Amino acid dipepetide frequency for Ubei picorna-like virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.446AlaAla: 4.446 ± 0.094
0.404AlaCys: 0.404 ± 0.224
7.276AlaAsp: 7.276 ± 0.833
4.446AlaGlu: 4.446 ± 1.184
3.638AlaPhe: 3.638 ± 0.097
4.85AlaGly: 4.85 ± 1.787
1.213AlaHis: 1.213 ± 0.671
4.446AlaIle: 4.446 ± 0.545
3.234AlaLys: 3.234 ± 0.512
7.276AlaLeu: 7.276 ± 0.194
2.425AlaMet: 2.425 ± 0.574
4.446AlaAsn: 4.446 ± 0.094
4.446AlaPro: 4.446 ± 2.011
2.829AlaGln: 2.829 ± 0.927
2.829AlaArg: 2.829 ± 0.289
6.871AlaSer: 6.871 ± 3.224
6.871AlaThr: 6.871 ± 0.668
6.467AlaVal: 6.467 ± 1.531
0.808AlaTrp: 0.808 ± 0.191
3.638AlaTyr: 3.638 ± 0.097
0.0AlaXaa: 0.0 ± 0.0
Cys
0.808CysAla: 0.808 ± 0.191
0.0CysCys: 0.0 ± 0.0
0.404CysAsp: 0.404 ± 0.224
0.404CysGlu: 0.404 ± 0.224
0.0CysPhe: 0.0 ± 0.0
1.213CysGly: 1.213 ± 0.671
0.0CysHis: 0.0 ± 0.0
0.404CysIle: 0.404 ± 0.224
1.617CysLys: 1.617 ± 0.383
1.213CysLeu: 1.213 ± 0.671
0.808CysMet: 0.808 ± 0.191
1.213CysAsn: 1.213 ± 0.671
1.617CysPro: 1.617 ± 0.895
0.0CysGln: 0.0 ± 0.0
1.213CysArg: 1.213 ± 0.032
0.808CysSer: 0.808 ± 0.448
1.617CysThr: 1.617 ± 0.895
2.425CysVal: 2.425 ± 1.343
0.808CysTrp: 0.808 ± 0.191
0.404CysTyr: 0.404 ± 0.224
0.0CysXaa: 0.0 ± 0.0
Asp
2.829AspAla: 2.829 ± 0.989
0.808AspCys: 0.808 ± 0.191
3.638AspAsp: 3.638 ± 1.375
3.234AspGlu: 3.234 ± 0.512
2.829AspPhe: 2.829 ± 0.35
2.425AspGly: 2.425 ± 0.065
0.404AspHis: 0.404 ± 0.224
2.425AspIle: 2.425 ± 0.065
2.829AspLys: 2.829 ± 0.927
5.659AspLeu: 5.659 ± 1.855
3.234AspMet: 3.234 ± 0.512
2.021AspAsn: 2.021 ± 0.159
3.234AspPro: 3.234 ± 1.404
1.617AspGln: 1.617 ± 0.383
2.425AspArg: 2.425 ± 1.343
2.021AspSer: 2.021 ± 0.48
6.063AspThr: 6.063 ± 0.162
7.276AspVal: 7.276 ± 0.833
0.404AspTrp: 0.404 ± 0.224
1.213AspTyr: 1.213 ± 0.032
0.0AspXaa: 0.0 ± 0.0
Glu
5.659GluAla: 5.659 ± 1.855
0.808GluCys: 0.808 ± 0.191
1.617GluAsp: 1.617 ± 0.256
2.021GluGlu: 2.021 ± 0.48
2.021GluPhe: 2.021 ± 0.159
0.404GluGly: 0.404 ± 0.224
0.404GluHis: 0.404 ± 0.415
1.213GluIle: 1.213 ± 0.032
3.638GluLys: 3.638 ± 1.375
4.042GluLeu: 4.042 ± 0.318
1.213GluMet: 1.213 ± 0.032
0.404GluAsn: 0.404 ± 0.415
2.829GluPro: 2.829 ± 0.35
1.617GluGln: 1.617 ± 0.383
2.425GluArg: 2.425 ± 1.343
3.234GluSer: 3.234 ± 0.512
3.638GluThr: 3.638 ± 0.097
4.042GluVal: 4.042 ± 0.96
1.213GluTrp: 1.213 ± 0.671
3.234GluTyr: 3.234 ± 1.151
0.0GluXaa: 0.0 ± 0.0
Phe
2.425PheAla: 2.425 ± 1.213
0.808PheCys: 0.808 ± 0.448
3.234PheAsp: 3.234 ± 0.512
2.021PheGlu: 2.021 ± 0.48
1.617PhePhe: 1.617 ± 0.256
2.021PheGly: 2.021 ± 0.159
1.213PheHis: 1.213 ± 0.032
2.829PheIle: 2.829 ± 0.289
1.213PheLys: 1.213 ± 0.032
5.255PheLeu: 5.255 ± 0.992
0.404PheMet: 0.404 ± 0.224
4.042PheAsn: 4.042 ± 1.596
1.617PhePro: 1.617 ± 0.256
1.617PheGln: 1.617 ± 0.383
1.213PheArg: 1.213 ± 0.671
4.042PheSer: 4.042 ± 1.596
4.042PheThr: 4.042 ± 0.321
2.021PheVal: 2.021 ± 1.437
2.829PheTrp: 2.829 ± 0.927
1.617PheTyr: 1.617 ± 1.022
0.0PheXaa: 0.0 ± 0.0
Gly
5.659GlyAla: 5.659 ± 1.339
1.213GlyCys: 1.213 ± 0.032
3.234GlyAsp: 3.234 ± 1.151
2.021GlyGlu: 2.021 ± 0.798
1.213GlyPhe: 1.213 ± 0.671
3.638GlyGly: 3.638 ± 0.736
1.213GlyHis: 1.213 ± 0.671
4.446GlyIle: 4.446 ± 1.184
3.638GlyLys: 3.638 ± 0.736
3.234GlyLeu: 3.234 ± 1.404
1.213GlyMet: 1.213 ± 0.032
0.808GlyAsn: 0.808 ± 0.448
2.021GlyPro: 2.021 ± 0.798
1.213GlyGln: 1.213 ± 0.032
4.042GlyArg: 4.042 ± 0.957
6.467GlySer: 6.467 ± 0.892
6.063GlyThr: 6.063 ± 1.755
4.446GlyVal: 4.446 ± 0.094
1.213GlyTrp: 1.213 ± 0.032
3.234GlyTyr: 3.234 ± 0.765
0.0GlyXaa: 0.0 ± 0.0
His
1.213HisAla: 1.213 ± 0.032
0.808HisCys: 0.808 ± 0.191
0.404HisAsp: 0.404 ± 0.224
1.213HisGlu: 1.213 ± 0.032
1.617HisPhe: 1.617 ± 0.256
2.021HisGly: 2.021 ± 0.48
0.404HisHis: 0.404 ± 0.224
0.808HisIle: 0.808 ± 0.448
0.404HisLys: 0.404 ± 0.415
1.213HisLeu: 1.213 ± 0.032
1.213HisMet: 1.213 ± 0.032
0.808HisAsn: 0.808 ± 0.448
0.808HisPro: 0.808 ± 0.191
0.808HisGln: 0.808 ± 0.448
0.404HisArg: 0.404 ± 0.224
1.213HisSer: 1.213 ± 0.671
1.617HisThr: 1.617 ± 0.895
1.617HisVal: 1.617 ± 0.895
0.0HisTrp: 0.0 ± 0.0
0.404HisTyr: 0.404 ± 0.224
0.0HisXaa: 0.0 ± 0.0
Ile
4.85IleAla: 4.85 ± 0.13
0.808IleCys: 0.808 ± 0.448
2.829IleAsp: 2.829 ± 0.989
3.638IleGlu: 3.638 ± 0.097
1.213IlePhe: 1.213 ± 0.671
3.638IleGly: 3.638 ± 0.097
1.617IleHis: 1.617 ± 0.895
2.829IleIle: 2.829 ± 0.289
3.638IleLys: 3.638 ± 2.014
1.213IleLeu: 1.213 ± 0.671
1.617IleMet: 1.617 ± 0.383
2.021IleAsn: 2.021 ± 0.798
2.829IlePro: 2.829 ± 0.35
1.617IleGln: 1.617 ± 0.383
1.617IleArg: 1.617 ± 0.256
4.042IleSer: 4.042 ± 0.957
2.021IleThr: 2.021 ± 0.48
3.234IleVal: 3.234 ± 0.765
0.808IleTrp: 0.808 ± 0.191
1.213IleTyr: 1.213 ± 0.032
0.0IleXaa: 0.0 ± 0.0
Lys
0.808LysAla: 0.808 ± 0.448
0.404LysCys: 0.404 ± 0.224
2.829LysAsp: 2.829 ± 1.566
1.213LysGlu: 1.213 ± 0.032
3.638LysPhe: 3.638 ± 0.097
2.425LysGly: 2.425 ± 0.065
2.021LysHis: 2.021 ± 0.48
2.829LysIle: 2.829 ± 0.35
2.021LysLys: 2.021 ± 1.119
6.467LysLeu: 6.467 ± 0.386
1.213LysMet: 1.213 ± 0.671
2.021LysAsn: 2.021 ± 0.159
1.617LysPro: 1.617 ± 0.895
0.0LysGln: 0.0 ± 0.0
4.446LysArg: 4.446 ± 2.461
4.042LysSer: 4.042 ± 0.96
1.213LysThr: 1.213 ± 0.671
3.234LysVal: 3.234 ± 0.127
0.808LysTrp: 0.808 ± 0.448
3.234LysTyr: 3.234 ± 0.127
0.0LysXaa: 0.0 ± 0.0
Leu
7.276LeuAla: 7.276 ± 1.472
2.829LeuCys: 2.829 ± 0.927
7.276LeuAsp: 7.276 ± 0.194
5.255LeuGlu: 5.255 ± 0.353
2.425LeuPhe: 2.425 ± 0.574
5.659LeuGly: 5.659 ± 1.216
0.0LeuHis: 0.0 ± 0.0
2.829LeuIle: 2.829 ± 0.289
4.042LeuLys: 4.042 ± 0.96
5.255LeuLeu: 5.255 ± 0.992
2.021LeuMet: 2.021 ± 1.119
4.446LeuAsn: 4.446 ± 0.733
2.829LeuPro: 2.829 ± 1.628
0.808LeuGln: 0.808 ± 0.448
3.638LeuArg: 3.638 ± 0.097
6.063LeuSer: 6.063 ± 0.162
5.659LeuThr: 5.659 ± 3.895
4.042LeuVal: 4.042 ± 1.599
0.404LeuTrp: 0.404 ± 0.415
2.829LeuTyr: 2.829 ± 0.289
0.0LeuXaa: 0.0 ± 0.0
Met
1.617MetAla: 1.617 ± 0.256
0.404MetCys: 0.404 ± 0.224
1.617MetAsp: 1.617 ± 0.895
0.808MetGlu: 0.808 ± 0.448
2.829MetPhe: 2.829 ± 0.289
1.617MetGly: 1.617 ± 0.383
0.404MetHis: 0.404 ± 0.224
0.808MetIle: 0.808 ± 0.191
1.213MetLys: 1.213 ± 0.671
1.617MetLeu: 1.617 ± 0.256
0.0MetMet: 0.0 ± 0.0
1.213MetAsn: 1.213 ± 0.032
0.808MetPro: 0.808 ± 0.448
1.617MetGln: 1.617 ± 0.256
2.021MetArg: 2.021 ± 0.48
1.617MetSer: 1.617 ± 0.383
2.021MetThr: 2.021 ± 0.159
3.234MetVal: 3.234 ± 0.127
0.0MetTrp: 0.0 ± 0.0
2.425MetTyr: 2.425 ± 0.574
0.0MetXaa: 0.0 ± 0.0
Asn
3.638AsnAla: 3.638 ± 1.18
0.404AsnCys: 0.404 ± 0.224
2.425AsnAsp: 2.425 ± 0.574
2.021AsnGlu: 2.021 ± 0.159
3.234AsnPhe: 3.234 ± 1.404
2.021AsnGly: 2.021 ± 0.48
0.808AsnHis: 0.808 ± 0.448
2.829AsnIle: 2.829 ± 0.989
0.808AsnLys: 0.808 ± 0.191
2.021AsnLeu: 2.021 ± 0.798
0.808AsnMet: 0.808 ± 0.269
3.638AsnAsn: 3.638 ± 0.097
3.234AsnPro: 3.234 ± 0.127
1.617AsnGln: 1.617 ± 0.383
2.021AsnArg: 2.021 ± 0.48
1.617AsnSer: 1.617 ± 0.256
3.638AsnThr: 3.638 ± 0.736
5.255AsnVal: 5.255 ± 0.285
0.808AsnTrp: 0.808 ± 0.83
2.829AsnTyr: 2.829 ± 0.989
0.0AsnXaa: 0.0 ± 0.0
Pro
3.638ProAla: 3.638 ± 0.542
0.404ProCys: 0.404 ± 0.224
3.638ProAsp: 3.638 ± 0.542
2.425ProGlu: 2.425 ± 0.704
3.234ProPhe: 3.234 ± 1.151
4.446ProGly: 4.446 ± 2.011
0.404ProHis: 0.404 ± 0.415
1.213ProIle: 1.213 ± 0.032
1.213ProLys: 1.213 ± 0.606
4.446ProLeu: 4.446 ± 0.733
0.808ProMet: 0.808 ± 0.448
2.021ProAsn: 2.021 ± 0.159
2.829ProPro: 2.829 ± 0.927
1.617ProGln: 1.617 ± 1.022
0.808ProArg: 0.808 ± 0.191
2.829ProSer: 2.829 ± 0.35
7.276ProThr: 7.276 ± 1.083
7.276ProVal: 7.276 ± 2.361
0.808ProTrp: 0.808 ± 0.191
2.021ProTyr: 2.021 ± 0.798
0.0ProXaa: 0.0 ± 0.0
Gln
5.255GlnAla: 5.255 ± 1.631
0.808GlnCys: 0.808 ± 0.191
1.213GlnAsp: 1.213 ± 0.671
0.808GlnGlu: 0.808 ± 0.448
2.021GlnPhe: 2.021 ± 1.437
2.021GlnGly: 2.021 ± 0.798
1.617GlnHis: 1.617 ± 0.895
0.404GlnIle: 0.404 ± 0.415
1.213GlnLys: 1.213 ± 0.032
1.617GlnLeu: 1.617 ± 0.383
0.404GlnMet: 0.404 ± 0.186
1.617GlnAsn: 1.617 ± 1.022
1.213GlnPro: 1.213 ± 0.032
0.808GlnGln: 0.808 ± 0.191
2.425GlnArg: 2.425 ± 0.704
4.85GlnSer: 4.85 ± 1.787
1.617GlnThr: 1.617 ± 0.383
0.404GlnVal: 0.404 ± 0.224
0.404GlnTrp: 0.404 ± 0.224
0.404GlnTyr: 0.404 ± 0.224
0.0GlnXaa: 0.0 ± 0.0
Arg
2.829ArgAla: 2.829 ± 0.35
0.404ArgCys: 0.404 ± 0.224
1.617ArgAsp: 1.617 ± 0.895
2.829ArgGlu: 2.829 ± 0.927
2.425ArgPhe: 2.425 ± 0.704
4.446ArgGly: 4.446 ± 0.545
0.808ArgHis: 0.808 ± 0.448
2.829ArgIle: 2.829 ± 0.35
2.829ArgLys: 2.829 ± 0.927
2.829ArgLeu: 2.829 ± 2.267
2.021ArgMet: 2.021 ± 0.159
2.425ArgAsn: 2.425 ± 0.065
4.042ArgPro: 4.042 ± 0.321
0.808ArgGln: 0.808 ± 0.448
2.021ArgArg: 2.021 ± 0.48
4.042ArgSer: 4.042 ± 0.96
3.234ArgThr: 3.234 ± 1.151
3.638ArgVal: 3.638 ± 0.542
0.808ArgTrp: 0.808 ± 0.448
1.617ArgTyr: 1.617 ± 0.895
0.0ArgXaa: 0.0 ± 0.0
Ser
8.084SerAla: 8.084 ± 1.913
0.808SerCys: 0.808 ± 0.448
4.042SerAsp: 4.042 ± 2.234
2.829SerGlu: 2.829 ± 0.35
3.234SerPhe: 3.234 ± 0.765
6.063SerGly: 6.063 ± 1.755
1.213SerHis: 1.213 ± 0.032
3.234SerIle: 3.234 ± 0.765
3.638SerLys: 3.638 ± 1.375
3.638SerLeu: 3.638 ± 0.736
4.042SerMet: 4.042 ± 0.321
4.446SerAsn: 4.446 ± 1.372
2.829SerPro: 2.829 ± 0.989
1.617SerGln: 1.617 ± 0.383
3.638SerArg: 3.638 ± 0.542
2.829SerSer: 2.829 ± 0.927
7.68SerThr: 7.68 ± 3.415
6.063SerVal: 6.063 ± 0.477
0.404SerTrp: 0.404 ± 0.224
2.829SerTyr: 2.829 ± 0.289
0.0SerXaa: 0.0 ± 0.0
Thr
7.276ThrAla: 7.276 ± 2.361
1.213ThrCys: 1.213 ± 0.671
2.425ThrAsp: 2.425 ± 0.574
2.425ThrGlu: 2.425 ± 0.704
2.425ThrPhe: 2.425 ± 1.213
2.425ThrGly: 2.425 ± 0.574
1.617ThrHis: 1.617 ± 0.256
2.829ThrIle: 2.829 ± 0.989
3.234ThrLys: 3.234 ± 1.151
7.276ThrLeu: 7.276 ± 0.194
1.617ThrMet: 1.617 ± 0.256
4.446ThrAsn: 4.446 ± 0.733
6.063ThrPro: 6.063 ± 2.393
4.042ThrGln: 4.042 ± 0.321
3.638ThrArg: 3.638 ± 0.097
7.276ThrSer: 7.276 ± 4.277
6.063ThrThr: 6.063 ± 0.477
8.084ThrVal: 8.084 ± 0.003
2.829ThrTrp: 2.829 ± 0.35
3.234ThrTyr: 3.234 ± 0.512
0.0ThrXaa: 0.0 ± 0.0
Val
10.105ValAla: 10.105 ± 0.483
0.808ValCys: 0.808 ± 0.448
4.446ValAsp: 4.446 ± 1.184
3.638ValGlu: 3.638 ± 0.736
1.617ValPhe: 1.617 ± 0.383
5.255ValGly: 5.255 ± 0.285
2.829ValHis: 2.829 ± 0.289
6.063ValIle: 6.063 ± 1.44
3.638ValLys: 3.638 ± 1.18
6.467ValLeu: 6.467 ± 1.025
0.404ValMet: 0.404 ± 0.224
2.829ValAsn: 2.829 ± 0.289
6.063ValPro: 6.063 ± 1.755
4.042ValGln: 4.042 ± 0.318
4.85ValArg: 4.85 ± 0.13
5.659ValSer: 5.659 ± 1.978
4.85ValThr: 4.85 ± 0.509
7.276ValVal: 7.276 ± 0.444
1.213ValTrp: 1.213 ± 0.606
2.425ValTyr: 2.425 ± 0.065
0.0ValXaa: 0.0 ± 0.0
Trp
2.021TrpAla: 2.021 ± 1.437
0.808TrpCys: 0.808 ± 0.448
0.404TrpAsp: 0.404 ± 0.224
1.213TrpGlu: 1.213 ± 0.032
1.213TrpPhe: 1.213 ± 0.671
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.808TrpIle: 0.808 ± 0.191
0.404TrpLys: 0.404 ± 0.224
0.808TrpLeu: 0.808 ± 0.191
0.0TrpMet: 0.0 ± 0.0
0.404TrpAsn: 0.404 ± 0.224
0.404TrpPro: 0.404 ± 0.224
0.0TrpGln: 0.0 ± 0.0
1.213TrpArg: 1.213 ± 0.606
1.213TrpSer: 1.213 ± 0.032
1.617TrpThr: 1.617 ± 0.383
1.617TrpVal: 1.617 ± 0.383
0.0TrpTrp: 0.0 ± 0.0
2.425TrpTyr: 2.425 ± 1.343
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.425TyrAla: 2.425 ± 0.704
2.021TyrCys: 2.021 ± 1.119
2.021TyrAsp: 2.021 ± 0.159
1.213TyrGlu: 1.213 ± 0.671
3.638TyrPhe: 3.638 ± 0.542
3.638TyrGly: 3.638 ± 0.097
0.808TyrHis: 0.808 ± 0.191
1.213TyrIle: 1.213 ± 0.671
2.021TyrLys: 2.021 ± 0.48
4.042TyrLeu: 4.042 ± 0.96
2.021TyrMet: 2.021 ± 0.159
0.808TyrAsn: 0.808 ± 0.191
2.021TyrPro: 2.021 ± 0.48
2.829TyrGln: 2.829 ± 0.35
1.617TyrArg: 1.617 ± 1.022
2.425TyrSer: 2.425 ± 0.574
3.638TyrThr: 3.638 ± 2.458
2.829TyrVal: 2.829 ± 1.566
0.0TyrTrp: 0.0 ± 0.0
0.808TyrTyr: 0.808 ± 0.83
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2475 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski