Amino acid dipepetide frequency for Bat cyclovirus GF-4c

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.917AlaAla: 5.917 ± 1.883
0.0AlaCys: 0.0 ± 0.0
1.972AlaAsp: 1.972 ± 1.275
3.945AlaGlu: 3.945 ± 0.304
9.862AlaPhe: 9.862 ± 0.667
1.972AlaGly: 1.972 ± 1.275
1.972AlaHis: 1.972 ± 1.579
7.89AlaIle: 7.89 ± 0.608
5.917AlaLys: 5.917 ± 0.971
3.945AlaLeu: 3.945 ± 3.158
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
1.972AlaPro: 1.972 ± 1.275
0.0AlaGln: 0.0 ± 0.0
0.0AlaArg: 0.0 ± 0.0
5.917AlaSer: 5.917 ± 1.883
5.917AlaThr: 5.917 ± 4.737
3.945AlaVal: 3.945 ± 2.55
1.972AlaTrp: 1.972 ± 1.579
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
3.945CysAla: 3.945 ± 2.55
0.0CysCys: 0.0 ± 0.0
1.972CysAsp: 1.972 ± 1.275
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
3.945CysLys: 3.945 ± 0.304
1.972CysLeu: 1.972 ± 1.275
1.972CysMet: 1.972 ± 1.275
1.972CysAsn: 1.972 ± 1.275
0.0CysPro: 0.0 ± 0.0
1.972CysGln: 1.972 ± 1.579
0.0CysArg: 0.0 ± 0.0
1.972CysSer: 1.972 ± 1.275
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.972AspAla: 1.972 ± 1.275
0.0AspCys: 0.0 ± 0.0
7.89AspAsp: 7.89 ± 2.246
5.917AspGlu: 5.917 ± 0.971
5.917AspPhe: 5.917 ± 3.825
1.972AspGly: 1.972 ± 1.275
0.0AspHis: 0.0 ± 0.0
5.917AspIle: 5.917 ± 0.971
3.945AspLys: 3.945 ± 0.304
3.945AspLeu: 3.945 ± 0.304
3.945AspMet: 3.945 ± 0.304
0.0AspAsn: 0.0 ± 0.0
0.0AspPro: 0.0 ± 0.0
1.972AspGln: 1.972 ± 1.275
1.972AspArg: 1.972 ± 1.275
0.0AspSer: 0.0 ± 0.0
0.0AspThr: 0.0 ± 0.0
0.0AspVal: 0.0 ± 0.0
0.0AspTrp: 0.0 ± 0.0
1.972AspTyr: 1.972 ± 1.275
0.0AspXaa: 0.0 ± 0.0
Glu
5.917GluAla: 5.917 ± 3.825
0.0GluCys: 0.0 ± 0.0
1.972GluAsp: 1.972 ± 1.275
3.945GluGlu: 3.945 ± 2.55
3.945GluPhe: 3.945 ± 0.304
3.945GluGly: 3.945 ± 2.55
3.945GluHis: 3.945 ± 0.304
1.972GluIle: 1.972 ± 1.579
3.945GluLys: 3.945 ± 0.304
3.945GluLeu: 3.945 ± 0.304
1.972GluMet: 1.972 ± 1.275
5.917GluAsn: 5.917 ± 0.971
1.972GluPro: 1.972 ± 1.275
3.945GluGln: 3.945 ± 2.55
1.972GluArg: 1.972 ± 1.579
1.972GluSer: 1.972 ± 1.579
0.0GluThr: 0.0 ± 0.0
1.972GluVal: 1.972 ± 1.579
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.972PheAla: 1.972 ± 1.579
1.972PheCys: 1.972 ± 1.275
0.0PheAsp: 0.0 ± 0.0
11.834PheGlu: 11.834 ± 0.912
1.972PhePhe: 1.972 ± 1.275
3.945PheGly: 3.945 ± 3.158
0.0PheHis: 0.0 ± 0.0
7.89PheIle: 7.89 ± 2.246
1.972PheLys: 1.972 ± 1.275
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.972PhePro: 1.972 ± 1.579
1.972PheGln: 1.972 ± 1.275
1.972PheArg: 1.972 ± 1.579
3.945PheSer: 3.945 ± 0.304
3.945PheThr: 3.945 ± 2.55
3.945PheVal: 3.945 ± 3.158
0.0PheTrp: 0.0 ± 0.0
1.972PheTyr: 1.972 ± 1.275
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
1.972GlyAsp: 1.972 ± 1.275
1.972GlyGlu: 1.972 ± 1.275
5.917GlyPhe: 5.917 ± 0.971
1.972GlyGly: 1.972 ± 1.275
0.0GlyHis: 0.0 ± 0.0
3.945GlyIle: 3.945 ± 2.55
5.917GlyLys: 5.917 ± 3.825
3.945GlyLeu: 3.945 ± 2.55
0.0GlyMet: 0.0 ± 0.0
1.972GlyAsn: 1.972 ± 1.275
0.0GlyPro: 0.0 ± 0.0
1.972GlyGln: 1.972 ± 1.579
5.917GlyArg: 5.917 ± 4.737
3.945GlySer: 3.945 ± 0.304
3.945GlyThr: 3.945 ± 2.55
3.945GlyVal: 3.945 ± 0.304
1.972GlyTrp: 1.972 ± 1.275
3.945GlyTyr: 3.945 ± 2.55
0.0GlyXaa: 0.0 ± 0.0
His
1.972HisAla: 1.972 ± 1.275
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
3.945HisIle: 3.945 ± 0.304
0.0HisLys: 0.0 ± 0.0
3.945HisLeu: 3.945 ± 0.304
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.945HisPro: 3.945 ± 2.55
0.0HisGln: 0.0 ± 0.0
1.972HisArg: 1.972 ± 1.275
1.972HisSer: 1.972 ± 1.579
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.972HisTyr: 1.972 ± 1.579
0.0HisXaa: 0.0 ± 0.0
Ile
3.945IleAla: 3.945 ± 0.304
1.972IleCys: 1.972 ± 1.275
5.917IleAsp: 5.917 ± 0.971
3.945IleGlu: 3.945 ± 0.304
1.972IlePhe: 1.972 ± 1.275
3.945IleGly: 3.945 ± 0.304
3.945IleHis: 3.945 ± 2.55
1.972IleIle: 1.972 ± 1.275
13.807IleLys: 13.807 ± 6.071
3.945IleLeu: 3.945 ± 3.158
0.0IleMet: 0.0 ± 1.05
3.945IleAsn: 3.945 ± 3.158
3.945IlePro: 3.945 ± 3.158
3.945IleGln: 3.945 ± 3.158
1.972IleArg: 1.972 ± 1.275
1.972IleSer: 1.972 ± 1.579
3.945IleThr: 3.945 ± 2.55
3.945IleVal: 3.945 ± 0.304
1.972IleTrp: 1.972 ± 1.275
7.89IleTyr: 7.89 ± 0.608
0.0IleXaa: 0.0 ± 0.0
Lys
5.917LysAla: 5.917 ± 0.971
1.972LysCys: 1.972 ± 1.275
0.0LysAsp: 0.0 ± 0.0
3.945LysGlu: 3.945 ± 0.304
1.972LysPhe: 1.972 ± 1.275
3.945LysGly: 3.945 ± 2.55
1.972LysHis: 1.972 ± 1.275
7.89LysIle: 7.89 ± 3.462
3.945LysLys: 3.945 ± 0.304
5.917LysLeu: 5.917 ± 1.883
3.945LysMet: 3.945 ± 1.164
1.972LysAsn: 1.972 ± 1.579
7.89LysPro: 7.89 ± 2.246
5.917LysGln: 5.917 ± 4.737
5.917LysArg: 5.917 ± 3.825
3.945LysSer: 3.945 ± 2.55
3.945LysThr: 3.945 ± 2.55
3.945LysVal: 3.945 ± 0.304
0.0LysTrp: 0.0 ± 0.0
9.862LysTyr: 9.862 ± 3.521
0.0LysXaa: 0.0 ± 0.0
Leu
1.972LeuAla: 1.972 ± 1.579
0.0LeuCys: 0.0 ± 0.0
0.0LeuAsp: 0.0 ± 0.0
3.945LeuGlu: 3.945 ± 2.55
0.0LeuPhe: 0.0 ± 0.0
0.0LeuGly: 0.0 ± 0.0
3.945LeuHis: 3.945 ± 3.158
1.972LeuIle: 1.972 ± 1.275
5.917LeuLys: 5.917 ± 0.971
3.945LeuLeu: 3.945 ± 2.55
0.0LeuMet: 0.0 ± 0.0
1.972LeuAsn: 1.972 ± 1.579
1.972LeuPro: 1.972 ± 1.275
1.972LeuGln: 1.972 ± 1.275
5.917LeuArg: 5.917 ± 4.737
7.89LeuSer: 7.89 ± 0.608
1.972LeuThr: 1.972 ± 1.579
3.945LeuVal: 3.945 ± 3.158
1.972LeuTrp: 1.972 ± 1.275
3.945LeuTyr: 3.945 ± 0.304
0.0LeuXaa: 0.0 ± 0.0
Met
3.945MetAla: 3.945 ± 3.158
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
3.945MetGlu: 3.945 ± 2.55
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.972MetIle: 1.972 ± 1.579
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
3.945MetAsn: 3.945 ± 0.304
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.972MetArg: 1.972 ± 1.275
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
1.972MetVal: 1.972 ± 1.275
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.972AsnAla: 1.972 ± 1.275
1.972AsnCys: 1.972 ± 1.275
0.0AsnAsp: 0.0 ± 0.0
0.0AsnGlu: 0.0 ± 0.0
3.945AsnPhe: 3.945 ± 3.158
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
7.89AsnLys: 7.89 ± 0.608
5.917AsnLeu: 5.917 ± 1.883
0.0AsnMet: 0.0 ± 0.0
3.945AsnAsn: 3.945 ± 0.304
0.0AsnPro: 0.0 ± 0.0
3.945AsnGln: 3.945 ± 0.304
1.972AsnArg: 1.972 ± 1.579
9.862AsnSer: 9.862 ± 0.667
1.972AsnThr: 1.972 ± 1.579
7.89AsnVal: 7.89 ± 0.608
0.0AsnTrp: 0.0 ± 0.0
1.972AsnTyr: 1.972 ± 1.275
0.0AsnXaa: 0.0 ± 0.0
Pro
7.89ProAla: 7.89 ± 6.316
3.945ProCys: 3.945 ± 0.304
0.0ProAsp: 0.0 ± 0.0
1.972ProGlu: 1.972 ± 1.579
1.972ProPhe: 1.972 ± 1.579
1.972ProGly: 1.972 ± 1.275
1.972ProHis: 1.972 ± 1.275
1.972ProIle: 1.972 ± 1.275
0.0ProLys: 0.0 ± 0.0
0.0ProLeu: 0.0 ± 0.0
1.972ProMet: 1.972 ± 1.275
3.945ProAsn: 3.945 ± 3.158
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
5.917ProArg: 5.917 ± 0.971
0.0ProSer: 0.0 ± 0.0
1.972ProThr: 1.972 ± 1.275
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
5.917ProTyr: 5.917 ± 0.971
0.0ProXaa: 0.0 ± 0.0
Gln
1.972GlnAla: 1.972 ± 1.579
0.0GlnCys: 0.0 ± 0.0
1.972GlnAsp: 1.972 ± 1.579
3.945GlnGlu: 3.945 ± 0.304
0.0GlnPhe: 0.0 ± 0.0
5.917GlnGly: 5.917 ± 3.825
0.0GlnHis: 0.0 ± 0.0
3.945GlnIle: 3.945 ± 0.304
1.972GlnLys: 1.972 ± 1.275
3.945GlnLeu: 3.945 ± 0.304
0.0GlnMet: 0.0 ± 0.0
3.945GlnAsn: 3.945 ± 0.304
0.0GlnPro: 0.0 ± 0.0
1.972GlnGln: 1.972 ± 1.275
1.972GlnArg: 1.972 ± 1.579
0.0GlnSer: 0.0 ± 0.0
3.945GlnThr: 3.945 ± 0.304
1.972GlnVal: 1.972 ± 1.579
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.945ArgAla: 3.945 ± 0.304
0.0ArgCys: 0.0 ± 0.0
3.945ArgAsp: 3.945 ± 2.55
0.0ArgGlu: 0.0 ± 0.0
7.89ArgPhe: 7.89 ± 0.608
3.945ArgGly: 3.945 ± 2.55
0.0ArgHis: 0.0 ± 0.0
9.862ArgIle: 9.862 ± 2.187
5.917ArgLys: 5.917 ± 4.737
3.945ArgLeu: 3.945 ± 0.304
0.0ArgMet: 0.0 ± 0.0
1.972ArgAsn: 1.972 ± 1.579
3.945ArgPro: 3.945 ± 3.158
1.972ArgGln: 1.972 ± 1.275
25.641ArgArg: 25.641 ± 11.966
1.972ArgSer: 1.972 ± 1.579
3.945ArgThr: 3.945 ± 0.304
1.972ArgVal: 1.972 ± 1.579
0.0ArgTrp: 0.0 ± 0.0
1.972ArgTyr: 1.972 ± 1.275
0.0ArgXaa: 0.0 ± 0.0
Ser
5.917SerAla: 5.917 ± 0.971
0.0SerCys: 0.0 ± 0.0
5.917SerAsp: 5.917 ± 1.883
1.972SerGlu: 1.972 ± 1.275
1.972SerPhe: 1.972 ± 1.579
3.945SerGly: 3.945 ± 3.158
0.0SerHis: 0.0 ± 0.0
7.89SerIle: 7.89 ± 0.608
5.917SerLys: 5.917 ± 3.825
1.972SerLeu: 1.972 ± 1.275
1.972SerMet: 1.972 ± 1.579
11.834SerAsn: 11.834 ± 0.912
3.945SerPro: 3.945 ± 3.158
0.0SerGln: 0.0 ± 0.0
1.972SerArg: 1.972 ± 1.275
1.972SerSer: 1.972 ± 1.579
3.945SerThr: 3.945 ± 3.158
5.917SerVal: 5.917 ± 4.737
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
3.945ThrCys: 3.945 ± 2.55
3.945ThrAsp: 3.945 ± 2.55
0.0ThrGlu: 0.0 ± 0.0
0.0ThrPhe: 0.0 ± 0.0
7.89ThrGly: 7.89 ± 0.608
0.0ThrHis: 0.0 ± 0.0
3.945ThrIle: 3.945 ± 0.304
0.0ThrLys: 0.0 ± 0.0
0.0ThrLeu: 0.0 ± 0.0
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
1.972ThrPro: 1.972 ± 1.579
1.972ThrGln: 1.972 ± 1.275
5.917ThrArg: 5.917 ± 4.737
7.89ThrSer: 7.89 ± 0.608
3.945ThrThr: 3.945 ± 0.304
3.945ThrVal: 3.945 ± 0.304
1.972ThrTrp: 1.972 ± 1.275
1.972ThrTyr: 1.972 ± 1.275
0.0ThrXaa: 0.0 ± 0.0
Val
1.972ValAla: 1.972 ± 1.579
0.0ValCys: 0.0 ± 0.0
3.945ValAsp: 3.945 ± 0.304
1.972ValGlu: 1.972 ± 1.275
1.972ValPhe: 1.972 ± 1.579
1.972ValGly: 1.972 ± 1.275
0.0ValHis: 0.0 ± 0.0
3.945ValIle: 3.945 ± 0.304
3.945ValLys: 3.945 ± 3.158
1.972ValLeu: 1.972 ± 1.579
0.0ValMet: 0.0 ± 0.0
1.972ValAsn: 1.972 ± 1.275
5.917ValPro: 5.917 ± 1.883
3.945ValGln: 3.945 ± 0.304
7.89ValArg: 7.89 ± 0.608
5.917ValSer: 5.917 ± 4.737
1.972ValThr: 1.972 ± 1.579
5.917ValVal: 5.917 ± 1.883
0.0ValTrp: 0.0 ± 0.0
3.945ValTyr: 3.945 ± 0.304
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.972TrpAsp: 1.972 ± 1.275
0.0TrpGlu: 0.0 ± 0.0
1.972TrpPhe: 1.972 ± 1.579
1.972TrpGly: 1.972 ± 1.275
0.0TrpHis: 0.0 ± 0.0
3.945TrpIle: 3.945 ± 2.55
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.972TrpAsn: 1.972 ± 1.275
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
1.972TrpTrp: 1.972 ± 1.275
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.972TyrAla: 1.972 ± 1.579
3.945TyrCys: 3.945 ± 0.304
3.945TyrAsp: 3.945 ± 2.55
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
3.945TyrGly: 3.945 ± 2.55
1.972TyrHis: 1.972 ± 1.275
0.0TyrIle: 0.0 ± 0.0
9.862TyrLys: 9.862 ± 0.667
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
1.972TyrAsn: 1.972 ± 1.275
1.972TyrPro: 1.972 ± 1.275
0.0TyrGln: 0.0 ± 0.0
1.972TyrArg: 1.972 ± 1.275
5.917TyrSer: 5.917 ± 1.883
3.945TyrThr: 3.945 ± 2.55
3.945TyrVal: 3.945 ± 0.304
1.972TyrTrp: 1.972 ± 1.275
5.917TyrTyr: 5.917 ± 3.825
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (508 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski