Amino acid dipepetide frequency for Wuhan tick virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.875AlaAla: 4.875 ± 0.496
0.914AlaCys: 0.914 ± 0.489
3.352AlaAsp: 3.352 ± 0.301
3.961AlaGlu: 3.961 ± 1.151
3.352AlaPhe: 3.352 ± 0.8
3.961AlaGly: 3.961 ± 1.09
0.609AlaHis: 0.609 ± 0.359
4.875AlaIle: 4.875 ± 0.827
3.961AlaLys: 3.961 ± 1.151
5.484AlaLeu: 5.484 ± 1.03
2.133AlaMet: 2.133 ± 0.548
4.266AlaAsn: 4.266 ± 1.639
2.742AlaPro: 2.742 ± 0.598
3.047AlaGln: 3.047 ± 0.502
3.656AlaArg: 3.656 ± 0.264
4.266AlaSer: 4.266 ± 0.607
3.961AlaThr: 3.961 ± 2.139
4.57AlaVal: 4.57 ± 1.599
1.219AlaTrp: 1.219 ± 0.343
3.352AlaTyr: 3.352 ± 0.323
0.0AlaXaa: 0.0 ± 0.0
Cys
0.914CysAla: 0.914 ± 0.653
0.609CysCys: 0.609 ± 0.267
1.219CysAsp: 1.219 ± 0.652
0.305CysGlu: 0.305 ± 0.394
0.914CysPhe: 0.914 ± 0.199
0.914CysGly: 0.914 ± 0.653
0.609CysHis: 0.609 ± 0.267
2.438CysIle: 2.438 ± 0.901
1.219CysLys: 1.219 ± 0.652
3.352CysLeu: 3.352 ± 0.301
1.219CysMet: 1.219 ± 0.652
0.914CysAsn: 0.914 ± 0.199
0.609CysPro: 0.609 ± 0.326
0.914CysGln: 0.914 ± 0.199
1.523CysArg: 1.523 ± 0.37
0.609CysSer: 0.609 ± 0.657
1.828CysThr: 1.828 ± 0.8
1.523CysVal: 1.523 ± 0.203
0.0CysTrp: 0.0 ± 0.0
2.133CysTyr: 2.133 ± 0.217
0.0CysXaa: 0.0 ± 0.0
Asp
3.047AspAla: 3.047 ± 1.337
1.828AspCys: 1.828 ± 0.8
2.742AspAsp: 2.742 ± 0.984
3.352AspGlu: 3.352 ± 1.793
1.219AspPhe: 1.219 ± 0.248
1.219AspGly: 1.219 ± 0.248
1.523AspHis: 1.523 ± 0.815
3.352AspIle: 3.352 ± 1.086
1.219AspLys: 1.219 ± 0.652
5.484AspLeu: 5.484 ± 0.613
0.914AspMet: 0.914 ± 0.498
2.742AspAsn: 2.742 ± 0.904
3.656AspPro: 3.656 ± 0.744
1.219AspGln: 1.219 ± 0.248
2.742AspArg: 2.742 ± 1.055
3.047AspSer: 3.047 ± 0.437
2.133AspThr: 2.133 ± 0.702
3.352AspVal: 3.352 ± 0.327
0.914AspTrp: 0.914 ± 0.199
3.047AspTyr: 3.047 ± 1.63
0.0AspXaa: 0.0 ± 0.0
Glu
3.961GluAla: 3.961 ± 1.748
1.523GluCys: 1.523 ± 0.37
3.352GluAsp: 3.352 ± 0.834
5.484GluGlu: 5.484 ± 1.078
2.742GluPhe: 2.742 ± 0.54
4.266GluGly: 4.266 ± 0.405
2.133GluHis: 2.133 ± 0.702
3.352GluIle: 3.352 ± 1.16
2.133GluLys: 2.133 ± 0.668
6.094GluLeu: 6.094 ± 0.908
1.523GluMet: 1.523 ± 0.773
0.914GluAsn: 0.914 ± 0.331
1.523GluPro: 1.523 ± 0.661
2.742GluGln: 2.742 ± 0.994
2.133GluArg: 2.133 ± 0.668
2.133GluSer: 2.133 ± 1.141
2.133GluThr: 2.133 ± 0.668
3.656GluVal: 3.656 ± 1.527
1.219GluTrp: 1.219 ± 0.248
2.438GluTyr: 2.438 ± 0.481
0.0GluXaa: 0.0 ± 0.0
Phe
2.438PheAla: 2.438 ± 0.825
0.914PheCys: 0.914 ± 0.331
2.742PheAsp: 2.742 ± 0.515
1.219PheGlu: 1.219 ± 0.248
1.828PhePhe: 1.828 ± 0.399
2.133PheGly: 2.133 ± 0.217
0.914PheHis: 0.914 ± 0.653
3.656PheIle: 3.656 ± 0.488
2.133PheLys: 2.133 ± 1.699
6.399PheLeu: 6.399 ± 2.042
1.219PheMet: 1.219 ± 0.533
2.438PheAsn: 2.438 ± 0.992
2.742PhePro: 2.742 ± 1.055
2.133PheGln: 2.133 ± 0.42
2.133PheArg: 2.133 ± 0.217
3.656PheSer: 3.656 ± 1.142
2.438PheThr: 2.438 ± 0.901
3.047PheVal: 3.047 ± 1.144
0.609PheTrp: 0.609 ± 0.267
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.352GlyAla: 3.352 ± 0.881
0.609GlyCys: 0.609 ± 0.267
3.352GlyAsp: 3.352 ± 0.301
3.047GlyGlu: 3.047 ± 0.976
3.656GlyPhe: 3.656 ± 0.744
3.656GlyGly: 3.656 ± 1.03
2.133GlyHis: 2.133 ± 0.217
3.961GlyIle: 3.961 ± 1.618
3.047GlyLys: 3.047 ± 0.739
5.789GlyLeu: 5.789 ± 0.438
0.914GlyMet: 0.914 ± 0.498
1.219GlyAsn: 1.219 ± 0.718
2.133GlyPro: 2.133 ± 0.84
3.656GlyGln: 3.656 ± 0.267
2.438GlyArg: 2.438 ± 0.182
2.742GlySer: 2.742 ± 0.977
2.438GlyThr: 2.438 ± 1.14
2.438GlyVal: 2.438 ± 0.182
1.219GlyTrp: 1.219 ± 0.343
2.133GlyTyr: 2.133 ± 1.699
0.0GlyXaa: 0.0 ± 0.0
His
1.828HisAla: 1.828 ± 0.132
0.609HisCys: 0.609 ± 0.267
0.914HisAsp: 0.914 ± 0.653
1.828HisGlu: 1.828 ± 0.515
1.523HisPhe: 1.523 ± 0.442
1.523HisGly: 1.523 ± 0.203
2.742HisHis: 2.742 ± 0.966
1.219HisIle: 1.219 ± 0.652
2.133HisLys: 2.133 ± 0.668
1.523HisLeu: 1.523 ± 0.203
0.609HisMet: 0.609 ± 0.267
0.914HisAsn: 0.914 ± 0.199
2.438HisPro: 2.438 ± 1.067
3.047HisGln: 3.047 ± 0.739
0.305HisArg: 0.305 ± 0.394
1.523HisSer: 1.523 ± 0.37
2.133HisThr: 2.133 ± 1.699
2.438HisVal: 2.438 ± 0.901
0.0HisTrp: 0.0 ± 0.0
1.219HisTyr: 1.219 ± 0.248
0.0HisXaa: 0.0 ± 0.0
Ile
6.703IleAla: 6.703 ± 0.263
1.219IleCys: 1.219 ± 0.652
2.742IleAsp: 2.742 ± 0.598
2.438IleGlu: 2.438 ± 0.36
2.133IlePhe: 2.133 ± 0.668
3.656IleGly: 3.656 ± 0.264
2.133IleHis: 2.133 ± 0.42
3.352IleIle: 3.352 ± 0.881
3.352IleLys: 3.352 ± 0.652
5.484IleLeu: 5.484 ± 0.135
2.133IleMet: 2.133 ± 0.548
2.133IleAsn: 2.133 ± 0.42
2.438IlePro: 2.438 ± 0.901
3.656IleGln: 3.656 ± 0.488
4.57IleArg: 4.57 ± 1.492
3.961IleSer: 3.961 ± 1.307
3.961IleThr: 3.961 ± 1.449
3.352IleVal: 3.352 ± 0.83
0.609IleTrp: 0.609 ± 0.267
3.961IleTyr: 3.961 ± 0.589
0.0IleXaa: 0.0 ± 0.0
Lys
2.133LysAla: 2.133 ± 0.694
1.219LysCys: 1.219 ± 0.248
1.523LysAsp: 1.523 ± 0.815
1.523LysGlu: 1.523 ± 0.481
2.742LysPhe: 2.742 ± 1.055
0.914LysGly: 0.914 ± 0.331
1.828LysHis: 1.828 ± 0.499
3.352LysIle: 3.352 ± 0.327
1.523LysLys: 1.523 ± 0.37
4.57LysLeu: 4.57 ± 0.975
0.914LysMet: 0.914 ± 0.199
1.828LysAsn: 1.828 ± 0.65
2.742LysPro: 2.742 ± 0.966
1.828LysGln: 1.828 ± 0.978
2.438LysArg: 2.438 ± 1.265
3.352LysSer: 3.352 ± 1.63
3.352LysThr: 3.352 ± 0.327
4.57LysVal: 4.57 ± 1.952
0.914LysTrp: 0.914 ± 0.199
2.133LysTyr: 2.133 ± 1.098
0.0LysXaa: 0.0 ± 0.0
Leu
6.703LeuAla: 6.703 ± 2.523
2.438LeuCys: 2.438 ± 0.36
6.703LeuAsp: 6.703 ± 0.655
5.18LeuGlu: 5.18 ± 0.418
3.656LeuPhe: 3.656 ± 1.223
5.789LeuGly: 5.789 ± 0.913
2.438LeuHis: 2.438 ± 0.496
5.789LeuIle: 5.789 ± 0.658
3.352LeuLys: 3.352 ± 0.301
11.883LeuLeu: 11.883 ± 1.108
1.828LeuMet: 1.828 ± 0.65
2.133LeuAsn: 2.133 ± 1.141
5.18LeuPro: 5.18 ± 0.418
3.047LeuGln: 3.047 ± 1.019
7.008LeuArg: 7.008 ± 0.57
7.313LeuSer: 7.313 ± 1.506
6.094LeuThr: 6.094 ± 1.348
8.836LeuVal: 8.836 ± 2.271
1.828LeuTrp: 1.828 ± 0.663
3.961LeuTyr: 3.961 ± 0.803
0.0LeuXaa: 0.0 ± 0.0
Met
1.828MetAla: 1.828 ± 0.65
0.305MetCys: 0.305 ± 0.163
0.914MetAsp: 0.914 ± 0.498
1.523MetGlu: 1.523 ± 0.203
0.914MetPhe: 0.914 ± 0.986
1.828MetGly: 1.828 ± 0.65
0.914MetHis: 0.914 ± 1.183
0.914MetIle: 0.914 ± 0.498
2.438MetLys: 2.438 ± 0.687
1.523MetLeu: 1.523 ± 0.481
1.219MetMet: 1.219 ± 0.652
0.914MetAsn: 0.914 ± 0.199
1.523MetPro: 1.523 ± 0.671
0.609MetGln: 0.609 ± 0.326
1.523MetArg: 1.523 ± 0.815
3.961MetSer: 3.961 ± 0.803
1.828MetThr: 1.828 ± 0.978
1.219MetVal: 1.219 ± 0.343
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.609AsnAla: 0.609 ± 0.326
0.914AsnCys: 0.914 ± 0.489
1.219AsnAsp: 1.219 ± 0.718
2.438AsnGlu: 2.438 ± 0.723
3.352AsnPhe: 3.352 ± 1.305
0.609AsnGly: 0.609 ± 0.657
0.609AsnHis: 0.609 ± 0.326
2.133AsnIle: 2.133 ± 0.339
1.219AsnLys: 1.219 ± 0.718
2.742AsnLeu: 2.742 ± 1.38
0.305AsnMet: 0.305 ± 0.448
0.914AsnAsn: 0.914 ± 0.199
2.438AsnPro: 2.438 ± 1.546
0.609AsnGln: 0.609 ± 0.267
2.438AsnArg: 2.438 ± 1.304
3.656AsnSer: 3.656 ± 1.03
2.438AsnThr: 2.438 ± 0.496
3.656AsnVal: 3.656 ± 0.488
0.305AsnTrp: 0.305 ± 0.448
1.219AsnTyr: 1.219 ± 0.38
0.0AsnXaa: 0.0 ± 0.0
Pro
4.57ProAla: 4.57 ± 2.941
1.219ProCys: 1.219 ± 0.248
2.133ProAsp: 2.133 ± 0.42
3.656ProGlu: 3.656 ± 0.264
2.742ProPhe: 2.742 ± 0.984
3.352ProGly: 3.352 ± 1.183
1.219ProHis: 1.219 ± 0.248
3.656ProIle: 3.656 ± 0.745
1.523ProLys: 1.523 ± 0.37
3.047ProLeu: 3.047 ± 0.674
1.219ProMet: 1.219 ± 1.19
2.742ProAsn: 2.742 ± 0.515
3.961ProPro: 3.961 ± 1.158
1.828ProGln: 1.828 ± 0.132
3.047ProArg: 3.047 ± 0.674
3.656ProSer: 3.656 ± 0.999
3.352ProThr: 3.352 ± 0.83
2.742ProVal: 2.742 ± 1.11
0.305ProTrp: 0.305 ± 0.163
1.219ProTyr: 1.219 ± 0.652
0.0ProXaa: 0.0 ± 0.0
Gln
4.266GlnAla: 4.266 ± 1.127
1.828GlnCys: 1.828 ± 0.65
2.438GlnAsp: 2.438 ± 0.496
2.133GlnGlu: 2.133 ± 0.217
1.828GlnPhe: 1.828 ± 0.978
2.438GlnGly: 2.438 ± 0.825
2.133GlnHis: 2.133 ± 1.141
2.133GlnIle: 2.133 ± 0.668
2.438GlnLys: 2.438 ± 0.632
5.18GlnLeu: 5.18 ± 0.756
0.914GlnMet: 0.914 ± 0.498
0.609GlnAsn: 0.609 ± 0.326
2.133GlnPro: 2.133 ± 0.339
2.133GlnGln: 2.133 ± 0.217
3.047GlnArg: 3.047 ± 0.502
2.133GlnSer: 2.133 ± 0.42
2.438GlnThr: 2.438 ± 0.36
3.047GlnVal: 3.047 ± 0.171
0.305GlnTrp: 0.305 ± 0.163
1.523GlnTyr: 1.523 ± 0.481
0.0GlnXaa: 0.0 ± 0.0
Arg
5.18ArgAla: 5.18 ± 1.414
0.609ArgCys: 0.609 ± 0.267
2.133ArgAsp: 2.133 ± 0.548
2.742ArgGlu: 2.742 ± 0.984
1.828ArgPhe: 1.828 ± 0.978
3.352ArgGly: 3.352 ± 1.183
2.742ArgHis: 2.742 ± 0.598
3.656ArgIle: 3.656 ± 0.49
3.656ArgLys: 3.656 ± 0.996
5.18ArgLeu: 5.18 ± 1.178
2.133ArgMet: 2.133 ± 0.694
1.219ArgAsn: 1.219 ± 0.38
2.438ArgPro: 2.438 ± 0.632
2.438ArgGln: 2.438 ± 0.36
3.047ArgArg: 3.047 ± 0.171
5.18ArgSer: 5.18 ± 0.756
3.961ArgThr: 3.961 ± 0.65
3.047ArgVal: 3.047 ± 0.739
0.609ArgTrp: 0.609 ± 0.267
1.219ArgTyr: 1.219 ± 0.652
0.0ArgXaa: 0.0 ± 0.0
Ser
3.656SerAla: 3.656 ± 0.701
3.047SerCys: 3.047 ± 0.171
2.742SerAsp: 2.742 ± 0.984
3.656SerGlu: 3.656 ± 0.745
3.656SerPhe: 3.656 ± 0.701
3.047SerGly: 3.047 ± 1.323
1.523SerHis: 1.523 ± 0.442
4.875SerIle: 4.875 ± 0.993
4.57SerLys: 4.57 ± 0.539
7.922SerLeu: 7.922 ± 2.279
0.305SerMet: 0.305 ± 0.233
1.828SerAsn: 1.828 ± 0.515
3.656SerPro: 3.656 ± 0.798
2.742SerGln: 2.742 ± 0.851
4.875SerArg: 4.875 ± 1.803
5.18SerSer: 5.18 ± 1.121
3.656SerThr: 3.656 ± 0.999
6.703SerVal: 6.703 ± 2.031
0.914SerTrp: 0.914 ± 0.331
2.742SerTyr: 2.742 ± 0.575
0.0SerXaa: 0.0 ± 0.0
Thr
2.438ThrAla: 2.438 ± 0.723
2.742ThrCys: 2.742 ± 0.966
2.133ThrAsp: 2.133 ± 0.548
3.961ThrGlu: 3.961 ± 0.32
2.133ThrPhe: 2.133 ± 0.42
3.656ThrGly: 3.656 ± 0.701
1.523ThrHis: 1.523 ± 0.37
4.875ThrIle: 4.875 ± 1.451
2.133ThrLys: 2.133 ± 0.217
6.703ThrLeu: 6.703 ± 1.137
1.828ThrMet: 1.828 ± 0.978
1.219ThrAsn: 1.219 ± 0.38
3.047ThrPro: 3.047 ± 0.171
3.656ThrGln: 3.656 ± 0.701
1.828ThrArg: 1.828 ± 0.61
4.875ThrSer: 4.875 ± 1.232
3.961ThrThr: 3.961 ± 0.589
3.961ThrVal: 3.961 ± 0.65
1.219ThrTrp: 1.219 ± 0.248
1.523ThrTyr: 1.523 ± 0.203
0.0ThrXaa: 0.0 ± 0.0
Val
5.484ValAla: 5.484 ± 0.496
0.914ValCys: 0.914 ± 0.199
3.656ValAsp: 3.656 ± 0.49
4.266ValGlu: 4.266 ± 0.975
3.352ValPhe: 3.352 ± 0.881
3.047ValGly: 3.047 ± 1.85
1.523ValHis: 1.523 ± 0.661
2.742ValIle: 2.742 ± 0.966
2.742ValLys: 2.742 ± 1.055
7.008ValLeu: 7.008 ± 0.166
1.828ValMet: 1.828 ± 0.8
2.438ValAsn: 2.438 ± 1.25
2.742ValPro: 2.742 ± 0.608
3.352ValGln: 3.352 ± 0.323
4.266ValArg: 4.266 ± 0.88
5.18ValSer: 5.18 ± 0.874
4.57ValThr: 4.57 ± 0.905
2.742ValVal: 2.742 ± 0.977
1.219ValTrp: 1.219 ± 0.38
3.656ValTyr: 3.656 ± 1.029
0.0ValXaa: 0.0 ± 0.0
Trp
2.133TrpAla: 2.133 ± 1.396
0.305TrpCys: 0.305 ± 0.448
0.609TrpAsp: 0.609 ± 0.326
0.305TrpGlu: 0.305 ± 0.163
0.305TrpPhe: 0.305 ± 0.163
1.219TrpGly: 1.219 ± 0.824
0.0TrpHis: 0.0 ± 0.0
0.305TrpIle: 0.305 ± 0.394
0.0TrpLys: 0.0 ± 0.0
0.609TrpLeu: 0.609 ± 0.267
0.914TrpMet: 0.914 ± 0.489
1.523TrpAsn: 1.523 ± 0.37
1.219TrpPro: 1.219 ± 0.718
0.305TrpGln: 0.305 ± 0.163
1.523TrpArg: 1.523 ± 0.481
2.133TrpSer: 2.133 ± 0.42
0.305TrpThr: 0.305 ± 0.163
0.609TrpVal: 0.609 ± 0.326
0.305TrpTrp: 0.305 ± 0.394
0.305TrpTyr: 0.305 ± 0.394
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.438TyrAla: 2.438 ± 0.759
0.0TyrCys: 0.0 ± 0.0
2.133TyrAsp: 2.133 ± 0.668
2.438TyrGlu: 2.438 ± 0.36
0.914TyrPhe: 0.914 ± 0.489
3.352TyrGly: 3.352 ± 0.327
1.219TyrHis: 1.219 ± 0.248
3.352TyrIle: 3.352 ± 0.834
0.609TyrLys: 0.609 ± 0.897
5.18TyrLeu: 5.18 ± 1.617
1.523TyrMet: 1.523 ± 0.442
0.914TyrAsn: 0.914 ± 0.199
1.828TyrPro: 1.828 ± 0.499
2.133TyrGln: 2.133 ± 0.42
1.828TyrArg: 1.828 ± 0.515
3.047TyrSer: 3.047 ± 0.171
2.438TyrThr: 2.438 ± 0.632
1.219TyrVal: 1.219 ± 0.38
1.219TyrTrp: 1.219 ± 0.343
1.219TyrTyr: 1.219 ± 0.38
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3283 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski