Amino acid dipepetide frequency for Lake Sarah-associated circular virus-6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.906AlaAla: 3.906 ± 2.42
0.0AlaCys: 0.0 ± 0.0
2.604AlaAsp: 2.604 ± 0.344
1.302AlaGlu: 1.302 ± 1.151
2.604AlaPhe: 2.604 ± 0.344
6.51AlaGly: 6.51 ± 2.076
0.0AlaHis: 0.0 ± 0.0
1.302AlaIle: 1.302 ± 0.807
5.208AlaLys: 5.208 ± 1.269
3.906AlaLeu: 3.906 ± 1.495
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
2.604AlaPro: 2.604 ± 1.613
3.906AlaGln: 3.906 ± 2.42
1.302AlaArg: 1.302 ± 1.151
9.115AlaSer: 9.115 ± 3.69
5.208AlaThr: 5.208 ± 1.269
6.51AlaVal: 6.51 ± 0.119
1.302AlaTrp: 1.302 ± 1.151
2.604AlaTyr: 2.604 ± 0.344
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.302CysAsp: 1.302 ± 1.151
0.0CysGlu: 0.0 ± 0.0
1.302CysPhe: 1.302 ± 0.807
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.302CysLys: 1.302 ± 1.151
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
3.906CysAsn: 3.906 ± 1.495
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.302CysThr: 1.302 ± 0.807
2.604CysVal: 2.604 ± 0.344
1.302CysTrp: 1.302 ± 1.151
1.302CysTyr: 1.302 ± 1.151
0.0CysXaa: 0.0 ± 0.0
Asp
2.604AspAla: 2.604 ± 0.344
1.302AspCys: 1.302 ± 1.151
3.906AspAsp: 3.906 ± 3.453
3.906AspGlu: 3.906 ± 3.453
2.604AspPhe: 2.604 ± 0.344
3.906AspGly: 3.906 ± 1.495
2.604AspHis: 2.604 ± 2.302
2.604AspIle: 2.604 ± 2.302
0.0AspLys: 0.0 ± 0.0
9.115AspLeu: 9.115 ± 1.732
1.302AspMet: 1.302 ± 1.151
2.604AspAsn: 2.604 ± 2.302
2.604AspPro: 2.604 ± 0.344
1.302AspGln: 1.302 ± 0.807
1.302AspArg: 1.302 ± 0.807
6.51AspSer: 6.51 ± 0.119
0.0AspThr: 0.0 ± 0.0
0.0AspVal: 0.0 ± 0.0
2.604AspTrp: 2.604 ± 2.302
1.302AspTyr: 1.302 ± 1.151
0.0AspXaa: 0.0 ± 0.0
Glu
1.302GluAla: 1.302 ± 1.151
0.0GluCys: 0.0 ± 0.0
5.208GluAsp: 5.208 ± 4.603
6.51GluGlu: 6.51 ± 3.797
0.0GluPhe: 0.0 ± 0.0
1.302GluGly: 1.302 ± 1.151
3.906GluHis: 3.906 ± 3.453
1.302GluIle: 1.302 ± 1.151
0.0GluLys: 0.0 ± 0.0
1.302GluLeu: 1.302 ± 1.151
0.0GluMet: 0.0 ± 0.0
2.604GluAsn: 2.604 ± 0.344
2.604GluPro: 2.604 ± 0.344
2.604GluGln: 2.604 ± 0.344
5.208GluArg: 5.208 ± 4.603
3.906GluSer: 3.906 ± 1.495
3.906GluThr: 3.906 ± 0.463
0.0GluVal: 0.0 ± 0.0
1.302GluTrp: 1.302 ± 0.807
2.604GluTyr: 2.604 ± 0.344
0.0GluXaa: 0.0 ± 0.0
Phe
3.906PheAla: 3.906 ± 0.463
2.604PheCys: 2.604 ± 0.344
2.604PheAsp: 2.604 ± 0.344
0.0PheGlu: 0.0 ± 0.0
2.604PhePhe: 2.604 ± 1.613
2.604PheGly: 2.604 ± 1.613
1.302PheHis: 1.302 ± 1.151
2.604PheIle: 2.604 ± 1.613
2.604PheLys: 2.604 ± 0.344
2.604PheLeu: 2.604 ± 1.613
5.208PheMet: 5.208 ± 0.984
1.302PheAsn: 1.302 ± 0.807
1.302PhePro: 1.302 ± 1.151
3.906PheGln: 3.906 ± 0.463
3.906PheArg: 3.906 ± 0.463
2.604PheSer: 2.604 ± 0.344
2.604PheThr: 2.604 ± 1.613
3.906PheVal: 3.906 ± 1.495
0.0PheTrp: 0.0 ± 0.0
2.604PheTyr: 2.604 ± 1.613
0.0PheXaa: 0.0 ± 0.0
Gly
3.906GlyAla: 3.906 ± 2.42
0.0GlyCys: 0.0 ± 0.0
1.302GlyAsp: 1.302 ± 0.807
1.302GlyGlu: 1.302 ± 0.807
2.604GlyPhe: 2.604 ± 1.613
3.906GlyGly: 3.906 ± 2.42
2.604GlyHis: 2.604 ± 0.344
0.0GlyIle: 0.0 ± 0.0
5.208GlyLys: 5.208 ± 2.646
5.208GlyLeu: 5.208 ± 1.269
1.302GlyMet: 1.302 ± 0.807
2.604GlyAsn: 2.604 ± 1.613
1.302GlyPro: 1.302 ± 0.807
5.208GlyGln: 5.208 ± 2.646
1.302GlyArg: 1.302 ± 0.807
3.906GlySer: 3.906 ± 0.463
2.604GlyThr: 2.604 ± 1.613
6.51GlyVal: 6.51 ± 2.076
0.0GlyTrp: 0.0 ± 0.0
1.302GlyTyr: 1.302 ± 0.807
0.0GlyXaa: 0.0 ± 0.0
His
2.604HisAla: 2.604 ± 2.302
1.302HisCys: 1.302 ± 1.151
0.0HisAsp: 0.0 ± 0.0
2.604HisGlu: 2.604 ± 2.302
1.302HisPhe: 1.302 ± 1.151
1.302HisGly: 1.302 ± 0.807
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.604HisLys: 2.604 ± 2.302
2.604HisLeu: 2.604 ± 0.344
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.302HisPro: 1.302 ± 0.807
0.0HisGln: 0.0 ± 0.0
1.302HisArg: 1.302 ± 1.151
2.604HisSer: 2.604 ± 1.613
1.302HisThr: 1.302 ± 1.151
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.302IleAla: 1.302 ± 0.807
0.0IleCys: 0.0 ± 0.0
6.51IleAsp: 6.51 ± 3.797
1.302IleGlu: 1.302 ± 1.151
1.302IlePhe: 1.302 ± 1.151
1.302IleGly: 1.302 ± 0.807
0.0IleHis: 0.0 ± 0.0
6.51IleIle: 6.51 ± 3.797
2.604IleLys: 2.604 ± 2.302
7.812IleLeu: 7.812 ± 0.925
1.302IleMet: 1.302 ± 1.151
3.906IleAsn: 3.906 ± 0.463
0.0IlePro: 0.0 ± 0.0
5.208IleGln: 5.208 ± 1.269
3.906IleArg: 3.906 ± 1.495
1.302IleSer: 1.302 ± 1.151
2.604IleThr: 2.604 ± 1.613
2.604IleVal: 2.604 ± 2.302
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
3.906LysAsp: 3.906 ± 3.453
3.906LysGlu: 3.906 ± 3.453
1.302LysPhe: 1.302 ± 1.151
1.302LysGly: 1.302 ± 1.151
1.302LysHis: 1.302 ± 1.151
5.208LysIle: 5.208 ± 2.646
6.51LysLys: 6.51 ± 5.754
2.604LysLeu: 2.604 ± 0.344
0.0LysMet: 0.0 ± 0.0
7.812LysAsn: 7.812 ± 1.032
2.604LysPro: 2.604 ± 2.302
10.417LysGln: 10.417 ± 0.581
6.51LysArg: 6.51 ± 0.119
2.604LysSer: 2.604 ± 0.344
5.208LysThr: 5.208 ± 0.688
3.906LysVal: 3.906 ± 2.42
3.906LysTrp: 3.906 ± 0.463
1.302LysTyr: 1.302 ± 1.151
0.0LysXaa: 0.0 ± 0.0
Leu
2.604LeuAla: 2.604 ± 1.613
2.604LeuCys: 2.604 ± 0.344
2.604LeuAsp: 2.604 ± 0.344
3.906LeuGlu: 3.906 ± 1.495
1.302LeuPhe: 1.302 ± 0.807
3.906LeuGly: 3.906 ± 1.495
1.302LeuHis: 1.302 ± 1.151
3.906LeuIle: 3.906 ± 1.495
6.51LeuLys: 6.51 ± 0.119
5.208LeuLeu: 5.208 ± 1.269
0.0LeuMet: 0.0 ± 0.0
7.812LeuAsn: 7.812 ± 2.883
9.115LeuPro: 9.115 ± 3.69
1.302LeuGln: 1.302 ± 0.807
2.604LeuArg: 2.604 ± 1.613
5.208LeuSer: 5.208 ± 2.646
6.51LeuThr: 6.51 ± 0.119
3.906LeuVal: 3.906 ± 2.42
0.0LeuTrp: 0.0 ± 0.0
2.604LeuTyr: 2.604 ± 2.302
0.0LeuXaa: 0.0 ± 0.0
Met
1.302MetAla: 1.302 ± 0.807
0.0MetCys: 0.0 ± 0.0
1.302MetAsp: 1.302 ± 1.151
5.208MetGlu: 5.208 ± 2.646
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.302MetLys: 1.302 ± 1.151
1.302MetLeu: 1.302 ± 0.807
0.0MetMet: 0.0 ± 0.0
1.302MetAsn: 1.302 ± 1.151
1.302MetPro: 1.302 ± 0.807
1.302MetGln: 1.302 ± 0.807
1.302MetArg: 1.302 ± 1.151
2.604MetSer: 2.604 ± 0.344
5.208MetThr: 5.208 ± 3.227
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.208AsnAla: 5.208 ± 0.688
0.0AsnCys: 0.0 ± 0.0
1.302AsnAsp: 1.302 ± 1.151
2.604AsnGlu: 2.604 ± 2.302
2.604AsnPhe: 2.604 ± 0.344
1.302AsnGly: 1.302 ± 0.807
2.604AsnHis: 2.604 ± 0.344
6.51AsnIle: 6.51 ± 1.839
10.417AsnLys: 10.417 ± 0.581
7.812AsnLeu: 7.812 ± 2.99
2.604AsnMet: 2.604 ± 1.118
5.208AsnAsn: 5.208 ± 1.269
2.604AsnPro: 2.604 ± 1.613
0.0AsnGln: 0.0 ± 0.0
1.302AsnArg: 1.302 ± 0.807
3.906AsnSer: 3.906 ± 2.42
5.208AsnThr: 5.208 ± 0.688
5.208AsnVal: 5.208 ± 3.227
2.604AsnTrp: 2.604 ± 0.344
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
9.115ProAla: 9.115 ± 3.69
0.0ProCys: 0.0 ± 0.0
2.604ProAsp: 2.604 ± 0.344
0.0ProGlu: 0.0 ± 0.0
1.302ProPhe: 1.302 ± 0.807
2.604ProGly: 2.604 ± 0.344
1.302ProHis: 1.302 ± 1.151
6.51ProIle: 6.51 ± 0.119
2.604ProLys: 2.604 ± 2.302
2.604ProLeu: 2.604 ± 0.344
2.604ProMet: 2.604 ± 0.344
3.906ProAsn: 3.906 ± 0.463
3.906ProPro: 3.906 ± 0.463
1.302ProGln: 1.302 ± 1.151
0.0ProArg: 0.0 ± 0.0
1.302ProSer: 1.302 ± 0.807
3.906ProThr: 3.906 ± 2.42
3.906ProVal: 3.906 ± 0.463
1.302ProTrp: 1.302 ± 0.807
1.302ProTyr: 1.302 ± 0.807
0.0ProXaa: 0.0 ± 0.0
Gln
3.906GlnAla: 3.906 ± 2.42
1.302GlnCys: 1.302 ± 1.151
1.302GlnAsp: 1.302 ± 0.807
0.0GlnGlu: 0.0 ± 0.0
2.604GlnPhe: 2.604 ± 0.344
6.51GlnGly: 6.51 ± 2.076
1.302GlnHis: 1.302 ± 0.807
0.0GlnIle: 0.0 ± 0.0
6.51GlnLys: 6.51 ± 1.839
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
6.51GlnAsn: 6.51 ± 0.119
2.604GlnPro: 2.604 ± 0.344
2.604GlnGln: 2.604 ± 1.613
5.208GlnArg: 5.208 ± 1.269
2.604GlnSer: 2.604 ± 0.344
6.51GlnThr: 6.51 ± 4.034
2.604GlnVal: 2.604 ± 0.344
0.0GlnTrp: 0.0 ± 0.0
1.302GlnTyr: 1.302 ± 0.807
0.0GlnXaa: 0.0 ± 0.0
Arg
3.906ArgAla: 3.906 ± 0.463
0.0ArgCys: 0.0 ± 0.0
3.906ArgAsp: 3.906 ± 1.495
2.604ArgGlu: 2.604 ± 0.344
2.604ArgPhe: 2.604 ± 0.344
1.302ArgGly: 1.302 ± 0.807
0.0ArgHis: 0.0 ± 0.0
0.0ArgIle: 0.0 ± 0.0
2.604ArgLys: 2.604 ± 1.613
2.604ArgLeu: 2.604 ± 0.344
1.302ArgMet: 1.302 ± 0.807
7.812ArgAsn: 7.812 ± 1.032
1.302ArgPro: 1.302 ± 1.151
1.302ArgGln: 1.302 ± 1.151
2.604ArgArg: 2.604 ± 0.344
1.302ArgSer: 1.302 ± 0.807
1.302ArgThr: 1.302 ± 0.807
1.302ArgVal: 1.302 ± 0.807
2.604ArgTrp: 2.604 ± 1.613
5.208ArgTyr: 5.208 ± 0.688
0.0ArgXaa: 0.0 ± 0.0
Ser
3.906SerAla: 3.906 ± 0.463
1.302SerCys: 1.302 ± 1.151
3.906SerAsp: 3.906 ± 0.463
2.604SerGlu: 2.604 ± 0.344
13.021SerPhe: 13.021 ± 4.152
5.208SerGly: 5.208 ± 3.227
1.302SerHis: 1.302 ± 0.807
0.0SerIle: 0.0 ± 0.0
3.906SerLys: 3.906 ± 1.495
5.208SerLeu: 5.208 ± 3.227
1.302SerMet: 1.302 ± 0.807
3.906SerAsn: 3.906 ± 0.463
6.51SerPro: 6.51 ± 1.839
5.208SerGln: 5.208 ± 1.269
0.0SerArg: 0.0 ± 0.0
5.208SerSer: 5.208 ± 1.269
9.115SerThr: 9.115 ± 1.732
2.604SerVal: 2.604 ± 0.344
0.0SerTrp: 0.0 ± 0.0
2.604SerTyr: 2.604 ± 1.613
0.0SerXaa: 0.0 ± 0.0
Thr
2.604ThrAla: 2.604 ± 0.344
2.604ThrCys: 2.604 ± 1.613
3.906ThrAsp: 3.906 ± 2.42
3.906ThrGlu: 3.906 ± 0.463
6.51ThrPhe: 6.51 ± 0.119
6.51ThrGly: 6.51 ± 4.034
1.302ThrHis: 1.302 ± 0.807
3.906ThrIle: 3.906 ± 1.495
1.302ThrLys: 1.302 ± 1.151
2.604ThrLeu: 2.604 ± 1.613
3.906ThrMet: 3.906 ± 1.495
3.906ThrAsn: 3.906 ± 0.463
6.51ThrPro: 6.51 ± 4.034
2.604ThrGln: 2.604 ± 1.613
3.906ThrArg: 3.906 ± 2.42
6.51ThrSer: 6.51 ± 4.034
3.906ThrThr: 3.906 ± 0.463
9.115ThrVal: 9.115 ± 5.647
0.0ThrTrp: 0.0 ± 0.0
3.906ThrTyr: 3.906 ± 3.453
0.0ThrXaa: 0.0 ± 0.0
Val
5.208ValAla: 5.208 ± 0.688
1.302ValCys: 1.302 ± 1.151
2.604ValAsp: 2.604 ± 0.344
1.302ValGlu: 1.302 ± 0.807
2.604ValPhe: 2.604 ± 1.613
1.302ValGly: 1.302 ± 0.807
0.0ValHis: 0.0 ± 0.0
3.906ValIle: 3.906 ± 2.42
1.302ValLys: 1.302 ± 0.807
7.812ValLeu: 7.812 ± 1.032
1.302ValMet: 1.302 ± 1.151
2.604ValAsn: 2.604 ± 0.344
1.302ValPro: 1.302 ± 1.151
3.906ValGln: 3.906 ± 2.42
1.302ValArg: 1.302 ± 0.807
10.417ValSer: 10.417 ± 4.496
7.812ValThr: 7.812 ± 2.883
3.906ValVal: 3.906 ± 0.463
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.302TrpAla: 1.302 ± 0.807
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.604TrpGlu: 2.604 ± 2.302
1.302TrpPhe: 1.302 ± 0.807
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.302TrpIle: 1.302 ± 1.151
2.604TrpLys: 2.604 ± 2.302
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.302TrpPro: 1.302 ± 1.151
0.0TrpGln: 0.0 ± 0.0
1.302TrpArg: 1.302 ± 0.807
5.208TrpSer: 5.208 ± 1.269
1.302TrpThr: 1.302 ± 0.807
1.302TrpVal: 1.302 ± 1.151
1.302TrpTrp: 1.302 ± 1.151
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.302TyrAla: 1.302 ± 1.151
0.0TyrCys: 0.0 ± 0.0
1.302TyrAsp: 1.302 ± 1.151
0.0TyrGlu: 0.0 ± 0.0
1.302TyrPhe: 1.302 ± 0.807
1.302TyrGly: 1.302 ± 1.151
0.0TyrHis: 0.0 ± 0.0
3.906TyrIle: 3.906 ± 1.495
5.208TyrLys: 5.208 ± 0.688
2.604TyrLeu: 2.604 ± 0.344
0.0TyrMet: 0.0 ± 0.0
2.604TyrAsn: 2.604 ± 0.344
1.302TyrPro: 1.302 ± 0.807
1.302TyrGln: 1.302 ± 0.807
1.302TyrArg: 1.302 ± 0.807
0.0TyrSer: 0.0 ± 0.0
3.906TyrThr: 3.906 ± 0.463
0.0TyrVal: 0.0 ± 0.0
2.604TyrTrp: 2.604 ± 2.302
1.302TyrTyr: 1.302 ± 0.807
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (769 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski