GlyAla: 8.097 ± 2.034
0.81GlyCys: 0.81 ± 0.906
5.668GlyAsp: 5.668 ± 2.174
5.668GlyGlu: 5.668 ± 1.369
0.81GlyPhe: 0.81 ± 0.906
3.239GlyGly: 3.239 ± 1.344
0.81GlyHis: 0.81 ± 0.554
3.239GlyIle: 3.239 ± 0.759
3.239GlyLys: 3.239 ± 1.53
7.287GlyLeu: 7.287 ± 2.207
1.619GlyMet: 1.619 ± 1.07
3.239GlyAsn: 3.239 ± 1.658
0.0GlyPro: 0.0 ± 0.0
4.049GlyGln: 4.049 ± 1.869
3.239GlyArg: 3.239 ± 1.658
1.619GlySer: 1.619 ± 1.109
4.858GlyThr: 4.858 ± 1.079
3.239GlyVal: 3.239 ± 1.575
0.81GlyTrp: 0.81 ± 0.906
3.239GlyTyr: 3.239 ± 1.575
0.0GlyXaa: 0.0 ± 0.0
His
1.619HisAla: 1.619 ± 1.059
0.0HisCys: 0.0 ± 0.0
1.619HisAsp: 1.619 ± 1.109
1.619HisGlu: 1.619 ± 1.917
1.619HisPhe: 1.619 ± 0.872
1.619HisGly: 1.619 ± 1.109
0.0HisHis: 0.0 ± 0.0
0.81HisIle: 0.81 ± 0.554
3.239HisLys: 3.239 ± 1.827
0.81HisLeu: 0.81 ± 0.906
0.81HisMet: 0.81 ± 0.554
0.0HisAsn: 0.0 ± 0.0
0.81HisPro: 0.81 ± 0.554
0.0HisGln: 0.0 ± 0.0
0.81HisArg: 0.81 ± 0.554
0.81HisSer: 0.81 ± 1.083
0.81HisThr: 0.81 ± 0.773
0.81HisVal: 0.81 ± 0.554
0.0HisTrp: 0.0 ± 0.0
3.239HisTyr: 3.239 ± 1.744
0.0HisXaa: 0.0 ± 0.0
Ile
4.049IleAla: 4.049 ± 2.227
0.0IleCys: 0.0 ± 0.0
1.619IleAsp: 1.619 ± 0.621
2.429IleGlu: 2.429 ± 1.618
3.239IlePhe: 3.239 ± 1.575
5.668IleGly: 5.668 ± 3.109
2.429IleHis: 2.429 ± 1.007
2.429IleIle: 2.429 ± 1.146
4.049IleLys: 4.049 ± 1.107
2.429IleLeu: 2.429 ± 0.778
1.619IleMet: 1.619 ± 1.115
0.81IleAsn: 0.81 ± 0.554
5.668IlePro: 5.668 ± 3.109
2.429IleGln: 2.429 ± 1.807
4.858IleArg: 4.858 ± 2.598
4.049IleSer: 4.049 ± 1.173
2.429IleThr: 2.429 ± 2.319
0.81IleVal: 0.81 ± 0.554
0.0IleTrp: 0.0 ± 0.0
2.429IleTyr: 2.429 ± 1.007
0.0IleXaa: 0.0 ± 0.0
Lys
3.239LysAla: 3.239 ± 1.232
0.81LysCys: 0.81 ± 0.906
4.049LysAsp: 4.049 ± 2.248
5.668LysGlu: 5.668 ± 2.409
1.619LysPhe: 1.619 ± 1.109
5.668LysGly: 5.668 ± 1.393
0.0LysHis: 0.0 ± 0.0
6.478LysIle: 6.478 ± 4.206
6.478LysLys: 6.478 ± 3.436
4.049LysLeu: 4.049 ± 1.151
3.239LysMet: 3.239 ± 1.919
2.429LysAsn: 2.429 ± 0.736
2.429LysPro: 2.429 ± 1.168
0.81LysGln: 0.81 ± 0.773
4.049LysArg: 4.049 ± 2.687
3.239LysSer: 3.239 ± 2.47
2.429LysThr: 2.429 ± 0.888
4.858LysVal: 4.858 ± 2.054
0.81LysTrp: 0.81 ± 1.083
2.429LysTyr: 2.429 ± 2.037
0.0LysXaa: 0.0 ± 0.0
Leu
4.858LeuAla: 4.858 ± 2.59
0.81LeuCys: 0.81 ± 0.906
4.858LeuAsp: 4.858 ± 1.753
4.049LeuGlu: 4.049 ± 2.227
0.81LeuPhe: 0.81 ± 0.773
2.429LeuGly: 2.429 ± 1.69
1.619LeuHis: 1.619 ± 1.059
4.049LeuIle: 4.049 ± 1.171
4.858LeuLys: 4.858 ± 1.453
1.619LeuLeu: 1.619 ± 1.109
2.429LeuMet: 2.429 ± 1.814
5.668LeuAsn: 5.668 ± 2.144
4.049LeuPro: 4.049 ± 2.128
4.858LeuGln: 4.858 ± 1.315
5.668LeuArg: 5.668 ± 2.217
7.287LeuSer: 7.287 ± 4.154
4.049LeuThr: 4.049 ± 2.843
4.049LeuVal: 4.049 ± 1.921
0.81LeuTrp: 0.81 ± 0.554
4.049LeuTyr: 4.049 ± 1.151
0.0LeuXaa: 0.0 ± 0.0
Met
4.858MetAla: 4.858 ± 2.577
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
4.049MetGlu: 4.049 ± 1.686
0.0MetPhe: 0.0 ± 0.0
1.619MetGly: 1.619 ± 1.109
0.81MetHis: 0.81 ± 0.554
1.619MetIle: 1.619 ± 1.109
0.81MetLys: 0.81 ± 0.959
0.81MetLeu: 0.81 ± 1.083
0.81MetMet: 0.81 ± 0.773
1.619MetAsn: 1.619 ± 0.621
4.049MetPro: 4.049 ± 1.76
1.619MetGln: 1.619 ± 1.546
2.429MetArg: 2.429 ± 1.288
2.429MetSer: 2.429 ± 1.69
1.619MetThr: 1.619 ± 1.813
0.81MetVal: 0.81 ± 0.554
0.0MetTrp: 0.0 ± 0.0
2.429MetTyr: 2.429 ± 1.007
0.0MetXaa: 0.0 ± 0.0
Asn
2.429AsnAla: 2.429 ± 0.778
0.0AsnCys: 0.0 ± 0.0
4.858AsnAsp: 4.858 ± 1.453
4.049AsnGlu: 4.049 ± 1.869
1.619AsnPhe: 1.619 ± 1.109
0.81AsnGly: 0.81 ± 0.906
0.81AsnHis: 0.81 ± 0.959
0.0AsnIle: 0.0 ± 0.0
4.858AsnLys: 4.858 ± 1.389
4.858AsnLeu: 4.858 ± 2.577
3.239AsnMet: 3.239 ± 1.243
0.81AsnAsn: 0.81 ± 0.959
4.049AsnPro: 4.049 ± 1.032
1.619AsnGln: 1.619 ± 1.109
2.429AsnArg: 2.429 ± 1.269
3.239AsnSer: 3.239 ± 0.826
2.429AsnThr: 2.429 ± 1.146
2.429AsnVal: 2.429 ± 0.888
1.619AsnTrp: 1.619 ± 0.948
3.239AsnTyr: 3.239 ± 1.575
0.0AsnXaa: 0.0 ± 0.0
Pro
2.429ProAla: 2.429 ± 0.888
0.81ProCys: 0.81 ± 0.906
4.049ProAsp: 4.049 ± 1.553
2.429ProGlu: 2.429 ± 1.146
2.429ProPhe: 2.429 ± 0.888
1.619ProGly: 1.619 ± 1.109
0.81ProHis: 0.81 ± 0.906
3.239ProIle: 3.239 ± 2.217
0.81ProLys: 0.81 ± 0.554
4.049ProLeu: 4.049 ± 1.559
1.619ProMet: 1.619 ± 1.109
3.239ProAsn: 3.239 ± 1.243
0.0ProPro: 0.0 ± 0.0
0.81ProGln: 0.81 ± 0.554
3.239ProArg: 3.239 ± 1.658
4.049ProSer: 4.049 ± 1.925
3.239ProThr: 3.239 ± 1.344
4.858ProVal: 4.858 ± 0.895
0.0ProTrp: 0.0 ± 0.0
0.81ProTyr: 0.81 ± 0.554
0.0ProXaa: 0.0 ± 0.0
Gln
3.239GlnAla: 3.239 ± 1.243
0.81GlnCys: 0.81 ± 0.554
2.429GlnAsp: 2.429 ± 0.736
3.239GlnGlu: 3.239 ± 1.344
0.81GlnPhe: 0.81 ± 0.554
2.429GlnGly: 2.429 ± 0.888
0.81GlnHis: 0.81 ± 0.554
2.429GlnIle: 2.429 ± 2.319
3.239GlnLys: 3.239 ± 2.371
1.619GlnLeu: 1.619 ± 0.621
0.81GlnMet: 0.81 ± 0.773
2.429GlnAsn: 2.429 ± 1.007
1.619GlnPro: 1.619 ± 1.109
4.049GlnGln: 4.049 ± 1.429
4.858GlnArg: 4.858 ± 2.577
0.0GlnSer: 0.0 ± 0.0
0.81GlnThr: 0.81 ± 0.554
3.239GlnVal: 3.239 ± 1.01
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
8.097ArgAla: 8.097 ± 2.498
0.0ArgCys: 0.0 ± 0.0
4.858ArgAsp: 4.858 ± 3.183
4.049ArgGlu: 4.049 ± 2.504
4.049ArgPhe: 4.049 ± 1.171
1.619ArgGly: 1.619 ± 1.07
0.81ArgHis: 0.81 ± 0.554
4.858ArgIle: 4.858 ± 0.952
3.239ArgLys: 3.239 ± 2.784
4.858ArgLeu: 4.858 ± 1.786
2.429ArgMet: 2.429 ± 1.007
3.239ArgAsn: 3.239 ± 0.879
3.239ArgPro: 3.239 ± 0.759
1.619ArgGln: 1.619 ± 1.109
5.668ArgArg: 5.668 ± 2.121
3.239ArgSer: 3.239 ± 1.228
3.239ArgThr: 3.239 ± 1.964
4.049ArgVal: 4.049 ± 2.028
0.81ArgTrp: 0.81 ± 0.554
6.478ArgTyr: 6.478 ± 2.325
0.0ArgXaa: 0.0 ± 0.0
Ser
5.668SerAla: 5.668 ± 2.353
0.0SerCys: 0.0 ± 0.0
3.239SerAsp: 3.239 ± 1.01
5.668SerGlu: 5.668 ± 1.824
1.619SerPhe: 1.619 ± 1.356
2.429SerGly: 2.429 ± 1.146
1.619SerHis: 1.619 ± 0.872
3.239SerIle: 3.239 ± 1.228
4.858SerLys: 4.858 ± 3.628
3.239SerLeu: 3.239 ± 1.964
0.81SerMet: 0.81 ± 0.92
1.619SerAsn: 1.619 ± 0.948
1.619SerPro: 1.619 ± 0.621
0.81SerGln: 0.81 ± 0.554
3.239SerArg: 3.239 ± 0.826
2.429SerSer: 2.429 ± 0.888
5.668SerThr: 5.668 ± 2.327
1.619SerVal: 1.619 ± 0.872
0.81SerTrp: 0.81 ± 0.773
0.81SerTyr: 0.81 ± 0.773
0.0SerXaa: 0.0 ± 0.0
Thr
5.668ThrAla: 5.668 ± 1.359
0.81ThrCys: 0.81 ± 0.554
2.429ThrAsp: 2.429 ± 1.288
1.619ThrGlu: 1.619 ± 1.041
1.619ThrPhe: 1.619 ± 0.872
8.097ThrGly: 8.097 ± 1.242
0.81ThrHis: 0.81 ± 0.773
4.049ThrIle: 4.049 ± 1.959
3.239ThrLys: 3.239 ± 1.261
6.478ThrLeu: 6.478 ± 3.638
0.81ThrMet: 0.81 ± 0.554
5.668ThrAsn: 5.668 ± 1.515
4.049ThrPro: 4.049 ± 1.171
0.0ThrGln: 0.0 ± 0.0
1.619ThrArg: 1.619 ± 1.059
1.619ThrSer: 1.619 ± 1.059
4.858ThrThr: 4.858 ± 1.776
0.0ThrVal: 0.0 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
0.81ThrTyr: 0.81 ± 0.906
0.0ThrXaa: 0.0 ± 0.0
Val
3.239ValAla: 3.239 ± 1.344
0.0ValCys: 0.0 ± 0.0
3.239ValAsp: 3.239 ± 1.344
3.239ValGlu: 3.239 ± 2.082
1.619ValPhe: 1.619 ± 0.948
4.049ValGly: 4.049 ± 1.824
1.619ValHis: 1.619 ± 0.872
0.81ValIle: 0.81 ± 0.554
4.858ValLys: 4.858 ± 2.213
4.049ValLeu: 4.049 ± 1.429
2.429ValMet: 2.429 ± 1.663
2.429ValAsn: 2.429 ± 1.168
2.429ValPro: 2.429 ± 1.222
4.049ValGln: 4.049 ± 1.559
6.478ValArg: 6.478 ± 1.313
1.619ValSer: 1.619 ± 1.109
3.239ValThr: 3.239 ± 2.568
1.619ValVal: 1.619 ± 1.813
1.619ValTrp: 1.619 ± 1.109
2.429ValTyr: 2.429 ± 0.888
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.619TrpAsp: 1.619 ± 1.109
1.619TrpGlu: 1.619 ± 1.041
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.619TrpHis: 1.619 ± 1.041
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.81TrpLeu: 0.81 ± 0.959
0.81TrpMet: 0.81 ± 0.554
2.429TrpAsn: 2.429 ± 1.618
0.81TrpPro: 0.81 ± 0.554
0.81TrpGln: 0.81 ± 0.554
1.619TrpArg: 1.619 ± 0.621
1.619TrpSer: 1.619 ± 1.813
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.049TyrAla: 4.049 ± 0.808
1.619TyrCys: 1.619 ± 1.041
2.429TyrAsp: 2.429 ± 1.606
1.619TyrGlu: 1.619 ± 1.273
3.239TyrPhe: 3.239 ± 2.217
3.239TyrGly: 3.239 ± 2.665
0.81TyrHis: 0.81 ± 0.906
2.429TyrIle: 2.429 ± 1.663
2.429TyrLys: 2.429 ± 1.269
1.619TyrLeu: 1.619 ± 0.872
1.619TyrMet: 1.619 ± 0.872
5.668TyrAsn: 5.668 ± 2.017
0.0TyrPro: 0.0 ± 0.0
2.429TyrGln: 2.429 ± 0.888
1.619TyrArg: 1.619 ± 1.109
1.619TyrSer: 1.619 ± 0.948
3.239TyrThr: 3.239 ± 1.241
4.049TyrVal: 4.049 ± 1.559
0.0TyrTrp: 0.0 ± 0.0
4.858TyrTyr: 4.858 ± 2.516
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1236 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski